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Gene Dmel\CG10561

General Information
Symbol	Dmel\CG10561	Species	D. melanogaster
Name		Annotation symbol	CG10561
Feature type	protein_coding_gene	FlyBase ID	FBgn0002036
Gene Model Status	Current	Stock availability	3 publicly available
Also Known As	cs, TU37C2
Genomic Location
Chromosome (arm)	2L	Recombination map	2-53.9
Cytogenetic map	37C1-37C1	Sequence location	2L:19,114,401..19,116,571 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG10561 (FBgn0002036). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: oxidoreductase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: oxidation-reduction process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Amine oxidase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, adult hindgut, adult Malpighian tubules, adult heart, larval fat body, adult salivary gland, adult spermathecae, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1623061_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG10561. Gene sequence location is 2L:19114401..19116571.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features BKN25408 HFA02068
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 37C1-37C1   Limits computationally determined from genome sequence between P{lacW}l(2)37Dbk16106&P{lacW}Catsupk05424 and P{lacW}Ddck02104
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location	2-53.9
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG10561 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG10561-RA FBtr0081155  NM_057260   2053   504
Additional Transcript Data & Comments
Reported size (kB)	2.0 (northern blot) (Spencer et al., 1986, Marsh et al., 1986)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG10561-PA   FBpp0080699   56.2   504   8.45     NP_476608   AAF53761
Additional Polypeptide Data & Comments
Reported size (kDa)	504 (aa) (Tatarenkov et al., 1999)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Amine oxidase (IPR002937)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014134 AAF53761   AC005440   AC007176   AF091328 AAC67581   AI403410   AI404839   AI945547   AW940874   AY058445 AAL13674   BE977572   BF485587   BF486695   BF490458   BF491217   BF491879   BF491927   BF492192   BF494418   BF499730   BF502463   BF502703   BF504571   BF505865   BG635206   BT044166   CO264597   X05991 CAA29405   X05991 CAA29406   X05991 CAA29407   X05991 CAA29408
UniProtKB/Swiss-Prot	P18487
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
dot blot Stage Tissue/Position (including subcellular localization) Reference adult stage | male   adult head   (Spencer et al., 1986) adult thorax   (Spencer et al., 1986) adult stage | female   adult head   (Spencer et al., 1986) adult thorax   (Spencer et al., 1986) adult abdomen   (Spencer et al., 1986) adult stage   ovary   (Spencer et al., 1986) testis   (Spencer et al., 1986) northern blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage     (Spencer et al., 1986) third instar larval stage     (Spencer et al., 1986) adult stage     (Spencer et al., 1986)
Additional Descriptive Data
	CG10561 transcripts are detected at low levels in maleand female heads and thoraces, and in female abdomens and ovaries, but at high levels in testes. (Spencer et al., 1986) CG10561 transcripts are detected at very high levels in 1 hr embryos, at high levels in 2 and 8 hr embryos, and at lower levels in 14 hr embryos and in mature larvae. Expression is also detected in adults. (Spencer et al., 1986)
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0002036    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0002036 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0002036 expression level Developmental Stage   Expression Level embryo 00-02hr    963 embryo 02-04hr    202 embryo 04-06hr    52 embryo 06-08hr    178 embryo 08-10hr    321 embryo 10-12hr    448 embryo 12-14hr    365 embryo 14-16hr    433 embryo 16-18hr    383 embryo 18-20hr    437 embryo 20-22hr    464 embryo 22-24hr    417 larva L1    334 larva L2    346 larva L3 12hr old    397 larva L3 puffstage 1-2    396 larva L3 puffstage 3-6    578 larva L3 puffstage 7-9    660 white prepupae new    635 white prepupae 12hr    1048 white prepupae 24hr    1448 pupae 2d postWPP    2067 pupae 3d postWPP    3006 pupae 4d postWPP    3197 adult male 01day    5172 adult male 05day    5958 adult male 30day    5612 adult female 01day    1158 adult female 05day    746 adult female 30day    776 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (963) embryo 02-04hr  (202) embryo 04-06hr    52 embryo 06-08hr  (178) embryo 08-10hr  (321) embryo 10-12hr  (448) embryo 12-14hr  (365) embryo 14-16hr  (433) embryo 16-18hr  (383) embryo 18-20hr  (437) embryo 20-22hr  (464) embryo 22-24hr  (417) larva L1  (334) larva L2  (346) larva L3 12hr old  (397) larva L3 puffstage 1-2  (396) larva L3 puffstage 3-6  (578) larva L3 puffstage 7-9  (660) white prepupae new  (635) white prepupae 12hr  (1048) white prepupae 24hr  (1448) pupae 2d postWPP  (2067) pupae 3d postWPP  (3006) pupae 4d postWPP  (3197) adult male 01day  (5172) adult male 05day  (5958) adult male 30day  (5612) adult female 01day  (1158) adult female 05day  (746) adult female 30day  (776) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    963 embryo 02-04hr    202 embryo 04-06hr    52 embryo 06-08hr    178 embryo 08-10hr    321 embryo 10-12hr    448 embryo 12-14hr    365 embryo 14-16hr    433 embryo 16-18hr    383 embryo 18-20hr    437 embryo 20-22hr    464 embryo 22-24hr    417 larva L1    334 larva L2    346 larva L3 12hr old    397 larva L3 puffstage 1-2    396 larva L3 puffstage 3-6    578 larva L3 puffstage 7-9    660 white prepupae new    635 white prepupae 12hr    1048 white prepupae 24hr  1448 pupae 2d postWPP  (2067) pupae 3d postWPP  (3006) pupae 4d postWPP  (3197) adult male 01day  (5172) adult male 05day  (5958) adult male 30day  (5612) adult female 01day    1158 adult female 05day    746 adult female 30day    776 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    963 embryo 02-04hr    202 embryo 04-06hr    52 embryo 06-08hr    178 embryo 08-10hr    321 embryo 10-12hr    448 embryo 12-14hr    365 embryo 14-16hr    433 embryo 16-18hr    383 embryo 18-20hr    437 embryo 20-22hr    464 embryo 22-24hr    417 larva L1    334 larva L2    346 larva L3 12hr old    397 larva L3 puffstage 1-2    396 larva L3 puffstage 3-6    578 larva L3 puffstage 7-9    660 white prepupae new    635 white prepupae 12hr    1048 white prepupae 24hr    1448 pupae 2d postWPP    2067 pupae 3d postWPP    3006 pupae 4d postWPP    3197 adult male 01day    5172 adult male 05day    5958 adult male 30day    5612 adult female 01day    1158 adult female 05day    746 adult female 30day    776 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    963 embryo 02-04hr    202 embryo 04-06hr    52 embryo 06-08hr    178 embryo 08-10hr    321 embryo 10-12hr    448 embryo 12-14hr    365 embryo 14-16hr    433 embryo 16-18hr    383 embryo 18-20hr    437 embryo 20-22hr    464 embryo 22-24hr    417 larva L1    334 larva L2    346 larva L3 12hr old    397 larva L3 puffstage 1-2    396 larva L3 puffstage 3-6    578 larva L3 puffstage 7-9    660 white prepupae new    635 white prepupae 12hr    1048 white prepupae 24hr    1448 pupae 2d postWPP    2067 pupae 3d postWPP    3006 pupae 4d postWPP    3197 adult male 01day    5172 adult male 05day    5958 adult male 30day    5612 adult female 01day    1158 adult female 05day    746 adult female 30day    776 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0002036 expression level Developmental Stage   Expression Level embryo 00-02hr    963 embryo 02-04hr    202 embryo 04-06hr    52 embryo 06-08hr    178 embryo 08-10hr    321 embryo 10-12hr    448 embryo 12-14hr    365 embryo 14-16hr    433 embryo 16-18hr    383 embryo 18-20hr    437 embryo 20-22hr    464 embryo 22-24hr    417 larva L1    334 larva L2    346 larva L3 12hr old    397 larva L3 puffstage 1-2    396 larva L3 puffstage 3-6    578 larva L3 puffstage 7-9    660 white prepupae new    635 white prepupae 12hr    1048 white prepupae 24hr    1448 pupae 2d postWPP    2067 pupae 3d postWPP    3006 pupae 4d postWPP    3197 adult male 01day    5172 adult male 05day    5958 adult male 30day    5612 adult female 01day    1158 adult female 05day    746 adult female 30day    776 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (963) embryo 02-04hr  (202) embryo 04-06hr    52 embryo 06-08hr  (178) embryo 08-10hr  (321) embryo 10-12hr  (448) embryo 12-14hr  (365) embryo 14-16hr  (433) embryo 16-18hr  (383) embryo 18-20hr  (437) embryo 20-22hr  (464) embryo 22-24hr  (417) larva L1  (334) larva L2  (346) larva L3 12hr old  (397) larva L3 puffstage 1-2  (396) larva L3 puffstage 3-6  (578) larva L3 puffstage 7-9  (660) white prepupae new  (635) white prepupae 12hr  (1048) white prepupae 24hr  (1448) pupae 2d postWPP  (2067) pupae 3d postWPP  (3006) pupae 4d postWPP  (3197) adult male 01day  (5172) adult male 05day  (5958) adult male 30day  (5612) adult female 01day  (1158) adult female 05day  (746) adult female 30day  (776) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    963 embryo 02-04hr    202 embryo 04-06hr    52 embryo 06-08hr    178 embryo 08-10hr    321 embryo 10-12hr    448 embryo 12-14hr    365 embryo 14-16hr    433 embryo 16-18hr    383 embryo 18-20hr    437 embryo 20-22hr    464 embryo 22-24hr    417 larva L1    334 larva L2    346 larva L3 12hr old    397 larva L3 puffstage 1-2    396 larva L3 puffstage 3-6    578 larva L3 puffstage 7-9    660 white prepupae new    635 white prepupae 12hr    1048 white prepupae 24hr  1448 pupae 2d postWPP  2067 pupae 3d postWPP  (3006) pupae 4d postWPP  (3197) adult male 01day  (5172) adult male 05day  (5958) adult male 30day  (5612) adult female 01day    1158 adult female 05day    746 adult female 30day    776 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    963 embryo 02-04hr    202 embryo 04-06hr    52 embryo 06-08hr    178 embryo 08-10hr    321 embryo 10-12hr    448 embryo 12-14hr    365 embryo 14-16hr    433 embryo 16-18hr    383 embryo 18-20hr    437 embryo 20-22hr    464 embryo 22-24hr    417 larva L1    334 larva L2    346 larva L3 12hr old    397 larva L3 puffstage 1-2    396 larva L3 puffstage 3-6    578 larva L3 puffstage 7-9    660 white prepupae new    635 white prepupae 12hr    1048 white prepupae 24hr    1448 pupae 2d postWPP    2067 pupae 3d postWPP    3006 pupae 4d postWPP    3197 adult male 01day    5172 adult male 05day    5958 adult male 30day    5612 adult female 01day    1158 adult female 05day    746 adult female 30day    776 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    963 embryo 02-04hr    202 embryo 04-06hr    52 embryo 06-08hr    178 embryo 08-10hr    321 embryo 10-12hr    448 embryo 12-14hr    365 embryo 14-16hr    433 embryo 16-18hr    383 embryo 18-20hr    437 embryo 20-22hr    464 embryo 22-24hr    417 larva L1    334 larva L2    346 larva L3 12hr old    397 larva L3 puffstage 1-2    396 larva L3 puffstage 3-6    578 larva L3 puffstage 7-9    660 white prepupae new    635 white prepupae 12hr    1048 white prepupae 24hr    1448 pupae 2d postWPP    2067 pupae 3d postWPP    3006 pupae 4d postWPP    3197 adult male 01day    5172 adult male 05day    5958 adult male 30day    5612 adult female 01day    1158 adult female 05day    746 adult female 30day    776 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0002036    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0002036 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, adult hindgut, adult Malpighian tubules, adult heart, larval fat body, adult salivary gland, adult spermathecae, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0002036 expression level Tissue   Expression Level Larval Central Nervous System    71.625 Larval Midgut    64.9 Larval Hindgut    82.6 Larval Malpighian Tubules    61.9 Larval Fat Body    133.5 Larval Salivary Gland    59.6 Larval Trachea    47.5 Larval Carcass    87.85 Adult Head    180.3 Adult Eye    402.65 Adult Brain    266.7 Adult Thoracic-Abdominal Ganglion    373.1 Adult Crop    138.7 Adult Midgut    54.7 Adult Hindgut    145.1 Adult Malpighian Tubules    125 Adult Fat Body    91.7 Adult Salivary Gland    118.9 Adult Heart    107.6 Adult VirginFemale Spermatheca    134.7 Adult InseminatedFemale Spermatheca    131.5 Adult Ovary    97.2 Adult Testis    793.9 Adult Male Accessory Gland    61.1 Adult Carcass    320.2 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    71.625 Larval Midgut    64.9 Larval Hindgut    82.6 Larval Malpighian Tubules    61.9 Larval Fat Body    133.5 Larval Salivary Gland    59.6 Larval Trachea    47.5 Larval Carcass    87.85 Adult Head    180.3 Adult Eye    402.65 Adult Brain    266.7 Adult Thoracic-Abdominal Ganglion    373.1 Adult Crop    138.7 Adult Midgut    54.7 Adult Hindgut    145.1 Adult Malpighian Tubules    125 Adult Fat Body    91.7 Adult Salivary Gland    118.9 Adult Heart    107.6 Adult VirginFemale Spermatheca    134.7 Adult InseminatedFemale Spermatheca    131.5 Adult Ovary    97.2 Adult Testis  (793.9) Adult Male Accessory Gland    61.1 Adult Carcass    320.2 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    71.625 Larval Midgut    64.9 Larval Hindgut    82.6 Larval Malpighian Tubules    61.9 Larval Fat Body    133.5 Larval Salivary Gland    59.6 Larval Trachea    47.5 Larval Carcass    87.85 Adult Head    180.3 Adult Eye    402.65 Adult Brain    266.7 Adult Thoracic-Abdominal Ganglion    373.1 Adult Crop    138.7 Adult Midgut    54.7 Adult Hindgut    145.1 Adult Malpighian Tubules    125 Adult Fat Body    91.7 Adult Salivary Gland    118.9 Adult Heart    107.6 Adult VirginFemale Spermatheca    134.7 Adult InseminatedFemale Spermatheca    131.5 Adult Ovary    97.2 Adult Testis    793.9 Adult Male Accessory Gland    61.1 Adult Carcass    320.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    71.625 Larval Midgut    64.9 Larval Hindgut    82.6 Larval Malpighian Tubules    61.9 Larval Fat Body    133.5 Larval Salivary Gland    59.6 Larval Trachea    47.5 Larval Carcass    87.85 Adult Head    180.3 Adult Eye    402.65 Adult Brain    266.7 Adult Thoracic-Abdominal Ganglion    373.1 Adult Crop    138.7 Adult Midgut    54.7 Adult Hindgut    145.1 Adult Malpighian Tubules    125 Adult Fat Body    91.7 Adult Salivary Gland    118.9 Adult Heart    107.6 Adult VirginFemale Spermatheca    134.7 Adult InseminatedFemale Spermatheca    131.5 Adult Ovary    97.2 Adult Testis    793.9 Adult Male Accessory Gland    61.1 Adult Carcass    320.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0002036 expression level Tissue   Expression Level Larval Central Nervous System    71.625 Larval Midgut    64.9 Larval Hindgut    82.6 Larval Malpighian Tubules    61.9 Larval Fat Body    133.5 Larval Salivary Gland    59.6 Larval Trachea    47.5 Larval Carcass    87.85 Adult Head    180.3 Adult Eye    402.65 Adult Brain    266.7 Adult Thoracic-Abdominal Ganglion    373.1 Adult Crop    138.7 Adult Midgut    54.7 Adult Hindgut    145.1 Adult Malpighian Tubules    125 Adult Fat Body    91.7 Adult Salivary Gland    118.9 Adult Heart    107.6 Adult VirginFemale Spermatheca    134.7 Adult InseminatedFemale Spermatheca    131.5 Adult Ovary    97.2 Adult Testis    793.9 Adult Male Accessory Gland    61.1 Adult Carcass    320.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    71.625 Larval Midgut    64.9 Larval Hindgut    82.6 Larval Malpighian Tubules    61.9 Larval Fat Body    133.5 Larval Salivary Gland    59.6 Larval Trachea    47.5 Larval Carcass    87.85 Adult Head    180.3 Adult Eye    402.65 Adult Brain    266.7 Adult Thoracic-Abdominal Ganglion    373.1 Adult Crop    138.7 Adult Midgut    54.7 Adult Hindgut    145.1 Adult Malpighian Tubules    125 Adult Fat Body    91.7 Adult Salivary Gland    118.9 Adult Heart    107.6 Adult VirginFemale Spermatheca    134.7 Adult InseminatedFemale Spermatheca    131.5 Adult Ovary    97.2 Adult Testis  793.9 Adult Male Accessory Gland    61.1 Adult Carcass    320.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    71.625 Larval Midgut    64.9 Larval Hindgut    82.6 Larval Malpighian Tubules    61.9 Larval Fat Body    133.5 Larval Salivary Gland    59.6 Larval Trachea    47.5 Larval Carcass    87.85 Adult Head    180.3 Adult Eye    402.65 Adult Brain    266.7 Adult Thoracic-Abdominal Ganglion    373.1 Adult Crop    138.7 Adult Midgut    54.7 Adult Hindgut    145.1 Adult Malpighian Tubules    125 Adult Fat Body    91.7 Adult Salivary Gland    118.9 Adult Heart    107.6 Adult VirginFemale Spermatheca    134.7 Adult InseminatedFemale Spermatheca    131.5 Adult Ovary    97.2 Adult Testis    793.9 Adult Male Accessory Gland    61.1 Adult Carcass    320.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    71.625 Larval Midgut    64.9 Larval Hindgut    82.6 Larval Malpighian Tubules    61.9 Larval Fat Body    133.5 Larval Salivary Gland    59.6 Larval Trachea    47.5 Larval Carcass    87.85 Adult Head    180.3 Adult Eye    402.65 Adult Brain    266.7 Adult Thoracic-Abdominal Ganglion    373.1 Adult Crop    138.7 Adult Midgut    54.7 Adult Hindgut    145.1 Adult Malpighian Tubules    125 Adult Fat Body    91.7 Adult Salivary Gland    118.9 Adult Heart    107.6 Adult VirginFemale Spermatheca    134.7 Adult InseminatedFemale Spermatheca    131.5 Adult Ovary    97.2 Adult Testis    793.9 Adult Male Accessory Gland    61.1 Adult Carcass    320.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    180.3   NA  Eye    402.65   NA  Brain    266.7   71.625  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    373.1   NA  Crop    138.7   64.9  Midgut    54.7   82.6  Hindgut    145.1   61.9  Malpighian Tubules    125   133.5  Fat Body    91.7   59.6  Salivary Gland    118.9   NA  Heart    107.6   47.5  Trachea    NA   NA  VirginFemale Spermatheca    134.7   NA  InseminatedFemale Spermatheca    131.5   NA  Ovary    97.2   NA  Testis    793.9   NA  Male Accessory Gland    61.1   87.85  Carcass    320.2 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_00
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0002036 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10561-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG10561 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG10561f06260 viable, with Scer\GAL4pnr-MD237 CG10561GD7017 Sterility Allele fertile CG10561f06260 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG10561 Class Mutagen Stocks Known lesion CG10561f06260 piggyBac transposase 2 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG10561 Class Mutagen Stocks Known lesion CG10561GD7017 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG10561C2 in vitro construct - genomic fragment 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel6042 (Ryder, 2004.4.26) Df(2L)Exel8040 (Ryder, 2004.4.26) Df(2L)TW130 (Black et al., 1987) Df(2L)VA18 (Black et al., 1987)
Not disrupted in	Df(2L)VA17 (Black et al., 1987, Wright, 1996)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7017} NA characterization construct P{pC2} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{WH}CG10561f06260 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
oxidoreductase activity inferred from electronic annotation with InterPro:IPR002937 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
oxidation-reduction process inferred from electronic annotation with InterPro:IPR002937 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
cytoplasm inferred from sequence or structural similarity with UniProtKB:P18487 (assigned by UniProtKB) (Spencer et al., 1986) non-traceable author statement (Swiss-Prot Project Members, 1990.11.1)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG10561 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 61174 DroID - A comprehensive database of gene and protein interactions. • FBgn0002036 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35189
Orthologs
Genome-wide drosophilid orthologs	Dana\GF14703 Dere\GG21160 Dgri\GH13436 Dmoj\GI13981 Dper\GL21188 Dpse\GA10395 Dsec\GM17327 Dsim\GD24185 Dvir\GJ18242 Dwil\GK24793 Dyak\GE13233
Curated drosophilid orthologs	Dleb\CG10561 (Tatarenkov, 1998.9.13) Dpse\GA10395   Dsim\GD24185 (Tatarenkov, 1998.9.13)
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • XP_974097.1 Tribolium castaneum (red flour beetle) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0230926 FBgn0226752 FBgn0205403 FBgn0025651 FBgn0172237 FBgn0070452 FBgn0158781 FBgn0136735 FBgn0120912 FBgn0113342 FBgn0091730
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	18954 w1118; PBac{WH}CG10561f06260
Harvard	- PBac{WH}CG10561f06260
VDRC	v16963 w1118; P{GD7017}v16963
Genomic Clones ( 2 )
	BACR04C20 BACR48O01 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 20 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH22841
Other clones	FI03691
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT03001 AT06155 AT08102 AT14365 AT18284 AT18510 AT19511 AT21185 AT26929 AT27912 AT28642 AT28774 AT29083 AT31717 GH24677
Other clones	bs14b03 bs66b05 EK139701
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0002036 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35189
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG10561 anon-37Cb anon-37Cc (FlyBase, 1996-) Source for merge of: CG10561 anon-37Cd (FlyBase, 1996-)
Additional comments	Source for merge of CG10561 anon-37Cd was sequence comparison (date:050113). (FlyBase, 1996-) Source for merge of CG10561 anon-37Cb anon-37Cc was sequence comparison (date:031111). (FlyBase, 1996-)
Other Comments
	Located between coordinates -1.7 and +0.2. (Stathakis et al., 1995) CG10561 has been cloned and sequenced. The 3' end of the CG10561 gene overlaps with the 3' end of the Ddc gene. (Eveleth and Marsh, 1987) Dot matrix analysis demonstrates there is very little sequence homology between Ddc or amd, and l(2)37Cc or CG10561 transcripts, nor is there any relationship between l(2)37Cc or CG10561 transcripts. (Eveleth and Marsh, 1986)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_057260 RefSeq (Proteins) • NP_476608 DDBJ / EMBL / GenBank • AAC67581 AAF53761 AAL13674 AC005440 AC007176 AF091328 AI403410 AI945547 AW940874 AY058445 CAA29405 CAA29406 CAA29407 CAA29408 X05991 Entrez Gene - A searchable database of RefSeq genes. • 35189 UniProtKB/Swiss-Prot • P18487
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Amine oxidase (IPR002937)
Linkouts
	BioGRID - A database of protein and genetic interactions • 61174 DroID - A comprehensive database of gene and protein interactions. • FBgn0002036 DRSC - Results from RNAi screens. • FBgn0002036 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0002036 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10561-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0002036 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35189 InParanoid A subset of ortholog calls from InParanoid. • XP_974097.1 Tribolium castaneum (red flour beetle) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35189 modMine - Data generated by the modENCODE project. • FBgn0002036 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0230926 FBgn0226752 FBgn0205403 FBgn0025651 FBgn0172237 FBgn0070452 FBgn0158781 FBgn0136735 FBgn0120912 FBgn0113342 FBgn0091730
Synonyms & Secondary IDs ( 19 )
Reported As
Symbol Synonym	anon-37Cb   anon-37Cc   anon-37Cd   anon-37Cs (FlyBase Curators, 2002-) C2 (McCrady and Tolin, 1994) CG10561 (McCrady and Tolin, 1994, Chang et al., 2008) cs (Tatarenkov, 1998.9.13) Cs (Whitfield and Tatarenkov, 1999.4.12, Black et al., 1987) l(2)37Cs (Whitfield and Tatarenkov, 1999.4.12, ) ORF1 (Eveleth, 1999.2.24) ORF2 (Eveleth, 1999.2.24) ORF3 (Eveleth, 1999.2.24) TU37C1   TU37C2 (Wright, 1996, Stathakis et al., 1995) TuC1 (Thor et al., 1999) unnamed (Tatarenkov et al., 1999, Eveleth and Marsh, 1987, Spencer et al., 1986, Eveleth and Marsh, 1986, Spencer et al., 1986)
Name Synonym	lethal(2)37Cs   transcription unit 37C2 (Stathakis et al., 1995) transcription unit No. 2 (Black et al., 1987)
Secondary FlyBase IDs
	FBgn0026744 FBgn0026745 FBgn0043051
References ( 32 )
Generate a list of	All references relating to this gene ( 32 )
List References by type	Research paper  ( 13 ) Supplementary material  ( 3 ) Personal communication to FlyBase  ( 6 ) FlyBase analysis  ( 3 ) DNA/RNA sequence record  ( 4 ) Protein sequence record  ( 1 ) Computer file  ( 1 ) Automatic genome annotation  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2010 Show research papers ...