FB2020_06, released Dec 22, 2020

Gene: Dmel\sas

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General Information
Symbol
Dmel\sas
Species
D. melanogaster
Name
stranded at second
Annotation Symbol
CG2507
Feature Type
protein_coding_gene
FlyBase ID
FBgn0002306
Gene Model Status
Current
Stock Availability
16 publicly available
Gene Snapshot
stranded at second (sas) encodes a single-pass transmembrane protein that localizes to the apical cell surface in polarized epithelia, such as the embryonic/larval salivary gland (SG). Overexpression of sas in the developing SG leads to all membrane domains taking on apical membrane character, with the exception of the region where septate junctions form. [Date last reviewed: 2018-09-13]
Other Summaries
Also Known As

l(3)84Cd, rfd

Key Links
Genomic Location
Cytogenetic map
84C8-84D1
Sequence location
3R:7,162,808..7,183,702 [+]
Recombination map

3-48

RefSeq locus
NT_033777 REGION:7162808..7183702
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (11 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
enables heparin binding
inferred from biological aspect of ancestor with PANTHER:PTN000142748
(assigned by GO_Central )
(Gaudet et al., 2011)
enables integrin binding
inferred from biological aspect of ancestor with PANTHER:PTN000142748
(assigned by GO_Central )
(Gaudet et al., 2011)
enables signaling receptor activity
non-traceable author statement
(assigned by UniProt )
(Schonbaum et al., 1992)
Biological Process (5 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
involved_in axon guidance
inferred from mutant phenotype
(Lee et al., 2013)
involved_in instar larval development
inferred from mutant phenotype
(assigned by UniProt )
(Schonbaum et al., 1992)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
involved_in cell adhesion
inferred from biological aspect of ancestor with PANTHER:PTN000142748
(assigned by GO_Central )
(Gaudet et al., 2011)
involved_in negative regulation of cell death
inferred from biological aspect of ancestor with PANTHER:PTN000142748
(assigned by GO_Central )
(Gaudet et al., 2011)
involved_in signal transduction
inferred from biological aspect of ancestor with PANTHER:PTN000142748
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (3 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
located_in apical plasma membrane
inferred from direct assay
(Firmino et al., 2013)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
located_in apical plasma membrane
non-traceable author statement
(Bachmann et al., 2001)
located_in extracellular matrix
inferred from biological aspect of ancestor with PANTHER:PTN000142748
(assigned by GO_Central )
(Gaudet et al., 2011)
located_in integral component of plasma membrane
non-traceable author statement
(assigned by UniProt )
(Schonbaum et al., 1992)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Protein Function (UniProtKB)
Vital for larval development (PubMed:1339334). During salivary tube elongation, possibly modulates cellular adhesion between the apical surface and apical extracellular matrix, and acts as an apical membrane determinant that functions in apical membrane expansion independently of crb and Cad99C (PubMed:24718992).
(UniProt, Q04164)
Phenotypic Description (Red Book; Lindsley and Zimm 1992)
sas: stranded-at-second (D. R. Cavener)
Homozygous lethal; homozygotes die at the first to second instar molt or at second instar. Larvae do not grow and exhibit a segmentally repeated pattern of tanned spots on the ventral cuticle between the fourth and fifth row of setae and sometimes between the first and second row of setae. Trachae are convoluted.
Summary (Interactive Fly)

Sas and the receptor-type tyrosine phosphatase PTP10D function as the cell-surface ligand-receptor system that drives tumour-suppressive cell competition - trans-activation of Sas-PTP10D signalling in loser cells restrains EGFR signalling cell elimination and thereby enables elevated JNK signalling in loser cells, triggering cell elimination - expression of Sas in neurons and glia and Ptp10D expressed on longitudinal axons are required to prevent axons from abnormally crossing the midline

Gene Model and Products
Number of Transcripts
4
Number of Unique Polypeptides
2

Please see the JBrowse view of Dmel\sas for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.47

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Gene model reviewed during 6.02

Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
sas-RA
FBtr0081571
NM_057263
5115
1348
sas-RB
FBtr0081570
NM_169177
5916
1693
sas-RC
FBtr0334884
NM_001275407
4763
1348
sas-RD
FBtr0334885
NM_001275408
6236
1693
Additional Transcript Data and Comments
Reported size (kB)

5.9, 4.9, 4.0 (northern blot)

(Schonbaum et al., 1992)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
sas-PA
FBpp0081090
147.3
1348
4.36
NP_476611
AAN13346
sas-PB
FBpp0081089
185.3
1693
4.64
NP_731141
AAF54052
sas-PC
FBpp0306905
147.3
1348
4.36
NP_001262336
AGB95719
sas-PD
FBpp0306906
185.3
1693
4.64
NP_001262337
AGB95720
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

1693 aa isoforms: sas-PB, sas-PD
1348 aa isoforms: sas-PA, sas-PC
Additional Polypeptide Data and Comments
Reported size (kDa)

1348 (aa)

(Schonbaum et al., 1992)
Comments
External Data
Domain

The extracellular domain is sufficent for conferring apical characteristics on the salivary gland membrane.

(UniProt, Q04164)
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\sas using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 16
intersegmental nerve root
(Lee et al., 2013)
segmental nerve root
(Lee et al., 2013)
embryonic/larval central nervous system | faint | restricted
(Lee et al., 2013)
embryonic/larval dorsal trunk
(Lee et al., 2013)
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 13
tracheal pit
(Klebes and Knust, 2000)
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in apical plasma membrane
inferred from direct assay
(Firmino et al., 2013)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\sas in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 24 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 13 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of sas
Transgenic constructs containing regulatory region of sas
Deletions and Duplications ( 19 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal, with Scer\GAL4pnr-MD237
lethal | pupal stage, with Scer\GAL4pnr-MD237
lethal | recessive
lethal - all die before end of larval stage
lethal - all die before end of larval stage | cold sensitive
lethal - all die before end of larval stage | recessive
partially lethal - majority die
partially lethal - majority die, with Scer\GAL4pnr-MD237
viable
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
Sterility
Allele
fertile
Other Phenotypes
Allele
cell adhesion defective, with Scer\GAL4fkh.PH
flightless, with Scer\GAL4Mef2.PR
neuroanatomy defective | embryonic stage 16
neuroanatomy defective | embryonic stage 16, with Scer\GAL4elav.PU
neuroanatomy defective | embryonic stage 16, with Scer\GAL4repo.PU
neuroanatomy defective | embryonic stage 16 (with Df(3R)ED5221)
some die during larval stage
some die during larval stage | cold sensitive
some die during larval stage | recessive
Phenotype manifest in
Allele
anterior commissure | embryonic stage 16
anterior commissure | embryonic stage 16 (with Df(3R)ED5221)
embryonic/larval cuticle
embryonic/larval salivary gland, with Scer\GAL4fkh.PH
embryonic/larval trachea
embryonic/larval tracheal system
longitudinal connective | embryonic stage 16
longitudinal connective | embryonic stage 16, with Scer\GAL4elav.PU
longitudinal connective | embryonic stage 16, with Scer\GAL4repo.PU
longitudinal connective | embryonic stage 16 (with Df(3R)ED5221)
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (6)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\CCN1
1 of 15
Yes
No
Hsap\CCN2
1 of 15
Yes
No
2  
Hsap\CCN3
1 of 15
Yes
No
Hsap\CCN4
1 of 15
Yes
No
Hsap\CCN5
1 of 15
Yes
No
Hsap\CCN6
1 of 15
Yes
No
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (6)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Ccn1
1 of 15
Yes
No
Mmus\Ccn2
1 of 15
Yes
No
Mmus\Ccn3
1 of 15
Yes
No
Mmus\Ccn4
1 of 15
Yes
No
Mmus\Ccn5
1 of 15
Yes
No
Mmus\Ccn6
1 of 15
Yes
No
Rattus norvegicus (Norway rat) (6)
Rnor\Ccn1
1 of 13
Yes
No
Rnor\Ccn2
1 of 13
Yes
No
Rnor\Ccn3
1 of 13
Yes
No
Rnor\Ccn4
1 of 13
Yes
No
Rnor\Ccn5
1 of 13
Yes
No
Rnor\Ccn6
1 of 13
Yes
No
Xenopus tropicalis (Western clawed frog) (5)
Xtro\ctgf
1 of 12
Yes
No
Xtro\cyr61
1 of 12
Yes
No
Xtro\nov
1 of 12
Yes
No
Xtro\wisp1
1 of 12
Yes
No
Xtro\wisp2
1 of 12
Yes
No
Danio rerio (Zebrafish) (10)
Drer\ccn1
1 of 15
Yes
No
Drer\ccn1l1
1 of 15
Yes
No
Drer\ccn1l2
1 of 15
Yes
No
Drer\ccn2a
1 of 15
Yes
No
Drer\ccn2b
1 of 15
Yes
No
Drer\ccn4a
1 of 15
Yes
No
Drer\ccn4b
1 of 15
Yes
No
Drer\ccn5
1 of 15
Yes
No
Drer\ccn6
1 of 15
Yes
No
Drer\si:ch211-106h11.3
1 of 15
Yes
No
Caenorhabditis elegans (Nematode, roundworm) (0)
No records found.
Arabidopsis thaliana (thale-cress) (0)
No records found.
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (0)
No records found.
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091901B6 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00009338
Drosophila simulans
Dsim\GD19918
Drosophila sechellia
Dsec\GM10939
Drosophila erecta
Dere\GG13897
Drosophila yakuba
Dyak\GE24910
Drosophila ananassae
Dana\GF17659
Drosophila pseudoobscura pseudoobscura
Dpse\GA27500
Drosophila persimilis
Dper\GL12426
Drosophila willistoni
Dwil\GK14524
Drosophila virilis
Dvir\GJ24577
Drosophila mojavensis
Dmoj\GI23064
Drosophila grimshawi
Dgri\GH19009
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915016G )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17014946
Glossina morsitans
Tsetse fly
Gmor\GMOY003016
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_05568
Mayetiola destructor
Hessian fly
Mdes\Mdes009595
Mayetiola destructor
Hessian fly
Mdes\Mdes005518
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL004214
Anopheles darlingi
American malaria mosquito
Adar\ADAC000758
Anopheles gambiae
Malaria mosquito
Agam\AGAP002579
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ005092
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W01DY )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA005105
Danaus plexippus
Monarch butterfly
Dple\DPOGS204178-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL005752
Apis florea
Little honeybee
Aflo\2565981140
Apis mellifera
Western honey bee
Amel\GB48658
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP13575
Bombus terrestris
Buff-tailed bumblebee
Bter\15216453
Linepithema humile
Argentine ant
Lhum\LH13984
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:0026df
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG003468
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_11335
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_11337
Tribolium castaneum
Red flour beetle
Tcas\TC010099
Pediculus humanus
Human body louse
Phum\PHUM420320
Cimex lectularius
Bed bug
Clec\CLEC002891
Cimex lectularius
Bed bug
Clec\CLEC002892
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI001315
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI085820
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_07711
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X02OO )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR009019
Ixodes scapularis
Black-legged tick
Isca\ISCW013232
Stegodyphus mimosarum
African social velvet spider
Smim\KFM61044.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur14g00440
Tetranychus urticae
Two-spotted spider mite
Turt\tetur70g00050
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( None identified )
No non-Arthropod Metazoa orthologies identified
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (1)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
Ccn
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    esyN Network Diagram
    Show neighbor-neighbor interactions:
    Select Layout:
    Legend:
    Protein
    RNA
    Selected Interactor(s)
    Interactions Browser
    View in Interactions Browser
    Please see the Physical Interaction reports below for full details
    protein-protein
    Physical Interaction
    Assay
    References
    sas - Ptp10D
    affinity technology, tag visualisation, inferred by author, pull down, enzyme linked immunosorbent assay, bead aggregation assay, fluorescence microscopy
    (Lee et al., 2013)
    Summary of Genetic Interactions
    esyN Network Diagram
    esyN Network Key:
    Suppression
    Enhancement
    View in Interactions Browser
    Please look at the allele data for full details of the genetic interactions
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    sas
    enhanceable
    Ptp10D
    (Lee et al., 2013)
    sas
    enhanceable
    Ptp69D
    (Lee et al., 2013)
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    Cad99C
    suppressible
    sas
    (Chung and Andrew, 2014)
    External Data
    Linkouts
    BioGRID - A database of protein and genetic interactions.
    DroID - A comprehensive database of gene and protein interactions.
    InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Pathways
    Signaling Pathways (FlyBase)
    Metabolic Pathways
    External Data
    Linkouts
    Genomic Location and Detailed Mapping Data
    Chromosome (arm)
    3R
    Recombination map

    3-48

    Cytogenetic map
    84C8-84D1
    Sequence location
    3R:7,162,808..7,183,702 [+]
    FlyBase Computed Cytological Location
    Cytogenetic map
    Evidence for location
    84C8-84D1
    Limits computationally determined from genome sequence between P{lacW}l(3)L2100L2100 and P{EP}EP3060EP3060
    Experimentally Determined Cytological Location
    Cytogenetic map
    Notes
    References
    Experimentally Determined Recombination Data
    Location

    3-48

    (FlyBase, 2016)

    3-44.2

    (Comeron et al., 2012)
    Left of (cM)
    Right of (cM)
    Notes
    Stocks and Reagents
    Stocks (16)
    Genomic Clones (27)
    cDNA Clones (16)
     

    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

    cDNA clones, fully sequenced
    BDGP DGC clones
    Other clones
    Drosophila Genomics Resource Center cDNA clones

    For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

    cDNA Clones, End Sequenced (ESTs)
    BDGP DGC clones
    Other clones
    RNAi and Array Information
    Linkouts
    DRSC - Results frm RNAi screens
    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
    Antibody Information
    Laboratory Generated Antibodies
     
    Commercially Available Antibodies
     
    Other Information
    Relationship to Other Genes
    Source for database identify of

    Source for identity of: sas CG2507

    (Milshina, 1999.11)
    Source for database merge of
    Additional comments
    Other Comments

    sas has been cloned and sequenced. RNA expression during development has been determined, and the mutant phenotype analysed.

    (Schonbaum et al., 1992)

    sas gene function is unknown.

    (Cavener et al., 1986)
    Origin and Etymology
    Discoverer
    Etymology
    Identification
    External Crossreferences and Linkouts ( 51 )
    Sequence Crossreferences
    NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
    GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
    GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
    RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
    UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
    UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
    Other crossreferences
    BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
    Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
    Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
    Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
    Flygut - An atlas of the Drosophila adult midgut
    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
    iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
    InterPro - A database of protein families, domains and functional sites
    KEGG Genes - Molecular building blocks of life in the genomic space.
    modMine - A data warehouse for the modENCODE project
    Linkouts
    BioGRID - A database of protein and genetic interactions.
    DroID - A comprehensive database of gene and protein interactions.
    DRSC - Results frm RNAi screens
    FLIGHT - Cell culture data for RNAi and other high-throughput technologies
    FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
    FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
    FlyMine - An integrated database for Drosophila genomics
    Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
    InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Synonyms and Secondary IDs (13)
    Reported As
    Symbol Synonym
    CG2507
    (Hosono et al., 2015, Keleman et al., 2009.8.5)
    SAS
    (Chung and Andrew, 2014, Ismat et al., 2013, Forster et al., 2010, Swaminathan et al., 2010, Chung et al., 2009, Andrew and Baker, 2008, Kerman et al., 2008)
    Sas
    (Fujisawa et al., 2020, Nakajima et al., 2020, Lattner et al., 2019, Enomoto et al., 2018, Richardson and Portela, 2018, Yamamoto et al., 2017, Flores-Benitez and Knust, 2015, Lin et al., 2015, Firmino et al., 2013, Fox et al., 2013, Klose et al., 2013, Lee et al., 2013, Forster et al., 2010, Hamaratoglu et al., 2009, Jeon and Zinn, 2009, Cheshire et al., 2008, Shaye et al., 2008, Lovegrove et al., 2006, Williams et al., 2004, Klebes and Knust, 2000)
    l(3)84Cd
    (Cavener et al., 1986, Cavener et al., 1986)
    rfd
    (Lim and Simmons, 1994, Schneuwly et al., 1987)
    sas
    (Kankel et al., 2020, Coelho and Moreno, 2019, Fahey-Lozano et al., 2019, Ohsawa, 2019, Sarov et al., 2016, Gene Disruption Project members, 2015-, Ashwal-Fluss et al., 2014, Lee et al., 2013, Ozkan et al., 2013, Japanese National Institute of Genetics, 2012.5.21, Davis et al., 2011, Xu et al., 2011, Swaminathan et al., 2010, Christensen et al., 2008.6.11, Buszczak et al., 2007, Gresens and Cook, 2006.12.5, Lindsley and Zimm, 1992)
    Name Synonyms
    Stranded at Second
    (Chung and Andrew, 2014, Chung et al., 2009, Hamaratoglu et al., 2009, Andrew and Baker, 2008, Kerman et al., 2008)
    Stranded at second
    (Lin et al., 2015, Lee et al., 2013, Forster et al., 2010, Swaminathan et al., 2010, Lovegrove et al., 2006, Williams et al., 2004)
    Stranded-at-second
    (Shaye et al., 2008)
    responsible for dominant phenotype
    (Schneuwly et al., 1987)
    stranded at Second
    (Jeon and Zinn, 2009)
    stranded at second
    (Campbell et al., 2019, Davis et al., 2011)
    stranded-at-second
    (Lindsley and Zimm, 1992)
    Secondary FlyBase IDs
      Datasets (0)
      Study focus (0)
      Experimental Role
      Project
      Project Type
      Title
      References (93)