AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Apparent introns not annotated: probable artifact due to repetitive sequence.
Gene model reviewed during 5.46
Low-frequency RNA-Seq exon junction(s) not annotated.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Lcp4 using the Feature Mapper tool.
Lcp4 transript is expressed at highest levels during the synthesis of the third instar larval cuticle, but is also detected at significant levels in first and second instar larvae, and in wandering third instar larvae. Lcp4 transcript is detected in pupae, up to 7-13 hours after pupariation.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Lcp4 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
In a sample of 79 genes with multiple introns, 33 showed significant heterogeneity in G+C content among introns of the same gene and significant positive correspondence between the intron and the third codon position G+C content within genes. These results are consistent with selection adding against preferred codons at the start of genes.
One of a series of genes encoding electrophoretically separable proteins extractable from the cuticles of third instar larvae, but not other stages. Four immunologically related proteins are encoded by a cluster of genes on 2R and another cluster of three unrelated to the preceding four, but related to each other, located on 3L. Lcp4 encodes larval cuticle protein CP4 (alternatively L3CP4); molecular weight 13kD. Has a 15-residue signal peptide.