Vps41, l(2)40Fb
Please see the JBrowse view of Dmel\lt for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.53
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.46
Low-frequency RNA-Seq exon junction(s) not annotated.
Evidence supports alternative transcription start site within flanking TE (RAMPAGE TSS data, FBrf0220331; RNA-Seq junction data). May be specific to sequenced strain; not included in gene model.
Gene model reviewed during 5.55
3.3, 3.0 (northern blot)
3.6, 3.2 (northern blot)
841 (aa)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\lt using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signals
View Dmel\lt in GBrowse 2Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: lt CG18028
'Light mottled' lt alleles are a series of X-ray induced light-variegated chromosome rearrangements. Some have a mixture of light and wild-type ommatidia and are classified as pale; others have a mixture of wild-type and occasional darker ommatidia and are classified as dark.
Variegation of lt and cta is manifest at phenotypic and gene expression levels in the adult eye, and the larval salivary glands and Malpighian tubules. The relative severity of the effect correlates with the chromosomal rearrangement. Larval imaginal discs do not display variegation, but show uniform reduction of transcription, which correlates in magnitude with the degree of variegation.
Mapping and complementation data of Class IV derivatives of the T(2;3)ltX13, P{wF} chromosome suggest that the amount of heterochromatin in cis to the lt gene is correlated with its level of activity. Chromosomes that carry the smallest deletion of heterochromatin have weaker effects on the lt+ gene when compared to those with the largest deletions.
Lesions in lt reduce or eliminate pigmentation in the eyes and ocelli and block pigmentation of the fat body and tubules: lt is required for normal pigmentation of all four tissues.