ltd, lightoid, Rab-RP1, DmRab32, RabRP1
Please see the JBrowse view of Dmel\Rab32 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.49
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.57
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Rab32 using the Feature Mapper tool.
Comment: maternally deposited
Comment: rapidly degraded
Isoform-specific expression patterns are observed. Sex-specific expression of alternative transcripts observed.
Eye-enriched transcripts determined by ratio of expression level in wild-type heads. versus expression level in so heads.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Rab32 in GBrowse 2Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Rab32 ltd
Source for merge of: ltd Rab-RP1
Source for merge of: ltd anon-WO0118547.106
Renamed from 'ltd' to 'Rab32' (a popular synonym) to be consistent with the nomenclature of all other Rab genes.
Source for merge of ltd anon-WO0118547.106 was sequence comparison ( date:051113 ).
dsRNA has been made from templates generated with primers directed against this gene.
Shows particularly robust cycling of transcription in adult heads, as assessed by expression analysis using high density oligonucleotide arrays with probe generated during three 12-point time course experiments over the course of 6 days. Shows significant change of expression pattern in circadian mutant background; decreased expression in per01, tim01 and ClkJrk background.
Area matching Drosophila EST AA979014.
Used as a marker gene, results of LUG and SIP analysis shows genes conferring resistance to parasitism by A.tabida are restricted to the second chromosome.
ltd is required for the synthesis of ommochrome in any tissue and may be a component of the ommochrome precursor transport system.
Lesions in ltd reduce or eliminate pigmentation in the eyes and ocelli and block pigmentation of the fat body and tubules.
Pteridines (neodrosopterin, drosopterin, isodrosopterin, aurodrosopterin, 6-acetyl-dihydrohomopterin, sepiapterin, dihydrobiopterin, biopterin, pterin and isoxanthopterin) have been quantified in single and double mutants.
It is likely that this gene is required for the normal transport of eye-pigment precursors.
Nichols-Skoog, 6th April 1936.
Given the name "beck", after one of Pavlov's dogs.