LvpH, mal_A1, H, Larval visceral protein H
Gene model reviewed during 5.49
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Mal-A1 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Mal-A1 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Mal-A1 LvpH
One of three genes that are clustered in an 8 kb segment of DNA and lie 11 kb from the second-chromosome Lcp gene cluster (Snyder and Davidson, 1983). The order of the genes is LvpH--1.7kb--LvpD--1.1kb--LvpL, with LvpH being closest to the Lcp cluster. LvpH and LvpL are transcribed off the same strand as Lcp1 and Lcp2 and LcpD off the same strand as Lcp3 and Lcp4. Three genes are completely sequenced and are 50-60% homologous in DNA sequence; they encode polypeptides of approximately 500 amino acids, which contain apparent signal peptide sequences but lack hydrophobic regions indicating that they are secreted rather than being membrane proteins; each has a sequence of 12 amino acids similar to known calcium binding domains of other proteins. The genes are coordinately transcribed in abundance in young larvae and adults, but not in late larvae when Lcp genes are transcribed; whereas Lcp genes are transcribed in the larval cuticle, Lvp transcripts are found in the larval viscera. The time and place of Lvp transcription suggests a possible digestive function of the gene products.