General Information Symbol Dmel\ RpL19Species D. melanogaster Name Ribosomal protein L19 Annotation symbol CG2746 Feature type protein_coding_gene FlyBase ID FBgn0002607 Gene Model Status Current Stock availability 3 publicly
available Also Known As l(2)k03704, M(2)60E, M(2)c, E(Dl)KP135, L19 Genomic Location Chromosome (arm) 2R Recombination map 2-108 Cytogenetic map 60E11-60E11 Sequence location 2R:20,855,968..20,857,070 [-]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information The gene
Ribosomal protein L19 is referred to in FlyBase by the symbol
Dmel\RpL19 (CG2746, FBgn0002607). It is a protein_coding_gene from
Drosophila melanogaster . There is experimental evidence that it has the
molecular function : structural constituent of ribosome. There is experimental evidence that it is involved in the
biological process : mitotic spindle elongation; centrosome duplication.
16 alleles are reported . The
phenotype of these alleles is annotated with: macrochaeta. It has
2 annotated transcripts and
2 annotated polypeptides .
Protein features are: Ribosomal protein L19/L19e; Ribosomal protein L19/L19e conserved site; Ribosomal protein L19/L19e, domain 1; Ribosomal protein L19/L19e, domain 3. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1630455_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of RpL19. Gene sequence location is
2R:20855968..20857070 .
User Contributed Data
Phenotypic Description from the Red Book (Lindsley
& Zimm 1992) Gene/Allele symbols may differ
from current usage M(2)60E
Fairly strong Minute; slow development; good viability and fertility [description based on Df(2R)M60E =
Df(2R)60E2-3;60E11-12]. Eclosion of Df(2R)M60E/+ delayed 49
hours (Ferrus, 1975, Genetics 79: 589-99).
Recent Updates
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FB2013_03
FB2013_02
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
60E8-60E9
(determined by in situ hybridisation)
60E9-60E12
(determined by in situ hybridisation)
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: maternally deposited
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) inferred from direct assay
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
2762.05
Larval Midgut
5279.4
Larval Hindgut
4624.5
Larval Malpighian Tubules
5489.1
Larval Fat Body
7944.6
Larval Salivary Gland
7466
Larval Trachea
6452.7
Larval Carcass
5023.1
Adult Head
4804.6
Adult Eye
6851.925
Adult Brain
2896.9
Adult Thoracic-Abdominal Ganglion
4031.6
Adult Crop
6533.5
Adult Midgut
5472.5
Adult Hindgut
5154.9
Adult Malpighian Tubules
5695.7
Adult Fat Body
5901.9
Adult Salivary Gland
10615.8
Adult Heart
7115.475
Adult VirginFemale Spermatheca
5061.8
Adult InseminatedFemale Spermatheca
5206.2
Adult Ovary
3677.5
Adult Testis
1404
Adult Male Accessory Gland
9263.1
Adult Carcass
6003.6
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
(2762.05)
Larval Midgut
(5279.4)
Larval Hindgut
(4624.5)
Larval Malpighian Tubules
(5489.1)
Larval Fat Body
(7944.6)
Larval Salivary Gland
(7466)
Larval Trachea
(6452.7)
Larval Carcass
(5023.1)
Adult Head
(4804.6)
Adult Eye
(6851.925)
Adult Brain
(2896.9)
Adult Thoracic-Abdominal Ganglion
(4031.6)
Adult Crop
(6533.5)
Adult Midgut
(5472.5)
Adult Hindgut
(5154.9)
Adult Malpighian Tubules
(5695.7)
Adult Fat Body
(5901.9)
Adult Salivary Gland
(10615.8)
Adult Heart
(7115.475)
Adult VirginFemale Spermatheca
(5061.8)
Adult InseminatedFemale Spermatheca
(5206.2)
Adult Ovary
(3677.5)
Adult Testis
(1404)
Adult Male Accessory Gland
(9263.1)
Adult Carcass
(6003.6)
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
(2762.05)
Larval Midgut
(5279.4)
Larval Hindgut
(4624.5)
Larval Malpighian Tubules
(5489.1)
Larval Fat Body
(7944.6)
Larval Salivary Gland
(7466)
Larval Trachea
(6452.7)
Larval Carcass
(5023.1)
Adult Head
(4804.6)
Adult Eye
(6851.925)
Adult Brain
(2896.9)
Adult Thoracic-Abdominal Ganglion
(4031.6)
Adult Crop
(6533.5)
Adult Midgut
(5472.5)
Adult Hindgut
(5154.9)
Adult Malpighian Tubules
(5695.7)
Adult Fat Body
(5901.9)
Adult Salivary Gland
(10615.8)
Adult Heart
(7115.475)
Adult VirginFemale Spermatheca
(5061.8)
Adult InseminatedFemale Spermatheca
(5206.2)
Adult Ovary
(3677.5)
Adult Testis
(1404)
Adult Male Accessory Gland
(9263.1)
Adult Carcass
(6003.6)
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
2762.05
Larval Midgut
5279.4
Larval Hindgut
4624.5
Larval Malpighian Tubules
5489.1
Larval Fat Body
7944.6
Larval Salivary Gland
7466
Larval Trachea
6452.7
Larval Carcass
5023.1
Adult Head
4804.6
Adult Eye
6851.925
Adult Brain
2896.9
Adult Thoracic-Abdominal Ganglion
4031.6
Adult Crop
6533.5
Adult Midgut
5472.5
Adult Hindgut
5154.9
Adult Malpighian Tubules
5695.7
Adult Fat Body
5901.9
Adult Salivary Gland
10615.8
Adult Heart
7115.475
Adult VirginFemale Spermatheca
5061.8
Adult InseminatedFemale Spermatheca
5206.2
Adult Ovary
3677.5
Adult Testis
1404
Adult Male Accessory Gland
9263.1
Adult Carcass
6003.6
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
2762.05
Larval Midgut
5279.4
Larval Hindgut
4624.5
Larval Malpighian Tubules
5489.1
Larval Fat Body
7944.6
Larval Salivary Gland
7466
Larval Trachea
6452.7
Larval Carcass
5023.1
Adult Head
4804.6
Adult Eye
6851.925
Adult Brain
2896.9
Adult Thoracic-Abdominal Ganglion
4031.6
Adult Crop
6533.5
Adult Midgut
5472.5
Adult Hindgut
5154.9
Adult Malpighian Tubules
5695.7
Adult Fat Body
5901.9
Adult Salivary Gland
10615.8
Adult Heart
7115.475
Adult VirginFemale Spermatheca
5061.8
Adult InseminatedFemale Spermatheca
5206.2
Adult Ovary
3677.5
Adult Testis
1404
Adult Male Accessory Gland
9263.1
Adult Carcass
6003.6
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
(2762.05)
Larval Midgut
(5279.4)
Larval Hindgut
(4624.5)
Larval Malpighian Tubules
(5489.1)
Larval Fat Body
(7944.6)
Larval Salivary Gland
(7466)
Larval Trachea
(6452.7)
Larval Carcass
(5023.1)
Adult Head
(4804.6)
Adult Eye
(6851.925)
Adult Brain
(2896.9)
Adult Thoracic-Abdominal Ganglion
(4031.6)
Adult Crop
(6533.5)
Adult Midgut
(5472.5)
Adult Hindgut
(5154.9)
Adult Malpighian Tubules
(5695.7)
Adult Fat Body
(5901.9)
Adult Salivary Gland
(10615.8)
Adult Heart
(7115.475)
Adult VirginFemale Spermatheca
(5061.8)
Adult InseminatedFemale Spermatheca
(5206.2)
Adult Ovary
(3677.5)
Adult Testis
(1404)
Adult Male Accessory Gland
(9263.1)
Adult Carcass
(6003.6)
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
(2762.05)
Larval Midgut
(5279.4)
Larval Hindgut
(4624.5)
Larval Malpighian Tubules
(5489.1)
Larval Fat Body
(7944.6)
Larval Salivary Gland
(7466)
Larval Trachea
(6452.7)
Larval Carcass
(5023.1)
Adult Head
(4804.6)
Adult Eye
(6851.925)
Adult Brain
(2896.9)
Adult Thoracic-Abdominal Ganglion
(4031.6)
Adult Crop
(6533.5)
Adult Midgut
(5472.5)
Adult Hindgut
(5154.9)
Adult Malpighian Tubules
(5695.7)
Adult Fat Body
(5901.9)
Adult Salivary Gland
(10615.8)
Adult Heart
(7115.475)
Adult VirginFemale Spermatheca
(5061.8)
Adult InseminatedFemale Spermatheca
(5206.2)
Adult Ovary
(3677.5)
Adult Testis
1404
Adult Male Accessory Gland
(9263.1)
Adult Carcass
(6003.6)
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
2762.05
Larval Midgut
5279.4
Larval Hindgut
4624.5
Larval Malpighian Tubules
5489.1
Larval Fat Body
7944.6
Larval Salivary Gland
7466
Larval Trachea
6452.7
Larval Carcass
5023.1
Adult Head
4804.6
Adult Eye
6851.925
Adult Brain
2896.9
Adult Thoracic-Abdominal Ganglion
4031.6
Adult Crop
6533.5
Adult Midgut
5472.5
Adult Hindgut
5154.9
Adult Malpighian Tubules
5695.7
Adult Fat Body
5901.9
Adult Salivary Gland
10615.8
Adult Heart
7115.475
Adult VirginFemale Spermatheca
5061.8
Adult InseminatedFemale Spermatheca
5206.2
Adult Ovary
3677.5
Adult Testis
1404
Adult Male Accessory Gland
9263.1
Adult Carcass
6003.6
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
4804.6
NA
Eye
6851.925
NA
Brain
2896.9
2762.05
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
4031.6
NA
Crop
6533.5
5279.4
Midgut
5472.5
4624.5
Hindgut
5154.9
5489.1
Malpighian Tubules
5695.7
7944.6
Fat Body
5901.9
7466
Salivary Gland
10615.8
NA
Heart
7115.475
6452.7
Trachea
NA
NA
VirginFemale Spermatheca
5061.8
NA
InseminatedFemale Spermatheca
5206.2
NA
Ovary
3677.5
NA
Testis
1404
NA
Male Accessory Gland
9263.1
5023.1
Carcass
6003.6
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
1460
central nervous system, larvae L3
1039
central nervous system, pupae P8
414
head, virgin 1-day female
609
head, virgin 4-day female
964
head, virgin 20-day female
1045
head, mated 1-day female
603
head, mated 4-day female
783
head, mated 20-day female
909
head, mated 1-day male
582
head, mated 4-day male
538
head, mated 20-day male
719
salivary gland, larvae L3 wandering
636
salivary gland, white prepupae
1291
digestive system, larvae L3 wandering
1043
digestive system, 1-day adult
790
digestive system, 4-day adult
708
digestive system, 20-day adult
786
fat body, larvae L3 wandering
921
fat body, white prepupae
572
fat body, pupae P8
1274
carcass, larvae L3 wandering
1134
carcass, 1-day adult
611
carcass, 4-day adult
767
carcass, 20-day adult
1027
ovary, virgin 4-day female
1072
ovary, mated 4-day female
1046
testis, mated 4-day male
508
accessory gland, mated 4-day male
959
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(1460)
central nervous system, larvae L3
(1039)
central nervous system, pupae P8
(414)
head, virgin 1-day female
(609)
head, virgin 4-day female
(964)
head, virgin 20-day female
(1045)
head, mated 1-day female
(603)
head, mated 4-day female
(783)
head, mated 20-day female
(909)
head, mated 1-day male
(582)
head, mated 4-day male
(538)
head, mated 20-day male
(719)
salivary gland, larvae L3 wandering
(636)
salivary gland, white prepupae
(1291)
digestive system, larvae L3 wandering
(1043)
digestive system, 1-day adult
(790)
digestive system, 4-day adult
(708)
digestive system, 20-day adult
(786)
fat body, larvae L3 wandering
(921)
fat body, white prepupae
(572)
fat body, pupae P8
(1274)
carcass, larvae L3 wandering
(1134)
carcass, 1-day adult
(611)
carcass, 4-day adult
(767)
carcass, 20-day adult
(1027)
ovary, virgin 4-day female
(1072)
ovary, mated 4-day female
(1046)
testis, mated 4-day male
(508)
accessory gland, mated 4-day male
(959)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(1460)
central nervous system, larvae L3
(1039)
central nervous system, pupae P8
(414)
head, virgin 1-day female
(609)
head, virgin 4-day female
(964)
head, virgin 20-day female
(1045)
head, mated 1-day female
(603)
head, mated 4-day female
(783)
head, mated 20-day female
(909)
head, mated 1-day male
(582)
head, mated 4-day male
(538)
head, mated 20-day male
(719)
salivary gland, larvae L3 wandering
(636)
salivary gland, white prepupae
(1291)
digestive system, larvae L3 wandering
(1043)
digestive system, 1-day adult
(790)
digestive system, 4-day adult
(708)
digestive system, 20-day adult
(786)
fat body, larvae L3 wandering
(921)
fat body, white prepupae
(572)
fat body, pupae P8
(1274)
carcass, larvae L3 wandering
(1134)
carcass, 1-day adult
(611)
carcass, 4-day adult
(767)
carcass, 20-day adult
(1027)
ovary, virgin 4-day female
(1072)
ovary, mated 4-day female
(1046)
testis, mated 4-day male
(508)
accessory gland, mated 4-day male
(959)
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
1460
central nervous system, larvae L3
1039
central nervous system, pupae P8
414
head, virgin 1-day female
609
head, virgin 4-day female
964
head, virgin 20-day female
1045
head, mated 1-day female
603
head, mated 4-day female
783
head, mated 20-day female
909
head, mated 1-day male
582
head, mated 4-day male
538
head, mated 20-day male
719
salivary gland, larvae L3 wandering
636
salivary gland, white prepupae
1291
digestive system, larvae L3 wandering
1043
digestive system, 1-day adult
790
digestive system, 4-day adult
708
digestive system, 20-day adult
786
fat body, larvae L3 wandering
921
fat body, white prepupae
572
fat body, pupae P8
1274
carcass, larvae L3 wandering
1134
carcass, 1-day adult
611
carcass, 4-day adult
767
carcass, 20-day adult
1027
ovary, virgin 4-day female
1072
ovary, mated 4-day female
1046
testis, mated 4-day male
508
accessory gland, mated 4-day male
959
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
1460
central nervous system, larvae L3
1039
central nervous system, pupae P8
414
head, virgin 1-day female
609
head, virgin 4-day female
964
head, virgin 20-day female
1045
head, mated 1-day female
603
head, mated 4-day female
783
head, mated 20-day female
909
head, mated 1-day male
582
head, mated 4-day male
538
head, mated 20-day male
719
salivary gland, larvae L3 wandering
636
salivary gland, white prepupae
1291
digestive system, larvae L3 wandering
1043
digestive system, 1-day adult
790
digestive system, 4-day adult
708
digestive system, 20-day adult
786
fat body, larvae L3 wandering
921
fat body, white prepupae
572
fat body, pupae P8
1274
carcass, larvae L3 wandering
1134
carcass, 1-day adult
611
carcass, 4-day adult
767
carcass, 20-day adult
1027
ovary, virgin 4-day female
1072
ovary, mated 4-day female
1046
testis, mated 4-day male
508
accessory gland, mated 4-day male
959
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(1460)
central nervous system, larvae L3
(1039)
central nervous system, pupae P8
(414)
head, virgin 1-day female
(609)
head, virgin 4-day female
(964)
head, virgin 20-day female
(1045)
head, mated 1-day female
(603)
head, mated 4-day female
(783)
head, mated 20-day female
(909)
head, mated 1-day male
(582)
head, mated 4-day male
(538)
head, mated 20-day male
(719)
salivary gland, larvae L3 wandering
(636)
salivary gland, white prepupae
(1291)
digestive system, larvae L3 wandering
(1043)
digestive system, 1-day adult
(790)
digestive system, 4-day adult
(708)
digestive system, 20-day adult
(786)
fat body, larvae L3 wandering
(921)
fat body, white prepupae
(572)
fat body, pupae P8
(1274)
carcass, larvae L3 wandering
(1134)
carcass, 1-day adult
(611)
carcass, 4-day adult
(767)
carcass, 20-day adult
(1027)
ovary, virgin 4-day female
(1072)
ovary, mated 4-day female
(1046)
testis, mated 4-day male
(508)
accessory gland, mated 4-day male
(959)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(1460)
central nervous system, larvae L3
(1039)
central nervous system, pupae P8
(414)
head, virgin 1-day female
(609)
head, virgin 4-day female
(964)
head, virgin 20-day female
(1045)
head, mated 1-day female
(603)
head, mated 4-day female
(783)
head, mated 20-day female
(909)
head, mated 1-day male
(582)
head, mated 4-day male
(538)
head, mated 20-day male
(719)
salivary gland, larvae L3 wandering
(636)
salivary gland, white prepupae
(1291)
digestive system, larvae L3 wandering
(1043)
digestive system, 1-day adult
(790)
digestive system, 4-day adult
(708)
digestive system, 20-day adult
(786)
fat body, larvae L3 wandering
(921)
fat body, white prepupae
(572)
fat body, pupae P8
(1274)
carcass, larvae L3 wandering
(1134)
carcass, 1-day adult
(611)
carcass, 4-day adult
(767)
carcass, 20-day adult
(1027)
ovary, virgin 4-day female
(1072)
ovary, mated 4-day female
(1046)
testis, mated 4-day male
(508)
accessory gland, mated 4-day male
(959)
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
1460
central nervous system, larvae L3
1039
central nervous system, pupae P8
414
head, virgin 1-day female
609
head, virgin 4-day female
964
head, virgin 20-day female
1045
head, mated 1-day female
603
head, mated 4-day female
783
head, mated 20-day female
909
head, mated 1-day male
582
head, mated 4-day male
538
head, mated 20-day male
719
salivary gland, larvae L3 wandering
636
salivary gland, white prepupae
1291
digestive system, larvae L3 wandering
1043
digestive system, 1-day adult
790
digestive system, 4-day adult
708
digestive system, 20-day adult
786
fat body, larvae L3 wandering
921
fat body, white prepupae
572
fat body, pupae P8
1274
carcass, larvae L3 wandering
1134
carcass, 1-day adult
611
carcass, 4-day adult
767
carcass, 20-day adult
1027
ovary, virgin 4-day female
1072
ovary, mated 4-day female
1046
testis, mated 4-day male
508
accessory gland, mated 4-day male
959
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
2485
embryo 02-04hr
3366
embryo 04-06hr
3188
embryo 06-08hr
3480
embryo 08-10hr
3668
embryo 10-12hr
4475
embryo 12-14hr
2872
embryo 14-16hr
3021
embryo 16-18hr
3122
embryo 18-20hr
3472
embryo 20-22hr
3140
embryo 22-24hr
2899
larva L1
3985
larva L2
3231
larva L3 12hr old
2633
larva L3 puffstage 1-2
2280
larva L3 puffstage 3-6
2258
larva L3 puffstage 7-9
2244
white prepupae new
2025
white prepupae 12hr
1743
white prepupae 24hr
1763
pupae 2d postWPP
1691
pupae 3d postWPP
1318
pupae 4d postWPP
1426
adult male 01day
1140
adult male 05day
1236
adult male 30day
1369
adult female 01day
2655
adult female 05day
2557
adult female 30day
2802
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(2485)
embryo 02-04hr
(3366)
embryo 04-06hr
(3188)
embryo 06-08hr
(3480)
embryo 08-10hr
(3668)
embryo 10-12hr
(4475)
embryo 12-14hr
(2872)
embryo 14-16hr
(3021)
embryo 16-18hr
(3122)
embryo 18-20hr
(3472)
embryo 20-22hr
(3140)
embryo 22-24hr
(2899)
larva L1
(3985)
larva L2
(3231)
larva L3 12hr old
(2633)
larva L3 puffstage 1-2
(2280)
larva L3 puffstage 3-6
(2258)
larva L3 puffstage 7-9
(2244)
white prepupae new
(2025)
white prepupae 12hr
(1743)
white prepupae 24hr
(1763)
pupae 2d postWPP
(1691)
pupae 3d postWPP
(1318)
pupae 4d postWPP
(1426)
adult male 01day
(1140)
adult male 05day
(1236)
adult male 30day
(1369)
adult female 01day
(2655)
adult female 05day
(2557)
adult female 30day
(2802)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
(2485)
embryo 02-04hr
(3366)
embryo 04-06hr
(3188)
embryo 06-08hr
(3480)
embryo 08-10hr
(3668)
embryo 10-12hr
(4475)
embryo 12-14hr
(2872)
embryo 14-16hr
(3021)
embryo 16-18hr
(3122)
embryo 18-20hr
(3472)
embryo 20-22hr
(3140)
embryo 22-24hr
(2899)
larva L1
(3985)
larva L2
(3231)
larva L3 12hr old
(2633)
larva L3 puffstage 1-2
(2280)
larva L3 puffstage 3-6
(2258)
larva L3 puffstage 7-9
(2244)
white prepupae new
(2025)
white prepupae 12hr
(1743)
white prepupae 24hr
(1763)
pupae 2d postWPP
(1691)
pupae 3d postWPP
(1318)
pupae 4d postWPP
(1426)
adult male 01day
(1140)
adult male 05day
(1236)
adult male 30day
(1369)
adult female 01day
(2655)
adult female 05day
(2557)
adult female 30day
(2802)
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
2485
embryo 02-04hr
3366
embryo 04-06hr
3188
embryo 06-08hr
3480
embryo 08-10hr
3668
embryo 10-12hr
4475
embryo 12-14hr
2872
embryo 14-16hr
3021
embryo 16-18hr
3122
embryo 18-20hr
3472
embryo 20-22hr
3140
embryo 22-24hr
2899
larva L1
3985
larva L2
3231
larva L3 12hr old
2633
larva L3 puffstage 1-2
2280
larva L3 puffstage 3-6
2258
larva L3 puffstage 7-9
2244
white prepupae new
2025
white prepupae 12hr
1743
white prepupae 24hr
1763
pupae 2d postWPP
1691
pupae 3d postWPP
1318
pupae 4d postWPP
1426
adult male 01day
1140
adult male 05day
1236
adult male 30day
1369
adult female 01day
2655
adult female 05day
2557
adult female 30day
2802
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
2485
embryo 02-04hr
3366
embryo 04-06hr
3188
embryo 06-08hr
3480
embryo 08-10hr
3668
embryo 10-12hr
4475
embryo 12-14hr
2872
embryo 14-16hr
3021
embryo 16-18hr
3122
embryo 18-20hr
3472
embryo 20-22hr
3140
embryo 22-24hr
2899
larva L1
3985
larva L2
3231
larva L3 12hr old
2633
larva L3 puffstage 1-2
2280
larva L3 puffstage 3-6
2258
larva L3 puffstage 7-9
2244
white prepupae new
2025
white prepupae 12hr
1743
white prepupae 24hr
1763
pupae 2d postWPP
1691
pupae 3d postWPP
1318
pupae 4d postWPP
1426
adult male 01day
1140
adult male 05day
1236
adult male 30day
1369
adult female 01day
2655
adult female 05day
2557
adult female 30day
2802
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(2485)
embryo 02-04hr
(3366)
embryo 04-06hr
(3188)
embryo 06-08hr
(3480)
embryo 08-10hr
(3668)
embryo 10-12hr
(4475)
embryo 12-14hr
(2872)
embryo 14-16hr
(3021)
embryo 16-18hr
(3122)
embryo 18-20hr
(3472)
embryo 20-22hr
(3140)
embryo 22-24hr
(2899)
larva L1
(3985)
larva L2
(3231)
larva L3 12hr old
(2633)
larva L3 puffstage 1-2
(2280)
larva L3 puffstage 3-6
(2258)
larva L3 puffstage 7-9
(2244)
white prepupae new
(2025)
white prepupae 12hr
(1743)
white prepupae 24hr
(1763)
pupae 2d postWPP
(1691)
pupae 3d postWPP
(1318)
pupae 4d postWPP
(1426)
adult male 01day
(1140)
adult male 05day
(1236)
adult male 30day
(1369)
adult female 01day
(2655)
adult female 05day
(2557)
adult female 30day
(2802)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
(2485)
embryo 02-04hr
(3366)
embryo 04-06hr
(3188)
embryo 06-08hr
(3480)
embryo 08-10hr
(3668)
embryo 10-12hr
(4475)
embryo 12-14hr
(2872)
embryo 14-16hr
(3021)
embryo 16-18hr
(3122)
embryo 18-20hr
(3472)
embryo 20-22hr
(3140)
embryo 22-24hr
(2899)
larva L1
(3985)
larva L2
(3231)
larva L3 12hr old
(2633)
larva L3 puffstage 1-2
(2280)
larva L3 puffstage 3-6
(2258)
larva L3 puffstage 7-9
(2244)
white prepupae new
(2025)
white prepupae 12hr
(1743)
white prepupae 24hr
(1763)
pupae 2d postWPP
(1691)
pupae 3d postWPP
(1318)
pupae 4d postWPP
(1426)
adult male 01day
(1140)
adult male 05day
(1236)
adult male 30day
(1369)
adult female 01day
(2655)
adult female 05day
(2557)
adult female 30day
(2802)
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
2485
embryo 02-04hr
3366
embryo 04-06hr
3188
embryo 06-08hr
3480
embryo 08-10hr
3668
embryo 10-12hr
4475
embryo 12-14hr
2872
embryo 14-16hr
3021
embryo 16-18hr
3122
embryo 18-20hr
3472
embryo 20-22hr
3140
embryo 22-24hr
2899
larva L1
3985
larva L2
3231
larva L3 12hr old
2633
larva L3 puffstage 1-2
2280
larva L3 puffstage 3-6
2258
larva L3 puffstage 7-9
2244
white prepupae new
2025
white prepupae 12hr
1743
white prepupae 24hr
1763
pupae 2d postWPP
1691
pupae 3d postWPP
1318
pupae 4d postWPP
1426
adult male 01day
1140
adult male 05day
1236
adult male 30day
1369
adult female 01day
2655
adult female 05day
2557
adult female 30day
2802
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
1803
Schneider line 2 Sg4
1450
embryonic 1182-4H
2037
embryonic GM2
1301
embryonic Kc167
1169
embryonic S1
946
embryonic S3
1228
leg disc CME L1
2254
wing disc CME-W2
1510
wing disc ML-DmD8
2109
wing disc ML-DmD9
1978
wing disc ML-DmD16-c3
1729
wing disc ML-DmD21
3310
wing disc ML-DmD32
1455
haltere disc ML-DmD17-c3
1183
eye-antennal disc ML-DmD11
3003
antennal disc ML-DmD20-c5
2075
mixed discs ML-DmD4-c1
2271
CNS ML-DmBG1-c1
2133
CNS ML-DmBG2-c2
1335
tumorous blood cells mbn2
967
ovary fGS/OSS
1111
ovary OSC
944
ovary OSS
424
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(1803)
Schneider line 2 Sg4
(1450)
embryonic 1182-4H
(2037)
embryonic GM2
(1301)
embryonic Kc167
(1169)
embryonic S1
(946)
embryonic S3
(1228)
leg disc CME L1
(2254)
wing disc CME-W2
(1510)
wing disc ML-DmD8
(2109)
wing disc ML-DmD9
(1978)
wing disc ML-DmD16-c3
(1729)
wing disc ML-DmD21
(3310)
wing disc ML-DmD32
(1455)
haltere disc ML-DmD17-c3
(1183)
eye-antennal disc ML-DmD11
(3003)
antennal disc ML-DmD20-c5
(2075)
mixed discs ML-DmD4-c1
(2271)
CNS ML-DmBG1-c1
(2133)
CNS ML-DmBG2-c2
(1335)
tumorous blood cells mbn2
(967)
ovary fGS/OSS
(1111)
ovary OSC
(944)
ovary OSS
(424)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
(1803)
Schneider line 2 Sg4
(1450)
embryonic 1182-4H
(2037)
embryonic GM2
(1301)
embryonic Kc167
(1169)
embryonic S1
(946)
embryonic S3
(1228)
leg disc CME L1
(2254)
wing disc CME-W2
(1510)
wing disc ML-DmD8
(2109)
wing disc ML-DmD9
(1978)
wing disc ML-DmD16-c3
(1729)
wing disc ML-DmD21
(3310)
wing disc ML-DmD32
(1455)
haltere disc ML-DmD17-c3
(1183)
eye-antennal disc ML-DmD11
(3003)
antennal disc ML-DmD20-c5
(2075)
mixed discs ML-DmD4-c1
(2271)
CNS ML-DmBG1-c1
(2133)
CNS ML-DmBG2-c2
(1335)
tumorous blood cells mbn2
(967)
ovary fGS/OSS
(1111)
ovary OSC
(944)
ovary OSS
(424)
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
1803
Schneider line 2 Sg4
1450
embryonic 1182-4H
2037
embryonic GM2
1301
embryonic Kc167
1169
embryonic S1
946
embryonic S3
1228
leg disc CME L1
2254
wing disc CME-W2
1510
wing disc ML-DmD8
2109
wing disc ML-DmD9
1978
wing disc ML-DmD16-c3
1729
wing disc ML-DmD21
3310
wing disc ML-DmD32
1455
haltere disc ML-DmD17-c3
1183
eye-antennal disc ML-DmD11
3003
antennal disc ML-DmD20-c5
2075
mixed discs ML-DmD4-c1
2271
CNS ML-DmBG1-c1
2133
CNS ML-DmBG2-c2
1335
tumorous blood cells mbn2
967
ovary fGS/OSS
1111
ovary OSC
944
ovary OSS
424
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
1803
Schneider line 2 Sg4
1450
embryonic 1182-4H
2037
embryonic GM2
1301
embryonic Kc167
1169
embryonic S1
946
embryonic S3
1228
leg disc CME L1
2254
wing disc CME-W2
1510
wing disc ML-DmD8
2109
wing disc ML-DmD9
1978
wing disc ML-DmD16-c3
1729
wing disc ML-DmD21
3310
wing disc ML-DmD32
1455
haltere disc ML-DmD17-c3
1183
eye-antennal disc ML-DmD11
3003
antennal disc ML-DmD20-c5
2075
mixed discs ML-DmD4-c1
2271
CNS ML-DmBG1-c1
2133
CNS ML-DmBG2-c2
1335
tumorous blood cells mbn2
967
ovary fGS/OSS
1111
ovary OSC
944
ovary OSS
424
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(1803)
Schneider line 2 Sg4
(1450)
embryonic 1182-4H
(2037)
embryonic GM2
(1301)
embryonic Kc167
(1169)
embryonic S1
(946)
embryonic S3
(1228)
leg disc CME L1
(2254)
wing disc CME-W2
(1510)
wing disc ML-DmD8
(2109)
wing disc ML-DmD9
(1978)
wing disc ML-DmD16-c3
(1729)
wing disc ML-DmD21
(3310)
wing disc ML-DmD32
(1455)
haltere disc ML-DmD17-c3
(1183)
eye-antennal disc ML-DmD11
(3003)
antennal disc ML-DmD20-c5
(2075)
mixed discs ML-DmD4-c1
(2271)
CNS ML-DmBG1-c1
(2133)
CNS ML-DmBG2-c2
(1335)
tumorous blood cells mbn2
(967)
ovary fGS/OSS
(1111)
ovary OSC
(944)
ovary OSS
(424)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
(1803)
Schneider line 2 Sg4
(1450)
embryonic 1182-4H
(2037)
embryonic GM2
(1301)
embryonic Kc167
(1169)
embryonic S1
(946)
embryonic S3
(1228)
leg disc CME L1
(2254)
wing disc CME-W2
(1510)
wing disc ML-DmD8
(2109)
wing disc ML-DmD9
(1978)
wing disc ML-DmD16-c3
(1729)
wing disc ML-DmD21
(3310)
wing disc ML-DmD32
(1455)
haltere disc ML-DmD17-c3
(1183)
eye-antennal disc ML-DmD11
(3003)
antennal disc ML-DmD20-c5
(2075)
mixed discs ML-DmD4-c1
(2271)
CNS ML-DmBG1-c1
(2133)
CNS ML-DmBG2-c2
(1335)
tumorous blood cells mbn2
(967)
ovary fGS/OSS
(1111)
ovary OSC
(944)
ovary OSS
(424)
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
1803
Schneider line 2 Sg4
1450
embryonic 1182-4H
2037
embryonic GM2
1301
embryonic Kc167
1169
embryonic S1
946
embryonic S3
1228
leg disc CME L1
2254
wing disc CME-W2
1510
wing disc ML-DmD8
2109
wing disc ML-DmD9
1978
wing disc ML-DmD16-c3
1729
wing disc ML-DmD21
3310
wing disc ML-DmD32
1455
haltere disc ML-DmD17-c3
1183
eye-antennal disc ML-DmD11
3003
antennal disc ML-DmD20-c5
2075
mixed discs ML-DmD4-c1
2271
CNS ML-DmBG1-c1
2133
CNS ML-DmBG2-c2
1335
tumorous blood cells mbn2
967
ovary fGS/OSS
1111
ovary OSC
944
ovary OSS
424
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
856
cold shock, 4-day adult
627
heat shock, 4-day adult
1416
Cadmium 50 mM 6 hrs, larvae L3
1305
Cadmium 50 mM 12 hrs, larvae L3
1483
Cadmium 50 mM 48 hrs, 4-day adult
1128
Cadmium 100 mM 48 hrs, 4-day adult
1040
Copper 0.5 mM 12 hrs, larvae L3
1066
Copper 15 mM 48 hrs, 4-day adult
555
Zinc 5 mM 12 hrs, larvae L3
879
Zinc 4.5 mM 48 hrs, 4-day adult
582
Ethanol 2.5% 3 hrs, larvae L3
1578
Ethanol 5% 3 hrs, larvae L3
1395
Ethanol 10% 3 hrs, larvae L3
1484
Caffeine 1.5 mg/ml 4 hrs, larvae L3
1436
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
1183
Caffeine 25 mg/ml 48 hrs, 4-day adult
524
Paraquat 5 mM 48 hrs, 4-day adult
1240
Paraquat 10 mM 48 hrs, 4-day adult
1520
Rotenone 2 μg 12 hrs, larvae L3
1357
Rotenone 8 μg 12 hrs, larvae L3
1758
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
(856)
cold shock, 4-day adult
(627)
heat shock, 4-day adult
(1416)
Cadmium 50 mM 6 hrs, larvae L3
(1305)
Cadmium 50 mM 12 hrs, larvae L3
(1483)
Cadmium 50 mM 48 hrs, 4-day adult
(1128)
Cadmium 100 mM 48 hrs, 4-day adult
(1040)
Copper 0.5 mM 12 hrs, larvae L3
(1066)
Copper 15 mM 48 hrs, 4-day adult
(555)
Zinc 5 mM 12 hrs, larvae L3
(879)
Zinc 4.5 mM 48 hrs, 4-day adult
(582)
Ethanol 2.5% 3 hrs, larvae L3
(1578)
Ethanol 5% 3 hrs, larvae L3
(1395)
Ethanol 10% 3 hrs, larvae L3
(1484)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(1436)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(1183)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(524)
Paraquat 5 mM 48 hrs, 4-day adult
(1240)
Paraquat 10 mM 48 hrs, 4-day adult
(1520)
Rotenone 2 μg 12 hrs, larvae L3
(1357)
Rotenone 8 μg 12 hrs, larvae L3
(1758)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
(856)
cold shock, 4-day adult
(627)
heat shock, 4-day adult
(1416)
Cadmium 50 mM 6 hrs, larvae L3
(1305)
Cadmium 50 mM 12 hrs, larvae L3
(1483)
Cadmium 50 mM 48 hrs, 4-day adult
(1128)
Cadmium 100 mM 48 hrs, 4-day adult
(1040)
Copper 0.5 mM 12 hrs, larvae L3
(1066)
Copper 15 mM 48 hrs, 4-day adult
(555)
Zinc 5 mM 12 hrs, larvae L3
(879)
Zinc 4.5 mM 48 hrs, 4-day adult
(582)
Ethanol 2.5% 3 hrs, larvae L3
(1578)
Ethanol 5% 3 hrs, larvae L3
(1395)
Ethanol 10% 3 hrs, larvae L3
(1484)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(1436)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(1183)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(524)
Paraquat 5 mM 48 hrs, 4-day adult
(1240)
Paraquat 10 mM 48 hrs, 4-day adult
(1520)
Rotenone 2 μg 12 hrs, larvae L3
(1357)
Rotenone 8 μg 12 hrs, larvae L3
(1758)
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
856
cold shock, 4-day adult
627
heat shock, 4-day adult
1416
Cadmium 50 mM 6 hrs, larvae L3
1305
Cadmium 50 mM 12 hrs, larvae L3
1483
Cadmium 50 mM 48 hrs, 4-day adult
1128
Cadmium 100 mM 48 hrs, 4-day adult
1040
Copper 0.5 mM 12 hrs, larvae L3
1066
Copper 15 mM 48 hrs, 4-day adult
555
Zinc 5 mM 12 hrs, larvae L3
879
Zinc 4.5 mM 48 hrs, 4-day adult
582
Ethanol 2.5% 3 hrs, larvae L3
1578
Ethanol 5% 3 hrs, larvae L3
1395
Ethanol 10% 3 hrs, larvae L3
1484
Caffeine 1.5 mg/ml 4 hrs, larvae L3
1436
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
1183
Caffeine 25 mg/ml 48 hrs, 4-day adult
524
Paraquat 5 mM 48 hrs, 4-day adult
1240
Paraquat 10 mM 48 hrs, 4-day adult
1520
Rotenone 2 μg 12 hrs, larvae L3
1357
Rotenone 8 μg 12 hrs, larvae L3
1758
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
856
cold shock, 4-day adult
627
heat shock, 4-day adult
1416
Cadmium 50 mM 6 hrs, larvae L3
1305
Cadmium 50 mM 12 hrs, larvae L3
1483
Cadmium 50 mM 48 hrs, 4-day adult
1128
Cadmium 100 mM 48 hrs, 4-day adult
1040
Copper 0.5 mM 12 hrs, larvae L3
1066
Copper 15 mM 48 hrs, 4-day adult
555
Zinc 5 mM 12 hrs, larvae L3
879
Zinc 4.5 mM 48 hrs, 4-day adult
582
Ethanol 2.5% 3 hrs, larvae L3
1578
Ethanol 5% 3 hrs, larvae L3
1395
Ethanol 10% 3 hrs, larvae L3
1484
Caffeine 1.5 mg/ml 4 hrs, larvae L3
1436
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
1183
Caffeine 25 mg/ml 48 hrs, 4-day adult
524
Paraquat 5 mM 48 hrs, 4-day adult
1240
Paraquat 10 mM 48 hrs, 4-day adult
1520
Rotenone 2 μg 12 hrs, larvae L3
1357
Rotenone 8 μg 12 hrs, larvae L3
1758
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
(856)
cold shock, 4-day adult
(627)
heat shock, 4-day adult
(1416)
Cadmium 50 mM 6 hrs, larvae L3
(1305)
Cadmium 50 mM 12 hrs, larvae L3
(1483)
Cadmium 50 mM 48 hrs, 4-day adult
(1128)
Cadmium 100 mM 48 hrs, 4-day adult
(1040)
Copper 0.5 mM 12 hrs, larvae L3
(1066)
Copper 15 mM 48 hrs, 4-day adult
(555)
Zinc 5 mM 12 hrs, larvae L3
(879)
Zinc 4.5 mM 48 hrs, 4-day adult
(582)
Ethanol 2.5% 3 hrs, larvae L3
(1578)
Ethanol 5% 3 hrs, larvae L3
(1395)
Ethanol 10% 3 hrs, larvae L3
(1484)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(1436)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(1183)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(524)
Paraquat 5 mM 48 hrs, 4-day adult
(1240)
Paraquat 10 mM 48 hrs, 4-day adult
(1520)
Rotenone 2 μg 12 hrs, larvae L3
(1357)
Rotenone 8 μg 12 hrs, larvae L3
(1758)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
(856)
cold shock, 4-day adult
(627)
heat shock, 4-day adult
(1416)
Cadmium 50 mM 6 hrs, larvae L3
(1305)
Cadmium 50 mM 12 hrs, larvae L3
(1483)
Cadmium 50 mM 48 hrs, 4-day adult
(1128)
Cadmium 100 mM 48 hrs, 4-day adult
(1040)
Copper 0.5 mM 12 hrs, larvae L3
(1066)
Copper 15 mM 48 hrs, 4-day adult
(555)
Zinc 5 mM 12 hrs, larvae L3
(879)
Zinc 4.5 mM 48 hrs, 4-day adult
(582)
Ethanol 2.5% 3 hrs, larvae L3
(1578)
Ethanol 5% 3 hrs, larvae L3
(1395)
Ethanol 10% 3 hrs, larvae L3
(1484)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(1436)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(1183)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(524)
Paraquat 5 mM 48 hrs, 4-day adult
(1240)
Paraquat 10 mM 48 hrs, 4-day adult
(1520)
Rotenone 2 μg 12 hrs, larvae L3
(1357)
Rotenone 8 μg 12 hrs, larvae L3
(1758)
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
856
cold shock, 4-day adult
627
heat shock, 4-day adult
1416
Cadmium 50 mM 6 hrs, larvae L3
1305
Cadmium 50 mM 12 hrs, larvae L3
1483
Cadmium 50 mM 48 hrs, 4-day adult
1128
Cadmium 100 mM 48 hrs, 4-day adult
1040
Copper 0.5 mM 12 hrs, larvae L3
1066
Copper 15 mM 48 hrs, 4-day adult
555
Zinc 5 mM 12 hrs, larvae L3
879
Zinc 4.5 mM 48 hrs, 4-day adult
582
Ethanol 2.5% 3 hrs, larvae L3
1578
Ethanol 5% 3 hrs, larvae L3
1395
Ethanol 10% 3 hrs, larvae L3
1484
Caffeine 1.5 mg/ml 4 hrs, larvae L3
1436
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
1183
Caffeine 25 mg/ml 48 hrs, 4-day adult
524
Paraquat 5 mM 48 hrs, 4-day adult
1240
Paraquat 10 mM 48 hrs, 4-day adult
1520
Rotenone 2 μg 12 hrs, larvae L3
1357
Rotenone 8 μg 12 hrs, larvae L3
1758
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 11 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 5 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Disrupted in Not duplicated in Not disrupted in Transgenic Constructs & Insertions
Transgenic Constructs Insertions insertion of mobile activating element
insertion of enhancer trap
Gene Ontology: Function, Process
& Cellular Component ( 6 unique terms ) Terms Based on
Experimental Evidence ( 4 terms ) Molecular Function inferred from direct assay
Biological Process inferred from mutant phenotype
inferred from mutant phenotype
Cellular Component inferred from direct assay
Terms Based on Predictions or
Assertions ( 4 terms ) Molecular Function inferred from sequence or structural similarity with
mouse Rpl19 non-traceable author statement
Biological Process inferred from sequence or structural similarity with
mouse Rpl19 Cellular Component inferred from sequence or structural similarity with
mouse Rpl19 non-traceable author statement
Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (45)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG6BVSF6 )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG637RQ6 )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG6FTTX3 )
Apis mellifera
Western honey bee
Amel\Ame.1133
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG013973
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH11819
Atta cephalotes
Leafcutter ant
Acep\ACEP27391
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO14070
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL19547
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL23800
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL20266
Linepithema humile
Argentine ant
Lhum\LH13145
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB23394
Solenopsis invicta
Red fire ant
Sinv\SINV21141
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG61JWVN )
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa
(EOG61CKRJ )
Caenorhabditis elegans
Nematode
Strongylocentrotus purpuratus
Purple sea urchin
Xenopus tropicalis
Western clawed frog
Gallus gallus
Domestic chicken
Rattus norvegicus
Norway rat
Rattus norvegicus
Norway rat
Rattus norvegicus
Norway rat
Rattus norvegicus
Norway rat
Rattus norvegicus
Norway rat
Human Orthologs (1)AAA Orthologs (10)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 3 )Bloomington Kyoto VDRC Genomic Clones ( 1 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 657 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for identity of: RpL19 CG2746
Source for database merge of Additional comments Other Comments RNAi screen using dsRNA made from templates generated with primers directed against this gene results in aberrantly short spindles when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without
Cdc27 dsRNA.
Molecularly-defined mutations in
RpL19 result in Minute phenotypes.
A deletion that removes
RpL19 and
RpL41 (a non-Minute gene) but no other cytoplasmic ribosomal protein-encoding genes shows Minute phenotypes.
RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
A screen that identified Dominant enhancers of the wing phenotype associated with
Dl9P and
DlFE32 identified
RpL19 .
Mutant alleles have the developmental delay and bristle phenotype that makes them useful as markers in clonal analysis.
One of a class of genes (see MIN record) that when present in one, rather than two, copies, produce a characteristic phenotype consisting of short slender bristles and delayed development.
External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 19 )Reported As Symbol Synonym RpL19
(
Goshima et al., 2007 ,
Tu and Johnston, 2008 ,
Demakov et al., 2004 ,
Hall et al., 2004 ,
Marygold et al., 2007 ,
Rhiner et al., 2010 ,
Mourikis et al., 2010 ,
Cook et al., 2012 ,
Killip and Grewal, 2012 )
Name Synonym Secondary FlyBase
IDs FBgn0010030 FBgn0022215 FBgn0025292 References ( 61 )Generate a list of List References by type
Recent research papers ( 6 )
Cook et al., 2012, Genome Biol. 13(3): R21The generation of chromosomal deletions to provide extensive coverage and subdivision of the Drosophila melanogaster genome. [FBrf0219066] Gaertner et al., 2012, Cell Rep. 2(6): 1670--1683Poised RNA Polymerase II Changes over Developmental Time and Prepares Genes for Future Expression. [FBrf0220312] Killip and Grewal, 2012, Dev. Biol. 371(2): 191--202DREF is required for cell and organismal growth in Drosophila and functions downstream of the nutrition/TOR pathway. [FBrf0219592] Booker et al., 2011, BMC Genomics 12: 50False negative rates in Drosophila cell-based RNAi screens: a case study. [FBrf0212969] Vatolina et al., 2011, Genetika, Moscow 47(5): 597--609[Identification and molecular genetic characterization of the polytene chromosome interbands in Drosophila melanogaster]. [FBrf0214456] Vatolina et al., 2011, Russ. J. Genet. 47(5): 521--532Identification and molecular genetic characterization of the polytene chromosome interbands in Drosophila melanogaster. [FBrf0216692]