rp49, M(3)99D, RP-49, L32, rp49/RpL32
Please see the JBrowse view of Dmel\RpL32 for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.47
Gene model reviewed during 6.61
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\RpL32 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\RpL32 in JBrowse3-100
3-97.4
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Haploinsufficient locus.
RNAi screen using dsRNA made from templates generated with primers directed against this gene results in aberrantly short, monopolar spindles when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA.
Minute gene.
RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
In a sample of 79 genes with multiple introns, 33 showed significant heterogeneity in G+C content among introns of the same gene and significant positive correspondence between the intron and the third codon position G+C content within genes. These results are consistent with selection adding against preferred codons at the start of genes.
Ecol\lacZDpt.PR adults are pricked with a sterile needle dipped in culture pellets of various living microorganisms (distinct bacterial strains, fungal spores or hyphae). Pricking results in a low but clearly detectable expression of all antimicrobial genes and these genes are induced above the background level by specific classes of microorganism.
Chromosome homologies of Muller's element D (J chromosome in the Paleartic species and XR chromosome arm in Nearctic species) and of element E (O chromosome in the Paleartic species and 2 chromosome in Nearctic species) have been confirmed by single copy probes in the species of the obscura group and in D.melanogaster.
Expression of transcript changes with adult age.
The molecular organization of the 'rp49-Sry-jan' gene cluster, including gene order, direction of transcription and partial overlap of the janA and janB genes is strictly conserved between D.melanogaster and D.pseudoobscura.pseudoobscura.
Ecdysteroid-regulated gene.
One of a class of genes that when present in one, rather than two, copies, produce a characteristic phenotype consisting of short slender bristles and delayed development.
An antisense RpL32 gene driven by a strong and inducible promoter was integrated into the Drosophila germline. Induction of the gene caused a weak Minute phenotype and the transient arrest of oogenesis.
Identification: Identified by the phenotype of heterozygotes for a synthetic deficiency.
Strong Minute; small bristles, slightly abnormal wings; eclosion delayed two to three days.
RNA blot analysis demonstrates that coordination between r-protein and rRNA synthesis is achieved by regulating translation of r-protein mRNAs in early embryos and by decreasing their abundance in adult tissues.
RpL32/+ females produce smaller than normal eggs; 10-15% of embryos fail to hatch often displaying fusion and partial deletion of segments posterior to A3.
Source for merge of: RpL32 BcDNA:RH03940
Source for merge of RpL32 BcDNA:RH03940 was a shared cDNA ( date:030728 ).
