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General Information
Symbol
Dmel\mal
Species
D. melanogaster
Name
maroon-like
Annotation Symbol
CG1692
Feature Type
FlyBase ID
FBgn0002641
Gene Model Status
Stock Availability
Enzyme Name (EC)
Molybdenum cofactor sulfurtransferase (2.8.1.9)
Gene Snapshot
Also Known As

ma-l, bz, bronzy

Key Links
Genomic Location
Cytogenetic map
Sequence location
X:20,429,675..20,433,210 [+]
Recombination map

1-64

RefSeq locus
NC_004354 REGION:20429675..20433210
Sequence
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (7 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
inferred from mutant phenotype
(assigned by UniProt )
inferred from mutant phenotype
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
inferred from sequence or structural similarity with UniProtKB:Q96EN8
(assigned by UniProt )
inferred from biological aspect of ancestor with PANTHER:PTN000716378
(assigned by GO_Central )
inferred from electronic annotation with InterPro:IPR005302
(assigned by InterPro )
inferred from electronic annotation with InterPro:IPR005302
(assigned by InterPro )
Biological Process (4 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
inferred from mutant phenotype
(assigned by UniProt )
inferred from mutant phenotype
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
inferred from electronic annotation with InterPro:IPR028886
(assigned by InterPro )
inferred from biological aspect of ancestor with PANTHER:PTN000716378
(assigned by GO_Central )
inferred from sequence or structural similarity with UniProtKB:Q96EN8
(assigned by UniProt )
Cellular Component (0 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Gene Group (FlyBase)
Protein Family (UniProt)
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily. (Q9VRA2)
Catalytic Activity (EC)
Experimental Evidence
Molybdenum cofactor + L-cysteine + reduced acceptor + 2 H(+) = thio- molybdenum cofactor + L-alanine + H(2)O + oxidized acceptor (2.8.1.9)
Predictions / Assertions
Molybdenum cofactor + L-cysteine + reduced acceptor + 2 H(+) = thio- molybdenum cofactor + L-alanine + H(2)O + oxidized acceptor (2.8.1.9)
Summaries
Gene Group (FlyBase)
SULFURTRANSFERASES -
Sulfurtransferases catalyze the transfer of sulfur-containing groups.
Protein Function (UniProtKB)
Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
(UniProt, Q9VRA2)
Phenotypic Description (Red Book; Lindsley and Zimm 1992)
mal: maroonlike
Brownish eye color resulting from reduction in the red (drosopterin) pigments. Larval Malpighian tubes short, bloated, irregularly formed, and contain yellow to orange pteridine globules (Schwinck, 1960, DIS 34: 105). mal is nonautonomous for eye color in mosaics with wild-type tissue (Glassman, 1957, DIS 31: 121-22) and in transplants of mal eyes into wild-type hosts (Ursprung, 1961, Z. Vererbungsl. 93: 119-25). Activities of three molybdo-enzymes reduced or absent: aldehyde oxidase = AO (Courtright, 1967, Genetics 57: 25-39), pyridoxal oxidase = PO (Forrest, Hanley, and Lagowski, 1961, Genetics 46: 1455-63), and xanthine dehydrogenase = XDH (Forrest, Glassman, and Mitchell, 1956, Science 124: 725-26; Glassman and Mitchell, 1959, Genetics 44: 153-62). Measurements of cross reacting material (e.g., Browder, Wilkes, and Tucker, 1982, Biochem. Genet. 20: 111-24, 125-32) show 75% and 50% normal levels of AO CRM in larval hemolymph and adult extracts respectively and 105% normal level of XDH CRM (see also Warner, Watts, and Finnerty, 1980, Mol. Gen. Genet. 180: 449-53). Activity of a fourth molybdo-enzyme, sulfite oxidase, is unaffected by mal (Bogart and Bernini, 1981, Biochem. Genet. 19: 929-46). Furthermore, unlike mutants in genes thought to be involved with the function of molybdenum cofactor, e.g. cin and lxd, the effects of mal not alleviated by administration of molybdenum; XDH cross reacting material (CRM) isolated from mal flies contains molybdenum (Andres, 1976, Eur. J. Biochem. 62: 591); mal flies contain high levels of molybdenum cofactor by Neurospora nitrate reductase activation assay (Warner and Finnerty, 1981, Mol. Gen. Genet, 184: 72-96). Accumulation of enzyme substrates (Forrest, Glassman, and Mitchell, 1956; Glassman and Mitchell, 1959; Glassman and McLean, 1962, Proc. Nat. Acad. Sci. USA 48: 1712-18) may account for the reported increase in uricase activity (Friedman, 1970, Genetics 68: s22). The absence of XDH activity renders mal flies sensitive to exogenously supplied purine (Glassman, 1965, Fed. Proc. 24: 1243), which has been used in selective schemes (Finnerty et al., 1970); the cell autonomy of mal with respect to AO activity provides the basis of a staining procedure for differentiating mal from mal+ tissue in mosaics (Janning, 1972, Naturwissenschaften 59: 516-17). mal offspring of mal+ mothers appear normal in both eye color and Malpighian-tube morphology (Glassman and Mitchell, 1959; Schwinck, 1960); mal+ activity observed in germ line as AO activity (Marsh and Wieschaus, 1977, Dev. Biol. 60: 396-403) and maternally inherited XDH activity in mal offspring detectable until second day of pupal stage (Browder and Williamson, 1976, Dev. Biol. 53: 241-49). Maternal effect suppressed if offspring are also homozygous for lxd (Courtright, 1975, Mol. Gen. Genet. 142: 231-38). Interallelic complementation in females of constitution mal1/malF1; eye color and Malpighian-tube morphology appear normal, but XDH activity about 10% normal (Glassman and Mitchell, 1959; Schwinck, 1960); complementation not seen in flies raised at 29 and reduced in flies that are also homozygous for lxd (Courtright, 1975, Mol. Gen. Genet. 142: 231-38); physical properties of XDH and AO altered in different heteroallelic combinations (Finnerty, McCarron, and Johnson, 1979, Mol. Gen. Genet. 172: 37-43; Finnerty and Johnson, 1979, Genetics 91: 696-722). mal1, malF1, and malF3 complement for eye color in all pairwise combinations; however, malF1 malF3/mal1 is mutant. mal and ry extracts complement to produce XDH activity (Glassman, 1962, Proc. Nat. Acad. Sci. USA 48: 1491-97); they do not complement intercellularly in vivo, however, since reciprocal eye-disk or Malpighian-tube transplants reported to behave autonomously with respect to drosopterin formation (Schwinck, 1960; 1963, DIS 38: 87).
Gene Model and Products
Number of Transcripts
2
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\mal for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.50

Gene model reviewed during 5.55

Sequence Ontology: Class of Gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
FBtr0077306
2749
781
FBtr0344987
3209
781
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
FBpp0076998
88.1
781
6.56
FBpp0311241
88.1
781
6.56
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

781 aa isoforms: mal-PA, mal-PB
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mal using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
organism

Comment: maternally deposited

Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\mal in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 38 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of mal
Transgenic constructs containing regulatory region of mal
Deletions and Duplications ( 125 )
Disrupted in
Not disrupted in
Phenotypes
Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (3)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
15 of 15
Yes
Yes
1 of 15
No
No
1 of 15
No
No
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (2)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
15 of 15
Yes
Yes
1 of 15
No
No
Rattus norvegicus (Norway rat) (4)
11 of 13
Yes
Yes
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
Xenopus tropicalis (Western clawed frog) (4)
2 of 12
Yes
Yes
2 of 12
Yes
Yes
1 of 12
No
No
1 of 12
No
No
Danio rerio (Zebrafish) (2)
9 of 15
Yes
Yes
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (4)
15 of 15
Yes
Yes
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
Arabidopsis thaliana (thale-cress) (6)
9 of 9
Yes
Yes
2 of 9
No
Yes
2 of 9
No
Yes
1 of 9
No
Yes
1 of 9
No
Yes
1 of 9
No
Yes
Saccharomyces cerevisiae (Brewer's yeast) (1)
1 of 15
Yes
Yes
Schizosaccharomyces pombe (Fission yeast) (0)
No records found.
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091902QU )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila simulans
Drosophila sechellia
Drosophila erecta
Drosophila yakuba
Drosophila ananassae
Drosophila pseudoobscura pseudoobscura
Drosophila persimilis
Drosophila willistoni
Drosophila virilis
Drosophila mojavensis
Drosophila grimshawi
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091501IE )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Lucilia cuprina
Australian sheep blowfly
Mayetiola destructor
Hessian fly
Aedes aegypti
Yellow fever mosquito
Aedes aegypti
Yellow fever mosquito
Aedes aegypti
Yellow fever mosquito
Anopheles darlingi
American malaria mosquito
Anopheles gambiae
Malaria mosquito
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W02LQ )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Danaus plexippus
Monarch butterfly
Heliconius melpomene
Postman butterfly
Apis florea
Little honeybee
Apis mellifera
Western honey bee
Bombus impatiens
Common eastern bumble bee
Bombus terrestris
Buff-tailed bumblebee
Linepithema humile
Argentine ant
Megachile rotundata
Alfalfa leafcutting bee
Nasonia vitripennis
Parasitic wasp
Dendroctonus ponderosae
Mountain pine beetle
Tribolium castaneum
Red flour beetle
Pediculus humanus
Human body louse
Rhodnius prolixus
Kissing bug
Cimex lectularius
Bed bug
Acyrthosiphon pisum
Pea aphid
Zootermopsis nevadensis
Nevada dampwood termite
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X02J2 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Strigamia maritima
European centipede
Daphnia pulex
Water flea
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G03KL )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Ciona intestinalis
Vase tunicate
Gallus gallus
Domestic chicken
Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (1)
3 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 1 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    esyN Network Diagram
    Interactions Browser
    Summary of Genetic Interactions
    esyN Network Diagram
    esyN Network Key:
    Suppression
    Enhancement

    Please look at the allele data for full details of the genetic interactions
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    External Data
    Linkouts
    DroID - A comprehensive database of gene and protein interactions.
    Pathways
    Signaling Pathways (FlyBase)
    Metabolic Pathways
    External Data
    Linkouts
    KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
    Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
    Genomic Location and Detailed Mapping Data
    Chromosome (arm)
    X
    Recombination map

    1-64

    Cytogenetic map
    Sequence location
    X:20,429,675..20,433,210 [+]
    FlyBase Computed Cytological Location
    Cytogenetic map
    Evidence for location
    19D1-19D1
    Limits computationally determined from genome sequence between P{EP}amnEP1639&P{EP}amnEP367 and P{EP}CG1702EP1525
    Experimentally Determined Cytological Location
    Cytogenetic map
    Notes
    References
    Experimentally Determined Recombination Data
    Location
    Left of (cM)
    Right of (cM)
    Notes
    Stocks and Reagents
    Stocks (39)
    Genomic Clones (12)
     

    Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

    cDNA Clones (27)
     

    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

    cDNA clones, fully sequenced
    BDGP DGC clones
    Other clones
    Drosophila Genomics Resource Center cDNA clones

    For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

    cDNA Clones, End Sequenced (ESTs)
    RNAi and Array Information
    Linkouts
    DRSC - Results frm RNAi screens
    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
    Antibody Information
    Laboratory Generated Antibodies
     
    Commercially Available Antibodies
     
    Other Information
    Relationship to Other Genes
    Source for database identify of

    Source for identity of: mal CG1692

    Source for database merge of
    Additional comments

    The alleles of mal have been mapped both by complementation for eye color and by recombination. Five complementation units have been defined (Chovnick, Finnerty, Schalet and Duck, 1969) and malC2 said to define a sixth (Bentley and Williamson, 1982). There is but a single lethal complementation group in heteroallelic combinations raised on purine-enriched medium. Recombinational mapping utilized purine sensitivity to select for mal+ recombinants (Finnerty, Duck and Chovnick, 1970). Maps co-linear.

    Other Comments

    Lesions in mal affect eye pigmentation to a small extent only.

    Mutations at mal are fully viable, have a maternal effect phenotype and exhibit a brownish eye colour. Larval Malpighian tubules can be short, bloated and irregularly formed.

    Aldehyde oxidase deficient mutants of mal have appreciable levels of aldehyde oxidase cross-reacting material in both larval haemolymph and adult extracts.

    Rocket immunoelectrophoresis was used to estimate xanthine dehydrogenase cross-reacting material (XDH-CRM). Results show high levels of XDH-CRM in mutant mal flies, this suggests that the primary effects of the mutant gene is on the function of XDH protein rather than its accumulation.

    Mutations of mal exhibit the same levels of sulfite oxidase activity as wild-type flies. Xanthine dehydrogenase and aldehyde oxidase cannot be detected, but there are wild-type levels of alcohol dehydrogenase.

    Brownish eye color resulting from reduction in the red (drosopterin) pigments. Larval Malpighian tubes short, bloated, irregularly formed and contain yellow to orange pteridine globules (Schwinck, 1960). mal is nonautonomous for eye color in mosaics with wild-type tissue (Glassman, 1957) and in transplants of mal eyes into wild-type hosts (Ursprung, 1961). Activities of three molybdo-enzymes reduced or absent: aldehyde oxidase = AO (Courtright, 1967), pyridoxal oxidase = PO (Forrest, Hanley and Lagowski, 1961) and xanthine dehydrogenase = XDH (Forrest, Glassman and Mitchell, 1956) (Glassman and Mitchell, 1959). Measurements of cross-reacting material (e.g., Browder, Wilkes and Tucker, 1982; Browder, Tucker and Wilkes, 1982) show 75% and 50% normal levels of AO CRM in larval hemolymph and adult extracts respectively and 105% normal level of XDH CRM (see also Warner, Watts and Finnerty, 1980). Activity of a fourth molybdo-enzyme, sulfite oxidase, is unaffected by mal (Bogart and Bernini, 1981). Furthermore, unlike mutants in genes thought to be involved with the function of molybdenum cofactor, e.g. cin and lxd, the effects of mal not alleviated by administration of molybdenum; XDH cross reacting material (CRM) isolated from mal flies contains molybdenum (Andres, 1976); mal flies contain high levels of molybdenum cofactor by Neurospora nitrate reductase activation assay (Warner and Finnerty, 1981). Accumulation of enzyme substrates (Forrest, Glassman and Mitchell, 1956; Glassman and Mitchell, 1959; Glassman and McLean, 1962) may account for the reported increase in uricase activity (Friedman, 1970). The absence of XDH activity renders mal flies sensitive to exogenously supplied purine (Glassman, 1965), which has been used in selective schemes (Finnerty, Duck and Chovnick, 1970); the cell autonomy of mal with respect to AO activity provides the basis of a staining procedure for differentiating mal from mal+ tissue in mosaics (Janning, 1972). mal offspring of mal+ mothers appear normal in both eye color and Malpighian-tube morphology (Glassman and Mitchell, 1959; Schwinck, 1960); mal+ activity observed in germ line as AO activity (Marsh and Wieschaus, 1977) and maternally inherited XDH activity in mal offspring detectable until second day of pupal stage (Browder and Williamson, 1976). Maternal effect suppressed if offspring are also homozygous for lxd (Courtright, 1975). Interallelic complementation in females of constitution mal1/malF1; eye color and Malpighian-tube morphology appear normal, but XDH activity about 10% normal (Glassman and Mitchell, 1959; Schwinck, 1960); complementation not seen in flies raised at 29oC and reduced in flies that are also homozygous for lxd (Courtright, 1975); physical properties of XDH and AO altered in different heteroallelic combinations (Finnerty, McCarron and Johnson, 1979; Finnerty and Johnson, 1979). mal1, malF1, and malF3 complement for eye color in all pairwise combinations; however, malF1 malF3/mal1 is mutant. mal and ry extracts complement to produce XDH activity (Glassman, 1962); they do not complement intercellularly in vivo, however, since reciprocal eye-disk or Malpighian-tube transplants reported to behave autonomously with respect to drosopterin formation (Schwinck, 1960; Schwinck, 1963).

    Origin and Etymology
    Discoverer
    Etymology
    Identification
    External Crossreferences and Linkouts ( 42 )
    Sequence Crossreferences
    NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
    GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
    GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
    RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
    UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
    UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
    Other crossreferences
    BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
    Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
    Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
    Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
    Flygut - An atlas of the Drosophila adult midgut
    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
    iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
    KEGG Genes - Molecular building blocks of life in the genomic space.
    modMine - A data warehouse for the modENCODE project
    Linkouts
    DPiM - Drosophila Protein interaction map
    DroID - A comprehensive database of gene and protein interactions.
    DRSC - Results frm RNAi screens
    FLIGHT - Cell culture data for RNAi and other high-throughput technologies
    FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
    FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
    FlyMine - An integrated database for Drosophila genomics
    KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
    Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
    Synonyms and Secondary IDs (10)
    Datasets (0)
    Study focus (0)
    Experimental Role
    Project
    Project Type
    Title
    References (121)