Gene model reviewed during 5.53
Gene model reviewed during 6.04
Multiphase exon postulated: this gene shares a region of coding sequence with an overlapping gene, but different reading frames are utilized in the overlapping coding region.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mei-218 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\mei-218 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Dicistronic annotation CG33067 split out into separate annotations for each open reading frame, CG33935 and CG8923, in release 4.2 of the genome annotation. CG33935 corresponds to mei-217 and CG8923 corresponds to mei-218.
Complete absence of the mei-218 gene product reduces, but does not eliminate, meiotic crossing over.
nod protein persists on the meiotic chromosomes until the completion of meiosis.
mei-218 mutants show a failure of metaphase arrest similar to that observed for the All-Compound genotype.