Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.45
Gene model reviewed during 5.56
None of the polypeptides share 100% sequence identity.
184 (aa); 20 (kD observed)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Mp20 using the Feature Mapper tool.
At embryonic stage 15, Mp20 transcript is expressed at a high level in ventral acute muscle 2 and A1-7 dorsal transverse muscle 1, at a median level in the segment border muscle, at low levels in dorsal acute muscle 1 and is not detectable in ventral transverse muscle 1.
Mp20 transcripts accumulate in primary myogenic tissue culture cells that have undergone differentiation into myotubes. Mp20 transcripts become detectable in 12-24 hr embryos, and are present at moderately high levels in larvae. Expression is lower in pupae, disappears in 1-3 day pupae, and reappears in 4-5 day pupae. The 1.0 and 0.9 kb tr! GAT21. Expression pattern ascribed to :
GBrowse - Visual display of RNA-Seq signalsView Dmel\Mp20 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
RNAi screen using dsRNA made from templates generated with primers directed against this gene causes a phenotype when assayed in S2R+ cells: cells become round and detached. Kc167 cells are unaffected.
In a sample of 79 genes with multiple introns, 33 showed significant heterogeneity in G+C content among introns of the same gene and significant positive correspondence between the intron and the third codon position G+C content within genes. These results are consistent with selection adding against preferred codons at the start of genes.
Mutation rate at microsatellite loci in 119 lines maintained for approximately 250 generations is estimated to be 6.3x10-6, at least one order of magnitude lower than the mutation rate in mammals.
Encodes a 20kD protein that is not detected in the asynchronous oscillatory flight muscles, but is found in most, if not all, other muscles (the synchronous muscles).