Mst26Ab, Acp26A, Acp26Aab, mst355b, mst 355b
Gene model reviewed during 5.51
0.5 (northern blot)
90 (aa); 11-14 (kD observed); 10 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Acp26Ab using the Feature Mapper tool.
In unmated adult males, Acp26Ab transcript levels remain constant for the first 14 days of adult life and were not tested beyond that.
Acp26Ab transcripts were assayed in hand-sorted staged pupae. They are first detected at pupal stage 13. They are present at adult levels by one day after eclosion and persist at these levels for at least 10 days. Determination of expression occurs during the third larval instar which correlates with the time of determination of the accessory glands.
Acp26Ab protein is not detectable in stage P13 pupae but is detectable in accessory glands dissected from adult males 3-4 hours after eclosion. Levels reach a plateau about 3-5 days after eclosion. Levels remain high in accessory gland secretions, even in 30 day old virgin males. Staining is present in both the main cells and the secondary cells of the accessory gland. In 5 day and older virgin males, protein is absent in the main cells but is present in the secondary cells where it is concentrated in large vesicles. Abundance of Acp2 Ab protein is stimulated by copulation. Acp26Ab protein is detected in the female genital tract 10 minutes after the start of copulation as well as in the hemolymph. It is no longer detected in the hemolymph by 2 hours after copulation and in the female genital tract by 2-3 hours after copulation. Protein was not detected in any other tissue examined.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Acp26Ab in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
If females remate frequently relative to the duration of sperm storage and rate of sperm use, sperm displacement may be an important component of male reproductive success. Significant association has been found between Acp26Ab mutant male sperm and the ability to resist displacement by subsequent sperm. There is no correlation between the ability to displace resident sperm and the ability to resist being displaced by subsequent sperm, this lack of correlation suggests that different mechanisms mediate that the two components of sperm displacement.
Sequence and restriction map polymorphism studied in 10 isogenic lines of D.melanogaster, and one line each of D.sechellia, D.mauritiana and D.simulans : pattern suggests selection in or near Acp26Aa-Acp26Ab region has played a part in the history of these genes.
Expressed in males, not females. Presence of tra2+ activity in XX flies during a part of the third larval instar is sufficient to repress expression of Acp26Ab and prevent accessory-gland formation and the production of Acp26Ab transcript.