Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.47
All cysteine residues are arranged in C-X-C groups. These are thought to be the metal-binding sites in other metallothioneins.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\MtnA using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\MtnA in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
In a sample of 79 genes with multiple introns, 33 showed significant heterogeneity in G+C content among introns of the same gene and significant positive correspondence between the intron and the third codon position G+C content within genes. These results are consistent with selection adding against preferred codons at the start of genes.
MtnA promoter expression induced by CuSO4 in recombinant baculovirus is inducible but 'leaky'.
Codes for metallothionein, a metal binding protein. Inducible by ingestion of Cu or Cd (but not Zn) ions. In larvae, it is expressed mainly in the midgut. No point mutations are available, but Dp(3;3)Mtn+H22 shows increased tolerance to Cd.