FB2020_06, released Dec 22, 2020

Gene: Dmel\mus301

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General Information
Symbol
Dmel\mus301
Species
D. melanogaster
Name
mutagen-sensitive 301
Annotation Symbol
CG7972
Feature Type
protein_coding_gene
FlyBase ID
FBgn0002899
Gene Model Status
Current
Stock Availability
13 publicly available
Gene Snapshot
mutagen-sensitive 301 (mus301) encodes a member of the Mus308 subfamily of ATP-dependent helicases. It is involved in the repair of double-strand DNA breaks during recombination and in somatic cells, and in chromosome segregation. It contributes to dorsal-ventral patterning during oogenesis and posterior oocyte positioning. [Date last reviewed: 2019-03-14]
Other Summaries
Also Known As

spn-C, spnC, spindle-C

Key Links
Genomic Location
Cytogenetic map
66B8-66B8
Sequence location
3L:8,137,808..8,142,014 [+]
Recombination map

3-22

RefSeq locus
NT_037436 REGION:8137808..8142014
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (13 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
enables ATP binding
inferred from electronic annotation with InterPro:IPR011545
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
enables nucleic acid binding
inferred from electronic annotation with InterPro:IPR011545
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
enables single-stranded 3'-5' DNA helicase activity
inferred from sequence or structural similarity with UniProtKB:Q8TDG4
(FlyBase Curators, 2008--)
Biological Process (9 terms)
Terms Based on Experimental Evidence (7 terms)
CV Term
Evidence
References
involved_in female meiosis chromosome segregation
inferred from mutant phenotype
(McCaffrey et al., 2006)
involved_in germarium-derived oocyte fate determination
inferred from mutant phenotype
(McCaffrey et al., 2006)
inferred from genetic interaction with FLYBASE:spn-A; FB:FBgn0003479
(Gonzalez-Reyes et al., 1997)
involved_in intracellular mRNA localization
inferred from mutant phenotype
(Gonzalez-Reyes et al., 1997)
involved_in oocyte karyosome formation
inferred from mutant phenotype
(McCaffrey et al., 2006, Gonzalez-Reyes et al., 1997)
involved_in oogenesis
inferred from genetic interaction with FLYBASE:fs(1)K10; FB:FBgn0000810
(Gonzalez-Reyes et al., 1997)
involved_in polarity specification of anterior/posterior axis
inferred from mutant phenotype
(Gonzalez-Reyes et al., 1997)
involved_in polarity specification of dorsal/ventral axis
inferred from mutant phenotype
(Gonzalez-Reyes et al., 1997)
Terms Based on Predictions or Assertions (4 terms)
CV Term
Evidence
References
involved_in intracellular mRNA localization
traceable author statement
(Cooperstock and Lipshitz, 1997)
involved_in oogenesis
traceable author statement
(van Eeden and St. Johnston, 1999)
involved_in regulation of translation
traceable author statement
(Cooperstock and Lipshitz, 1997)
involved_in rRNA processing
inferred from biological aspect of ancestor with PANTHER:PTN002776205
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
located_in nucleus
inferred from biological aspect of ancestor with PANTHER:PTN002776205
(assigned by GO_Central )
(Gaudet et al., 2011)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
OTHER DNA HELICASES -
The 'other DNA helicases' group comprises DNA helicases that do not fit into any of the other major DNA helicase groups.
Phenotypic Description (Red Book; Lindsley and Zimm 1992)
mus301 (J.B. Boyd)
Larval survival hypersensitive to exposure to X rays (Oliveri, Harris, and Boyd, 1990, Mutat. Res. 235: 25-31), methyl methanesulfonate, and nitrogen mustard. When fertile, homozygous females exhibit elevated frequencies of nondisjunction.
spn-C: spindle C
Maternal-effect lethal. Similar to spn-A.
Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\mus301 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.45

Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
mus301-RA
FBtr0076689
NM_139921
3364
1051
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
mus301-PA
FBpp0076412
117.3
1051
6.30
NP_648178
AAF50481
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mus301 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\mus301 in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 20 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of mus301
Transgenic constructs containing regulatory region of mus301
Deletions and Duplications ( 2 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
viable
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
Sterility
Allele
fertile
Other Phenotypes
Allele
chemical sensitive
chemical sensitive (with Df(3L)66C-G28)
chemical sensitive (with mus301094)
chemical sensitive (with mus301660)
chemical sensitive (with mus301D1)
chemical sensitive (with mus301D2)
chemical sensitive (with mus301D4)
chemical sensitive | recessive
decreased fecundity | female
radiation sensitive
short lived | heat sensitive, with Scer\GAL4tin.CΔ4
Phenotype manifest in
Allele
dorsal appendage
egg | dorsal
egg | maternal effect (with Df(3L)66C-G28)
egg | maternal effect (with mus301094)
egg | maternal effect (with mus301422)
egg | maternal effect (with mus301660)
egg | maternal effect (with mus301D1)
egg | maternal effect (with mus301D2)
egg | maternal effect (with mus301D4)
egg chamber
egg chorion | maternal effect (with mus301094)
egg chorion | maternal effect (with mus301D4)
germline cyst
karyosome
karyosome (with Df(3L)66C-G28)
karyosome (with mus301094)
karyosome (with mus301422)
karyosome (with mus301660)
karyosome (with mus301D1)
karyosome (with mus301D2)
karyosome (with mus301D4)
nurse cell
oocyte
oocyte (with Df(3L)66C-G28)
oocyte (with mus301D2)
oocyte (with mus301D4)
oocyte nucleus (with Df(3L)66C-G28)
oocyte nucleus (with mus301094)
oocyte nucleus (with mus301422)
oocyte nucleus (with mus301D1)
oocyte nucleus (with mus301D2)
oocyte nucleus (with mus301D4)
synaptonemal complex
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (6)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\HELQ
15 of 15
Yes
Yes
Hsap\POLQ
3 of 15
No
No
Hsap\DDX60
1 of 15
No
Yes
Hsap\DDX60L
1 of 15
No
Yes
Hsap\POLG
1 of 15
No
No
Hsap\POLN
1 of 15
No
No
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (5)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Helq
14 of 15
Yes
Yes
Mmus\Polq
3 of 15
No
No
Mmus\Ddx60
1 of 15
No
Yes
Mmus\Polg
1 of 15
No
No
Mmus\Poln
1 of 15
No
No
Rattus norvegicus (Norway rat) (4)
Rnor\Helq
13 of 13
Yes
Yes
Rnor\Polq
2 of 13
No
No
Rnor\Polg
1 of 13
No
No
Rnor\Poln
1 of 13
No
No
Xenopus tropicalis (Western clawed frog) (3)
Xtro\helq
9 of 12
Yes
Yes
Xtro\polq
2 of 12
No
No
Xtro\polg
1 of 12
No
No
Danio rerio (Zebrafish) (4)
Drer\helq
13 of 15
Yes
Yes
Drer\polq
3 of 15
No
No
Drer\polg
1 of 15
No
No
Drer\poln
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (3)
Cele\helq-1
14 of 15
Yes
Yes
Cele\polq-1
3 of 15
No
No
Cele\polg-1
1 of 15
No
No
Arabidopsis thaliana (thale-cress) (3)
Atha\AT4G32700
2 of 9
Yes
No
Atha\AT3G09720
1 of 9
No
No
Atha\EMB25
1 of 9
No
No
Saccharomyces cerevisiae (Brewer's yeast) (1)
Scer\MIP1
1 of 15
Yes
No
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\SPAC23A1.19c
1 of 12
Yes
Yes
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091901J9 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00003694
Drosophila simulans
Dsim\GD14056
Drosophila sechellia
Dsec\GM25023
Drosophila erecta
Dere\GG14474
Drosophila yakuba
Dyak\GE21661
Drosophila ananassae
Dana\GF23962
Drosophila pseudoobscura pseudoobscura
Dpse\GA20732
Drosophila persimilis
Dper\GL22611
Drosophila willistoni
Dwil\GK20010
Drosophila virilis
Dvir\GJ13152
Drosophila mojavensis
Dmoj\GI13326
Drosophila grimshawi
Dgri\GH16173
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915032P )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17015351
Glossina morsitans
Tsetse fly
Gmor\GMOY008033
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_05143
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_00624
Mayetiola destructor
Hessian fly
Mdes\Mdes005167
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL011649
Anopheles darlingi
American malaria mosquito
Adar\ADAC003918
Anopheles gambiae
Malaria mosquito
Agam\AGAP012297
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ020174
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ010550
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W03QE )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA013718
Danaus plexippus
Monarch butterfly
Dple\DPOGS204780-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL017693
Apis florea
Little honeybee
Aflo\2147684691
Apis mellifera
Western honey bee
Amel\GB48075
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP16750
Bombus terrestris
Buff-tailed bumblebee
Bter\15211881
Linepithema humile
Argentine ant
Lhum\LH13752
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:001dc7
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG014249
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_06823
Tribolium castaneum
Red flour beetle
Tcas\TC001346
Pediculus humanus
Human body louse
Phum\PHUM530580
Rhodnius prolixus
Kissing bug
Rpro\RPRC014077
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI004507
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_10984
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X03NG )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR004679
Ixodes scapularis
Black-legged tick
Isca\ISCW003708
Stegodyphus mimosarum
African social velvet spider
Smim\KFM57964.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur34g00860
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_320958
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G021D )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Hel308
Strongylocentrotus purpuratus
Purple sea urchin
Spur\SPU_017936gn
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000006332
Gallus gallus
Domestic chicken
Ggal\HELQ
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (37)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
PolQ
4 of 10
abs
1 of 10
bel
1 of 10
Brr2
1 of 10
CG5589
1 of 10
CG5800
1 of 10
CG6418
1 of 10
CG7483
1 of 10
CG7878
1 of 10
CG8611
1 of 10
CG9143
1 of 10
CG9253
1 of 10
CG9630
1 of 10
CG10077
1 of 10
CG10333
1 of 10
CG14443
1 of 10
CG32344
1 of 10
Dbp21E2
1 of 10
Dbp45A
1 of 10
Dbp73D
1 of 10
Dbp80
1 of 10
Ddx1
1 of 10
eIF4A
1 of 10
Gem3
1 of 10
Hel25E
1 of 10
Hlc
1 of 10
mahe
1 of 10
me31B
1 of 10
Mtr4
1 of 10
obe
1 of 10
pit
1 of 10
PolG1
1 of 10
Prp5
1 of 10
Rm62
1 of 10
Rs1
1 of 10
tst
1 of 10
vas
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    HELQ; helicase, POLQ like
    15 of 15
    606769
        POLQ; DNA polymerase theta
        3 of 15
        604419
            Functional Complementation Data
            Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
            Interactions
            Summary of Physical Interactions
            esyN Network Diagram
            Interactions Browser
            Summary of Genetic Interactions
            esyN Network Diagram
            esyN Network Key:
            Suppression
            Enhancement
            View in Interactions Browser
            Please look at the allele data for full details of the genetic interactions
            Starting gene(s)
            Interaction type
            Interacting gene(s)
            Reference
            mus301
            suppressible
            mei-41
            (Masrouha et al., 2003, Ghabrial and Schupbach, 1999)
            mus301
            suppressible
            mei-W68
            (Ghabrial and Schupbach, 1999)
            Starting gene(s)
            Interaction type
            Interacting gene(s)
            Reference
            External Data
            Linkouts
            BioGRID - A database of protein and genetic interactions.
            DroID - A comprehensive database of gene and protein interactions.
            InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
            MIST (genetic) - An integrated Molecular Interaction Database
            MIST (protein-protein) - An integrated Molecular Interaction Database
            Pathways
            Signaling Pathways (FlyBase)
            Metabolic Pathways
            External Data
            Linkouts
            Genomic Location and Detailed Mapping Data
            Chromosome (arm)
            3L
            Recombination map

            3-22

            Cytogenetic map
            66B8-66B8
            Sequence location
            3L:8,137,808..8,142,014 [+]
            FlyBase Computed Cytological Location
            Cytogenetic map
            Evidence for location
            66B8-66B8
            Limits computationally determined from genome sequence between P{PZ}l(3)0721708223&P{EP}Rac2EP3118 and P{lacW}Nmtj1C7
            Experimentally Determined Cytological Location
            Cytogenetic map
            Notes
            References
            Experimentally Determined Recombination Data
            Location

            3-22

            (FlyBase, 2016)

            3-19.0

            (Comeron et al., 2012)

            3-23

            (Gonzalez-Reyes et al., 1997)

            3-17

            (Tearle and Nusslein-Volhard, 1987)

            3-

            (Boyd et al., 1981)
            Left of (cM)
            (McCaffrey et al., 2006)
            Right of (cM)
            Notes
            Stocks and Reagents
            Stocks (13)
            Genomic Clones (17)
             

            Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

            cDNA Clones (10)
             

            Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

            cDNA clones, fully sequenced
            BDGP DGC clones
            Other clones
              Drosophila Genomics Resource Center cDNA clones

              For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

              cDNA Clones, End Sequenced (ESTs)
              BDGP DGC clones
              Other clones
              RNAi and Array Information
              Linkouts
              DRSC - Results frm RNAi screens
              GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
              Antibody Information
              Laboratory Generated Antibodies
               
              Commercially Available Antibodies
               
              Other Information
              Relationship to Other Genes
              Source for database identify of
              Source for database merge of

              Source for merge of: mus301 spn-C

              (Ghabrial and Schupbach, 1999)

              Source for merge of: mus301 CG7972

              (Laurencon et al., 2004)

              Source for merge of: mus301 anon-WO0118547.354

              (FlyBase, 1996-)
              Additional comments

              Source for merge of mus301 anon-WO0118547.354 was sequence comparison ( date:051113 ).

              (FlyBase, 1996-)
              Other Comments

              mus301 is involved in chromosome segregation in meiosis and in the repair of double-strand-DNA breaks in both meiotic and mitotic cells.

              (McCaffrey et al., 2006)

              Area matching Drosophila EST AI518328.

              (Davies, 2001.3.15)

              Analysis of mutants of the 5 spindle genes (spn-A, spn-B, mus301, spn-D and spn-E) reveals that the group of genes is required for each of the symmetry-breaking steps that generate polarity during axis formation. spn-E is required for the localisation of fs(1)K10, bcd and osk mRNAs, spn-A. spn-B, mus301 and spn-D play an indirect role in this process.

              (Gonzalez-Reyes et al., 1997)

              Analysis of egg chambers in mus301 mutants led to the conclusion that AP polarity within the oocyte is defined by the position of the oocyte in the egg chamber.

              (Gonzalez-Reyes and St. Johnston, 1994)

              Larval survival hypersensitive to exposure to X rays (Oliveri, Harris and Boyd, 1990), methyl methanesulfonate and nitrogen mustard. When fertile, homozygous females exhibit elevated frequencies of nondisjunction.

              Origin and Etymology
              Discoverer
              Etymology
              Identification
              External Crossreferences and Linkouts ( 32 )
              Sequence Crossreferences
              NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
              GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
              GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
              RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
              UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
              Other crossreferences
              Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
              Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
              Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
              Flygut - An atlas of the Drosophila adult midgut
              GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
              iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
              InterPro - A database of protein families, domains and functional sites
              KEGG Genes - Molecular building blocks of life in the genomic space.
              modMine - A data warehouse for the modENCODE project
              Linkouts
              BioGRID - A database of protein and genetic interactions.
              DroID - A comprehensive database of gene and protein interactions.
              DRSC - Results frm RNAi screens
              FLIGHT - Cell culture data for RNAi and other high-throughput technologies
              FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
              FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
              FlyMine - An integrated database for Drosophila genomics
              InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
              MIST (genetic) - An integrated Molecular Interaction Database
              MIST (protein-protein) - An integrated Molecular Interaction Database
              Synonyms and Secondary IDs (13)
              Datasets (0)
              Study focus (0)
              Experimental Role
              Project
              Project Type
              Title
              References (81)