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Gene Dmel\mus301

General Information
Symbol	Dmel\mus301	Species	D. melanogaster
Name	mutagen-sensitive 301	Annotation symbol	CG7972
Feature type	protein_coding_gene	FlyBase ID	FBgn0002899
Gene Model Status	Current	Stock availability	10 publicly available
Also Known As	spn-C, spnC
Genomic Location
Chromosome (arm)	3L	Recombination map	3-23
Cytogenetic map	66B8-66B8	Sequence location	3L:8,130,914..8,135,114 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene mutagen-sensitive 301 is referred to in FlyBase by the symbol Dmel\mus301 (CG7972, FBgn0002899). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: helicase activity. There is experimental evidence that it is involved in the biological process: female meiosis chromosome segregation; germarium-derived oocyte fate determination; polarity specification of dorsal/ventral axis; intracellular mRNA localization; oogenesis; polarity specification of anterior/posterior axis; karyosome formation. 21 alleles are reported. The phenotypes of these alleles are annotated with: germline cyst; oocyte; karyosome; egg chamber; oocyte nucleus; dorsal appendage; nurse cell; synaptonemal complex. It has one annotated transcript and one annotated polypeptide. Protein features are: DEAD-like helicase; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1638294_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of mus301. Gene sequence location is 3L:8130914..8135114.
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	mus301 (J.B. Boyd) Larval survival hypersensitive to exposure to X rays (Oliveri, Harris, and Boyd, 1990, Mutat. Res. 235: 25-31), methyl methanesulfonate, and nitrogen mustard. When fertile, homozygous females exhibit elevated frequencies of nondisjunction. spn-C: spindle C Maternal-effect lethal. Similar to spn-A.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features HFA10939 BKN20350
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 66B8-66B8   Limits computationally determined from genome sequence between P{PZ}l(3)0721708223&P{EP}Rac2EP3118 and P{lacW}Nmtj1C7
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location	3-23 (Gonzalez-Reyes et al., 1997, ) 3- (Boyd et al., 1981) 3-17 (Tearle and Nusslein-Volhard, 1987)
Left of (cM)	h P{lacW}l(3)S090314S090314 (McCaffrey et al., 2006)
Right of (cM)	ru
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\mus301 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) mus301-RA FBtr0076689  NM_139921   3358   1051
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein mus301-PA   FBpp0076412   117.3   1051   6.30     NP_648178   AAF50481
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Helicase, C-terminal (IPR001650) DNA/RNA helicase, DEAD/DEAH box type, N-terminal (IPR011545) DEAD-like helicase (IPR014001)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF50481   AI518328   AX094230   BI361900   BI365436   BT011090   CL528247   CZ467820   EC052635   EC052641   EC052642   EC054112   EC054820   EC056404
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VSE2
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0002899    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0002899 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0002899 expression level Developmental Stage   Expression Level embryo 00-02hr    1925 embryo 02-04hr    144 embryo 04-06hr    192 embryo 06-08hr    386 embryo 08-10hr    289 embryo 10-12hr    168 embryo 12-14hr    84 embryo 14-16hr    72 embryo 16-18hr    77 embryo 18-20hr    34 embryo 20-22hr    24 embryo 22-24hr    28 larva L1    95 larva L2    174 larva L3 12hr old    131 larva L3 puffstage 1-2    149 larva L3 puffstage 3-6    181 larva L3 puffstage 7-9    211 white prepupae new    198 white prepupae 12hr    269 white prepupae 24hr    203 pupae 2d postWPP    81 pupae 3d postWPP    50 pupae 4d postWPP    70 adult male 01day    77 adult male 05day    102 adult male 30day    105 adult female 01day    457 adult female 05day    1253 adult female 30day    1228 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1925) embryo 02-04hr  (144) embryo 04-06hr  (192) embryo 06-08hr  (386) embryo 08-10hr  (289) embryo 10-12hr  (168) embryo 12-14hr    84 embryo 14-16hr    72 embryo 16-18hr    77 embryo 18-20hr    34 embryo 20-22hr    24 embryo 22-24hr    28 larva L1    95 larva L2  (174) larva L3 12hr old  (131) larva L3 puffstage 1-2  (149) larva L3 puffstage 3-6  (181) larva L3 puffstage 7-9  (211) white prepupae new  (198) white prepupae 12hr  (269) white prepupae 24hr  (203) pupae 2d postWPP    81 pupae 3d postWPP    50 pupae 4d postWPP    70 adult male 01day    77 adult male 05day  102 adult male 30day  105 adult female 01day  (457) adult female 05day  (1253) adult female 30day  (1228) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1925) embryo 02-04hr    144 embryo 04-06hr    192 embryo 06-08hr    386 embryo 08-10hr    289 embryo 10-12hr    168 embryo 12-14hr    84 embryo 14-16hr    72 embryo 16-18hr    77 embryo 18-20hr    34 embryo 20-22hr    24 embryo 22-24hr    28 larva L1    95 larva L2    174 larva L3 12hr old    131 larva L3 puffstage 1-2    149 larva L3 puffstage 3-6    181 larva L3 puffstage 7-9    211 white prepupae new    198 white prepupae 12hr    269 white prepupae 24hr    203 pupae 2d postWPP    81 pupae 3d postWPP    50 pupae 4d postWPP    70 adult male 01day    77 adult male 05day    102 adult male 30day    105 adult female 01day    457 adult female 05day    1253 adult female 30day    1228 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1925 embryo 02-04hr    144 embryo 04-06hr    192 embryo 06-08hr    386 embryo 08-10hr    289 embryo 10-12hr    168 embryo 12-14hr    84 embryo 14-16hr    72 embryo 16-18hr    77 embryo 18-20hr    34 embryo 20-22hr    24 embryo 22-24hr    28 larva L1    95 larva L2    174 larva L3 12hr old    131 larva L3 puffstage 1-2    149 larva L3 puffstage 3-6    181 larva L3 puffstage 7-9    211 white prepupae new    198 white prepupae 12hr    269 white prepupae 24hr    203 pupae 2d postWPP    81 pupae 3d postWPP    50 pupae 4d postWPP    70 adult male 01day    77 adult male 05day    102 adult male 30day    105 adult female 01day    457 adult female 05day    1253 adult female 30day    1228 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1925 embryo 02-04hr    144 embryo 04-06hr    192 embryo 06-08hr    386 embryo 08-10hr    289 embryo 10-12hr    168 embryo 12-14hr    84 embryo 14-16hr    72 embryo 16-18hr    77 embryo 18-20hr    34 embryo 20-22hr    24 embryo 22-24hr    28 larva L1    95 larva L2    174 larva L3 12hr old    131 larva L3 puffstage 1-2    149 larva L3 puffstage 3-6    181 larva L3 puffstage 7-9    211 white prepupae new    198 white prepupae 12hr    269 white prepupae 24hr    203 pupae 2d postWPP    81 pupae 3d postWPP    50 pupae 4d postWPP    70 adult male 01day    77 adult male 05day    102 adult male 30day    105 adult female 01day    457 adult female 05day    1253 adult female 30day    1228 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0002899 expression level Developmental Stage   Expression Level embryo 00-02hr    1925 embryo 02-04hr    144 embryo 04-06hr    192 embryo 06-08hr    386 embryo 08-10hr    289 embryo 10-12hr    168 embryo 12-14hr    84 embryo 14-16hr    72 embryo 16-18hr    77 embryo 18-20hr    34 embryo 20-22hr    24 embryo 22-24hr    28 larva L1    95 larva L2    174 larva L3 12hr old    131 larva L3 puffstage 1-2    149 larva L3 puffstage 3-6    181 larva L3 puffstage 7-9    211 white prepupae new    198 white prepupae 12hr    269 white prepupae 24hr    203 pupae 2d postWPP    81 pupae 3d postWPP    50 pupae 4d postWPP    70 adult male 01day    77 adult male 05day    102 adult male 30day    105 adult female 01day    457 adult female 05day    1253 adult female 30day    1228 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1925) embryo 02-04hr  (144) embryo 04-06hr  (192) embryo 06-08hr  (386) embryo 08-10hr  (289) embryo 10-12hr  (168) embryo 12-14hr    84 embryo 14-16hr    72 embryo 16-18hr    77 embryo 18-20hr    34 embryo 20-22hr    24 embryo 22-24hr    28 larva L1    95 larva L2  (174) larva L3 12hr old  131 larva L3 puffstage 1-2  (149) larva L3 puffstage 3-6  (181) larva L3 puffstage 7-9  (211) white prepupae new  (198) white prepupae 12hr  (269) white prepupae 24hr  (203) pupae 2d postWPP    81 pupae 3d postWPP    50 pupae 4d postWPP    70 adult male 01day    77 adult male 05day  102 adult male 30day  105 adult female 01day  (457) adult female 05day  (1253) adult female 30day  (1228) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  1925 embryo 02-04hr    144 embryo 04-06hr    192 embryo 06-08hr    386 embryo 08-10hr    289 embryo 10-12hr    168 embryo 12-14hr    84 embryo 14-16hr    72 embryo 16-18hr    77 embryo 18-20hr    34 embryo 20-22hr    24 embryo 22-24hr    28 larva L1    95 larva L2    174 larva L3 12hr old    131 larva L3 puffstage 1-2    149 larva L3 puffstage 3-6    181 larva L3 puffstage 7-9    211 white prepupae new    198 white prepupae 12hr    269 white prepupae 24hr    203 pupae 2d postWPP    81 pupae 3d postWPP    50 pupae 4d postWPP    70 adult male 01day    77 adult male 05day    102 adult male 30day    105 adult female 01day    457 adult female 05day    1253 adult female 30day    1228 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1925 embryo 02-04hr    144 embryo 04-06hr    192 embryo 06-08hr    386 embryo 08-10hr    289 embryo 10-12hr    168 embryo 12-14hr    84 embryo 14-16hr    72 embryo 16-18hr    77 embryo 18-20hr    34 embryo 20-22hr    24 embryo 22-24hr    28 larva L1    95 larva L2    174 larva L3 12hr old    131 larva L3 puffstage 1-2    149 larva L3 puffstage 3-6    181 larva L3 puffstage 7-9    211 white prepupae new    198 white prepupae 12hr    269 white prepupae 24hr    203 pupae 2d postWPP    81 pupae 3d postWPP    50 pupae 4d postWPP    70 adult male 01day    77 adult male 05day    102 adult male 30day    105 adult female 01day    457 adult female 05day    1253 adult female 30day    1228 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1925 embryo 02-04hr    144 embryo 04-06hr    192 embryo 06-08hr    386 embryo 08-10hr    289 embryo 10-12hr    168 embryo 12-14hr    84 embryo 14-16hr    72 embryo 16-18hr    77 embryo 18-20hr    34 embryo 20-22hr    24 embryo 22-24hr    28 larva L1    95 larva L2    174 larva L3 12hr old    131 larva L3 puffstage 1-2    149 larva L3 puffstage 3-6    181 larva L3 puffstage 7-9    211 white prepupae new    198 white prepupae 12hr    269 white prepupae 24hr    203 pupae 2d postWPP    81 pupae 3d postWPP    50 pupae 4d postWPP    70 adult male 01day    77 adult male 05day    102 adult male 30day    105 adult female 01day    457 adult female 05day    1253 adult female 30day    1228 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0002899    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0002899 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0002899 expression level Tissue   Expression Level Larval Central Nervous System    60.15 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    22.5 Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head no informative data Adult Eye    3.825 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    4.275 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    166.2 Adult Testis    55.1 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    60.15 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    22.5 Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head no informative data Adult Eye    3.825 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    4.275 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    166.2 Adult Testis    55.1 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    60.15 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    22.5 Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head no informative data Adult Eye    3.825 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    4.275 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    166.2 Adult Testis    55.1 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    60.15 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    22.5 Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head no informative data Adult Eye    3.825 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    4.275 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    166.2 Adult Testis    55.1 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0002899 expression level Tissue   Expression Level Larval Central Nervous System    60.15 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    22.5 Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head no informative data Adult Eye    3.825 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    4.275 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    166.2 Adult Testis    55.1 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    60.15 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    22.5 Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head no informative data Adult Eye    3.825 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    4.275 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    166.2 Adult Testis    55.1 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    60.15 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    22.5 Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head no informative data Adult Eye    3.825 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    4.275 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    166.2 Adult Testis    55.1 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    60.15 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules    22.5 Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head no informative data Adult Eye    3.825 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    4.275 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    166.2 Adult Testis    55.1 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules     Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head no informative data Adult Eye     Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary     Adult Testis     Adult Male Accessory Gland no informative data Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    no informative data   NA  Eye    3.825   NA  Brain    no informative data   60.15  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    no informative data   NA  Crop    no informative data   no informative data  Midgut    no informative data   no informative data  Hindgut    no informative data   22.5  Malpighian Tubules    no informative data   no informative data  Fat Body    no informative data   no informative data  Salivary Gland    no informative data   NA  Heart    4.275   no informative data  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    166.2   NA  Testis    55.1   NA  Male Accessory Gland    no informative data   no informative data  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_13
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0002899 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7972-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable mus301KG09098 mus301ZIII-2205 mus301ZIII-2255 mus301ZIII-3198 mus301ZIII-3865 mus301ZIII-4875 mus301ZIII-5121 mus301ZIII-5813 mus301ZIII-6030 viable, with Scer\GAL4pnr-MD237 mus301GD12336 Sterility Allele fertile mus301KG09098 Other Phenotypes Allele chemical sensitive mus301094 mus301KG09098 mus301ZIII-2205 mus301ZIII-2255 mus301ZIII-3198 mus301ZIII-3865 mus301ZIII-4875 mus301ZIII-5121 mus301ZIII-5813 mus301ZIII-6030 chemical sensitive (with Df(3L)66C-G28) mus301094 mus301422 mus301660 chemical sensitive (with mus301094) mus301660 mus301D1 mus301D2 mus301D4 chemical sensitive (with mus301660) mus301094 chemical sensitive (with mus301D1) mus301094 chemical sensitive (with mus301D2) mus301094 chemical sensitive (with mus301D4) mus301094 chemical sensitive | recessive mus301D1 mus301D2 mus301D3 mus301D4 mus301D5 radiation sensitive mus301D1 Phenotype manifest in Allele chorion | maternal effect (with mus301094) mus301D4 chorion | maternal effect (with mus301D4) mus301094 dorsal appendage mus301094 egg | dorsal mus301094 egg | maternal effect (with Df(3L)66C-G28) mus301094 mus301422 mus301660 mus301D1 mus301D2 mus301D4 egg | maternal effect (with mus301094) mus301D1 egg | maternal effect (with mus301422) mus301D1 egg | maternal effect (with mus301660) mus301D1 egg | maternal effect (with mus301D1) mus301094 mus301422 mus301660 egg | maternal effect (with mus301D2) mus301D4 egg | maternal effect (with mus301D4) mus301D2 egg chamber mus301094 mus301422 mus301660 germline cyst mus301094 karyosome mus301094 mus301unspecified karyosome (with Df(3L)66C-G28) mus301094 mus301422 mus301660 mus301D1 mus301D2 mus301D4 karyosome (with mus301094) mus301D1 karyosome (with mus301422) mus301D1 karyosome (with mus301660) mus301D1 karyosome (with mus301D1) mus301094 mus301422 mus301660 karyosome (with mus301D2) mus301D4 karyosome (with mus301D4) mus301D2 nurse cell mus301094 oocyte mus301094 mus301660 oocyte (with Df(3L)66C-G28) mus301660 oocyte (with mus301D2) mus301D4 oocyte (with mus301D4) mus301D2 oocyte nucleus (with Df(3L)66C-G28) mus301094 mus301422 mus301660 mus301D1 mus301D2 mus301D4 oocyte nucleus (with mus301094) mus301D1 oocyte nucleus (with mus301422) mus301D1 oocyte nucleus (with mus301D1) mus301094 mus301422 oocyte nucleus (with mus301D2) mus301D4 oocyte nucleus (with mus301D4) mus301D2 synaptonemal complex mus301094
Classical Alleles ( 19 )
For All Classical Alleles Show
Allele of mus301 Class Mutagen Stocks Known lesion mus301D1 ethyl methanesulfonate 2 -- mus301D4 ethyl methanesulfonate 2 -- mus301660 antimorphic allele - genetic evidence, amorphic allele - genetic evidence ethyl methanesulfonate 1 Yes mus301c02271 piggyBac transposase 1 -- mus301D2 ethyl methanesulfonate 1 -- mus301D3 ethyl methanesulfonate 1 -- mus301KG09098 P-element activity 1 Yes mus301094 antimorphic allele - genetic evidence, amorphic allele - genetic evidence ethyl methanesulfonate 0 Yes mus301422 antimorphic allele - genetic evidence, amorphic allele - genetic evidence ethyl methanesulfonate 0 Yes mus301D5 ethyl methanesulfonate 0 -- mus301unspecified 0 -- mus301ZIII-2205 ethyl methanesulfonate 0 -- mus301ZIII-2255 ethyl methanesulfonate 0 Yes mus301ZIII-3198 ethyl methanesulfonate 0 Yes mus301ZIII-3865 ethyl methanesulfonate 0 -- mus301ZIII-4875 ethyl methanesulfonate 0 Yes mus301ZIII-5121 ethyl methanesulfonate 0 -- mus301ZIII-5813 ethyl methanesulfonate 0 -- mus301ZIII-6030 ethyl methanesulfonate 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of mus301 Class Mutagen Stocks Known lesion mus301GD12336 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes mus301+t6.2 in vitro construct - genomic fragment 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6112 (Ryder, 2004.4.26) Df(3L)pbl-X1 (Gonzalez-Reyes et al., 1997)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD12336} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{SUPor-P}mus301KG09098 NA PBac{PB}mus301c02271 NA
Gene Ontology: Function, Process & Cellular Component ( 15 unique terms )
Terms Based on Experimental Evidence ( 7 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
female meiosis chromosome segregation inferred from mutant phenotype (McCaffrey et al., 2006) germarium-derived oocyte fate determination inferred from genetic interaction with spn-A (Gonzalez-Reyes et al., 1997) inferred from mutant phenotype (McCaffrey et al., 2006) intracellular mRNA localization inferred from mutant phenotype (Gonzalez-Reyes et al., 1997) karyosome formation inferred from mutant phenotype (Gonzalez-Reyes et al., 1997, McCaffrey et al., 2006) oogenesis inferred from genetic interaction with fs(1)K10 (Gonzalez-Reyes et al., 1997) polarity specification of anterior/posterior axis inferred from mutant phenotype (Gonzalez-Reyes et al., 1997) polarity specification of dorsal/ventral axis inferred from mutant phenotype (Gonzalez-Reyes et al., 1997)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 10 terms )
Molecular Function
CV term Evidence References
ATP binding inferred from electronic annotation with InterPro:IPR001650, InterPro:IPR011545 (FlyBase Curators et al., 2004-) ATP-dependent helicase activity inferred from electronic annotation with InterPro:IPR011545 (FlyBase Curators et al., 2004-) helicase activity inferred from sequence or structural similarity (Lasko, 2000) nucleic acid binding inferred from electronic annotation with InterPro:IPR001650, InterPro:IPR011545 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
intracellular mRNA localization traceable author statement (Cooperstock and Lipshitz, 1997) oocyte differentiation non-traceable author statement (Deng and Lin, 2001) oogenesis traceable author statement (van Eeden and St. Johnston, 1999) regulation of translation traceable author statement (Cooperstock and Lipshitz, 1997)
Cellular Component
CV term Evidence References
small nuclear ribonucleoprotein complex inferred from sequence or structural similarity with EMBL:Z70200 (FlyBase, 1992-) U5 snRNP inferred from sequence or structural similarity with EMBL:Z70200 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions mus301 allele Gene References mus301094 mei-41 (Ghabrial and Schupbach, 1999, Masrouha et al., 2003) mei-W68 (Ghabrial and Schupbach, 1999) spn-E (Gonzalez-Reyes et al., 1997) mus301D4 mei-41 (Ghabrial and Schupbach, 1999) mei-W68 (Ghabrial and Schupbach, 1999) unspecified fs(1)K10 (Gonzalez-Reyes et al., 1997) lok (McCaffrey et al., 2006)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 64326 DroID - A comprehensive database of gene and protein interactions. • FBgn0002899 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38905
Orthologs
Genome-wide drosophilid orthologs	Dana\GF23962 Dere\GG14474 Dgri\GH16173 Dmoj\GI13326 Dper\GL22611 Dpse\GA20732 Dsec\GM25023 Dsim\GD14056 Dvir\GJ13152 Dwil\GK20010 Dyak\GE21661
Curated drosophilid orthologs	Dpse\GA20732
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL011649-PA Aedes aegypti (mosquito) AGAP012297-PA Anopheles gambiae (mosquito) XP_001943294.1 Acyrthosiphon pisum (pea aphid) 124688 Branchiostoma floridae (lancelet) 269990 Branchiostoma floridae (lancelet) XP_001892566.1 Brugia malayi (roundworm nematode) BGIBMGA013718-PA Bombyx mori (silk worm) ENSBTAP00000024158 Bos taurus (bovine) CBP36627 Caenorhabditis briggsae (nematode) CE27019 Caenorhabditis elegans (worm) ENSCAFP00000013398 Canis familiaris (dog) Chro.20448 Cryptosporidium hominis (obligate parasite) ENSCINP00000013046 Ciona intestinalis (sea squirt) JA13201 Caenorhabditis japonica (nematode) cgd2_4190 Cryptosporidium parvum (protozoan parasite) CPIJ010550 Culex pipens (mosquito) ENSCPOP00000008242 Cavia porcellus (guinea pig) 153772 Chlamidomonas reinhardtii (green alga) RP08296 Caenorhabditis remanei (nematode) ENSCSAVP00000012372 Ciona savignyi (sedentary tunicate) 161173 Capitella spl (polychaete worm) DDB0205039 Dictyostelium discoideum (amoeba) 320958 Daphnia pulex (daphnia) ENSDARP00000087601 Danio rerio (zebra fish) ENSECAP00000018314 Equus caballus (horse) XP_651740 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000001541 Gymnopilus aculeatus (mushroom) ENSGALP00000018252 Gallus gallus (chicken) GL50803_11384 Giardia lamblia (flagellated protozoan) 74949 Hypsipyla robusta (cedar shoot borer) ENSP00000295488 Homo sapiens (human) ISCW003708-PA Ixodes scapularis (deer tick) KLLA0D11462g Kluyveromyces lactis (yeast) LmjF23.1380 Leishmania major (virus) ENSMODP00000025985 Monodelphis domestica (gray opossum) ENSMMUP00000020129 Macaca mulatta (rhesus monkey) ENSMUSP00000041599 Mus musculus (house mouse) 94057 Nematostella vectensis (starlet anemone) ENSOANP00000003355 Ornithorynchus anatinus (platypus) 13772 Ostreococcus tauri (green alga) PHUM002465-PA Pediculus humanus (human body louse) ENSPPYP00000016635 Pongo pygmaeus (orangutan) ENSPTRP00000038909 Pan troglodytes (chimpanzee) PVX_085255 Plasmodium vivax (protozoal parasite) ENSRNOP00000002974 Rattus norvegicus (norway rat) Smp_019760 Schistosoma mansoni (trematode parasite) XP_001193582.1 Strongylocentrotus purpuratus (purple sea urchin) XP_973059.2 Tribolium castaneum (red flour beetle) Tc00.1047053509769.70 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000008380 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000047762 Takifugu rubripes (pufferfish Takifugu) 81757.m00152 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000003860 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV50316 LH13752 ISCW003708 FBgn0238910 FBgn0222007 FBgn0200379 FBgn0185750 FBgn0179884 JGI_V11_320958 FBgn0080723 FBgn0160202 FBgn0136083 FBgn0123644 FBgn0106733 FBgn0100956 CPIJ010550 CPIJ020174 BGIBMGA013718 ACYPI004507 GB30265 GB17855 AGAP012297 AAEL011649 PB25588 PHUM530580 GLEAN_01346
Stocks & Reagents
Stocks Listed in FlyBase ( 10 )
Bloomington	16477 y1; P{SUPor-P}mus301KG09098 ry506 916 st1 mus301D1/TM3, Sb1 Ser1 917 st1 mus301D2/TM3, Sb1 Ser1 918 st1 mus301D4/TM3, Sb1 Ser1 3328 Dp(1;Y)BS; ru1 mus301D3 st1 e1 ca1/TM3, Sb1
Harvard	- PBac{PB}mus301c02271
Kyoto	130002 st1 mus301D4/TM3, Sb1 106123 st1 mus301D1/TM3, Sb1 Ser1 106981 Dp(1;Y)BS; ru1 mus301660 st1 e1 ca1/TM3, Sb1
VDRC	v28072 w1118; P{GD12336}v28072
Genomic Clones ( 2 )
	BACR06E04 BACR09I19 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 10 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE48845
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LD37809 RE46304 RE50745
Other clones	EC052635 EC052641 EC052642 EC054112 EC054820 EC056404
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0002899 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38905
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: mus301 anon-WO0118547.354 (FlyBase, 1996-) Source for merge of: mus301 CG7972 (Laurencon et al., 2004) Source for merge of: mus301 spn-C (Ghabrial and Schupbach, 1999)
Additional comments	Source for merge of mus301 anon-WO0118547.354 was sequence comparison (date:051113). (FlyBase, 1996-)
Other Comments
	mus301 is involved in chromosome segregation in meiosis and in the repair of double-strand-DNA breaks in both meiotic and mitotic cells. (McCaffrey et al., 2006) Area matching Drosophila EST AI518328. (Davies, 2001.3.15) Analysis of mutants of the 5 spindle genes (spn-A, spn-B, mus301, spn-D and spn-E) reveals that the group of genes is required for each of the symmetry-breaking steps that generate polarity during axis formation. spn-E is required for the localisation of fs(1)K10, bcd and osk mRNAs, spn-A. spn-B, mus301 and spn-D play an indirect role in this process. (Gonzalez-Reyes et al., 1997) Analysis of egg chambers in mus301 mutants led to the conclusion that AP polarity within the oocyte is defined by the position of the oocyte in the egg chamber. (Gonzalez-Reyes and St. Johnston, 1994) Larval survival hypersensitive to exposure to X rays (Oliveri, Harris and Boyd, 1990), methyl methanesulfonate and nitrogen mustard. When fertile, homozygous females exhibit elevated frequencies of nondisjunction.
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_139921 RefSeq (Proteins) • NP_648178 DDBJ / EMBL / GenBank • AAF50481 AI518328 AX094230 BI361900 CL528247 CZ467820 Entrez Gene - A searchable database of RefSeq genes. • 38905 UniProtKB/TrEMBL • Q9VSE2
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Helicase, C-terminal (IPR001650) DNA/RNA helicase, DEAD/DEAH box type, N-terminal (IPR011545) DEAD-like helicase (IPR014001)
Linkouts
	BioGRID - A database of protein and genetic interactions • 64326 DroID - A comprehensive database of gene and protein interactions. • FBgn0002899 DRSC - Results from RNAi screens. • FBgn0002899 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0002899 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7972-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0002899 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38905 InParanoid A subset of ortholog calls from InParanoid. • AAEL011649-PA Aedes aegypti (mosquito) AGAP012297-PA Anopheles gambiae (mosquito) XP_001943294.1 Acyrthosiphon pisum (pea aphid) 124688 Branchiostoma floridae (lancelet) 269990 Branchiostoma floridae (lancelet) XP_001892566.1 Brugia malayi (roundworm nematode) BGIBMGA013718-PA Bombyx mori (silk worm) ENSBTAP00000024158 Bos taurus (bovine) CBP36627 Caenorhabditis briggsae (nematode) CE27019 Caenorhabditis elegans (worm) ENSCAFP00000013398 Canis familiaris (dog) Chro.20448 Cryptosporidium hominis (obligate parasite) ENSCINP00000013046 Ciona intestinalis (sea squirt) JA13201 Caenorhabditis japonica (nematode) cgd2_4190 Cryptosporidium parvum (protozoan parasite) CPIJ010550 Culex pipens (mosquito) ENSCPOP00000008242 Cavia porcellus (guinea pig) 153772 Chlamidomonas reinhardtii (green alga) RP08296 Caenorhabditis remanei (nematode) ENSCSAVP00000012372 Ciona savignyi (sedentary tunicate) 161173 Capitella spl (polychaete worm) DDB0205039 Dictyostelium discoideum (amoeba) 320958 Daphnia pulex (daphnia) ENSDARP00000087601 Danio rerio (zebra fish) ENSECAP00000018314 Equus caballus (horse) XP_651740 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000001541 Gymnopilus aculeatus (mushroom) ENSGALP00000018252 Gallus gallus (chicken) GL50803_11384 Giardia lamblia (flagellated protozoan) 74949 Hypsipyla robusta (cedar shoot borer) ENSP00000295488 Homo sapiens (human) ISCW003708-PA Ixodes scapularis (deer tick) KLLA0D11462g Kluyveromyces lactis (yeast) LmjF23.1380 Leishmania major (virus) ENSMODP00000025985 Monodelphis domestica (gray opossum) ENSMMUP00000020129 Macaca mulatta (rhesus monkey) ENSMUSP00000041599 Mus musculus (house mouse) 94057 Nematostella vectensis (starlet anemone) ENSOANP00000003355 Ornithorynchus anatinus (platypus) 13772 Ostreococcus tauri (green alga) PHUM002465-PA Pediculus humanus (human body louse) ENSPPYP00000016635 Pongo pygmaeus (orangutan) ENSPTRP00000038909 Pan troglodytes (chimpanzee) PVX_085255 Plasmodium vivax (protozoal parasite) ENSRNOP00000002974 Rattus norvegicus (norway rat) Smp_019760 Schistosoma mansoni (trematode parasite) XP_001193582.1 Strongylocentrotus purpuratus (purple sea urchin) XP_973059.2 Tribolium castaneum (red flour beetle) Tc00.1047053509769.70 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000008380 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000047762 Takifugu rubripes (pufferfish Takifugu) 81757.m00152 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000003860 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38905 modMine - Data generated by the modENCODE project. • FBgn0002899 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV50316 LH13752 ISCW003708 FBgn0238910 FBgn0222007 FBgn0200379 FBgn0185750 FBgn0179884 JGI_V11_320958 FBgn0080723 FBgn0160202 FBgn0136083 FBgn0123644 FBgn0106733 FBgn0100956 CPIJ010550 CPIJ020174 BGIBMGA013718 ACYPI004507 GB30265 GB17855 AGAP012297 AAEL011649 PB25588 PHUM530580 GLEAN_01346
Synonyms & Secondary IDs ( 12 )
Reported As
Symbol Synonym	anon-WO0118547.354   CG7972 (King et al., 2002.9.23, McCaffrey et al., 2006) cg7972 (Lasko, 2000) mus301 (McCaffrey et al., 2006, McCaffrey et al., 2006, Wei and Rong, 2007, Johnson-Schlitz et al., 2007, Wang et al., 2008, Cook et al., 2010.2.12) mus(3)301 (The Moscow Regional Drosophila melanogaster Stock Center, Dubna) spn-C (Huynh and St. Johnston, 2004, Abdu et al., 2003, Fanara et al., 2002, St. Johnston, 2001, Morris and Lehmann, 1999, Gonzalez-Reyes and St. Johnston, 1998, Deng and Bownes, 1998, Gonzalez-Reyes et al., 1997, Ray and Schupbach, 1996, Munn and Steward, 1995, Gavis, 1995, Roth et al., 1995, Anderson, 1995, Gonzalez-Reyes and St. Johnston, 1994, Tearle and Nusslein-Volhard, 1987, ) spnC (Deng and Lin, 2001, Masrouha et al., 2003, Johnstone and Lasko, 2001, Huynh and St. Johnston, 2000, Ghabrial et al., 1998, Lasko and Ashburner, 1990) SpnC (Lipshitz and Smibert, 2000, Johnson-Schlitz et al., 2007)
Name Synonym	mutagen-sensitive 301   spindel (Lehmann, 1995) spindle-C (Riechmann and Ephrussi, 2001, Cooperstock and Lipshitz, 1997, McCaffrey et al., 2006) spindle C
Secondary FlyBase IDs
	FBgn0003481 FBgn0035843 FBgn0062073
References ( 63 )
Generate a list of	All references relating to this gene ( 63 )
List References by type	Research paper  ( 23 ) Supplementary material  ( 2 ) Review  ( 18 ) Personal communication to FlyBase  ( 6 ) Abstract  ( 2 ) FlyBase analysis  ( 2 ) Stock list  ( 2 ) Patent  ( 1 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 3 ) Automatic genome annotation  ( 1 ) Curated genome annotation  ( 1 ) Book  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2010 Show research papers ...
Recent reviews (0)
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