FlyBase Gene Report: Dmel\mus301

General Information

Symbol

Dmel\mus301

Species

D. melanogaster

Name

mutagen-sensitive 301

Annotation Symbol

CG7972

Feature Type

protein_coding_gene

FlyBase ID

FBgn0002899

Gene Model Status

Current

Stock Availability

12 publicly available

Gene Snapshot

mutagen-sensitive 301 (mus301) encodes a member of the Mus308 subfamily of ATP-dependent helicases. It is involved in the repair of double-strand DNA breaks during recombination and in somatic cells, and in chromosome segregation. It contributes to dorsal-ventral patterning during oogenesis and posterior oocyte positioning. [Date last reviewed: 2019-03-14]

Other Summaries

Alliance
Auto summary
Red Book
Interactive Fly

Also Known As

spn-C, spnC, spindle-C

Key Links

Genomic Location

Cytogenetic map

66B8-66B8

Sequence location

3L:8,137,808..8,142,014 [+]

Recombination map

3-22

Sequence

Get Decorated FASTA

Genomic Maps

GBrowse JBrowse

Help me choose

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

[Detailed GO annotations]

Protein Family (UniProt)

Protein Signatures (InterPro)

Molecular Function (GO)
[Detailed GO annotations]

Experimental Evidence

Predictions / Assertions

ATP binding; helicase activity; nucleic acid binding

Summaries

Phenotypic Description (Red Book; Lindsley and Zimm 1992)

mus301 (J.B. Boyd)

Larval survival hypersensitive to exposure to X rays (Oliveri, Harris, and Boyd, 1990, Mutat. Res. 235: 25-31), methyl methanesulfonate, and nitrogen mustard. When fertile, homozygous females exhibit elevated frequencies of nondisjunction.

spn-C: spindle C

Maternal-effect lethal. Similar to spn-A.

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the GBrowse view of Dmel\mus301 or the JBrowse view of Dmel\mus301 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.45

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

mus301-RA

FBtr0076689

NM_139921

3364

1051

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

mus301-PA

FBpp0076412

117.3

1051

6.30

NP_648178

AAF50481

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Q9VSE2

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mus301 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

mus301_1

Linkouts

Gene Ontology (12 terms)

Molecular Function (3 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

ATP binding

inferred from electronic annotation with InterPro:IPR011545

(assigned by InterPro )

(FlyBase Curators et al., 2004-)

helicase activity

inferred from sequence or structural similarity

(Lasko, 2000)

nucleic acid binding

inferred from electronic annotation with InterPro:IPR011545

(assigned by InterPro )

(FlyBase Curators et al., 2004-)

Biological Process (9 terms)

Terms Based on Experimental Evidence (7 terms)

CV Term

Evidence

References

female meiosis chromosome segregation

inferred from mutant phenotype

(McCaffrey et al., 2006)

germarium-derived oocyte fate determination

inferred from mutant phenotype

(McCaffrey et al., 2006)

inferred from genetic interaction with FLYBASE:spn-A; FB:FBgn0003479

(Gonzalez-Reyes et al., 1997)

intracellular mRNA localization

inferred from mutant phenotype

(Gonzalez-Reyes et al., 1997)

oocyte karyosome formation

inferred from mutant phenotype

(McCaffrey et al., 2006, Gonzalez-Reyes et al., 1997)

oogenesis

inferred from genetic interaction with FLYBASE:fs(1)K10; FB:FBgn0000810

(Gonzalez-Reyes et al., 1997)

polarity specification of anterior/posterior axis

inferred from mutant phenotype

(Gonzalez-Reyes et al., 1997)

polarity specification of dorsal/ventral axis

inferred from mutant phenotype

(Gonzalez-Reyes et al., 1997)

Terms Based on Predictions or Assertions (4 terms)

CV Term

Evidence

References

intracellular mRNA localization

traceable author statement

(Cooperstock and Lipshitz, 1997)

maturation of SSU-rRNA

inferred from biological aspect of ancestor with PANTHER:PTN002774333

(assigned by GO_Central )

(Gaudet et al., 2011)

oogenesis

traceable author statement

(van Eeden and St. Johnston, 1999)

regulation of translation

traceable author statement

(Cooperstock and Lipshitz, 1997)

Cellular Component (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\mus301 in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\mus301

View exonic expression by tissue for Dmel\mus301

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0002899

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG7972-RA

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG7972

Flygut - An atlas of the Drosophila adult midgut

FBgn0002899

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, and Transgenic Constructs

Classical and Insertion Alleles ( 19 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 5 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of mus301

Transgenic constructs containing regulatory region of mus301

Deletions and Duplications ( 2 )

Disrupted in

Df(3L)Exel6112

(Ryder, 2004.4.26)

Df(3L)pbl-X1

(Gonzalez-Reyes et al., 1997)

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

mus301^GD12336

viable, with Scer\GAL4^Mef2.PR

mus301^GD12336

viable, with Scer\GAL4^pnr-MD237

mus301^GD12336

viable, with Scer\GAL4^tin.CΔ4

mus301^GD12336

Sterility

Allele

fertile

mus301^KG09098

Other Phenotypes

Allele

chemical sensitive

chemical sensitive (with Df(3L)66C-G28)

chemical sensitive (with mus301⁰⁹⁴)

chemical sensitive (with mus301⁶⁶⁰)

mus301⁰⁹⁴

chemical sensitive (with mus301^D1)

mus301⁰⁹⁴

chemical sensitive (with mus301^D2)

mus301⁰⁹⁴

chemical sensitive (with mus301^D4)

mus301⁰⁹⁴

chemical sensitive | recessive

decreased fecundity | female

mus301⁰⁹⁴

radiation sensitive

mus301^D1

short lived | heat sensitive, with Scer\GAL4^tin.CΔ4

mus301^GD12336

Phenotype manifest in

Allele

chorion | maternal effect (with mus301⁰⁹⁴)

mus301^D4

chorion | maternal effect (with mus301^D4)

mus301⁰⁹⁴

dorsal appendage

mus301⁰⁹⁴

egg | dorsal

mus301⁰⁹⁴

egg | maternal effect (with Df(3L)66C-G28)

egg | maternal effect (with mus301⁰⁹⁴)

mus301^D1

egg | maternal effect (with mus301⁴²²)

mus301^D1

egg | maternal effect (with mus301⁶⁶⁰)

mus301^D1

egg | maternal effect (with mus301^D1)

egg | maternal effect (with mus301^D2)

mus301^D4

egg | maternal effect (with mus301^D4)

mus301^D2

egg chamber

germline cyst

mus301⁰⁹⁴

karyosome

karyosome (with Df(3L)66C-G28)

karyosome (with mus301⁰⁹⁴)

mus301^D1

karyosome (with mus301⁴²²)

mus301^D1

karyosome (with mus301⁶⁶⁰)

mus301^D1

karyosome (with mus301^D1)

karyosome (with mus301^D2)

mus301^D4

karyosome (with mus301^D4)

mus301^D2

nurse cell

mus301⁰⁹⁴

oocyte

oocyte (with Df(3L)66C-G28)

mus301⁶⁶⁰

oocyte (with mus301^D2)

mus301^D4

oocyte (with mus301^D4)

mus301^D2

oocyte nucleus (with Df(3L)66C-G28)

oocyte nucleus (with mus301⁰⁹⁴)

mus301^D1

oocyte nucleus (with mus301⁴²²)

mus301^D1

oocyte nucleus (with mus301^D1)

oocyte nucleus (with mus301^D2)

mus301^D4

oocyte nucleus (with mus301^D4)

mus301^D2

synaptonemal complex

mus301⁰⁹⁴

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v7.1)

Homo sapiens (Human) (4)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\HELQ

14 of 15

Yes

Hsap\POLQ

2 of 15

Hsap\DDX60

1 of 15

Yes

Hsap\POLN

1 of 15

Model Organism Orthologs (via DIOPT v7.1)

Mus musculus (laboratory mouse) (3)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Helq

14 of 15

Yes

Mmus\Polq

2 of 15

Mmus\Poln

1 of 15

Rattus norvegicus (Norway rat) (3)

Rnor\Helq

12 of 13

Yes

Rnor\Polq

2 of 13

Rnor\Poln

1 of 13

Xenopus tropicalis (Western clawed frog) (2)

Xtro\helq

7 of 12

Yes

Xtro\polq

1 of 12

Danio rerio (Zebrafish) (2)

Drer\helq

12 of 15

Yes

Drer\polq

3 of 15

Caenorhabditis elegans (Nematode, roundworm) (3)

Cele\helq-1

12 of 15

Yes

Cele\polq-1

4 of 15

Cele\tbx-42

1 of 15

Arabidopsis thaliana (thale-cress) (1)

Atha\AT4G32700

2 of 9

Yes

Saccharomyces cerevisiae (Brewer's yeast) (1)

Scer\SLH1

1 of 15

Yes

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\SPAC23A1.19c

1 of 12

Yes

Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG091901J9 )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Dmel\mus301

Drosophila suzukii

Spotted wing Drosophila

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA20732

Drosophila persimilis

Dper\GL22611

Drosophila willistoni

Dwil\GK20010

Drosophila virilis

Dvir\GJ13152

Drosophila mojavensis

Dmoj\GI13326

Drosophila grimshawi

Dgri\GH16173

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915032P )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17015351

Glossina morsitans

Tsetse fly

Gmor\GMOY008033

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_05143

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_00624

Mayetiola destructor

Hessian fly

Mdes\Mdes005167

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL011649

Anopheles darlingi

American malaria mosquito

Adar\ADAC003918

Anopheles gambiae

Malaria mosquito

Agam\AGAP012297

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ020174

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ010550

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W03QE )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA013718

Danaus plexippus

Monarch butterfly

Dple\DPOGS204780-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL017693

Apis florea

Little honeybee

Aflo\2147684691

Apis mellifera

Western honey bee

Amel\GB48075

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP16750

Bombus terrestris

Buff-tailed bumblebee

Bter\15211881

Linepithema humile

Argentine ant

Lhum\LH13752

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:001dc7

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG014249

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_06823

Tribolium castaneum

Red flour beetle

Tcas\TC001346

Pediculus humanus

Human body louse

Phum\PHUM530580

Rhodnius prolixus

Kissing bug

Rpro\RPRC014077

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI004507

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_10984

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X03NG )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR004679

Ixodes scapularis

Black-legged tick

Isca\ISCW003708

Stegodyphus mimosarum

African social velvet spider

Smim\KFM57964.1

Tetranychus urticae

Two-spotted spider mite

Turt\tetur34g00860

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_320958

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G021D )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Hel308

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_017936gn

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000006332

Gallus gallus

Domestic chicken

Ggal\HELQ

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v7.1)

Drosophila melanogaster (Fruit fly) (34)

Gene Symbol

Score

Source

Alignment

4 of 10

abs

1 of 10

bel

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

Hlc

1 of 10

l(3)72Ab

1 of 10

mahe

1 of 10

me31B

1 of 10

obe

1 of 10

pit

1 of 10

Rm62

1 of 10

Rs1

1 of 10

vas

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

HELQ; helicase, POLQ like

14 of 15

606769

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

mus301

suppressible

mei-41

(Masrouha et al., 2003, Ghabrial and Schupbach, 1999)

mus301

suppressible

mei-W68

(Ghabrial and Schupbach, 1999)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

64326

DroID - A comprehensive database of gene and protein interactions.

FBgn0002899

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

38905

MIST (genetic) - An integrated Molecular Interaction Database

mus301

MIST (protein-protein) - An integrated Molecular Interaction Database

mus301

Pathways

Gene Group - Pathway Membership (FlyBase)

External Data

Linkouts

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-22

Cytogenetic map

66B8-66B8

Sequence location

3L:8,137,808..8,142,014 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

66B8-66B8

Limits computationally determined from genome sequence between P{PZ}l(3)07217⁰⁸²²³&P{EP}Rac2^EP3118 and P{lacW}Nmt^j1C7

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-22

(FlyBase, 2016)

3-19.0

(Comeron et al., 2012)

3-23

(Gonzalez-Reyes et al., 1997)

3-17

(Tearle and Nusslein-Volhard, 1987)

(Boyd et al., 1981)

Left of (cM)

P{lacW}l(3)S090314^S090314

(McCaffrey et al., 2006)

Right of (cM)

Notes

Stocks and Reagents

Stocks (12)

Bloomington

58299

y¹ v¹; P{TRiP.HMJ22406}attP40/CyO

16477

y¹; P{SUPor-P}mus301^KG09098 ry⁵⁰⁶

916

st¹ mus301^D1/TM3, Sb¹ Ser¹

917

st¹ mus301^D2/TM3, Sb¹ Ser¹

918

st¹ mus301^D4/TM3, Sb¹ Ser¹

3328

Dp(1;Y)B^S; ru¹ mus301^D3 st¹ e¹ ca¹/TM3, Sb¹

Harvard

c02271

PBac{PB}mus301^c02271

Kyoto

130002

st¹ mus301^D4/TM3, Sb¹

106123

st¹ mus301^D1/TM3, Sb¹ Ser¹

106981

Dp(1;Y)B^S; ru¹ mus301⁶⁶⁰ st¹ e¹ ca¹/TM3, Sb¹

VDRC

v28072

w¹¹¹⁸; P{GD12336}v28072

v318218

PBac{fTRG00732.sfGFP-TVPTBF}VK00033

Genomic Clones (17)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (10)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequences

BDGP DGC clones

RE48845

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0002899

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0002899

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

38905

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for database merge of

Source for merge of: mus301 spn-C

(Ghabrial and Schupbach, 1999)

Source for merge of: mus301 CG7972

(Laurencon et al., 2004)

Source for merge of: mus301 anon-WO0118547.354

(FlyBase, 1996-)

Additional comments

Source for merge of mus301 anon-WO0118547.354 was sequence comparison ( date:051113 ).

(FlyBase, 1996-)

Other Comments

mus301 is involved in chromosome segregation in meiosis and in the repair of double-strand-DNA breaks in both meiotic and mitotic cells.

(McCaffrey et al., 2006)

Area matching Drosophila EST AI518328.

(Davies, 2001.3.15)

Analysis of mutants of the 5 spindle genes (spn-A, spn-B, mus301, spn-D and spn-E) reveals that the group of genes is required for each of the symmetry-breaking steps that generate polarity during axis formation. spn-E is required for the localisation of fs(1)K10, bcd and osk mRNAs, spn-A. spn-B, mus301 and spn-D play an indirect role in this process.

(Gonzalez-Reyes et al., 1997)

Analysis of egg chambers in mus301 mutants led to the conclusion that AP polarity within the oocyte is defined by the position of the oocyte in the egg chamber.

(Gonzalez-Reyes and St. Johnston, 1994)

Larval survival hypersensitive to exposure to X rays (Oliveri, Harris and Boyd, 1990), methyl methanesulfonate and nitrogen mustard. When fertile, homozygous females exhibit elevated frequencies of nondisjunction.

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 31 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

38905

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

AAF50481

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Q9VSE2

Other crossreferences

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0002899

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

mus301_1

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG7972

Flygut - An atlas of the Drosophila adult midgut

FBgn0002899

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

38905

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC001346

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG7972

modMine - A data warehouse for the modENCODE project

FBgn0002899

Linkouts

BioGRID - A database of protein and genetic interactions.

64326

DroID - A comprehensive database of gene and protein interactions.

FBgn0002899

DRSC - Results frm RNAi screens

FBgn0002899

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0002899

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG7972-RA

FlyMine - An integrated database for Drosophila genomics

FBgn0002899

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

38905

MIST (genetic) - An integrated Molecular Interaction Database

mus301

MIST (protein-protein) - An integrated Molecular Interaction Database

mus301

Synonyms and Secondary IDs (13)

Reported As

Symbol Synonym

CG7972

(Ni et al., 2010.12.1, McCaffrey et al., 2006, King et al., 2002.9.23)

Mus301

(Siddiqui et al., 2012)

SpnC

(Johnson-Schlitz et al., 2007, Lipshitz and Smibert, 2000)

anon-WO0118547.354

cg7972

(Lasko, 2000)

mus(3)301

(The Moscow Regional Drosophila melanogaster Stock Center, Dubna)

mus301

(Merigliano et al., 2017, Sekelsky, 2017, Sarov et al., 2016, Luck et al., 2014, Japanese National Institute of Genetics, 2012.5.21, Cook et al., 2010.2.12, Wang et al., 2008, Johnson-Schlitz et al., 2007, Wei and Rong, 2007, McCaffrey et al., 2006, McCaffrey et al., 2006)

spn-C

(Huynh and St. Johnston, 2004, Abdu et al., 2003, Fanara et al., 2002, St. Johnston, 2001, Morris and Lehmann, 1999, Deng and Bownes, 1998, Gonzalez-Reyes and St. Johnston, 1998, Gonzalez-Reyes et al., 1997, Ray and Schupbach, 1996, Anderson, 1995, Gavis, 1995, Munn and Steward, 1995, Roth et al., 1995, Gonzalez-Reyes and St. Johnston, 1994, Tearle and Nusslein-Volhard, 1987)

spnC

(Masrouha et al., 2003, Deng and Lin, 2001, Johnstone and Lasko, 2001, Huynh and St. Johnston, 2000, Ghabrial et al., 1998, Lasko and Ashburner, 1990)

Name Synonyms

mutagen-sensitive 301

spindel

(Lehmann, 1995)

spindle C

spindle-C

(McCaffrey et al., 2006, Riechmann and Ephrussi, 2001, Cooperstock and Lipshitz, 1997)

Secondary FlyBase IDs

FBgn0003481
FBgn0035843
FBgn0062073

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

References (77)

Report Sections

Open Close