ATRIP, mus-304, ATR-interacting protein
Gene model reviewed during 5.46
There is only one protein coding transcript and one polypeptide associated with this gene
Interacts with ATR/mei-41.
The EEXXXDDL motif is required for the interaction with ATR/mei-41.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mus304 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\mus304 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of mus304 anon-WO0140519.82 was sequence comparison ( date:051113 ).
mus304 is required for a functional DNA damage checkpoint in the developing eye.
Gene is involved in post-replication recombination repair.
Larval survival hypersensitive to exposure to methyl methanesulfonate and nitrogen mustard. Neither hypermutable to alkylating agents nor defective in alkylation repair pathway; however, defective in UV-damage repair pathway (Smith and Dusenbery, 1988). When fertile, homozygous females exhibit uniformly decreased recombination along the X chromosome (Green, 1982). Partially deficient in post-replication repair (Boyd and Shaw, 1982) and excision (Boyd and Harris, 1981); DNA synthesis modified (Boyd and Shaw, 1982).