FB2019_06, released Dec 19, 2019

Gene: Dmel\odd

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General Information
Symbol
Dmel\odd
Species
D. melanogaster
Name
odd skipped
Annotation Symbol
CG3851
Feature Type
protein_coding_gene
FlyBase ID
FBgn0002985
Gene Model Status
Current
Stock Availability
23 publicly available
Gene Snapshot
In progress.Contributions welcome.
Other Summaries
Also Known As
l(2)01863
Key Links
Genomic Location
Cytogenetic map
24A1-24A1
Sequence location
2L:3,604,224..3,606,756 [-]
Recombination map
2-10
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Group (FlyBase)
Protein Family (UniProt)
Belongs to the Odd C2H2-type zinc-finger protein family. (P23803)
Protein Signatures (InterPro)
Molecular Function (GO)
[Detailed GO annotations]
Experimental Evidence
-
Predictions / Assertions
DNA binding; DNA-binding transcription factor activity; RNA polymerase II regulatory region sequence-specific DNA binding
Summaries
Gene Group (FlyBase)
C2H2 ZINC FINGER TRANSCRIPTION FACTORS -
Zinc finger C2H2 transcription factors are sequence-specific DNA binding proteins that regulate transcription. They possess DNA-binding domains that are formed from repeated Cys2His2 zinc finger motifs. (Adapted from PMID:1835093, FBrf0220103 and FBrf0155739).
Protein Function (UniProtKB)
Pair-rule protein that determines both the size and polarity of even-numbered as well as odd-numbered parasegments during embryogenesis. DNA-binding transcription factor that acts primarily as a transcriptional repressor but can also function as a transcriptional activator, depending on the stage of development and spatial restrictions. May function redundantly with odd and drm in leg joint formation during the larval stages, acting downstream of Notch activation.
(UniProt, P23803)
Phenotypic Description (Red Book; Lindsley and Zimm 1992)
odd: odd skipped
Embryonic lethal; posterior part of the denticle band and adjacent naked cuticle replaced by mirror-image duplication of the anterior part of the denticle band and adjacent naked cuticle in T2, A1, A3, A5, and A7. Pole-cell-transplantation experiments indicate that odd+ not maternally required. Positional expression of ftz unaffected (Carrol and Scott, 1986, Cell 54: 113-26). However, stripes of en expression are broader than normal in even-numbered, but of normal width in odd-numbered parasegments; Ubx expression is consequently low in broader-than-normal stripes in even-numbered parasegments (Martinez-Arias and White, 1988, Development 102: 325-38).
Summary (Interactive Fly)
transcription factor - zinc finger - pair rule gene - mutants associated with cuticle defects that are limited to alternate--odd-numbered--segments - labels a group of distinct neurons associated with the mushroom body and optic lobe in the adult brain
Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the GBrowse view of Dmel\odd or the JBrowse view of Dmel\odd for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model
Gene model reviewed during 5.49
Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
odd-RA
FBtr0077557
NM_164546
2347
392
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
odd-PA
FBpp0077246
44.6
392
8.66
NP_722922
AAF51085
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)
392 (aa); 45 (kD predicted)
(Coulter et al., 1990)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\odd using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Gene Ontology (16 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
DNA binding
non-traceable author statement
(assigned by UniProt )
(Coulter et al., 1990)
DNA-binding transcription factor activity
inferred from sequence or structural similarity
(Coulter et al., 1990)
RNA polymerase II regulatory region sequence-specific DNA binding
inferred from biological aspect of ancestor with PANTHER:PTN000367524
(assigned by GO_Central )
(Gaudet et al., 2011)
Biological Process (12 terms)
Terms Based on Experimental Evidence (9 terms)
CV Term
Evidence
References
blastoderm segmentation
inferred from mutant phenotype
(assigned by UniProt )
(Coulter et al., 1990)
imaginal disc-derived leg joint morphogenesis
inferred from mutant phenotype
(Hao et al., 2003)
Malpighian tubule morphogenesis
inferred from mutant phenotype
(assigned by UniProt )
(Tena et al., 2007)
negative regulation of transcription by RNA polymerase II
inferred from mutant phenotype
(assigned by UniProt )
(Mullen and DiNardo, 1995)
inferred from direct assay
(Bouchard et al., 2000)
inferred from direct assay
(assigned by UniProt )
(Saulier-Le Drean et al., 1998)
negative regulation of transcription, DNA-templated
inferred from direct assay
(assigned by UniProt )
(Saulier-Le Drean et al., 1998)
pattern specification process
inferred from mutant phenotype
(assigned by CACAO )
(Schroeder et al., 2011)
periodic partitioning by pair rule gene
inferred from mutant phenotype
(assigned by UniProt )
(Mullen and DiNardo, 1995)
positive regulation of transcription by RNA polymerase II
inferred from direct assay
(assigned by UniProt )
(Saulier-Le Drean et al., 1998)
positive regulation of transcription, DNA-templated
inferred from direct assay
(assigned by UniProt )
(Saulier-Le Drean et al., 1998)
Terms Based on Predictions or Assertions (6 terms)
CV Term
Evidence
References
embryonic hindgut morphogenesis
inferred from biological aspect of ancestor with PANTHER:PTN002306374
(assigned by GO_Central )
(Gaudet et al., 2011)
embryonic pattern specification
inferred from biological aspect of ancestor with PANTHER:PTN002306374
(assigned by GO_Central )
(Gaudet et al., 2011)
imaginal disc-derived leg joint morphogenesis
inferred from biological aspect of ancestor with PANTHER:PTN002306374
(assigned by GO_Central )
(Gaudet et al., 2011)
negative regulation of transcription by RNA polymerase II
inferred from biological aspect of ancestor with PANTHER:PTN000367524
(assigned by GO_Central )
(Gaudet et al., 2011)
positive regulation of transcription by RNA polymerase II
inferred from biological aspect of ancestor with PANTHER:PTN000367524
(assigned by GO_Central )
(Gaudet et al., 2011)
regulation of transcription by RNA polymerase II
inferred from sequence or structural similarity
(Coulter et al., 1990)
Cellular Component (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
nucleus
inferred from sequence or structural similarity
(Coulter et al., 1990)
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
pupal stage
leg | restricted
(Hao et al., 2003)
third instar larval stage
ventral thoracic disc | restricted
(Hao et al., 2003)
embryonic stage 6 -- 17
organism | segment polarity expression pattern
(Hart et al., 1996)
embryonic stage 5
organism | 90-100% egg length

Comment: 85-100% egg length

(Hart et al., 1996)
organism | pair rule expression pattern
(Schroeder et al., 2011, Berman et al., 2004, Hart et al., 1996)
embryonic stage
epithelial cell

Comment: diffuse apical distribution

(Lecuyer et al., 2007)
epithelium
(Lecuyer et al., 2007)
neuroblast

Comment: asymetrically distributed

(Lecuyer et al., 2007)
embryonic stage 4
epithelial cell
(Lecuyer et al., 2007)
epithelium
(Lecuyer et al., 2007)
embryonic stage 11
neuroblast MP2
(Chang et al., 2000)
MP1 neuron
(Wheeler et al., 2006)
organism | striped
(Biehs et al., 2010)
foregut primordium
(Biehs et al., 2010)
embryonic stage 4 -- 6
central brain anlage in statu nascendi
(Fisher et al., 2012)
dorsal ectoderm anlage

Comment: anlage in statu nascendi

(Fisher et al., 2012)
foregut anlage in statu nascendi
(Fisher et al., 2012)
mesectoderm anlage

Comment: anlage in statu nascendi

(Fisher et al., 2012)
mesoderm anlage

Comment: anlage in statu nascendi

(Fisher et al., 2012)
organism | segmentally repeated
(Fisher et al., 2012)
ventral ectoderm anlage

Comment: anlage in statu nascendi

(Fisher et al., 2012)
antennal anlage in statu nascendi

Comment: reported as procephalic ectoderm anlage in statu nascendi

(Fisher et al., 2012)
dorsal head epidermis anlage in statu nascendi

Comment: reported as procephalic ectoderm anlage in statu nascendi

(Fisher et al., 2012)
visual anlage in statu nascendi

Comment: reported as procephalic ectoderm anlage in statu nascendi

(Fisher et al., 2012)
embryonic stage 7 -- 8
antennal anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)
central brain anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)
dorsal head epidermis anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)
visual anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)
dorsal ectoderm
(Fisher et al., 2012)
foregut anlage
(Fisher et al., 2012)
organism | segmentally repeated
(Fisher et al., 2012)
trunk mesoderm
(Fisher et al., 2012)
ventral ectoderm
(Fisher et al., 2012)
embryonic stage 9 -- 10
antennal primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
central brain primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
visual primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
dorsal head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
lateral head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
ventral head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
dorsal ectoderm
(Fisher et al., 2012)
foregut primordium
(Fisher et al., 2012)
mesectoderm
(Fisher et al., 2012)
trunk mesoderm
(Fisher et al., 2012)
ventral ectoderm
(Fisher et al., 2012)
embryonic stage 11 -- 12
atrium | precursor

Comment: reported as atrium primordium

(Fisher et al., 2012)
cardiogenic mesoderm
(Fisher et al., 2012)
clypeo-labral primordium
(Fisher et al., 2012)
dorsal apodeme anlage
(Fisher et al., 2012)
dorsal epidermis primordium
(Fisher et al., 2012)
fat body/gonad primordium
(Fisher et al., 2012)
foregut primordium
(Fisher et al., 2012)
labral sensory complex primordium
(Fisher et al., 2012)
lymph gland primordium

Comment: reported as lymph gland specific anlage

(Fisher et al., 2012)
Malpighian tubule primordium
(Fisher et al., 2012)
pericardial cell primordium

Comment: reported as pericardial cell specific anlage

(Fisher et al., 2012)
proventriculus primordium
(Fisher et al., 2012)
ventral epidermis primordium
(Fisher et al., 2012)
embryonic stage 13 -- 16
atrium
(Fisher et al., 2012)
embryonic dorsal apodeme
(Fisher et al., 2012)
embryonic dorsal epidermis
(Fisher et al., 2012)
embryonic foregut
(Fisher et al., 2012)
embryonic hindgut
(Fisher et al., 2012)
embryonic proventriculus
(Fisher et al., 2012)
embryonic proventriculus inner layer
(Fisher et al., 2012)
embryonic ventral apodeme
(Fisher et al., 2012)
embryonic ventral epidermis
(Fisher et al., 2012)
embryonic/larval dorsal vessel
(Fisher et al., 2012)
embryonic/larval fat body
(Fisher et al., 2012)
embryonic/larval lymph gland
(Fisher et al., 2012)
embryonic/larval pericardial cell
(Fisher et al., 2012)
ventral midline
(Fisher et al., 2012)
median neuroblast MNB interneuron
(Kearney et al., 2004)
MP1 neuron
(Kearney et al., 2004)
late embryonic stage
embryonic/larval brain
(Hart et al., 1996)
embryonic/larval garland cell
(Hart et al., 1996)
embryonic/larval Malpighian tubule
(Hart et al., 1996)
embryonic/larval proventriculus
(Hart et al., 1996)
pharyngeal muscle
(Hart et al., 1996)
pericardial cell
(Hart et al., 1996)
ventral nerve cord
(Hart et al., 1996)
embryonic stage 9
midline primordium

Comment: rows A, B

(Wheeler et al., 2006)
embryonic stage 13
MP1 neuron
(Wheeler et al., 2006)
embryonic stage 17
MP1 neuron
(Wheeler et al., 2006)
embryonic stage 5 -- 6
mesectoderm
(Kearney et al., 2004)
embryonic stage 9 -- 12
midline primordium | subset
(Kearney et al., 2004)
radioisotope in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 6 -- 9
organism | segment polarity expression pattern
(Coulter et al., 1990)
embryonic stage 5
organism | pair rule expression pattern
(Coulter et al., 1990)
embryonic stage 4
organism | 60% egg length

Comment: 62% egg length

(Coulter et al., 1990)
RT-PCR
Stage
Tissue/Position (including subcellular localization)
Reference
larval stage
embryonic/larval lymph gland
(Gao et al., 2011)
Additional Descriptive Data
Expression was examined at four phases of embryonic stage 5. The striped pattern becomes visible in phase 1 (0-5'), all stripes except stripe 7 are expressed during phase 2 (5-17'), and their spacing and expression levels become largely uniform by phase 3 (17-30'). The stripes initially appear less clearly separated and more graded.
(Schroeder et al., 2011)
In stage 11 embryos, odd is expressed in stripes that are adjacent and posterior to hh-expressing cells in each parasegment. It is also expressed in the presumptive foregut.
(Biehs et al., 2010)
Expression assayed at stages 9, 11, 13, and 17. Expression may be continuous between assayed stages in some tissues.
(Wheeler et al., 2006)
The odd, sob and drm transcripts are detected an identical pattern in the third instar leg disc. There is segmental expression manifested as concentric rings on the distal edges of each presumptive leg segment not including the 4 tarsal segments (i.e. 5 rings of expression). There is an additional area of expression in the center of the disc that may correspond to a track of glial cells. The expression of drm is observed to begin during early larval development as a proximal ring of expression corresponding to the coxa. As larval development proceeds additional rings of expression are observed until the full complement of five rings is observed. Expression of odd, sob and drm occur in cells that are adjacent and distal to cells expressing the N ligands, Dl and Ser.
(Hao et al., 2003)
At the cellular blastoderm stage, odd transcripts accumulate in 7 transverse stripes that are 3-4 cells wide and correspond to the odd-numbered segments. A domain of expression is also observed at 85-100% egg length. At around the time of gastrulation, the stripe pattern changes to a segment polarity pattern of 14 stripes. The odd stripes are strongest in the blastoderm stage and diminish intensity when they are expressed in the segment polarity pattern. The odd expression pattern overlaps that of sob at these stages. In later stages, odd continues to be expressed in the epidermis but is also expressed in the proventriculus, proximal Malpighian tubules, brain, pharyngeal muscles, ventral nerve cord, pericardial cells, and garland cells.
(Hart et al., 1996)
odd transcription is repressed by ectopic eve protein in evehs.PS embryos. Timing suggests that eve is a direct regulator of odd.
(Manoukian and Krause, 1992)
odd transcripts are first detected in the syncytial blastoderm in a 5 cell wide stripe at 62% egg length. During cellularization, the pattern evolves into one of six regular stripes of ~3-4 cell widths. There is a noticeable posterior and dorsal lag in the generation of these stripes. A non-periodic anterior domain of expression is also observed which persists through subsequent stages. Labelling with ftz indicates that the resolution of the odd pattern into six stripes is coincident with the appearance of the seven stripe ftz pattern. A 7th posteriormost odd stripe appears at 15% egg length after nuclear elongation but before the completion of cellularization. During gastrulation, this pattern evolves into a pattern in which odd is expressed in homologous portions of each segment. This occurs through the narrowing of the original seven stripes and the appearance of 8 new stripes. Results of labelling with en suggest that each of the seven odd stripes lies posterior to an even-numbered en stripe.
(Coulter et al., 1990)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
distribution deduced from reporter
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 10 -- 11
neuroblast MP2
(Kim et al., 2007)
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 15 -- 16
embryonic/larval lymph gland
(Perrin et al., 2004)
embryonic pericardial cell
(Perrin et al., 2004)
embryonic stage 11 -- 13
cell | subset of salivary gland duct primordium
(Ward and Coulter, 2000)
embryonic stage 16
embryonic salivary gland duct | surrounding

Comment: a ring of cells about midway along the length of the duct

(Ward and Coulter, 2000)
embryonic/larval pharynx
(Ward and Coulter, 2000)
embryonic/larval Malpighian tubule | proximal
(Ward and Coulter, 2000)
embryonic/larval dorsal vessel
(Ward and Coulter, 2000)
embryonic/larval lymph gland
(Gao et al., 2011, Sinenko et al., 2009)
embryonic stage 11 -- 16
embryonic/larval proventriculus outer layer
(Ward and Coulter, 2000)
embryonic/larval posterior midgut
(Ward and Coulter, 2000)
embryonic/larval garland cell
(Ward and Coulter, 2000)
neuroblast of ventral nerve cord primordium | segmentally repeated | subset
(Ward and Coulter, 2000)
embryonic stage 12 -- 16
stomodeum
(Ward and Coulter, 2000)
embryonic/larval lymph gland
(Ward and Coulter, 2000)
embryonic stage 13 -- 16
embryonic/larval pericardial cell
(Ward and Coulter, 2000)
embryonic stage 11 -- 17
embryonic brain | restricted

Comment: 3 distinct clusters

(Ward and Coulter, 2000)
embryonic stage 9
midline glial cell | subset

Comment: transiently expressed

(Ward and Coulter, 2000)
embryonic stage 11
midline glial cell | subset

Comment: transiently expressed

(Ward and Coulter, 2000)
embryonic stage 15 -- 17
embryonic/larval pericardial cell | subset
• nucleus

Comment: odd-expressing subset

(Ward and Skeath, 2000)
embryonic/larval lymph gland
• nucleus
(Ward and Skeath, 2000)
third instar larval stage
embryonic/larval pericardial cell
(Das et al., 2008)
embryonic/larval lymph gland
(Frandsen et al., 2008)
medullary zone of lymph gland primary lobe
(Gao et al., 2011)
prohemocyte
(Gao et al., 2011)
embryonic stage 14 -- 15
lymph gland primordium
(Sinenko et al., 2009)
embryonic stage 17
dMP2 Ilp7 neuron of abdominal segment 6
(Miguel-Aliaga et al., 2008)
dMP2 Ilp7 neuron of abdominal segment 7
(Miguel-Aliaga et al., 2008)
dMP2 Ilp7 neuron of abdominal segment 8
(Miguel-Aliaga et al., 2008)
dMP2 Ilp7 neuron of abdominal segment 9
(Miguel-Aliaga et al., 2008)
embryonic stage
embryonic/larval dMP2 Ilp7 neuron
(Castellanos et al., 2013)
embryonic stage 13
embryonic/larval pericardial cell
(Frandsen et al., 2008)
embryonic/larval lymph gland
(Frandsen et al., 2008)
adult stage
adult odd neuron of the calyx
(Levy and Larsen, 2013)
adult odd neuron of the central brain
(Levy and Larsen, 2013)
adult odd neuron of the lobula plate
(Levy and Larsen, 2013)
adult glial cell | subset
(Levy and Larsen, 2013)
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 17
dMP2 neuron
(Liu and Bossing, 2016)
MP1 neuron
(Liu and Bossing, 2016)
Additional Descriptive Data
Around 90% of odd positive adult neurons are positive for Scer\GAL4ChAT.7.4.
(Levy and Larsen, 2013)
In early third instar larvae, the highest levels of odd are observed in medullary zone prohemocytes in the lymph gland. At this time odd is downregulated in terminally differentiated plasmatocytes. This epression pattern is maintained until the late-third larval instar. odd is expressed in prohemocytes throughout lymph gland development and maturation and is downregulated as pro-hemocytes differentiate.
(Gao et al., 2011)
odd protein is expressed in the embryonic lymph gland.
(Sinenko et al., 2009)
Expression is observed in A6 to A9 dMP2 neurons.
(Miguel-Aliaga et al., 2008)
odd protein is expressed in the developing embryonic brain from embryonic stage 11, and is expressed in three discrete clusters at the end of embryogenesis. It is also expressed in a few neuroblasts and neurons per segment in the ventral nerve cord. odd protein is transiently expressed in a small subset of midline glial cells at embryonic stage 9. At embryonic stage 16, odd protein is expressed in a ring of cells encircling the salivary gland duct about midway along its length. This ring is derived from six odd-positive cells in the ventral epidermis of parasegment 2 at embryonic stage 11; these cells reorganize to form a cluster by stage 12, then migrate anteriorly and dorsally to their final position.
(Ward and Coulter, 2000)
odd protein is expressed in two rows of mesodermal cells flanking the dorsal midline of late stage embryos. These cells are physically close to, and flank, the cardioblasts. Pericardial cells expressing odd protein do not express either eve or tin, which are expressed in all previously identified pericardial cells; they do however also express zfh1. odd-expressing pericardial cells lie lateral to tin-expressing pericardial cells
(Ward and Skeath, 2000)
Marker for
 
embryonic pericardial cell
(Albrecht et al., 2006)
embryonic/larval garland cell
(Ward and Coulter, 2000)
embryonic/larval lymph gland
(Lo et al., 2007, Albrecht et al., 2006, Perrin et al., 2004, Ward and Coulter, 2000)
embryonic/larval pericardial cell
(Lo et al., 2007, Ward and Coulter, 2000)
lymph gland primordium
(Sinenko et al., 2009)
neuroblast MP2
(Kim et al., 2007)
pericardial cell
(Mirzoyan and Pandur, 2013)
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
Reporter: P{GAL4}oddMC
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
lobula plate tangential neuron Hx
(Wasserman et al., 2015)
adult odd neuron of the calyx
(Levy and Larsen, 2013)
adult odd neuron of the central brain
(Levy and Larsen, 2013)
adult odd neuron of the lobula plate
(Levy and Larsen, 2013)
adult glial cell | subset
(Levy and Larsen, 2013)
third instar larval stage
larval odd neuron of the inferior protocerebrum
(Slater et al., 2015, Levy and Larsen, 2013)
larval odd neuron of the calyx
(Slater et al., 2015)
second instar larval stage
larval odd neuron of the calyx
(Slater et al., 2015, Levy and Larsen, 2013)
larval odd neuron of the inferior protocerebrum
(Slater et al., 2015)
prepupal stage P1 -- pharate adult stage P15
adult odd neuron of the calyx
(Levy and Larsen, 2013)
adult odd neuron of the central brain
(Levy and Larsen, 2013)
adult odd neuron of the lobula plate
(Levy and Larsen, 2013)
embryonic stage 15
neuroblast DPL | subset
(Levy and Larsen, 2013)
mushroom body neuroblast
(Levy and Larsen, 2013)
neuroblast BLP | subset
(Levy and Larsen, 2013)
Reporter: P{lacZ}oddrK111
Stage
Tissue/Position (including subcellular localization)
Reference
pupal stage
apodeme of leg
(Mirth and Akam, 2002)
joint
(Mirth and Akam, 2002)
leg | restricted
(Mirth and Akam, 2002)
larval stage
ventral thoracic disc | restricted
(Mirth and Akam, 2002)
third instar larval stage
ventral thoracic disc | restricted
(Rauskolb and Irvine, 1999)
antennal disc | restricted

Comment: two rings plus maxillary palp stripe

(Brás-Pereira and Casares, 2008)
(Levy and Larsen, 2013)
adult stage
adult odd neuron of the calyx
(Levy and Larsen, 2013)
adult odd neuron of the central brain
(Levy and Larsen, 2013)
adult odd neuron of the lobula plate
(Levy and Larsen, 2013)
adult glial cell | subset
(Levy and Larsen, 2013)
second instar larval stage
larval odd neuron of the calyx
(Slater et al., 2015)
larval odd neuron of the inferior protocerebrum
(Slater et al., 2015)
prepupal stage P3 -- P4
joint
(Turchyn et al., 2011)
Reporter: P{PT1}odd106
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult odd neuron of the calyx
(Levy and Larsen, 2013)
adult odd neuron of the central brain
(Levy and Larsen, 2013)
adult odd neuron of the lobula plate
(Levy and Larsen, 2013)
adult glial cell | subset
(Levy and Larsen, 2013)
embryonic stage 10 -- 17
dMP2 Ilp7 neuron of abdominal segment 6
(Miguel-Aliaga et al., 2008)
dMP2 Ilp7 neuron of abdominal segment 7
(Miguel-Aliaga et al., 2008)
dMP2 Ilp7 neuron of abdominal segment 8
(Miguel-Aliaga et al., 2008)
dMP2 Ilp7 neuron of abdominal segment 9
(Miguel-Aliaga et al., 2008)
embryonic stage 17
MP1 neuron
(Miguel-Aliaga et al., 2008)
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\odd in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 1-3
  • Stages(s) 4-6
  • Stages(s) 7-8
  • Stages(s) 9-10
  • Stages(s) 11-12
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 25 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 13 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of odd
Transgenic constructs containing regulatory region of odd
Deletions and Duplications ( 12 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal | male limited, with Scer\GAL4Bx-MS1096
lethal | male limited | cold sensitive, with Scer\GAL4Bx-MS1096
lethal | recessive
lethal - all die before end of embryonic stage
lethal - all die before end of embryonic stage | recessive
partially lethal - majority die
partially lethal - majority die, with Scer\GAL4da.G32
partially lethal - majority die, with Scer\GAL4en-e16E
viable (with odd4)
viable (with oddhd1rv1)
viable (with oddhd1rv2)
viable (with oddhd1rv3)
viable (with oddhd1rv4)
viable (with oddhd1rv5)
viable (with oddhd1rv9)
viable (with oddhd1rv10)
viable (with oddhd1rv11)
Other Phenotypes
Allele
pair rule phenotype
pair rule phenotype | embryonic stage | recessive
segment polarity phenotype | embryonic stage 12
some die during embryonic stage
some die during embryonic stage | recessive
visible, with Scer\GAL4da.G32
visible, with Scer\GAL4en-e16E
visible, with Scer\GAL4pnr-MD237
visible, with Scer\GAL4ptc-559.1
visible | female limited, with Scer\GAL4Bx-MS1096
visible | female limited | cold sensitive, with Scer\GAL4Bx-MS1096
visible | somatic clone, with Scer\GAL4Act5C.PI
Phenotype manifest in
Allele
abdominal 1 ventral denticle belt
abdominal 1 ventral denticle belt | larval stage
abdominal 3 ventral denticle belt
abdominal 3 ventral denticle belt | larval stage
abdominal 5 ventral denticle belt
abdominal 5 ventral denticle belt | larval stage
abdominal 7 ventral denticle belt
abdominal 7 ventral denticle belt | larval stage
abdominal 9 ventral denticle belt | larval stage
abdominal segment 1 & embryonic epidermis
abdominal segment 3 & embryonic epidermis
abdominal segment 5 & embryonic epidermis
abdominal segment 7 & embryonic epidermis
adult thorax, with Scer\GAL4da.G32
adult thorax, with Scer\GAL4en-e16E
adult thorax, with Scer\GAL4pnr-MD237
apodeme | embryonic stage
dental sclerite
denticle belt
embryonic/first instar larval cuticle
embryonic abdominal segment 1 | anterior
embryonic abdominal segment 3 | anterior
embryonic abdominal segment 5 | anterior
embryonic abdominal segment 7 | anterior
embryonic head
embryonic labial segment
embryonic maxillary segment
embryonic segment
leg & adult cuticle, with Scer\GAL4ptc-559.1
leg & adult cuticle | somatic clone, with Scer\GAL4Act5C.PI
mesothoracic segment & embryonic epidermis
mesothoracic ventral denticle belt
metatarsus | somatic clone
mouth hooks
pretarsus | somatic clone
pupal thorax, with Scer\GAL4da.G32
segment
tarsal segment 2 | somatic clone
tarsal segment 3 | somatic clone
tarsal segment 4 | somatic clone
tarsal segment | somatic clone
ventral thoracic disc, with Scer\GAL4ptc-559.1
wing | female limited, with Scer\GAL4Bx-MS1096
wing | female limited | cold sensitive, with Scer\GAL4Bx-MS1096
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v7.1)
Homo sapiens (Human) (9)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\OSR1
5 of 15
Yes
No
Hsap\OSR2
4 of 15
No
No
Hsap\EGR1
1 of 15
No
No
Hsap\EGR2
1 of 15
No
No
Hsap\EGR3
1 of 15
No
No
Hsap\EGR4
1 of 15
No
No
Hsap\KLF11
1 of 15
No
No
Hsap\KLF15
1 of 15
No
No
 
Hsap\SP2
1 of 15
No
No
Model Organism Orthologs (via DIOPT v7.1)
Mus musculus (laboratory mouse) (8)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Osr1
5 of 15
Yes
No
Mmus\Osr2
3 of 15
No
No
Mmus\Egr1
1 of 15
No
No
Mmus\Egr3
1 of 15
No
No
Mmus\Egr4
1 of 15
No
No
Mmus\Klf11
1 of 15
No
No
Mmus\Klf15
1 of 15
No
No
Mmus\Sp2
1 of 15
No
No
Rattus norvegicus (Norway rat) (2)
Rnor\Osr1
4 of 13
Yes
No
Rnor\Osr2
4 of 13
Yes
No
Xenopus tropicalis (Western clawed frog) (8)
Xtro\osr1
3 of 12
Yes
No
Xtro\osr2
3 of 12
Yes
No
Xtro\egr1
1 of 12
No
No
Xtro\egr2
1 of 12
No
No
Xtro\egr3
1 of 12
No
No
Xtro\klf11
1 of 12
No
No
Xtro\klf15
1 of 12
No
No
Xtro\sp2
1 of 12
No
Yes
Danio rerio (Zebrafish) (9)
Drer\osr1
5 of 15
Yes
No
Drer\osr2
4 of 15
No
No
Drer\egr1
1 of 15
No
No
Drer\egr2b
1 of 15
No
No
Drer\egr4
1 of 15
No
No
Drer\klf11a
1 of 15
No
No
Drer\klf15
1 of 15
No
No
Drer\si:ch211-117k10.3
1 of 15
No
No
Drer\sp2
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (5)
Cele\odd-2
7 of 15
Yes
Yes
Cele\odd-1
5 of 15
No
Yes
Cele\egrh-1
1 of 15
No
No
Cele\egrh-3
1 of 15
No
No
Cele\K11D2.4
1 of 15
No
No
Arabidopsis thaliana (thale-cress) (11)
Atha\AT1G14580
1 of 9
Yes
No
Atha\AT3G45260
1 of 9
Yes
Yes
Atha\AT5G60470
1 of 9
Yes
Yes
Atha\IDD1
1 of 9
Yes
Yes
Atha\IDD2
1 of 9
Yes
No
Atha\IDD4
1 of 9
Yes
No
Atha\IDD5
1 of 9
Yes
Yes
Atha\IDD7
1 of 9
Yes
Yes
Atha\JKD
1 of 9
Yes
Yes
Atha\MGP
1 of 9
Yes
Yes
Atha\NUC
1 of 9
Yes
Yes
Saccharomyces cerevisiae (Brewer's yeast) (6)
Scer\CMR3
1 of 15
Yes
Yes
Scer\CRZ1
1 of 15
Yes
No
Scer\FZF1
1 of 15
Yes
No
Scer\MSN2
1 of 15
Yes
No
Scer\MSN4
1 of 15
Yes
No
Scer\YPR015C
1 of 15
Yes
Yes
Schizosaccharomyces pombe (Fission yeast) (2)
Spom\hsr1
2 of 12
Yes
Yes
Spom\prz1
1 of 12
No
No
Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG09190CW8 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila melanogaster
fruit fly
Dmel\odd
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00000900
Drosophila simulans
Dsim\GD22743
Drosophila sechellia
Dsec\GM18135
Drosophila erecta
Dere\GG24424
Drosophila yakuba
Dyak\GE14830
Drosophila ananassae
Dana\GF14661
Drosophila pseudoobscura pseudoobscura
Dpse\GA17731
Drosophila persimilis
Dper\GL19469
Drosophila willistoni
Dwil\GK15475
Drosophila virilis
Dvir\GJ17592
Drosophila mojavensis
Dmoj\GI17766
Drosophila grimshawi
Dgri\GH13191
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG09150A64 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17008637
Musca domestica
House fly
Mdoa\17004429
Musca domestica
House fly
Mdoa\17007418
Musca domestica
House fly
Mdoa\17004494
Musca domestica
House fly
Mdoa\17004479
Glossina morsitans
Tsetse fly
Gmor\GMOY002985
Glossina morsitans
Tsetse fly
Gmor\GMOY008647
Glossina morsitans
Tsetse fly
Gmor\GMOY003430
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_07567
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_07563
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_07571
Mayetiola destructor
Hessian fly
Mdes\Mdes011853
Mayetiola destructor
Hessian fly
Mdes\Mdes011854
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL008961
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL007453
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL007450
Anopheles darlingi
American malaria mosquito
Adar\ADAC003639
Anopheles darlingi
American malaria mosquito
Adar\ADAC010373
Anopheles darlingi
American malaria mosquito
Adar\ADAC005347
Anopheles gambiae
Malaria mosquito
Agam\ODDA
Anopheles gambiae
Malaria mosquito
Agam\ODDB
Anopheles gambiae
Malaria mosquito
Agam\ODR2
Anopheles gambiae
Malaria mosquito
Agam\ODR1
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ017141
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ010652
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ010649
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0ES3 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA008844
Bombyx mori
Silkmoth
Bmor\BGIBMGA008808
Bombyx mori
Silkmoth
Bmor\BGIBMGA008843
Bombyx mori
Silkmoth
Bmor\BGIBMGA009541
Danaus plexippus
Monarch butterfly
Dple\DPOGS208437-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS208434-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS208435-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL007222
Heliconius melpomene
Postman butterfly
Hmel\HMEL007225
Apis florea
Little honeybee
Aflo\5320484548
Apis florea
Little honeybee
Aflo\2798738868
Apis florea
Little honeybee
Aflo\5320484580
Apis mellifera
Western honey bee
Amel\GB49914
Apis mellifera
Western honey bee
Amel\GB49912
Apis mellifera
Western honey bee
Amel\LOC410399
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP24836
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP24835
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP24850
Bombus terrestris
Buff-tailed bumblebee
Bter\15210019
Bombus terrestris
Buff-tailed bumblebee
Bter\15210016
Bombus terrestris
Buff-tailed bumblebee
Bter\15210017
Linepithema humile
Argentine ant
Lhum\LH25953
Linepithema humile
Argentine ant
Lhum\LH21635
Linepithema humile
Argentine ant
Lhum\LH11635
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:0012a4
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:00185b
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:001858
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG004848
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG004838
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG004840
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_05716
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_05719
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_05715
Tribolium castaneum
Red flour beetle
Tcas\bowl
Tribolium castaneum
Red flour beetle
Tcas\sob
Tribolium castaneum
Red flour beetle
Tcas\odd
Pediculus humanus
Human body louse
Phum\PHUM125080
Pediculus humanus
Human body louse
Phum\PHUM445550
Pediculus humanus
Human body louse
Phum\PHUM125070
Rhodnius prolixus
Kissing bug
Rpro\RPRC011444
Rhodnius prolixus
Kissing bug
Rpro\RPRC011812
Rhodnius prolixus
Kissing bug
Rpro\RPRC010843
Cimex lectularius
Bed bug
Clec\CLEC007980
Cimex lectularius
Bed bug
Clec\CLEC007981
Cimex lectularius
Bed bug
Clec\CLEC007979
Cimex lectularius
Bed bug
Clec\CLEC006352
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI008391
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI007518
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_13786
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_13779
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_13787
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X088Q )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR002904
Strigamia maritima
European centipede
Smar\SMAR005255
Ixodes scapularis
Black-legged tick
Isca\ISCW017921
Ixodes scapularis
Black-legged tick
Isca\ISCW005884
Stegodyphus mimosarum
African social velvet spider
Smim\KFM61451.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM78088.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM75794.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur09g03230
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_238529
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_347540
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_119144
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_250798
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0LRE )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Osr
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000006616
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000021903
Gallus gallus
Domestic chicken
Ggal\OSR2
Gallus gallus
Domestic chicken
Ggal\OSR1
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v7.1)
Drosophila melanogaster (Fruit fly) (27)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
bowl
4 of 10
sob
3 of 10
drm
2 of 10
Aef1
1 of 10
btd
1 of 10
cbt
1 of 10
Cf2
1 of 10
CG7368
1 of 10
CG10959
1 of 10
CG12071
1 of 10
CG12236
1 of 10
CG14655
1 of 10
CG16779
1 of 10
CG32767
1 of 10
CG32772
1 of 10
Clamp
1 of 10
dar1
1 of 10
hkb
1 of 10
Klf15
1 of 10
Kr
1 of 10
l(3)neo38
1 of 10
luna
1 of 10
pad
1 of 10
sna
1 of 10
Sp1
1 of 10
sr
1 of 10
sug
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    OSR1; odd-skipped related transcription factor 1
    5 of 15
    608891
        OSR2; odd-skipped related transciption factor 2
        4 of 15
        611297
            Functional Complementation Data
            Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
            Interactions
            Summary of Physical Interactions
            Summary of Genetic Interactions
            esyN Network Diagram
            Starting gene(s)
            Interaction type
            Interacting gene(s)
            Reference
            Starting gene(s)
            Interaction type
            Interacting gene(s)
            Reference
            External Data
            Linkouts
            BioGRID - A database of protein and genetic interactions.
            DroID - A comprehensive database of gene and protein interactions.
            InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
            MIST (protein-protein) - An integrated Molecular Interaction Database
            Pathways
            Signaling Pathways (FlyBase)
            Metabolic Pathways
            External Data
            Linkouts
            Genomic Location and Detailed Mapping Data
            Chromosome (arm)
            2L
            Recombination map
            2-10
            Cytogenetic map
            24A1-24A1
            Sequence location
            2L:3,604,224..3,606,756 [-]
            FlyBase Computed Cytological Location
            Cytogenetic map
            Evidence for location
            24A1-24A1
            Limits computationally determined from genome sequence between P{EP}ThorEP818&P{lacW}Thork07736 and P{PZ}oddrF111&P{PZ}for06860
            Experimentally Determined Cytological Location
            Cytogenetic map
            Notes
            References
            24A1-24A2
            (determined by in situ hybridisation)
            (Spradling et al., 1999)
            24A-24A
            (determined by in situ hybridisation)
            (Hart et al., 1996)
            24A1-24A2
            (BDGP Project Members, 1994-1999)
            24A1-24A3
            (determined by in situ hybridisation)
            (Coulter et al., 1990)
            Experimentally Determined Recombination Data
            Location
            2-10
            (FlyBase, 2016)
            2-8.9
            (Comeron et al., 2012)
            2-8
            (Tearle and Nusslein-Volhard, 1987)
            Left of (cM)
            Right of (cM)
            Notes
            Stocks and Reagents
            Stocks (23)
            Genomic Clones (24)
            cDNA Clones (132)
             

            Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

            cDNA clones, fully sequences
            BDGP DGC clones
            Other clones
              Drosophila Genomics Resource Center cDNA clones

              For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

              cDNA Clones, End Sequenced (ESTs)
              BDGP DGC clones
              Other clones
              RNAi and Array Information
              Linkouts
              DRSC - Results frm RNAi screens
              GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
              Antibody Information
              Laboratory Generated Antibodies
               
              polyclonal
              (Perrin et al., 2004)
              Commercially Available Antibodies
               
              Other Information
              Relationship to Other Genes
              Source for database identify of
              Source for database merge of
              Additional comments
              Other Comments
              Class IV neuron formation is promoted by slp1.
              (Karim and Moore, 2011)
              RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
              (Boutros et al., 2004)
              Ectopic expression of odd can induce invaginations in the leg disc epithelium and morphological changes in the adult leg that are characteristic of endogenous invaginating joint cells.
              (Hao et al., 2003)
              odd, sob and bowl encode closely related zinc finger proteins. sob has additional similarities to odd that suggests parallels with other segmentation gene homologues. odd and sob may be regulated in common and share some overlapping functions during development. In contrast, the distinct expression of bowl, less tightly linked to odd, and analysis of bowl mutations (FBrf0089187) indicates a more divergent developmental role.
              (Hart et al., 1996)
              Molecular and genetic analysis of bowl reveals the functions of bowl during embryogenesis are distinct from odd despite the structural similarities between the two genes.
              (Wang and Coulter, 1996)
              odd and nkd are required to restrict en expression. odd represses expression of ftz, an activator of en. nkd prevents activation of en by ftz without affecting ftz expression. wg expression is regulated by odd and prd. odd represses wg expression, prd restricts the domain of expression of odd. In odd mutants the altered expression patterns of ftz, en and wg lead to the changes in positional identities of cells that causes mirror image duplications of the body pattern.
              (Mullen and DiNardo, 1995)
              Ectopic ttk expression causes complete or near complete repression of ftz and significant repression of eve, odd, h and runt.
              (Brown and Wu, 1993)
              The role of odd in the regulation of run mRNA expression in the early embryo has been investigated.
              (Klingler and Gergen, 1993)
              Expression of odd is repressed by ectopic eve expression.
              (Manoukian and Krause, 1992)
              Mutant analysis shows that wild type odd function is required to set up expression of ac and sc in row D of the embryonic proneural cluster.
              (Skeath et al., 1992)
              Mutations in zygotic pair rule gene odd do not interact with RpII140wimp.
              (Parkhurst and Ish-Horowicz, 1991)
              The transition of prd RNA expression from the early 'pair-rule' pattern to the 'segment-polarity' pattern is regulated by the secondary pair-rule genes opa and odd.
              (Baumgartner and Noll, 1990)
              Isolated from an oddhd1 genomic library using a P-element homologous fragment.
              (Coulter et al., 1990)
              odd has been cloned and sequenced.
              (Coulter et al., 1990)
              Genetic analysis demonstrates that odd is dispensable for efficient homeotic gene expression in the visceral mesoderm.
              (Tremml and Bienz, 1989)
              Origin and Etymology
              Discoverer
              Etymology
              Identification
              External Crossreferences and Linkouts ( 37 )
              Sequence Crossreferences
              NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
              GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
              GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
              RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
              UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
              Other crossreferences
              BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
              Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
              Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
              Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
              Flygut - An atlas of the Drosophila adult midgut
              GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
              iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
              InterPro - A database of protein families, domains and functional sites
              KEGG Genes - Molecular building blocks of life in the genomic space.
              modMine - A data warehouse for the modENCODE project
              SignaLink - A signaling pathway resource with multi-layered regulatory networks.
              Linkouts
              BioGRID - A database of protein and genetic interactions.
              DroID - A comprehensive database of gene and protein interactions.
              DRSC - Results frm RNAi screens
              FLIGHT - Cell culture data for RNAi and other high-throughput technologies
              FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
              FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
              FlyMine - An integrated database for Drosophila genomics
              Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
              InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
              MIST (protein-protein) - An integrated Molecular Interaction Database
              Synonyms and Secondary IDs (15)
              Reported As
              Symbol Synonym
              CG3851
              (Ibrahim et al., 2013, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Lu et al., 2009, Perkins et al., 2009, Gonzalez-Aguero et al., 2005, Kreiman, 2004)
              ODD
              (Blatti et al., 2015, Kim et al., 2010, Lüer and Technau, 2009, Udolph et al., 2009, Sonnenfeld et al., 2005, Sedaghat et al., 2002)
              Odd
              (Laddada et al., 2019, Drechsler et al., 2018, Ruiz-Losada et al., 2018, Schwarz et al., 2018, Yu et al., 2018, Cannon et al., 2017, Werner et al., 2017, Gao et al., 2016, Gao et al., 2014, Honti et al., 2014, Ocorr et al., 2014, Castellanos et al., 2013, Hombría and Sotillos, 2013, Johnson et al., 2011, Kulkarni et al., 2011, Singh et al., 2011, Zhang et al., 2011, Mace et al., 2010, Monastirioti et al., 2010, Reim and Frasch, 2010, Babaoglan et al., 2009, Mann et al., 2009, Das et al., 2008, Dougherty et al., 2008, Frandsen et al., 2008, Homem and Peifer, 2008, Miguel-Aliaga et al., 2008, Mulinari et al., 2008, Noyes et al., 2008, Mandal et al., 2007, Mann et al., 2007, Monier et al., 2007, Tao et al., 2007, Zhao et al., 2007, Albrecht et al., 2006, Han et al., 2006, Muratoglu et al., 2006, Yi, 2006, Zaffran et al., 2006, Pedra et al., 2004, Perrin et al., 2004, Popichenko and Paululat, 2004, Rath et al., 2002)
              l(2)01863
              (Meister and Braun, 1995.10, BDGP Project Members, 1994-1999)
              odd
              (Banerjee et al., 2019, Clark et al., 2019, Graham et al., 2019, Kwasnieski et al., 2019, Lopez-Gonzalez et al., 2019, Shokri et al., 2019, Bischof et al., 2018, Transgenic RNAi Project members, 2017-, Sarov et al., 2016, Urbach et al., 2016, Duque and Sinha, 2015, Kok et al., 2015, Nadimpalli et al., 2015, Schertel et al., 2015, Ciglar et al., 2014, Muliyil and Narasimha, 2014, Chen et al., 2013, Combs and Eisen, 2013, Ducuing et al., 2013, Jin et al., 2013, Mirzoyan and Pandur, 2013, Samee and Sinha, 2013, Saunders et al., 2013, Webber et al., 2013, Del Signore et al., 2012, Kim et al., 2012, Yuan et al., 2012, Zhou et al., 2012, Ahn et al., 2011, Albrecht et al., 2011, Fowlkes et al., 2011, Gao et al., 2011, Grigorian et al., 2011, Kaplan et al., 2011, Karim and Moore, 2011, Kuzin et al., 2011, Marcu et al., 2011, Schroeder et al., 2011, Tripura et al., 2011, Turchyn et al., 2011, Biehs et al., 2010, Braid et al., 2010, Kong et al., 2010, Kong et al., 2010, Yassin et al., 2010, Greenberg and Hatini, 2009, Iovino et al., 2009, Kantorovitz et al., 2009, Lee et al., 2009, Liu et al., 2009, Lu et al., 2009, Mulinari and Häcker, 2009, Papatsenko et al., 2009, Pisarev et al., 2009, Schaaf et al., 2009, Sellin et al., 2009, Tchuraev and Galimzyanov, 2009, Brás-Pereira and Casares, 2008, Nusinow et al., 2008, Schroeder and Gaul, 2008, Segal et al., 2008, Surkova et al., 2008, Surkova et al., 2008, Vincent et al., 2008, Wheeler et al., 2008, Bras-Pereira and Casares, 2007, Christensen and Cook, 2007.5.8, Ciechanska et al., 2007, Cook, 2007.1.23, Johnson et al., 2007, Lecuyer et al., 2007, Lo et al., 2007, Sandmann et al., 2007, Sprecher et al., 2007, Tena et al., 2007, Tomancak et al., 2007, Bossing and Brand, 2006, Bras-Pereira et al., 2006, Layden et al., 2006, Sellin et al., 2006, Wheeler et al., 2006, Copley, 2005, Goldstein et al., 2005, Peel et al., 2005, Berman et al., 2004, Grad et al., 2004, Kreiman, 2004, Chang et al., 2000)
              ods
              (Smoller et al., 1991)
              Name Synonyms
              ODD-SKIPPED
              (Shafer and Taghert, 2009)
              Odd Skipped
              (Homem and Peifer, 2008)
              Odd skipped
              (Ahmad, 2017, Karim and Moore, 2011, Kuzina et al., 2011, Kim et al., 2010, Babaoglan et al., 2009)
              Odd-Skipped
              (Singh et al., 2011)
              Odd-skipped
              (Laddada et al., 2019, Baldeosingh et al., 2018, Yu et al., 2018, Gao et al., 2014, Mannervik, 2014, Ocorr et al., 2014, Castellanos et al., 2013, Hombría and Sotillos, 2013, Johnson et al., 2011, Zhang et al., 2011, Lüer and Technau, 2009, Udolph et al., 2009, Das et al., 2008, Frandsen et al., 2008, Miguel-Aliaga et al., 2008, Mulinari et al., 2008, Monier et al., 2007, Newfeld and Johnson, 2007, Tao et al., 2007, Albrecht et al., 2006, Muratoglu et al., 2006, Murray et al., 2006, Kaplan et al., 2005, Kuzin et al., 2005, Cheesman et al., 2004)
              odd paired
              (Vincent et al., 2008)
              odd skipped
              (Urbach et al., 2016, Ibrahim et al., 2013, Biehs et al., 2010, Lu et al., 2009, Mulinari and Häcker, 2009, Chanana et al., 2007, Bossing and Brand, 2006)
              odd-skipped
              (Wieschaus and Nüsslein-Volhard, 2016, Webber et al., 2013, Ahn et al., 2011, Kuzin et al., 2011, Marcu et al., 2011, Schroeder et al., 2011, Braid et al., 2010, Greenberg and Hatini, 2009, Iovino et al., 2009, Lee et al., 2009, Pisarev et al., 2009, Zamparo and Perkins, 2009, Ishihara and Shibata, 2008, Surkova et al., 2008, Larsen et al., 2006, Larsen et al., 2006, Goldstein et al., 2005, Berman et al., 2004)
              oddskipped
              (Wheeler et al., 2006)
              Secondary FlyBase IDs
              • FBgn0010502
              Datasets (0)
              Study focus (0)
              Experimental Role
              Project
              Project Type
              Title
              References (368)