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General Information
Symbol
Dmel\odd
Species
D. melanogaster
Name
odd skipped
Annotation Symbol
CG3851
Feature Type
FlyBase ID
FBgn0002985
Gene Model Status
Stock Availability
Gene Snapshot
In progress.Contributions welcome.
Also Known As
l(2)01863
Key Links
Genomic Location
Cytogenetic map
Sequence location
2L:3,604,224..3,606,756 [-]
Recombination map
2-10
Sequence
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
Function
GO Summary Ribbons
Protein Family (UniProt)
Belongs to the Odd C2H2-type zinc-finger protein family. (P23803)
Summaries
Gene Group (FlyBase)
C2H2 ZINC FINGER TRANSCRIPTION FACTORS -
Zinc finger C2H2 transcription factors are sequence-specific DNA binding proteins that regulate transcription. They possess DNA-binding domains that are formed from repeated Cys2His2 zinc finger motifs. (Adapted from PMID:1835093, FBrf0220103 and FBrf0155739).
Protein Function (UniProtKB)
Pair-rule protein that determines both the size and polarity of even-numbered as well as odd-numbered parasegments during embryogenesis. DNA-binding transcription factor that acts primarily as a transcriptional repressor but can also function as a transcriptional activator, depending on the stage of development and spatial restrictions. May function redundantly with odd and drm in leg joint formation during the larval stages, acting downstream of Notch activation.
(UniProt, P23803)
Phenotypic Description (Red Book; Lindsley and Zimm 1992)
odd: odd skipped
Embryonic lethal; posterior part of the denticle band and adjacent naked cuticle replaced by mirror-image duplication of the anterior part of the denticle band and adjacent naked cuticle in T2, A1, A3, A5, and A7. Pole-cell-transplantation experiments indicate that odd+ not maternally required. Positional expression of ftz unaffected (Carrol and Scott, 1986, Cell 54: 113-26). However, stripes of en expression are broader than normal in even-numbered, but of normal width in odd-numbered parasegments; Ubx expression is consequently low in broader-than-normal stripes in even-numbered parasegments (Martinez-Arias and White, 1988, Development 102: 325-38).
Summary (Interactive Fly)
transcription factor - zinc finger - pair rule gene - mutants associated with cuticle defects that are limited to alternate--odd-numbered--segments - labels a group of distinct neurons associated with the mushroom body and optic lobe in the adult brain
Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the GBrowse view of Dmel\odd or the JBrowse view of Dmel\odd for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model
Gene model reviewed during 5.49
Sequence Ontology: Class of Gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
FBtr0077557
2347
392
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
FBpp0077246
44.6
392
8.66
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)
392 (aa); 45 (kD predicted)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\odd using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Gene Ontology (16 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
non-traceable author statement
(assigned by UniProt )
inferred from sequence or structural similarity
inferred from biological aspect of ancestor with PANTHER:PTN000367524
(assigned by GO_Central )
Biological Process (12 terms)
Terms Based on Experimental Evidence (9 terms)
CV Term
Evidence
References
inferred from mutant phenotype
(assigned by UniProt )
inferred from mutant phenotype
(assigned by UniProt )
inferred from mutant phenotype
(assigned by UniProt )
inferred from direct assay
inferred from direct assay
(assigned by UniProt )
inferred from mutant phenotype
(assigned by CACAO )
inferred from mutant phenotype
(assigned by UniProt )
Terms Based on Predictions or Assertions (6 terms)
CV Term
Evidence
References
inferred from biological aspect of ancestor with PANTHER:PTN002306374
(assigned by GO_Central )
inferred from biological aspect of ancestor with PANTHER:PTN002306374
(assigned by GO_Central )
inferred from biological aspect of ancestor with PANTHER:PTN002306374
(assigned by GO_Central )
inferred from biological aspect of ancestor with PANTHER:PTN000367524
(assigned by GO_Central )
inferred from biological aspect of ancestor with PANTHER:PTN000367524
(assigned by GO_Central )
inferred from sequence or structural similarity
Cellular Component (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
inferred from sequence or structural similarity
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
dorsal ectoderm anlage

Comment: anlage in statu nascendi

mesectoderm anlage

Comment: anlage in statu nascendi

mesoderm anlage

Comment: anlage in statu nascendi

ventral ectoderm anlage

Comment: anlage in statu nascendi

antennal anlage in statu nascendi

Comment: reported as procephalic ectoderm anlage in statu nascendi

dorsal head epidermis anlage in statu nascendi

Comment: reported as procephalic ectoderm anlage in statu nascendi

visual anlage in statu nascendi

Comment: reported as procephalic ectoderm anlage in statu nascendi

antennal primordium

Comment: reported as procephalic ectoderm primordium

central brain primordium

Comment: reported as procephalic ectoderm primordium

visual primordium

Comment: reported as procephalic ectoderm primordium

dorsal head epidermis primordium

Comment: reported as procephalic ectoderm primordium

lateral head epidermis primordium

Comment: reported as procephalic ectoderm primordium

ventral head epidermis primordium

Comment: reported as procephalic ectoderm primordium

radioisotope in situ
Stage
Tissue/Position (including subcellular localization)
Reference
RT-PCR
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
Expression was examined at four phases of embryonic stage 5. The striped pattern becomes visible in phase 1 (0-5'), all stripes except stripe 7 are expressed during phase 2 (5-17'), and their spacing and expression levels become largely uniform by phase 3 (17-30'). The stripes initially appear less clearly separated and more graded.
In stage 11 embryos, odd is expressed in stripes that are adjacent and posterior to hh-expressing cells in each parasegment. It is also expressed in the presumptive foregut.
Expression assayed at stages 9, 11, 13, and 17. Expression may be continuous between assayed stages in some tissues.
The odd, sob and drm transcripts are detected an identical pattern in the third instar leg disc. There is segmental expression manifested as concentric rings on the distal edges of each presumptive leg segment not including the 4 tarsal segments (i.e. 5 rings of expression). There is an additional area of expression in the center of the disc that may correspond to a track of glial cells. The expression of drm is observed to begin during early larval development as a proximal ring of expression corresponding to the coxa. As larval development proceeds additional rings of expression are observed until the full complement of five rings is observed. Expression of odd, sob and drm occur in cells that are adjacent and distal to cells expressing the N ligands, Dl and Ser.
At the cellular blastoderm stage, odd transcripts accumulate in 7 transverse stripes that are 3-4 cells wide and correspond to the odd-numbered segments. A domain of expression is also observed at 85-100% egg length. At around the time of gastrulation, the stripe pattern changes to a segment polarity pattern of 14 stripes. The odd stripes are strongest in the blastoderm stage and diminish intensity when they are expressed in the segment polarity pattern. The odd expression pattern overlaps that of sob at these stages. In later stages, odd continues to be expressed in the epidermis but is also expressed in the proventriculus, proximal Malpighian tubules, brain, pharyngeal muscles, ventral nerve cord, pericardial cells, and garland cells.
odd transcription is repressed by ectopic eve protein in evehs.PS embryos. Timing suggests that eve is a direct regulator of odd.
odd transcripts are first detected in the syncytial blastoderm in a 5 cell wide stripe at 62% egg length. During cellularization, the pattern evolves into one of six regular stripes of ~3-4 cell widths. There is a noticeable posterior and dorsal lag in the generation of these stripes. A non-periodic anterior domain of expression is also observed which persists through subsequent stages. Labelling with ftz indicates that the resolution of the odd pattern into six stripes is coincident with the appearance of the seven stripe ftz pattern. A 7th posteriormost odd stripe appears at 15% egg length after nuclear elongation but before the completion of cellularization. During gastrulation, this pattern evolves into a pattern in which odd is expressed in homologous portions of each segment. This occurs through the narrowing of the original seven stripes and the appearance of 8 new stripes. Results of labelling with en suggest that each of the seven odd stripes lies posterior to an even-numbered en stripe.
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
Around 90% of odd positive adult neurons are positive for Scer\GAL4ChAT.7.4.
In early third instar larvae, the highest levels of odd are observed in medullary zone prohemocytes in the lymph gland. At this time odd is downregulated in terminally differentiated plasmatocytes. This epression pattern is maintained until the late-third larval instar. odd is expressed in prohemocytes throughout lymph gland development and maturation and is downregulated as pro-hemocytes differentiate.
odd protein is expressed in the embryonic lymph gland.
Expression is observed in A6 to A9 dMP2 neurons.
odd protein is expressed in the developing embryonic brain from embryonic stage 11, and is expressed in three discrete clusters at the end of embryogenesis. It is also expressed in a few neuroblasts and neurons per segment in the ventral nerve cord. odd protein is transiently expressed in a small subset of midline glial cells at embryonic stage 9. At embryonic stage 16, odd protein is expressed in a ring of cells encircling the salivary gland duct about midway along its length. This ring is derived from six odd-positive cells in the ventral epidermis of parasegment 2 at embryonic stage 11; these cells reorganize to form a cluster by stage 12, then migrate anteriorly and dorsally to their final position.
odd protein is expressed in two rows of mesodermal cells flanking the dorsal midline of late stage embryos. These cells are physically close to, and flank, the cardioblasts. Pericardial cells expressing odd protein do not express either eve or tin, which are expressed in all previously identified pericardial cells; they do however also express zfh1. odd-expressing pericardial cells lie lateral to tin-expressing pericardial cells
Marker for
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
Reporter: P{GAL4}oddMC
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{lacZ}oddrK111
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{PT1}odd106
Stage
Tissue/Position (including subcellular localization)
Reference
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\odd in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 1-3
  • Stages(s) 4-6
  • Stages(s) 7-8
  • Stages(s) 9-10
  • Stages(s) 11-12
  • Stages(s) 13-16
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 25 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 12 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of odd
Transgenic constructs containing regulatory region of odd
Deletions and Duplications ( 12 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
Other Phenotypes
Allele
Phenotype manifest in
Allele
abdominal segment 1 & embryonic epidermis
abdominal segment 3 & embryonic epidermis
abdominal segment 5 & embryonic epidermis
abdominal segment 7 & embryonic epidermis
leg & adult cuticle, with Scer\GAL4ptc-559.1
leg & adult cuticle | somatic clone, with Scer\GAL4Act5C.PI
mesothoracic segment & embryonic epidermis
Orthologs
Human Orthologs (via DIOPT v7.1)
Homo sapiens (Human) (9)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
5 of 15
Yes
No
4 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
Model Organism Orthologs (via DIOPT v7.1)
Mus musculus (laboratory mouse) (8)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
Mmus\Osr1
5 of 15
Yes
No
3 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
Rattus norvegicus (Norway rat) (2)
4 of 13
Yes
No
4 of 13
Yes
No
Xenopus tropicalis (Western clawed frog) (8)
3 of 12
Yes
No
3 of 12
Yes
No
1 of 12
No
No
1 of 12
No
No
1 of 12
No
No
1 of 12
No
No
1 of 12
No
No
1 of 12
No
Yes
Danio rerio (Zebrafish) (9)
5 of 15
Yes
No
4 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (5)
7 of 15
Yes
Yes
5 of 15
No
Yes
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
Arabidopsis thaliana (thale-cress) (11)
1 of 9
Yes
No
1 of 9
Yes
Yes
1 of 9
Yes
Yes
1 of 9
Yes
Yes
1 of 9
Yes
No
1 of 9
Yes
No
1 of 9
Yes
Yes
1 of 9
Yes
Yes
1 of 9
Yes
Yes
1 of 9
Yes
Yes
1 of 9
Yes
Yes
Saccharomyces cerevisiae (Brewer's yeast) (6)
1 of 15
Yes
Yes
1 of 15
Yes
No
1 of 15
Yes
No
1 of 15
Yes
No
1 of 15
Yes
No
1 of 15
Yes
Yes
Schizosaccharomyces pombe (Fission yeast) (2)
2 of 12
Yes
Yes
1 of 12
No
No
Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG09190CW8 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila melanogaster
fruit fly
Drosophila suzukii
Spotted wing Drosophila
Drosophila simulans
Drosophila sechellia
Drosophila erecta
Drosophila yakuba
Drosophila ananassae
Drosophila pseudoobscura pseudoobscura
Drosophila persimilis
Drosophila willistoni
Drosophila virilis
Drosophila mojavensis
Drosophila grimshawi
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG09150A64 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Musca domestica
House fly
Musca domestica
House fly
Musca domestica
House fly
Musca domestica
House fly
Glossina morsitans
Tsetse fly
Glossina morsitans
Tsetse fly
Glossina morsitans
Tsetse fly
Lucilia cuprina
Australian sheep blowfly
Lucilia cuprina
Australian sheep blowfly
Lucilia cuprina
Australian sheep blowfly
Mayetiola destructor
Hessian fly
Mayetiola destructor
Hessian fly
Aedes aegypti
Yellow fever mosquito
Aedes aegypti
Yellow fever mosquito
Aedes aegypti
Yellow fever mosquito
Anopheles darlingi
American malaria mosquito
Anopheles darlingi
American malaria mosquito
Anopheles darlingi
American malaria mosquito
Anopheles gambiae
Malaria mosquito
Anopheles gambiae
Malaria mosquito
Anopheles gambiae
Malaria mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Culex quinquefasciatus
Southern house mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0ES3 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bombyx mori
Silkmoth
Bombyx mori
Silkmoth
Bombyx mori
Silkmoth
Danaus plexippus
Monarch butterfly
Danaus plexippus
Monarch butterfly
Danaus plexippus
Monarch butterfly
Heliconius melpomene
Postman butterfly
Heliconius melpomene
Postman butterfly
Apis florea
Little honeybee
Apis florea
Little honeybee
Apis florea
Little honeybee
Apis mellifera
Western honey bee
Apis mellifera
Western honey bee
Apis mellifera
Western honey bee
Bombus impatiens
Common eastern bumble bee
Bombus impatiens
Common eastern bumble bee
Bombus impatiens
Common eastern bumble bee
Bombus terrestris
Buff-tailed bumblebee
Bombus terrestris
Buff-tailed bumblebee
Bombus terrestris
Buff-tailed bumblebee
Linepithema humile
Argentine ant
Linepithema humile
Argentine ant
Linepithema humile
Argentine ant
Megachile rotundata
Alfalfa leafcutting bee
Megachile rotundata
Alfalfa leafcutting bee
Megachile rotundata
Alfalfa leafcutting bee
Nasonia vitripennis
Parasitic wasp
Nasonia vitripennis
Parasitic wasp
Nasonia vitripennis
Parasitic wasp
Dendroctonus ponderosae
Mountain pine beetle
Dendroctonus ponderosae
Mountain pine beetle
Dendroctonus ponderosae
Mountain pine beetle
Tribolium castaneum
Red flour beetle
Tribolium castaneum
Red flour beetle
Tribolium castaneum
Red flour beetle
Pediculus humanus
Human body louse
Pediculus humanus
Human body louse
Pediculus humanus
Human body louse
Rhodnius prolixus
Kissing bug
Rhodnius prolixus
Kissing bug
Rhodnius prolixus
Kissing bug
Cimex lectularius
Bed bug
Cimex lectularius
Bed bug
Cimex lectularius
Bed bug
Cimex lectularius
Bed bug
Acyrthosiphon pisum
Pea aphid
Acyrthosiphon pisum
Pea aphid
Zootermopsis nevadensis
Nevada dampwood termite
Zootermopsis nevadensis
Nevada dampwood termite
Zootermopsis nevadensis
Nevada dampwood termite
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X088Q )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Strigamia maritima
European centipede
Ixodes scapularis
Black-legged tick
Ixodes scapularis
Black-legged tick
Stegodyphus mimosarum
African social velvet spider
Stegodyphus mimosarum
African social velvet spider
Stegodyphus mimosarum
African social velvet spider
Tetranychus urticae
Two-spotted spider mite
Daphnia pulex
Water flea
Daphnia pulex
Water flea
Daphnia pulex
Water flea
Daphnia pulex
Water flea
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0LRE )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Ciona intestinalis
Vase tunicate
Ciona intestinalis
Vase tunicate
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Paralogs
Paralogs (via DIOPT v7.1)
Drosophila melanogaster (Fruit fly) (27)
4 of 10
3 of 10
2 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    Summary of Genetic Interactions
    esyN Network Diagram
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    External Data
    Linkouts
    BioGRID - A database of protein and genetic interactions.
    DroID - A comprehensive database of gene and protein interactions.
    InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Pathways
    Gene Group - Pathway Membership (FlyBase)
    External Data
    Linkouts
    SignaLink - A signaling pathway resource with multi-layered regulatory networks.
    Genomic Location and Detailed Mapping Data
    Chromosome (arm)
    2L
    Recombination map
    2-10
    Cytogenetic map
    Sequence location
    2L:3,604,224..3,606,756 [-]
    FlyBase Computed Cytological Location
    Cytogenetic map
    Evidence for location
    24A1-24A1
    Limits computationally determined from genome sequence between P{EP}ThorEP818&P{lacW}Thork07736 and P{PZ}oddrF111&P{PZ}for06860
    Experimentally Determined Cytological Location
    Cytogenetic map
    Notes
    References
    24A1-24A2
    (determined by in situ hybridisation)
    24A-24A
    (determined by in situ hybridisation)
    24A1-24A3
    (determined by in situ hybridisation)
    Experimentally Determined Recombination Data
    Left of (cM)
    Right of (cM)
    Notes
    Stocks and Reagents
    Stocks (22)
    Genomic Clones (24)
    cDNA Clones (132)
     

    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

    cDNA clones, fully sequences
    BDGP DGC clones
    Other clones
      Drosophila Genomics Resource Center cDNA clones

      For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

      cDNA Clones, End Sequenced (ESTs)
      BDGP DGC clones
      Other clones
      RNAi and Array Information
      Linkouts
      DRSC - Results frm RNAi screens
      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
      Antibody Information
      Laboratory Generated Antibodies
       
      Commercially Available Antibodies
       
      Other Information
      Relationship to Other Genes
      Source for database identify of
      Source for database merge of
      Additional comments
      Other Comments
      Class IV neuron formation is promoted by slp1.
      RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
      Ectopic expression of odd can induce invaginations in the leg disc epithelium and morphological changes in the adult leg that are characteristic of endogenous invaginating joint cells.
      odd, sob and bowl encode closely related zinc finger proteins. sob has additional similarities to odd that suggests parallels with other segmentation gene homologues. odd and sob may be regulated in common and share some overlapping functions during development. In contrast, the distinct expression of bowl, less tightly linked to odd, and analysis of bowl mutations (FBrf0089187) indicates a more divergent developmental role.
      Molecular and genetic analysis of bowl reveals the functions of bowl during embryogenesis are distinct from odd despite the structural similarities between the two genes.
      odd and nkd are required to restrict en expression. odd represses expression of ftz, an activator of en. nkd prevents activation of en by ftz without affecting ftz expression. wg expression is regulated by odd and prd. odd represses wg expression, prd restricts the domain of expression of odd. In odd mutants the altered expression patterns of ftz, en and wg lead to the changes in positional identities of cells that causes mirror image duplications of the body pattern.
      Ectopic ttk expression causes complete or near complete repression of ftz and significant repression of eve, odd, h and runt.
      The role of odd in the regulation of run mRNA expression in the early embryo has been investigated.
      Expression of odd is repressed by ectopic eve expression.
      Mutant analysis shows that wild type odd function is required to set up expression of ac and sc in row D of the embryonic proneural cluster.
      Mutations in zygotic pair rule gene odd do not interact with RpII140wimp.
      The transition of prd RNA expression from the early 'pair-rule' pattern to the 'segment-polarity' pattern is regulated by the secondary pair-rule genes opa and odd.
      Isolated from an oddhd1 genomic library using a P-element homologous fragment.
      odd has been cloned and sequenced.
      Genetic analysis demonstrates that odd is dispensable for efficient homeotic gene expression in the visceral mesoderm.
      Origin and Etymology
      Discoverer
      Etymology
      Identification
      External Crossreferences and Linkouts ( 36 )
      Sequence Crossreferences
      NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
      RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
      UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
      Other crossreferences
      BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
      Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
      Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
      Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
      Flygut - An atlas of the Drosophila adult midgut
      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
      iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
      InterPro - A database of protein families, domains and functional sites
      KEGG Genes - Molecular building blocks of life in the genomic space.
      modMine - A data warehouse for the modENCODE project
      SignaLink - A signaling pathway resource with multi-layered regulatory networks.
      Linkouts
      BioGRID - A database of protein and genetic interactions.
      DroID - A comprehensive database of gene and protein interactions.
      DRSC - Results frm RNAi screens
      FLIGHT - Cell culture data for RNAi and other high-throughput technologies
      FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
      FlyMine - An integrated database for Drosophila genomics
      Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
      InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
      MIST (protein-protein) - An integrated Molecular Interaction Database
      Synonyms and Secondary IDs (15)
      Reported As
      Symbol Synonym
      odd
      (Graham et al., 2019, Lopez-Gonzalez et al., 2019, Shokri et al., 2019, Bischof et al., 2018, Transgenic RNAi Project members, 2017-, Sarov et al., 2016, Urbach et al., 2016, Duque and Sinha, 2015, Kok et al., 2015, Nadimpalli et al., 2015, Schertel et al., 2015, Ciglar et al., 2014, Muliyil and Narasimha, 2014, Chen et al., 2013, Combs and Eisen, 2013, Ducuing et al., 2013, Jin et al., 2013, Mirzoyan and Pandur, 2013, Samee and Sinha, 2013, Saunders et al., 2013, Webber et al., 2013, Del Signore et al., 2012, Kim et al., 2012, Yuan et al., 2012, Zhou et al., 2012, Ahn et al., 2011, Albrecht et al., 2011, Fowlkes et al., 2011, Gao et al., 2011, Grigorian et al., 2011, Kaplan et al., 2011, Karim and Moore, 2011, Kuzin et al., 2011, Marcu et al., 2011, Schroeder et al., 2011, Tripura et al., 2011, Turchyn et al., 2011, Biehs et al., 2010, Braid et al., 2010, Kong et al., 2010, Kong et al., 2010, Yassin et al., 2010, Greenberg and Hatini, 2009, Iovino et al., 2009, Kantorovitz et al., 2009, Lee et al., 2009, Liu et al., 2009, Lu et al., 2009, Mulinari and Häcker, 2009, Papatsenko et al., 2009, Pisarev et al., 2009, Schaaf et al., 2009, Sellin et al., 2009, Tchuraev and Galimzyanov, 2009, Brás-Pereira and Casares, 2008, Nusinow et al., 2008, Schroeder and Gaul, 2008, Segal et al., 2008, Surkova et al., 2008, Surkova et al., 2008, Vincent et al., 2008, Wheeler et al., 2008, Bras-Pereira and Casares, 2007, Christensen and Cook, 2007.5.8, Ciechanska et al., 2007, Cook, 2007.1.23, Johnson et al., 2007, Lecuyer et al., 2007, Lo et al., 2007, Sandmann et al., 2007, Sprecher et al., 2007, Tena et al., 2007, Tomancak et al., 2007, Bossing and Brand, 2006, Bras-Pereira et al., 2006, Layden et al., 2006, Sellin et al., 2006, Wheeler et al., 2006, Copley, 2005, Goldstein et al., 2005, Peel et al., 2005, Berman et al., 2004, Grad et al., 2004, Kreiman, 2004)
      Secondary FlyBase IDs
      • FBgn0010502
      Datasets (0)
      Study focus (0)
      Experimental Role
      Project
      Project Type
      Title
      References (363)