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Gene Dmel\okr

General Information
Symbol	Dmel\okr	Species	D. melanogaster
Name	okra	Annotation symbol	CG3736
Feature type	protein_coding_gene	FlyBase ID	FBgn0002989
Gene Model Status	Current	Stock availability	10 publicly available
Also Known As	rad54, DmRad54, okra
Genomic Location
Chromosome (arm)	2L	Recombination map	2-1
Cytogenetic map	23C4-23C4	Sequence location	2L:2,989,594..2,992,761 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene okra is referred to in FlyBase by the symbol Dmel\okr (CG3736, FBgn0002989). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ATP-dependent DNA helicase activity. There is experimental evidence that it is involved in the biological process: double-strand break repair via synthesis-dependent strand annealing; double-strand break repair; oogenesis; response to ionizing radiation; dorsal appendage formation. 18 alleles are reported. The phenotypes of these alleles are annotated with: chorion; egg; oocyte; presumptive oocyte; follicle cell; karyosome; micropyle; dorsal appendage; nucleus. It has one annotated transcript and one annotated polypeptide. Protein features are: DEAD-like helicase; Helicase, C-terminal; Rad54, N-terminal; SNF2-related. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1628198_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of okr. Gene sequence location is 2L:2989594..2992761.
External Summaries
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	okr: okra (T. Schupbach) Female sterile; homozygous females lay eggs which are of variable shapes; in the most extreme cases, the eggs are longer than normal, more pointed at the posterior end, and lack dorsal appendages, resembling eggs produced by the dominant female-sterile mutation Fs(2)D.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	References Chiolo et al., 2011, Cell 144(5): 732--744 Lake et al., 2011, PLoS Genet. 7(2): e1002005 Sequence features HFA00834 BKN27487
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 23C4-23C4   Limits computationally determined from genome sequence between P{PZ}lilli00632 and P{PZ}toc01361
Experimentally Determined Cytological Location
Cytogenetic map Notes References 23C1-23E6     (Pastink, 1996.12.20) 23C-23C     (Ghabrial, 1998.5.28) 23D-23E   (determined by in situ hybridisation)   (Kooistra et al., 1997) 23D-23D   (determined by in situ hybridisation)   (Eeken et al., 1997)
Experimentally Determined Recombination Data
Location	2-1   2-5.6 (Ghabrial et al., 1998) 2- (Pastink, 1996.12.20)
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\okr for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) okr-RA FBtr0077673  NM_057313   2880   784
Additional Transcript Data & Comments
Reported size (kB)	4.5, 2.7, 1.6 (northern blot) (Ghabrial et al., 1998) 3 (northern blot) (Kooistra et al., 1997)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein okr-PA   FBpp0077357   89.5   784   8.56     NP_476661   AAF51168
Additional Polypeptide Data & Comments
Reported size (kDa)	784 (aa) (Ghabrial et al., 1998, Kooistra et al., 1997)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • SNF2-related (IPR000330) Helicase, C-terminal (IPR001650) DEAD-like helicase (IPR014001) Rad54, N-terminal (IPR013967)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014134 AAF51168   AC010009   AC092187   AF069779 AAC24577   AF069780 AAC26857   AI260400   AI518818   AW943269   AY069599 AAL39744   CK131821   CO270774   CO283893   CO293668   CO300216   CO312121   CO333597   CO342591   CO343494   EC052099   EC056150   EC056212   EC074146   EC076194   EC197928   EC208766   EC220717   EC235761   EC251266   EC256071   EC260596   GH944642   GH952536   GH953045   GH953553   GH953765   GH956221   GH964286   GH964885   GH973830   GH976658   GH976814   GH977722   GH977990   GH978534   GH981472   Y10229 CAA71278
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	O76460
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference oogenesis     (Ghabrial et al., 1998) northern blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage -- pupal stage     (Kooistra et al., 1997) oogenesis & adult stage | female   ovary   (Kooistra et al., 1997)
Additional Descriptive Data
	okr transcripts are detected throughout development on northern blots. In adults, they are specifically expressed in the female ovary. (Kooistra et al., 1997) okr transcripts are widely distributed at all stages of oogenesis. (Ghabrial et al., 1998)
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0002989    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0002989 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0002989 expression level Developmental Stage   Expression Level embryo 00-02hr    1892 embryo 02-04hr    2016 embryo 04-06hr    2156 embryo 06-08hr    1219 embryo 08-10hr    789 embryo 10-12hr    363 embryo 12-14hr    248 embryo 14-16hr    175 embryo 16-18hr    139 embryo 18-20hr    109 embryo 20-22hr    72 embryo 22-24hr    86 larva L1    156 larva L2    159 larva L3 12hr old    166 larva L3 puffstage 1-2    184 larva L3 puffstage 3-6    258 larva L3 puffstage 7-9    298 white prepupae new    261 white prepupae 12hr    334 white prepupae 24hr    355 pupae 2d postWPP    245 pupae 3d postWPP    202 pupae 4d postWPP    165 adult male 01day    172 adult male 05day    256 adult male 30day    222 adult female 01day    602 adult female 05day    1019 adult female 30day    993 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1892) embryo 02-04hr  (2016) embryo 04-06hr  (2156) embryo 06-08hr  (1219) embryo 08-10hr  (789) embryo 10-12hr  (363) embryo 12-14hr  (248) embryo 14-16hr  (175) embryo 16-18hr  (139) embryo 18-20hr  (109) embryo 20-22hr    72 embryo 22-24hr    86 larva L1  (156) larva L2  (159) larva L3 12hr old  (166) larva L3 puffstage 1-2  (184) larva L3 puffstage 3-6  (258) larva L3 puffstage 7-9  (298) white prepupae new  (261) white prepupae 12hr  (334) white prepupae 24hr  (355) pupae 2d postWPP  (245) pupae 3d postWPP  (202) pupae 4d postWPP  (165) adult male 01day  (172) adult male 05day  (256) adult male 30day  (222) adult female 01day  (602) adult female 05day  (1019) adult female 30day  (993) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1892) embryo 02-04hr  (2016) embryo 04-06hr  (2156) embryo 06-08hr    1219 embryo 08-10hr    789 embryo 10-12hr    363 embryo 12-14hr    248 embryo 14-16hr    175 embryo 16-18hr    139 embryo 18-20hr    109 embryo 20-22hr    72 embryo 22-24hr    86 larva L1    156 larva L2    159 larva L3 12hr old    166 larva L3 puffstage 1-2    184 larva L3 puffstage 3-6    258 larva L3 puffstage 7-9    298 white prepupae new    261 white prepupae 12hr    334 white prepupae 24hr    355 pupae 2d postWPP    245 pupae 3d postWPP    202 pupae 4d postWPP    165 adult male 01day    172 adult male 05day    256 adult male 30day    222 adult female 01day    602 adult female 05day    1019 adult female 30day    993 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1892 embryo 02-04hr    2016 embryo 04-06hr    2156 embryo 06-08hr    1219 embryo 08-10hr    789 embryo 10-12hr    363 embryo 12-14hr    248 embryo 14-16hr    175 embryo 16-18hr    139 embryo 18-20hr    109 embryo 20-22hr    72 embryo 22-24hr    86 larva L1    156 larva L2    159 larva L3 12hr old    166 larva L3 puffstage 1-2    184 larva L3 puffstage 3-6    258 larva L3 puffstage 7-9    298 white prepupae new    261 white prepupae 12hr    334 white prepupae 24hr    355 pupae 2d postWPP    245 pupae 3d postWPP    202 pupae 4d postWPP    165 adult male 01day    172 adult male 05day    256 adult male 30day    222 adult female 01day    602 adult female 05day    1019 adult female 30day    993 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1892 embryo 02-04hr    2016 embryo 04-06hr    2156 embryo 06-08hr    1219 embryo 08-10hr    789 embryo 10-12hr    363 embryo 12-14hr    248 embryo 14-16hr    175 embryo 16-18hr    139 embryo 18-20hr    109 embryo 20-22hr    72 embryo 22-24hr    86 larva L1    156 larva L2    159 larva L3 12hr old    166 larva L3 puffstage 1-2    184 larva L3 puffstage 3-6    258 larva L3 puffstage 7-9    298 white prepupae new    261 white prepupae 12hr    334 white prepupae 24hr    355 pupae 2d postWPP    245 pupae 3d postWPP    202 pupae 4d postWPP    165 adult male 01day    172 adult male 05day    256 adult male 30day    222 adult female 01day    602 adult female 05day    1019 adult female 30day    993 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0002989 expression level Developmental Stage   Expression Level embryo 00-02hr    1892 embryo 02-04hr    2016 embryo 04-06hr    2156 embryo 06-08hr    1219 embryo 08-10hr    789 embryo 10-12hr    363 embryo 12-14hr    248 embryo 14-16hr    175 embryo 16-18hr    139 embryo 18-20hr    109 embryo 20-22hr    72 embryo 22-24hr    86 larva L1    156 larva L2    159 larva L3 12hr old    166 larva L3 puffstage 1-2    184 larva L3 puffstage 3-6    258 larva L3 puffstage 7-9    298 white prepupae new    261 white prepupae 12hr    334 white prepupae 24hr    355 pupae 2d postWPP    245 pupae 3d postWPP    202 pupae 4d postWPP    165 adult male 01day    172 adult male 05day    256 adult male 30day    222 adult female 01day    602 adult female 05day    1019 adult female 30day    993 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1892) embryo 02-04hr  (2016) embryo 04-06hr  (2156) embryo 06-08hr  (1219) embryo 08-10hr  (789) embryo 10-12hr  (363) embryo 12-14hr  (248) embryo 14-16hr  (175) embryo 16-18hr  139 embryo 18-20hr  109 embryo 20-22hr    72 embryo 22-24hr    86 larva L1  (156) larva L2  (159) larva L3 12hr old  (166) larva L3 puffstage 1-2  (184) larva L3 puffstage 3-6  (258) larva L3 puffstage 7-9  (298) white prepupae new  (261) white prepupae 12hr  (334) white prepupae 24hr  (355) pupae 2d postWPP  (245) pupae 3d postWPP  (202) pupae 4d postWPP  (165) adult male 01day  (172) adult male 05day  (256) adult male 30day  (222) adult female 01day  (602) adult female 05day  (1019) adult female 30day  (993) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  1892 embryo 02-04hr  2016 embryo 04-06hr  2156 embryo 06-08hr    1219 embryo 08-10hr    789 embryo 10-12hr    363 embryo 12-14hr    248 embryo 14-16hr    175 embryo 16-18hr    139 embryo 18-20hr    109 embryo 20-22hr    72 embryo 22-24hr    86 larva L1    156 larva L2    159 larva L3 12hr old    166 larva L3 puffstage 1-2    184 larva L3 puffstage 3-6    258 larva L3 puffstage 7-9    298 white prepupae new    261 white prepupae 12hr    334 white prepupae 24hr    355 pupae 2d postWPP    245 pupae 3d postWPP    202 pupae 4d postWPP    165 adult male 01day    172 adult male 05day    256 adult male 30day    222 adult female 01day    602 adult female 05day    1019 adult female 30day    993 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1892 embryo 02-04hr    2016 embryo 04-06hr    2156 embryo 06-08hr    1219 embryo 08-10hr    789 embryo 10-12hr    363 embryo 12-14hr    248 embryo 14-16hr    175 embryo 16-18hr    139 embryo 18-20hr    109 embryo 20-22hr    72 embryo 22-24hr    86 larva L1    156 larva L2    159 larva L3 12hr old    166 larva L3 puffstage 1-2    184 larva L3 puffstage 3-6    258 larva L3 puffstage 7-9    298 white prepupae new    261 white prepupae 12hr    334 white prepupae 24hr    355 pupae 2d postWPP    245 pupae 3d postWPP    202 pupae 4d postWPP    165 adult male 01day    172 adult male 05day    256 adult male 30day    222 adult female 01day    602 adult female 05day    1019 adult female 30day    993 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1892 embryo 02-04hr    2016 embryo 04-06hr    2156 embryo 06-08hr    1219 embryo 08-10hr    789 embryo 10-12hr    363 embryo 12-14hr    248 embryo 14-16hr    175 embryo 16-18hr    139 embryo 18-20hr    109 embryo 20-22hr    72 embryo 22-24hr    86 larva L1    156 larva L2    159 larva L3 12hr old    166 larva L3 puffstage 1-2    184 larva L3 puffstage 3-6    258 larva L3 puffstage 7-9    298 white prepupae new    261 white prepupae 12hr    334 white prepupae 24hr    355 pupae 2d postWPP    245 pupae 3d postWPP    202 pupae 4d postWPP    165 adult male 01day    172 adult male 05day    256 adult male 30day    222 adult female 01day    602 adult female 05day    1019 adult female 30day    993 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0002989    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0002989 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0002989 expression level Tissue   Expression Level Larval Central Nervous System    87.075 Larval Midgut    25.3 Larval Hindgut    37.1 Larval Malpighian Tubules    39.6 Larval Fat Body    39.6 Larval Salivary Gland    40.6 Larval Trachea    53.475 Larval Carcass    43.5 Adult Head    33 Adult Eye    35.05 Adult Brain    33.3 Adult Thoracic-Abdominal Ganglion    43.5 Adult Crop    46.8 Adult Midgut    28.4 Adult Hindgut    28.5 Adult Malpighian Tubules    31.2 Adult Fat Body    40.8 Adult Salivary Gland no informative data Adult Heart    33.925 Adult VirginFemale Spermatheca    37.3 Adult InseminatedFemale Spermatheca    33.2 Adult Ovary    153.1 Adult Testis    26.9 Adult Male Accessory Gland    39.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    87.075 Larval Midgut    25.3 Larval Hindgut    37.1 Larval Malpighian Tubules    39.6 Larval Fat Body    39.6 Larval Salivary Gland    40.6 Larval Trachea    53.475 Larval Carcass    43.5 Adult Head    33 Adult Eye    35.05 Adult Brain    33.3 Adult Thoracic-Abdominal Ganglion    43.5 Adult Crop    46.8 Adult Midgut    28.4 Adult Hindgut    28.5 Adult Malpighian Tubules    31.2 Adult Fat Body    40.8 Adult Salivary Gland no informative data Adult Heart    33.925 Adult VirginFemale Spermatheca    37.3 Adult InseminatedFemale Spermatheca    33.2 Adult Ovary    153.1 Adult Testis    26.9 Adult Male Accessory Gland    39.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    87.075 Larval Midgut    25.3 Larval Hindgut    37.1 Larval Malpighian Tubules    39.6 Larval Fat Body    39.6 Larval Salivary Gland    40.6 Larval Trachea    53.475 Larval Carcass    43.5 Adult Head    33 Adult Eye    35.05 Adult Brain    33.3 Adult Thoracic-Abdominal Ganglion    43.5 Adult Crop    46.8 Adult Midgut    28.4 Adult Hindgut    28.5 Adult Malpighian Tubules    31.2 Adult Fat Body    40.8 Adult Salivary Gland no informative data Adult Heart    33.925 Adult VirginFemale Spermatheca    37.3 Adult InseminatedFemale Spermatheca    33.2 Adult Ovary    153.1 Adult Testis    26.9 Adult Male Accessory Gland    39.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    87.075 Larval Midgut    25.3 Larval Hindgut    37.1 Larval Malpighian Tubules    39.6 Larval Fat Body    39.6 Larval Salivary Gland    40.6 Larval Trachea    53.475 Larval Carcass    43.5 Adult Head    33 Adult Eye    35.05 Adult Brain    33.3 Adult Thoracic-Abdominal Ganglion    43.5 Adult Crop    46.8 Adult Midgut    28.4 Adult Hindgut    28.5 Adult Malpighian Tubules    31.2 Adult Fat Body    40.8 Adult Salivary Gland no informative data Adult Heart    33.925 Adult VirginFemale Spermatheca    37.3 Adult InseminatedFemale Spermatheca    33.2 Adult Ovary    153.1 Adult Testis    26.9 Adult Male Accessory Gland    39.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0002989 expression level Tissue   Expression Level Larval Central Nervous System    87.075 Larval Midgut    25.3 Larval Hindgut    37.1 Larval Malpighian Tubules    39.6 Larval Fat Body    39.6 Larval Salivary Gland    40.6 Larval Trachea    53.475 Larval Carcass    43.5 Adult Head    33 Adult Eye    35.05 Adult Brain    33.3 Adult Thoracic-Abdominal Ganglion    43.5 Adult Crop    46.8 Adult Midgut    28.4 Adult Hindgut    28.5 Adult Malpighian Tubules    31.2 Adult Fat Body    40.8 Adult Salivary Gland no informative data Adult Heart    33.925 Adult VirginFemale Spermatheca    37.3 Adult InseminatedFemale Spermatheca    33.2 Adult Ovary    153.1 Adult Testis    26.9 Adult Male Accessory Gland    39.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    87.075 Larval Midgut    25.3 Larval Hindgut    37.1 Larval Malpighian Tubules    39.6 Larval Fat Body    39.6 Larval Salivary Gland    40.6 Larval Trachea    53.475 Larval Carcass    43.5 Adult Head    33 Adult Eye    35.05 Adult Brain    33.3 Adult Thoracic-Abdominal Ganglion    43.5 Adult Crop    46.8 Adult Midgut    28.4 Adult Hindgut    28.5 Adult Malpighian Tubules    31.2 Adult Fat Body    40.8 Adult Salivary Gland no informative data Adult Heart    33.925 Adult VirginFemale Spermatheca    37.3 Adult InseminatedFemale Spermatheca    33.2 Adult Ovary    153.1 Adult Testis    26.9 Adult Male Accessory Gland    39.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    87.075 Larval Midgut    25.3 Larval Hindgut    37.1 Larval Malpighian Tubules    39.6 Larval Fat Body    39.6 Larval Salivary Gland    40.6 Larval Trachea    53.475 Larval Carcass    43.5 Adult Head    33 Adult Eye    35.05 Adult Brain    33.3 Adult Thoracic-Abdominal Ganglion    43.5 Adult Crop    46.8 Adult Midgut    28.4 Adult Hindgut    28.5 Adult Malpighian Tubules    31.2 Adult Fat Body    40.8 Adult Salivary Gland no informative data Adult Heart    33.925 Adult VirginFemale Spermatheca    37.3 Adult InseminatedFemale Spermatheca    33.2 Adult Ovary    153.1 Adult Testis    26.9 Adult Male Accessory Gland    39.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    87.075 Larval Midgut    25.3 Larval Hindgut    37.1 Larval Malpighian Tubules    39.6 Larval Fat Body    39.6 Larval Salivary Gland    40.6 Larval Trachea    53.475 Larval Carcass    43.5 Adult Head    33 Adult Eye    35.05 Adult Brain    33.3 Adult Thoracic-Abdominal Ganglion    43.5 Adult Crop    46.8 Adult Midgut    28.4 Adult Hindgut    28.5 Adult Malpighian Tubules    31.2 Adult Fat Body    40.8 Adult Salivary Gland no informative data Adult Heart    33.925 Adult VirginFemale Spermatheca    37.3 Adult InseminatedFemale Spermatheca    33.2 Adult Ovary    153.1 Adult Testis    26.9 Adult Male Accessory Gland    39.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    33   NA  Eye    35.05   NA  Brain    33.3   87.075  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    43.5   NA  Crop    46.8   25.3  Midgut    28.4   37.1  Hindgut    28.5   39.6  Malpighian Tubules    31.2   39.6  Fat Body    40.8   40.6  Salivary Gland    no informative data   NA  Heart    33.925   53.475  Trachea    NA   NA  VirginFemale Spermatheca    37.3   NA  InseminatedFemale Spermatheca    33.2   NA  Ovary    153.1   NA  Testis    26.9   NA  Male Accessory Gland    39.6   43.5  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_06
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0002989 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3736-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable okr17-11 okrAA okrAB okrAG okrAK okrAO okrRU okrWS okrZII-5130 viable, with Scer\GAL4pnr-MD237 okrGD4181 Sterility Allele female fertile | reduced okrAO female sterile okr17-11 okrA19-10 okrRU okrWS female sterile | recessive okr17-11 fertile okr782 male fertile okr17-11 sterile okrWS Other Phenotypes Allele chemical sensitive okrRU okrZII-5130 chemical sensitive (with okrAA) okrRU chemical sensitive (with okrRU) okrAA chemical sensitive | maternal effect okr17-11 chemical sensitive | recessive okr17-11 okrA19-10 okrAA okrWS DNA repair defective okrRU DNA repair defective (with okrAA) okrRU DNA repair defective (with okrRU) okrAA meiotic cell cycle defective okr782 radiation sensitive okr17-11 okrRU radiation sensitive (with okrAA) okrRU radiation sensitive (with okrRU) okrAA radiation sensitive | embryonic stage | rescuable maternal effect (with Df(2L)JS17) okr782 radiation sensitive | maternal effect okr17-11 radiation sensitive | recessive okr17-11 okrA19-10 wild-type okr+t4.7 Phenotype manifest in Allele chorion (with okrAA) okrRU chorion (with okrRU) okrAA chorion | maternal effect okrRU chorion | maternal effect (with okrAA) okrRU chorion | maternal effect (with okrRU) okrAA dorsal appendage okrAA okrAB okrRU okrunspecified egg okrAA eye disc | conditional okr17-11 follicle cell okrAB karyosome okrunspecified metaphase & condensed nuclear chromosome | conditional qualifier okr17-11 micropyle okrAB nucleus okrAA oocyte okrAA presumptive oocyte okrWS
Classical Alleles ( 12 )
For All Classical Alleles Show
Allele of okr Class Mutagen Stocks Known lesion okrRU antimorphic allele - genetic evidence ethyl methanesulfonate 2 Yes okr17-11 loss of function allele ethyl methanesulfonate 1 Yes okrA19-10 1 Yes okr782 X ray 0 -- okrAA loss of function allele ethyl methanesulfonate 0 Yes okrAB antimorphic allele - genetic evidence ethyl methanesulfonate 0 Yes okrAG loss of function allele ethyl methanesulfonate 0 Yes okrAK antimorphic allele - genetic evidence ethyl methanesulfonate 0 Yes okrAO antimorphic allele - genetic evidence ethyl methanesulfonate 0 Yes okrunspecified 0 -- okrWS antimorphic allele - genetic evidence ethyl methanesulfonate 0 Yes okrZII-5130 ethyl methanesulfonate 0 --
Alleles Carried on Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Allele of okr Class Mutagen Stocks Known lesion okrGD4181 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes okrHMS00585 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes okrJF01286 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes okrJF01494 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes okrKK107487 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes okr+t4.7 in vitro construct - genomic fragment 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)AS8 (Ferro, 2002.12) Df(2L)Exel7014 (Ryder, 2004.4.26) Df(2L)JS17 (Ghabrial et al., 1998, Eeken et al., 1997, Kooistra et al., 1997)
Not disrupted in	Df(2L)C144 (Ghabrial et al., 1998) Df(2L)JS7 (Ghabrial et al., 1998)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4181} NA P{KK107487} NA P{TRiP.HMS00585} NA P{TRiP.JF01286} NA P{TRiP.JF01494} NA characterization construct P{RRa54E4.7} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 14 unique terms )
Terms Based on Experimental Evidence ( 5 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
dorsal appendage formation inferred from mutant phenotype (Schupbach and Wieschaus, 1991) double-strand break repair inferred from mutant phenotype (Kooistra et al., 1997) double-strand break repair via synthesis-dependent strand annealing inferred from mutant phenotype (Wei and Rong, 2007) oogenesis inferred from genetic interaction with p53 (Lu et al., 2010) inferred from mutant phenotype (Schupbach and Wieschaus, 1991) response to ionizing radiation inferred from mutant phenotype (Gorski et al., 2003)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 11 terms )
Molecular Function
CV term Evidence References
ATP binding inferred from electronic annotation with InterPro:IPR000330, InterPro:IPR001650 (FlyBase Curators et al., 2004-) ATP-dependent DNA helicase activity inferred from sequence or structural similarity (Ghabrial et al., 1998) inferred from sequence or structural similarity with Saccharomyces RAD54 (FlyBase, 1992-) DNA binding inferred from electronic annotation with InterPro:IPR000330 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
chromosome condensation traceable author statement (van Eeden and St. Johnston, 1999) DNA recombination inferred from sequence or structural similarity (Kooistra et al., 1997) DNA repair non-traceable author statement (van Eeden and St. Johnston, 1999) double-strand break repair traceable author statement (Lee and Orr-Weaver, 2003) intracellular mRNA localization traceable author statement (Cooperstock and Lipshitz, 1997) oogenesis traceable author statement (van Eeden and St. Johnston, 1999) reciprocal meiotic recombination traceable author statement (Morris and Lehmann, 1999, van Eeden and St. Johnston, 1999) regulation of translation traceable author statement (Cooperstock and Lipshitz, 1997)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions okr allele Gene References okr17-11 Lig4 (Gorski et al., 2003) mus309 (Kooistra et al., 1999) okrA19-10 mus309 (Kooistra et al., 1999) okrAA mei-W68 (Ghabrial and Schupbach, 1999) okrRU mei-41 (Ghabrial and Schupbach, 1999) mei-W68 (Ghabrial and Schupbach, 1999) okrunspecified c(3)G (Ghabrial and Schupbach, 1999) mei-P22 (Ghabrial and Schupbach, 1999)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59726 DroID - A comprehensive database of gene and protein interactions. • FBgn0002989 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33507
Orthologs
Genome-wide drosophilid orthologs	Dana\GF14336 Dere\GG24469 Dgri\GH10642 Dmoj\GI10760 Dper\GL26701 Dpse\GA17651 Dsec\GM18177 Dsim\GD12001 Dvir\GJ18280 Dwil\GK15573 Dyak\GE14966
Curated drosophilid orthologs	Dpse\GA17651   Dsim\okr (Anderson et al., 2009)
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL002647-PA Aedes aegypti (mosquito) AGAP008748-PA Anopheles gambiae (mosquito) XP_392959.3 Apis mellifera (honey bee) XP_001948023.1 Acyrthosiphon pisum (pea aphid) At3g19210.1 Arabidopsis thaliana (wall cress) 12619 Batrachochytrium dendrobatidis (chytrid fungus) 286317 Branchiostoma floridae (lancelet) XP_001895355.1 Brugia malayi (roundworm nematode) BGIBMGA013073-PA Bombyx mori (silk worm) ENSBTAP00000026513 Bos taurus (bovine) CAL0001568 Candida albicans (a form of yeast) CN12666 Caenorhabditis brenneri (small nematode) CBP31186 Caenorhabditis briggsae (nematode) CE25143 Caenorhabditis elegans (worm) ENSCAFP00000006360 Canis familiaris (dog) CAGL0I04224g Candida glabrata (haploid yeast) Chro.10140 Cryptosporidium hominis (obligate parasite) JA08288 Caenorhabditis japonica (nematode) cn04353 Cryptococcus neoformans (yeast-like fungus) cgd1_1180 Cryptosporidium parvum (protozoan parasite) CPIJ006602 Culex pipens (mosquito) ENSCPOP00000006099 Cavia porcellus (guinea pig) 111277 Chlamidomonas reinhardtii (green alga) RP36949 Caenorhabditis remanei (nematode) ENSCSAVP00000018504 Ciona savignyi (sedentary tunicate) DDB0232369 Dictyostelium discoideum (amoeba) DEHA2D05456g Debaryomyces Hansenii (yeast) 306273 Daphnia pulex (daphnia) ENSDARP00000087944 Danio rerio (zebra fish) ENSECAP00000007026 Equus caballus (horse) XP_653352 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000004082 Gymnopilus aculeatus (mushroom) ENSGALP00000037559 Gallus gallus (chicken) 157121 Hypsipyla robusta (cedar shoot borer) ENSP00000361043 Homo sapiens (human) ISCW020653-PA Ixodes scapularis (deer tick) KLLA0A03069g Kluyveromyces lactis (yeast) 220456 Lottia gigantea (owl limpet) LmjF24.0760 Leishmania major (virus) 10186 Monocosta brevicollis (choanoflagellate) ENSMODP00000002477 Monodelphis domestica (gray opossum) ENSMMUP00000007478 Macaca mulatta (rhesus monkey) ENSMUSP00000099766 Mus musculus (house mouse) 171328 Nematostella vectensis (starlet anemone) XP_001601964.1 Nasonia vitripennis (wasp) ENSOANP00000017983 Ornithorynchus anatinus (platypus) ENSORLP00000003700 Oryzias latipes (japanese killifish) LOC_Os02g52510.1 Oryza sativa (asian rice) 18619 Ostreococcus tauri (green alga) PF08_0126 Plasmodium falciparum (protozoal parasite) PHUM005201-PA Pediculus humanus (human body louse) 21176 Physcomitrella patens (moss) ENSPPYP00000001622 Pongo pygmaeus (orangutan) 38878 Phytophthora ramorum (sudden oak death pathogen) 112767 Phytophthora sojae (root rot pathogen) 267841 Populus trichocarpa (black cottonwood) ENSPTRP00000001196 Pan troglodytes (chimpanzee) PVX_093575 Plasmodium vivax (protozoal parasite) ENSRNOP00000018004 Rattus norvegicus (norway rat) 4868945 Sorghum bicolor (sorghum) YGL163C Saccharomyces cerevisiae (budding yeast) SPAC15A10.03c Schizosaccharomyces pombe (fission yeast) XP_783733.1 Strongylocentrotus purpuratus (purple sea urchin) 27976 Trichoplax adhaerens (metazoa) TA05745 Theileria annulata (apicomplexan parasite) XP_967988.2 Tribolium castaneum (red flour beetle) Tc00.1047053505183.40 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053508647.290 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000007369 Tetraodon nigroviridis (green spotted pufferfish) TP01_0805 Theileria parva (parasitic protozoan) 12846 Thalassiosira pseudonana (marine diatom) ENSTRUP00000021061 Takifugu rubripes (pufferfish Takifugu) 3706.m00024 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000009513 Xenopus tropicalis (frog) YALI0B07513g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV15510 LH18183 ISCW020653 FBgn0232556 FBgn0217578 FBgn0205441 FBgn0183740 FBgn0173084 JGI_V11_306273 FBgn0077662 FBgn0164282 FBgn0133523 FBgn0118123 FBgn0116601 FBgn0091363 CPIJ006602 BGIBMGA013073 ACYPI001697 GB16633 AGAP008748 AAEL002647 PB22515 PHUM513160 GLEAN_15104
Stocks & Reagents
Stocks Listed in FlyBase ( 10 )
Bloomington	31047 y1 v1; P{TRiP.JF01494}attP2 31329 y1 v1; P{TRiP.JF01286}attP2 8524 okr17-11 cn1 bw1/CyO 8525 okrA19-10 cn1 bw1/CyO 33707 y1 sc* v1; P{TRiP.HMS00585}attP2 5098 okrRU cn1 bw1/CyO, l(2)DTS5131
Kyoto	108040 okrRU cn1 bw1/CyO, l(2)DTS5131
VDRC	v104323 P{KK107487}VIE-260B v30470 w1118; P{GD4181}v30470 v30472 w1118; P{GD4181}v30472/TM3
Genomic Clones ( 1 )
	BACR23N06 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 29 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD35220
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LP04224 LP12840
Other clones	EC052099 EC056150 EC056212 EK100222 EK164740 EK177632 EK204054 EK227910 EK307414 EP15156 EP16860 RP004083166 RP004125219 RP004127506 RP004135835 RP004143442 RP004231549 RP004238647 RP004258582 RP004265913 RP004281039 RP004309867 RP004314058 RP004374921 RP004498088 RP004505854
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0002989 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33507
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	Gene is involved in post-replication recombination repair. (de Buendia, 1998) Characterisation of mutants implies okr is crucial in repair and recombination. (Kooistra et al., 1997) Mutant phenotype is consistent with a defect in the repair of double-stranded breaks. (Kooistra et al., 1997) Mutations at the okr locus cause defects in midoogenesis. (Schupbach and Wieschaus, 1991)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_057313 RefSeq (Proteins) • NP_476661 DDBJ / EMBL / GenBank • AAC24577 AAC26857 AAF51168 AAL39744 AC010009 AC092187 AF069779 AF069780 AI518818 AW943269 AY069599 CAA71278 Y10229 Entrez Gene - A searchable database of RefSeq genes. • 33507 UniProtKB/TrEMBL • O76460
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • SNF2-related (IPR000330) Helicase, C-terminal (IPR001650) DEAD-like helicase (IPR014001) Rad54, N-terminal (IPR013967)
Linkouts
	BioGRID - A database of protein and genetic interactions • 59726 DroID - A comprehensive database of gene and protein interactions. • FBgn0002989 DRSC - Results from RNAi screens. • FBgn0002989 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0002989 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3736-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0002989 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33507 InParanoid A subset of ortholog calls from InParanoid. • AAEL002647-PA Aedes aegypti (mosquito) AGAP008748-PA Anopheles gambiae (mosquito) XP_392959.3 Apis mellifera (honey bee) XP_001948023.1 Acyrthosiphon pisum (pea aphid) At3g19210.1 Arabidopsis thaliana (wall cress) 12619 Batrachochytrium dendrobatidis (chytrid fungus) 286317 Branchiostoma floridae (lancelet) XP_001895355.1 Brugia malayi (roundworm nematode) BGIBMGA013073-PA Bombyx mori (silk worm) ENSBTAP00000026513 Bos taurus (bovine) CAL0001568 Candida albicans (a form of yeast) CN12666 Caenorhabditis brenneri (small nematode) CBP31186 Caenorhabditis briggsae (nematode) CE25143 Caenorhabditis elegans (worm) ENSCAFP00000006360 Canis familiaris (dog) CAGL0I04224g Candida glabrata (haploid yeast) Chro.10140 Cryptosporidium hominis (obligate parasite) JA08288 Caenorhabditis japonica (nematode) cn04353 Cryptococcus neoformans (yeast-like fungus) cgd1_1180 Cryptosporidium parvum (protozoan parasite) CPIJ006602 Culex pipens (mosquito) ENSCPOP00000006099 Cavia porcellus (guinea pig) 111277 Chlamidomonas reinhardtii (green alga) RP36949 Caenorhabditis remanei (nematode) ENSCSAVP00000018504 Ciona savignyi (sedentary tunicate) DDB0232369 Dictyostelium discoideum (amoeba) DEHA2D05456g Debaryomyces Hansenii (yeast) 306273 Daphnia pulex (daphnia) ENSDARP00000087944 Danio rerio (zebra fish) ENSECAP00000007026 Equus caballus (horse) XP_653352 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000004082 Gymnopilus aculeatus (mushroom) ENSGALP00000037559 Gallus gallus (chicken) 157121 Hypsipyla robusta (cedar shoot borer) ENSP00000361043 Homo sapiens (human) ISCW020653-PA Ixodes scapularis (deer tick) KLLA0A03069g Kluyveromyces lactis (yeast) 220456 Lottia gigantea (owl limpet) LmjF24.0760 Leishmania major (virus) 10186 Monocosta brevicollis (choanoflagellate) ENSMODP00000002477 Monodelphis domestica (gray opossum) ENSMMUP00000007478 Macaca mulatta (rhesus monkey) ENSMUSP00000099766 Mus musculus (house mouse) 171328 Nematostella vectensis (starlet anemone) XP_001601964.1 Nasonia vitripennis (wasp) ENSOANP00000017983 Ornithorynchus anatinus (platypus) ENSORLP00000003700 Oryzias latipes (japanese killifish) LOC_Os02g52510.1 Oryza sativa (asian rice) 18619 Ostreococcus tauri (green alga) PF08_0126 Plasmodium falciparum (protozoal parasite) PHUM005201-PA Pediculus humanus (human body louse) 21176 Physcomitrella patens (moss) ENSPPYP00000001622 Pongo pygmaeus (orangutan) 38878 Phytophthora ramorum (sudden oak death pathogen) 112767 Phytophthora sojae (root rot pathogen) 267841 Populus trichocarpa (black cottonwood) ENSPTRP00000001196 Pan troglodytes (chimpanzee) PVX_093575 Plasmodium vivax (protozoal parasite) ENSRNOP00000018004 Rattus norvegicus (norway rat) 4868945 Sorghum bicolor (sorghum) YGL163C Saccharomyces cerevisiae (budding yeast) SPAC15A10.03c Schizosaccharomyces pombe (fission yeast) XP_783733.1 Strongylocentrotus purpuratus (purple sea urchin) 27976 Trichoplax adhaerens (metazoa) TA05745 Theileria annulata (apicomplexan parasite) XP_967988.2 Tribolium castaneum (red flour beetle) Tc00.1047053505183.40 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053508647.290 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000007369 Tetraodon nigroviridis (green spotted pufferfish) TP01_0805 Theileria parva (parasitic protozoan) 12846 Thalassiosira pseudonana (marine diatom) ENSTRUP00000021061 Takifugu rubripes (pufferfish Takifugu) 3706.m00024 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000009513 Xenopus tropicalis (frog) YALI0B07513g Yarrowia lipolytica (nonconventional yeast) Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /polycomb/okra1.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33507 modMine - Data generated by the modENCODE project. • FBgn0002989 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV15510 LH18183 ISCW020653 FBgn0232556 FBgn0217578 FBgn0205441 FBgn0183740 FBgn0173084 JGI_V11_306273 FBgn0077662 FBgn0164282 FBgn0133523 FBgn0118123 FBgn0116601 FBgn0091363 CPIJ006602 BGIBMGA013073 ACYPI001697 GB16633 AGAP008748 AAEL002647 PB22515 PHUM513160 GLEAN_15104
Synonyms & Secondary IDs ( 13 )
Reported As
Symbol Synonym	CG3736 (Spellman and Rubin, 2002, Keleman et al., 2009.8.5, Schneiderman et al., 2009, Ni et al., 2008, Ni et al., 2010.12.1) DhR54 (de Buendia, 1998) DmRad54 (Pastink and Lohman, 1999, Eeken et al., 1999) DmRAD54 (Kooistra et al., 1999, Kooistra et al., 1998, Kooistra et al., 1997, Eeken et al., 1997) Dmrad54 (Abdu et al., 2007) okr (Spellman and Rubin, 2002, Barbosa et al., 2007, Mehrotra and McKim, 2006, Wei and Rong, 2007, Jang et al., 2003, Joyce and McKim, 2009, Anderson et al., 2009, Bozas et al., 2009, Schneiderman et al., 2009, Lu et al., 2010, Reis et al., 2011, Johnson-Schlitz et al., 2007, Lake et al., 2011) okra (Holmes et al., 2006, Hochwagen, 2006, Abdu et al., 2007) rad54 (Romeijn, 2005, Jaklevic and Su, 2002, Johnson-Schlitz et al., 2007, Klovstad et al., 2008, Lu et al., 2010) Rad54 (Alexiadis et al., 2004, Gorski et al., 2003, Alexiadis and Kadonaga, 2002, Bozas and Carroll, 2006, Holmes et al., 2006, Jang et al., 2003, Bozas et al., 2009) RAD54 (Vijg, 2002, Pastink, 1996.12.20, Pastink et al., 2001) RAD54L (Somma et al., 2008) Ras54 (Wei and Rong, 2007)
Name Synonym	Okra (Pedersen et al., 2008) okra (Ghabrial, 1998.6.2, Klovstad et al., 2008, Somma et al., 2008, Vázquez et al., 2008, McDaniel et al., 2008, Joyce and McKim, 2009, Lu et al., 2010, Lake et al., 2011)
Secondary FlyBase IDs
	FBgn0017554
References ( 92 )
Generate a list of	All references relating to this gene ( 92 )
List References by type	Research paper  ( 42 ) Supplementary material  ( 3 ) Review  ( 15 ) Personal communication to FlyBase  ( 6 ) Abstract  ( 17 ) FlyBase analysis  ( 2 ) Biography  ( 1 ) DNA/RNA sequence record  ( 3 ) Computer file  ( 1 ) Curated genome annotation  ( 1 ) Automatic genome annotation  ( 1 )
Recent research papers ( 4 )
	Chiolo et al., 2011, Cell 144(5): 732--744 Double-Strand Breaks in Heterochromatin Move Outside of a Dynamic HP1a Domain to Complete Recombinational Repair. [FBrf0213146] Lake et al., 2011, PLoS Genet. 7(2): e1002005 The Drosophila zinc finger protein trade embargo is required for double strand break formation in meiosis. [FBrf0213142] Reis et al., 2011, PLoS ONE 6(3): e17512 Drosophila Genes That Affect Meiosis Duration Are among the Meiosis Related Genes That Are More Often Found Duplicated. [FBrf0213266] Lu et al., 2010, Science 328(5983): 1278--1281 Meiotic recombination provokes functional activation of the p53 regulatory network. [FBrf0210965] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...