Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.49
None of the polypeptides share 100% sequence identity.
640 (aa); 74 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\phr using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\phr in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: phr anon-OV1
"CG18853" is a putative chimeric gene derived from the "CG12822" and "phr" genes (where coding sequences of the two parental genes contribute to the coding sequence of the chimeric gene).
Gene is involved in pre-replication DNA repair of UV and AA lesions and photorepair.
Biochemical and photochemical characterisation of purified phr. Studies reveal the protein belongs to the folate class of enzymes.
Drosophila have two types of photolyase, the substrate of each photolyase is completely different. Photolyase repairs UV induced DNA damage, the two types of DNA damage are cyclobutane pyrimidine dimer (CPD) and (6-4) photoproduct. phr encodes the photolyase that specifically repairs CPD.
phr gene product preferentially binds to unusual DNA structures and is UV inducible.
Encodes a photolyase that repairs cyclobutane pyrimidine dimers induced by UV radiation of DNA.