Gene model reviewed during 5.44
Gene model reviewed during 5.52
2.0 (northern blot)
303 (aa); 34.7 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\PpV using the Feature Mapper tool.
Northern blots show that the PpV transcript is expressed at high levels in 0-4 hours of embryogenesis, and is present at low levels at other developmental stages. PpV transcript is detected in late synytial blastoderm-early cellular blastoderm stage embryos, in the cytoplasm. PpV transcript is not easily detectable in embryos before or after this stage.
GBrowse - Visual display of RNA-Seq signalsView Dmel\PpV in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
PpV was identified by sequence similarity to Pp1-87B. Complementation studies indicate that it can functionally rescue a temperature sensitive yeast mutant, SIT4. The pattern and timing of PpV expression in the embryo suggests it may play a role in the introduction of a G2 phase in the cell cycle, elevated zygotic transcription or cellularization.