Gene model reviewed during 5.43
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.52
There is only one protein coding transcript and one polypeptide associated with this gene
168 (aa); 19 (kD observed)
Homohexamer formed of two homotrimers in a head to head fashion.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\pr using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\pr in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Transcription unit identified during molecular analysis of the neb genomic region.
The enzyme sepiapterin synthase A, is involved in early steps leading to the synthesis of the drosopterins.
Mutants deficient in pteridines. Sepiapterin and the drosopterins are markedly reduced relative to wild type in pr1 and prbw, the effect being greater in prbw than in pr1. The suppressors su(s)2 and su(pr)3 restore the pyrimidine level of pr1 and prbw to that of wild-type or nearly wild-type.
Mutants deficient in pteridines. When pr+ has been translocated into the Y chromosome <up>T(Y;2)prC5</up>, the T(Y;2)prC5, cn1/prC4, cn1 flies show a variegated eye color. The suppressors su(s)2 and su(pr)3 restore the pyrimidine level of pr1 and prbw to that of wild-type or nearly wild-type.
Mutants deficient in pteridines.
Eye color ruby at hatching, darkening to purplish ruby with age.
Larval Malpighian tubules wild-type in color.