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Gene Dmel\Rex

General Information
Symbol	Dmel\Rex	Species	D. melanogaster
Name	Ribosomal exchange	Annotation symbol
Feature type	gene	FlyBase ID	FBgn0003239
Gene Model Status	Unannotated	Stock availability	1 publicly available
Genomic Location
Chromosome (arm)		Recombination map	1-66
Cytogenetic map	20F1-h32	Sequence location
Summary Information
Automatically generated summary See sections below for more information	The gene Ribosomal exchange is referred to in FlyBase by the symbol Dmel\Rex (FBgn0003239). It is a gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has no annotated transcripts. Gene has not been localized to the genome sequence.
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	Rex: Ribosomal exchange (L. Robbins) Semi-dominant, maternal-effect locus which causes an early mitotic exchange between blocks of rDNA in 1 to 10% of the offspring of Rex-bearing females. Rex affects chromosomes with two separated, complete or partial ribosomal-DNA regions, such as YSX.YL or In(1)scS1Lsc4R. Chromosomes having separated blocks of heterochromatin that do not both include ribosomal genes, such as In(1)wm4, are insensitive. Affected chromosomes may pair in either spiral or hairpin configurations; the former results in loss of the intervening material (e.g., YbbRex, Dp(1;f)scS1Lsc4R, Dp(1;f)wm51bLwm4R), the latter in the inversion of that material (Dp(1;1)scS1Lsc4R, Dp(1;1)wm51bLwm4R) (Robbins and Swanson, 1988, Genetics 120: 1053-59). Exchanges usually occur early enough to yield whole-body recombinant genotypes, but a minority of events yield half-half mosaics. The exchange event generally results in partial deletion of rDNA (Robbins).
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Unknown gene gene name
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 20F1-h32   Left limit from recombination mapping relative to su(f) (FBrf0054128) Right limit from (method unavailable) (citation unavailable)
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location	1-66
Left of (cM)
Right of (cM)	su(f) (Rasooly and Robbins, 1991)
Notes	Mapped by Rasooly.
Gene Model & Products
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa)
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Mapped Features
Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
Expression Clusters
External Data & Images
Linkouts
Alleles & Phenotypes
Summary of Allele Phenotypes
Other Phenotypes Allele mitotic cell cycle defective | maternal effect | semidominant Rex1 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of Rex Class Mutagen Stocks Known lesion Rex1 spontaneous 1 --
Alleles Carried on Transgenic Constructs ( 0 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Rex Class Mutagen Stocks Known lesion
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Rex allele Gene References
External Data
Linkouts
Orthologs
Genome-wide drosophilid orthologs
Curated drosophilid orthologs
Linkouts
Stocks & Reagents
Stocks Listed in FlyBase ( 1 )
Bloomington	4290 y1 cv1 v1 f1 Rex1/C(1)DX, y1 f1
Genomic Clones ( 0 )
cDNA Clones ( 0 )
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts	GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 45353
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	All of the cytological damage caused by Rex-induced recombination can be accounted for by damage to the rDNA and the rest of the genome, if it is at all sensitive to Rex, is far less sensitive than is the rDNA. (Robbins, 1996) Rex is a genetically identified repeated element within the rDNA which has a semidominant maternal effect that promoter exchange within and between rDNA arrays in the first few embryonic mitoses. Genetic properties suggest the primary effect of Rex is rDNA-specific chromosome breakage that is resolved by recombination. (Robbins and Pimpinelli, 1994)
External Crossreferences & Linkouts
Sequence Crossreferences
Other Crossreferences
Linkouts
	GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 45353
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Rex   Su(Rex) (Gatti and Pimpinelli, 1992, )
Name Synonym	Ribosomal exchange
Secondary FlyBase IDs
References ( 13 )
Research paper	Robbins, 2000, Genetics 154(1): 13--26 Do-it-yourself statistics: a computer-assisted likelihood approach to analysis of data from genetic crosses. [FBrf0125172] Robbins, 1996, Genetics 144(1): 109--115 Specificity of chromosome damage caused by the rex element of Drosophila melanogaster. [FBrf0089797] Robbins and Pimpinelli, 1994, Genetics 138(2): 401--411 Chromosome damage and early developmental arrest caused by the Rex element of Drosophila melanogaster. [FBrf0076548] Rasooly and Robbins, 1991, Genetics 129: 119--132 Rex and a suppressor of Rex are repeated neomorphic loci in the Drosophila melanogaster ribosomal DNA. [FBrf0054128] Rasooly and Robbins, 1991, D. I. S. 70: 185--186 Mitotic instability of a P-element ribosomal cistron insertion. [FBrf0053581] Robbins and Swanson, 1988, Genetics 120: 1053--1059 Rex-induced recombination implies bipolar organization of the ribosomal RNA genes of Drosophila melanogaster. [FBrf0048189] Swanson, 1987, Genetics 115: 271--276 The responding site of the Rex locus of Drosophila melanogaster. [FBrf0046361] Robbins, 1981, Genetics 99(34): 443--459 Genetically induced mitotic exchange in the heterochromatin of Drosophila melanogaster. [FBrf0036521]
Review	Gatti and Pimpinelli, 1992, A. Rev. Genet. 26: 239--275 Functional elements in Drosophila melanogaster heterochromatin. [FBrf0055232] Robbins, 1992, Lindsley, Zimm, 1992: 585 Entry for Rex [FBrf0056735] Williams and Robbins, 1992, Trends Genet. 8(10): 335--340 Molecular genetic analysis of Drosophila rDNA arrays. [FBrf0057721]
Abstract	Robbins et al., 2001, Europ. Dros. Res. Conf. 17: A3 Rex and the naked nucleolus organizer - characterization of some useful recombinant rDNA arrays. [FBrf0137879]
Thesis	Swanson, 1984, Ph.D. Thesis, Michigan State University, MI: vii + 106pp Parameters of the Rex phenotype in Drosophila melanogaster. [FBrf0064875]