FB2020_01, released Feb 12, 2020

Gene: Dmel\rib

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General Information
Symbol
Dmel\rib
Species
D. melanogaster
Name
ribbon
Annotation Symbol
CG7230
Feature Type
protein_coding_gene
FlyBase ID
FBgn0003254
Gene Model Status
Current
Stock Availability
8 publicly available
Gene Snapshot
ribbon (rib) encodes a nuclear BTB-domain protein, expressed in most embryonic cells. It is required for development of the salivary gland and trachea, as well as for dorsal closure. It regulates both growth and differentiation of salivary gland cells. [Date last reviewed: 2019-03-14]
Other Summaries
Key Links
Genomic Location
Cytogenetic map
56C6-56C6
Sequence location
2R:19,270,078..19,281,396 [+]
Recombination map

2-88

RefSeq locus
NT_033778 REGION:19270078..19281396
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Molecular Function (GO)
[Detailed GO annotations]
Experimental Evidence
-
Predictions / Assertions
DNA binding; DNA-binding transcription factor activity
Summaries
Gene Group (FlyBase)
PIPSQUEAK TRANSCRIPTION FACTORS -
Pipsqueak transcription factors are sequence-specific DNA binding proteins that regulate transcription. These family members are characterized by a heix-turn-helix DNA-binding domain called Psq domain, which consists of four tandem repeats of a conserved 50-amino acid sequence, the Psq motif. (Adapted from FBrf0148954 and FBrf0105267).
Phenotypic Description (Red Book; Lindsley and Zimm 1992)
rib: ribbon
Homozygous embryonic lethal; lateral extents of belts narrow; fusion of adjacent dentical bands in ventral midline; dorsal closure defective.
Summary (Interactive Fly)

BTB/POZ domain transcription factor - a regulator of epithelial morphogenesis that promotes cell migration - regulates morphogenesis of the embryonic salivary gland through transcriptional activation and repression

Gene Model and Products
Number of Transcripts
3
Number of Unique Polypeptides
2

Please see the GBrowse view of Dmel\rib or the JBrowse view of Dmel\rib for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

gene_with_stop_codon_read_through ; SO:0000697

Stop-codon suppression (UGA) postulated; FBrf0216884

Gene model reviewed during 5.44

Gene model reviewed during 5.50

A non-AUG start codon may be used for translation of one or more transcripts of this gene; based on the presence of conserved protein signatures within the 5' UTR without an in-frame AUG (FBrf0243886).

Sequence Ontology: Class of Gene
gene_with_stop_codon_read_through
(Jungreis et al., 2011)
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
rib-RA
FBtr0086512
NM_080534
3956
661
rib-RB
FBtr0330057
NM_001274155
4244
661
rib-RC
FBtr0330058
NM_001274156
3956
680
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
rib-PA
FBpp0085700
71.0
661
6.61
NP_536795
AAF57588
rib-PB
FBpp0303090
71.0
661
6.61
NP_001261084
AGB93616
rib-PC
FBpp0303091
73.1
680
6.46
NP_001261085
AGB93617
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

661 aa isoforms: rib-PA, rib-PB
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Nucleotide / Polypeptide Records
 
UniProt
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\rib using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Gene Ontology (23 terms)
Molecular Function (2 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
DNA binding
inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR009057
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
DNA-binding transcription factor activity
traceable author statement
(Sudarsan, 2003)
Biological Process (20 terms)
Terms Based on Experimental Evidence (14 terms)
CV Term
Evidence
References
central nervous system development
inferred from mutant phenotype
(Jack and Myette, 1997)
dorsal closure
inferred from mutant phenotype
(Blake et al., 1998)
epithelial cell migration, open tracheal system
inferred from mutant phenotype
(Bradley and Andrew, 2001, Shim et al., 2001)
establishment or maintenance of epithelial cell apical/basal polarity
inferred from mutant phenotype
(Kerman et al., 2008)
gonad development
inferred from mutant phenotype
(Weyers et al., 2011)
head involution
inferred from mutant phenotype
(Jack and Myette, 1997)
hindgut morphogenesis
inferred from mutant phenotype
(Blake et al., 1998, Jack and Myette, 1997)
Malpighian tubule morphogenesis
inferred from mutant phenotype
(Jack and Myette, 1997)
open tracheal system development
inferred from mutant phenotype
(Jack and Myette, 1997)
protein localization
inferred from mutant phenotype
(Blake et al., 1998)
regulation of cell shape
inferred from mutant phenotype
(Blake et al., 1998, Jack and Myette, 1997)
regulation of Malpighian tubule diameter
inferred from mutant phenotype
(Jack and Myette, 1997)
salivary gland morphogenesis
inferred from mutant phenotype
(Kerman et al., 2008, Blake et al., 1998, Jack and Myette, 1997)
tracheal outgrowth, open tracheal system
inferred from mutant phenotype
(Kerman et al., 2008)
Terms Based on Predictions or Assertions (10 terms)
CV Term
Evidence
References
cell migration
traceable author statement
(Abrams et al., 2003, Bradley et al., 2001)
cytoskeleton organization
traceable author statement
(Harden, 2002)
dorsal closure
non-traceable author statement
(Abrams et al., 2003)
traceable author statement
(Harden, 2002, Noselli and Agnes, 1999)
membrane organization
traceable author statement
(Sudarsan, 2003)
open tracheal system development
non-traceable author statement
(Abrams et al., 2003)
traceable author statement
(Sudarsan, 2003)
regulation of cell shape
traceable author statement
(Bradley et al., 2001)
regulation of transcription by RNA polymerase II
inferred from biological aspect of ancestor with PANTHER:PTN001135010
(assigned by GO_Central )
(Gaudet et al., 2011)
regulation of transcription, DNA-templated
traceable author statement
(Sudarsan, 2003)
salivary gland development
traceable author statement
(Abrams et al., 2003, Sudarsan, 2003)
salivary gland morphogenesis
non-traceable author statement
(Bradley et al., 2001)
Cellular Component (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
nucleus
inferred from direct assay
(Shim et al., 2001)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
nucleus
inferred from biological aspect of ancestor with PANTHER:PTN001135010
(assigned by GO_Central )
(Gaudet et al., 2011)
traceable author statement
(Sudarsan, 2003)
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 4
epithelial cell
(Lecuyer et al., 2007)
epithelium
(Lecuyer et al., 2007)
embryonic stage 4 -- 6
foregut anlage in statu nascendi
(Fisher et al., 2012)
hindgut anlage in statu nascendi
(Fisher et al., 2012)
posterior ectoderm anlage

Comment: anlage in statu nascendi

(Fisher et al., 2012)
embryonic stage 7 -- 8
foregut anlage
(Fisher et al., 2012)
hindgut anlage
(Fisher et al., 2012)
posterior endoderm
(Fisher et al., 2012)
ventral ectoderm
(Fisher et al., 2012)
embryonic stage 9 -- 10
dorsal ectoderm
(Fisher et al., 2012)
foregut primordium
(Fisher et al., 2012)
inclusive hindgut primordium
(Fisher et al., 2012)
posterior endoderm
(Fisher et al., 2012)
trunk mesoderm
(Fisher et al., 2012)
embryonic stage 11 -- 12
anterior midgut primordium
(Fisher et al., 2012)
cardiogenic mesoderm
(Fisher et al., 2012)
dorsal epidermis primordium
(Fisher et al., 2012)
foregut primordium
(Fisher et al., 2012)
hindgut proper primordium
(Fisher et al., 2012)
labral sensory complex primordium
(Fisher et al., 2012)
posterior midgut primordium
(Fisher et al., 2012)
somatic muscle primordium

Comment: reported as muscle system primordium

(Fisher et al., 2012)
visceral muscle primordium

Comment: reported as muscle system primordium

(Fisher et al., 2012)
trunk mesoderm
(Fisher et al., 2012)
ventral epidermis primordium
(Fisher et al., 2012)
embryonic stage 13 -- 16
dorsal head epidermis
(Fisher et al., 2012)
embryonic dorsal epidermis
(Fisher et al., 2012)
embryonic epipharynx
(Fisher et al., 2012)
embryonic foregut
(Fisher et al., 2012)
embryonic ventral epidermis
(Fisher et al., 2012)
labral sensory complex
(Fisher et al., 2012)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
nucleus
inferred from direct assay
(Shim et al., 2001)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\rib in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 4-6
  • Stages(s) 9-10
  • Stages(s) 11-12
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 10 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 7 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of rib
Transgenic constructs containing regulatory region of rib
Deletions and Duplications ( 11 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal (with rib1)
lethal (with rib2)
lethal (with ribP16)
lethal (with ribP34)
lethal | recessive
lethal - all die before end of embryonic stage | recessive
lethal - all die before end of pupal stage, with Scer\GAL4pnr-MD237
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4tin.CΔ4
Other Phenotypes
Allele
cell migration defective | embryonic stage (with rib35.14)
cell migration defective | embryonic stage (with rib55.25)
cell polarity defective (with rib1)
cell polarity defective (with ribP7)
neuroanatomy defective | larval stage | recessive
some die during embryonic stage | recessive
some die during pupal stage, with Scer\GAL4pnr-MD237
Phenotype manifest in
Allele
abdominal 1 lateral pentascolopidial chordotonal organ lch5
abdominal 2 lateral pentascolopidial chordotonal organ lch5
abdominal 3 lateral pentascolopidial chordotonal organ lch5
abdominal 4 lateral pentascolopidial chordotonal organ lch5
abdominal 5 lateral pentascolopidial chordotonal organ lch5
abdominal 6 lateral pentascolopidial chordotonal organ lch5
abdominal 7 lateral pentascolopidial chordotonal organ lch5
denticle
denticle (with rib1)
denticle (with rib2)
denticle belt
denticle belt (with rib1)
denticle belt (with rib2)
dorsal hair
dorsal trunk primordium
dorsal trunk primordium (with rib1)
dorsal trunk primordium (with ribP7)
embryo | dorsal
embryo | dorsal closure stage
embryonic/first instar larval cuticle
embryonic/first instar larval cuticle (with rib1)
embryonic/first instar larval cuticle (with rib2)
embryonic/first instar larval cuticle | dorsal
embryonic/first instar larval cuticle | dorsal (with rib1)
embryonic/first instar larval cuticle | dorsal (with rib2)
embryonic/larval dorsal branch
embryonic/larval dorsal trunk
embryonic/larval ganglionic branch
embryonic/larval hindgut | embryonic stage
embryonic/larval lateral trunk
embryonic/larval midgut | embryonic stage
embryonic/larval salivary gland
embryonic/larval salivary gland | embryonic stage
embryonic/larval salivary gland common duct | embryonic stage
embryonic/larval salivary gland duct
embryonic/larval salivary gland duct | embryonic stage
embryonic/larval tracheal system
embryonic epidermis
embryonic epidermis | dorsal
embryonic head
embryonic midgut constriction
germline cell | embryonic stage (with rib1)
germline cell | embryonic stage (with rib35.14)
germline cell | embryonic stage (with rib55.25)
gonad | embryonic stage (with rib1)
gonad | embryonic stage (with rib6.24)
gonad | embryonic stage (with rib35.14)
gonad | embryonic stage (with rib55.25)
gonadal sheath proper primordium (with rib1)
gonadal sheath proper primordium (with rib35.14)
gonadal sheath proper primordium (with rib55.25)
gonadal sheath proper primordium | embryonic stage (with rib6.24)
gonadal sheath proper primordium | embryonic stage (with rib55.25)
head
Malpighian tubule
peripheral nervous system precursor cluster
presumptive embryonic/larval central nervous system
presumptive embryonic/larval peripheral nervous system
presumptive embryonic/larval tracheal system
presumptive embryonic/larval tracheal system (with Df(2R)rib-ex12)
presumptive embryonic salivary gland
presumptive embryonic salivary gland (with rib1)
presumptive embryonic salivary gland (with ribP7)
trachea
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v7.1)
Homo sapiens (Human) (2)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\ZBTB9
1 of 15
Yes
Yes
Hsap\ZBTB12
1 of 15
Yes
No
Model Organism Orthologs (via DIOPT v7.1)
Mus musculus (laboratory mouse) (0)
No records found.
Rattus norvegicus (Norway rat) (0)
No records found.
Xenopus tropicalis (Western clawed frog) (0)
No records found.
Danio rerio (Zebrafish) (1)
Drer\bcl6ab
1 of 15
Yes
No
Caenorhabditis elegans (Nematode, roundworm) (0)
No records found.
Arabidopsis thaliana (thale-cress) (0)
No records found.
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (0)
No records found.
Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG091904UC )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila melanogaster
fruit fly
Dmel\rib
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00005834
Drosophila simulans
Dsim\GD11439
Drosophila sechellia
Dsec\GM13162
Drosophila erecta
Dere\GG21956
Drosophila yakuba
Dyak\GE12030
Drosophila ananassae
Dana\GF11582
Drosophila pseudoobscura pseudoobscura
Dpse\GA20197
Drosophila persimilis
Dper\GL17640
Drosophila willistoni
Dwil\GK20672
Drosophila virilis
Dvir\GJ19776
Drosophila mojavensis
Dmoj\GI18921
Drosophila grimshawi
Dgri\GH23095
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091505XR )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17014462
Glossina morsitans
Tsetse fly
Gmor\GMOY009099
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_09338
Mayetiola destructor
Hessian fly
Mdes\Mdes007905
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL006690
Anopheles darlingi
American malaria mosquito
Adar\ADAC000442
Anopheles gambiae
Malaria mosquito
Agam\AGAP011902
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ010694
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W05X0 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA012231
Bombyx mori
Silkmoth
Bmor\BGIBMGA001210
Danaus plexippus
Monarch butterfly
Dple\DPOGS215980-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL008679
Heliconius melpomene
Postman butterfly
Hmel\HMEL004821
Apis florea
Little honeybee
Aflo\4916778884
Apis mellifera
Western honey bee
Amel\GB41167
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP14354
Bombus terrestris
Buff-tailed bumblebee
Bter\15204204
Linepithema humile
Argentine ant
Lhum\LH19143
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:001bbb
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG009116
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_07366
Tribolium castaneum
Red flour beetle
Tcas\GLEAN_07162
Pediculus humanus
Human body louse
Phum\PHUM088440
Pediculus humanus
Human body louse
Phum\PHUM088430
Rhodnius prolixus
Kissing bug
Rpro\RPRC007714
Cimex lectularius
Bed bug
Clec\CLEC007268
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI004381
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_14151
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( None identified )
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( None identified )
No non-Arthropod Metazoa orthologies identified
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v7.1)
Drosophila melanogaster (Fruit fly) (22)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
bab1
3 of 10
br
3 of 10
CG3726
3 of 10
CG8924
3 of 10
CG12236
3 of 10
CG32121
3 of 10
CG34376
3 of 10
chinmo
3 of 10
fru
3 of 10
lolal
3 of 10
lola
3 of 10
lov
3 of 10
mamo
3 of 10
psq
3 of 10
Trl
3 of 10
ttk
3 of 10
ab
2 of 10
bab2
2 of 10
BtbVII
2 of 10
CG6118
2 of 10
CG6765
1 of 10
mod(mdg4)
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    Summary of Genetic Interactions
    esyN Network Diagram
    esyN Network Key:
    Suppression
    Enhancement
    View in Interactions Browser
    Please look at the allele data for full details of the genetic interactions
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    rib
    suppressible
    crb
    (Kerman et al., 2008)
    rib
    enhanceable
    lola
    (Silva et al., 2016)
    rib
    suppressible
    Moe
    (Kerman et al., 2008)
    rib
    suppressible
    zip
    (Blake et al., 1999)
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    lola
    enhanceable
    rib
    (Silva et al., 2016)
    lolal
    enhanceable
    rib
    (Kerman et al., 2008)
    External Data
    Linkouts
    BioGRID - A database of protein and genetic interactions.
    DroID - A comprehensive database of gene and protein interactions.
    InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
    MIST (genetic) - An integrated Molecular Interaction Database
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Pathways
    Signaling Pathways (FlyBase)
    Metabolic Pathways
    External Data
    Linkouts
    Genomic Location and Detailed Mapping Data
    Chromosome (arm)
    2R
    Recombination map

    2-88

    Cytogenetic map
    56C6-56C6
    Sequence location
    2R:19,270,078..19,281,396 [+]
    FlyBase Computed Cytological Location
    Cytogenetic map
    Evidence for location
    56C6-56C6
    Limits computationally determined from genome sequence between P{PZ}ena02029&P{lacW}corak08713 and P{lacW}htsk06121
    Experimentally Determined Cytological Location
    Cytogenetic map
    Notes
    References
    Experimentally Determined Recombination Data
    Location

    2-88

    (FlyBase, 2016, Tearle and Nusslein-Volhard, 1987)

    2-94.1

    (Comeron et al., 2012)
    Left of (cM)
    Right of (cM)
    (Shim et al., 2001)
    Notes
    Stocks and Reagents
    Stocks (8)
    Genomic Clones (19)
     

    Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

    cDNA Clones (261)
     

    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

    cDNA clones, fully sequences
    BDGP DGC clones
    Other clones
    Drosophila Genomics Resource Center cDNA clones

    For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

    cDNA Clones, End Sequenced (ESTs)
    BDGP DGC clones
    Other clones
    RNAi and Array Information
    Linkouts
    DRSC - Results frm RNAi screens
    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
    Antibody Information
    Laboratory Generated Antibodies
     
    Commercially Available Antibodies
     
    Other Information
    Relationship to Other Genes
    Source for database identify of
    Source for database merge of

    Source for merge of: CG7230 rib

    (Bradley and Andrew, 2001)
    Additional comments
    Other Comments

    rib is required for specific tracheal branch migration.

    (Bradley and Andrew, 2001)

    Mutations in rib disrupt the coupling of movement of the cell bodies and apical and basal surfaces of the tracheal epithelium that is normally seen during tracheal system development; in rib mutants the basal surface continues to extend towards its normal targets, but movement and morphogenesis of the tracheal cell boies and apical surface is severely impaired.

    (Shim et al., 2001)

    rib is required for the proper shape of tubular epithelial tissues in Drosophila.

    (Jack and Myette, 1997)
    Origin and Etymology
    Discoverer
    Etymology
    Identification
    External Crossreferences and Linkouts ( 44 )
    Sequence Crossreferences
    NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
    GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
    GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
    RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
    UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
    Other crossreferences
    BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
    Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
    Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
    Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
    Flygut - An atlas of the Drosophila adult midgut
    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
    InterPro - A database of protein families, domains and functional sites
    KEGG Genes - Molecular building blocks of life in the genomic space.
    modMine - A data warehouse for the modENCODE project
    Linkouts
    BioGRID - A database of protein and genetic interactions.
    DPiM - Drosophila Protein interaction map
    DroID - A comprehensive database of gene and protein interactions.
    DRSC - Results frm RNAi screens
    FLIGHT - Cell culture data for RNAi and other high-throughput technologies
    FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
    FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
    FlyMine - An integrated database for Drosophila genomics
    Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
    InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
    MIST (genetic) - An integrated Molecular Interaction Database
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Synonyms and Secondary IDs (8)
    Datasets (0)
    Study focus (0)
    Experimental Role
    Project
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    References (102)