DLGR2, lgr2, BG:DS00180.13 , DLGR-2
Gene model reviewed during 5.52
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\rk using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\rk in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of glycoprotein-hormone-receptor-II CG8930 was sequence comparison ( date:000504 ).
The rk receptor and its signal Burs appear to be involved in intercellular communication within the border follicle cell cluster itself during border cell migration, as the Burs signal is only required in the border cells.
rk is necessary for the death and resorption of wing blade cells after eclosion.
Strong alleles have legs, especially metathoracic ones, flattened and bent. Femora and tibiae bowed in middle; first two tarsal joints shortened, bent and flattened; last three tarsal joints almost fused. Wings unexpanded, resembling those of pu. Posterior scutellar bristles erect and crossed. Viability may be reduced. Weak alleles do not show the leg phenotype, or they overlap wild type; may have partially expanded wings and normal posterior scutellar bristles. Even strong alleles more extreme when hemizygous with rk deficiencies.