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Gene Dmel\rod

General Information
Symbol	Dmel\rod	Species	D. melanogaster
Name	rough deal	Annotation symbol	CG1569
Feature type	protein_coding_gene	FlyBase ID	FBgn0003268
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map	3-105.1
Cytogenetic map	100C6-100C7	Sequence location	3R:27,406,394..27,413,861 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene rough deal is referred to in FlyBase by the symbol Dmel\rod (CG1569, FBgn0003268). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: protein localization to kinetochore; mitotic sister chromatid segregation. 20 alleles are reported. The phenotypes of these alleles are annotated with: eye; trichogen cell; mitotic anaphase; intersegmental nerve; nuclear chromosome; spermatocyte; meiotic cell cycle. It has one annotated transcript and one annotated polypeptide. Protein features are: RZZ complex, subunit KNTC1/ROD, C-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1632559_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of rod. Gene sequence location is 3R:27406394..27413861.
User Contributed Data
	Beta version, feedback welcome
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	rod: rough deal Mutants show mitotic abnormalities in larval neuroblasts; there is a high frequency of both aneuploid cells and abnormal anaphase figures, with lagging chromatids, anaphase bridges, and stretched chromatid arms. Abnormal chromosome behavior also occurs in the second meiotic anaphase in male meiosis, although motile sperm are produced. All surviving homozygous females and 90% of surviving homozygous males are sterile and have roughened eyes, sparse abdominal bristles, and notched wings.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 100C6-100C7   Limits computationally determined from genome sequence between P{EP}pygoEP1076 and P{PZ}ttk02667&P{lacW}ttkj6C7
Experimentally Determined Cytological Location
Cytogenetic map Notes References 100C5-100C5     (Aguliera, 1998.12.16) 100C-100D   (determined by in situ hybridisation)   (Karess and Glover, 1989)
Experimentally Determined Recombination Data
Location	3-105.1
Left of (cM)
Right of (cM)	ca
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\rod for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) rod-RA FBtr0085795  NM_057357   6653   2089
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein rod-PA   FBpp0085156   239.7   2089   6.07     NP_476705   AAF57162
Additional Polypeptide Data & Comments
Reported size (kDa)	2098 (aa); 200 (kD observed); 240 (kD predicted) (Scaerou et al., 1999)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • RZZ complex, subunit KNTC1/ROD, C-terminal (IPR019527)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF57162   AC009349   AF114152 AAD12541   AQ073988   CL705792   CO187517   CO189081   CO277027   CO277093   CO296799   CO309476   CO332627   CO343008   CZ483444   CZ483445   EC060228   EC069373   EC074623   EC090663   EC195089   EC217917   EC236413   EC243598   EC252170   EC257305   EL871534   EL871641   EL871893   FL502421   FL502473   FL502681   FL502823   FL502918   GR705692   GR705801
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9V9W7 O96695
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
western blot Stage Tissue/Position (including subcellular localization) Reference larval stage   embryonic/larval brain   (Scaerou et al., 1999) third instar larval stage   neuroblast of embryonic/larval brain   (Scaerou et al., 1999) spermatogenesis & adult stage   spermatocyte   (Scaerou et al., 1999)
Additional Descriptive Data
	A 200 kD rod protein is detected in western blots of extracts of Schneider L2 tissue culture cells and of larval brains. rod protein localizes in similar dynamic patterns in meiotic spermatocytes and in mitotic neuroblasts from third larval instar brains. The protein localizes to kinetochores at prometaphase, is found in kinetochores and kinetochore microtubule fibers at metaphase, and once again localizes to kinetochores at anaphase. (Scaerou et al., 1999)
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
cytoplasm inferred from direct assay (Buffin et al., 2005) kinetochore inferred from direct assay (Scaerou et al., 1999, Basto et al., 2004, Buffin et al., 2005, Scaerou et al., 2001, Griffis et al., 2007) kinetochore microtubule inferred from direct assay (Scaerou et al., 1999, Basto et al., 2004, Buffin et al., 2005, Scaerou et al., 2001) spindle inferred from direct assay (Griffis et al., 2007)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    121.35 Larval Midgut    13.5 Larval Hindgut    16.3 Larval Malpighian Tubules    15.4 Larval Fat Body    25.6 Larval Salivary Gland    9.8 Larval Trachea    38.625 Larval Carcass    23.325 Adult Head    11 Adult Eye    12.225 Adult Brain    11.6 Adult Thoracic-Abdominal Ganglion    15.1 Adult Crop    11.8 Adult Midgut    16.7 Adult Hindgut    13.9 Adult Malpighian Tubules    9.5 Adult Fat Body    16.2 Adult Salivary Gland    10.5 Adult Heart    11.675 Adult VirginFemale Spermatheca    9.7 Adult InseminatedFemale Spermatheca    10.4 Adult Ovary    196.6 Adult Testis    36.9 Adult Male Accessory Gland    5.1 Adult Carcass    14.6 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    121.35 Larval Midgut    13.5 Larval Hindgut    16.3 Larval Malpighian Tubules    15.4 Larval Fat Body    25.6 Larval Salivary Gland    9.8 Larval Trachea    38.625 Larval Carcass    23.325 Adult Head    11 Adult Eye    12.225 Adult Brain    11.6 Adult Thoracic-Abdominal Ganglion    15.1 Adult Crop    11.8 Adult Midgut    16.7 Adult Hindgut    13.9 Adult Malpighian Tubules    9.5 Adult Fat Body    16.2 Adult Salivary Gland    10.5 Adult Heart    11.675 Adult VirginFemale Spermatheca    9.7 Adult InseminatedFemale Spermatheca    10.4 Adult Ovary    196.6 Adult Testis    36.9 Adult Male Accessory Gland    5.1 Adult Carcass    14.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    121.35 Larval Midgut    13.5 Larval Hindgut    16.3 Larval Malpighian Tubules    15.4 Larval Fat Body    25.6 Larval Salivary Gland    9.8 Larval Trachea    38.625 Larval Carcass    23.325 Adult Head    11 Adult Eye    12.225 Adult Brain    11.6 Adult Thoracic-Abdominal Ganglion    15.1 Adult Crop    11.8 Adult Midgut    16.7 Adult Hindgut    13.9 Adult Malpighian Tubules    9.5 Adult Fat Body    16.2 Adult Salivary Gland    10.5 Adult Heart    11.675 Adult VirginFemale Spermatheca    9.7 Adult InseminatedFemale Spermatheca    10.4 Adult Ovary    196.6 Adult Testis    36.9 Adult Male Accessory Gland    5.1 Adult Carcass    14.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    121.35 Larval Midgut    13.5 Larval Hindgut    16.3 Larval Malpighian Tubules    15.4 Larval Fat Body    25.6 Larval Salivary Gland    9.8 Larval Trachea    38.625 Larval Carcass    23.325 Adult Head    11 Adult Eye    12.225 Adult Brain    11.6 Adult Thoracic-Abdominal Ganglion    15.1 Adult Crop    11.8 Adult Midgut    16.7 Adult Hindgut    13.9 Adult Malpighian Tubules    9.5 Adult Fat Body    16.2 Adult Salivary Gland    10.5 Adult Heart    11.675 Adult VirginFemale Spermatheca    9.7 Adult InseminatedFemale Spermatheca    10.4 Adult Ovary    196.6 Adult Testis    36.9 Adult Male Accessory Gland    5.1 Adult Carcass    14.6 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    121.35 Larval Midgut    13.5 Larval Hindgut    16.3 Larval Malpighian Tubules    15.4 Larval Fat Body    25.6 Larval Salivary Gland    9.8 Larval Trachea    38.625 Larval Carcass    23.325 Adult Head    11 Adult Eye    12.225 Adult Brain    11.6 Adult Thoracic-Abdominal Ganglion    15.1 Adult Crop    11.8 Adult Midgut    16.7 Adult Hindgut    13.9 Adult Malpighian Tubules    9.5 Adult Fat Body    16.2 Adult Salivary Gland    10.5 Adult Heart    11.675 Adult VirginFemale Spermatheca    9.7 Adult InseminatedFemale Spermatheca    10.4 Adult Ovary    196.6 Adult Testis    36.9 Adult Male Accessory Gland    5.1 Adult Carcass    14.6 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    121.35 Larval Midgut    13.5 Larval Hindgut    16.3 Larval Malpighian Tubules    15.4 Larval Fat Body    25.6 Larval Salivary Gland    9.8 Larval Trachea    38.625 Larval Carcass    23.325 Adult Head    11 Adult Eye    12.225 Adult Brain    11.6 Adult Thoracic-Abdominal Ganglion    15.1 Adult Crop    11.8 Adult Midgut    16.7 Adult Hindgut    13.9 Adult Malpighian Tubules    9.5 Adult Fat Body    16.2 Adult Salivary Gland    10.5 Adult Heart    11.675 Adult VirginFemale Spermatheca    9.7 Adult InseminatedFemale Spermatheca    10.4 Adult Ovary    196.6 Adult Testis    36.9 Adult Male Accessory Gland    5.1 Adult Carcass    14.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    121.35 Larval Midgut    13.5 Larval Hindgut    16.3 Larval Malpighian Tubules    15.4 Larval Fat Body    25.6 Larval Salivary Gland    9.8 Larval Trachea    38.625 Larval Carcass    23.325 Adult Head    11 Adult Eye    12.225 Adult Brain    11.6 Adult Thoracic-Abdominal Ganglion    15.1 Adult Crop    11.8 Adult Midgut    16.7 Adult Hindgut    13.9 Adult Malpighian Tubules    9.5 Adult Fat Body    16.2 Adult Salivary Gland    10.5 Adult Heart    11.675 Adult VirginFemale Spermatheca    9.7 Adult InseminatedFemale Spermatheca    10.4 Adult Ovary    196.6 Adult Testis    36.9 Adult Male Accessory Gland    5.1 Adult Carcass    14.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    121.35 Larval Midgut    13.5 Larval Hindgut    16.3 Larval Malpighian Tubules    15.4 Larval Fat Body    25.6 Larval Salivary Gland    9.8 Larval Trachea    38.625 Larval Carcass    23.325 Adult Head    11 Adult Eye    12.225 Adult Brain    11.6 Adult Thoracic-Abdominal Ganglion    15.1 Adult Crop    11.8 Adult Midgut    16.7 Adult Hindgut    13.9 Adult Malpighian Tubules    9.5 Adult Fat Body    16.2 Adult Salivary Gland    10.5 Adult Heart    11.675 Adult VirginFemale Spermatheca    9.7 Adult InseminatedFemale Spermatheca    10.4 Adult Ovary    196.6 Adult Testis    36.9 Adult Male Accessory Gland    5.1 Adult Carcass    14.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    11   NA  Eye    12.225   NA  Brain    11.6   121.35  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    15.1   NA  Crop    no informative data   13.5  Midgut    16.7   16.3  Hindgut    13.9   15.4  Malpighian Tubules    9.5   no informative data  Fat Body    16.2   9.8  Salivary Gland    no informative data   NA  Heart    11.675   38.625  Trachea    NA   NA  VirginFemale Spermatheca    9.7   NA  InseminatedFemale Spermatheca    10.4   NA  Ovary    196.6   NA  Testis    36.9   NA  Male Accessory Gland    5.1   23.325  Carcass    14.6 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    6 central nervous system, pupae P8    1 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    1 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    1 head, mated 4-day male    1 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    4 carcass, 1-day adult    0 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    23 ovary, mated 4-day female    16 testis, mated 4-day male    2 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    6 central nervous system, pupae P8    1 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    1 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    1 head, mated 4-day male    1 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    4 carcass, 1-day adult    0 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    23 ovary, mated 4-day female    16 testis, mated 4-day male    2 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    6 central nervous system, pupae P8    1 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    1 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    1 head, mated 4-day male    1 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    4 carcass, 1-day adult    0 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    23 ovary, mated 4-day female    16 testis, mated 4-day male    2 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    6 central nervous system, pupae P8    1 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    1 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    1 head, mated 4-day male    1 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    4 carcass, 1-day adult    0 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    23 ovary, mated 4-day female    16 testis, mated 4-day male    2 accessory gland, mated 4-day male    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    6 central nervous system, pupae P8    1 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    1 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    1 head, mated 4-day male    1 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    4 carcass, 1-day adult    0 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    23 ovary, mated 4-day female    16 testis, mated 4-day male    2 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    6 central nervous system, pupae P8    1 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    1 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    1 head, mated 4-day male    1 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    4 carcass, 1-day adult    0 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    23 ovary, mated 4-day female    16 testis, mated 4-day male    2 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    6 central nervous system, pupae P8    1 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    1 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    1 head, mated 4-day male    1 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    4 carcass, 1-day adult    0 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    23 ovary, mated 4-day female    16 testis, mated 4-day male    2 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    6 central nervous system, pupae P8    1 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    1 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    1 head, mated 4-day male    1 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    4 carcass, 1-day adult    0 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    23 ovary, mated 4-day female    16 testis, mated 4-day male    2 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    8 embryo 04-06hr    22 embryo 06-08hr    27 embryo 08-10hr    16 embryo 10-12hr    4 embryo 12-14hr    3 embryo 14-16hr    2 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    2 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    6 white prepupae new    5 white prepupae 12hr    10 white prepupae 24hr    8 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    2 adult male 30day    2 adult female 01day    7 adult female 05day    17 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (29) embryo 02-04hr    8 embryo 04-06hr    22 embryo 06-08hr  (27) embryo 08-10hr    16 embryo 10-12hr    4 embryo 12-14hr    3 embryo 14-16hr    2 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    2 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    6 white prepupae new    5 white prepupae 12hr    10 white prepupae 24hr    8 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    2 adult male 30day    2 adult female 01day    7 adult female 05day    17 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    8 embryo 04-06hr    22 embryo 06-08hr    27 embryo 08-10hr    16 embryo 10-12hr    4 embryo 12-14hr    3 embryo 14-16hr    2 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    2 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    6 white prepupae new    5 white prepupae 12hr    10 white prepupae 24hr    8 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    2 adult male 30day    2 adult female 01day    7 adult female 05day    17 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    8 embryo 04-06hr    22 embryo 06-08hr    27 embryo 08-10hr    16 embryo 10-12hr    4 embryo 12-14hr    3 embryo 14-16hr    2 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    2 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    6 white prepupae new    5 white prepupae 12hr    10 white prepupae 24hr    8 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    2 adult male 30day    2 adult female 01day    7 adult female 05day    17 adult female 30day    17 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    8 embryo 04-06hr    22 embryo 06-08hr    27 embryo 08-10hr    16 embryo 10-12hr    4 embryo 12-14hr    3 embryo 14-16hr    2 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    2 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    6 white prepupae new    5 white prepupae 12hr    10 white prepupae 24hr    8 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    2 adult male 30day    2 adult female 01day    7 adult female 05day    17 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  29 embryo 02-04hr    8 embryo 04-06hr    22 embryo 06-08hr  27 embryo 08-10hr    16 embryo 10-12hr    4 embryo 12-14hr    3 embryo 14-16hr    2 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    2 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    6 white prepupae new    5 white prepupae 12hr    10 white prepupae 24hr    8 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    2 adult male 30day    2 adult female 01day    7 adult female 05day    17 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    8 embryo 04-06hr    22 embryo 06-08hr    27 embryo 08-10hr    16 embryo 10-12hr    4 embryo 12-14hr    3 embryo 14-16hr    2 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    2 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    6 white prepupae new    5 white prepupae 12hr    10 white prepupae 24hr    8 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    2 adult male 30day    2 adult female 01day    7 adult female 05day    17 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    8 embryo 04-06hr    22 embryo 06-08hr    27 embryo 08-10hr    16 embryo 10-12hr    4 embryo 12-14hr    3 embryo 14-16hr    2 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    2 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    6 white prepupae new    5 white prepupae 12hr    10 white prepupae 24hr    8 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    2 adult male 30day    2 adult female 01day    7 adult female 05day    17 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    19 Schneider line 2 Sg4    11 embryonic 1182-4H    14 embryonic GM2    10 embryonic Kc167    9 embryonic S1    13 embryonic S3    13 leg disc CME L1    9 wing disc CME-W2    8 wing disc ML-DmD8    15 wing disc ML-DmD9    12 wing disc ML-DmD16-c3    12 wing disc ML-DmD21    6 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    12 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    8 ovary fGS/OSS    16 ovary OSC    12 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    19 Schneider line 2 Sg4    11 embryonic 1182-4H    14 embryonic GM2    10 embryonic Kc167    9 embryonic S1    13 embryonic S3    13 leg disc CME L1    9 wing disc CME-W2    8 wing disc ML-DmD8    15 wing disc ML-DmD9    12 wing disc ML-DmD16-c3    12 wing disc ML-DmD21    6 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    12 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    8 ovary fGS/OSS    16 ovary OSC    12 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    19 Schneider line 2 Sg4    11 embryonic 1182-4H    14 embryonic GM2    10 embryonic Kc167    9 embryonic S1    13 embryonic S3    13 leg disc CME L1    9 wing disc CME-W2    8 wing disc ML-DmD8    15 wing disc ML-DmD9    12 wing disc ML-DmD16-c3    12 wing disc ML-DmD21    6 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    12 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    8 ovary fGS/OSS    16 ovary OSC    12 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    19 Schneider line 2 Sg4    11 embryonic 1182-4H    14 embryonic GM2    10 embryonic Kc167    9 embryonic S1    13 embryonic S3    13 leg disc CME L1    9 wing disc CME-W2    8 wing disc ML-DmD8    15 wing disc ML-DmD9    12 wing disc ML-DmD16-c3    12 wing disc ML-DmD21    6 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    12 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    8 ovary fGS/OSS    16 ovary OSC    12 ovary OSS    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    19 Schneider line 2 Sg4    11 embryonic 1182-4H    14 embryonic GM2    10 embryonic Kc167    9 embryonic S1    13 embryonic S3    13 leg disc CME L1    9 wing disc CME-W2    8 wing disc ML-DmD8    15 wing disc ML-DmD9    12 wing disc ML-DmD16-c3    12 wing disc ML-DmD21    6 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    12 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    8 ovary fGS/OSS    16 ovary OSC    12 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    19 Schneider line 2 Sg4    11 embryonic 1182-4H    14 embryonic GM2    10 embryonic Kc167    9 embryonic S1    13 embryonic S3    13 leg disc CME L1    9 wing disc CME-W2    8 wing disc ML-DmD8    15 wing disc ML-DmD9    12 wing disc ML-DmD16-c3    12 wing disc ML-DmD21    6 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    12 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    8 ovary fGS/OSS    16 ovary OSC    12 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    19 Schneider line 2 Sg4    11 embryonic 1182-4H    14 embryonic GM2    10 embryonic Kc167    9 embryonic S1    13 embryonic S3    13 leg disc CME L1    9 wing disc CME-W2    8 wing disc ML-DmD8    15 wing disc ML-DmD9    12 wing disc ML-DmD16-c3    12 wing disc ML-DmD21    6 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    12 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    8 ovary fGS/OSS    16 ovary OSC    12 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    19 Schneider line 2 Sg4    11 embryonic 1182-4H    14 embryonic GM2    10 embryonic Kc167    9 embryonic S1    13 embryonic S3    13 leg disc CME L1    9 wing disc CME-W2    8 wing disc ML-DmD8    15 wing disc ML-DmD9    12 wing disc ML-DmD16-c3    12 wing disc ML-DmD21    6 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    12 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    8 ovary fGS/OSS    16 ovary OSC    12 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    14 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    8 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    8 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    14 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    8 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    8 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    14 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    8 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    8 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    14 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    8 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    8 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    14 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    8 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    8 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    14 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    8 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    8 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    14 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    8 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    8 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    14 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    8 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    8 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_06 mE1_20_mRNA_expression_cluster_06
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0003268 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1569-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | larval stage | recessive rodH4.8 lethal | recessive rodX-1 partially lethal - majority live rodX-2 viable rodEY04576 viable, with Scer\GAL4pnr-MD237 rodGD8768 viable | reduced rodX-3 rodX-4 Sterility Allele fertile rodEY04576 Other Phenotypes Allele mitotic cell cycle defective rodX-1 rodX-2 rodX-3 rodX-4 rodX-5 visible, with Scer\GAL4ey.PH rodEP3408 visible, with Scer\GAL4pnr-MD237 rodGD8768 wild-type rod+tC3L9 Phenotype manifest in Allele chromatin & mitotic anaphase rodH4.8 chromatin & mitotic telophase rodH4.8 eye, with Scer\GAL4ey.PH rodEP3408 intersegmental nerve, with Scer\GAL4elav-C155 rodEP3408 meiotic cell cycle rod1100 mitotic anaphase rodX-1 rodX-2 rodX-3 rodX-4 rodX-5 nuclear chromosome rodX-2 rodX-5 nuclear chromosome & mitotic anaphase rodH4.8 spermatocyte rod1100 trichogen cell, with Scer\GAL4pnr-MD237 rodGD8768
Classical Alleles ( 15 )
For All Classical Alleles Show
Allele of rod Class Mutagen Stocks Known lesion rodEY04576 P-element activity 1 -- rodf00967 piggyBac transposase 1 -- rodX-1 X ray 1 Yes rod1100 ethyl methanesulfonate 0 Yes rod29D PM hybrid dysgenesis 0 Yes rodEP3408 P-element activity 0 -- rodH4.8 PM hybrid dysgenesis 0 Yes rodpygo9 Delta2-3 0 Yes rodRP153 PM hybrid dysgenesis 0 Yes rodunspecified 0 -- rodX-2 X ray 0 -- rodX-3 X ray 0 -- rodX-4 X ray 0 -- rodX-5 X ray 0 Yes rodX-6 X ray 0 --
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of rod Class Mutagen Stocks Known lesion rod+tC3L9 in vitro construct - genomic fragment 1 Yes rodGD8768 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes rodNIG.1569R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes rodT:Avic\GFP-EGFP in vitro construct - coding region fusion 0 Yes rodT:Disc\RFP-mRFP in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)A113 (Schejter and Wieschaus, 1993) Df(3R)E(sina)9 (Wisotzkey et al., 1998) Df(3R)P4.1 (Scaerou et al., 1999)
Not disrupted in	Df(3R)E40 (Wisotzkey et al., 1998) Df(3R)Kpn-A (Wisotzkey et al., 1998)
Duplicated in	Dp(3;1)48 (Schejter and Wieschaus, 1993)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD8768} NA P{NIG.1569R} NA characterization construct P{rod.RFP} NA P{rod+tC3L9} NA P{rod-GFP.B} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}rodEP3408 NA P{EPgy2}rodEY04576 NA miscellaneous insertions ?{}rod29D NA ?{}rodRP153 NA Doc{}rodH4.8 NA PBac{WH}rodf00967 NA
Gene Ontology: Function, Process & Cellular Component ( 8 unique terms )
Terms Based on Experimental Evidence ( 6 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
mitotic sister chromatid segregation inferred from mutant phenotype (Scaerou et al., 2001) protein localization to kinetochore inferred from mutant phenotype (Dzhindzhev et al., 2005)
Cellular Component
CV term Evidence References
cytoplasm inferred from direct assay (Buffin et al., 2005) kinetochore inferred from direct assay (Scaerou et al., 1999, Basto et al., 2004, Buffin et al., 2005, Scaerou et al., 2001, Griffis et al., 2007) kinetochore microtubule inferred from direct assay (Scaerou et al., 1999, Basto et al., 2004, Buffin et al., 2005, Scaerou et al., 2001) spindle inferred from direct assay (Griffis et al., 2007)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
mitotic spindle assembly checkpoint non-traceable author statement (Gonzalez and Bornens, 2000) traceable author statement (Lee and Orr-Weaver, 2003)
Cellular Component
CV term Evidence References
condensed chromosome outer kinetochore non-traceable author statement (Blower and Karpen, 2001) kinetochore microtubule non-traceable author statement (Gonzalez and Bornens, 2000)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions rod allele Gene References rodX-5 asp (Basto et al., 2000) unspecified L (Singh et al., 2005)
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0003268
Orthologs
OrthoDB Orthologs (41) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6FTWJV Dipteran inclusive ortholog search EOG605S80 Insect inclusive ortholog search EOG6893H0 Arthropod inclusive ortholog search EOG6SF7ND Metazoa inclusive ortholog search EOG6P8TBM
Orthologs in Drosophila Species (EOG6FTWJV)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\rod     Drosophila simulans   Dsim\GD21586     Drosophila simulans   Dsim\GD21584     Drosophila sechellia   Dsec\GM16431 Y   Drosophila erecta   Dere\GG11814 Y   Drosophila yakuba   Dyak\GE10947 Y   Drosophila ananassae   Dana\GF22970 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA13892 Y   Drosophila persimilis   Dper\GL23634 Y   Drosophila willistoni   Dwil\GK11720 Y   Drosophila virilis   Dvir\GJ23087 Y   Drosophila mojavensis   Dmoj\GI23397 Y   Drosophila grimshawi   Dgri\GH18637 Y
Orthologs in non-Drosophila Dipterans (EOG605S80)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL008377   Anopheles gambiae Malaria mosquito  Agam\AGAP012160   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ010074
Orthologs in non-Dipteran Insects (EOG6893H0)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB55917   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH15882   Atta cephalotes Leafcutter ant  Acep\ACEP10982   Camponotus floridanus Florida carpenter ant  Cflo\CFLO20092   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL14089   Linepithema humile Argentine ant  Lhum\LH17842   Pogonomyrmex barbatus Red harvester ant  Pbar\PB11712   Solenopsis invicta Red fire ant  Sinv\SINV14852   Acyrthosiphon pisum Pea aphid  Apim\ACYPI29158   Bombyx mori Silkmoth  Bmor\BGIBMGA002655   Tribolium castaneum Red flour beetle  Tcas\TC005217
Orthologs in non-Insect Arthropods (EOG6SF7ND)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\Olfml2b   Ixodes scapularis Deer tick  Isca\ISCW004579
Orthologs in non-Arthropod Metazoa (EOG6P8TBM)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\rod-1   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_009113gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016435gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_011941gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_008168gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_025237gn   Danio rerio Zebrafish  Drer\im:7138629   Xenopus tropicalis Western clawed frog  Xtro\kntc1   Gallus gallus Domestic chicken  Ggal\KNTC1   Mus musculus House mouse  Mmus\Kntc1   Rattus norvegicus Norway rat  Rnor\Kntc1   Homo sapiens Human  Hsap\KNTC1
Human Orthologs (1)
Gene OMIM HGNC Hsap\KNTC1
AAA Orthologs (10) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila sechellia Dsec\GM16431 Drosophila erecta Dere\GG11814 Drosophila yakuba Dyak\GE10947 Drosophila ananassae Dana\GF22970 Drosophila pseudoobscura pseudoobscura Dpse\GA13892 Drosophila persimilis Dper\GL23634 Drosophila willistoni Dwil\GK11720 Drosophila virilis Dvir\GJ23087 Drosophila mojavensis Dmoj\GI23397 Drosophila grimshawi Dgri\GH18637
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	19842 y1 w67c23; P{EPgy2}rodEY04576 29721 w*; P{rod+tC3L9}2; rodX-1/T(2;3)TSTL14, SM5: TM6B, Tb1
Harvard	- PBac{WH}rodf00967
VDRC	v19152 w1118; P{GD8768}v19152
Genomic Clones ( 2 )
	BACR10O09 BACR16C04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 22 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	1389 1630 63840 83357 214277.30 214545.30 277215 CK01.33D.C8 CK01.53B.C12 DMG4-chr3R.46.023.pred.a EK030131 EK042944 EK122663 EK122933 EK215201 EK217745 EK304110 EP15924 IP03619 IP03719 IP03919 MB6-CG1569-RA
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0003268 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43719
Antibody Information
	polyclonal (Scaerou et al., 1999)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: rod CG1569 (Zhao, 1999.11)
Source for database merge of	Source for merge of: rod EP3408 (FlyBase, 1996-)
Additional comments	FlyBase curator comment: "EP3408" overexpression phenotype stated to be due to its effect on pygo but orientation of the P{EP} element suggests otherwise. (Singh et al., 2005) Source for merge of rod EP3408 was that EP3408 insertion is within rod (and in the right orientation) (date:040519). (FlyBase, 1996-)
Other Comments
	dsRNA has been synthesised against this gene and transfected into S2 cells. (Griffis et al., 2007) dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003) Mutations in rod result in mitotic segregational failure due to delayed or incomplete release of sister chromatids. (Karess et al., 1990)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_057357 RefSeq (Proteins) • NP_476705 DDBJ / EMBL / GenBank • AAD12541 AAF57162 AC009349 AF114152 AQ073988 CL705792 CZ483444 CZ483445 Entrez Gene - A searchable database of RefSeq genes. • 43719 UniProtKB/TrEMBL • O96695 Q9V9W7
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • RZZ complex, subunit KNTC1/ROD, C-terminal (IPR019527)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0003268 DRSC - Results from RNAi screens. • FBgn0003268 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0003268 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1569-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0003268 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43719 modMine - Data generated by the modENCODE project. • FBgn0003268
Synonyms & Secondary IDs ( 10 )
Reported As
Symbol Synonym	CG1569 (Buffin, 2005, Buffin et al., 2005, Pile et al., 2003, Przewloka et al., 2007, Howell et al., 2012) EP3408 (Singh et al., 2005, ) pNB20A (Scaerou et al., 1999) ROD (Blower et al., 2006, Williams et al., 2003, Erhardt et al., 2005, Parry et al., 2003, Olszak et al., 2011, Torras-Llort et al., 2010, Heun et al., 2006, Godinho and Tavares, 2008) rod (Karess, 2005, Siller et al., 2005, Somma et al., 2008, Siller and Doe, 2008, Buffin et al., 2007, Castellanos et al., 2008, Williams et al., 2007, Peng and Karpen, 2009, Wainman et al., 2009, Blower et al., 2006, Cabernard et al., 2010, Mottier-Pavie et al., 2011, Japanese National Institute of Genetics, 2012.5.21, Kalajdzic et al., 2012) Rod (Garcia et al., 2007, Griffis et al., 2007, Przewloka et al., 2007, Finan et al., 2011, Dzhindzhev et al., 2005, Wen et al., 2008, Pandey et al., 2007, Lince-Faria et al., 2009, Reis et al., 2009, Rahmani et al., 2009) unnamed (Kraut et al., 2001)
Name Synonym	rough deal (Aguliera, 1998.12.16, Parker et al., 2008, Castellanos et al., 2008, Howell et al., 2012) Rough deal (Dzhindzhev et al., 2005) Rough Deal (Emre et al., 2011)
Secondary FlyBase IDs
	FBgn0044458
References ( 94 )
Generate a list of	All references relating to this gene ( 94 )
List References by type	Research paper  ( 52 ) Supplementary material  ( 7 ) Review  ( 13 ) Personal communication to FlyBase  ( 3 ) Abstract  ( 11 ) FlyBase analysis  ( 2 ) DNA/RNA sequence record  ( 1 ) Conference report  ( 2 ) Stock list  ( 1 ) Curated genome annotation  ( 1 ) Book  ( 1 )
Recent research papers ( 7 )
	Dekanty et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(50): 20549--20554 Aneuploidy-induced delaminating cells drive tumorigenesis in Drosophila epithelia. [FBrf0220285] Howell et al., 2012, Immunogenetics 64(2): 155--161 A directed miniscreen for genes involved in the Drosophila anti-parasitoid immune response. [FBrf0217123] Kalajdzic et al., 2012, PLoS ONE 7(6): e40296 Use of mutagenesis, genetic mapping and next generation transcriptomics to investigate insecticide resistance mechanisms. [FBrf0218826] Emre et al., 2011, J. Cell Sci. 124(10): 1664--1671 A mitotic role for Mad1 beyond the spindle checkpoint. [FBrf0213557] Finan et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(14): 5566--5571 From the Cover: Proteomics approach to study the functions of Drosophila myosin VI through identification of multiple cargo-binding proteins. [FBrf0213355] Mottier-Pavie et al., 2011, J. Cell Sci. 124(5): 706--717 Phenotypic analysis of misato function reveals roles of noncentrosomal microtubules in Drosophila spindle formation. [FBrf0212996] Olszak et al., 2011, Nat. Cell Biol. 13(7): 799--808 Heterochromatin boundaries are hotspots for de novo kinetochore formation. [FBrf0214065] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...