FlyBase Gene Report: Dmel\rod

General Information

Symbol

Dmel\rod

Species

D. melanogaster

Name

rough deal

Annotation Symbol

CG1569

Feature Type

protein_coding_gene

FlyBase ID

FBgn0003268

Gene Model Status

Stock Availability

3 publicly available

Gene Snapshot

rough deal (rod) encodes the major subunit of the Rod-Zw10-Zwilch (RZZ) complex. RZZ is an essential component of the outer kinetochore during mitosis. RZZ helps monitor and correct kinetochore-microtubule attachments during prometaphase, and consequently it regulates mitotic progression. [Date last reviewed: 2019-03-14]

Other Summaries

Alliance
Auto summary
Gene Group
Red Book
Interactive Fly

Also Known As

EP3408

Key Links

Genomic Location

Cytogenetic map

Sequence location

3R:31,580,951..31,588,244 [+]

Recombination map

3-102

RefSeq locus

NT_033777 REGION:31580951..31588244

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (16 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

enables protein binding

inferred from physical interaction with FLYBASE:Zw10; FB:FBgn0004643, FLYBASE:Zwilch; FB:FBgn0061476

(Williams et al., 2003)

enables small GTPase binding

inferred from physical interaction with FLYBASE:Rab18; FB:FBgn0015794

(Gillingham et al., 2014)

Terms Based on Predictions or Assertions (0 terms)

Biological Process (6 terms)

Terms Based on Experimental Evidence (6 terms)

CV Term

Evidence

References

involved_in Golgi organization

inferred from mutant phenotype

(Wainman et al., 2012)

involved_in mitotic sister chromatid segregation

inferred from mutant phenotype

(Scaerou et al., 2001)

involved_in mitotic spindle assembly checkpoint

inferred from mutant phenotype

(Basto et al., 2000)

involved_in protein localization to kinetochore

inferred from mutant phenotype

(Dzhindzhev et al., 2005)

involved_in regulation of chromosome separation

inferred from mutant phenotype

(Clemente-Ruiz et al., 2016)

involved_in regulation of mitotic metaphase/anaphase transition

inferred from mutant phenotype

(Défachelles et al., 2015)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (8 terms)

Terms Based on Experimental Evidence (8 terms)

CV Term

Evidence

References

located_in acroblast

inferred from direct assay

(Wainman et al., 2012)

located_in cytoplasm

inferred from direct assay

(Buffin et al., 2005)

located_in Golgi stack

inferred from direct assay

(Wainman et al., 2012)

located_in kinetochore microtubule

inferred from direct assay

(Wainman et al., 2012, Buffin et al., 2005, Basto et al., 2004, Scaerou et al., 2001, Scaerou et al., 1999)

located_in kinetochore

inferred from direct assay

(Wainman et al., 2012, Griffis et al., 2007, Buffin et al., 2005, Basto et al., 2004, Scaerou et al., 2001, Scaerou et al., 1999)

part_of RZZ complex

inferred from direct assay

(Williams et al., 2003)

inferred from physical interaction with FLYBASE:Zw10; FB:FBgn0004643, FLYBASE:Zwilch; FB:FBgn0061476

(Défachelles et al., 2015)

located_in spindle midzone

inferred from direct assay

(Wainman et al., 2012)

located_in spindle

inferred from direct assay

(Griffis et al., 2007)

Terms Based on Predictions or Assertions (0 terms)

Gene Group (FlyBase)

Protein Family (UniProt)

-

Protein Signatures (InterPro)

RZZ complex, subunit KNTC1/ROD, C-terminal

Summaries

Gene Group (FlyBase)

RZZ COMPLEX -: The RZZ (Rod, Zwilch and Zw10) complex is a kinetochore component that plays an essential role in spindle assembly checkpoint, blocking the metaphase-to-anaphase transition until all chromosomes properly aligned in a metaphase plate. In mammalian cells, the RZZ complex has a fourth component, Zwint-1. (Adapted from FBrf0219791).

Phenotypic Description (Red Book; Lindsley and Zimm 1992)

rod: rough deal

Mutants show mitotic abnormalities in larval neuroblasts; there is a high frequency of both aneuploid cells and abnormal anaphase figures, with lagging chromatids, anaphase bridges, and stretched chromatid arms. Abnormal chromosome behavior also occurs in the second meiotic anaphase in male meiosis, although motile sperm are produced. All surviving homozygous females and 90% of surviving homozygous males are sterile and have roughened eyes, sparse abdominal bristles, and notched wings.

Gene Model and Products

Number of Transcripts

1

Number of Unique Polypeptides

1

Please see the JBrowse view of Dmel\rod for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.53

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.55

Sequence Ontology: Class of Gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

FBtr0085795

6479

2089

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

FBpp0085156

239.7

2089

6.07

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

2098 (aa); 200 (kD observed); 240 (kD predicted)

(Scaerou et al., 1999)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

RZZ complex, subunit KNTC1/ROD, C-terminal

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\rod using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

rod_1

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

western blot

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

neuroblast of embryonic/larval brain

(Scaerou et al., 1999)

spermatogenesis & adult stage

(Scaerou et al., 1999)

embryonic/larval brain

(Scaerou et al., 1999)

Additional Descriptive Data

A 200 kD rod protein is detected in western blots of extracts of Schneider L2 tissue culture cells and of larval brains. rod protein localizes in similar dynamic patterns in meiotic spermatocytes and in mitotic neuroblasts from third larval instar brains. The protein localizes to kinetochores at prometaphase, is found in kinetochores and kinetochore microtubule fibers at metaphase, and once again localizes to kinetochores at anaphase.

(Scaerou et al., 1999)

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in acroblast

inferred from direct assay

(Wainman et al., 2012)

located_in cytoplasm

inferred from direct assay

(Buffin et al., 2005)

located_in Golgi stack

inferred from direct assay

(Wainman et al., 2012)

located_in kinetochore microtubule

inferred from direct assay

(Wainman et al., 2012, Buffin et al., 2005, Basto et al., 2004, Scaerou et al., 2001, Scaerou et al., 1999)

located_in kinetochore

inferred from direct assay

(Wainman et al., 2012, Griffis et al., 2007, Buffin et al., 2005, Basto et al., 2004, Scaerou et al., 2001, Scaerou et al., 1999)

part_of RZZ complex

inferred from direct assay

(Williams et al., 2003)

inferred from physical interaction with FLYBASE:Zw10; FB:FBgn0004643, FLYBASE:Zwilch; FB:FBgn0061476

(Défachelles et al., 2015)

located_in spindle midzone

inferred from direct assay

(Wainman et al., 2012)

located_in spindle

inferred from direct assay

(Griffis et al., 2007)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\rod in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\rod

View exonic expression by tissue for Dmel\rod

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0003268

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG1569-RA

Flygut - An atlas of the Drosophila adult midgut

FBgn0003268

Images

Image Based Resources

Alleles, Insertions, and Transgenic Constructs

Classical and Insertion Alleles ( 17 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 6 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of rod

Transgenic constructs containing regulatory region of rod

Deletions and Duplications ( 6 )

Disrupted in

(Schejter and Wieschaus, 1993)

(Wisotzkey et al., 1998)

(Scaerou et al., 1999)

Not disrupted in

(Wisotzkey et al., 1998)

(Wisotzkey et al., 1998)

Duplicated in

(Schejter and Wieschaus, 1993)

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal | recessive

rod^X-1

lethal - all die before end of embryonic stage | maternal effect

rod^Z3

lethal - all die before end of larval stage | recessive

rod^H4.8

partially lethal

partially lethal - majority live

rod^X-2

rod^EY04576

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

rod^GD8768

viable, with Scer\GAL4^Mef2.PR

rod^GD8768

viable, with Scer\GAL4^pnr-MD237

rod^GD8768

viable, with Scer\GAL4^tin.CΔ4

rod^GD8768

Sterility

Allele

rod^EY04576

Other Phenotypes

Allele

mitotic cell cycle defective

mitotic cell cycle defective | embryonic stage 4 | maternal effect | drug conditional

rod^Z3

mitotic cell cycle defective | maternal effect

rod^Z3

neuroanatomy defective | dominant | third instar larval stage

rod^Z3

neuroanatomy defective | third instar larval stage

neuroanatomy defective | third instar larval stage | drug conditional

rod^unspecified

some die during larval stage | recessive

rod^H4.8

visible, with Scer\GAL4^ey.PH

rod^EP3408

visible, with Scer\GAL4^pnr-MD237

rod^GD8768

rod^+tC3L9

Phenotype manifest in

Allele

rod¹¹⁰⁰

chromatin & mitotic anaphase

rod^H4.8

chromatin & mitotic telophase

rod^H4.8

embryonic/larval brain | third instar larval stage

rod^Z3

embryonic/larval brain | third instar larval stage | drug conditional

rod^unspecified

eye, with Scer\GAL4^ey.PH

rod^EP3408

rod¹¹⁰⁰

intersegmental nerve, with Scer\GAL4^elav-C155

rod^EP3408

kinetochore | third instar larval stage

larval neuroblast | third instar larval stage

meiotic cell cycle

rod¹¹⁰⁰

mitotic anaphase

rod^X-1

nuclear chromosome

nuclear chromosome & mitotic anaphase

rod^H4.8

nuclear chromosome | embryonic stage

rod^Z3

nucleus | embryonic stage

rod^Z3

polar body nucleus | embryonic stage

rod^Z3

polar body nucleus | embryonic stage 4 | drug conditional

rod^Z3

rod¹¹⁰⁰

trichogen cell, with Scer\GAL4^pnr-MD237

rod^GD8768

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

12 of 15

Yes

Yes

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

11 of 15

Yes

Yes

Rattus norvegicus (Norway rat) (2)

9 of 13

Yes

Yes

Rnor\LOC103693647

2 of 13

No

Yes

Xenopus tropicalis (Western clawed frog) (1)

7 of 12

Yes

Yes

Danio rerio (Zebrafish) (1)

8 of 15

Yes

Yes

Caenorhabditis elegans (Nematode, roundworm) (1)

8 of 15

Yes

Yes

Arabidopsis thaliana (thale-cress) (0)

No records found.

Saccharomyces cerevisiae (Brewer's yeast) (0)

No records found.

Schizosaccharomyces pombe (Fission yeast) (0)

No records found.

Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG0919007I )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila suzukii

Spotted wing Drosophila

Dsuz\DS10_00007387

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Drosophila persimilis

Drosophila willistoni

Drosophila virilis

Drosophila mojavensis

Drosophila grimshawi

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915004G )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Glossina morsitans

Tsetse fly

Gmor\GMOY011623

Mayetiola destructor

Hessian fly

Mdes\Mdes014456

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL008377

Anopheles darlingi

American malaria mosquito

Adar\ADAC005111

Anopheles gambiae

Malaria mosquito

Agam\AGAP012160

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ010074

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W003I )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA002655

Danaus plexippus

Monarch butterfly

Dple\DPOGS201748-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL006706

Apis florea

Little honeybee

Aflo\3853530644

Apis mellifera

Western honey bee

Bombus impatiens

Common eastern bumble bee

Bombus terrestris

Buff-tailed bumblebee

Linepithema humile

Argentine ant

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:0011f5

Tribolium castaneum

Red flour beetle

Rhodnius prolixus

Kissing bug

Rpro\RPRC006821

Rhodnius prolixus

Kissing bug

Rpro\RPRC004025

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI44608

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI29158

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_12433

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X010C )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Ixodes scapularis

Black-legged tick

Isca\ISCW004579

Stegodyphus mimosarum

African social velvet spider

Smim\KFM65632.1

Stegodyphus mimosarum

African social velvet spider

Smim\KFM65628.1

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_304960

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G01K5 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_009113gn

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_025237gn

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Kntc1_1

Strongylocentrotus purpuratus

Purple sea urchin

Strongylocentrotus purpuratus

Purple sea urchin

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000020157

Gallus gallus

Domestic chicken

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (0)

No records found.

Human Disease Associations

FlyBase Human Disease Model Reports

cancer, models of chromosomal instability

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

KNTC1; kinetochore associated 1

12 of 15

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

rod - DCTN1-p150

anti tag coimmunoprecipitation, western blot

(Basto et al., 2004)

rod - DCTN2-p50

anti tag coimmunoprecipitation, western blot

(Basto et al., 2004)

anti tag coimmunoprecipitation, western blot

(Basto et al., 2004)

anti tag coimmunoprecipitation, peptide massfingerprinting, western blot

(Défachelles et al., 2015)

anti tag coimmunoprecipitation, peptide massfingerprinting

(Przewloka et al., 2007)

anti tag coimmunoprecipitation, peptide massfingerprinting

(Przewloka et al., 2007)

pull down, peptide massfingerprinting, anti tag western blot

(Gillingham et al., 2014, Gillingham et al., 2014)

anti tag coimmunoprecipitation, peptide massfingerprinting, anti bait coimmunoprecipitation, western blot, molecular sieving

(Défachelles et al., 2015, D'Avino et al., 2009, Chen et al., 2007, Williams et al., 2003, Scaerou et al., 2001)

anti bait coimmunoprecipitation, peptide massfingerprinting, western blot

(Défachelles et al., 2015, Williams et al., 2003)

anti tag coimmunoprecipitation, peptide massfingerprinting

(Liu et al., 2015)

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

suppressible

(Défachelles et al., 2015)

suppressible

(Défachelles et al., 2015)

suppressible

(Muzzopappa et al., 2017)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

suppressible

(Basto et al., 2000)

enhanceable

(Singh et al., 2005)

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0003268

MIST (protein-protein) - An integrated Molecular Interaction Database

rod

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

Genomic Location and Detailed Mapping Data

Chromosome (arm)

3R

Recombination map

3-102

Cytogenetic map

Sequence location

3R:31,580,951..31,588,244 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

100C6-100C7

Limits computationally determined from genome sequence between P{EP}pygo^EP1076 and P{PZ}ttk⁰²⁶⁶⁷&P{lacW}ttk^j6C7

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

100C5-100C5

(Aguliera, 1998.12.16)

100C-100D

(determined by in situ hybridisation)

(Karess and Glover, 1989)

Experimentally Determined Recombination Data

Location

3-102

(FlyBase, 2016)

3-99.1

(Comeron et al., 2012)

3-105.1

Left of (cM)

Right of (cM)

ca

Notes

Stocks and Reagents

Stocks (3)

19842

y¹ w^67c23; P{EPgy2}rod^EY04576

29721

w^*; P{rod^+tC3L9}2/CyO; rod^X-1/TM6B, Tb¹

v19152

w¹¹¹⁸; P{GD8768}v19152

Genomic Clones (20)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (16)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0003268

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

43719

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Scaerou et al., 1999)

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for identity of: rod CG1569

(Zhao, 1999.11)

Source for database merge of

Source for merge of: rod EP3408

(FlyBase, 1996-)

Additional comments

FlyBase curator comment: "EP3408" overexpression phenotype stated to be due to its effect on pygo but orientation of the P{EP} element suggests otherwise.

(Singh et al., 2005)

Source for merge of rod EP3408 was that EP3408 insertion is within rod (and in the right orientation) ( date:040519 ).

(FlyBase, 1996-)

Other Comments

dsRNA has been synthesised against this gene and transfected into S2 cells.

(Griffis et al., 2007)

dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R⁺ cell morphology.

(Kiger et al., 2003)

Mutations in rod result in mitotic segregational failure due to delayed or incomplete release of sister chromatids.

(Karess et al., 1990)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 27 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

43719

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

rod_1

Flygut - An atlas of the Drosophila adult midgut

FBgn0003268

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

43719

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC034281

InterPro - A database of protein families, domains and functional sites

RZZ complex, subunit KNTC1/ROD, C-terminal

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG1569

modMine - A data warehouse for the modENCODE project

FBgn0003268

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0003268

DRSC - Results frm RNAi screens

FBgn0003268

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0003268

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG1569-RA

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0003268

FlyMine - An integrated database for Drosophila genomics

FBgn0003268

MIST (protein-protein) - An integrated Molecular Interaction Database

rod

Synonyms and Secondary IDs (11)

Reported As

Symbol Synonym

CG1569

(Çiçek et al., 2016, Howell et al., 2012, Przewloka et al., 2007, Buffin, 2005, Buffin et al., 2005, Pile et al., 2003)

EP3408

(Singh et al., 2005)

ROD

(Radford et al., 2015, Olszak et al., 2011, Torras-Llort et al., 2010, Godinho and Tavares, 2008, Blower et al., 2006, Heun et al., 2006, Erhardt et al., 2005, Parry et al., 2003, Williams et al., 2003)

Rod1

(Rosa-Ferreira et al., 2018)

pNB20A

(Scaerou et al., 1999)

Name Synonyms

Rough Deal

(Emre et al., 2011)

Rough deal

(Dzhindzhev et al., 2005)

rough deal

(Défachelles et al., 2015, Howell et al., 2012, Castellanos et al., 2008, Parker et al., 2008, Aguliera, 1998.12.16)

roughdeal

(Kuang et al., 2014)

Secondary FlyBase IDs

FBgn0044458

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

References (130)