Gene model reviewed during 5.43
Gene model reviewed during 5.44
Gene model reviewed during 5.48
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Sgs1 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Sgs1 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Sgs1 encodes the most slowly migrating of the salivary-gland glue proteins. One of a group of seven genes encoding proteins that are components of the secretion produced by the larval salivary glands during the third instar for the purpose of attaching the larva to the substrate preparative to pupariation.
Cessation of Sgs1 transcription and puff regression are ecdysterone-dependent.
Initiation of transcription of Sgs1, but not of intermolt-puff formation seems to depend on the presence of suitable levels of ecdysterone in early third instar larvae.
Synthesis of the glue proteins begins about 106 h after egg deposition and ceases abruptly within a few minutes after the glue is released 14 h later.