slg, sluggish, proline dehydrogenase
3.6, 2.5 (northern blot)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\slgA using the Feature Mapper tool.
Proline-oxidase activity was found in mitochondrial preparations.
GBrowse - Visual display of RNA-Seq signalsView Dmel\slgA in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: slgA CG1417
Complements sol (Miklos, Kelly, Coombe, Leeds and Lefevre, 1987). Also complements PC16, another phototaxis/geotaxis-defective mutation in the region, isolated in laboratory of S. Benzer and studied by Markow and Merriam (1977).
The slgA gene localised to a 14.7kb region at the base of the X chromosome and encodes proline oxidase.
Neither toxicity nor behavioural anomaly are detected upon application of proline analogues, 4-methylene L-proline and both isomers of 5-ethynyl proline.
Eichenberger and Benzer.