su(wa), EG:BACR7A4.10 , su(w)
Gene model reviewed during 5.48
Low-frequency RNA-Seq exon junction(s) not annotated.
Possible mutation in sequenced strain: 412 transposon in first intron may be spliced out with the use of conserved splice junctions that are present at the site of insertion, or may cause a mutation in this strain.
Gene model reviewed during 5.55
Gene model reviewed during 6.01
5.2, 4.4, 3.5 (northern blot)
1042, 964 (aa)
RS domain directs localization of proteins to the speckled subnuclear compartment and the purpose of this localization is to allow colocalization and co-concentration of components of the splicing and splicing regulatory machinery to permit relatively high rates and/or efficiencies of reaction and interaction.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\su(wa) using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\su(wa) in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Duplicate transcripts identified and eliminated during the migration of annotations from the release 5 genome assembly to the release 6 assembly.
su(wa) has the effect of a two fold increase in the mutant hh gene product at 25oC, and less of an effect at 18oC. This effect on hh mutations is comparable in magnitude to its effect on the splicing of the w gene in wa mutant flies.
Expression of su(wa) is controlled at the level of splicing, this post-transcriptional regulation constitutes autoregulation.
Enhances wa60a5 and wM. Seems to act on wa by promoting transcription through the copia element that is inserted into the second intron in the same orientation as that of w; the level of a read-through transcript is elevated in su(wa) wa compared to wa. su(wa) is without effect on the phenotype of whd81b11, which has copia inserted at another position and in the opposite direction.