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Gene Dmel\sws

General Information
Symbol	Dmel\sws	Species	D. melanogaster
Name	swiss cheese	Annotation symbol	CG2212
Feature type	protein_coding_gene	FlyBase ID	FBgn0003656
Gene Model Status	Current	Stock availability	10 publicly available
Also Known As	olfE
Genomic Location
Chromosome (arm)	X	Recombination map	1-22
Cytogenetic map	7D1-7D1	Sequence location	X:7,850,853..7,862,269 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene swiss cheese is referred to in FlyBase by the symbol Dmel\sws (CG2212, FBgn0003656). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: lysophospholipase activity. There is experimental evidence that it is involved in the biological process: membrane lipid metabolic process; phosphatidylcholine metabolic process; cellular membrane organization; sensory perception of smell; neuron apoptosis. 20 alleles are reported. The phenotypes of these alleles are annotated with: cortex of lamina; epithelial glial cell; CNS glial cell; neuropil; eye photoreceptor cell; adult brain. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Acyl transferase/acyl hydrolase/lysophospholipase; Cyclic nucleotide-binding domain; Cyclic nucleotide-binding-like; Lysophospholipase patatin, conserved site; Patatin/Phospholipase A2-related; RmlC-like jelly roll fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult central nervous system, adult heart, adult fat body, adult female reproductive system, adult testis, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval fat body, larval/adult salivary gland, larval trachea, adult male accessory gland, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1631499_a_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of sws. Gene sequence location is X:7850853..7862269.
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	olfE: olfactory-E (J.C. Hall) Larvae and adults show reduction in responses to benzaldehyde in petri-plate-based and Y-tube olfactometric assays, respectively. In odor-induced-jump assay (using benzaldehyde), mutants jump less than half as often as normal flies. allele: There is one extant allele, olfEx26. sws: swiss cheese (J.C. Hall) Isolated in anatomical screen (cf. Heisenberg and Bohl, 1979, Z. Naturforsch. 34: 143-47); many Swiss-cheese-like holes seen in brain sections of adults (similar to phenotype observed in dying drd flies).
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01	Sequence features BKN21227 HFA18843
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 7D1-7D1   Limits computationally determined from genome sequence between P{EP}EP1243 and P{EP}snEP1217
Experimentally Determined Cytological Location
Cytogenetic map Notes References 7D-7D     (Kretzschmar et al., 1995) 7D1-7D1   (determined by in situ hybridisation)   (Hasan, 1990)
Experimentally Determined Recombination Data
Location	1-22   1-23 (Ayyub et al., 1990)
Left of (cM)	sn mys fs(1)h Tbh (Monastirioti et al., 1996) v (Ayyub et al., 1990)
Right of (cM)	cv (Ayyub et al., 1990)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\sws for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	DGC clone LD36116 appears problematic: incomplete CDS
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) sws-RA FBtr0071125  NM_078520   5571   1425 sws-RB FBtr0071126  NM_167141   1771   341 sws-RC FBtr0301675  NM_167140   5571   1425
Additional Transcript Data & Comments
Reported size (kB)	5.4, 1.7 (northern blot) (Hasan, 1990)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein sws-PA   FBpp0071077   160.6   1425   7.95     NP_511075   AAF46305 sws-PB   FBpp0071078   38.8   341   4.59     NP_727225   AAN09223 sws-PC   FBpp0290889   160.7   1425   7.91     NP_727224   AAN09222
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Cyclic nucleotide-binding-like (IPR018490) Cyclic nucleotide-binding domain (IPR000595) Lysophospholipase patatin, conserved site (IPR001423) Patatin/Phospholipase A2-related (IPR002641) RmlC-like jelly roll fold (IPR014710) Acyl transferase/acyl hydrolase/lysophospholipase (IPR016035)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF46305   AE014298 AAN09222   AE014298 AAN09223   AI109400   AI456235   AI514712   AI518304   AI543350   AI945301   AJ571482   AJ571483   AJ571484   AJ571485   AJ571486   AJ571487   AJ571488   AJ571489   AJ571490   AJ571491   AJ571492   AJ571493   AJ571494   AJ571495   AJ571496   AJ571497   AJ571498   AJ571499   AJ571500   AJ571501   AJ571502   AJ571503   AJ571504   AJ571505   AW943322   AY061431 AAL28979   AY121635   BF486613   BF499017   BG636297   BG637227   BI632666   BT030819   CK658192   CK659052   CO192980   CO281226   CO282162   CO292471   CO293985   CO298090   CO299583   CO301901   CO305879   CO313602   CO313768   CO316724   CO324496   CO339624   CO340967   CZ475831   CZ475832   CZ489073   CZ489074   EC054581   EC062062   EC063796   EC065306   EC066000   EC073667   EC074798   EC078029   EC201621   EC212455   EC214048   EC216657   EC233750   EC234177   EC246177   EC248535   EC250543   EC254331   EL869871   EL872443   EL875263   EL875264   EL883992   EL883993   EL884108   EL884109   EL884236   EV583128   Z97187 CAB51772
UniProtKB/Swiss-Prot	Q9U969
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
northern blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage -- adult stage     (Hasan, 1990) adult stage   adult head   (Hasan, 1990)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0003656    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0003656 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late pupal stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0003656 expression level Developmental Stage   Expression Level embryo 00-02hr    5729 embryo 02-04hr    4290 embryo 04-06hr    2644 embryo 06-08hr    2039 embryo 08-10hr    2027 embryo 10-12hr    1632 embryo 12-14hr    1827 embryo 14-16hr    2077 embryo 16-18hr    1706 embryo 18-20hr    1449 embryo 20-22hr    1729 embryo 22-24hr    1774 larva L1    1193 larva L2    718 larva L3 12hr old    796 larva L3 puffstage 1-2    678 larva L3 puffstage 3-6    1205 larva L3 puffstage 7-9    1245 white prepupae new    1651 white prepupae 12hr    2055 white prepupae 24hr    2175 pupae 2d postWPP    2022 pupae 3d postWPP    1684 pupae 4d postWPP    4349 adult male 01day    3755 adult male 05day    4207 adult male 30day    4210 adult female 01day    3580 adult female 05day    3884 adult female 30day    4070 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (5729) embryo 02-04hr  (4290) embryo 04-06hr  (2644) embryo 06-08hr  (2039) embryo 08-10hr  (2027) embryo 10-12hr  (1632) embryo 12-14hr  (1827) embryo 14-16hr  (2077) embryo 16-18hr  (1706) embryo 18-20hr  (1449) embryo 20-22hr  (1729) embryo 22-24hr  (1774) larva L1  (1193) larva L2  (718) larva L3 12hr old  (796) larva L3 puffstage 1-2  (678) larva L3 puffstage 3-6  (1205) larva L3 puffstage 7-9  (1245) white prepupae new  (1651) white prepupae 12hr  (2055) white prepupae 24hr  (2175) pupae 2d postWPP  (2022) pupae 3d postWPP  (1684) pupae 4d postWPP  (4349) adult male 01day  (3755) adult male 05day  (4207) adult male 30day  (4210) adult female 01day  (3580) adult female 05day  (3884) adult female 30day  (4070) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (5729) embryo 02-04hr  (4290) embryo 04-06hr  (2644) embryo 06-08hr  (2039) embryo 08-10hr  (2027) embryo 10-12hr  (1632) embryo 12-14hr  (1827) embryo 14-16hr  (2077) embryo 16-18hr  (1706) embryo 18-20hr  1449 embryo 20-22hr  (1729) embryo 22-24hr  (1774) larva L1    1193 larva L2    718 larva L3 12hr old    796 larva L3 puffstage 1-2    678 larva L3 puffstage 3-6    1205 larva L3 puffstage 7-9    1245 white prepupae new  (1651) white prepupae 12hr  (2055) white prepupae 24hr  (2175) pupae 2d postWPP  (2022) pupae 3d postWPP  (1684) pupae 4d postWPP  (4349) adult male 01day  (3755) adult male 05day  (4207) adult male 30day  (4210) adult female 01day  (3580) adult female 05day  (3884) adult female 30day  (4070) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5729 embryo 02-04hr    4290 embryo 04-06hr    2644 embryo 06-08hr    2039 embryo 08-10hr    2027 embryo 10-12hr    1632 embryo 12-14hr    1827 embryo 14-16hr    2077 embryo 16-18hr    1706 embryo 18-20hr    1449 embryo 20-22hr    1729 embryo 22-24hr    1774 larva L1    1193 larva L2    718 larva L3 12hr old    796 larva L3 puffstage 1-2    678 larva L3 puffstage 3-6    1205 larva L3 puffstage 7-9    1245 white prepupae new    1651 white prepupae 12hr    2055 white prepupae 24hr    2175 pupae 2d postWPP    2022 pupae 3d postWPP    1684 pupae 4d postWPP    4349 adult male 01day    3755 adult male 05day    4207 adult male 30day    4210 adult female 01day    3580 adult female 05day    3884 adult female 30day    4070 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5729 embryo 02-04hr    4290 embryo 04-06hr    2644 embryo 06-08hr    2039 embryo 08-10hr    2027 embryo 10-12hr    1632 embryo 12-14hr    1827 embryo 14-16hr    2077 embryo 16-18hr    1706 embryo 18-20hr    1449 embryo 20-22hr    1729 embryo 22-24hr    1774 larva L1    1193 larva L2    718 larva L3 12hr old    796 larva L3 puffstage 1-2    678 larva L3 puffstage 3-6    1205 larva L3 puffstage 7-9    1245 white prepupae new    1651 white prepupae 12hr    2055 white prepupae 24hr    2175 pupae 2d postWPP    2022 pupae 3d postWPP    1684 pupae 4d postWPP    4349 adult male 01day    3755 adult male 05day    4207 adult male 30day    4210 adult female 01day    3580 adult female 05day    3884 adult female 30day    4070 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0003656 expression level Developmental Stage   Expression Level embryo 00-02hr    5729 embryo 02-04hr    4290 embryo 04-06hr    2644 embryo 06-08hr    2039 embryo 08-10hr    2027 embryo 10-12hr    1632 embryo 12-14hr    1827 embryo 14-16hr    2077 embryo 16-18hr    1706 embryo 18-20hr    1449 embryo 20-22hr    1729 embryo 22-24hr    1774 larva L1    1193 larva L2    718 larva L3 12hr old    796 larva L3 puffstage 1-2    678 larva L3 puffstage 3-6    1205 larva L3 puffstage 7-9    1245 white prepupae new    1651 white prepupae 12hr    2055 white prepupae 24hr    2175 pupae 2d postWPP    2022 pupae 3d postWPP    1684 pupae 4d postWPP    4349 adult male 01day    3755 adult male 05day    4207 adult male 30day    4210 adult female 01day    3580 adult female 05day    3884 adult female 30day    4070 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (5729) embryo 02-04hr  (4290) embryo 04-06hr  (2644) embryo 06-08hr  (2039) embryo 08-10hr  (2027) embryo 10-12hr  (1632) embryo 12-14hr  (1827) embryo 14-16hr  (2077) embryo 16-18hr  (1706) embryo 18-20hr  (1449) embryo 20-22hr  (1729) embryo 22-24hr  (1774) larva L1  (1193) larva L2  (718) larva L3 12hr old  (796) larva L3 puffstage 1-2  (678) larva L3 puffstage 3-6  (1205) larva L3 puffstage 7-9  (1245) white prepupae new  (1651) white prepupae 12hr  (2055) white prepupae 24hr  (2175) pupae 2d postWPP  (2022) pupae 3d postWPP  (1684) pupae 4d postWPP  (4349) adult male 01day  (3755) adult male 05day  (4207) adult male 30day  (4210) adult female 01day  (3580) adult female 05day  (3884) adult female 30day  (4070) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (5729) embryo 02-04hr  (4290) embryo 04-06hr  (2644) embryo 06-08hr  2039 embryo 08-10hr  2027 embryo 10-12hr  1632 embryo 12-14hr  1827 embryo 14-16hr  2077 embryo 16-18hr  1706 embryo 18-20hr  1449 embryo 20-22hr  1729 embryo 22-24hr  1774 larva L1    1193 larva L2    718 larva L3 12hr old    796 larva L3 puffstage 1-2    678 larva L3 puffstage 3-6    1205 larva L3 puffstage 7-9    1245 white prepupae new  1651 white prepupae 12hr  2055 white prepupae 24hr  2175 pupae 2d postWPP  2022 pupae 3d postWPP  1684 pupae 4d postWPP  (4349) adult male 01day  (3755) adult male 05day  (4207) adult male 30day  (4210) adult female 01day  (3580) adult female 05day  (3884) adult female 30day  (4070) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5729 embryo 02-04hr    4290 embryo 04-06hr    2644 embryo 06-08hr    2039 embryo 08-10hr    2027 embryo 10-12hr    1632 embryo 12-14hr    1827 embryo 14-16hr    2077 embryo 16-18hr    1706 embryo 18-20hr    1449 embryo 20-22hr    1729 embryo 22-24hr    1774 larva L1    1193 larva L2    718 larva L3 12hr old    796 larva L3 puffstage 1-2    678 larva L3 puffstage 3-6    1205 larva L3 puffstage 7-9    1245 white prepupae new    1651 white prepupae 12hr    2055 white prepupae 24hr    2175 pupae 2d postWPP    2022 pupae 3d postWPP    1684 pupae 4d postWPP    4349 adult male 01day    3755 adult male 05day    4207 adult male 30day    4210 adult female 01day    3580 adult female 05day    3884 adult female 30day    4070 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5729 embryo 02-04hr    4290 embryo 04-06hr    2644 embryo 06-08hr    2039 embryo 08-10hr    2027 embryo 10-12hr    1632 embryo 12-14hr    1827 embryo 14-16hr    2077 embryo 16-18hr    1706 embryo 18-20hr    1449 embryo 20-22hr    1729 embryo 22-24hr    1774 larva L1    1193 larva L2    718 larva L3 12hr old    796 larva L3 puffstage 1-2    678 larva L3 puffstage 3-6    1205 larva L3 puffstage 7-9    1245 white prepupae new    1651 white prepupae 12hr    2055 white prepupae 24hr    2175 pupae 2d postWPP    2022 pupae 3d postWPP    1684 pupae 4d postWPP    4349 adult male 01day    3755 adult male 05day    4207 adult male 30day    4210 adult female 01day    3580 adult female 05day    3884 adult female 30day    4070 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0003656    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0003656 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult central nervous system, adult heart, adult fat body, adult female reproductive system, adult testis, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval fat body, larval/adult salivary gland, larval trachea, adult male accessory gland, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0003656 expression level Tissue   Expression Level Larval Central Nervous System    407.025 Larval Midgut    232.5 Larval Hindgut    243.6 Larval Malpighian Tubules    183.4 Larval Fat Body    271.2 Larval Salivary Gland    107.1 Larval Trachea    176.075 Larval Carcass    188.875 Adult Head    586 Adult Eye    390.025 Adult Brain    880 Adult Thoracic-Abdominal Ganglion    1067.9 Adult Crop    231.1 Adult Midgut    236.3 Adult Hindgut    204.2 Adult Malpighian Tubules    244.8 Adult Fat Body    1188.3 Adult Salivary Gland    152.3 Adult Heart    712.5 Adult VirginFemale Spermatheca    728.7 Adult InseminatedFemale Spermatheca    613.5 Adult Ovary    793.5 Adult Testis    816.2 Adult Male Accessory Gland    239 Adult Carcass    721.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    407.025 Larval Midgut    232.5 Larval Hindgut    243.6 Larval Malpighian Tubules    183.4 Larval Fat Body    271.2 Larval Salivary Gland    107.1 Larval Trachea    176.075 Larval Carcass    188.875 Adult Head  (586) Adult Eye    390.025 Adult Brain  (880) Adult Thoracic-Abdominal Ganglion  (1067.9) Adult Crop    231.1 Adult Midgut    236.3 Adult Hindgut    204.2 Adult Malpighian Tubules    244.8 Adult Fat Body  (1188.3) Adult Salivary Gland    152.3 Adult Heart  (712.5) Adult VirginFemale Spermatheca  (728.7) Adult InseminatedFemale Spermatheca  (613.5) Adult Ovary  (793.5) Adult Testis  (816.2) Adult Male Accessory Gland    239 Adult Carcass  (721.5) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    407.025 Larval Midgut    232.5 Larval Hindgut    243.6 Larval Malpighian Tubules    183.4 Larval Fat Body    271.2 Larval Salivary Gland    107.1 Larval Trachea    176.075 Larval Carcass    188.875 Adult Head    586 Adult Eye    390.025 Adult Brain    880 Adult Thoracic-Abdominal Ganglion  1067.9 Adult Crop    231.1 Adult Midgut    236.3 Adult Hindgut    204.2 Adult Malpighian Tubules    244.8 Adult Fat Body  (1188.3) Adult Salivary Gland    152.3 Adult Heart    712.5 Adult VirginFemale Spermatheca    728.7 Adult InseminatedFemale Spermatheca    613.5 Adult Ovary    793.5 Adult Testis    816.2 Adult Male Accessory Gland    239 Adult Carcass    721.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    407.025 Larval Midgut    232.5 Larval Hindgut    243.6 Larval Malpighian Tubules    183.4 Larval Fat Body    271.2 Larval Salivary Gland    107.1 Larval Trachea    176.075 Larval Carcass    188.875 Adult Head    586 Adult Eye    390.025 Adult Brain    880 Adult Thoracic-Abdominal Ganglion    1067.9 Adult Crop    231.1 Adult Midgut    236.3 Adult Hindgut    204.2 Adult Malpighian Tubules    244.8 Adult Fat Body    1188.3 Adult Salivary Gland    152.3 Adult Heart    712.5 Adult VirginFemale Spermatheca    728.7 Adult InseminatedFemale Spermatheca    613.5 Adult Ovary    793.5 Adult Testis    816.2 Adult Male Accessory Gland    239 Adult Carcass    721.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0003656 expression level Tissue   Expression Level Larval Central Nervous System    407.025 Larval Midgut    232.5 Larval Hindgut    243.6 Larval Malpighian Tubules    183.4 Larval Fat Body    271.2 Larval Salivary Gland    107.1 Larval Trachea    176.075 Larval Carcass    188.875 Adult Head    586 Adult Eye    390.025 Adult Brain    880 Adult Thoracic-Abdominal Ganglion    1067.9 Adult Crop    231.1 Adult Midgut    236.3 Adult Hindgut    204.2 Adult Malpighian Tubules    244.8 Adult Fat Body    1188.3 Adult Salivary Gland    152.3 Adult Heart    712.5 Adult VirginFemale Spermatheca    728.7 Adult InseminatedFemale Spermatheca    613.5 Adult Ovary    793.5 Adult Testis    816.2 Adult Male Accessory Gland    239 Adult Carcass    721.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    407.025 Larval Midgut    232.5 Larval Hindgut    243.6 Larval Malpighian Tubules    183.4 Larval Fat Body    271.2 Larval Salivary Gland    107.1 Larval Trachea    176.075 Larval Carcass    188.875 Adult Head  586 Adult Eye    390.025 Adult Brain  (880) Adult Thoracic-Abdominal Ganglion  (1067.9) Adult Crop    231.1 Adult Midgut    236.3 Adult Hindgut    204.2 Adult Malpighian Tubules    244.8 Adult Fat Body  (1188.3) Adult Salivary Gland    152.3 Adult Heart  712.5 Adult VirginFemale Spermatheca  728.7 Adult InseminatedFemale Spermatheca  613.5 Adult Ovary  793.5 Adult Testis  (816.2) Adult Male Accessory Gland    239 Adult Carcass  721.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    407.025 Larval Midgut    232.5 Larval Hindgut    243.6 Larval Malpighian Tubules    183.4 Larval Fat Body    271.2 Larval Salivary Gland    107.1 Larval Trachea    176.075 Larval Carcass    188.875 Adult Head    586 Adult Eye    390.025 Adult Brain    880 Adult Thoracic-Abdominal Ganglion  1067.9 Adult Crop    231.1 Adult Midgut    236.3 Adult Hindgut    204.2 Adult Malpighian Tubules    244.8 Adult Fat Body  1188.3 Adult Salivary Gland    152.3 Adult Heart    712.5 Adult VirginFemale Spermatheca    728.7 Adult InseminatedFemale Spermatheca    613.5 Adult Ovary    793.5 Adult Testis    816.2 Adult Male Accessory Gland    239 Adult Carcass    721.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    407.025 Larval Midgut    232.5 Larval Hindgut    243.6 Larval Malpighian Tubules    183.4 Larval Fat Body    271.2 Larval Salivary Gland    107.1 Larval Trachea    176.075 Larval Carcass    188.875 Adult Head    586 Adult Eye    390.025 Adult Brain    880 Adult Thoracic-Abdominal Ganglion    1067.9 Adult Crop    231.1 Adult Midgut    236.3 Adult Hindgut    204.2 Adult Malpighian Tubules    244.8 Adult Fat Body    1188.3 Adult Salivary Gland    152.3 Adult Heart    712.5 Adult VirginFemale Spermatheca    728.7 Adult InseminatedFemale Spermatheca    613.5 Adult Ovary    793.5 Adult Testis    816.2 Adult Male Accessory Gland    239 Adult Carcass    721.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    586   NA  Eye    390.025   NA  Brain    880   407.025  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    1067.9   NA  Crop    231.1   232.5  Midgut    236.3   243.6  Hindgut    204.2   183.4  Malpighian Tubules    244.8   271.2  Fat Body    1188.3   107.1  Salivary Gland    152.3   NA  Heart    712.5   176.075  Trachea    NA   NA  VirginFemale Spermatheca    728.7   NA  InseminatedFemale Spermatheca    613.5   NA  Ovary    793.5   NA  Testis    816.2   NA  Male Accessory Gland    239   188.875  Carcass    721.5 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_26
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0003656 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG2212-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable swsCC01711 viable, with Scer\GAL4pnr-MD237 swsGD3277 Other Phenotypes Allele neuroanatomy defective sws1 neuroanatomy defective, with Scer\GAL4GMR.PF swsScer\UAS.cMa neuroanatomy defective, with Scer\GAL4loco.1.3 swsScer\UAS.cMa short lived sws4 sws5 sws6 smell perception defective swsolfE-x26 smell perception defective | recessive swsolfE-x26 Phenotype manifest in Allele adult brain sws1 CNS glial cell sws1 CNS glial cell, with Scer\GAL4loco.1.3 swsScer\UAS.cMa cortex of lamina sws1 epithelial glial cell, with Scer\GAL4loco.1.3 swsScer\UAS.cMa eye photoreceptor cell, with Scer\GAL4GMR.PF swsScer\UAS.cMa neuropil sws1
Classical Alleles ( 15 )
For All Classical Alleles Show
Allele of sws Class Mutagen Stocks Known lesion swsolfE-x26 amorphic allele - genetic evidence ethyl methanesulfonate 1 -- sws4 1 Yes swsd07605 P-element activity 1 -- swsf06375 piggyBac transposase 1 -- swsG17521 P-element activity 1 -- swsG17614 P-element activity 1 -- swsG983 P-element activity 1 -- swsNP4072 1 -- sws1 ethyl methanesulfonate 0 Yes sws2 ethyl methanesulfonate 0 -- sws3 ethyl methanesulfonate 0 -- sws5 0 Yes sws6 0 -- swsCC01711 P-element activity 0 Yes swsunspecified 0 --
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of sws Class Mutagen Stocks Known lesion swsGD3277 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes swsJF03428 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes swsolfE-E2 in vitro construct - genomic fragment 0 Yes swsS985D.Scer\UAS in vitro construct - regulatory fusion in vitro construct - site directed mutagenesis 0 Yes swsScer\UAS.cMa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(1)C128 (Hasan, 1989, Ayyub et al., 1990, Hasan, 1990, Monastirioti et al., 1996, Kretzschmar et al., 1997) Df(1)sn-13a1 (Hasan, 1989, Hasan, 1990) Df(1)sn+72d (Hasan, 1989, Hasan, 1990)
Duplicated in	Dp(1;2)sn+72d (Ayyub et al., 1990, Monastirioti et al., 1996) Dp(1;3)sn13a1 (Hasan, 1990, Kretzschmar et al., 1997) Tp(1;3)sn13a1 (Hasan, 1990)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD3277} NA P{TRiP.JF03428} NA P{UAS-sws.M} NA P{UAS-sws.S985D} NA characterization construct P{Car20-E2} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap binary system P{GawB}swsNP4072 No miscellaneous insertions P{PTT-GC}swsCC01711 NA PBac{WH}swsf06375 NA insertion of mobile activating element P{EP}snG983 NA P{EP}swsG17521 NA P{EP}swsG17614 NA P{XP}swsd07605 NA
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 5 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
cellular membrane organization inferred from direct assay (Muhlig-Versen et al., 2005) membrane lipid metabolic process inferred from direct assay (Muhlig-Versen et al., 2005) neuron apoptosis inferred from mutant phenotype (Muhlig-Versen et al., 2005) phosphatidylcholine metabolic process inferred from direct assay (Muhlig-Versen et al., 2005) sensory perception of smell inferred from mutant phenotype (Ayyub and Paranjape, 2002)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
lysophospholipase activity inferred from electronic annotation with InterPro:IPR001423 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
brain development non-traceable author statement (Swiss-Prot Project Members, 2000.10.1)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions sws allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0003656 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31716
Orthologs
Genome-wide drosophilid orthologs	Dana\GF20991 Dere\GG17592 Dgri\GH24540 Dmoj\GI21654 Dper\GL15243 Dpse\GA22927 Dsec\GM11957 Dsim\sws Dvir\GJ16892 Dwil\GK16217 Dyak\GE17492
Curated drosophilid orthologs	Dsim\sws
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL013811-PA Aedes aegypti (mosquito) AGAP000467-PA Anopheles gambiae (mosquito) XP_001120383.1 Apis mellifera (honey bee) XP_001951676.1 Acyrthosiphon pisum (pea aphid) 9648 Batrachochytrium dendrobatidis (chytrid fungus) 173772 Branchiostoma floridae (lancelet) XP_001891704.1 Brugia malayi (roundworm nematode) ENSBTAP00000016089 Bos taurus (bovine) CAL0001431 Candida albicans (a form of yeast) CN28555 Caenorhabditis brenneri (small nematode) CBP26622 Caenorhabditis briggsae (nematode) CE34455 Caenorhabditis elegans (worm) ENSCAFP00000028715 Canis familiaris (dog) CAGL0L11154g Candida glabrata (haploid yeast) ENSCINP00000013466 Ciona intestinalis (sea squirt) JA17647 Caenorhabditis japonica (nematode) cn04217 Cryptococcus neoformans (yeast-like fungus) CPIJ003198 Culex pipens (mosquito) ENSCPOP00000000497 Cavia porcellus (guinea pig) RP37998 Caenorhabditis remanei (nematode) ENSCSAVP00000011060 Ciona savignyi (sedentary tunicate) 138805 Capitella spl (polychaete worm) DEHA2E04400g Debaryomyces Hansenii (yeast) 325592 Daphnia pulex (daphnia) ENSDARP00000010678 Danio rerio (zebra fish) ENSECAP00000011201 Equus caballus (horse) ENSGACP00000024694 Gymnopilus aculeatus (mushroom) ENSGALP00000014200 Gallus gallus (chicken) 67348 Hypsipyla robusta (cedar shoot borer) ENSP00000277531 Homo sapiens (human) KLLA0B05225g Kluyveromyces lactis (yeast) 61439 Lottia gigantea (owl limpet) ENSMODP00000021410 Monodelphis domestica (gray opossum) ENSMMUP00000025749 Macaca mulatta (rhesus monkey) ENSMUSP00000044078 Mus musculus (house mouse) 115565 Nematostella vectensis (starlet anemone) XP_001605101.1 Nasonia vitripennis (wasp) ENSOANP00000001869 Ornithorynchus anatinus (platypus) ENSORLP00000021011 Oryzias latipes (japanese killifish) 31748 Ostreococcus tauri (green alga) PHUM004092-PA Pediculus humanus (human body louse) ENSPPYP00000010626 Pongo pygmaeus (orangutan) 72719 Phytophthora ramorum (sudden oak death pathogen) 130240 Phytophthora sojae (root rot pathogen) ENSPTRP00000017679 Pan troglodytes (chimpanzee) ENSRNOP00000011633 Rattus norvegicus (norway rat) YML059C Saccharomyces cerevisiae (budding yeast) Smp_171820.2 Schistosoma mansoni (trematode parasite) SPCC4B3.04c Schizosaccharomyces pombe (fission yeast) XP_001202094.1 Strongylocentrotus purpuratus (purple sea urchin) 10294 Trichoplax adhaerens (metazoa) ENSTNIP00000005461 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000020290 Takifugu rubripes (pufferfish Takifugu) YALI0B11044g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB13690 NV11144 LH18970 FBgn0234955 FBgn0218219 FBgn0204071 FBgn0068584 FBgn0166898 JGI_V11_325592 FBgn0244329 FBgn0152847 FBgn0144384 FBgn0131996 FBgn0109816 FBgn0097996 CPIJ003198 BGIBMGA007928 BGIBMGA007927 ACYPI009511 GB10208 AGAP000467 AAEL013811 PHUM488870 GLEAN_01035
Stocks & Reagents
Stocks Listed in FlyBase ( 10 )
Bloomington	1015 swsolfE-x26 33321 w* P{EP}swsG17521 33325 w* P{EP}swsG17614 31993 y1 v1; P{TRiP.JF03428}attP2 33552 w* P{EP}snG983 swsG983 28121 sws4/C(1)DX, y1 w1 f1
Harvard	- P{XP}swsd07605 - PBac{WH}swsf06375
Kyoto	104592 y* w* P{GawB}swsNP4072 / FM7c
VDRC	v5469 w1118; P{GD3277}v5469
Genomic Clones ( 1 )
	BACR24A02 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 55 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH25996 GM04921 LD36116
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT13501 AT21047 GH08579 LD37778 LD41208 LP14940 LP16496 SD10078 SD13934 SD15112 SD26496
Other clones	39273 44453 47564 47592 58994 66137 71880 74122 79207 107181 107694 107813 146844 162249 179651 214225.14 277559 bs11c01 Dmel_dig_006479_0639_2315 EC34938 EC054581 EK156235 EK159660 EK171440 EK175850 EK182533 EK193944 EK200249 EK205309 EK233538 EK234028 EK249618 EK265725 EP02415 EP11642 IP01987 IP04362 IP15269 IP15369 IP15469 IP15569
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0003656 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31716
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: sws CG2212 (Zhang, 1999.11)
Source for database merge of
Additional comments	complements olfA, olfB and olfF.
Other Comments
	sws is essential for membrane lipid homeostasis and cell survival in both neurons and glia. (Muhlig-Versen et al., 2005) sws mutants are characterised by progressive degeneration of the adult nervous system, glial hyperwrapping, and neuronal apoptosis. (Muhlig-Versen et al., 2005)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_078520 NM_167140 NM_167141 RefSeq (Proteins) • NP_511075 NP_727224 NP_727225 DDBJ / EMBL / GenBank • AAF46305 AAL28979 AAN09222 AAN09223 AI456235 AI518304 AI945301 AJ571482 AJ571483 AJ571484 AJ571485 AJ571486 AJ571487 AJ571488 AJ571489 AJ571490 AJ571491 AJ571492 AJ571493 AJ571494 AJ571495 AJ571496 AJ571497 AJ571498 AJ571499 AJ571500 AJ571501 AJ571502 AJ571503 AJ571504 AJ571505 AW943322 AY061431 CAB51772 CZ475831 CZ475832 CZ489073 CZ489074 Z97187 Entrez Gene - A searchable database of RefSeq genes. • 31716 UniProtKB/Swiss-Prot • Q9U969
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Cyclic nucleotide-binding-like (IPR018490) Cyclic nucleotide-binding domain (IPR000595) Lysophospholipase patatin, conserved site (IPR001423) Patatin/Phospholipase A2-related (IPR002641) RmlC-like jelly roll fold (IPR014710) Acyl transferase/acyl hydrolase/lysophospholipase (IPR016035)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0003656 DRSC - Results from RNAi screens. • FBgn0003656 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0003656 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG2212-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0003656 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31716 InParanoid A subset of ortholog calls from InParanoid. • AAEL013811-PA Aedes aegypti (mosquito) AGAP000467-PA Anopheles gambiae (mosquito) XP_001120383.1 Apis mellifera (honey bee) XP_001951676.1 Acyrthosiphon pisum (pea aphid) 9648 Batrachochytrium dendrobatidis (chytrid fungus) 173772 Branchiostoma floridae (lancelet) XP_001891704.1 Brugia malayi (roundworm nematode) ENSBTAP00000016089 Bos taurus (bovine) CAL0001431 Candida albicans (a form of yeast) CN28555 Caenorhabditis brenneri (small nematode) CBP26622 Caenorhabditis briggsae (nematode) CE34455 Caenorhabditis elegans (worm) ENSCAFP00000028715 Canis familiaris (dog) CAGL0L11154g Candida glabrata (haploid yeast) ENSCINP00000013466 Ciona intestinalis (sea squirt) JA17647 Caenorhabditis japonica (nematode) cn04217 Cryptococcus neoformans (yeast-like fungus) CPIJ003198 Culex pipens (mosquito) ENSCPOP00000000497 Cavia porcellus (guinea pig) RP37998 Caenorhabditis remanei (nematode) ENSCSAVP00000011060 Ciona savignyi (sedentary tunicate) 138805 Capitella spl (polychaete worm) DEHA2E04400g Debaryomyces Hansenii (yeast) 325592 Daphnia pulex (daphnia) ENSDARP00000010678 Danio rerio (zebra fish) ENSECAP00000011201 Equus caballus (horse) ENSGACP00000024694 Gymnopilus aculeatus (mushroom) ENSGALP00000014200 Gallus gallus (chicken) 67348 Hypsipyla robusta (cedar shoot borer) ENSP00000277531 Homo sapiens (human) KLLA0B05225g Kluyveromyces lactis (yeast) 61439 Lottia gigantea (owl limpet) ENSMODP00000021410 Monodelphis domestica (gray opossum) ENSMMUP00000025749 Macaca mulatta (rhesus monkey) ENSMUSP00000044078 Mus musculus (house mouse) 115565 Nematostella vectensis (starlet anemone) XP_001605101.1 Nasonia vitripennis (wasp) ENSOANP00000001869 Ornithorynchus anatinus (platypus) ENSORLP00000021011 Oryzias latipes (japanese killifish) 31748 Ostreococcus tauri (green alga) PHUM004092-PA Pediculus humanus (human body louse) ENSPPYP00000010626 Pongo pygmaeus (orangutan) 72719 Phytophthora ramorum (sudden oak death pathogen) 130240 Phytophthora sojae (root rot pathogen) ENSPTRP00000017679 Pan troglodytes (chimpanzee) ENSRNOP00000011633 Rattus norvegicus (norway rat) YML059C Saccharomyces cerevisiae (budding yeast) Smp_171820.2 Schistosoma mansoni (trematode parasite) SPCC4B3.04c Schizosaccharomyces pombe (fission yeast) XP_001202094.1 Strongylocentrotus purpuratus (purple sea urchin) 10294 Trichoplax adhaerens (metazoa) ENSTNIP00000005461 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000020290 Takifugu rubripes (pufferfish Takifugu) YALI0B11044g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31716 modMine - Data generated by the modENCODE project. • FBgn0003656 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB13690 NV11144 LH18970 FBgn0234955 FBgn0218219 FBgn0204071 FBgn0068584 FBgn0166898 JGI_V11_325592 FBgn0244329 FBgn0152847 FBgn0144384 FBgn0131996 FBgn0109816 FBgn0097996 CPIJ003198 BGIBMGA007928 BGIBMGA007927 ACYPI009511 GB10208 AGAP000467 AAEL013811 PHUM488870 GLEAN_01035
Synonyms & Secondary IDs ( 11 )
Reported As
Symbol Synonym	CG2212 (Perkins et al., 2009) olfE (Smith, 1996, Monastirioti et al., 1996, Carlson, 1996, Griff and Reed, 1995, Cant et al., 1994, Paterson and O'Hare, 1991, Vijay Raghavan et al., 1991, Ayyub et al., 1990, Ayyub and Paranjape, 2002, Lindsley and Zimm, 1992) sws (Wentzell et al., 2007, Ayyub and Paranjape, 2002, Buszczak et al., 2007, Muhlig-Versen et al., 2005, Lindsley and Zimm, 1992, Bettencourt da Cruz et al., 2008) Sws (Zhang et al., 2002)
Name Synonym	olfactory E   olfactory-E (Lindsley and Zimm, 1992) swiss cheese (Kretzschmar, 1997.6.24, Wentzell et al., 2007, Lindsley and Zimm, 1992, Carbone et al., 2009) swisscheese (Ayyub and Paranjape, 2002) Swiss cheese (Muhlig-Versen et al., 2005) Swiss Cheese (Bettencourt da Cruz et al., 2008) Swisscheese (Pospisilik et al., 2010)
Secondary FlyBase IDs
	FBgn0004059
References ( 49 )
Generate a list of	All references relating to this gene ( 49 )
List References by type	Research paper  ( 17 ) Supplementary material  ( 2 ) Review  ( 9 ) Personal communication to FlyBase  ( 6 ) Abstract  ( 4 ) FlyBase analysis  ( 2 ) DNA/RNA sequence record  ( 1 ) Book  ( 1 ) Curated genome annotation  ( 1 ) Protein sequence record  ( 1 ) Computer file  ( 3 ) Letter  ( 1 )
Recent research papers ( 1 )
	Pospisilik et al., 2010, Cell 140(1): 148--160 Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate. [FBrf0212676] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...