VAMP, Complementation group J
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Gene model reviewed during 5.49
Low-frequency RNA-Seq exon junction(s) not annotated.
0.9, 0.85 (northern blot)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Syb using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Syb in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
The Syb gene product is essential for transmission and is required for calcium-dependent vesicle fusion.
Syb gene comprises 5 exons, alternative splicing generates 2 transcripts, the ratio of these transcripts is highly regulated during development. Syb expression pattern suggests Syb may have a general role in membrane trafficking and perhaps a role in the secretion of digestive enzymes.
Complementation group identified in an EMS and DEB screen to isolate deficiencies that uncover Jra.
Identification: First isolated from a Drosophila cDNA library using a bovine cDNA probe.
Encodes a 20kD polypeptide that is recognized by antibodies to rat synaptobrevin.