• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\tu(1)Sz

General Information
Symbol	Dmel\tu(1)Sz	Species	D. melanogaster
Name	tumor (1) Sz	Annotation symbol
Feature type	gene	FlyBase ID	FBgn0003875
Gene Model Status	Unannotated	Stock availability	1 publicly available
Also Known As	Tu-Sz
Genomic Location
Chromosome (arm)		Recombination map	1-34.3
Cytogenetic map	10B1-10B4	Sequence location
Summary Information
Automatically generated summary See sections below for more information	The gene tumor (1) Sz is referred to in FlyBase by the symbol Dmel\tu(1)Sz (FBgn0003875). It is a gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has no annotated transcripts. Gene has not been localized to the genome sequence.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 10B1-10B4   Left limit from complementation mapping against T(1;Y;3)154 (citation unavailable) Right limit from complementation mapping relative to l(1)10Bc (citation unavailable)
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location	1-34.3
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa)
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Mapped Features
Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
modENCODE Anatomy RNA-Seq
modENCODE Development RNA-Seq
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
Expression Clusters
External Data & Images
Linkouts
Alleles & Phenotypes
Summary of Allele Phenotypes
Other Phenotypes Allele visible | heat sensitive tu(1)Sz1 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of tu(1)Sz Class Mutagen Stocks Known lesion tu(1)Sz1 ethyl methanesulfonate 1 --
Alleles Carried on Transgenic Constructs ( 0 )
For All Alleles Carried on Transgenic Constructs Show
Allele of tu(1)Sz Class Mutagen Stocks Known lesion
Aneuploid Aberrations
Disrupted in	Df(1)KA7 (Zhimulev et al., 1987) Df(1)RA37 (Zhimulev et al., 1987)
Duplicated in	Dp(1;2)v+65b (Zhimulev et al., 1987) Dp(1;Y)v+y+ (Zhimulev et al., 1987) Dp(1;Y)v+y+366 (Zhimulev et al., 1987)
Not disrupted in	Df(1)59D3 (Zhimulev et al., 1987) Df(1)203C10 (Zhimulev et al., 1987) Df(1)HC133 (Zhimulev et al., 1987) Df(1)N71 (Zhimulev et al., 1987) Df(1)ras-P14 (Zhimulev et al., 1987) Df(1)ras-v17 (Zhimulev et al., 1987) Df(1)ras-v-P26 (Zhimulev et al., 1987) Df(1)sbr1 (Zhimulev et al., 1987) Df(1)sbr8 (Zhimulev et al., 1987) Df(1)sbr9 (Zhimulev et al., 1987) Df(1)sbr10 (Zhimulev et al., 1987) Df(1)v64f (Zhimulev et al., 1987) Df(1)v-B151 (Zhimulev et al., 1987) Df(1)v-L1 (Zhimulev et al., 1987) Df(1)v-L2 (Zhimulev et al., 1987) Df(1)v-L3 (Zhimulev et al., 1987) Df(1)v-L4 (Zhimulev et al., 1987) Df(1)v-L7 (Zhimulev et al., 1987) Df(1)v-L11 (Zhimulev et al., 1987) Df(1)v-L15 (Zhimulev et al., 1987) Df(1)v-M1 (Zhimulev et al., 1987) Df(1)v-M5 (Zhimulev et al., 1987) Df(1)v-M6 (Zhimulev et al., 1987) Df(1)v-M7 (Zhimulev et al., 1987) Df(1)v-P5 (Zhimulev et al., 1987) Df(1)v-P16 (Zhimulev et al., 1987) Df(1)v-P22 (Zhimulev et al., 1987)
Not duplicated in	Dp(1;2)v+63i (Zhimulev et al., 1987) Dp(1;Y)dsh+y+ (Zhimulev et al., 1987) Dp(1;Y)v+y+U15 (Zhimulev et al., 1987)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions tu(1)Sz allele Gene References
External Data
Linkouts
Orthologs
OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search No orthologs identified Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (None identified)
No orthologies identified
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 1 )
Bloomington	5834 tu(1)Sz1
Genomic Clones ( 0 )
cDNA Clones ( 0 )
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts	GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 48534
Antibody Information
Other Information
Discoverer
	Suzuki.
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	One of several loci at which mutations result in melanotic masses (tumors).
External Crossreferences & Linkouts
Sequence Crossreferences
Other Crossreferences
Linkouts
	GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 48534
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	tu(1)Sz (Rizki et al., 1985) Tu-Sz (Brennan and Anderson, 2004) tu-Sz (Dearolf, 1998, Rizki and Rizki, 1991, Rizki and Rizki, 1990, )
Name Synonym	tumor (1) Sz
Secondary FlyBase IDs
References ( 14 )
Research paper	Rizki and Rizki, 1991, J. exp. Zool. 257(2): 236--244 Effects of lamellolysin from a parasitoid wasp on Drosophila blood cells in vitro. [FBrf0054540] Rizki and Rizki, 1990, Experientia 46: 311--315 Microtubule inhibitors block the morphological changes induced in Drosophila blood cells by a parasitoid wasp factor. [FBrf0051745] Rizki and Rizki, 1990, J. Insect Physiol. 36(7): 523--529 Encapsulation of parasitoid eggs in phenol oxidase-deficient mutants of Drosophila melanogaster. [FBrf0052363] Zhimulev et al., 1987, Biol. Zentbl. 106(6): 699--720 Fine cytogenetical analysis of the band 10A1-2 and the adjoining regions in the Drosophila melanogaster X-chromosome. [FBrf0045718] Rizki et al., 1985, Mol. Gen. Genet. 201: 7--13 Genetics of a Drosophila phenoloxidase. [FBrf0043263] Rizki et al., 1983, Rouxs Arch. Dev. Biol. 192(1): 1--7 Drosophila larval fat body surfaces. Changes in transplant compatibility during development. [FBrf0040169] Rizki and Rizki, 1980, Rouxs Arch. Dev. Biol. 189(3): 197--206 Developmental analysis of a temperature-sensitive melanotic tumor mutant in Drosophila melanogaster. [FBrf0035577] Rizki and Rizki, 1959, J. biophys. biochem. Cytol. 5: 235--240, 2 plates Functional significance of the crystal cells in the larva of Drosophila melanogaster. [FBrf0012723]
Review	Brennan and Anderson, 2004, A. Rev. Immunol. 22: 457--483 Drosophila: the genetics of innate immune recognition and response. [FBrf0174342] Lavine and Strand, 2002, Insect Biochem. Mol. Biol. 32(10): 1295--1309 Insect hemocytes and their role in immunity. [FBrf0155844] Dearolf, 1998, Biochim. Biophys. Acta 1377(1): M13--M23 Fruit fly 'leukemia'. [FBrf0102303]
Abstract	Rizki and Rizki, 1979, Genetics 91(4/2): s103--s104 Phenogenetics of Black cells (Bc). [FBrf0033223]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]
Teaching note	Perez-Chiesa, 1999, D. I. S. 82: 131--132 Incidence of Drosophila melanogaster flies with melanotic tumors for demonstrating conditionality, penetrance and variable expression. [FBrf0112003]