Gene Dmel\tu(2)W

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General Information

Symbol

Dmel\tu(2)W

Species

D. melanogaster

Name

tumor(2)W

Annotation symbol

Feature type

gene

FlyBase ID

FBgn0003879

Gene Model Status

Unannotated

Stock availability

1 publicly available

Also Known As

tu-W

Genomic Location

Chromosome (arm)

Recombination map

2-66.2

Cytogenetic map

Sequence location

Summary Information

Automatically generated summary

See sections below for more information

The gene tumor(2)W is referred to in FlyBase by the symbol Dmel\tu(2)W (FBgn0003879). It is a gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has no annotated transcripts. Gene has not been localized to the genome sequence.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-66.2

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Mapped Features

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

modENCODE Anatomy RNA-Seq

modENCODE Development RNA-Seq

modENCODE Cell Lines RNA-Seq

modENCODE Treatments RNA-Seq

Expression Clusters

External Data & Images

Linkouts

Alleles & Phenotypes

Summary of Allele Phenotypes

Other Phenotypes

Allele

melanotic mass phenotype

Phenotype manifest in

Allele

Classical Alleles ( 2 )

For All Classical Alleles Show

Allele of tu(2)W	Class	Mutagen	Stocks	Known lesion
tu(2)W^g			1	--
tu(2)W¹		1,2:5,6-dibenzanthracene	0	--

Alleles Carried on Transgenic Constructs ( 0 )

For All Alleles Carried on Transgenic Constructs Show

Allele of tu(2)W	Class	Mutagen	Stocks	Known lesion

Aneuploid Aberrations

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

Insertions

Type of insertions

Name

Expression data

Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 0 terms )

Sequence Ontology: Class of Gene

gene

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

tu(2)W allele

Gene

References

External Data

Linkouts

Orthologs

OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

No orthologs identified

Dipteran inclusive ortholog search

No orthologs identified

Insect inclusive ortholog search

No orthologs identified

Arthropod inclusive ortholog search

No orthologs identified

Metazoa inclusive ortholog search

No orthologs identified

Orthologs in Drosophila Species (None identified)

No orthologies identified

Orthologs in non-Drosophila Dipterans (None identified)

No non-Drosophilid orthologies identified

Orthologs in non-Dipteran Insects (None identified)

No non-Dipteran orthologies identified

Orthologs in non-Insect Arthropods (None identified)

No non-Insect Arthropod orthologies identified

Orthologs in non-Arthropod Metazoa (None identified)

No non-Arthropod Metazoa orthologies identified

Human Orthologs (0)

Gene

OMIM

HGNC

AAA Orthologs (0) based on analysis using Dmel annotation version 4.3

No orthologs identified

Stocks & Reagents

Stocks Listed in FlyBase ( 1 )

Bloomington

3799

tu(2)W^g

Genomic Clones ( 0 )

cDNA Clones ( 0 )

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

246938

Antibody Information

Other Information

Discoverer

Gowen.

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Other Comments

One of several loci at which mutations result in melanotic masses (tumors).

External Crossreferences & Linkouts

Sequence Crossreferences

Other Crossreferences

Linkouts

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

246938

Synonyms & Secondary IDs ( 3 )

Reported As

Symbol Synonym

tu(2)W

(Markovic et al., 2009)

tu-W

(Lavine and Strand, 2002, Dearolf, 1998, )

Name Synonym

tumor(2)W

Secondary FlyBase IDs

References ( 17 )

Research paper

Markovic et al., 2009, Molec. Immunol. 46(16): 3245--3250: Drosophila lamin mutations cause melanotic mass formation and lamellocyte differentiation. [FBrf0208951]
Rizki and Rizki, 1981, J. Hered. 72: 78--80: Genetics of tumor-W in Drosophila melanogaster: mapping a gene with incomplete penetrance. [FBrf0036859]
Rizki and Rizki, 1974, Experientia 30: 543--546: Basement membrane abnormalities in melanotic tumor formation of Drosophila. [FBrf0026284]
Rizki and Rizki, 1974, J. Invert. Path. 24: 37--40: Topology of the caudal fat body of the tumor-w mutant of Drosophila melanogaster. [FBrf0026603]
Sparrow, 1974, Genet. Res. (Camb.) 23: 13--21: The genetics of some second chromosome melanotic tumour mutants of Drosophila melanogaster. [FBrf0026309]
Burdette and Carver, 1970, D. I. S. 45: 151: Frequency of tumors in several laboratory stocks of Drosophila melanogaster. [FBrf0021304]
Bryant and Sang, 1969, Genetics 62: 321--336: Physiological genetics of melanotic tumors in Drosophila melanogaster. [FBrf0020563]
Bryant and Sang, 1968, Nature 220: 393--394: Drosophila: Lethal derangements of metamorphosis and modifications of gene expression caused by juvenile hormone mimics. [FBrf0019990]
Yamazaki and Ohnishi, 1968, Genetics 59: 237--243: Phenol oxidase activity and phenotypic expression of the melanotic tumor strain tu^g in Drosophila melanogaster. [FBrf0019602]
Burdette, 1959, Univ. Texas Publs 5914: 57--68: Tumors in Drosophila. [FBrf0012974]
Rizki, 1957, J. Morph. 100: 459--472: Tumor formation in relation to metamorphosis in Drosophila melanogaster. [FBrf0011468]
Wilson et al., 1955, Growth 19: 215--244: Studies on the TU^W strain of Drosophila melanogaster. [FBrf0010238]
Oftedal, 1953, Z. indukt. Abstamm.- u. VererbLehre 85: 408--422: The histogenesis of a new tumor in Drosophila melanogaster, and a comparison with tumors of five other stocks Z. indukt. [FBrf0009229]
Burdette, 1951, D. I. S. 25: 101--102: Incidence of tumors in different strains of Drosophila. [FBrf0008081]

Review

Lavine and Strand, 2002, Insect Biochem. Mol. Biol. 32(10): 1295--1309: Insect hemocytes and their role in immunity. [FBrf0155844]
Dearolf, 1998, Biochim. Biophys. Acta 1377(1): M13--M23: Fruit fly 'leukemia'. [FBrf0102303]

Book

Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster.: The Genome of Drosophila melanogaster. [FBrf0066905]