l(2)04820, DUb80, mfs48, Ubiquitin, Ubi-m
Please see the JBrowse view of Dmel\RpS27A for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
Shares 5' UTR with upstream gene.
Gene model reviewed during 5.45
0.9 (northern blot)
There is only one protein coding transcript and one polypeptide associated with this gene
156 (aa)
Ribosomal protein S27a is part of the 40S ribosomal subunit.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\RpS27A using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signals
View Dmel\RpS27A in GBrowse 22-42
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: RpS27A l(2)04820
"RpS27A" likely corresponds to "M(2)31E".
Likely Minute gene.
Deletions removing RpS27A but no other cytoplasmic ribosomal protein-encoding genes show Minute phenotypes.
The genomic organisation of the RpS27A locus has been characterised.
Antibody staining of polytene chromosomes shows that ubiquitin is mainly associated with the compact and stabilized structure that forms the bands rather than with the more decondensed and destabilized protein-DNA structure that forms interbands and puffs.
Four (unnamed) recessive lethal alleles have been isolated during a cytogenetic analysis of chromosomal region 31.
RpS27A expression has been studied in heat shocked aging flies.
Recessive alleles suppress position-effect variegation of In(1)wm4 when homozygous. The suppressor phenotypes are sexually dimorphic.
Structural gene for ubiquitin (Lee et al., 1988). Ubi-f80 codes for a fusion protein whose single ubiquitin sequence is attached to a tail polypeptide with 65% identity to the yeast ubiquitin tail protein and 82% identity to the human ubiquitin tail protein. Ubiquitin-monomeric is not inducible by heat shock.