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Gene Dmel\Ubx

General Information
Symbol	Dmel\Ubx	Species	D. melanogaster
Name	Ultrabithorax	Annotation symbol	CG10388
Feature type	protein_coding_gene	FlyBase ID	FBgn0003944
Gene Model Status	Current	Stock availability	250 publicly available
Also Known As	bx, pbx, Cbx, bxd, abx, BX-C, DmUbx, Ubx1b
Genomic Location
Chromosome (arm)	3R	Recombination map	3-58.8
Cytogenetic map	89D6-89D9	Sequence location	3R:12,482,345..12,560,348 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Ultrabithorax is referred to in FlyBase by the symbol Dmel\Ubx (CG10388, FBgn0003944). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; RNA polymerase II distal enhancer sequence-specific DNA binding; sequence-specific DNA binding; protein domain specific binding; DNA binding. There is experimental evidence for 13 unique biological process terms, many of which group under: anatomical structure development; biological regulation; organ development; regulation of cellular macromolecule biosynthetic process; regulation of biological process; regulation of multicellular organismal development; regulation of developmental process; organ morphogenesis; cell fate commitment; cell fate determination; segment specification. 481 alleles are reported. The phenotypes of these alleles are annotated with: organ system subdivision; adult segment; larval abdominal segment; adult mesothoracic segment; organ system; thoracic segment; hypodermal muscle of larval abdomen; primordium; A1-7 transverse muscle; sensillum. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Homeobox; Homeobox protein, antennapedia type, conserved site; Homeobox, conserved site; Homeobox, eukaryotic; Homeodomain-like; Homeodomain-related. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis, during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult thoracico-abdominal ganglion, adult spermathecae. Comments on Affy2 ProbeSet: ProbeSet 1633550_a_at completely aligns to an exonic region common to each of the 6 FlyBase-annotated transcript isoforms of Ubx. Gene sequence location is 3R:12482345..12560348.
External Summaries
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	abx: anterobithorax (E.B. Lewis) Homozygotes show variable tranformations of the anteriormost portion of the third thoracic segment (T3) toward the corresponding part of T2. Homozygotes also show variable tranformations of posterior T2 to posterior T1. The latter effect is enhanced by low temperature. Partially complements and shows transvection with bx1, bx3, and bx34e. abx/pbx has the posterior portion of the distal segment of the haltere very slightly transformed into wing tissue; abx/pbx2 is similar if heterozygous for a rearrangement that suppresses transvection. bx: bithorax (E.B. Lewis) bx: bithorax From Bridges and Morgan, 1923, Carnegie Inst. Washington Publ. No. 327: 152. Homozygote has anterior portion of third thoracic segment (T3) transformed toward corresponding region of second (T2). The extent of this transformation is allele dependent and is most extreme in bx3 and weakest in bx4. Although the transformations caused by most bx alleles are uniform, those caused by bx1 and bx34eprv are highly variable. At 17C several bx alleles show weak and variable transformations of posterior T2 to posterior T1. bx3, bx8, and bxG over pbx show a very slight pbx effect (as described for abx) if heterozygous for a rearrangement that suppresses transvection. bxd: bithoraxoid (E.B. Lewis) bxd: bithoraxoid From Bridges and Morgan, 1923, Carnegie Inst. Washington Publ. No. 327: 225. Homozygotes show transformation of the anterior first abdominal segment (A1) to the corresponding region of the third thoracic segment (T3). In addition, bxd homozygotes have posterior T3 and posterior A1 transformed toward posterior T2. Hemizygotes for the stronger bxd alleles show (with variable expression) formation of one or a pair of well-developed thoracic legs and, rarely, an extra haltere on A1; the frequency of these abdominal halteres is greatly enhanced in hemizygotes for bxd9 iab2K. The A1 legs in bxd hemizygotes contain underdeveloped posterior compartments, indicating that posterior A1 is partially transformed toward thorax. Cbx: Contrabithorax (E.B. Lewis) Cbx1/+ has a strong transformation of the posterior region of the second thoracic segment (T2) toward the corresponding region of the third (T3), and a weak and variable transformation of anterior T2 toward anterior T3. The Cbx1 homozygote differs in having a stronger, but still variable, transformation of anterior T2 toward T3. Cbx1/Ubx has a slight enhancement of the Ubx phenotype (see also su-Cbx). Cbx2 has both anterior and posterior regions of T2 moderately transformed toward T3. CbxHm affects only the wing, which is strongly transformed to haltere. Flies carrying two doses of CbxHm plus a normal allele have a virtually complete transformation of wing to haltere (as figured in Lewis, 1982). Cbx2 and CbxHm have inseparable recessive bxd effects. Cbx3/+ transforms anterior portions of T2 variably toward anterior T3. It has no effect in posterior T2. For an overview of the effects of Cbx mutants on specific structures see Table 1: Lewis, 1982. pbx: postbithorax Adult homozygotes and hemizygotes have posterior region of third thoracic segment (T3) transformed toward corresponding region of the second (T2). Uab: Ultraabdominal (E.B. Lewis) Uab1, Uab2, and Uab4 cause A1 to transform toward A2. Uab5 causes A1 and A2 to transform toward A3. Uab1 is an intra-complex inversion with a breakpoint in the bxd region, Uab2 is associated with a Uab mutation, the Uab4 breakpoint is an iab-3 mutation, and the Uab5 breakpoint is a weak bxd mutation. Reversion studies show that Uab1, Uab4, and Uab5 cause abnormal expression of abd-A domain functions in A1. Ubx: Ultrabithorax (E.B. Lewis) Larvae homozygous and hemizygous for strong Ubx mutants, such as the Ubx1-type, have the ventral setal bands or "hooklets" of the first abdominal segment (A1) and T3 transformed toward those of T2; dorsally, the hair patterns of posterior T2 and posterior T3 are transformed toward posterior T1; Keilin organs with 2 hairs appear on A1; ventral pits appear on segments A1 thru A7; two extra sets of anterior spiracles appear, one on T3 and one on A1. Homozygotes die, usually as tiny third-instar larvae, but occasionally grow to a normal-sized third-instar larvae and may pupate. Homozygotes of some weaker alleles, such as Ubx61d, survive to adult stage and show weak bx, bxd, and pbx effects, especially in the haltere, and A1 is generally reduced.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	References Kazemian et al., 2010, PLoS Biol. 8(8): Herz et al., 2010, Mol. Cell. Biol. 30(10): 2485--2497 Richter et al., 2011, Nat. Cell Biol. 13(9): 1029--1039 Tchurikov et al., 2011, Nucleic Acids Res. 39(9): 3667--3685 Starr et al., 2011, Dev. Biol. 359(2): 290--302 Tripura et al., 2011, Int. J. Dev. Biol. 55(6): 583--590 Tchuraev and Galimzyanov, 2009, J. Theor. Biol. 259(4): 659--669 Mace et al., 2010, Bioinformatics 26(6): 761--769 Hudry et al., 2011, BMC Biol. 9: 5 Controlled Vocabulary Terms negative regulation of transcription from RNA polymerase II promoter RNA polymerase II distal enhancer sequence-specific DNA binding Sequence features BKN31457 HFA16891
FB2011_10	References Liu et al., 2008, J. Biol. Chem. 283(30): 20874--20887 Knowles-Barley, 2011.8.24, BrainTrap expression curation. Chopra et al., 2008, Dev. Biol. 317(2): 660--670 Grad et al., 2004, Bioinformatics 20(16): 2738--2750 Majithia et al., 2011, Biomacromolecules 12(10): 3629--3637 Uhl et al., 2010, Dev. Biol. 343(1-2): 154--166 Margueron et al., 2009, Nature 461(7265): 762--767 Marco et al., 2009, Bioinformatics 25(19): 2473--2477
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 89D6-89D9   Limits computationally determined from genome sequence between P{lacW}CSN5L4032 and P{EP}MESK4EP1015
Experimentally Determined Cytological Location
Cytogenetic map Notes References 89E1-89E2   (determined by in situ hybridisation)   (Ranz et al., 1997) 89E1-89E2   (determined by in situ hybridisation)   (Qian et al., 1991) 89E1-89E2   (determined by in situ hybridisation)   (Thali et al., 1988) 89E-89E   (determined by in situ hybridisation)   (Akam, 1983)   Ubx is a component of the Bithorax complex.   (Martin et al., 1995)
Experimentally Determined Recombination Data
Location	3-58.8
Left of (cM)	Abd-B (Kuhn et al., 1984) Sgs9 (Hoshizaki et al., 1987)
Right of (cM)
Notes	Ubxbx-8 maps 0.0018 map units distal to Ubxbx-34e. (Babu et al., 1987)
Gene Model & Products
Please see the GBrowse view of Dmel\Ubx for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.41
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Ubx-RA FBtr0083347  NM_080504   4482   389 Ubx-RB FBtr0083348  NM_080500   3828   346 Ubx-RC FBtr0083349  NM_169730   4431   372 Ubx-RD FBtr0083350  NM_169728   2984   363 Ubx-RE FBtr0083351  NM_169729   3317   380 Ubx-RF FBtr0083352  NM_206497   4380   355
Additional Transcript Data & Comments
Reported size (kB)	4.3, 3.2 (northern blot) (Rowe and Akam, 1988)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Ubx-PA   FBpp0082793   40.0   389   9.07     NP_536752   AAF55355 Ubx-PB   FBpp0082794   35.4   346   9.55     NP_536748   AAF55356 Ubx-PC   FBpp0082795   38.2   372   9.09     NP_732173   AAN13719 Ubx-PD   FBpp0082796   37.2   363   9.52     NP_732171   AAN13717 Ubx-PE   FBpp0082797   39.1   380   9.49     NP_732172   AAN13718 Ubx-PF   FBpp0089155   36.3   355   9.11     NP_996219   AAS65158
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments	Gel-shift analysis shows specific binding of Ubx protein to fragments from the Pc gene region. (Chan et al., 1994)
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Homeobox, conserved site (IPR017970) Homeobox (IPR001356) Homeobox protein, antennapedia type, conserved site (IPR001827) Homeodomain-like (IPR009057) Homeodomain-related (IPR012287) Homeobox, eukaryotic (IPR020479) PDB - Protein Data Bank. An information portal to biological macromolecular structures • 1B8I
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF55355   AE014297 AAF55356   AE014297 AAN13717   AE014297 AAN13718   AE014297 AAN13719   AE014297 AAS65158   AI516075   BI357303   BI362075   BI578023   BP553092   BP556359   BT010241 AAQ23559   BT125062   CK658289   CO179010   CO186487   CO190745   CO262084   CO262698   CO272734   CO275373   CO281006   CO281387   CO286782   CO290043   CO296509   CO297719   CO315069   CO323008   CO331592   CO339204   CO339498   CZ471499   CZ471573   CZ489950   CZ489951   EC057363   EC057364   EC059148   EC059851   EC073122   EC085593   EC087188   EC196645   EC205165   EC209244   EC210775   EC217449   EC218331   EC218715   EC219396   EC221926   EC229591   EC230741   EC237517   EC242544   EC244033   EC246544   EC250459   EC253187   EC258935   EC260006   EC265391   GH951001   GH955348   GH957759   GH958203   GH968678   GH969786   GH971829   GH972285   GH978307   GH978315   K01959 AAA28615   K01963 AAA29008   L32205   L32750   L48177   M23335   M23336   M23337   M24609   U31961 AAA84408   U31961 AAA84409   U31961 AAA84410   U31961 AAA84411   U31961 AAA84412   X05427 CAA29008   X05427 CAA29009   X05723 CAA29194   X05724 CAA29194   X05725 CAA29194   X05726   X05727 CAA29194   X67586   X76210 CAA53803
UniProtKB/Swiss-Prot	P83949
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References protein binding site FBsf0000160205 3R:12,527,016..12,527,028 bound_moiety=ftz-XP evidence=experimental (Qian et al., 1993, Bergman et al., 2004) protein binding site FBsf0000160276 3R:12,527,089..12,527,106 bound_moiety=tll-XP evidence=experimental (Qian et al., 1993, Bergman et al., 2004) protein binding site FBsf0000160277 3R:12,599,841..12,599,849 bound_moiety=kni-XP evidence=experimental (Bergman et al., 2004, Zhang et al., 1991) protein binding site FBsf0000160278 3R:12,590,088..12,590,103 bound_moiety=z-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160279 3R:12,560,212..12,560,230 bound_moiety=z-XP evidence=experimental (Bergman et al., 2004, Biggin et al., 1988) protein binding site FBsf0000160280 3R:12,599,161..12,599,179 bound_moiety=ftz-XP evidence=experimental (Bergman et al., 2004, Pirrotta et al., 1995) protein binding site FBsf0000160281 3R:12,590,374..12,590,398 bound_moiety=z-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160282 3R:12,590,026..12,590,042 evidence=experimental bound_moiety=pho-XP (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160283 3R:12,560,246..12,560,260 bound_moiety=z-XP evidence=experimental (Bergman et al., 2004, Biggin et al., 1988) protein binding site FBsf0000160284 3R:12,599,313..12,599,325 bound_moiety=ftz-XP evidence=experimental (Bergman et al., 2004, Muller and Bienz, 1992) protein binding site FBsf0000160285 3R:12,526,648..12,526,665 bound_moiety=hb-XP evidence=experimental (Qian et al., 1993, Bergman et al., 2004) protein binding site FBsf0000160286 3R:12,589,546..12,589,563 bound_moiety=hb-XP evidence=experimental (Bergman et al., 2004, Mahmoudi et al., 2003) protein binding site FBsf0000160287 3R:12,560,061..12,560,108 bound_moiety=Ubx-XP evidence=experimental (Beachy et al., 1988, Bergman et al., 2004) protein binding site FBsf0000160288 3R:12,589,906..12,589,918 bound_moiety=Trl-XP evidence=experimental (Bergman et al., 2004, Mahmoudi et al., 2003) protein binding site FBsf0000160289 3R:12,590,301..12,590,332 bound_moiety=z-XP evidence=experimental (Bergman et al., 2004, Mahmoudi et al., 2003) protein binding site FBsf0000160290 3R:12,560,269..12,560,283 bound_moiety=z-XP evidence=experimental (Biggin et al., 1988, Bergman et al., 2004) protein binding site FBsf0000160291 3R:12,527,019..12,527,037 bound_moiety=twi-XP evidence=experimental (Bergman et al., 2004, Qian et al., 1993) protein binding site FBsf0000160292 3R:12,481,511..12,481,516 bound_moiety=z-XP evidence=experimental (Benson and Pirrotta, 1988, Bergman et al., 2004) protein binding site FBsf0000160293 3R:12,590,719..12,590,752 bound_moiety=Trl-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160294 3R:12,526,900..12,526,909 bound_moiety=twi-XP evidence=experimental (Qian et al., 1993, Bergman et al., 2004) protein binding site FBsf0000160295 3R:12,599,167..12,599,180 bound_moiety=en-XP evidence=experimental (Pirrotta et al., 1995, Bergman et al., 2004) protein binding site FBsf0000160296 3R:12,560,330..12,560,344 bound_moiety=Trl-XP evidence=experimental (Biggin and Tjian, 1988, Bergman et al., 2004) protein binding site FBsf0000160297 3R:12,526,804..12,526,815 bound_moiety=en-XP evidence=experimental (Bergman et al., 2004, Qian et al., 1993) protein binding site FBsf0000160298 3R:12,599,333..12,599,346 bound_moiety=ftz-XP evidence=experimental (Muller and Bienz, 1992, Bergman et al., 2004) protein binding site FBsf0000160299 3R:12,590,108..12,590,125 bound_moiety=z-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160300 3R:12,590,056..12,590,072 bound_moiety=Trl-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160301 3R:12,589,921..12,589,943 bound_moiety=pho-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160302 3R:12,589,585..12,589,605 bound_moiety=Trl-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160303 3R:12,599,333..12,599,351 bound_moiety=kni-XP evidence=experimental (Bergman et al., 2004, Zhang et al., 1991) protein binding site FBsf0000160304 3R:12,590,251..12,590,278 bound_moiety=hb-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160305 3R:12,599,326..12,599,345 bound_moiety=en-XP evidence=experimental (Bergman et al., 2004, Pirrotta et al., 1995) protein binding site FBsf0000160306 3R:12,562,948..12,562,960 evidence=experimental (Eresh et al., 1997, Bergman et al., 2004) protein binding site FBsf0000160178 3R:12,560,253..12,560,271 evidence=experimental (Bergman et al., 2004, Biggin and Tjian, 1988) protein binding site FBsf0000160179 3R:12,560,027..12,560,046 evidence=experimental (Biggin and Tjian, 1988, Bergman et al., 2004) protein binding site FBsf0000160180 3R:12,527,001..12,527,023 bound_moiety=hb-XP evidence=experimental (Qian et al., 1991, Bergman et al., 2004) protein binding site FBsf0000160181 3R:12,562,924..12,562,942 evidence=experimental (Eresh et al., 1997, Bergman et al., 2004) protein binding site FBsf0000160182 3R:12,526,966..12,526,992 bound_moiety=tll-XP evidence=experimental (Qian et al., 1993, Bergman et al., 2004) protein binding site FBsf0000160183 3R:12,599,167..12,599,184 bound_moiety=hb-XP evidence=experimental (Zhang et al., 1991, Bergman et al., 2004) protein binding site FBsf0000160184 3R:12,599,116..12,599,134 bound_moiety=twi-XP evidence=experimental (Pirrotta et al., 1995, Bergman et al., 2004) protein binding site FBsf0000160192 3R:12,589,580..12,589,595 bound_moiety=hb-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160193 3R:12,560,289..12,560,304 bound_moiety=z-XP evidence=experimental (Bergman et al., 2004, Biggin et al., 1988) protein binding site FBsf0000160194 3R:12,589,526..12,589,545 bound_moiety=Trl-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160195 3R:12,600,037..12,600,045 bound_moiety=kni-XP evidence=experimental (Zhang et al., 1991, Bergman et al., 2004) protein binding site FBsf0000160196 3R:12,589,860..12,589,903 bound_moiety=Trl-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160197 3R:12,526,987..12,527,005 bound_moiety=twi-XP evidence=experimental (Bergman et al., 2004, Qian et al., 1993) protein binding site FBsf0000160198 3R:12,590,048..12,590,066 bound_moiety=pho-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160199 3R:12,560,254..12,560,269 bound_moiety=grh-XP evidence=experimental (Dynlacht et al., 1989, Bergman et al., 2004) protein binding site FBsf0000160200 3R:12,599,408..12,599,419 bound_moiety=ftz-XP evidence=experimental (Bergman et al., 2004, Muller and Bienz, 1992) protein binding site FBsf0000160233 3R:12,559,840..12,559,931 bound_moiety=Ubx-XP evidence=experimental (Beachy et al., 1988, Bergman et al., 2004) protein binding site FBsf0000160234 3R:12,590,579..12,590,598 bound_moiety=z-XP evidence=experimental (Bergman et al., 2004, Mahmoudi et al., 2003) protein binding site FBsf0000160235 3R:12,599,101..12,599,116 bound_moiety=hb-XP evidence=experimental (Zhang et al., 1991, Bergman et al., 2004) protein binding site FBsf0000160236 3R:12,562,864..12,562,893 bound_moiety=shn-XP evidence=experimental (Dai et al., 2000, Bergman et al., 2004) protein binding site FBsf0000159759 3R:12,590,429..12,590,450 bound_moiety=hb-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000159760 3R:12,560,184..12,560,204 bound_moiety=Trl-XP evidence=experimental (Biggin and Tjian, 1988, Bergman et al., 2004) protein binding site FBsf0000159761 3R:12,589,741..12,589,759 bound_moiety=z-XP evidence=experimental (Bergman et al., 2004, Mahmoudi et al., 2003) protein binding site FBsf0000160237 3R:12,590,075..12,590,104 bound_moiety=hb-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160307 3R:12,590,893..12,590,911 bound_moiety=hb-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160308 3R:12,589,873..12,589,890 bound_moiety=z-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160309 3R:12,590,281..12,590,304 bound_moiety=hb-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160310 3R:12,590,519..12,590,537 bound_moiety=hb-XP evidence=experimental (Bergman et al., 2004, Mahmoudi et al., 2003) protein binding site FBsf0000160311 3R:12,562,813..12,562,827 bound_moiety=shn-XP evidence=experimental (Dai et al., 2000, Bergman et al., 2004) protein binding site FBsf0000160312 3R:12,599,231..12,599,258 bound_moiety=ftz-XP evidence=experimental (Bergman et al., 2004, Muller and Bienz, 1992) protein binding site FBsf0000160313 3R:12,589,608..12,589,618 bound_moiety=Trl-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160314 3R:12,590,460..12,590,481 bound_moiety=hb-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160315 3R:12,589,608..12,589,624 bound_moiety=z-XP evidence=experimental (Bergman et al., 2004, Mahmoudi et al., 2003) protein binding site FBsf0000160316 3R:12,559,847..12,559,932 bound_moiety=eve-XP bound_moiety=zen-XP evidence=experimental (Bergman et al., 2004, Biggin and Tjian, 1989) protein binding site FBsf0000160317 3R:12,599,383..12,599,398 bound_moiety=hb-XP evidence=experimental (Bergman et al., 2004, Zhang et al., 1991) protein binding site FBsf0000160318 3R:12,526,988..12,526,997 bound_moiety=en-XP evidence=experimental (Qian et al., 1993, Bergman et al., 2004) protein binding site FBsf0000160319 3R:12,526,730..12,526,748 bound_moiety=twi-XP evidence=experimental (Qian et al., 1993, Bergman et al., 2004) protein binding site FBsf0000160320 3R:12,599,153..12,599,172 bound_moiety=twi-XP evidence=experimental (Pirrotta et al., 1995, Bergman et al., 2004) protein binding site FBsf0000160321 3R:12,599,144..12,599,157 bound_moiety=tll-XP evidence=experimental (Pirrotta et al., 1995, Bergman et al., 2004) protein binding site FBsf0000160322 3R:12,590,382..12,590,403 evidence=experimental bound_moiety=hb-XP (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160323 3R:12,590,484..12,590,502 bound_moiety=hb-XP evidence=experimental (Bergman et al., 2004, Mahmoudi et al., 2003) protein binding site FBsf0000160324 3R:12,589,768..12,589,907 bound_moiety=pho-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160325 3R:12,589,954..12,589,974 bound_moiety=z-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160326 3R:12,599,303..12,599,336 bound_moiety=hb-XP evidence=experimental (Bergman et al., 2004, Zhang et al., 1991) protein binding site FBsf0000160327 3R:12,590,698..12,590,722 bound_moiety=hb-XP evidence=experimental (Bergman et al., 2004, Mahmoudi et al., 2003) protein binding site FBsf0000160328 3R:12,590,084..12,590,099 bound_moiety=pho-XP evidence=experimental (Bergman et al., 2004, Mahmoudi et al., 2003) protein binding site FBsf0000160329 3R:12,589,644..12,589,664 bound_moiety=hb-XP evidence=experimental (Bergman et al., 2004, Mahmoudi et al., 2003) protein binding site FBsf0000160330 3R:12,598,893..12,598,901 bound_moiety=kni-XP evidence=experimental (Zhang et al., 1991, Bergman et al., 2004) protein binding site FBsf0000160331 3R:12,590,862..12,590,884 bound_moiety=hb-XP evidence=experimental (Bergman et al., 2004, Mahmoudi et al., 2003) protein binding site FBsf0000160332 3R:12,590,594..12,590,642 bound_moiety=hb-XP evidence=experimental (Bergman et al., 2004, Mahmoudi et al., 2003) protein binding site FBsf0000160333 3R:12,589,559..12,589,578 bound_moiety=Trl-XP evidence=experimental (Bergman et al., 2004, Mahmoudi et al., 2003) protein binding site FBsf0000160334 3R:12,589,999..12,590,016 bound_moiety=z-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160335 3R:12,590,367..12,590,393 bound_moiety=Trl-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160336 3R:12,526,853..12,526,902 bound_moiety=ftz-XP evidence=experimental (Bergman et al., 2004, Qian et al., 1993) protein binding site FBsf0000160337 3R:12,590,409..12,590,438 bound_moiety=z-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160338 3R:12,599,130..12,599,142 bound_moiety=hb-XP evidence=experimental (Zhang et al., 1991, Bergman et al., 2004) protein binding site FBsf0000160339 3R:12,589,719..12,589,737 bound_moiety=z-XP evidence=experimental (Bergman et al., 2004, Mahmoudi et al., 2003) protein binding site FBsf0000160340 3R:12,590,699..12,590,727 bound_moiety=z-XP evidence=experimental (Bergman et al., 2004, Mahmoudi et al., 2003) protein binding site FBsf0000160341 3R:12,599,286..12,599,303 bound_moiety=tll-XP evidence=experimental (Bergman et al., 2004, Pirrotta et al., 1995) protein binding site FBsf0000160342 3R:12,589,950..12,589,973 bound_moiety=Trl-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160343 3R:12,598,980..12,598,989 bound_moiety=Kr-XP evidence=experimental (Zhang et al., 1991, Bergman et al., 2004) protein binding site FBsf0000160344 3R:12,590,784..12,590,808 bound_moiety=hb-XP evidence=experimental (Bergman et al., 2004, Mahmoudi et al., 2003) protein binding site FBsf0000160345 3R:12,526,956..12,527,000 bound_moiety=ftz-XP evidence=experimental (Qian et al., 1993, Bergman et al., 2004) protein binding site FBsf0000160346 3R:12,481,458..12,481,463 bound_moiety=z-XP evidence=experimental (Benson and Pirrotta, 1988, Bergman et al., 2004) protein binding site FBsf0000160347 3R:12,599,235..12,599,253 bound_moiety=en-XP evidence=experimental (Bergman et al., 2004, Pirrotta et al., 1995) protein binding site FBsf0000160348 3R:12,526,870..12,526,902 bound_moiety=hb-XP evidence=experimental (Bergman et al., 2004, Qian et al., 1993) protein binding site FBsf0000160349 3R:12,589,443..12,589,467 bound_moiety=z-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160350 3R:12,527,040..12,527,064 bound_moiety=hb-XP evidence=experimental (Qian et al., 1991, Bergman et al., 2004) protein binding site FBsf0000160351 3R:12,560,114..12,560,134 evidence=experimental (Biggin and Tjian, 1988, Bergman et al., 2004) protein binding site FBsf0000160352 3R:12,589,983..12,590,005 bound_moiety=Trl-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160353 3R:12,527,038..12,527,047 bound_moiety=ftz-XP evidence=experimental (Bergman et al., 2004, Qian et al., 1993) protein binding site FBsf0000160354 3R:12,560,232..12,560,247 bound_moiety=Trl-XP evidence=experimental (Bergman et al., 2004, Biggin and Tjian, 1988) protein binding site FBsf0000160355 3R:12,560,189..12,560,204 bound_moiety=z-XP evidence=experimental (Biggin et al., 1988, Bergman et al., 2004) protein binding site FBsf0000160356 3R:12,599,053..12,599,067 bound_moiety=hb-XP evidence=experimental (Zhang et al., 1991, Bergman et al., 2004) protein binding site FBsf0000160357 3R:12,598,704..12,598,712 bound_moiety=kni-XP evidence=experimental (Zhang et al., 1991, Bergman et al., 2004) protein binding site FBsf0000160358 3R:12,589,995..12,590,012 bound_moiety=hb-XP evidence=experimental (Bergman et al., 2004, Mahmoudi et al., 2003) protein binding site FBsf0000160359 3R:12,589,700..12,589,726 bound_moiety=Trl-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160360 3R:12,560,279..12,560,296 bound_moiety=Trl-XP evidence=experimental (Bergman et al., 2004, Biggin and Tjian, 1988) protein binding site FBsf0000160361 3R:12,526,878..12,526,902 bound_moiety=tll-XP evidence=experimental (Qian et al., 1993, Bergman et al., 2004) protein binding site FBsf0000160362 3R:12,590,730..12,590,750 bound_moiety=z-XP evidence=experimental (Bergman et al., 2004, Mahmoudi et al., 2003) protein binding site FBsf0000160363 3R:12,481,491..12,481,500 bound_moiety=z-XP evidence=experimental (Bergman et al., 2004, Benson and Pirrotta, 1988) protein binding site FBsf0000160364 3R:12,599,438..12,599,454 bound_moiety=ftz-XP evidence=experimental (Muller and Bienz, 1992, Bergman et al., 2004) protein binding site FBsf0000160365 3R:12,589,730..12,589,762 bound_moiety=Trl-XP evidence=experimental (Mahmoudi et al., 2003, Bergman et al., 2004) protein binding site FBsf0000160366 3R:12,560,060..12,560,106 bound_moiety=zen-XP bound_moiety=eve-XP evidence=experimental (Biggin and Tjian, 1989, Bergman et al., 2004, Biggin and Tjian, 1988)
External Data
Linkouts
Crossreferences	EPD - Eukarytoic Promoter Database, an annotated collection of POL II promoters • 17017
Expression Data
Transcript Expression
No Assay Recorded Stage Tissue/Position (including subcellular localization) Reference embryonic stage     (Roder et al., 1992) visceral mesoderm   (Artero et al., 1992) in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage     (Fasano et al., 1991) parasegment 6 of presumptive embryonic/larval central nervous system   (Artero et al., 1992) presumptive embryonic/larval central nervous system   (Artero et al., 1992) somatic mesoderm   (Artero et al., 1992) embryonic stage | late   parasegment 6 of presumptive embryonic/larval central nervous system   (Artero et al., 1992) embryonic stage 6   organism | restricted   (Zhang et al., 1991) Comment:broad central band northern blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 17     (Rowe and Akam, 1988) embryonic stage 11 -- 17     (Rowe and Akam, 1988) embryonic stage 12   parasegment 5 -- parasegment 13   (Rowe and Akam, 1988)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
No Assay Recorded Stage Tissue/Position (including subcellular localization) Reference embryonic stage   visceral mesoderm   (Tremml and Bienz, 1989)   (Macias et al., 1990) embryonic stage 11 -- 13   visceral mesoderm   (Thuringer and Bienz, 1993) immunolocalization Stage Tissue/Position (including subcellular localization) Reference embryonic stage | late   embryonic dorsal vessel | central   (Lo et al., 2002) cardioblast & embryonic pericardial cell of embryonic abdominal segment 2 -- embryonic abdominal segment 5   (Lo et al., 2002) embryonic stage 11   parasegment 5 -- parasegment 13   (Gebelein et al., 2002) embryonic stage 11 -- 16   parasegment 5 -- parasegment 13   (Birve et al., 2001) embryonic stage 12   parasegment 7 of visceral mesoderm   (Chan et al., 1994) embryonic stage 13 -- 14   visceral mesoderm of embryonic/larval midgut of parasegment 7   (Tremml and Bienz, 1989) embryonic stage 14   parasegment 7 of visceral mesoderm   (Immergluck et al., 1990) visceral mesoderm   • nucleus (Immergluck et al., 1990) embryonic metathoracic neuromere   • nucleus (Celniker et al., 1989) embryonic abdominal 1 neuromere   • nucleus (Celniker et al., 1989) embryonic abdominal 2 neuromere   • nucleus (Celniker et al., 1989) embryonic abdominal 3 neuromere   • nucleus (Celniker et al., 1989) embryonic abdominal 4 neuromere   • nucleus (Celniker et al., 1989) embryonic abdominal 5 neuromere   • nucleus (Celniker et al., 1989) embryonic abdominal 6 neuromere   • nucleus (Celniker et al., 1989) embryonic abdominal 7 neuromere   • nucleus (Celniker et al., 1989) embryonic stage 15 -- 16   parasegment 5 -- parasegment 13 of embryonic ventral nervous system | segmentally repeated   (Struhl and White, 1985) embryonic stage 16   embryonic/larval dorsal vessel | faint   (Lovato et al., 2002) Comment:from A2 through posterior tip of heart mesoderm   (Lovato et al., 2002) ventral midline of parasegment 14 | restricted   (Birve et al., 2001) Comment:5 midline cells embryonic stage 16 -- 17   parasegment 5 -- parasegment 14   (Gonzalez-Reyes and Morata, 1990) embryonic stage 17   embryonic mesothoracic segment & embryonic metathoracic segment   (Galant et al., 2002) Comment:expressed from mesothoracic segment to abdominal segment 5 embryonic abdominal segment 1 -- embryonic abdominal segment 5   (Galant et al., 2002) Comment:expressed from mesothoracic segment to abdominal segment 5 larval stage   embryonic/larval fat body | central   • polytene chromosome band | subset (Marchetti et al., 2003)
Additional Descriptive Data
	In wghs.P embryos, after heat shock, Ubx protein is only seen in those cells that do not express en. This is a similar expression pattern to that found in nkd mutant embryos. (Noordermeer et al., 1992) In abd-A- embryos, Ubx protein levels are higher than in wild type embryos in posterior compartments of metameres of the abd-A domain suggesting that abd-A downregulates Ubx in these domains. (Macias et al., 1990) Protein is detected in the midsection of the embryonic dorsal vessel. The protein is expressed in cardioblasts of abdominal segments A2-A5. Low level expression of Ubx is also observed in pericardial cells of these segments. The cardiac segment of the dorsal vessel contains barely detectable levels of Ubx protein. (Lo et al., 2002) Ubx protein is expressed at low levels in all cells of the dorsal vessel between abdominal segment 2 and the posterior tip of the embryonic heart. (Lovato et al., 2002) The posterior dpp stripe coincides with Ubx expression in parasegment 7. Ubx expression is unaffected in dpps4 embryos. (Immergluck et al., 1990) Ubiquitously expressed wg leads to the anterior expansion of the domain of Ubx expression in the visceral mesoderm to encompass parasegments 6 and 7. Ubiquitous dpp has no effect on the domain of Ubx expression. (Thuringer and Bienz, 1993) Antp protein is first detected at germ band retraction stage in a 6-7 cell width stripe in the midgut visceral mesoderm and the ectoderm of parasegment 7. (Tremml and Bienz, 1989) Mutations in the shv region of dpp cause a range of effects on Ubx expression. Generally, the Ubx expression domain is narrowed or the Ubx protein level is reduced. abd-A mutations cause expansion of the domain of Ubx expression in the visceral mesoderm to include the entire posterior midgut. (Panganiban et al., 1990) The Ubx expression domain is twice as wide in homozygous ftz mutant embryos as in wild type. Embryos homozygous for eve3 showed no Ubx staining but there is some staining in embryos homozygous for eve4. Normal homeotic gene function is seen in embryos homozygous for en59, en54, en55, wgl-17, opa1, h41, odd5, prd4 and runB102. No Ubx gene expression is seen in ftz,prd double mutant embryos, some staining is seen in opa,prd double mutant embryos and there is normal staining in odd,eve double mutant embryos. The Ubx domain is in the right position in KrB206 mutants, shifted posteriorly in kni mutants and shifted anteriorly in hb mutants. (Tremml and Bienz, 1989) The Ubx protein is expressed in the nuclei of larval fat body cells with an anterior boundary of around T3 and a posterior limit near A6/A7. Expression occurs in all nuclei of this region and specific labeling of polytene chromosome bands can be mapped. (Marchetti et al., 2003)
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0003944    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0003944 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis, during early pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0003944 expression level Developmental Stage   Expression Level embryo 00-02hr    17 embryo 02-04hr    153 embryo 04-06hr    543 embryo 06-08hr    1258 embryo 08-10hr    1084 embryo 10-12hr    941 embryo 12-14hr    1050 embryo 14-16hr    609 embryo 16-18hr    629 embryo 18-20hr    501 embryo 20-22hr    314 embryo 22-24hr    395 larva L1    233 larva L2    143 larva L3 12hr old    100 larva L3 puffstage 1-2    87 larva L3 puffstage 3-6    237 larva L3 puffstage 7-9    388 white prepupae new    457 white prepupae 12hr    236 white prepupae 24hr    350 pupae 2d postWPP    194 pupae 3d postWPP    78 pupae 4d postWPP    56 adult male 01day    122 adult male 05day    115 adult male 30day    60 adult female 01day    68 adult female 05day    35 adult female 30day    39 Expression Level Scale  None   Extremely low   Very low   Low   Moderate  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    17 embryo 02-04hr  (153) embryo 04-06hr  (543) embryo 06-08hr  (1258) embryo 08-10hr  (1084) embryo 10-12hr  (941) embryo 12-14hr  (1050) embryo 14-16hr  (609) embryo 16-18hr  (629) embryo 18-20hr  (501) embryo 20-22hr  (314) embryo 22-24hr  (395) larva L1  (233) larva L2  (143) larva L3 12hr old    100 larva L3 puffstage 1-2    87 larva L3 puffstage 3-6  (237) larva L3 puffstage 7-9  (388) white prepupae new  (457) white prepupae 12hr  (236) white prepupae 24hr  (350) pupae 2d postWPP  (194) pupae 3d postWPP    78 pupae 4d postWPP    56 adult male 01day  (122) adult male 05day  (115) adult male 30day    60 adult female 01day    68 adult female 05day    35 adult female 30day    39 Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    17 embryo 02-04hr    153 embryo 04-06hr    543 embryo 06-08hr    1258 embryo 08-10hr    1084 embryo 10-12hr    941 embryo 12-14hr    1050 embryo 14-16hr    609 embryo 16-18hr    629 embryo 18-20hr    501 embryo 20-22hr    314 embryo 22-24hr    395 larva L1    233 larva L2    143 larva L3 12hr old    100 larva L3 puffstage 1-2    87 larva L3 puffstage 3-6    237 larva L3 puffstage 7-9    388 white prepupae new    457 white prepupae 12hr    236 white prepupae 24hr    350 pupae 2d postWPP    194 pupae 3d postWPP    78 pupae 4d postWPP    56 adult male 01day    122 adult male 05day    115 adult male 30day    60 adult female 01day    68 adult female 05day    35 adult female 30day    39 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    17 embryo 02-04hr    153 embryo 04-06hr    543 embryo 06-08hr    1258 embryo 08-10hr    1084 embryo 10-12hr    941 embryo 12-14hr    1050 embryo 14-16hr    609 embryo 16-18hr    629 embryo 18-20hr    501 embryo 20-22hr    314 embryo 22-24hr    395 larva L1    233 larva L2    143 larva L3 12hr old    100 larva L3 puffstage 1-2    87 larva L3 puffstage 3-6    237 larva L3 puffstage 7-9    388 white prepupae new    457 white prepupae 12hr    236 white prepupae 24hr    350 pupae 2d postWPP    194 pupae 3d postWPP    78 pupae 4d postWPP    56 adult male 01day    122 adult male 05day    115 adult male 30day    60 adult female 01day    68 adult female 05day    35 adult female 30day    39 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    17 embryo 02-04hr    153 embryo 04-06hr    543 embryo 06-08hr    1258 embryo 08-10hr    1084 embryo 10-12hr    941 embryo 12-14hr    1050 embryo 14-16hr    609 embryo 16-18hr    629 embryo 18-20hr    501 embryo 20-22hr    314 embryo 22-24hr    395 larva L1    233 larva L2    143 larva L3 12hr old    100 larva L3 puffstage 1-2    87 larva L3 puffstage 3-6    237 larva L3 puffstage 7-9    388 white prepupae new    457 white prepupae 12hr    236 white prepupae 24hr    350 pupae 2d postWPP    194 pupae 3d postWPP    78 pupae 4d postWPP    56 adult male 01day    122 adult male 05day    115 adult male 30day    60 adult female 01day    68 adult female 05day    35 adult female 30day    39 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0003944 expression level Developmental Stage   Expression Level embryo 00-02hr    17 embryo 02-04hr    153 embryo 04-06hr    543 embryo 06-08hr    1258 embryo 08-10hr    1084 embryo 10-12hr    941 embryo 12-14hr    1050 embryo 14-16hr    609 embryo 16-18hr    629 embryo 18-20hr    501 embryo 20-22hr    314 embryo 22-24hr    395 larva L1    233 larva L2    143 larva L3 12hr old    100 larva L3 puffstage 1-2    87 larva L3 puffstage 3-6    237 larva L3 puffstage 7-9    388 white prepupae new    457 white prepupae 12hr    236 white prepupae 24hr    350 pupae 2d postWPP    194 pupae 3d postWPP    78 pupae 4d postWPP    56 adult male 01day    122 adult male 05day    115 adult male 30day    60 adult female 01day    68 adult female 05day    35 adult female 30day    39 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    17 embryo 02-04hr  (153) embryo 04-06hr  (543) embryo 06-08hr  (1258) embryo 08-10hr  (1084) embryo 10-12hr  (941) embryo 12-14hr  (1050) embryo 14-16hr  (609) embryo 16-18hr  (629) embryo 18-20hr  (501) embryo 20-22hr  (314) embryo 22-24hr  (395) larva L1  (233) larva L2  143 larva L3 12hr old    100 larva L3 puffstage 1-2    87 larva L3 puffstage 3-6  (237) larva L3 puffstage 7-9  (388) white prepupae new  (457) white prepupae 12hr  (236) white prepupae 24hr  (350) pupae 2d postWPP  (194) pupae 3d postWPP    78 pupae 4d postWPP    56 adult male 01day  122 adult male 05day  115 adult male 30day    60 adult female 01day    68 adult female 05day    35 adult female 30day    39 Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    17 embryo 02-04hr    153 embryo 04-06hr    543 embryo 06-08hr    1258 embryo 08-10hr    1084 embryo 10-12hr    941 embryo 12-14hr    1050 embryo 14-16hr    609 embryo 16-18hr    629 embryo 18-20hr    501 embryo 20-22hr    314 embryo 22-24hr    395 larva L1    233 larva L2    143 larva L3 12hr old    100 larva L3 puffstage 1-2    87 larva L3 puffstage 3-6    237 larva L3 puffstage 7-9    388 white prepupae new    457 white prepupae 12hr    236 white prepupae 24hr    350 pupae 2d postWPP    194 pupae 3d postWPP    78 pupae 4d postWPP    56 adult male 01day    122 adult male 05day    115 adult male 30day    60 adult female 01day    68 adult female 05day    35 adult female 30day    39 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    17 embryo 02-04hr    153 embryo 04-06hr    543 embryo 06-08hr    1258 embryo 08-10hr    1084 embryo 10-12hr    941 embryo 12-14hr    1050 embryo 14-16hr    609 embryo 16-18hr    629 embryo 18-20hr    501 embryo 20-22hr    314 embryo 22-24hr    395 larva L1    233 larva L2    143 larva L3 12hr old    100 larva L3 puffstage 1-2    87 larva L3 puffstage 3-6    237 larva L3 puffstage 7-9    388 white prepupae new    457 white prepupae 12hr    236 white prepupae 24hr    350 pupae 2d postWPP    194 pupae 3d postWPP    78 pupae 4d postWPP    56 adult male 01day    122 adult male 05day    115 adult male 30day    60 adult female 01day    68 adult female 05day    35 adult female 30day    39 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    17 embryo 02-04hr    153 embryo 04-06hr    543 embryo 06-08hr    1258 embryo 08-10hr    1084 embryo 10-12hr    941 embryo 12-14hr    1050 embryo 14-16hr    609 embryo 16-18hr    629 embryo 18-20hr    501 embryo 20-22hr    314 embryo 22-24hr    395 larva L1    233 larva L2    143 larva L3 12hr old    100 larva L3 puffstage 1-2    87 larva L3 puffstage 3-6    237 larva L3 puffstage 7-9    388 white prepupae new    457 white prepupae 12hr    236 white prepupae 24hr    350 pupae 2d postWPP    194 pupae 3d postWPP    78 pupae 4d postWPP    56 adult male 01day    122 adult male 05day    115 adult male 30day    60 adult female 01day    68 adult female 05day    35 adult female 30day    39 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0003944    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0003944 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult thoracico-abdominal ganglion, adult spermathecae. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0003944 expression level Tissue   Expression Level Larval Central Nervous System    92 Larval Midgut    3.5 Larval Hindgut    5 Larval Malpighian Tubules    5 Larval Fat Body    6.8 Larval Salivary Gland    6 Larval Trachea no informative data Larval Carcass    38.6 Adult Head    5.7 Adult Eye    1.75 Adult Brain    5.1 Adult Thoracic-Abdominal Ganglion    196.5 Adult Crop    8 Adult Midgut    7.8 Adult Hindgut    8.6 Adult Malpighian Tubules    4.8 Adult Fat Body    71.9 Adult Salivary Gland no informative data Adult Heart    35.35 Adult VirginFemale Spermatheca    159.5 Adult InseminatedFemale Spermatheca    109.4 Adult Ovary    1.1 Adult Testis    2.6 Adult Male Accessory Gland    8.9 Adult Carcass    35.5 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    92 Larval Midgut    3.5 Larval Hindgut    5 Larval Malpighian Tubules    5 Larval Fat Body    6.8 Larval Salivary Gland    6 Larval Trachea no informative data Larval Carcass    38.6 Adult Head    5.7 Adult Eye    1.75 Adult Brain    5.1 Adult Thoracic-Abdominal Ganglion    196.5 Adult Crop    8 Adult Midgut    7.8 Adult Hindgut    8.6 Adult Malpighian Tubules    4.8 Adult Fat Body    71.9 Adult Salivary Gland no informative data Adult Heart    35.35 Adult VirginFemale Spermatheca    159.5 Adult InseminatedFemale Spermatheca    109.4 Adult Ovary    1.1 Adult Testis    2.6 Adult Male Accessory Gland    8.9 Adult Carcass    35.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    92 Larval Midgut    3.5 Larval Hindgut    5 Larval Malpighian Tubules    5 Larval Fat Body    6.8 Larval Salivary Gland    6 Larval Trachea no informative data Larval Carcass    38.6 Adult Head    5.7 Adult Eye    1.75 Adult Brain    5.1 Adult Thoracic-Abdominal Ganglion    196.5 Adult Crop    8 Adult Midgut    7.8 Adult Hindgut    8.6 Adult Malpighian Tubules    4.8 Adult Fat Body    71.9 Adult Salivary Gland no informative data Adult Heart    35.35 Adult VirginFemale Spermatheca    159.5 Adult InseminatedFemale Spermatheca    109.4 Adult Ovary    1.1 Adult Testis    2.6 Adult Male Accessory Gland    8.9 Adult Carcass    35.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    92 Larval Midgut    3.5 Larval Hindgut    5 Larval Malpighian Tubules    5 Larval Fat Body    6.8 Larval Salivary Gland    6 Larval Trachea no informative data Larval Carcass    38.6 Adult Head    5.7 Adult Eye    1.75 Adult Brain    5.1 Adult Thoracic-Abdominal Ganglion    196.5 Adult Crop    8 Adult Midgut    7.8 Adult Hindgut    8.6 Adult Malpighian Tubules    4.8 Adult Fat Body    71.9 Adult Salivary Gland no informative data Adult Heart    35.35 Adult VirginFemale Spermatheca    159.5 Adult InseminatedFemale Spermatheca    109.4 Adult Ovary    1.1 Adult Testis    2.6 Adult Male Accessory Gland    8.9 Adult Carcass    35.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0003944 expression level Tissue   Expression Level Larval Central Nervous System    92 Larval Midgut    3.5 Larval Hindgut    5 Larval Malpighian Tubules    5 Larval Fat Body    6.8 Larval Salivary Gland    6 Larval Trachea no informative data Larval Carcass    38.6 Adult Head    5.7 Adult Eye    1.75 Adult Brain    5.1 Adult Thoracic-Abdominal Ganglion    196.5 Adult Crop    8 Adult Midgut    7.8 Adult Hindgut    8.6 Adult Malpighian Tubules    4.8 Adult Fat Body    71.9 Adult Salivary Gland no informative data Adult Heart    35.35 Adult VirginFemale Spermatheca    159.5 Adult InseminatedFemale Spermatheca    109.4 Adult Ovary    1.1 Adult Testis    2.6 Adult Male Accessory Gland    8.9 Adult Carcass    35.5 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    92 Larval Midgut    3.5 Larval Hindgut    5 Larval Malpighian Tubules    5 Larval Fat Body    6.8 Larval Salivary Gland    6 Larval Trachea no informative data Larval Carcass    38.6 Adult Head    5.7 Adult Eye    1.75 Adult Brain    5.1 Adult Thoracic-Abdominal Ganglion    196.5 Adult Crop    8 Adult Midgut    7.8 Adult Hindgut    8.6 Adult Malpighian Tubules    4.8 Adult Fat Body    71.9 Adult Salivary Gland no informative data Adult Heart    35.35 Adult VirginFemale Spermatheca    159.5 Adult InseminatedFemale Spermatheca    109.4 Adult Ovary    1.1 Adult Testis    2.6 Adult Male Accessory Gland    8.9 Adult Carcass    35.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    92 Larval Midgut    3.5 Larval Hindgut    5 Larval Malpighian Tubules    5 Larval Fat Body    6.8 Larval Salivary Gland    6 Larval Trachea no informative data Larval Carcass    38.6 Adult Head    5.7 Adult Eye    1.75 Adult Brain    5.1 Adult Thoracic-Abdominal Ganglion    196.5 Adult Crop    8 Adult Midgut    7.8 Adult Hindgut    8.6 Adult Malpighian Tubules    4.8 Adult Fat Body    71.9 Adult Salivary Gland no informative data Adult Heart    35.35 Adult VirginFemale Spermatheca    159.5 Adult InseminatedFemale Spermatheca    109.4 Adult Ovary    1.1 Adult Testis    2.6 Adult Male Accessory Gland    8.9 Adult Carcass    35.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    92 Larval Midgut    3.5 Larval Hindgut    5 Larval Malpighian Tubules    5 Larval Fat Body    6.8 Larval Salivary Gland    6 Larval Trachea no informative data Larval Carcass    38.6 Adult Head    5.7 Adult Eye    1.75 Adult Brain    5.1 Adult Thoracic-Abdominal Ganglion    196.5 Adult Crop    8 Adult Midgut    7.8 Adult Hindgut    8.6 Adult Malpighian Tubules    4.8 Adult Fat Body    71.9 Adult Salivary Gland no informative data Adult Heart    35.35 Adult VirginFemale Spermatheca    159.5 Adult InseminatedFemale Spermatheca    109.4 Adult Ovary    1.1 Adult Testis    2.6 Adult Male Accessory Gland    8.9 Adult Carcass    35.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea no informative data Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    5.7   NA  Eye    1.75   NA  Brain    5.1   92  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    196.5   NA  Crop    8   3.5  Midgut    7.8   5  Hindgut    8.6   5  Malpighian Tubules    4.8   6.8  Fat Body    71.9   6  Salivary Gland    no informative data   NA  Heart    35.35   no informative data  Trachea    NA   NA  VirginFemale Spermatheca    159.5   NA  InseminatedFemale Spermatheca    109.4   NA  Ovary    1.1   NA  Testis    2.6   NA  Male Accessory Gland    8.9   38.6  Carcass    35.5 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_11
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0003944 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10388-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Ubx Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal Ubx195rx1 UbxLDN UbxMX6 lethal, with Scer\GAL469B UbxScer\UAS.cMa lethal, with Scer\GAL4l(3)31-1-31-1 UbxScer\UAS.cMa lethal, with Scer\GAL4prd.RG1 UbxScer\UAS.cMa lethal | embryonic stage, with Scer\GAL4how-24B UbxScer\UAS.cMa lethal | embryonic stage | heat sensitive Ubxhs.PG UbxIa.hs UbxIb.hs UbxIVa.hs UbxΔNN.hs UbxΔSN.hs lethal | embryonic stage | recessive Ubx25 Ubxhs.PM lethal | heat sensitive Ubxhs.PG lethal | larval stage | recessive UbxUbx-Plac61 lethal | male, with Scer\GAL4Bx-MS1096 UbxScer\UAS.cCa lethal | pharate adult stage (with UbxHC180Bα.Scer\FRT) UbxHC180Bβ.Scer\FRT lethal | pharate adult stage (with UbxHC180Bβ.Scer\FRT) UbxHC180Bα.Scer\FRT lethal | pharate adult stage | recessive Ubxbxd-Plac31B UbxHC71-1.HC166D.Del.Rec UbxHC166D.Scer\FRT UbxHC174B.Scer\FRT UbxHC174B UbxHC180Bα UbxHC180Bβ lethal | recessive Ubx130 UbxA UbxC1 UbxCbx-1RM UbxCbx-2 UbxCbx-Hm UbxHC182F.Scer\FRT UbxHC188.Scer\FRT Ubxlac1 UbxMX1 UbxMX2 UbxMX3 UbxMX4 UbxMX5 UbxPlac31 semi-lethal | recessive UbxCPTI000601 viable Ubx61d UbxA Ubxbx-3 Ubxbx-W UbxCbx-1 UbxM4 UbxMX17 viable, with Scer\GAL4pnr-MD237 UbxGD5049 viable (with Ubx101) Ubxpbx-1 viable (with Ubxpbx-1) Ubx101 viable | recessive UbxM2 UbxM3 UbxM4 UbxM5 UbxM6 viable | reduced Ubx61d Sterility Allele fertile UbxA Ubxbx-W Other Phenotypes Allele decreased cell size | cell autonomous | somatic clone Ubx1 neuroanatomy defective Ubxbx-3 Ubxpbx-1 neuroanatomy defective | third instar larval stage, with Scer\GAL4ppk.PG UbxScer\UAS.cUa visible UbxA Ubxabx-1 Ubxbx-3 Ubxbx-34e UbxMX17 UbxMX19 Ubxpbx-1 visible, with Df(3R)Ubx109, Scer\GAL4ptc-559.1 UbxdsRNA.IR.Scer\UAS visible, with Scer\GAL4Bx-MS1096 UbxIVa.Scer\UAS.cRa UbxScer\UAS.cCa visible, with Scer\GAL4dpp.blk1 UbxIa.Scer\UAS.cRa UbxScer\UAS.cCa visible, with Scer\GAL4ey.PH UbxScer\UAS.cCa visible, with Scer\GAL4sca-109-68 UbxIa.Scer\UAS.cRa visible, with Scer\GAL4sd.PU UbxIVa.Scer\UAS.cRa UbxScer\UAS.cCa visible, with Scer\GAL4vg.PM UbxScer\UAS.cCa visible, with Ubxabx-1, Ubxpbx-1/UbxLDN Ubxbx-3 visible, with Ubxbx-3, Ubxpbx-1/UbxLDN Ubxabx-1 visible (with UbxLDN), with Ubxabx-1, Ubxbx-3 Ubxpbx-1 visible (with Ubxpbx-1), with Ubxabx-1, Ubxbx-3 UbxLDN visible | dominant Ubx1:Cbx-1 Ubx1 Ubx6.28 Ubx9.22 Ubx25 Ubx50.1 Ubx61d Ubx130 Ubx175.1 Ubx195 Ubxbxd-100 Ubxbxd-101 Ubxbxd-106 Ubxbxd-110 Ubxbxd-113 Ubxbxd-114 Ubxbxd-125 Ubxbxd-183 Ubxbxd-657 Ubxbxd-DB1 UbxCbx-1 UbxCbx-1RM UbxCbx-2 UbxCbx-2RM UbxCbx-3 UbxCbx-Hm UbxCbx-M1 UbxCbx-M4 UbxCbx-Twt UbxI.7 UbxM1 UbxU UbxUab-1 UbxWup visible | dominant | homeotic Ubx1 UbxCbx-1 UbxCbx-1RM UbxCbx-2 UbxCbx-3 UbxCbx-Hm UbxCbx-M1 Ubxlac1-GAL4 Ubxunspecified visible | heat sensitive UbxIa.hs visible | homeotic Ubx1 Ubxabx-1 Ubxabx-2 Ubxbx-1 Ubxbx-3 Ubxbx-34e UbxCbx-Hm Ubxlac1-GAL4 visible | homeotic, with Df(3R)P2, Ubx61d, Ubxabx-1/Ubxpbx-1 Ubxbx-3 visible | homeotic, with Df(3R)P2, Ubx61d, Ubxbx-3/Ubxpbx-1 Ubxabx-1 visible | homeotic, with Df(3R)P2, Ubx61d, Ubxpbx-1/Ubxbx-3 Ubxabx-1 visible | homeotic, with Df(3R)P2, Ubxabx-1, Ubxbx-3/Ubxpbx-1 Ubx61d visible | homeotic, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubx61d Ubxbx-3 visible | homeotic, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubxbx-3 Ubx61d visible | homeotic, with Df(3R)P2, Ubxbx-3, Ubxabx-1/Ubxpbx-1 Ubx61d visible | homeotic, with Df(3R)P2, Ubxbx-3, Ubxpbx-1/Ubx61d Ubxabx-1 visible | homeotic, with Scer\GAL4arm.PS UbxIa.Scer\UAS.hs.T:Ivir\HA1 UbxIa.Δ2-19.Scer\UAS.hs.T:Ivir\HA1 UbxIa.Δ20-61.Scer\UAS.hs.T:Ivir\HA1 UbxIa.Δ62-82.Scer\UAS.hs.T:Ivir\HA1 UbxIa.Δ83-141.Scer\UAS.hs.T:Ivir\HA1 UbxIa.Δ142-185.Scer\UAS.hs.T:Ivir\HA1 UbxIa.Δ190-233.Scer\UAS.hs.T:Ivir\HA1 UbxIa.Δ234-251.Scer\UAS.hs.T:Ivir\HA1 UbxIa.Δ252-280.Scer\UAS.hs.T:Ivir\HA1 visible | homeotic, with Scer\GAL4arm.PS, UbxIa.Δ20-61.Scer\UAS.hs.T:Ivir\HA1 UbxIa.Δ234-251.Scer\UAS.hs.T:Ivir\HA1 visible | homeotic, with Scer\GAL4arm.PS, UbxIa.Δ234-251.Scer\UAS.hs.T:Ivir\HA1 UbxIa.Δ20-61.Scer\UAS.hs.T:Ivir\HA1 visible | homeotic, with Ubxabx-1, Ubxbx-3/Ubxpbx-1 UbxLDN visible | homeotic, with Ubxabx-1, Ubxpbx-1/Ubxbx-3 UbxLDN visible | homeotic, with Ubxabx-1, Ubxpbx-1/UbxLDN Ubxbx-3 visible | homeotic, with Ubxbx-3, Ubxabx-1/Ubxpbx-1 UbxLDN visible | homeotic, with Ubxbx-3, Ubxpbx-1/UbxLDN Ubxabx-1 visible | homeotic, with Ubxbx-3/Ubxpbx-1 Ubx6.28 visible | homeotic, with UbxLDN, Ubxabx-1/Ubxpbx-1 Ubxbx-3 visible | homeotic, with UbxLDN, Ubxbx-3/Ubxpbx-1 Ubxabx-1 visible | homeotic, with UbxLDN, Ubxpbx-1/Ubxbx-3 Ubxabx-1 visible | homeotic, with Ubxpbx-1/Ubx6.28 Ubxbx-3 visible | homeotic, with Ubxpbx-1/Ubx61d Ubxbx-34e visible | homeotic, with Ubxpbx-1/Ubxbx-3 Ubx6.28 visible | homeotic, with Ubxpbx-1/Ubxbx-34e Ubx61d visible | homeotic (with Df(3R)P2) Ubxabx-1 Ubxbx-3 Ubxbxd-100 Ubxpbx-1 visible | homeotic (with Ubx6.28), with Ubxbx-3 Ubxpbx-1 visible | homeotic (with Ubx61d), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubxpbx-1 visible | homeotic (with Ubx61d), with Ubxbx-34e Ubxpbx-1 visible | homeotic (with Ubxabx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxpbx-1 visible | homeotic (with Ubxabx-1), with UbxLDN, Ubxbx-3 Ubxpbx-1 visible | homeotic (with Ubxbx-3), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxpbx-1 visible | homeotic (with Ubxbx-3), with Ubx6.28 Ubxpbx-1 visible | homeotic (with Ubxbx-3), with UbxLDN, Ubxabx-1 Ubxpbx-1 visible | homeotic (with Ubxbx-34e), with Ubx61d Ubxpbx-1 visible | homeotic (with UbxLDN), with Ubxabx-1, Ubxbx-3 Ubxpbx-1 visible | homeotic (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxbx-3 visible | homeotic (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxabx-1 visible | homeotic (with Ubxpbx-1), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubx61d visible | homeotic (with Ubxpbx-1), with Ubx6.28 Ubxbx-3 visible | homeotic (with Ubxpbx-1), with Ubx61d Ubxbx-34e visible | homeotic (with Ubxpbx-1), with Ubxabx-1, Ubxbx-3 UbxLDN visible | homeotic (with Ubxpbx-1), with Ubxbx-3 Ubx6.28 visible | homeotic (with Ubxpbx-1), with Ubxbx-34e Ubx61d visible | homeotic (with Ubxpbx-1), with UbxLDN, Ubxabx-1 Ubxbx-3 visible | homeotic (with Ubxpbx-1), with UbxLDN, Ubxbx-3 Ubxabx-1 visible | homeotic | recessive Ubxbx-3 UbxCbx-1 Ubxpbx-1 Ubxpbx-2 visible | homeotic | recessive | heat sensitive Ubxbx-1 visible | homeotic | somatic clone, with Scer\GAL4Act5C.PI UbxIa.Scer\UAS.cRa visible | homeotic | somatic clone | heat sensitive Ubxhs.PG visible | recessive Ubxabx-1 Ubxabx-2 Ubxabx-CAC4 Ubxbxd-1 Ubxbxd-51j Ubxbxd-55i Ubxbxd-111 Ubxbxd-127 Ubxbxd-DB3 Ubxbxd-DB6 Ubxbxd-K UbxCbx-2 visible | recessive | somatic clone Ubx1 visible | somatic clone Ubx1 Ubx6.28 wild-type Ubx1 Ubx9.22 Ubxbx-4 Ubxbxd-100 UbxHC16-1 UbxHC71-1.HC166D.Dup.Rec.ry+ UbxHC71-1.HC166D.Dup.Rec.ry- UbxHC71-1.Scer\FRT UbxHC71-1 UbxHC148A.Scer\FRT UbxHC154A UbxHC179.Scer\FRT UbxHC179 UbxHC182F UbxHCJ190 Phenotype manifest in Allele abdominal 1 dorsal transverse muscle 1 UbxMX17 abdominal 1 lateral monoscolopidial chordotonal organ lch1 | heat sensitive UbxIa.hs abdominal 1 lateral transverse muscle UbxMX17 abdominal 1 ventral acute muscle 1 | precursor Ubx9.22 abdominal 1 ventral denticle belt Ubx195 Ubxbxd-1 Ubxbxd-100 Ubxbxd-101 Ubxbxd-106 Ubxbxd-110 Ubxbxd-111 Ubxbxd-113 Ubxbxd-114 Ubxbxd-125 Ubxbxd-127 Ubxbxd-183 Ubxbxd-194 Ubxbxd-51j Ubxbxd-55i Ubxbxd-657 Ubxbxd-DB1 Ubxbxd-DB3 Ubxbxd-DB6 Ubxbxd-K Ubxbxd-Uab1 abdominal 1 ventral denticle belt | ectopic UbxΔQA Ubx6.28 abdominal 1 ventral denticle belt | ectopic, with Scer\GAL4arm.PS UbxScer\UAS.cCa abdominal 1 ventral denticle belt | embryonic stage UbxCbx-2 UbxCbx-Hm UbxUab-1 Ubxbxd-100 Ubxbxd-101 Ubxbxd-106 Ubxbxd-110 Ubxbxd-111 Ubxbxd-113 Ubxbxd-114 Ubxbxd-125 Ubxbxd-127 Ubxbxd-183 Ubxbxd-657 Ubxbxd-DB1 Ubxbxd-DB3 Ubxbxd-DB6 abdominal 2 dorsal transverse muscle 1 UbxMX17 abdominal 2 lateral transverse muscle UbxMX17 abdominal 2 ventral acute muscle 1 | precursor Ubx9.22 abdominal 2 ventral denticle belt | ectopic Ubx195 abdominal 11 anal tuft, with Scer\GAL469B UbxScer\UAS.cCa abdominal anterior fascicle & abdominal segment 1 & adult Ubxbxd-1 Ubxbxd-100 Ubxbxd-125 Ubxpbx-1 abdominal posterior fascicle & abdominal segment 1 & adult Ubxbxd-100 Ubxbxd-125 abdominal segment 1 Ubx1 Ubx10A Ubx25 UbxA.hs UbxB.hs UbxC1 UbxC64 UbxC65 UbxCbx-Hm UbxG2 UbxMX12 UbxMX17 UbxMX19 UbxPlac31 UbxUab-1 UbxUab-5 Ubxbx-3 Ubxbxd-1 Ubxbxd-100 Ubxbxd-101 Ubxbxd-106 Ubxbxd-110 Ubxbxd-111 Ubxbxd-113 Ubxbxd-114 Ubxbxd-125 Ubxbxd-127 Ubxbxd-183 Ubxbxd-194 Ubxbxd-51j Ubxbxd-55i Ubxbxd-657 Ubxbxd-DB1 Ubxbxd-DB3 Ubxbxd-DB6 Ubxbxd-K Ubxbxd-Uab1 abdominal segment 1 & haltere | ectopic Ubx6.28 abdominal segment 1 & haltere | ectopic (with Df(3R)Ubx109) UbxΔQA abdominal segment 1 & Keilin's organ | ectopic Ubx6.28 abdominal segment 1 & metathoracic leg | ectopic Ubx6.28 abdominal segment 1 & metathoracic leg | ectopic (with Df(3R)Ubx109) UbxΔQA abdominal segment 1 & puparium & myoblast, with Scer\GAL4how-24B UbxScer\UAS.cCa abdominal segment 1 & puparium & myoblast, with Scer\GAL4NP5169 UbxScer\UAS.cCa abdominal segment 1 & puparium & myofibril, with Scer\GAL4how-24B UbxScer\UAS.cCa abdominal segment 1 & puparium & myofibril, with Scer\GAL4NP5169 UbxScer\UAS.cCa abdominal segment 1 | anterior compartment UbxMX1 UbxMX2 UbxMX3 UbxMX4 UbxMX5 abdominal segment 1 | ectopic UbxE.hs UbxF.hs UbxIa.hs abdominal segment 1 | ectopic, with Scer\GAL4arm.PS UbxScer\UAS.cCa abdominal segment 2 Ubx9.22-C1 UbxC1 UbxMX12 UbxUab-5 Ubxbxd-1 Ubxbxd-100 Ubxbxd-101 Ubxbxd-106 Ubxbxd-110 Ubxbxd-111 Ubxbxd-113 Ubxbxd-114 Ubxbxd-125 Ubxbxd-127 Ubxbxd-183 Ubxbxd-194 Ubxbxd-51j Ubxbxd-55i Ubxbxd-657 Ubxbxd-DB1 Ubxbxd-DB3 Ubxbxd-DB6 Ubxbxd-K Ubxbxd-Uab1 abdominal segment 2 & puparium & myoblast, with Scer\GAL4how-24B UbxScer\UAS.cCa abdominal segment 2 & puparium & myoblast, with Scer\GAL4NP5169 UbxScer\UAS.cCa abdominal segment 2 & puparium & myofibril, with Scer\GAL4how-24B UbxScer\UAS.cCa abdominal segment 2 & puparium & myofibril, with Scer\GAL4NP5169 UbxScer\UAS.cCa abdominal segment 2 | ectopic UbxA.hs UbxB.hs UbxC.hs UbxD.hs abdominal segment 3 Ubx9.22-C1 UbxC1 UbxMX12 Ubxbxd-1 Ubxbxd-100 Ubxbxd-101 Ubxbxd-106 Ubxbxd-110 Ubxbxd-111 Ubxbxd-113 Ubxbxd-114 Ubxbxd-125 Ubxbxd-127 Ubxbxd-183 Ubxbxd-194 Ubxbxd-51j Ubxbxd-55i Ubxbxd-657 Ubxbxd-DB1 Ubxbxd-DB3 Ubxbxd-DB6 Ubxbxd-K Ubxbxd-Uab1 abdominal segment 3 & puparium & myoblast, with Scer\GAL4how-24B UbxScer\UAS.cCa abdominal segment 3 & puparium & myoblast, with Scer\GAL4NP5169 UbxScer\UAS.cCa abdominal segment 3 & puparium & myofibril, with Scer\GAL4how-24B UbxScer\UAS.cCa abdominal segment 3 & puparium & myofibril, with Scer\GAL4NP5169 UbxScer\UAS.cCa abdominal segment 4 Ubx9.22-C1 UbxC1 UbxMX12 Ubxbxd-1 Ubxbxd-100 Ubxbxd-101 Ubxbxd-106 Ubxbxd-110 Ubxbxd-111 Ubxbxd-113 Ubxbxd-114 Ubxbxd-125 Ubxbxd-127 Ubxbxd-183 Ubxbxd-194 Ubxbxd-51j Ubxbxd-55i Ubxbxd-657 Ubxbxd-DB1 Ubxbxd-DB3 Ubxbxd-DB6 Ubxbxd-K Ubxbxd-Uab1 abdominal segment 4 & puparium & myoblast, with Scer\GAL4how-24B UbxScer\UAS.cCa abdominal segment 4 & puparium & myoblast, with Scer\GAL4NP5169 UbxScer\UAS.cCa abdominal segment 4 & puparium & myofibril, with Scer\GAL4how-24B UbxScer\UAS.cCa abdominal segment 4 & puparium & myofibril, with Scer\GAL4NP5169 UbxScer\UAS.cCa abdominal segment 5 Ubx9.22-C1 UbxC1 UbxMX12 Ubxbxd-1 Ubxbxd-100 Ubxbxd-101 Ubxbxd-106 Ubxbxd-110 Ubxbxd-111 Ubxbxd-113 Ubxbxd-114 Ubxbxd-125 Ubxbxd-127 Ubxbxd-183 Ubxbxd-194 Ubxbxd-51j Ubxbxd-55i Ubxbxd-657 Ubxbxd-DB1 Ubxbxd-DB3 Ubxbxd-DB6 Ubxbxd-K Ubxbxd-Uab1 abdominal segment 5 & puparium & myoblast | ectopic, with Scer\GAL4how-24B UbxScer\UAS.cCa abdominal segment 5 & puparium & myoblast | ectopic, with Scer\GAL4NP5169 UbxScer\UAS.cCa abdominal segment 6 Ubx9.22-C1 UbxC1 UbxMX12 Ubxbxd-1 Ubxbxd-100 Ubxbxd-101 Ubxbxd-106 Ubxbxd-110 Ubxbxd-111 Ubxbxd-113 Ubxbxd-114 Ubxbxd-125 Ubxbxd-127 Ubxbxd-183 Ubxbxd-194 Ubxbxd-51j Ubxbxd-55i Ubxbxd-657 Ubxbxd-DB1 Ubxbxd-DB3 Ubxbxd-DB6 Ubxbxd-K Ubxbxd-Uab1 abdominal segment 7 Ubx9.22-C1 UbxC1 UbxMX12 Ubxbxd-1 Ubxbxd-100 Ubxbxd-101 Ubxbxd-106 Ubxbxd-110 Ubxbxd-111 Ubxbxd-113 Ubxbxd-114 Ubxbxd-125 Ubxbxd-127 Ubxbxd-183 Ubxbxd-194 Ubxbxd-51j Ubxbxd-55i Ubxbxd-657 Ubxbxd-DB1 Ubxbxd-DB3 Ubxbxd-DB6 Ubxbxd-K Ubxbxd-Uab1 abdominal segment 8 Ubx9.22-C1 UbxC1 UbxMX12 abdominal tergite 1 UbxΔQA UbxCbx-Hm UbxUab-1 Ubxbxd-1 Ubxbxd-100 Ubxbxd-101 Ubxbxd-106 Ubxbxd-110 Ubxbxd-111 Ubxbxd-113 Ubxbxd-114 Ubxbxd-125 Ubxbxd-127 Ubxbxd-183 Ubxbxd-194 Ubxbxd-266 Ubxbxd-51j Ubxbxd-55i Ubxbxd-657 Ubxbxd-68 Ubxbxd-DB1 Ubxbxd-DB3 Ubxbxd-DB6 Ubxbxd-K Ubxbxd-Plac13 Ubxbxd-Plac31B Ubxbxd-Uab1 Ubxpbx-1 Ubxpbx-2 abdominal tergite 1 (with Ubx6.28) UbxΔQA abdominal tergite 1 (with UbxΔQA) Ubx6.28 abdominal ventral denticle belt | ectopic, with Scer\GAL4arm.PS UbxScer\UAS.T:Ivir\HA1 abdominal ventral denticle belt | ectopic, with Scer\GAL4how-24B UbxScer\UAS.cMa adult abdominal segment 1 UbxCbx-1 Ubxbxd-1 Ubxbxd-51j Ubxbxd-55i adult abdominal segment 1 | anterior compartment (with Df(3R)P2) Ubxbxd-100 adult head, with Scer\GAL4ey.PH UbxScer\UAS.cCa adult mesothoracic segment UbxCbx-1 UbxCbx-1RM UbxCbx-2 UbxCbx-3 UbxCbx-Hm UbxCbx-M1 Ubxabx-1 Ubxabx-2 adult mesothoracic segment | anterior | ectopic (with Ubx6.28) Ubxbx-34e Ubxbx-8 adult mesothoracic segment | anterior | ectopic (with Ubxbx-8) Ubx6.28 adult mesothoracic segment | anterior | ectopic (with Ubxbx-34e) Ubx6.28 adult mesothoracic segment | anterior compartment | ectopic (with Df(3R)P2) Ubxabx-1 Ubxbx-3 adult mesothoracic segment | ectopic, with Df(3R)P2, Ubx61d, Ubxabx-1/Ubxpbx-1 Ubxbx-3 adult mesothoracic segment | ectopic, with Df(3R)P2, Ubx61d, Ubxbx-3/Ubxpbx-1 Ubxabx-1 adult mesothoracic segment | ectopic, with Df(3R)P2, Ubx61d, Ubxpbx-1/Ubxbx-3 Ubxabx-1 adult mesothoracic segment | ectopic, with Df(3R)P2, Ubxabx-1, Ubxbx-3/Ubxpbx-1 Ubx61d adult mesothoracic segment | ectopic, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubx61d Ubxbx-3 adult mesothoracic segment | ectopic, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubxbx-3 Ubx61d adult mesothoracic segment | ectopic, with Df(3R)P2, Ubxbx-3, Ubxabx-1/Ubxpbx-1 Ubx61d adult mesothoracic segment | ectopic, with Df(3R)P2, Ubxbx-3, Ubxpbx-1/Ubx61d Ubxabx-1 adult mesothoracic segment | ectopic (with Ubx61d), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubxpbx-1 adult mesothoracic segment | ectopic (with Ubxabx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxpbx-1 adult mesothoracic segment | ectopic (with Ubxbx-3), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxpbx-1 adult mesothoracic segment | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxbx-3 adult mesothoracic segment | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxabx-1 adult mesothoracic segment | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubx61d adult mesothoracic segment | ectopic | posterior compartment (with Df(3R)P2) Ubxbxd-100 Ubxpbx-1 adult mesothoracic segment | posterior compartment (with Df(3R)P2) Ubxabx-1 adult metathoracic segment UbxCbx-1 Ubxabx-1 Ubxabx-2 Ubxbx-3 Ubxpbx-1 adult metathoracic segment, with Df(3R)P2, Ubx61d, Ubxabx-1/Ubxpbx-1 Ubxbx-3 adult metathoracic segment, with Df(3R)P2, Ubx61d, Ubxbx-3/Ubxpbx-1 Ubxabx-1 adult metathoracic segment, with Df(3R)P2, Ubx61d, Ubxpbx-1/Ubxbx-3 Ubxabx-1 adult metathoracic segment, with Df(3R)P2, Ubxabx-1, Ubxbx-3/Ubxpbx-1 Ubx61d adult metathoracic segment, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubx61d Ubxbx-3 adult metathoracic segment, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubxbx-3 Ubx61d adult metathoracic segment, with Df(3R)P2, Ubxbx-3, Ubxabx-1/Ubxpbx-1 Ubx61d adult metathoracic segment, with Df(3R)P2, Ubxbx-3, Ubxpbx-1/Ubx61d Ubxabx-1 adult metathoracic segment (with Ubx6.28) Ubxbx-34e Ubxbx-8 adult metathoracic segment (with Ubx61d), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubxpbx-1 adult metathoracic segment (with Ubxabx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxpbx-1 adult metathoracic segment (with Ubxbx-3), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxpbx-1 adult metathoracic segment (with Ubxbx-8) Ubx6.28 adult metathoracic segment (with Ubxbx-34e) Ubx6.28 adult metathoracic segment (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxbx-3 adult metathoracic segment (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxabx-1 adult metathoracic segment (with Ubxpbx-1), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubx61d adult metathoracic segment | anterior compartment (with Df(3R)P2) Ubxabx-1 Ubxbx-3 adult metathoracic segment | anterior compartment | ectopic (with Df(3R)P2) Ubxbxd-100 adult metathoracic segment | dorsal Ubxbx-1 Ubxbxd-1 Ubxbxd-51j adult metathoracic segment | posterior compartment (with Df(3R)P2) Ubxbxd-100 Ubxpbx-1 adult metathoracic segment | somatic clone Ubx1 adult muscle system & abdominal segment 1 Ubxabx-1 Ubxbx-3 Ubxpbx-1 adult prothoracic segment | ectopic | posterior compartment (with Df(3R)P2) Ubxabx-1 alula Ubx1:Cbx-1 UbxCbx-1RM alula (with UbxCbx-1RM) UbxCbx-2 alula (with UbxCbx-2) UbxCbx-1RM antenna, with Scer\GAL4dpp.blk1 UbxScer\UAS.cCa antenna, with Scer\GAL4upd-E132 UbxIa.Scer\UAS antenna | heat sensitive UbxΔNN.hs UbxΔSN.hs UbxIVa.hs UbxIa.hs UbxIb.hs aorta primordium Ubx9.22 aorta primordium | anterior Ubx9.22 aorta primordium | anterior, with Scer\GAL4how-24B, Scer\GAL4twi.PG UbxScer\UAS.cCa aorta primordium | ectopic | posterior, with Scer\GAL4how-24B, Scer\GAL4twi.PG UbxScer\UAS.cCa A-subperineurial glial cell | ectopic | heat sensitive Ubxhs.PG A-subperineurial glial cell of abdominal segment 1 Ubx6.28 B-subperineurial glial cell of abdomen | ectopic | heat sensitive Ubxhs.PG B-subperineurial glial cell of abdominal segment 1 Ubx6.28 capitella sensillum trichodeum | ectopic UbxΔQA capitellum Ubx1 Ubx6.28 Ubxlac1-GAL4 capitellum, with Ubxabx-1, Ubxpbx-1/UbxLDN Ubxbx-3 capitellum, with Ubxbx-3, Ubxpbx-1/UbxLDN Ubxabx-1 capitellum (with UbxLDN), with Ubxabx-1, Ubxbx-3 Ubxpbx-1 capitellum (with Ubxpbx-1), with Ubxabx-1, Ubxbx-3 UbxLDN capitellum | somatic clone Ubx1 cardioblast, with Scer\GAL4twi.PG UbxScer\UAS.cCa cephalopharyngeal skeleton, with Scer\GAL4how-24B UbxScer\UAS.cMa chordotonal organ UbxMX17 chordotonal organ & axon Ubx195 UbxMX17 chordotonal organ & axon | conditional ts UbxIa.hs chordotonal organ & mesothoracic segment UbxIVa.hs chordotonal organ & metathoracic segment UbxIVa.hs chordotonal organ & prothoracic segment UbxIVa.hs coxal tergal remotor muscle | ectopic, with Df(3R)P2, Ubx61d, Ubxabx-1/Ubxpbx-1 Ubxbx-3 coxal tergal remotor muscle | ectopic, with Df(3R)P2, Ubx61d, Ubxbx-3/Ubxpbx-1 Ubxabx-1 coxal tergal remotor muscle | ectopic, with Df(3R)P2, Ubx61d, Ubxpbx-1/Ubxbx-3 Ubxabx-1 coxal tergal remotor muscle | ectopic, with Df(3R)P2, Ubxabx-1, Ubxbx-3/Ubxpbx-1 Ubx61d coxal tergal remotor muscle | ectopic, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubx61d Ubxbx-3 coxal tergal remotor muscle | ectopic, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubxbx-3 Ubx61d coxal tergal remotor muscle | ectopic, with Df(3R)P2, Ubxabx-1/Ubxpbx-1 Ubxbx-3 coxal tergal remotor muscle | ectopic, with Df(3R)P2, Ubxbx-3, Ubxabx-1/Ubxpbx-1 Ubx61d coxal tergal remotor muscle | ectopic, with Df(3R)P2, Ubxbx-3, Ubxpbx-1/Ubx61d Ubxabx-1 coxal tergal remotor muscle | ectopic, with Df(3R)P2, Ubxbx-3/Ubxpbx-1 Ubxabx-1 coxal tergal remotor muscle | ectopic, with Df(3R)P2, Ubxpbx-1/Ubxbx-3 Ubxabx-1 coxal tergal remotor muscle | ectopic (with Df(3R)P2) Ubxabx-1 coxal tergal remotor muscle | ectopic (with Ubx61d), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubxpbx-1 coxal tergal remotor muscle | ectopic (with Ubxabx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxpbx-1 coxal tergal remotor muscle | ectopic (with Ubxabx-1), with Df(3R)P2, Ubxbx-3 Ubxpbx-1 coxal tergal remotor muscle | ectopic (with Ubxbx-3), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxpbx-1 coxal tergal remotor muscle | ectopic (with Ubxbx-3), with Df(3R)P2, Ubxabx-1 Ubxpbx-1 coxal tergal remotor muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxbx-3 coxal tergal remotor muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxabx-1 coxal tergal remotor muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubxabx-1 Ubxbx-3 coxal tergal remotor muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubx61d coxal tergal remotor muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubxbx-3 Ubxabx-1 dendrite & dendritic arborising neuron, with Scer\GAL4ppk.PG UbxScer\UAS.cUa denticle & embryonic head segment, with Scer\GAL4arm.PS UbxIa.Scer\UAS.T:Hsim\VP16 denticle | ectopic, with Scer\GAL4arm.PS UbxIa.Scer\UAS.T:Hsim\VP16 denticle belt Ubx195 Ubx6.28 Ubx9.22 UbxIVa.hs UbxJX2 Ubxhs.PM denticle belt, with Scer\GAL4arm.PS UbxIVa.Scer\UAS UbxIa.Scer\UAS UbxIa.UUU.Scer\UAS denticle belt & abdominal segment 9, with Scer\GAL469B UbxScer\UAS.cCa denticle belt | heat sensitive UbxIa.hs direct flight muscle | ectopic, with Df(3R)P2, Ubx61d, Ubxabx-1/Ubxpbx-1 Ubxbx-3 direct flight muscle | ectopic, with Df(3R)P2, Ubx61d, Ubxbx-3/Ubxpbx-1 Ubxabx-1 direct flight muscle | ectopic, with Df(3R)P2, Ubx61d, Ubxpbx-1/Ubxbx-3 Ubxabx-1 direct flight muscle | ectopic, with Df(3R)P2, Ubxabx-1, Ubxbx-3/Ubxpbx-1 Ubx61d direct flight muscle | ectopic, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubx61d Ubxbx-3 direct flight muscle | ectopic, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubxbx-3 Ubx61d direct flight muscle | ectopic, with Df(3R)P2, Ubxabx-1/Ubxpbx-1 Ubxbx-3 direct flight muscle | ectopic, with Df(3R)P2, Ubxbx-3, Ubxabx-1/Ubxpbx-1 Ubx61d direct flight muscle | ectopic, with Df(3R)P2, Ubxbx-3, Ubxpbx-1/Ubx61d Ubxabx-1 direct flight muscle | ectopic, with Df(3R)P2, Ubxbx-3/Ubxpbx-1 Ubxabx-1 direct flight muscle | ectopic, with Df(3R)P2, Ubxpbx-1/Ubxbx-3 Ubxabx-1 direct flight muscle | ectopic (with Df(3R)P2) Ubxabx-1 Ubxbx-3 Ubxbxd-100 direct flight muscle | ectopic (with Ubx61d), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubxpbx-1 direct flight muscle | ectopic (with Ubxabx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxpbx-1 direct flight muscle | ectopic (with Ubxabx-1), with Df(3R)P2, Ubxbx-3 Ubxpbx-1 direct flight muscle | ectopic (with Ubxbx-3), with Df(3R)P2 Ubxpbx-1 direct flight muscle | ectopic (with Ubxbx-3), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxpbx-1 direct flight muscle | ectopic (with Ubxbx-3), with Df(3R)P2, Ubxabx-1 Ubxpbx-1 direct flight muscle | ectopic (with Ubxpbx-1), with Df(3R)P2 Ubxbx-3 direct flight muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxbx-3 direct flight muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxabx-1 direct flight muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubxabx-1 Ubxbx-3 direct flight muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubx61d direct flight muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubxbx-3 Ubxabx-1 dorsal closure embryo, with Scer\GAL4arm.PS UbxScer\UAS.T:Ivir\HA1 dorsal medial muscle | ectopic, with Df(3R)P2, Ubx61d, Ubxabx-1/Ubxpbx-1 Ubxbx-3 dorsal medial muscle | ectopic, with Df(3R)P2, Ubx61d, Ubxbx-3/Ubxpbx-1 Ubxabx-1 dorsal medial muscle | ectopic, with Df(3R)P2, Ubx61d, Ubxpbx-1/Ubxbx-3 Ubxabx-1 dorsal medial muscle | ectopic, with Df(3R)P2, Ubxabx-1, Ubxbx-3/Ubxpbx-1 Ubx61d dorsal medial muscle | ectopic, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubx61d Ubxbx-3 dorsal medial muscle | ectopic, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubxbx-3 Ubx61d dorsal medial muscle | ectopic, with Df(3R)P2, Ubxabx-1/Ubxpbx-1 Ubxbx-3 dorsal medial muscle | ectopic, with Df(3R)P2, Ubxbx-3, Ubxabx-1/Ubxpbx-1 Ubx61d dorsal medial muscle | ectopic, with Df(3R)P2, Ubxbx-3, Ubxpbx-1/Ubx61d Ubxabx-1 dorsal medial muscle | ectopic, with Df(3R)P2, Ubxbx-3/Ubxpbx-1 Ubxabx-1 dorsal medial muscle | ectopic, with Df(3R)P2, Ubxpbx-1/Ubxbx-3 Ubxabx-1 dorsal medial muscle | ectopic (with Df(3R)P2) Ubxbx-3 Ubxbxd-100 dorsal medial muscle | ectopic (with Ubx61d), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubxpbx-1 dorsal medial muscle | ectopic (with Ubxabx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxpbx-1 dorsal medial muscle | ectopic (with Ubxabx-1), with Df(3R)P2, Ubxbx-3 Ubxpbx-1 dorsal medial muscle | ectopic (with Ubxbx-3), with Df(3R)P2 Ubxpbx-1 dorsal medial muscle | ectopic (with Ubxbx-3), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxpbx-1 dorsal medial muscle | ectopic (with Ubxbx-3), with Df(3R)P2, Ubxabx-1 Ubxpbx-1 dorsal medial muscle | ectopic (with Ubxpbx-1), with Df(3R)P2 Ubxbx-3 dorsal medial muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxbx-3 dorsal medial muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxabx-1 dorsal medial muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubxabx-1 Ubxbx-3 dorsal medial muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubx61d dorsal medial muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubxbx-3 Ubxabx-1 dorsal metathorax | somatic clone Ubx1 ectoderm & metathoracic segment Ubxabx-1 Ubxbx-3 Ubxpbx-1 embryonic/first instar larval cuticle, with Scer\GAL4arm.PS UbxIVa.Scer\UAS UbxIa.Scer\UAS UbxIa.UUU.Scer\UAS embryonic/larval dorsal vessel, with Scer\GAL4how-24B UbxScer\UAS.cCa embryonic/larval epidermis UbxmABP embryonic/larval lymph gland Ubx9.22 embryonic/larval lymph gland, with Scer\GAL4how-24B, Scer\GAL4twi.PG UbxScer\UAS.cCa embryonic/larval ostia, with Scer\GAL4twi.PG UbxScer\UAS.cCa embryonic/larval ostia | ectopic, with Scer\GAL4how-24B UbxScer\UAS.cCa embryonic/larval pericardial cell | ectopic, with Scer\GAL4how-24B, Scer\GAL4twi.PG UbxScer\UAS.cCa embryonic/larval posterior spiracle, with Scer\GAL469B UbxScer\UAS.cCa embryonic/larval posterior spiracle, with Scer\GAL4h-1J3 UbxScer\UAS.cCa embryonic abdominal segment Ubx9.22 embryonic abdominal segment 1 Ubx79f embryonic abdominal segment 1, with Scer\GAL4444 UbxIa.Scer\UAS embryonic abdominal segment 1, with Scer\GAL4arm.PS UbxYAAA.Scer\UAS embryonic abdominal segment 1 & abdominal ventral oblique muscle 6 | ectopic, with Scer\GAL4how-24B UbxIa.Scer\UAS embryonic abdominal segment 1 & abdominal ventral transverse muscle 1 | ectopic, with Scer\GAL4how-24B UbxIa.Scer\UAS embryonic abdominal segment 1 | ectopic, with Scer\GAL4arm.PS UbxScer\UAS.cCa embryonic abdominal segment 2 | ectopic, with Scer\GAL4arm.PS UbxYAAA.Scer\UAS embryonic anterior Malpighian tubule Ubx9.22 embryonic brain, with Scer\GAL4sca-537.4 UbxYAAA.Scer\UAS embryonic central nervous system & thoracic segment, with Scer\GAL4Mz1407 UbxScer\UAS.cCa embryonic dorsal vessel Ubx9.22 embryonic epidermis UbxJX2 embryonic epidermis, with Scer\GAL4arm.PS UbxScer\UAS.cCa embryonic head UbxIa.hs embryonic head, with Scer\GAL4arm.PS UbxScer\UAS.T:Ivir\HA1 UbxScer\UAS.cCa embryonic head | heat sensitive UbxΔNN.hs UbxIVa.hs UbxIa.hs UbxIb.hs embryonic head segment, with Scer\GAL4arm.PS UbxIa.Scer\UAS.T:Hsim\VP16 embryonic labial segment | heat sensitive Ubxhs.PG embryonic mandibular segment | heat sensitive Ubxhs.PG embryonic maxillary segment | heat sensitive Ubxhs.PG embryonic mesothoracic segment UbxIa.hs embryonic mesothoracic segment, with Scer\GAL4444 UbxIa.Scer\UAS embryonic mesothoracic segment, with Scer\GAL4arm.PS UbxScer\UAS.cCa embryonic mesothoracic segment | heat sensitive Ubxhs.PG embryonic metathoracic segment UbxIa.hs embryonic metathoracic segment, with Scer\GAL4444 UbxIa.Scer\UAS embryonic metathoracic segment, with Scer\GAL4arm.PS UbxScer\UAS.cCa UbxYAAA.Scer\UAS embryonic metathoracic segment | heat sensitive Ubxhs.PG embryonic pericardial cell Ubx9.22 embryonic pericardial cell, with Scer\GAL4Mef2.PR UbxScer\UAS.cCa embryonic prothoracic segment UbxIa.hs embryonic prothoracic segment, with Scer\GAL4444 UbxIa.Scer\UAS embryonic prothoracic segment, with Scer\GAL4arm.PS UbxScer\UAS.cCa embryonic prothoracic segment | heat sensitive Ubxhs.PG embryonic thoracic segment & ventral longitudinal muscle, with Scer\GAL4how-24B UbxIa.Scer\UAS embryonic tritocerebrum, with Scer\GAL4sca-537.4 UbxScer\UAS.cCa UbxScer\UAS.cMa embryonic visceral muscle Ubx9.22 embryonic visceral muscle | supernumerary, with Scer\GAL4how-24B UbxScer\UAS.cCa external sensory organ Ubx195 external sensory organ | heat sensitive UbxIa.hs eye UbxA Ubxhs.PG eye, with Scer\GAL4dpp.blk1 UbxScer\UAS.cPa eye, with Scer\GAL4ey.PH UbxScer\UAS.cCa eye | heat sensitive UbxIVa.hs UbxIa.hs UbxIb.hs eye-antennal disc Ubxhs.PM eye disc | posterior | somatic clone, with Scer\GAL4αTub84B.PL UbxScer\UAS.cCa gastric caecum, with Scer\GAL4how-24B UbxIa.Scer\UAS giant fiber neuron Ubxabx-1 Ubxbx-3 Ubxpbx-1 gonadal sheath proper primordium | ectopic, with Scer\GAL4twi.PG UbxScer\UAS.cCa haltere UbxΔQA Ubx1 Ubx130 Ubx175.1 Ubx195 Ubx25 Ubx50.1 Ubx6.28 Ubx61d Ubx9.22 UbxA UbxC43 UbxC46 UbxC48 UbxC82 UbxCbx-Hm UbxCbx-M4 UbxHC71-1.HC166D.Del.Rec UbxI.7 UbxMX17 UbxMX19 UbxU UbxUab-1 Ubxabx-1 Ubxabx-2 Ubxabx-CAC4 Ubxbx-1 Ubxbx-3 Ubxbx-34e Ubxbx-34eprv Ubxbx-4 Ubxbx-8 Ubxbx-83Ka Ubxbx-83Kb Ubxbx-9 Ubxbx-AV Ubxbx-F31 Ubxbx-G Ubxbx-Plac61 Ubxbx-W Ubxbxd-1 Ubxbxd-100 Ubxbxd-101 Ubxbxd-106 Ubxbxd-110 Ubxbxd-111 Ubxbxd-113 Ubxbxd-114 Ubxbxd-121 Ubxbxd-125 Ubxbxd-127 Ubxbxd-183 Ubxbxd-194 Ubxbxd-51j Ubxbxd-55i Ubxbxd-657 Ubxbxd-DB1 Ubxbxd-DB3 Ubxbxd-DB6 Ubxbxd-K Ubxbxd-Uab1 Ubxlac1-GAL4 Ubxpbx-1 Ubxpbx-2 Ubxunspecified haltere, with Df(3R)P2, Ubx61d, Ubxabx-1/Ubxpbx-1 Ubxbx-3 haltere, with Df(3R)P2, Ubx61d, Ubxbx-3/Ubxpbx-1 Ubxabx-1 haltere, with Df(3R)P2, Ubx61d, Ubxpbx-1/Ubxbx-3 Ubxabx-1 haltere, with Df(3R)P2, Ubxabx-1, Ubxbx-3/Ubxpbx-1 Ubx61d haltere, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubx61d Ubxbx-3 haltere, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubxbx-3 Ubx61d haltere, with Df(3R)P2, Ubxbx-3, Ubxabx-1/Ubxpbx-1 Ubx61d haltere, with Df(3R)P2, Ubxbx-3, Ubxpbx-1/Ubx61d Ubxabx-1 haltere, with Ubxabx-1, Ubxbx-3/Ubxpbx-1 UbxLDN haltere, with Ubxabx-1, Ubxpbx-1/Ubxbx-3 UbxLDN haltere, with Ubxabx-1, Ubxpbx-1/UbxLDN Ubxbx-3 haltere, with Ubxbx-3, Ubxabx-1/Ubxpbx-1 UbxLDN haltere, with Ubxbx-3, Ubxpbx-1/UbxLDN Ubxabx-1 haltere, with UbxLDN, Ubxabx-1/Ubxpbx-1 Ubxbx-3 haltere, with UbxLDN, Ubxbx-3/Ubxpbx-1 Ubxabx-1 haltere, with UbxLDN, Ubxpbx-1/Ubxbx-3 Ubxabx-1 haltere, with Ubxpbx-1/Ubx61d Ubxbx-34e haltere, with Ubxpbx-1/Ubxbx-34e Ubx61d haltere (with Df(3R)P2) UbxHC71-1.HC166D.Dup.Rec.ry+ Ubxabx-1 haltere (with Ubx1) UbxHC71-1.HC166D.Dup.Rec.ry+ haltere (with Ubx6.28) UbxΔQA Ubxbx-34e Ubxbx-8 haltere (with Ubx9.22) UbxHC71-1.HC166D.Dup.Rec.ry+ haltere (with Ubx61d), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubxpbx-1 haltere (with Ubx61d), with Ubxbx-34e Ubxpbx-1 haltere (with Ubxabx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxpbx-1 haltere (with Ubxabx-1), with UbxLDN, Ubxbx-3 Ubxpbx-1 haltere (with Ubxbx-3), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxpbx-1 haltere (with Ubxbx-3), with UbxLDN, Ubxabx-1 Ubxpbx-1 haltere (with Ubxbx-8) Ubx6.28 haltere (with Ubxbx-34e) Ubx6.28 haltere (with Ubxbx-34e), with Ubx61d Ubxpbx-1 haltere (with Ubxbxd-100) UbxHC71-1.HC166D.Dup.Rec.ry+ haltere (with UbxHC71-1.HC166D.Dup.Rec.ry+) Ubx1 Ubx9.22 Ubxbxd-100 haltere (with UbxLDN), with Ubxabx-1, Ubxbx-3 Ubxpbx-1 haltere (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxbx-3 haltere (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxabx-1 haltere (with Ubxpbx-1), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubx61d haltere (with Ubxpbx-1), with Ubx61d Ubxbx-34e haltere (with Ubxpbx-1), with Ubxabx-1, Ubxbx-3 UbxLDN haltere (with Ubxpbx-1), with Ubxbx-34e Ubx61d haltere (with Ubxpbx-1), with UbxLDN, Ubxabx-1 Ubxbx-3 haltere (with Ubxpbx-1), with UbxLDN, Ubxbx-3 Ubxabx-1 haltere (with UbxΔQA) Ubx6.28 haltere & macrochaeta UbxM1 haltere & macrochaeta | ectopic UbxM1 haltere | anterior Ubxabx-1 Ubxbx-1 Ubxbx-3 haltere | anterior compartment, with Df(3R)Ubx109, Scer\GAL4ptc-559.1 UbxdsRNA.IR.Scer\UAS haltere | ectopic UbxCbx-1 UbxCbx-1RM UbxCbx-2 UbxCbx-Hm haltere | ectopic, with Scer\GAL4Bx-MS1096 UbxIVa.Scer\UAS.cRa UbxScer\UAS.cCa haltere | ectopic, with Scer\GAL4sd.PU UbxIVa.Scer\UAS.cRa UbxScer\UAS.cCa haltere | ectopic | somatic clone, with Scer\GAL4Act5C.PI UbxIa.Scer\UAS.cRa haltere | ectopic | somatic clone | heat sensitive Ubxhs.PG haltere | heat sensitive UbxIVa.hs UbxIa.hs UbxIb.hs Ubxbx-1 haltere | posterior Ubxbxd-K Ubxpbx-1 Ubxpbx-2 haltere | posterior compartment Ubxbxd-Plac31B haltere | somatic clone Ubx1 Ubx6.28 haltere disc | anterior compartment (with Ubx6.28) Ubxbx-3 haltere disc | anterior compartment (with Ubx130) Ubxbx-3 haltere disc | anterior compartment (with Ubxbx-3) Ubx130 Ubx6.28 haltere disc | posterior compartment (with Ubx6.28) Ubxpbx-1 haltere disc | posterior compartment (with Ubx9.22) Ubxpbx-1 haltere disc | posterior compartment (with Ubx130) Ubxpbx-1 haltere disc | posterior compartment (with Ubxpbx-1) Ubx130 Ubx6.28 Ubx9.22 haltere sensillum | ectopic | somatic clone | heat sensitive Ubxhs.PG haltere sensillum | somatic clone Ubx1 head Ubxhs.PM head | heat sensitive UbxΔSN.hs histoblast nest | anterior | dorsal Ubxbxd-100 histoblast nest | ventral Ubxbxd-266 indirect flight muscle, with Scer\GAL41151 UbxIa.Scer\UAS katepimeron Ubxabx-1 Ubxabx-2 Ubxabx-CAC4 Ubxbx-1 Ubxbx-3 Ubxbx-34e Ubxbx-34eprv Ubxbx-4 Ubxbx-8 Ubxbx-83Ka Ubxbx-83Kb Ubxbx-9 Ubxbx-AV Ubxbx-F31 Ubxbx-G Keilin's organ UbxIVa.hs Ubxhs.PG Keilin's organ, with Scer\GAL4arm.PS UbxΔQA.Scer\UAS.T:Ivir\HA1 UbxIVa.Scer\UAS UbxIa.Scer\UAS UbxIa.Scer\UAS.T:Hsim\VP16 UbxIa.UUU.Scer\UAS UbxScer\UAS.T:Ivir\HA1 UbxScer\UAS.cCa Keilin's organ, with Scer\GAL4h-1J3 UbxScer\UAS.cCa Keilin's organ, with Scer\GAL4Kr.PM UbxScer\UAS.cCa Keilin's organ & abdominal segment 1 Ubx195 Keilin's organ | ectopic (with Df(3R)Ubx109) UbxΔQA Keilin's organ | embryonic stage UbxCbx-Hm UbxUab-1 Ubxbxd-100 Ubxbxd-101 Ubxbxd-106 Ubxbxd-110 Ubxbxd-113 Ubxbxd-114 Ubxbxd-125 Ubxbxd-183 Ubxbxd-657 Ubxbxd-DB1 Keilin's organ | embryonic stage | heat sensitive UbxIVa.hs UbxIa.hs UbxIb.hs Keilin's organ | heat sensitive UbxIa.hs Kolbchen Ubxbxd-1 Ubxbxd-100 Ubxbxd-101 Ubxbxd-106 Ubxbxd-110 Ubxbxd-111 Ubxbxd-113 Ubxbxd-114 Ubxbxd-125 Ubxbxd-127 Ubxbxd-183 Ubxbxd-194 Ubxbxd-266 Ubxbxd-51j Ubxbxd-55i Ubxbxd-657 Ubxbxd-68 Ubxbxd-DB1 Ubxbxd-DB3 Ubxbxd-DB6 Ubxbxd-K Ubxbxd-Uab1 Kolbchen, with Scer\GAL4arm.PS UbxScer\UAS.cCa larval abdominal segment 1 UbxΔQA Ubx6.28 UbxUbx-Plac61 Ubxbxd-266 Ubxbxd-68 UbxmABP larval abdominal segment 2 Ubxbxd-266 Ubxbxd-68 larval abdominal segment 3 Ubxbxd-266 Ubxbxd-68 larval abdominal segment 4 Ubxbxd-266 Ubxbxd-68 larval abdominal segment 5 Ubxbxd-266 Ubxbxd-68 larval abdominal segment 6 Ubxbxd-266 Ubxbxd-68 larval abdominal segment 7 Ubxbxd-266 Ubxbxd-68 larval head | heat sensitive Ubxhs.PG larval mesothoracic segment | heat sensitive Ubxhs.PG larval metathoracic segment UbxmABP larval metathoracic segment | ectopic UbxΔQA Ubx6.28 larval metathoracic segment | heat sensitive Ubxhs.PG larval neuromere | embryonic stage, with Scer\GAL4Mz1407 UbxScer\UAS.cCa larval prothoracic segment | heat sensitive Ubxhs.PG lateral oblique dorsal muscle | ectopic, with Df(3R)P2, Ubx61d, Ubxabx-1/Ubxpbx-1 Ubxbx-3 lateral oblique dorsal muscle | ectopic, with Df(3R)P2, Ubx61d, Ubxbx-3/Ubxpbx-1 Ubxabx-1 lateral oblique dorsal muscle | ectopic, with Df(3R)P2, Ubx61d, Ubxpbx-1/Ubxbx-3 Ubxabx-1 lateral oblique dorsal muscle | ectopic, with Df(3R)P2, Ubxabx-1, Ubxbx-3/Ubxpbx-1 Ubx61d lateral oblique dorsal muscle | ectopic, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubx61d Ubxbx-3 lateral oblique dorsal muscle | ectopic, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubxbx-3 Ubx61d lateral oblique dorsal muscle | ectopic, with Df(3R)P2, Ubxabx-1/Ubxpbx-1 Ubxbx-3 lateral oblique dorsal muscle | ectopic, with Df(3R)P2, Ubxbx-3, Ubxabx-1/Ubxpbx-1 Ubx61d lateral oblique dorsal muscle | ectopic, with Df(3R)P2, Ubxbx-3, Ubxpbx-1/Ubx61d Ubxabx-1 lateral oblique dorsal muscle | ectopic, with Df(3R)P2, Ubxbx-3/Ubxpbx-1 Ubxabx-1 lateral oblique dorsal muscle | ectopic, with Df(3R)P2, Ubxpbx-1/Ubxbx-3 Ubxabx-1 lateral oblique dorsal muscle | ectopic (with Df(3R)P2) Ubxabx-1 Ubxbx-3 lateral oblique dorsal muscle | ectopic (with Ubx61d), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubxpbx-1 lateral oblique dorsal muscle | ectopic (with Ubxabx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxpbx-1 lateral oblique dorsal muscle | ectopic (with Ubxabx-1), with Df(3R)P2, Ubxbx-3 Ubxpbx-1 lateral oblique dorsal muscle | ectopic (with Ubxbx-3), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxpbx-1 lateral oblique dorsal muscle | ectopic (with Ubxbx-3), with Df(3R)P2, Ubxabx-1 Ubxpbx-1 lateral oblique dorsal muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxbx-3 lateral oblique dorsal muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxabx-1 lateral oblique dorsal muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubxabx-1 Ubxbx-3 lateral oblique dorsal muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubx61d lateral oblique dorsal muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubxbx-3 Ubxabx-1 leg Ubxbx-3 Ubxbxd-51j leg | ectopic, with Scer\GAL4dpp.blk1 UbxScer\UAS.cCa lymph gland primordium, with Scer\GAL4Mef2.PR UbxScer\UAS.cCa macrochaeta | ectopic UbxM1 Ubxlac1-GAL4 mesothoracic dorsal triscolopidial chordotonal organ dch3 | heat sensitive UbxIa.hs mesothoracic extracoxal depressor muscle 66 Ubxabx-1 Ubxbx-3 Ubxpbx-1 mesothoracic femur UbxIa.hs mesothoracic intersegmental nerve | adult stage | dorsal Ubxbx-34e mesothoracic laterotergite & macrochaeta | ectopic UbxΔQA mesothoracic laterotergite & macrochaeta | ectopic (with Ubx6.28) UbxΔQA mesothoracic laterotergite & macrochaeta | ectopic (with UbxΔQA) Ubx6.28 mesothoracic laterotergite | ectopic UbxΔQA mesothoracic laterotergite | ectopic (with Ubx6.28) UbxΔQA mesothoracic laterotergite | ectopic (with UbxΔQA) Ubx6.28 mesothoracic leg Ubxbx-34e mesothoracic leg | ectopic | somatic clone Ubx1 mesothoracic leg | posterior compartment Ubx80 mesothoracic leg | posterior compartment | somatic clone Ubx1 mesothoracic pleurum | supernumerary UbxHC71-1.HC166D.Del.Rec mesothoracic segment UbxA.hs UbxB.hs UbxCbx-1 Ubxbx-W mesothoracic segment & glial cell | conditional ts Ubxhs.PG mesothoracic segment | anterior compartment UbxIa.hs mesothoracic segment | heat sensitive Ubxhs.PG mesothoracic segment | posterior compartment UbxMX1 UbxMX2 UbxMX3 UbxMX4 UbxMX5 mesothoracic segment | posterior compartment | somatic clone Ubxunspecified mesothoracic segmental nerve | adult stage Ubxabx-1 Ubxabx-2 Ubxbxd-1 Ubxpbx-1 mesothoracic tergum UbxHC71-1.HC166D.Dup.Rec.ry+ mesothoracic tergum (with Df(3R)P2) UbxHC71-1.HC166D.Dup.Rec.ry+ mesothoracic tergum (with Ubx1) UbxHC71-1.HC166D.Dup.Rec.ry+ mesothoracic tergum (with Ubx9.22) UbxHC71-1.HC166D.Dup.Rec.ry+ mesothoracic tergum (with Ubxbxd-100) UbxHC71-1.HC166D.Dup.Rec.ry+ mesothoracic tergum (with UbxHC71-1.HC166D.Dup.Rec.ry+) Ubx1 Ubx9.22 Ubxbxd-100 mesothoracic tibial apical bristle, with Scer\GAL4dpp.blk1 UbxIa.Scer\UAS.cRa mesothoracic tibial apical bristle | ectopic | somatic clone Ubx1 mesothoracic tibial preapical bristle, with Scer\GAL4dpp.blk1 UbxIa.Scer\UAS.cRa mesothoracic tibial preapical bristle, with Scer\GAL4sca-109-68 UbxIa.Scer\UAS.cRa mesothoracic tracheal pit | embryonic stage | heat sensitive UbxIVa.hs UbxIa.hs UbxIb.hs mesothoracic ventral denticle belt, with Scer\GAL4arm.PS UbxIa.Scer\UAS.T:Hsim\VP16 UbxScer\UAS.cCa metathoracic femur | cell non-autonomous | somatic clone Ubx1 metathoracic intersegmental nerve | adult stage | dorsal Ubxabx-1 Ubxabx-2 metathoracic intersegmental nerve | adult stage | ventral Ubxabx-1 Ubxabx-2 metathoracic laterotergite UbxΔQA Ubx175.1 Ubx50.1 UbxCbx-M4 UbxI.7 Ubxabx-1 Ubxbx-34e metathoracic laterotergite (with Ubx6.28) UbxΔQA metathoracic laterotergite (with UbxΔQA) Ubx6.28 metathoracic leg UbxMX17 Ubxabx-1 Ubxabx-2 Ubxabx-CAC4 Ubxbx-3 Ubxbx-34e Ubxbx-34eprv Ubxbx-W Ubxbxd-1 Ubxpbx-1 Ubxpbx-2 metathoracic leg | anterior Ubxabx-1 Ubxabx-2 Ubxabx-CAC4 Ubxbx-1 Ubxbx-3 Ubxbx-34e Ubxbx-34eprv Ubxbx-4 Ubxbx-8 Ubxbx-83Ka Ubxbx-83Kb Ubxbx-9 Ubxbx-AV Ubxbx-F31 Ubxbx-G metathoracic leg | posterior compartment | somatic clone Ubx1 metathoracic leg | somatic clone Ubx1 metathoracic metatarsus UbxMX17 metathoracic metatarsus | cell non-autonomous | somatic clone Ubx1 metathoracic pleurum UbxHC71-1.HC166D.Del.Rec metathoracic segment Ubx25 UbxA.hs UbxB.hs UbxCbx-Hm UbxMX12 UbxUab-1 Ubxabx-1 Ubxbx-3 Ubxbx-W Ubxbxd-100 Ubxbxd-101 Ubxbxd-106 Ubxbxd-110 Ubxbxd-113 Ubxbxd-114 Ubxbxd-125 Ubxbxd-183 Ubxbxd-657 Ubxbxd-DB1 Ubxpbx-1 metathoracic segment & glial cell | conditional ts Ubxhs.PG metathoracic segment | anterior compartment UbxIa.hs UbxMX1 UbxMX2 UbxMX3 UbxMX4 UbxMX5 Ubxabx-1 Ubxabx-2 Ubxabx-CAC4 Ubxbx-3 Ubxbx-34eprv Ubxbx-F31 metathoracic segment | dorsal Ubxabx-1 Ubxabx-2 Ubxabx-CAC4 Ubxbx-1 Ubxbx-3 Ubxbx-34e Ubxbx-34eprv Ubxbx-4 Ubxbx-8 Ubxbx-83Ka Ubxbx-83Kb Ubxbx-9 Ubxbx-AV Ubxbx-F31 Ubxbx-G metathoracic segment | heat sensitive Ubxhs.PG metathoracic segment | posterior compartment UbxMX1 UbxMX2 UbxMX3 UbxMX4 UbxMX5 metathoracic segment | posterior compartment | somatic clone Ubxpbx-1 metathoracic segmental nerve | adult stage Ubxabx-2 Ubxbxd-100 Ubxbxd-125 metathoracic segmental nerve | adult stage | dorsal Ubxabx-1 metathoracic tarsal bristle | ectopic | somatic clone Ubx1 metathoracic tibial preapical bristle | somatic clone Ubx1 metathoracic tracheal pit | embryonic stage | heat sensitive UbxIVa.hs UbxIa.hs UbxIb.hs metathoracic ventral denticle belt UbxΔQA Ubx195 Ubx6.28 metathoracic ventral denticle belt, with Scer\GAL4arm.PS UbxIa.Scer\UAS.T:Hsim\VP16 UbxScer\UAS.T:Ivir\HA1 UbxScer\UAS.cCa metathoracic ventral denticle belt | embryonic stage | heat sensitive UbxIVa.hs UbxIa.hs UbxIb.hs midgut constriction 1, with Scer\GAL4how-24B UbxIa.Scer\UAS UbxIa.Scer\UAS.cRa multidendritic neuron Ubx195 myoblast Ubxabx-1 Ubxbx-3 Ubxpbx-1 parasegment 1 UbxIa.hs parasegment 1 | embryonic stage | heat sensitive UbxΔNN.hs UbxΔSN.hs UbxIVa.hs UbxIa.hs UbxIb.hs parasegment 2 UbxIa.hs parasegment 2 | embryonic stage | heat sensitive UbxΔNN.hs UbxΔSN.hs UbxIVa.hs UbxIa.hs UbxIb.hs parasegment 3 UbxIa.hs parasegment 3 | embryonic stage | heat sensitive UbxΔNN.hs UbxΔSN.hs UbxIVa.hs UbxIa.hs UbxIb.hs parasegment 4 UbxIa.hs parasegment 4 | embryonic stage | heat sensitive UbxΔNN.hs UbxΔSN.hs UbxIVa.hs UbxIa.hs UbxIb.hs parasegment 5 UbxIa.hs parasegment 5 | embryonic stage | heat sensitive UbxΔNN.hs UbxΔSN.hs UbxIVa.hs UbxIa.hs UbxIb.hs peripheral nervous system & mesothoracic segment | conditional ts UbxIa.hs peripheral nervous system & metathoracic segment | conditional ts UbxIa.hs peripheral nervous system & parasegment 5 Ubx195 UbxMX17 peripheral nervous system & parasegment 6 Ubx195 UbxMX17 peripheral nervous system & prothoracic segment | conditional ts UbxIa.hs peripodial epithelium & dorsal mesothoracic disc, with Scer\GAL4426 UbxScer\UAS.cCa peripodial epithelium & dorsal mesothoracic disc, with Scer\GAL4vg.PM UbxScer\UAS.cCa pharynx, with Scer\GAL4how-24B UbxScer\UAS.cMa photoreceptor cell | somatic clone, with Scer\GAL4αTub84B.PL UbxScer\UAS.cCa posterior vertical bristle UbxA postvertical bristle UbxA presumptive embryonic/larval central nervous system Ubxunspecified presumptive embryonic/larval peripheral nervous system | heat sensitive UbxIa.hs prothoracic femur UbxIa.hs prothoracic leg | posterior compartment | somatic clone Ubx1 prothoracic segment UbxA.hs UbxB.hs prothoracic segment & glial cell | conditional ts Ubxhs.PG prothoracic segment | anterior compartment UbxIa.hs prothoracic segment | heat sensitive Ubxhs.PG prothoracic ventral denticle belt, with Scer\GAL4arm.PS UbxIa.Scer\UAS.T:Hsim\VP16 UbxScer\UAS.cCa prothoracic ventral intersegmental muscle | ectopic, with Scer\GAL4how-24B UbxScer\UAS.cMa scutum, with Scer\GAL4C-765 UbxIa.Scer\UAS spiracle Ubx9.22 sternopleural bristle Ubxbx-34e Ubxbx-W sternopleural bristle | ectopic | somatic clone Ubx1 sternopleural bristle | precursor | heat sensitive UbxIa.hs T1 beard, with Scer\GAL4arm.PS UbxScer\UAS.T:Ivir\HA1 T1 beard | embryonic stage, with Scer\GAL4arm.PS UbxIa.Scer\UAS.T:Hsim\VP16 UbxScer\UAS.cCa tarsal segment 1 & leg sensillum, with Scer\GAL4sca-109-68 UbxIa.Scer\UAS.cRa tergosternal muscle | ectopic, with Df(3R)P2, Ubx61d, Ubxabx-1/Ubxpbx-1 Ubxbx-3 tergosternal muscle | ectopic, with Df(3R)P2, Ubx61d, Ubxbx-3/Ubxpbx-1 Ubxabx-1 tergosternal muscle | ectopic, with Df(3R)P2, Ubx61d, Ubxpbx-1/Ubxbx-3 Ubxabx-1 tergosternal muscle | ectopic, with Df(3R)P2, Ubxabx-1, Ubxbx-3/Ubxpbx-1 Ubx61d tergosternal muscle | ectopic, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubx61d Ubxbx-3 tergosternal muscle | ectopic, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubxbx-3 Ubx61d tergosternal muscle | ectopic, with Df(3R)P2, Ubxabx-1/Ubxpbx-1 Ubxbx-3 tergosternal muscle | ectopic, with Df(3R)P2, Ubxbx-3, Ubxabx-1/Ubxpbx-1 Ubx61d tergosternal muscle | ectopic, with Df(3R)P2, Ubxbx-3, Ubxpbx-1/Ubx61d Ubxabx-1 tergosternal muscle | ectopic, with Df(3R)P2, Ubxbx-3/Ubxpbx-1 Ubxabx-1 tergosternal muscle | ectopic, with Df(3R)P2, Ubxpbx-1/Ubxbx-3 Ubxabx-1 tergosternal muscle | ectopic (with Df(3R)P2) Ubxabx-1 Ubxbx-3 Ubxbxd-100 tergosternal muscle | ectopic (with Ubx61d), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubxpbx-1 tergosternal muscle | ectopic (with Ubxabx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxpbx-1 tergosternal muscle | ectopic (with Ubxabx-1), with Df(3R)P2, Ubxbx-3 Ubxpbx-1 tergosternal muscle | ectopic (with Ubxbx-3), with Df(3R)P2 Ubxpbx-1 tergosternal muscle | ectopic (with Ubxbx-3), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxpbx-1 tergosternal muscle | ectopic (with Ubxbx-3), with Df(3R)P2, Ubxabx-1 Ubxpbx-1 tergosternal muscle | ectopic (with Ubxpbx-1), with Df(3R)P2 Ubxbx-3 tergosternal muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxbx-3 tergosternal muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxabx-1 tergosternal muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubxabx-1 Ubxbx-3 tergosternal muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubx61d tergosternal muscle | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubxbx-3 Ubxabx-1 thoracic neuroblast | larval stage, with Scer\GAL4αTub84B.PL UbxScer\UAS.cCa thoracic segment UbxA.hs UbxB.hs thoracic segment & abdominal ventral acute muscle 1 | precursor | ectopic, with Scer\GAL4how-24B UbxIa.Scer\UAS thorax Ubxhs.PM tracheal metamere 2 | ectopic, with Ubxbx-3/Ubxpbx-1 Ubx6.28 tracheal metamere 2 | ectopic, with Ubxpbx-1/Ubx6.28 Ubxbx-3 tracheal metamere 2 | ectopic, with Ubxpbx-1/Ubxbx-3 Ubx6.28 tracheal metamere 2 | ectopic (with Ubx6.28), with Ubxbx-3 Ubxpbx-1 tracheal metamere 2 | ectopic (with Ubxbx-3), with Ubx6.28 Ubxpbx-1 tracheal metamere 2 | ectopic (with Ubxpbx-1), with Ubx6.28 Ubxbx-3 tracheal metamere 2 | ectopic (with Ubxpbx-1), with Ubxbx-3 Ubx6.28 tracheal metamere 3, with Ubxbx-3/Ubxpbx-1 Ubx6.28 tracheal metamere 3, with Ubxpbx-1/Ubx6.28 Ubxbx-3 tracheal metamere 3, with Ubxpbx-1/Ubxbx-3 Ubx6.28 tracheal metamere 3 (with Ubx6.28), with Ubxbx-3 Ubxpbx-1 tracheal metamere 3 (with Ubxbx-3), with Ubx6.28 Ubxpbx-1 tracheal metamere 3 (with Ubxpbx-1), with Ubx6.28 Ubxbx-3 tracheal metamere 3 (with Ubxpbx-1), with Ubxbx-3 Ubx6.28 tracheal pit UbxCbx-Hm UbxUab-1 Ubxbxd-100 Ubxbxd-101 Ubxbxd-106 Ubxbxd-110 Ubxbxd-113 Ubxbxd-114 Ubxbxd-125 Ubxbxd-183 Ubxbxd-266 Ubxbxd-657 Ubxbxd-68 Ubxbxd-DB1 trichome & mesothoracic femur | posterior UbxIa.hs Ubxst1 trichome & mesothoracic leg UbxΔQA trichome & mesothoracic leg (with Ubx6.28) UbxΔQA trichome & mesothoracic leg (with UbxΔQA) Ubx6.28 trichome & metathoracic leg UbxΔQA trichome & metathoracic leg (with Ubx6.28) UbxΔQA trichome & metathoracic leg (with UbxΔQA) Ubx6.28 trichome of the posterior wing margin UbxIRES.ABXSS ventral metathorax | somatic clone Ubx1 ventral thoracic disc Ubx9.22 wing Ubx1:Cbx-1 UbxA UbxCbx-1 UbxCbx-1RM UbxCbx-2 UbxCbx-Hm UbxCbx-M1 UbxCbx-M4 UbxHC71-1.HC166D.Dup.Rec.ry+ UbxIRES.ABXSS Ubxbx-W Ubxbxd-1 Ubxbxd-100 Ubxbxd-101 Ubxbxd-106 Ubxbxd-110 Ubxbxd-113 Ubxbxd-114 Ubxbxd-125 Ubxbxd-183 Ubxbxd-51j Ubxbxd-55i Ubxbxd-657 Ubxbxd-DB1 Ubxbxd-Plac31A Ubxbxd-Uab1 wing, with Scer\GAL4Bx-MS1096 UbxIVa.Scer\UAS.cRa UbxIa.Scer\UAS UbxScer\UAS.cCa wing, with Scer\GAL4C-765 UbxIa.Scer\UAS wing, with Scer\GAL4dpp.blk1 UbxScer\UAS.cCa wing, with Scer\GAL4sd.PU UbxIVa.Scer\UAS.cRa UbxScer\UAS.cCa wing (with UbxCbx-1RM) UbxCbx-2 wing (with UbxCbx-2) UbxCbx-1RM wing | anterior compartment UbxCbx-3 UbxCbx-Twt wing | ectopic Ubx1 UbxMX17 Ubxbx-34e Ubxunspecified wing | ectopic, with Df(3R)P2, Ubx61d, Ubxabx-1/Ubxpbx-1 Ubxbx-3 wing | ectopic, with Df(3R)P2, Ubx61d, Ubxbx-3/Ubxpbx-1 Ubxabx-1 wing | ectopic, with Df(3R)P2, Ubx61d, Ubxpbx-1/Ubxbx-3 Ubxabx-1 wing | ectopic, with Df(3R)P2, Ubxabx-1, Ubxbx-3/Ubxpbx-1 Ubx61d wing | ectopic, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubx61d Ubxbx-3 wing | ectopic, with Df(3R)P2, Ubxabx-1, Ubxpbx-1/Ubxbx-3 Ubx61d wing | ectopic, with Df(3R)P2, Ubxbx-3, Ubxabx-1/Ubxpbx-1 Ubx61d wing | ectopic, with Df(3R)P2, Ubxbx-3, Ubxpbx-1/Ubx61d Ubxabx-1 wing | ectopic, with Ubxabx-1, Ubxpbx-1/UbxLDN Ubxbx-3 wing | ectopic, with Ubxbx-3, Ubxpbx-1/UbxLDN Ubxabx-1 wing | ectopic (with Df(3R)P2) Ubxabx-1 wing | ectopic (with Ubx6.28) Ubxbx-34e Ubxbx-8 wing | ectopic (with Ubx61d), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubxpbx-1 wing | ectopic (with Ubxabx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxpbx-1 wing | ectopic (with Ubxbx-3), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxpbx-1 wing | ectopic (with Ubxbx-8) Ubx6.28 wing | ectopic (with Ubxbx-34e) Ubx6.28 wing | ectopic (with UbxLDN), with Ubxabx-1, Ubxbx-3 Ubxpbx-1 wing | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxabx-1 Ubxbx-3 wing | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubx61d, Ubxbx-3 Ubxabx-1 wing | ectopic (with Ubxpbx-1), with Df(3R)P2, Ubxabx-1, Ubxbx-3 Ubx61d wing | ectopic (with Ubxpbx-1), with Ubxabx-1, Ubxbx-3 UbxLDN wing | ectopic | somatic clone Ubx1 Ubx6.28 wing | posterior UbxCbx-1 Ubxbx-1 wing | posterior compartment UbxCbx-2RM wing | somatic clone, with Scer\GAL4Act5C.PI UbxIa.Scer\UAS.cRa wing | somatic clone | heat sensitive Ubxhs.PG wing | supernumerary UbxHC71-1.HC166D.Del.Rec wing blade, with Scer\GAL4vg.PM UbxScer\UAS.cCa wing cell | somatic clone | heat sensitive Ubxhs.PG wing disc Ubx9.22 wing hair | ectopic Ubxlac1-GAL4 wing hair | somatic clone | heat sensitive Ubxhs.PG wing margin, with Scer\GAL4sd-SG29.1 UbxScer\UAS.cCa wing margin bristle | ectopic Ubx1 Ubxlac1-GAL4 wing sensillum | somatic clone | heat sensitive Ubxhs.PG wing vein UbxCbx-1 UbxIRES.ABXSS wing vein, with Scer\GAL4sd-SG29.1 UbxScer\UAS.cCa wing vein | somatic clone | heat sensitive Ubxhs.PG
Classical Alleles ( 362 )
For All Classical Alleles Show
Allele of Ubx Class Mutagen Stocks Known lesion Ubxbx-34e spontaneous 64 Yes Ubx1 loss of function allele, amorphic allele - genetic evidence spontaneous 41 Yes Ubxbx-1 spontaneous 29 Yes Ubxbx-3 spontaneous 22 Yes Ubx130 hypomorphic allele - genetic evidence X ray 18 Yes Ubxpbx-1 X ray 16 Yes Ubxbxd-1 wild-type allele spontaneous 15 Yes UbxCbx-1 neomorphic allele - genetic evidence X ray 12 Yes UbxP15 X ray 8 -- Ubx9.22 amorphic allele - genetic evidence X ray 7 Yes Ubxabx-1 X ray 7 Yes UbxP18 X ray 6 -- Ubx101 amorphic allele - genetic evidence X ray 5 Yes Ubx+ 5 -- Ubx61d 5 -- Ubx51 ethyl methanesulfonate 4 -- UbxU X ray 4 -- UbxUab-5 ethyl methanesulfonate 3 Yes Ubx80 ethyl methanesulfonate 2 Yes Ubxbxd-100 X ray 2 Yes Ubxbxd-106 2 Yes Ubxbxd-121 wild-type allele X ray 2 Yes UbxCbx-Hm neomorphic allele - genetic evidence 2 Yes Ubxd00281 P-element activity 2 -- Ubx25 antimorphic allele - genetic evidence ethyl methanesulfonate 1 -- Ubx42T X ray 1 -- Ubx4B 1 -- Ubx5.12 X ray 1 Yes Ubx5.2326 X ray 1 Yes Ubx6.26 X ray 1 Yes Ubx8.8 X ray 1 Yes Ubx849 ethyl methanesulfonate 1 Yes Ubxabx-CAC4 PM hybrid dysgenesis 1 Yes Ubxbx-4 1 Yes Ubxbx-83Ka spontaneous 1 Yes Ubxbx-83Kb spontaneous 1 Yes Ubxbx-8 ethyl methanesulfonate 1 Yes Ubxbxd-110 X ray 1 Yes Ubxbxd-113 X ray 1 Yes Ubxbxd-194 X ray 1 -- Ubxbxd-266 1 Yes Ubxbxd-51j wild-type allele spontaneous 1 Yes Ubxbxd-55i spontaneous 1 Yes Ubxbxd-68 X ray 1 Yes Ubxbxd-Uab1 ethyl methanesulfonate 1 Yes UbxCbx-Twt X ray 1 Yes UbxD1 1 -- Ubxf07161 piggyBac transposase 1 -- UbxG2 X ray 1 Yes UbxM4 ethyl methanesulfonate 1 -- UbxP20 X ray 1 -- Ubxpbx-2 X ray 1 Yes UbxR16 X ray 1 -- UbxT7 1 -- UbxΔQA 1 -- Ubx195rx1 amorphic allele - genetic evidence X ray 0 Yes Ubx6.28 amorphic allele - genetic evidence X ray 0 Yes Ubxlac1 loss of function allele, amorphic allele - genetic evidence Delta2-3 0 Yes UbxMX6 amorphic allele - genetic evidence 0 Yes Ubx+.5' recombination SCEI endonuclease FLPase 0 Yes Ubx102 ethyl methanesulfonate 0 -- Ubx105 0 -- Ubx1069 X ray 0 -- Ubx106 ethyl methanesulfonate 0 -- Ubx10 ethyl methanesulfonate 0 -- Ubx10A ethyl nitrosourea 0 -- Ubx111c P-element activity 0 -- Ubx115 0 -- Ubx12.5 X ray 0 Yes Ubx125 X ray 0 -- Ubx12 ethyl methanesulfonate 0 -- Ubx12C ethyl methanesulfonate 0 -- Ubx1343 X ray 0 -- Ubx13 ethyl nitrosourea 0 -- Ubx145 ethyl methanesulfonate 0 -- Ubx147 ethyl methanesulfonate 0 -- Ubx149 ethyl methanesulfonate 0 -- Ubx154 ethyl methanesulfonate 0 -- Ubx159 ethyl methanesulfonate 0 -- Ubx159A ethyl methanesulfonate 0 -- Ubx16K X ray 0 -- Ubx16N X ray 0 -- Ubx16V X ray 0 -- Ubx175.1 Delta2-3 0 Yes Ubx175 ethyl methanesulfonate 0 -- Ubx180 ethyl methanesulfonate 0 -- Ubx18 X ray 0 -- Ubx195 ethyl methanesulfonate 0 Yes Ubx196 X ray 0 -- Ubx19 ethyl nitrosourea 0 -- Ubx1:Cbx-1 recombination 0 -- Ubx1A X ray 0 -- Ubx1K X ray 0 -- Ubx1U 0 -- Ubx1X ethyl methanesulfonate 0 -- Ubx21J ethyl methanesulfonate 0 -- Ubx21R X ray 0 -- Ubx24 0 -- Ubx24K ethyl methanesulfonate 0 -- Ubx27 ethyl methanesulfonate 0 -- Ubx2E 0 -- Ubx2J ethyl methanesulfonate 0 -- Ubx2P X ray 0 -- Ubx2R ethyl methanesulfonate 0 -- Ubx2V ethyl methanesulfonate 0 -- Ubx2W 0 -- Ubx2XT7-49 gene conversion Delta2-3 0 Yes Ubx30 X ray 0 -- Ubx30A X ray 0 -- Ubx311 0 -- Ubx31 0 -- Ubx34 ethyl nitrosourea 0 -- Ubx4.30 X ray 0 Yes Ubx40 X ray 0 -- Ubx43 X ray 0 -- Ubx4 ethyl methanesulfonate 0 -- Ubx4A ethyl methanesulfonate 0 -- Ubx4XT7-49 gene conversion Delta2-3 0 Yes Ubx5.22 X ray 0 -- Ubx50.1 loss of function allele P-element activity 0 Yes Ubx549 X ray 0 -- Ubx56 ethyl nitrosourea 0 -- Ubx5754 0 -- Ubx58 spontaneous 0 -- Ubx59 0 -- Ubx65 X ray 0 -- Ubx66e ethyl methanesulfonate 0 -- Ubx6C X ray 0 -- Ubx6Q 0 -- Ubx757 X ray 0 -- Ubx765 X ray 0 -- Ubx780 ethyl methanesulfonate 0 -- Ubx79f 0 -- Ubx7L X ray 0 -- Ubx7M X ray 0 -- Ubx8.82 ethyl methanesulfonate 0 -- Ubx882 ethyl methanesulfonate 0 -- Ubx88 ethyl methanesulfonate 0 -- Ubx895 X ray 0 -- Ubx8 0 -- Ubx8A 0 -- Ubx8B ethyl methanesulfonate 0 -- Ubx8M X ray 0 -- Ubx8N X ray 0 -- Ubx9.22-C1 recombination 0 -- Ubx961 0 -- Ubx98 ethyl methanesulfonate 0 -- UbxA X ray 0 -- Ubxabx-2 X ray 0 Yes UbxAD 0 -- UbxAG natural population 0 Yes UbxAR 0 -- UbxB104 ethyl methanesulfonate 0 -- UbxB11 ethyl nitrosourea 0 -- UbxB123 ethyl methanesulfonate 0 -- UbxB127 ethyl methanesulfonate 0 -- UbxB160 ethyl methanesulfonate 0 -- UbxB17 ethyl methanesulfonate 0 -- UbxB18 ethyl methanesulfonate 0 -- UbxB18W ethyl methanesulfonate 0 -- UbxB19 ethyl methanesulfonate 0 -- UbxB1A ethyl methanesulfonate 0 -- UbxB1Q ethyl methanesulfonate 0 -- UbxB203 ethyl methanesulfonate 0 -- UbxB22 ethyl methanesulfonate 0 -- UbxB300 ethyl methanesulfonate 0 -- UbxB36 0 -- UbxB3 ethyl methanesulfonate 0 -- UbxB41 ethyl methanesulfonate 0 -- UbxB49 ethyl methanesulfonate 0 -- UbxB54 ethyl methanesulfonate 0 -- UbxB57 ethyl methanesulfonate 0 -- UbxB58 ethyl methanesulfonate 0 -- UbxB5 ethyl methanesulfonate 0 -- UbxB61 ethyl methanesulfonate 0 -- UbxB6 ethyl methanesulfonate 0 -- UbxB78 ethyl methanesulfonate 0 -- UbxB7 ethyl methanesulfonate 0 -- UbxBelt8 X ray 0 -- Ubxbx-34eprv X ray 0 Yes Ubxbx-3rv spontaneous 0 Yes Ubxbx-51j spontaneous 0 -- Ubxbx-9 spontaneous 0 Yes Ubxbx-AF2 spontaneous 0 -- Ubxbx-AF spontaneous 0 -- Ubxbx-AV spontaneous 0 Yes Ubxbx-F31 spontaneous 0 Yes Ubxbx-G spontaneous 0 Yes Ubxbx-Grv spontaneous 0 Yes Ubxbx-IS spontaneous 0 -- Ubxbx-Plac61 P-element activity 0 Yes Ubxbx-W spontaneous 0 -- Ubxbx-x3 0 -- Ubxbx-X spontaneous 0 -- Ubxbxd-101 0 -- Ubxbxd-111 X ray 0 Yes Ubxbxd-114 0 -- Ubxbxd-123 X ray 0 -- Ubxbxd-125 ethyl nitrosourea 0 -- Ubxbxd-127 X ray 0 Yes Ubxbxd-183 ethyl methanesulfonate 0 -- Ubxbxd-552 0 -- Ubxbxd-657 ethyl methanesulfonate 0 -- Ubxbxd-9 spontaneous 0 Yes Ubxbxd-DB1 X ray 0 -- Ubxbxd-DB3 X ray 0 Yes Ubxbxd-DB4 X ray 0 -- Ubxbxd-DB5 X ray 0 -- Ubxbxd-DB6 X ray 0 -- Ubxbxd-DB7 X ray 0 -- Ubxbxd-DB9 X ray 0 -- Ubxbxd-K spontaneous 0 Yes Ubxbxd-MX1 0 -- Ubxbxd-Plac13 P-element activity 0 Yes Ubxbxd-Plac31A P-element activity 0 Yes Ubxbxd-Plac31B P-element activity 0 Yes Ubxbxd-PR spontaneous 0 Yes Ubxbxd-SR spontaneous 0 Yes Ubxbxd-X X ray 0 -- UbxC101 ethyl nitrosourea 0 -- UbxC104 ethyl nitrosourea 0 -- UbxC12 ethyl nitrosourea 0 -- UbxC1 ethyl methanesulfonate 0 Yes UbxC33 ethyl nitrosourea 0 -- UbxC34 ethyl nitrosourea 0 -- UbxC37 ethyl nitrosourea 0 -- UbxC38 ethyl nitrosourea 0 -- UbxC43 ethyl nitrosourea 0 -- UbxC46 ethyl nitrosourea 0 -- UbxC48 ethyl nitrosourea 0 -- UbxC51 ethyl nitrosourea 0 -- UbxC52 ethyl nitrosourea 0 -- UbxC63 ethyl nitrosourea 0 -- UbxC64 ethyl nitrosourea 0 -- UbxC65 ethyl nitrosourea 0 -- UbxC82 ethyl nitrosourea 0 -- UbxC90 ethyl nitrosourea 0 -- UbxC91 ethyl nitrosourea 0 -- UbxC92 ethyl nitrosourea 0 -- UbxC93 ethyl nitrosourea 0 -- UbxC95 ethyl nitrosourea 0 -- UbxC natural population 0 Yes UbxCbx-1RM spontaneous 0 -- UbxCbx-2 neomorphic allele - genetic evidence 0 Yes UbxCbx-2RM spontaneous 0 -- UbxCbx-3 neomorphic allele - genetic evidence X ray 0 Yes UbxCbx-l1 0 -- UbxCbx-l2 0 -- UbxCbx-M1 neomorphic allele - genetic evidence spontaneous X ray 0 -- UbxCbx-M4 Delta2-3 0 Yes UbxCbx-rv1 0 -- UbxCPTI000601 piggyBac transposase 0 Yes UbxCPTI000694 piggyBac transposase 0 Yes Ubxd00398 P-element activity 0 -- UbxD105.17 ethyl nitrosourea 0 -- UbxD natural population 0 Yes UbxE10 X ray 0 -- UbxE12 X ray 0 -- UbxEdK8 ethyl methanesulfonate 0 -- UbxGal4-M1 gene conversion Delta2-3 0 Yes UbxGal4-M3 gene conversion Delta2-3 0 Yes UbxHC109Aα.Scer\FRT P-element activity 0 -- UbxHC109Aα FLPase 0 -- UbxHC109Aβ.Scer\FRT Delta2-3 0 -- UbxHC109Aβ FLPase 0 -- UbxHC148A.Scer\FRT P-element activity 0 -- UbxHC148A FLPase 0 -- UbxHC154A.Scer\FRT P-element activity 0 -- UbxHC154A FLPase 0 -- UbxHC16-1.Scer\FRT P-element activity 0 -- UbxHC16-1 FLPase 0 -- UbxHC166D.Scer\FRT P-element activity 0 -- UbxHC166D FLPase 0 -- UbxHC174B.Scer\FRT P-element activity 0 -- UbxHC174B FLPase 0 -- UbxHC179.Scer\FRT P-element activity 0 -- UbxHC179 FLPase 0 -- UbxHC180Bα.Scer\FRT P-element activity 0 -- UbxHC180Bα FLPase 0 -- UbxHC180Bβ.Scer\FRT P-element activity 0 -- UbxHC180Bβ FLPase 0 -- UbxHC182F.Scer\FRT P-element activity 0 -- UbxHC182F FLPase 0 -- UbxHC184B-HCJ32#2.Scer\FRT FLPase 0 Yes UbxHC184B.Scer\FRT P-element activity 0 -- UbxHC184B FLPase 0 -- UbxHC188.Scer\FRT P-element activity 0 -- UbxHC188 FLPase 0 -- UbxHC71-1.HC166D.Del.Rec FLPase 0 Yes UbxHC71-1.HC166D.Dup.Rec.ry+ FLPase Delta2-3 0 Yes UbxHC71-1.HC166D.Dup.Rec.ry- FLPase Delta2-3 0 Yes UbxHC71-1.Scer\FRT P-element activity 0 -- UbxHC71-1 FLPase 0 -- UbxHCJ190.Scer\FRT Delta2-3 0 -- UbxHCJ190 FLPase 0 -- UbxHCJE24.Scer\FRT P-element activity 0 -- UbxHCJE24 FLPase 0 -- UbxI.7 loss of function allele Delta2-3 0 Yes UbxJ 0 -- UbxJX2 gamma ray 0 Yes UbxK X ray 0 -- UbxKM26 X ray 0 -- UbxKM30 X ray 0 -- Ubxlac1-GAL4 loss of function allele gene conversion 0 Yes UbxLDN Delta2-3 0 -- UbxM1 ethyl methanesulfonate 0 -- UbxM2 ethyl methanesulfonate 0 -- UbxM3 ethyl methanesulfonate 0 -- UbxM5 ethyl methanesulfonate 0 -- UbxM6 ethyl methanesulfonate 0 -- UbxMN1 ethyl nitrosourea 0 -- UbxMX10 0 Yes UbxMX12 0 -- UbxMX15 0 Yes UbxMX16 0 Yes UbxMX17 hypomorphic allele - genetic evidence X ray 0 Yes UbxMX18 0 Yes UbxMX19 hypomorphic allele - genetic evidence X ray 0 Yes UbxMX1 X ray 0 -- UbxMX2 X ray 0 -- UbxMX3 X ray 0 -- UbxMX4 X ray 0 -- UbxMX5 X ray 0 -- UbxMX9 0 Yes UbxPlac31 P-element activity 0 Yes UbxR10 X ray 0 -- UbxR13 X ray 0 -- UbxR14 X ray 0 -- UbxR17 X ray 0 -- UbxR20 X ray 0 -- UbxR22 X ray 0 -- UbxR29 X ray 0 -- UbxR31 X ray 0 -- UbxR32 X ray 0 -- UbxR34 X ray 0 -- UbxR3 X ray 0 -- UbxR40 X ray 0 -- UbxR49 X ray 0 -- UbxR5 X ray 0 -- UbxR6 X ray 0 -- UbxR79 X ray 0 -- Ubxrfg 0 -- UbxS1 0 -- UbxS205-1 X ray 0 -- UbxS205-2 X ray 0 -- UbxS2 0 -- UbxS3 0 -- UbxScer\UASlacZ gene conversion Delta2-3 0 Yes UbxSP73 gamma ray 0 -- Ubxst1 loss of function allele X ray 0 -- UbxT7-23 gene conversion Delta2-3 0 Yes UbxT7-49 gene conversion Delta2-3 0 Yes UbxUab-1 ethyl methanesulfonate 0 Yes UbxUbx-Plac61 Delta2-3 0 Yes Ubxul10#17 X ray 0 -- Ubxunspecified 0 -- UbxWup X ray 0 -- UbxX-A 0 -- UbxX-type 0 -- UbxX31 0 -- UbxX X ray 0 -- UbxΔQA.3' recombination SCEI endonuclease FLPase 0 Yes
Alleles Carried on Transgenic Constructs ( 119 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Ubx Class Mutagen Stocks Known lesion UbxGD5049 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes UbxScer\UAS.cCa in vitro construct - regulatory fusion 2 Yes UbxHMS01403 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes UbxIa.hs gain of function allele in vitro construct - regulatory fusion 1 Yes UbxJF02202 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Ubx4.Scer\UAS.T:Ivir\HA1 in vitro construct - coding region fusion in vitro construct - regulatory fusion 0 Yes Ubx4.Ubi-p63E.T:Ivir\HA1 in vitro construct - coding region fusion in vitro construct - regulatory fusion 0 Yes Ubx4amut.mI.1.Ubi-p63E.T:Ivir\HA1 in vitro construct - site directed mutagenesis 0 Yes Ubx4amut.Scer\UAS.T:Ivir\HA1 in vitro construct - site directed mutagenesis 0 Yes Ubx4amut.ΔmII.Ubi-p63E.T:Ivir\HA1 in vitro construct - site directed mutagenesis 0 Yes Ubx4F1.Scer\UAS.T:Ivir\HA1 in vitro construct - deletion 0 Yes Ubx4F1.Ubi-p63E.T:Ivir\HA1 in vitro construct - deletion 0 Yes Ubx4mI.1.Ubi-p63E.T:Ivir\HA1 in vitro construct - site directed mutagenesis 0 Yes Ubx4mI.2.Ubi-p63E.T:Ivir\HA1 in vitro construct - site directed mutagenesis 0 Yes Ubx4mI.2.ΔmII.Ubi-p63E.T:Ivir\HA1 in vitro construct - site directed mutagenesis 0 Yes Ubx4mImut.Scer\UAS.T:Ivir\HA1 in vitro construct - site directed mutagenesis 0 Yes Ubx4mImut.Ubi-p63E.T:Ivir\HA1 in vitro construct - site directed mutagenesis 0 Yes Ubx4mImut.ΔmII.Ubi-p63E.T:Ivir\HA1 in vitro construct - deletion 0 Yes Ubx4ΔmII.Ubi-p63E.T:Ivir\HA1 in vitro construct - deletion 0 Yes UbxA.hs in vitro construct - site directed mutagenesis 0 Yes UbxAla.m1.Act5C in vitro construct - amino acid replacement 0 Yes UbxAla.m2.Act5C in vitro construct - amino acid replacement 0 Yes UbxAla.m3.Act5C in vitro construct - amino acid replacement 0 Yes UbxB.hs in vitro construct - site directed mutagenesis 0 Yes Ubxbx.2XT7-49 in vitro construct - regulatory fusion 0 Yes Ubxbx.T7-23 in vitro construct - regulatory fusion 0 Yes Ubxbx.T7-49 in vitro construct - regulatory fusion 0 Yes UbxC.hs in vitro construct - site directed mutagenesis 0 Yes UbxCt.Act5C.T:Scer\GAL4 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes UbxD.hs in vitro construct - site directed mutagenesis 0 Yes Ubxdpp.1400 in vitro construct - regulatory fusion 0 Yes UbxdsRNA.IR.Scer\UAS in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes UbxE.hs in vitro construct - site directed mutagenesis 0 Yes UbxF.hs in vitro construct - site directed mutagenesis 0 Yes UbxFS40.hs in vitro construct 0 Yes Ubxhs.P in vitro construct - regulatory fusion 0 Yes Ubxhs.PG gain of function allele in vitro construct - regulatory fusion 0 Yes Ubxhs.PM in vitro construct - regulatory fusion 0 Yes Ubxhs.v-h in vitro construct - regulatory fusion 0 Yes UbxHX.Scer\UAS in vitro construct - regulatory fusion in vitro construct - amino acid replacement 0 Yes UbxHX.UbdA.Scer\UAS in vitro construct - regulatory fusion in vitro construct - amino acid replacement 0 Yes UbxIa.Act5C in vitro construct 0 Yes UbxIa.HX.Scer\UAS.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion in vitro construct - amino acid replacement 0 Yes UbxIa.Scer\UAS.cRa in vitro construct - regulatory fusion 0 Yes UbxIa.Scer\UAS.hs.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes UbxIa.Scer\UAS.T:Hsim\VP16 in vitro construct - coding region fusion in vitro construct - regulatory fusion 0 Yes UbxIa.Scer\UAS.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes UbxIa.Scer\UAS in vitro construct - regulatory fusion 0 Yes UbxIa.UbdA.Scer\UAS.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion in vitro construct - amino acid replacement 0 Yes UbxIa.UUU.Scer\UAS in vitro construct - regulatory fusion in vitro construct - deletion 0 Yes UbxIa.Δ142-185.Scer\UAS.hs.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion in vitro construct - deletion 0 Yes UbxIa.Δ190-233.Scer\UAS.hs.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion in vitro construct - deletion 0 Yes UbxIa.Δ2-19.Scer\UAS.hs.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion in vitro construct - deletion 0 Yes UbxIa.Δ20-61.Scer\UAS.hs.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion in vitro construct - deletion 0 Yes UbxIa.Δ234-251.Scer\UAS.hs.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion in vitro construct - deletion 0 Yes UbxIa.Δ252-280.Scer\UAS.hs.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion in vitro construct - deletion 0 Yes UbxIa.Δ62-82.Scer\UAS.hs.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion in vitro construct - deletion 0 Yes UbxIa.Δ83-141.Scer\UAS.hs.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion in vitro construct - deletion 0 Yes UbxIaK50.hs in vitro construct - regulatory fusion in vitro construct - genomic fragment 0 Yes UbxIb.Act5C in vitro construct - regulatory fusion 0 Yes UbxIb.hs gain of function allele in vitro construct - regulatory fusion 0 Yes UbxIb.Scer\UAS.cRa in vitro construct - regulatory fusion 0 Yes UbxIIa.Act5C in vitro construct 0 Yes UbxIIa.hs in vitro construct - regulatory fusion 0 Yes UbxIIa.Scer\UAS.cRa in vitro construct - regulatory fusion 0 Yes UbxIIb.Act5C in vitro construct 0 Yes UbxIIb.hs in vitro construct - regulatory fusion 0 Yes UbxIIb.Scer\UAS.cRa in vitro construct - regulatory fusion 0 Yes UbxIRES.ABXSS FLPase 0 Yes UbxIVa.Act5C in vitro construct 0 Yes UbxIVa.hs gain of function allele in vitro construct - regulatory fusion 0 Yes UbxIVa.HX.Scer\UAS.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion in vitro construct - amino acid replacement 0 Yes UbxIVa.Scer\UAS.cRa in vitro construct - regulatory fusion 0 Yes UbxIVa.Scer\UAS.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes UbxIVa.Scer\UAS in vitro construct - regulatory fusion 0 Yes UbxIVa.UbdA.Scer\UAS.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion in vitro construct - amino acid replacement 0 Yes UbxIVaFS.hs in vitro construct - regulatory fusion in vitro construct 0 Yes UbxIVaΔ131-183.Act5C in vitro construct - deletion 0 Yes UbxIVaΔ179-226.Act5C in vitro construct - deletion 0 Yes UbxIVaΔ37-225.Act5C in vitro construct - deletion 0 Yes UbxIVaΔ39-130.Act5C in vitro construct - deletion 0 Yes UbxIVaΔ39-183.Act5C in vitro construct - deletion 0 Yes UbxIVb.Scer\UAS.cRa in vitro construct - regulatory fusion 0 Yes UbxK50.hs in vitro construct - regulatory fusion 0 Yes Ubxlink.Act5C.T:Scer\GAL4 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes UbxLys.dpp.1400 in vitro construct - regulatory fusion in vitro construct - site directed mutagenesis in vitro construct - amino acid replacement 0 Yes UbxLys.m1.Act5C in vitro construct - amino acid replacement 0 Yes UbxLys.m2.Act5C in vitro construct - amino acid replacement 0 Yes UbxmABP in vitro construct - minigene 0 Yes UbxmBPuA in vitro construct - regulatory fusion 0 Yes UbxPro.m1.Act5C in vitro construct - amino acid replacement 0 Yes UbxPro.m2.Act5C in vitro construct - amino acid replacement 0 Yes UbxPro.m3.Act5C in vitro construct - amino acid replacement 0 Yes UbxPro.m4.Act5C in vitro construct - amino acid replacement 0 Yes UbxQA.Act5C.T:Scer\GAL4 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes UbxRI-S.Ubi-p63E in vitro construct - regulatory fusion 0 Yes UbxRI.Ubi-p63E in vitro construct - regulatory fusion 0 Yes UbxRP.Ubi-p63E in vitro construct - regulatory fusion 0 Yes UbxRPmut.Ubi-p63E in vitro construct - site directed mutagenesis 0 Yes UbxSB.Act5C in vitro construct 0 Yes UbxScer\FRT.IRES.ABXSS in vitro construct - regulatory fusion 0 Yes UbxScer\UAS.cCb in vitro construct - regulatory fusion 0 Yes UbxScer\UAS.cMa in vitro construct - regulatory fusion 0 Yes UbxScer\UAS.cPa in vitro construct - regulatory fusion 0 Yes UbxScer\UAS.cUa in vitro construct - regulatory fusion 0 Yes UbxScer\UAS.T:Crei\CD-1-T:Ivir\HA1 in vitro construct - coding region fusion 0 Yes UbxScer\UAS.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes UbxSH.Act5C in vitro construct 0 Yes UbxUbdA.Scer\UAS in vitro construct - regulatory fusion in vitro construct - amino acid replacement 0 Yes UbxUUΔC in vitro construct - deletion 0 Yes UbxX.Act5C in vitro construct 0 Yes UbxYAAA.Scer\UAS in vitro construct - regulatory fusion in vitro construct - amino acid replacement 0 Yes UbxΔNN.hs gain of function allele in vitro construct - deletion 0 Yes UbxΔNUU in vitro construct - deletion 0 Yes UbxΔQA.Scer\SceI.RS in vitro construct 0 Yes UbxΔQA.Scer\UAS.T:Ivir\HA1 in vitro construct - deletion 0 Yes UbxΔRP-N.Ubi-p63E in vitro construct - deletion 0 Yes UbxΔSN.hs gain of function allele in vitro construct - deletion 0 Yes UbxΝ.Act5C in vitro construct - deletion 0 Yes
Aneuploid Aberrations
Duplicated in	Dp(3;1)bxd111   Dp(3;1)O5   Dp(3;1)P68 (Babu et al., 1987, Smolik-Utlaut, 1990) Dp(3;1)P115 (Sanchez-Herrero et al., 1985, Castelli-Gair et al., 1990, Mathog, 1990) Dp(3;1)ry35   Dp(3;2)iab5301 (Hopmann et al., 1995) Dp(3;2)P10 (Lewis, 1978, Lewis, 1980, Bender et al., 1983, Mathog, 1990) Dp(3;3)P5 (Dura et al., 1985, Tiong et al., 1988, Gonzalez-Reyes and Morata, 1990, Smolik-Utlaut, 1990) Dp(3;3)P47 (Craymer, 1984) Dp(3;3)S462 (Castelli-Gair et al., 1990) Dp(3;3)StP563 (Crosby et al., 1993) Dp(3;Y)Abd-BS10 (Tiong et al., 1987, Tiong et al., 1988)
Not disrupted in	Df(3R)C4 (Jurgens, 1988) Df(3R)R1 (Hopmann et al., 1995) Df(3R)R6-41 (Hopmann et al., 1995) Df(3R)RD31 (Hopmann et al., 1995) Df(3R)RK1-13 (Hopmann et al., 1995) Df(3R)RK7-15 (Hopmann et al., 1995) Df(3R)RK8-5 (Hopmann et al., 1995) Df(3R)RK8-7 (Hopmann et al., 1995) Df(3R)RK8-17 (Hopmann et al., 1995) Df(3R)RK8-21 (Hopmann et al., 1995) Df(3R)RS1-98 (Hopmann et al., 1995) Df(3R)RS2-78 (Hopmann et al., 1995) Df(3R)RS3-13 (Hopmann et al., 1995) Df(3R)sbd104 (Tiong et al., 1985) Df(3R)ss-a (Tiong et al., 1985) In(3LR)TM6   T(Y;3)RD26 (Hopmann et al., 1995)
Partially duplicated in	Dp(3;3)bxd100
Disrupted in	Df(3R)abd-A-C1 (Macias et al., 1990, Casanova et al., 1988) Df(3R)Abd-BS10 (Tiong et al., 1987, Tiong et al., 1988) Df(3R)bxd100 (Jurgens et al., 1984, Tiong et al., 1985, Reuter et al., 1990, Castelli-Gair and Garcia-Bellido, 1990, Karch et al., 1990, Frayne and Sato, 1991, Strutt and White, 1994) Df(3R)bxd111 (Kuhn and Woods, 1982) Df(3R)HC184B-HCJ32#2 (Bender and Hudson, 2000) Df(3R)JX2 (Hendrickson and Sakonju, 1995) Df(3R)P2 (Tiong et al., 1985, Simon et al., 1990, Rauskolb and Wieschaus, 1994) Df(3R)P9 (Maurel-Zaffran et al., 1999, Dura et al., 1985, Tiong et al., 1985, Jurgens, 1985, Jurgens, 1988, Boulet and Scott, 1988, Tiong et al., 1988, Gonzalez-Reyes and Morata, 1990, Castelli-Gair et al., 1990, Micol et al., 1990, Frayne and Sato, 1991, Zink et al., 1991, Rowe and Akam, 1988, Greig and Akam, 1995, LaJeunesse and Shearn, 1995, Azpiazu and Morata, 1998) Df(3R)P10 (Kuzin et al., 1997, Tiong et al., 1985) Df(3R)P47 (Craymer, 1984) Df(3R)P115 (Tiong et al., 1985, Tiong et al., 1988) Df(3R)R59 (Foronda et al., 2006) Df(3R)Spf (Carpenter, 1994) Df(3R)Ubx109 (Foronda et al., 2006, Hittinger et al., 2005, Babu and Bhat, 1981, Jimenez and Campos-Ortega, 1981, Tiong et al., 1985, Peifer and Bender, 1986, Jurgens, 1988, Boulet and Scott, 1988, Mann and Hogness, 1990, Reuter et al., 1990, Micol et al., 1990, Little et al., 1990, Frayne and Sato, 1991, Casanova et al., 1988, Rowe and Akam, 1988, Andrew et al., 1994, Greig and Akam, 1995, Hoppler and Bienz, 1995) Df(3R)Ubx9.22abd-A-C1 (Casanova et al., 1988) Df(3R)Ubxabx-1 (Bender et al., 1983) Df(3R)Ubx-C1 (Sanchez-Herrero, 1996.3.7) Df(3R)Ubx-R29 (Bender et al., 1983) Df(3R)Ubx-RS4-8 (Hopmann et al., 1995) In(3)UbxR79 (Bender et al., 1983) In(3LR)UbxU (Craymer, 1984) In(3LR)UbxWup (Carpenter, 1994) In(3R)Cbx3 (Bender et al., 1983) In(3R)Cbxrv1 (Bender et al., 1983) In(3R)CbxTwt (Bender et al., 1983) In(3R)Ubx5.12 (Bender et al., 1983) In(3R)Ubx882 (Bender et al., 1983) In(3R)UbxKM5 (Bender et al., 1983) In(3R)UbxR14 (Bender et al., 1983, Bender et al., 1983) In(3R)UbxR20 (Bender et al., 1983, Bender et al., 1983) In(3R)UbxS205-2 (Mathog, 1990) T(2;3)Ubx4-30 (Bender et al., 1983) T(2;3)Ubx6-26 (Bender et al., 1983) T(2;3)Ubx780 (Bender et al., 1983) T(Y;3)UbxS205-1 (Mathog, 1990) Tp(3;3)Ubxabx-1 (Bender et al., 1983) Tp(3;4)UbxKM22 (Bender et al., 1983)
Partially disrupted in	Df(3R)Ubxpbx-1 (Petruk et al., 2006) Df(3R)Ubxpbx-2 (Petruk et al., 2006)
Transgenic Constructs & Insertions
Transgenic Constructs
reporter construct	Name Expression Data P{-1.7Ubx-βgal} No P{-3.1BDsub} No P{-3.1Bsub} No P{-3.1Dsub} No P{-3.1NS} No P{-3.1RS} No P{-3.1Ubx-βgal} No P{-3.1αα} No P{-3.1αβ} No P{3hz} No P{4CRE} No P{4CRE-BC} No P{4CRE-FL} No P{4hz} No P{5CRE} No P{5hz} No P{5UZ} No P{5UZ-neo} No P{-6Ubx-βgal} No P{7hz} No P{22UZ} No P{35UZ} No P{-46Ubx-βgal} No P{60P1} No P{-201Ubx-βgal} No P{-626(sub)Ubx-βgal} No P{-626Bsub} No P{-626Dsub} No P{-626Ubx-βgal} No P{2206Hf} No P{2206R} No P{2212B0.3} No P{2212B6} No P{2212BK} No P{2212H1+PRE} No P{2212H1+PRE+PBX} No P{2212H2.4} No P{2212H3} No P{2212H3+PRE} No P{2212H6.5} No P{2212H6.5+2218R6} No P{2212H6.5+BX1.5} No P{2212H6.5+BX1.5+PBX1.3} No P{2212H6.5+PBX0.6} No P{2212H6.5+PBX1.3} No P{2212HR3.2.HB} No P{2212HR3.2} No P{2212HR3.2+PBX1.3} No P{2212HSt1.6.HB} No P{2212HSt1.6} No P{2212HSt1.6+2218R6} No P{2212HSt1.6+PBX1.3} No P{2212KpR2.2} No P{2212PN0.67} No P{2212Ps3.5} No P{2212Ps3.5+PBX1.3} No P{2212RB1.5} No P{2212RH} No P{2212S1/2+PRE+2218R6} No P{2212S1} No P{2212S2} No P{2212St1.4} No P{2212StP0.5} No P{2212StR1.6.+2212S} No P{2212StR1.6} No P{2218R6} No P{2218R6+PRE} No P{2218R6+PRE+HB} No P{2218R6+R5} No P{2218R} No P{2218S} No P{(FRT.UbxPRE)dpp.WE.Ubx-lacZ} No P{(FRT.UbxPRE)vg.BE.Ubx-lacZ} No P{(FRT.UbxPRE)vg.QE.Ubx-lacZ} No P{(-FRT)dpp.WE.Ubx-lacZ} No P{(-FRT)vg.BE.Ubx-lacZ} No P{(-FRT)vg.QE.Ubx-lacZ} No P{AMNP41} No P{ASSP41} No P{abx1.7} No P{abx2.7} No P{abx2Δ} No P{abx3.2} No P{abx3.6} No P{abx6.8/iab3-11} No P{abx6.8a} No P{abx6.8b} No P{abx6.8c} No P{abx6.8d} No P{abx6.8e} No P{abx6.8HS} No P{abx9.0} No P{abx20} No P{ABX.3136BR} No P{ACUB} No P{ACXB} No P{B5} No P{B33P41} No P{BBI} No P{BC2} No P{BC} No P{Bhz} No P{BI} No P{bluetail} No P{BM1} No P{BM2} No P{BP41} No P{BRE-Ubx-lacZ} No P{BS1S2} No P{bx-17} No P{bxd-3} No P{bxd-5.6} No P{bxd-6} No P{bxd-8/iab2-5.7} No P{bxd-9.4} No P{bxd-10.5} No P{bxd-11.5} No P{bxd14.5} No P{BXD-33} No P{bxd/iab2-7} No P{bxd/iab2-13} No P{bxd/iab2-18} No P{BXD.3105} No P{bxIa-b} No P{bxIa-Pst} No P{bxIa-Ubx-lacZ} No P{bxIb-Ubx-lacZ} No P{bxIc-Ubx-lacZ} No P{bxIII-Ubx-lacZ} No P{bxII-Ubx-lacZ} No P{bxIL} No P{bxI-Ubx-lacZ} No P{ComboA} No P{ComboB} No P{FB} No P{hb-ep} No P{hb-eve} No P{hb-mes} No P{hb-mut} No P{hzA} No P{hzB} No P{hzC} No P{iab2-1.7} No P{iab2-5.7} No P{iab2-17} No P{iab7PRE-BXD} No P{IB} No P{L-4} No P{lacZ.Ubx} No P{lacZUbx.E1HZ} No P{lacZUbx.pbx2xPS} No P{lacZUbx.pbx2xPSc} No P{lacZUbx.pbx4xPSc} No P{lacZUbx.pbxPP} No P{lacZUbx.pbxPPa} No P{lacZUbx.pbxPPb} No P{lacZUbx.pbxPS} No P{lacZUbx.pbxPSc} No P{lacZUbx.pbxPSd} No P{lacZUbx.RP} No P{L-CRE} No P{MB} No P{MBO142} No P{PBX-41} No P{PBX.3101} No P{PBX+2212H1} No P{PBX+2218R6} No P{PBX+2218R6-R5} No P{pbxAP} No P{pbxAS} No P{pbxPB} No P{pbxSB} No P{PBX-UP} No P{R5} No P{R6.Bam0.3} No P{R6.Bam0.5} No P{R6.Cla} No P{R6.ClaHinc.x2} No P{R6.ClaHinc.x3} No P{R6.ClaHinc} No P{R6.Hinc} No P{RPhz} No P{ssDpry} No P{Ubx-7.6} No P{Ubx-10.5} No P{Ubx.B3} No P{Ubx.B3B4} No P{Ubx.B4} No P{Ubx.B4R8} No P{Ubx.B6} No P{Ubx.BE} No P{Ubx.BG} No P{Ubx.BL} No P{Ubx(15-1)lacZ} No P{Ubx(ΔBhz)lacZ} No P{Ubx-lacZ.8XS.iab-8} No P{Ubx-lacZ.8XS-IN.iab-8} No P{Ubx-lacZ.8XSΔHS1-2.iab-7} No P{Ubx-lacZ.8XSΔHS1-2.iab-8} No P{Ubx-lacZ.8XSΔHS1.iab-8} No P{Ubx-lacZ.8XSλ.iab-7} No P{Ubx-lacZ.8XSλ.iab-8} No P{Ubx-lacZ.22UZ.GAGA/NTF-1.3'} No P{Ubx-lacZ.22UZ.GAGA/NTF-1.5'} No P{Ubx-lacZ.22UZ.GAGA/NTF-1.alt} No P{Ubx-lacZ.22UZ.GAGA} No P{Ubx-lacZ.22UZ.NTF-1} No P{Ubx-lacZ.22UZ.ZESTE/NTF-1} No P{Ubx-lacZ.22UZ.ZESTE} No P{Ubx-lacZ.22UZ.Δ} No P{Ubx-lacZ.AB} No P{Ubx-lacZ.ABP} No P{Ubx-lacZ.ABX} No P{Ubx-lacZ.AP} No P{Ubx-lacZ.BA} No P{Ubx-lacZ.BP} No P{Ubx-lacZ.BPA} No P{Ubx-lacZ.bxd/pbx.N.4} No P{Ubx-lacZ.bxd/pbx.N} No P{Ubx-lacZ.bxd/pbx.ΔA} No P{Ubx-lacZ.bxd/pbx.ΔB.4} No P{Ubx-lacZ.bxd/pbx.ΔB} No P{Ubx-lacZ.bxd/pbx.ΔBC1.4} No P{Ubx-lacZ.bxd/pbx.ΔBC1-A.4} No P{Ubx-lacZ.bxd/pbx.ΔBC1-B.4} No P{Ubx-lacZ.bxd/pbx.ΔBC1-C.4} No P{Ubx-lacZ.bxd/pbx.ΔBC1-D.4} No P{Ubx-lacZ.bxd/pbx.ΔBC1-Dmut.4} No P{Ubx-lacZ.bxd/pbx.ΔBC2.4} No P{Ubx-lacZ.bxd/pbx.ΔBC3.4} No P{Ubx-lacZ.bxd/pbx.ΔBC3-PHO1-2.4} No P{Ubx-lacZ.bxd/pbx.ΔBC3-PHO1.4} No P{Ubx-lacZ.bxd/pbx.ΔBC3-PHO2.4} No P{Ubx-lacZ.bxd/pbx.ΔBC} No P{Ubx-lacZ.bxd/pbx.ΔC1} No P{Ubx-lacZ.bxd/pbx.ΔC3} No P{Ubx-lacZ.bxd/pbx.ΔC} No P{Ubx-lacZ.bxd/pbx.ΔD} No P{Ubx-lacZ.BXD.en.1.8} No P{Ubx-lacZ.BXD.en.2.6} No P{Ubx-lacZ.BXD} No P{Ubx-lacZ.BΒA} No P{Ubx-lacZ.BΒP} No P{Ubx-lacZ.L} No P{Ubx-lacZ.PA} No P{Ubx-lacZ.PB} No P{Ubx-lacZ.PBX.IDE} No P{Ubx-lacZ.PBX.PRE1.6.IDE} No P{Ubx-lacZ.PBX.PREA.IDE} No P{Ubx-lacZ.PBX.PREB.IDE} No P{Ubx-lacZ.PBX.PREC.IDE} No P{Ubx-lacZ.PBX.PRED.IDE} No P{Ubx-lacZ.PBX.PREDGAGAmut.IDE} No P{Ubx-lacZ.PBX.PREDmutpho.IDE} No P{Ubx-lacZ.PBX} No P{Ubx-lacZ.Q} No P{Ubx-lacZ.w+} No P{UbxΔD} No P{UβGAGA} No P{UβNTF-1} No P{Uβzeste} No P{UβΔ-200/-31} No P{Δ19UZ} No P{ΔAhz} No P{ΔChz} No P{ΔDI} No P{ΔDII} No P{ΔDIIW} No P{ΔEhz} No P{ΔFhz} No P{Δftz1-3} No P{Δftz1-3mftz4} No P{Δftz1-3Δhb3} No P{Δftz1-4} No P{Δftz3-4} No P{Δftz4} No P{Δftz4Δhb1-2} No P{ΔhbABC-Ubx-lacZ} No P{ΔRhz} No P{ΔW} No
UAS construct	Name Expression Data P{GD5049} NA P{TRiP.HMS01403} NA P{TRiP.JF02202} NA P{UAS-Ubx.4.T:HA1} NA P{UAS-Ubx.4amut.T:HA1} NA P{UAS-Ubx.4F1.T:HA1} NA P{UAS-Ubx.4mImut.T:HA1} NA P{UAS-Ubx.HA} NA P{UAS-Ubx.HX.UbdA} NA P{UAS-Ubx.HX} NA P{UAS-Ubx.Ia.C} NA P{UAS-Ubx.Ia.Cap} NA P{UAS-Ubx.Ia.HX} NA P{UAS-Ubx.Ia.K} NA P{UAS-Ubx.Ia.M} NA P{UAS-Ubx.Ia.R} NA P{UAS-Ubx.Ia.UbdA} NA P{UAS-Ubx.Ia.UUU} NA P{UAS-Ubx.Ia} NA P{UAS-Ubx.Ib.R} NA P{UAS-Ubx.IIa.R} NA P{UAS-Ubx.IIb.R} NA P{UAS-Ubx.IR} NA P{UAS-Ubx.IVa.HX} NA P{UAS-Ubx.IVa.R} NA P{UAS-Ubx.IVa.UbdA} NA P{UAS-Ubx.IVa.W} NA P{UAS-Ubx.IVa} NA P{UAS-Ubx.IVb.R} NA P{UAS-Ubx.M} NA P{UAS-Ubx.P} NA P{UAS-Ubx.T:CD-1} NA P{UAS-Ubx.U} NA P{UAS-Ubx.UbdA} NA P{UAS-Ubx.YAAA} NA P{UAS-Ubx.ΔQA} NA P{UAS-UbxIa.Δ2-19-HA} NA P{UAS-UbxIa.Δ20-61-HA} NA P{UAS-UbxIa.Δ62-82-HA} NA P{UAS-UbxIa.Δ83-141-HA} NA P{UAS-UbxIa.Δ190-233-HA} NA P{UAS-UbxIa.Δ252-280-HA} NA P{UAS-UbxIa-HA} NA P{UAS-Ubx-VP16} NA
heat-shock construct	Name Expression Data P{HS:Ubx-FS40} NA P{HS:Ubx-Ia} NA P{HS:Ubx-Ib} NA P{HS:Ubx-IVa} NA P{HS:Ubx-IVaFS} NA P{HS:Ubx-ΔNN} NA P{HS:Ubx-ΔSN} NA P{Hsp70-abd-A::Ubx.A} NA P{Hsp70-abd-A::Ubx.B} NA P{Hsp70-abd-A::Ubx.C} NA P{Hsp70-abd-A::Ubx.D} NA P{Hsp70-abd-A::Ubx.E} NA P{Hsp70-abd-A::Ubx.F} NA P{HSU} NA P{HS-Ubx.K50} NA P{HS-Ubx.M} NA P{hs-Ubx} NA P{UAS-UbxIa.Δ2-19-HA} NA P{UAS-UbxIa.Δ20-61-HA} NA P{UAS-UbxIa.Δ62-82-HA} NA P{UAS-UbxIa.Δ83-141-HA} NA P{UAS-UbxIa.Δ190-233-HA} NA P{UAS-UbxIa.Δ252-280-HA} NA P{UAS-UbxIa-HA} NA P{UbxIaK50} NA
characterization construct	Name Expression Data P{actUBXIb} NA P{bx10-T7-23} NA P{Dfd::Ubx.hsS1} NA P{Dfd::Ubx.hsS2} NA P{Dfd::Ubx.hsS3} NA P{Dfd::Ubx.hsS4} NA P{Dfd::Ubx.hsS5} NA P{Dfd::Ubx.hsS6} NA P{Dfd/Ubx} NA P{dpp1400Ubx+} NA P{dpp1400UbxLys} NA P{FRT(whs.UbxΔQA.Scer\SceI.RS)} NA P{HS:Ubx-Antp} NA P{hsDfd-Ubx} NA P{Hsp70-abd-A::Ubx.G} NA P{Hsp70-abd-A::Ubx.H} NA P{mBPuA} NA P{pbx2.3BglII-2XT7-49} NA P{pbx2.3BglII-T7-49} NA P{U12} NA P{UA(ala)5U} NA P{UA1,3,23,25,57stop} NA P{UA1,3,23,25stop} NA P{UA1,3,23,57stop} NA P{UA1,3,23stop} NA P{UA1,3,25,35,57stop} NA P{UA1,3stop} NA P{UA23,25,57stop} NA P{UA25,35,57stop} NA P{UAA} NA P{UAS.Antp.HX:UC} NA P{UAS.LEF-1} NA P{UAS-Antp::Ubx.AAAU} NA P{UAS-Antp::Ubx.AAUA} NA P{UAS-Antp::Ubx.AAUU} NA P{UAS-Antp::Ubx.AUAA} NA P{UAS-Antp::Ubx.AUAU} NA P{UAS-Antp::Ubx.AUUU} NA P{UAS-Antp.HX:UC.UbdA} NA P{UAS-Cs-AbdA.DmLR.HX} NA P{UAS-Cs-AbdA.DmLR} NA P{UAS-O/QA} NA P{UAstop} NA P{UAS-Ubx1a::Lox2HD.G} NA P{UAS-Ubx1a::Lox4HD.G} NA P{UAS-Ubx1a::OnyHD.G} NA P{UAS-Ubx::Afra\Ubx.250.ΔQA} NA P{UAS-Ubx::Afra\Ubx.250} NA P{UAS-Ubx::Afra\Ubx.281} NA P{UAS-Ubx::Afra\Ubx.356} NA P{UAS-Ubx::Zzzz\Ubx2.DmLR.HX} NA P{UAS-Ubx::Zzzz\Ubx2.DmLR.UbdA} NA P{UAS-Ubx::Zzzz\Ubx2.DmLR} NA P{UAU} NA P{UAU18} NA P{Ubx+lacZ.ABX.H} NA P{Ubx+lacZ.FRT.H} NA P{Ubx-FLP} NA P{Ubx-lacZ.bxd.NLS} NA P{Ubx-w.PRE.D} NA P{UUA} NA P{UUstop} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{XP}Ubxd00281 NA P{XP}Ubxd00398 NA miscellaneous insertions 412{}Ubxbx-1 NA 412{}Ubxbx-IS NA ?{}Ubxbxd-SR NA Doc{}bx-3rv NA Doc{}Ubx1 NA Doc{}Ubxbx-3rv NA gypsy{}Doc{}89E(bx3) NA gypsy{}Ubxbx-3 NA gypsy{}Ubxbx-9 NA gypsy{}Ubxbx-34e NA gypsy{}Ubxbx-83Ka NA gypsy{}Ubxbx-83Kb NA gypsy{}Ubxbx-AF2 NA gypsy{}Ubxbx-AF NA gypsy{}Ubxbx-AV NA gypsy{}Ubxbxd-1 NA gypsy{}Ubxbxd-9 NA gypsy{}Ubxbxd-51j NA gypsy{}Ubxbxd-55i NA gypsy{}Ubxbxd-121 NA gypsy{}Ubxbxd-K NA gypsy{}Ubxbxd-PR NA gypsy{}Ubxbx-G NA gypsy{}Ubxbx-X NA H{}Ubxabx-CAC4 NA Harvey{}Ubxbx-8 NA I{}Ubxbx-F31 NA P{?'A92}UbxI.7 NA P{bx10-T7-23}UbxT7-23 NA P{bx-17}UbxPlac31 NA P{bxd/iab2-7}Ubxbxd-Plac13 NA P{bxd/iab2-13}Ubxbxd-Plac31A NA P{bxd/iab2-18}Ubxbxd-Plac31B NA P{pbx2.3BglII-2XT7-49}Ubx2XT7-49 NA P{pbx2.3BglII-2XT7-49}Ubx4XT7-49 NA P{pbx2.3BglII-T7-49}UbxT7-49 NA P{UAS-lacZ.B}UbxScer\UASlacZ NA PBac{602.P.SVS-1}UbxCPTI000601 NA PBac{602.P.SVS-1}UbxCPTI000694 NA PBac{WH}Ubxf07161 NA insertion of enhancer trap P{(-FRT)lacZ.HP}UbxHC16-1 No P{(-FRT)lacZ.HP}UbxHC71-1 No P{(-FRT)lacZ.HP}UbxHC109Aα No P{(-FRT)lacZ.HP}UbxHC109Aβ No P{(-FRT)lacZ.HP}UbxHC148A No P{(-FRT)lacZ.HP}UbxHC154A No P{(-FRT)lacZ.HP}UbxHC166D No P{(-FRT)lacZ.HP}UbxHC174B No P{(-FRT)lacZ.HP}UbxHC179 No P{(-FRT)lacZ.HP}UbxHC180Bα No P{(-FRT)lacZ.HP}UbxHC180Bβ No P{(-FRT)lacZ.HP}UbxHC182F No P{(-FRT)lacZ.HP}UbxHC184B No P{(-FRT)lacZ.HP}UbxHC188 No P{(-FRT)lacZ.HP}UbxHCJ190 No P{(-FRT)lacZ.HP}UbxHCJE24 No P{A92}UbxCbx-M4 No P{A92}Ubxlac1 No P{HomingPigeon.FRT}abd-AHC184B-HCJ32#2.Scer\FRT No P{HomingPigeon.FRT}UbxHC16-1.Scer\FRT No P{HomingPigeon.FRT}UbxHC71-1.HC166D.Dup.Rec.ry+ No P{HomingPigeon.FRT}UbxHC71-1.Scer\FRT No P{HomingPigeon.FRT}UbxHC109Aα.Scer\FRT No P{HomingPigeon.FRT}UbxHC109Aβ.Scer\FRT No P{HomingPigeon.FRT}UbxHC148A.Scer\FRT No P{HomingPigeon.FRT}UbxHC154A.Scer\FRT No P{HomingPigeon.FRT}UbxHC166D.Scer\FRT No P{HomingPigeon.FRT}UbxHC174B.Scer\FRT No P{HomingPigeon.FRT}UbxHC179.Scer\FRT No P{HomingPigeon.FRT}UbxHC180Bα.Scer\FRT No P{HomingPigeon.FRT}UbxHC180Bβ.Scer\FRT No P{HomingPigeon.FRT}UbxHC182F.Scer\FRT No P{HomingPigeon.FRT}UbxHC184B.Scer\FRT No P{HomingPigeon.FRT}UbxHC188.Scer\FRT No P{HomingPigeon.FRT}UbxHCJ190.Scer\FRT No P{HomingPigeon.FRT}UbxHCJE24.Scer\FRT No P{MTW}Ubx111c No P{PZ}Ubx50.1 No P{PZ}Ubxbx-Plac61 No P{PZ}UbxUbx-Plac61 No insertion of enhancer trap binary system P{GawB}UbxGal4-M1 No P{GawB}UbxGal4-M3 No P{GawB}Ubxlac1-GAL4 No P{GawB}UbxLDN No
Gene Ontology: Function, Process & Cellular Component ( 25 unique terms )
Terms Based on Experimental Evidence ( 19 terms )
Molecular Function
CV term Evidence References
DNA binding inferred from direct assay (assigned by UniProtKB) (Ekker et al., 1991, Passner et al., 1999) protein binding inferred from physical interaction with DIP1 (Bondos et al., 2004) protein domain specific binding inferred from physical interaction with UniProtKB:P40427 (assigned by UniProtKB) (Passner et al., 1999) RNA polymerase II distal enhancer sequence-specific DNA binding inferred from direct assay (Vachon et al., 1992) sequence-specific DNA binding inferred from direct assay (Pallavi et al., 2006, Ahn et al., 2011, Liu et al., 2008)
Biological Process
CV term Evidence References
cell fate determination inferred from genetic interaction with Asx (Bischoff et al., 2009) inferred from mutant phenotype (Bischoff et al., 2009) haltere development inferred from mutant phenotype (Shashidhara et al., 1999, Pallavi et al., 2006, Mohit et al., 2006) heart development inferred from expression pattern (Lo et al., 2002) inferred from mutant phenotype (Ponzielli et al., 2002, Lovato et al., 2002) imaginal disc-derived leg morphogenesis inferred from mutant phenotype (Stern, 2003) mesodermal cell fate specification inferred from mutant phenotype (Ponzielli et al., 2002) negative regulation of gene silencing inferred from direct assay (Smith et al., 2011) negative regulation of transcription from RNA polymerase II promoter inferred from direct assay (Vachon et al., 1992) open tracheal system development inferred from mutant phenotype (Guha and Kornberg, 2005) positive regulation of muscle organ development inferred from mutant phenotype (LaBeau et al., 2009) regulation of imaginal disc growth inferred from mutant phenotype (Crickmore and Mann, 2006) regulation of transcription, DNA-dependent inferred from direct assay (assigned by UniProtKB) (Ekker et al., 1991) specification of organ identity inferred from mutant phenotype (Shashidhara et al., 1999) specification of segmental identity, thorax inferred from mutant phenotype (de Navas et al., 2006)
Cellular Component
CV term Evidence References
nucleus inferred from direct assay (assigned by UniProtKB) (Ekker et al., 1991)
Terms Based on Predictions or Assertions ( 9 terms )
Molecular Function
CV term Evidence References
sequence-specific DNA binding transcription factor activity inferred from sequence or structural similarity with UniProtKB:P09629 (FlyBase, 1992-) non-traceable author statement (Swiss-Prot Project Members, 1986.7.21) traceable author statement (Gibson and Schubiger, 2001)
Biological Process
CV term Evidence References
dorsal vessel aortic cell fate commitment traceable author statement (Lo and Frasch, 2003) endoderm formation traceable author statement (Martin-Blanco, 2000) midgut development traceable author statement (Murakami et al., 1999) regulation of transcription, DNA-dependent non-traceable author statement (Swiss-Prot Project Members, 1986.7.21) regulation of transcription from RNA polymerase II promoter inferred from sequence or structural similarity with UniProtKB:P09629 (FlyBase, 1992-) specification of segmental identity, abdomen non-traceable author statement (Swiss-Prot Project Members, 1986.7.21) specification of segmental identity, thorax non-traceable author statement (Swiss-Prot Project Members, 1986.7.21, Simpson, 2002)
Cellular Component
CV term Evidence References
nucleus inferred from sequence or structural similarity with UniProtKB:P09629 (FlyBase, 1992-) non-traceable author statement (Swiss-Prot Project Members, 1986.7.21)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Ubx allele Gene References Ubx1 Gug (Kankel et al., 2004) z (Lewis, 1959) Ubx6.28 E(bx) (Badenhorst et al., 2002) Scr (Andrew et al., 1994) Ubx9.22 crn (Burnette et al., 1999) fl(2)d (Burnette et al., 1999) Hrb27C (Burnette et al., 1999) kz (Burnette et al., 1999) vir (Burnette et al., 1999) Ubx130 Trl (Farkas et al., 1994, Laney and Biggin, 1996, Schwendemann and Lehmann, 2002, Shimojima et al., 2003) Ubx195 crn (Burnette et al., 1999) fl(2)d (Burnette et al., 1999) Hrb27C (Burnette et al., 1999) kz (Burnette et al., 1999) vir (Burnette et al., 1999) Ubxabx-1 abd-A (Casares et al., 1996) Abd-B (Casares et al., 1996) ash1 (LaJeunesse and Shearn, 1995) ash2 (LaJeunesse and Shearn, 1995) Ubxabx-2 ash1 (LaJeunesse and Shearn, 1995) ash2 (LaJeunesse and Shearn, 1995) Ubxabx-CAC4 ash1 (LaJeunesse and Shearn, 1995) ash2 (LaJeunesse and Shearn, 1995) Ubxbx-1 ss (Kuzin et al., 1997) su(Ubxbx-1) (Manoukian et al., 1992) Ubxbx-3 abd-A (Casares et al., 1996) Abd-B (Casares et al., 1996) E(bx) (Lindsley and Zimm, 1992) ss (Kuzin et al., 1997) su(Hw) (Bender et al., 1983) z (Lewis, 1959) Ubxbx-8 E(bx) (Badenhorst et al., 2002) Ubxbx-9 su(Hw) (Bender et al., 1983) Ubxbx-34e ash1 (LaJeunesse and Shearn, 1995) ash2 (LaJeunesse and Shearn, 1995) DIP1 (Bondos et al., 2004) Dsp1 (Decoville et al., 2001) E(bx) (Badenhorst et al., 2002) e(we) (Rutledge et al., 1988) su(Hw) (Bender et al., 1983, Dorsett, 1993, Morcillo et al., 1996, Rollins et al., 1999) z (Lewis, 1959) Ubxbx-83Kb Dsp1 (Decoville et al., 2001) Ubxbxd-1 Hel89B (Crosby et al., 1999) Ubxbxd-51j ss (Kuzin et al., 1997) Ubxbx-G su(Hw) (Bender et al., 1983) UbxCbx-1 Pcl (Duncan, 1982) ss (Kuzin et al., 1997) Trl (Bejarano and Busturia, 2004) UbxCbx-1RM z (Micol and Garcia-Bellido, 1988) UbxCbx-2 z (Micol and Garcia-Bellido, 1988) UbxIa.Scer\UAS.T:Hsim\VP16 Antp (Li and McGinnis, 1999) Ubxlac1 abd-A (Casares et al., 1996) Abd-B (Casares et al., 1996) UbxM1 N (Florence and McGinnis, 1998) nej (Florence and McGinnis, 1998) UbxMX2 Scr (Macias and Morata, 1996) Ubxpbx-1 abd-A (Casares et al., 1996) Abd-B (Casares et al., 1996) z (Lewis, 1959) UbxScer\UAS.cCa exd (Sprecher et al., 2004) hth (Yao et al., 1999) Ubxunspecified Chi (Morcillo and Dorsett, 1996) Scr (Perrin et al., 2004) skd (Lindsley and Zimm, 1992) z (Lewis, 1959) unspecified abd-A (de Navas et al., 2006, Macias and Morata, 1996) Abd-B (Macias and Morata, 1996) Alh (Pallavi et al., 2006) Antp (Hannah-Alava, 1964, Macias and Morata, 1996) aos (Pallavi et al., 2006) ash1 (LaJeunesse and Shearn, 1995) ash2 (LaJeunesse and Shearn, 1995) Bka (Nastase et al., 2001) Dfd (Macias and Morata, 1996) Dl (Mohit et al., 2006) dpp (de Navas et al., 2006) dre4 (Shimojima et al., 2003) drl (Pallavi et al., 2006) E(bx) (Bhosekar and Babu, 1987) Egfr (Pallavi et al., 2006) hl (Ouweneel, 1970) lab (Macias and Morata, 1996) lolal (Faucheux et al., 2003) nej (Anderson et al., 2005) Nipped-B (Rollins et al., 1999) SoxN (Girard et al., 2006) su(Hw) (Lindsley and Grell, 1968, Bender et al., 1983) Syx1A (Pallavi et al., 2006) tkv (de Navas et al., 2006, Crickmore and Mann, 2006) trg (Moore et al., 1998) Trl (Faucheux et al., 2003) vn (Pallavi et al., 2006) z (Laney and Biggin, 1996)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 67078 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0003944 DroID - A comprehensive database of gene and protein interactions. • FBgn0003944 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42034
Orthologs
Genome-wide drosophilid orthologs	Dana\GF17924 Dere\Ubx Dgri\GH19471 Dmoj\GI24708 Dper\GL23004 Dpse\Ubx Dsec\Ubx Dsim\Ubx Dvir\Ubx Dwil\GK13855 Dyak\Ubx
Curated drosophilid orthologs	Camo\Ubx   Dadi\Ubx   Dafs\bx (Sturtevant and Novitski, 1941) Dana\bx   Dath\bx (Sturtevant and Novitski, 1941) Dbus\Hr   Dbuz\Ubx   Deug\Ubx (Dellino, 2001.10.25) Dfun\Ubx   Dhet\Ubx   Dhyd\Ubx   Dpiv\Ubx   Dpse\Ubx (Sturtevant and Novitski, 1941, Sturtevant and Tan, 1937) Drep\Ubx   Dsim\Ubx   Dvir\Ubx (Lewis et al., 2003) Dwil\bx (Spassky and Dobzhansky, 1950) Spat\Ubx   Zvit\Ubx
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL010298-PA Aedes aegypti (mosquito) AAEL014032-PA Aedes aegypti (mosquito) AGAP004661-PA Anopheles gambiae (mosquito) XP_623989.2 Apis mellifera (honey bee) XP_001944459.1 Acyrthosiphon pisum (pea aphid) BGIBMGA006389-PA Bombyx mori (silk worm) ENSBTAP00000005650 Bos taurus (bovine) CE27837 Caenorhabditis elegans (worm) ENSCAFP00000019812 Canis familiaris (dog) CPIJ001012 Culex pipens (mosquito) ENSCPOP00000013524 Cavia porcellus (guinea pig) RP29419 Caenorhabditis remanei (nematode) 225442 Capitella spl (polychaete worm) ENSDARP00000076765 Danio rerio (zebra fish) ENSMODP00000000552 Monodelphis domestica (gray opossum) XP_001603621.1 Nasonia vitripennis (wasp) PHUM002157-PA Pediculus humanus (human body louse) ENSPPYP00000014467 Pongo pygmaeus (orangutan) ENSPTRP00000021642 Pan troglodytes (chimpanzee) XP_780219.1 Strongylocentrotus purpuratus (purple sea urchin) NP_001034497.1 Tribolium castaneum (red flour beetle)
Stocks & Reagents
Stocks Listed in FlyBase ( 250 )
Bloomington	3197 Ubxbxd-1 457 Ubxbx-34e 3475 Ubx51/TM1 3428 Ubxbxd-266 3421 Ubxbx-8/TM1 3413 Ubxabx-1/TM1 8617 Ubxpbx-2/TM1 3437 Ubxbx-34e/TM1
Kyoto	106910 Ubxbxd-1 105920 Ubxbx-34e 107040 Ubxbx-34e/TM1 107035 Ubxabx-1 / TM1
	More stocks available...
Genomic Clones ( 2 )
	BACR28H01 BACR48L13 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 61 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD09363 RE43738
Other clones	DPiM_RE43738
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LD41826 LP15120 RE46542 RE71819
Other clones	8874 14548 35493 37439.2 42388 57126 63484 80743 119377 176790 214345.37 214381.38 214471.33 273555 475301 CK01.10A.A4 CK01.21D.G1 CK01.39B.H5 CK01.61A.D12 CK01.75C.D7 CK01.93C.A4 CK01.99C.D6 CK01.102B.G5 CK01.132A.D2 EK020219 EK049458 EK058157 EK063846 EK072934 EK084347 EK086127 EK108158 EK117325 EK155715 EK157028 EK170414 EK189440 EK213843 EK238919 EK300621 EP01057 EP02129 FGM222E05 FGM303A08 RP004040053 RP004050735 RP004099119 RP004163275 RP004261076 RP004261170 RP004399703 RP004406656 RP004436682 RP004451878
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0003944 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42034
Antibody Information
	monoclonal (Hudry et al., 2011)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Ubx CG10388 (Zhong, 1999.11)
Source for database merge of
Additional comments	Comparison of the activity of ectopic Ubx and Akap\Ubx in Drosophila suggests that Ubx and Akap\Ubx are functionally interchangeable. (Grenier and Carroll, 1998)
Other Comments
	During embryonic development Ubx produces mRNAs with distinct 3' UTRs that harbour different sets of miRNA targets in different tissues. The differential distribution of Ubx mRNAs bearing specific 3'UTR sequences is established independently of miRNA regulation, indicating that it is not the result of miRNA-mediated transcript degradation but instead the consequence of an "in-built" RNA processing system that remodels Ubx 3'UTRs according to developmental context. (Thomsen et al., 2010) The Ubx and dpp products collaborate to repress the tkv repressor, sbb, in the haltere disc. The resulting increased amounts of tkv receptor decrease dpp mobility in the haltere. (Crickmore and Mann, 2006) The Ubx protein binds to cis-regulatory regions of the Egfr gene. (Pallavi et al., 2006) The QA motif is preferentially required for repression of postnotal tissue. (Hittinger et al., 2005) The Ubx 3'UTR contains predicted target sites for the mir-iab-4 5p microRNA. (Ronshaugen et al., 2005) Ternary complex formation can occur between UbxIb protein, DIP1-c protein and Ubx target DNA. (Bondos et al., 2004) Ubx modulates the shape and size of the third leg by a range of both cell autonomous and non-autonomous mechanisms, and is required at different times. (Stern, 2003) Epigenetic activation of Ubx transcription coincides with trivalent methylation by ash1 and recruitment of brm. (Beisel et al., 2002) Ubx is required to confer an aorta identity on cardiomyocytes in the developing embryo. (Ponzielli et al., 2002) Ubx blocks the development of apical and sternopleural bristles on the T3 leg. (Rozowski and Akam, 2002) Ubx protein present before pupation is sufficient to control the normal differences in behaviour that distinguish wing and haltere cells much later, between 24 and 48 hours after puparium formation. (Roch and Akam, 2000) vir and fl(2)d are required for inclusion of mI and mII microexons in Ubx mRNAs. Hrb27C plays a critical role in the inclusion of mI and mII microexons in Ubx mRNAs. (Burnette et al., 1999) The modulation of Hox gene activation and repression functions can account for segment-specific morphological differences. (Li and McGinnis, 1999) Ubx has distinct spatial roles during maintenance of cell fate and patterning in the halteres. (Shashidhara et al., 1999) Expression of Ubx in the haltere D/V boundary down-regulates its D/V organizer signalling compared to that of the wing D/V organizer. (Shashidhara et al., 1999) In the antennal disc, Ubx exerts its effects by suppressing the transcription of hth and thus preventing the nuclear localisation of exd. (Yao et al., 1999) Subcellular localisation of exd is regulated by the bithorax complex genes and each the bithorax complex gene can prevent or reduce nuclear translocation of exd to different extents. Ubx and abd-A require exd activity for their maintenance and functions. (Azpiazu and Morata, 1998) Whenever a Hox gene functions as a repressor in the dpp enhancer it prevails over others that function as activators. (Capovilla and Botas, 1998) Asx is required in the central nervous system to regulate Ubx. (Sinclair et al., 1998) The detailed regulation of Ubx patterns trichomes on the posterior femur of the second leg. Evolution of this regulation has contributed to divergence among closely related species. (Stern, 1998) Transcriptional activation of Ubx is subject to competition between dpp-activated Mad and another Smad whose function as a transcriptional repressor depends on high wg signalling. (Yu et al., 1998) Ras85D+ activity modulates Ubx function. (Boube et al., 1997) The Ubx promoter and nearby sequences are not required to establish a normal late embryonic pattern. (Casares et al., 1997) Binding of z protein to either the proximal enhancer of Ubx or to the BXD enhancer element of Ubx does not require the presence of the other element. However, significant transcription is observed only when both elements are present and bound by z. (Laney and Biggin, 1997) Formation of the Ubx HD-DNA complex is associated with significantly greater water release than that of the Dfd HD-DNA complex. No influence of pH in water release was detected for either homeodomain. Chimeric Ubx-Dfd homeodomains demonstrates the C terminal region of the Ubx HD is the primary determinant for the greater water release associated with DNA binding for the protein. (Li and Matthews, 1997) A wg response sequence (WRS) is identified in the visceral mesoderm enhancer from Ubx. WRS is a binding site for Mmus\Lef1. Mmus\Lef1 can form a stable complex with arm protein on the Ubx WRS and function in vivo depends on arm. The ability of Mmus\Lef1 to stimulate transcription requires dpp signalling, implying Mmus\Lef1 has a crucial function in coordinating multiple signalling inputs. (Riese et al., 1997) A wg response sequence (WRS) has been identified in the visceral mesoderm enhancer from Ubx. (Riese et al., 1997) The Pc protein is not distributed homogeneously on the regulatory regions of the repressed Ubx and abd-A genes, but is highly enriched at discrete sequence elements, many of which coincide with previously mapped Pc response elements (PREs). (Strutt et al., 1997) Ubx 5' UTR contains an internal ribosome entry site (IRES). The IRES exhibits a high degree of developmental regulation. (Ye et al., 1997) Ectopic expression of Ubx, abd-A and Abd-B cause similar transformations in the appendages (antenna and wing) but different transformations in the main body axis. abd-A, and to some extent Abd-B, can form haltere-like tissue in the absence of Ubx. Although exd product affects wing development the presence of exd fails to modify the wing to haltere transformation caused by ectopic expression of either Ubx or abd-A. (Casares et al., 1996) Flies have been artificially selected for differential sensitivity to the induction of bithorax phenocopies by ether vapour. (Gibson and Hogness, 1996) Increased sensitivity to ether correlates with loss of expression of Ubx in the third thoracic imaginal discs. (Gibson and Hogness, 1996) Transvection effects have been analysed in terms of rates of transcription from both Ubx homologues in various combinations. The results suggest that transvection is not simply a case of the enhancer of one homologue regulating transcription of the other homologue, but indicate a more complex level of trans regulation that may have implications for the aetiology of genetic disorders that are influenced by chromosome rearrangements. (Goldsborough and Kornberg, 1996) Despite the absence of a syncytium in C.floridanum embryos monoclonal antibodies to en, Ubx and abd-A demonstrate their cognate proteins are expressed in a conserved pattern in the post-gastrulation stages of development. The expression of the eve cognate protein is not completely conserved and lacks a pair rule phase to its expression. (Grbic et al., 1996) The Ubx gene has redundant cis-regulatory elements, which apparently contain binding sites for factors that share the function of the z gene product. z and Trl have an overlapping function in regulating Ubx. The z product binds at equal levels to Ubx promoter constructs (which it activates) as to the endogenous Ubx gene (which it redundantly regulates). (Laney and Biggin, 1996) DNA binding properties of Ubx and Dfd homeodomains are differentially influenced by alterations in physical environment. (Li et al., 1996) bxd alleles of Ubx partially rescue the adult mutant phenotypes of bx Ubx alleles. These results suggest that the bxd region contains a negative cis-regulatory element involved in the control of the activity of the Ubx gene in the T3a compartment. (Martinez-Laborda et al., 1996) Chi, but not mam, modulates expression of a gypsy insertion into Ubx. (Morcillo et al., 1996) Expression of the 2218R6 enhancer element, found in the bxd region, begins after gastrulation and is dependent on wg. H1 and H3 elements are only activated in the later embryo and direct expression in the imaginal discs. (Poux et al., 1996) The temporal pattern of Ubx expression is critical for the different functions of Ubx in the abdomen (suppressing limb formation) and in the thorax (modifying leg development). (Castelli-Gair and Akam, 1995) The regulatory sequences in the Ubx promoter have been mapped to a 440bp region. The Ubx proximal promoter is essential for trx-dependent activation. (Chang et al., 1995) Pc associates with multiple sites in the bithorax complex and these sites all contain maintenance element. (Chiang et al., 1995) At the locations of the first and third constrictions, opa is negatively regulated by Ubx and dpp. (Cimbora and Sakonju, 1995) Function of Ubx is mediated by that of exd in the metanotum, but not in the appendage portion of the segment. In the absence of exd, Ubx and abd-A have equivalent roles in abdominal tergites 1-4. (Gonzalez-Crespo and Morata, 1995) Ubx expression can induce gonad formation. (Greig and Akam, 1995) The trx and fs(1)h proteins can function independently as activators of the Ubx locus. (Huang et al., 1995) Highly selective interactions exist between exd and certain isoforms of Ubx and with the abd-A protein. The Ubx sequences critical for the interaction have been mapped to the homeodomain and a 15 residue N-terminal extension of the homeodomain that includes the YPWM sequence. The region between the homeodomain and YPWM influences the interaction. (Johnson et al., 1995) The transcription unit that produces the noncoding bxd transcript has been identified. (Lewis et al., 1995, Martin et al., 1995) Ubx fragments that bind hb protein in vitro contain parasegmental enhancers active in the embryo in specific parasegmental patterns. Three new embryonic enhancer elements have been defined. Imaginal disc expression of Ubx is not determined by the embryonic enhancers but by a distinct set of imaginal disc enhancers. They are active in thoracic and head imaginal discs. Positional information is conveyed to them through the Pc-group response element, which in turn depends on the state of activity of the parasegmental enhancers. (Pirrotta et al., 1995) Ubx protein directly regulates dpp expression. At least one other activity, possibly exd, is required in conjunction with Ubx for PS7-specific activation. (Sun et al., 1995) The Pc response element, or PRE, of Ubx is a complex site, subfragments of which retain some independent activity. These subfragments are targets for different components of the trx-G of Pc-G genes and are not simply reiterated targets for the same complex. (Tatout et al., 1995) Ubx has no effect on the ability of Scr to direct the formation of salivary glands. (Andrew et al., 1994) Heat shock induced expression of mouse Hox genes in Drosophila embryos deficient for homeotic genes demonstrates that functional hierarchy is a universal property of the homeobox genes. Correlations exist between the expression patterns of the mouse Hox genes along the antero-posterior body axis of mice and the extent of their effect along the antero-posterior body axis of flies. (Bachiller et al., 1994) Ubx expression in the ectoderm and mesoderm of the posterior abdomen is regulated by co-operative cis regulatory elements. At least some of these regulatory elements are germ layer specific and not parasegment specific. (Camprodon and Castelli-Gair, 1994) The dpp gene has a visceral mesoderm-specific enhancer that is regulated by Ubx and abd-A in vivo. (Capovilla et al., 1994) The region -20 to -30kb upstream of the Ubx promoter carries an element the responds to the Pc group genes, this forms a complex with products of the Pc group genes and is able to maintain the repressed state of enhancers present in its vicinity throughout development. This regulatory element is called the Pc-G response element of PRE. (Chan et al., 1994) Cooperative interactions between Ubx protein and exd protein selectively increase the affinity of Ubx for a particular DNA target. Both the Ubx homeodomain and the Ubx C-tail are important for the in vitro interaction with exd protein. (Chan et al., 1994) Two types of silencers restrict the activity of imaginal disc enhancers from Ubx to the Ubx domain in imaginal discs; embryonic silencers with hb protein binding sites and at least one silencer (BXD) which lacks such sites. Silencing by BXD requires Pc. Silencing in imaginal discs requires cooperation between hb and Pc target sites within the two types of silencers. (Christen and Bienz, 1994) Antp, Ubx and Dfd protein homeodomain regions bind preferentially to a core sequence which differs from the binding sequence of Abd-B. N-terminal amino acid differences are responsible for the sequence specificity difference between Abd-B and Ubx. Antp and Ubx homeodomains display indistinguishable preferences outside the core, while Ubx differs. (Ekker et al., 1994) en-mediated repression of Ubx is necessary for the parasegment 6 identity. (Mann, 1994) Antp, Ubx, abd-A, dpp and wg are required for proper tsh expression. The control of tsh by Ubx, abd-A and probably also by Antp is mediated by secreted signalling molecules. (Mathies et al., 1994) Ubx and abd-A have equivalent functions in promoting the formation of particular muscle precursors in the abdominal segments, while Abd-B suppresses these same myogenic cells in the posterior region of the abdomen. Either Ubx or abd-A can override the inhibitory effect of Abd-B, when expressed in the same mesodermal cells. Homeotic cues specific to both the mesoderm and ectoderm cooperate to specify the pattern of muscle attachment sites. (Michelson, 1994) Ubx and abd-A are required for the expression of the abdominal variant of the NB1-1 lineage. (Prokop and Technau, 1994) Homeoproteins Ubx and abd-A act through the same downstream element to differentially regulate Antp P1 promoter activity. (Saffman and Krasnow, 1994) Ectopic expression of dpp eliminates Scr and Antp expression, attenuating abd-A expression, inducing Ubx, dpp, wg and tsh expression in the visceral mesoderm and inducing lab expression in the apposing endoderm. (Staehling-Hampton and Hoffmann, 1994) The exd protein raises the DNA binding specificity of Ubx and abd-A protein, but not that of Abd-B. (van Dijk and Murre, 1994) In vivo crosslinking studies demonstrate that endogenous z protein interacts directly with the Ubx promoter. (Walter et al., 1994) Ubx is required for nub repression in the central domain of the embryonic midgut. (Affolter et al., 1993) 30 common binding sites for Ubx and abd-A product have been identified in the Antp P2 promoter. Different mechanisms of repression of Antp by Ubx and abd-A product operate in different tissues. (Appel and Sakonju, 1993) Naturally occurring binding sites for the Ubx protein contain multiple, individual recognition sequences. Ubx protein complexes are progressively stabilised by increasing numbers of individual recognition sequences. This cooperative stabilisation can extend to sites separated by as much as 200bp. Cooperative binding requires amino acid sequences outside the homeodomain. (Beachy et al., 1993) trx exerts its effects by positively regulating homeotic gene expression, but Ubx, Antp, abd-A, Abd-B, Scr and Dfd have different tissue-specific, parasegment-specific and promoter-specific reductions in expression in a trx mutant background. (Breen and Harte, 1993) The homeobox domains and residues carboxy-terminal to the homeo domain (C-tail) contribute to the functional specifications between Ubx and Antp gene products. (Chan and Mann, 1993) Ubx autoregulation in parasegment 7 of the visceral mesoderm may be indirect. Ubx reporter gene expression in the visceral mesoderm is coincident with and requires dpp. (Hursh et al., 1993) Positive autoregulation of Ubx is restricted to the visceral mesoderm, while in other tissues Ubx negatively autoregulates. The upstream control region of Ubx contains multiple regulatory elements for both positive and negative autoregulation. (Irvine et al., 1993) There is a strong correlation between chromosomal location of breakpoint or insertional mutation at Ubx and clustering of S1 nuclease sensitive sites. Prominent S1 sites colocalise with unusual DNA sequences and transcription factor(s) putative binding sites. (Martin-Blanco et al., 1993) In the absence of the bithorax complex, Scr is derepressed in the posterior compartments of the thorax and abdomen, but only in the epidermis. (Pelaz et al., 1993) The core activity of the BRE (bithorax region enhancer) of Ubx is included within a 500 bp module. This region includes binding sites for hb, ftz, tll, en and twi. The binding of their products and the interplay between them is responsible for generating the expression pattern directed by the BRE. (Qian et al., 1993) The exd gene product acts with the selector homeodomain proteins, including Ubx, as a DNA binding transcription factor, thereby altering their regulation of downstream target genes. exd alters the segmental morphology specified by Ubx via its homeodomain or C terminus, and not the N terminus. (Rauskolb et al., 1993) Transformed metathorax of Ubx adult mutants has a functional, duplicated neural pathway for the escape-jump response. That transformation of the corresponding flight muscles is rare indicates that the presence of a motor neuron is not always sufficient to induce or determine the development of its target muscle. (Schneiderman et al., 1993) The bithorax complex genes are regulated by the Pc group of genes, acting via 'Pc group response elements' (PREs), that can work even when removed from the normal the bithorax complex context. (Simon et al., 1993) The upstream sequence of Ubx contains separate response elements for dpp and wg which function independently in the visceral mesoderm, though both positive and negative interactions take place between them. (Thuringer et al., 1993) Positive autoregulation of Ubx is at least partly indirect and is mediated by the extracellular signal molecules encoded by dpp and wg: indirect autoregulatory mechanisms may be used to ensure coordinate maintenance of selector gene activity in groups of cells. (Thuringer and Bienz, 1993) The first Ubx splicing event is cotranscriptional. (Artero et al., 1992) Redundant or cooperatively acting sequences are required for Ubx gene expression in the anterior compartment of the first abdominal segment, and the expression of Ubx in the posterior compartment of the third thoracic segment is modulated by positive and negative cis-regulatory elements. (Castelli-Gair et al., 1992) Ubx homeodomain binds optimally to a distinct DNA sequence. (Ekker et al., 1992) Different homeotic genes have specific local effects on Dfd expression. (Gonzalez-Reyes et al., 1992) The Con gene is a binding site for Ubx in vivo. (Gould and White, 1992) Over-expression of Ubx extends the βTub60D expression domain. (Hinz et al., 1992) In vitro studies showed that Ubx and eve protein exert active and opposite effects on in vitro transcription when bound to a common site upstream of a target (Adh) core promoter: Ubx acts as an activator and eve acts as a repressor, and both affect the extent of preinitiation complex formation. (Johnson and Krasnow, 1992) DNaseI footprinting analysis reveals core histones His2A, His2B, His3 and His4 (but not His1) bind to the Ubx minimal enhancer element in a periodic manner. (Kerrigan and Kadonaga, 1992) The gene products of Abd-B and Ubx compete for the specification of segmental identities in a dose-dependent fashion, supporting a quantitative competition model rather than strict functional hierarchy for their cross-regulatory interactions. (Lamka et al., 1992) Ectopic Ubx affects abdominal cuticular identities if expressed during the early stages of embryogenesis. In later stages abdominal segments become resistant to transformation by ectopic Ubx while thoracic segments remain susceptible. (Lamka et al., 1992) Analysis of Dfd-Ubx chimeric coding regions identifies specific amino acid residues at the amino end of the Ubx homeo domain that are required to specifically regulate Antp transcription. In the context of Dfd protein, these amino-end residues are sufficient to switch from Dfd- to Ubx-like targeting specificity. (Lin and McGinnis, 1992) Ubx is a member of the bithorax complex. The bithorax complex is a gene cluster that functions to assign unique identities to body segments in the abdomen and posterior thorax. Most, perhaps all, the bithorax complex functions are expressed within parasegments, metameric units composed of the posterior compartment of one segment and the anterior compartment of another. Complementation studies indicate that the bithorax complex is organized into three large functionally integrated regions, known as the Ultrabithorax (Ubx), abdominal-A (abd-A), and Abdominal-B (Abd-B) domains. The Ubx domain functions primarily to assign identities to parasegments 5 and 6. (Lindsley and Zimm, 1992) Mutations in Ubx fall into several classes including the bithorax (bx), bithoraxoid (bxd), anterobithorax (abx), postbithorax (pbx), Contrabithorax (Cbx) classes. Ubxabx-1 homozygotes show variable transformations of the anteriormost portion of the third thoracic segment (T3) toward the corresponding part of T2. Homozygotes also show variable transformations of posterior T2 to posterior T1. The latter effect is enhanced by low temperature. Ubxabx-1 partially complements and shows transvection with Ubxbx-1, Ubxbx-3 and Ubxbx-34e. Ubxabx-1/Ubxpbx-1 has the posterior portion of the distal segment of the haltere very slightly transformed into wing tissue; Ubxabx-1/Ubxpbx-2 is similar if heterozygous for a rearrangement that suppresses transvection. Ubxbx-1 homozygotes have anterior portion of third thoracic segment (T3) transformed toward corresponding region of second (T2). The extent of this transformation is allele-dependent and is most extreme in Ubxbx-3 and weakest in Ubxbx-4. Although the transformations caused by most bithorax alleles are uniform, those caused by Ubxbx-1 and Ubxbx-34eprv are highly variable. At 17oC several bithorax alleles show weak and variable transformations of posterior T2 to posterior T1. Ubxbx-3, Ubxbx-8 and Ubxbx-G over Ubxpbx-1 show a very slight Ubxpbx-1 effect (as described for Ubxabx-1) if heterozygous for a rearrangement that suppresses transvection. Ubxbxd-1 homozygotes show transformation of the anterior first abdominal segment (A1) to the corresponding region of the third thoracic segment (T3). In addition, Ubxbxd-1 homozygotes have posterior T3 and posterior A1 transformed toward posterior T2. Hemizygotes for the stronger bithoraxoid alleles show (with variable expression) formation of one or a pair of well-developed thoracic legs and, rarely, an extra haltere on A1; the frequency of these abdominal halteres is greatly enhanced in hemizygotes for Ubxbxd-9 abd-Aiab2-K. The A1 legs in Ubxbxd-1 hemizygotes contain underdeveloped posterior compartments, indicating that posterior A1 is partially transformed toward thorax. UbxCbx-1/+ has a strong transformation of the posterior region of the second thoracic segment (T2) toward the corresponding region of the third (T3) and a weak and variable transformation of anterior T2 toward anterior T3. The UbxCbx-1 homozygote differs in having a stronger, but still variable, transformation of anterior T2 toward T3. UbxCbx-1/Ubx has a slight enhancement of the Ultrabithorax phenotype (see also su(Cbx)). UbxCbx-2 has both anterior and posterior regions of T2 moderately transformed toward T3. UbxCbx-Hm affects only the wing, which is strongly transformed to haltere. Flies carrying two doses of UbxCbx-Hm plus a normal allele have a virtually complete transformation of wing to haltere. UbxCbx-2 and UbxCbx-Hm have inseparable recessive bithoraxoid effects. UbxCbx-3/+ transforms anterior portions of T2 variably toward anterior T3. It has no effect in posterior T2. For an overview of the effects of UbxCbx-1 mutants on specific structures see Table 1 of Adult Ubxpbx-1 homozygotes and hemizygotes have posterior region of third thoracic segment (T3) transformed toward corresponding region of the second (T2). Larvae homozygous and hemizygous for strong Ubx mutants, such as the Ubx1-type, have the ventral setal bands or 'hooklets' of the first abdominal segment (A1) and T3 transformed toward those of T2; dorsally, the hair patterns of posterior T2 and posterior T3 are transformed toward posterior T1; Keilin organs with 2 hairs appear on A1; ventral pits appear on segments A1 through A7; two extra sets of anterior spiracles appear, one on T3 and one on A1. Homozygotes die, usually as tiny third instar larvae, but occasionally grow to a normal-sized third instar larvae and may pupate. Homozygotes of some weaker alleles, such as Ubx61d, survive to adult stage and show weak bithorax, bithoraxoid and postbithorax effects, especially in the haltere and A1 is generally reduced. (Lindsley and Zimm, 1992) ftz protein acts directly as a transcriptional activator of Ubx. Some ftz binding sites are adjacent to, and some overlap, hb binding sites in the Ubx promoter, suggesting that ftz protein competes with hb protein for DNA binding and/or transcriptional activation of Ubx, to produce the sharp anterior boundary to Ubx expression. (Muller and Bienz, 1992) Ectopic uniform wg expression causes Ubx expression to be high in those cells not expressing en (which are fewer than in wild type due to the expansion of the en domain). (Noordermeer et al., 1992) Ubx down-regulates Pc. (Paro and Zink, 1992) Antp and Ubx act independently of tsh for the determination of trunk identity. (Roder et al., 1992) Ubx derepression by Pc mutants causes haltere to wing transformations. (Tamkun et al., 1992) In embryos mutant at Ubx, abd-A and Abd-B, Dll expression is derepressed in the abdominal segments. (Vachon et al., 1992) hb gene product acts directly to repress Ubx mediated activity. (Zhang and Bienz, 1992) trx is necessary for normal levels of Ubx protein accumulation. (Breen and Harte, 1991) In Ubx mutant embryos both Dll and disco are ectopically expressed in parasegment 6 and this expression correlates with the ectopic development of a Keilin's organ. (Cohen et al., 1991) Dfd and Ubx transcript patterns remain unaltered in tsh- embryos. (Fasano et al., 1991) Ubx plays a role in the formation of imaginal histoblast cells. (Frayne and Sato, 1991) The upstream control region of Ubx is extraordinarily long, and upstream control region functions are effected through transcriptional regulation of Ubx. (Irvine et al., 1991) The bxd region does not cis-regulate abd-A. (Mathog, 1991) Three Ubx key control regions, PBX, ABX and BXD confer an expression pattern mimicking certain aspects of Ubx expression. The boundaries of expression imposed by PBX or ABX on the BXD pattern are dependent on Pc function. PBX and ABX are recognized by repressors which act across large distances to suppress BXD activity. (Muller and Bienz, 1991) Mutations in zygotic homeotic gene Ubx do not interact with RpII140wimp. (Parkhurst and Ish-Horowicz, 1991) The bx region contains a spatially regulated enhancer element, BRE. The imaginal function of bx requires the interaction of the BRE with other control elements to produce the correct pattern in the haltere and third leg discs and to repress the expression in discs more anterior than parasegment 5. The BRE element is regulated by hb. (Qian et al., 1991) Homeotic gene activity programs primordia as either discs or histoblast nests by the early extended germ band stage. (Simcox et al., 1991) hb protein directly binds to the PBX control region of Ubx and acts as a repressor to specify the boundary positions of the PBX pattern. (Zhang et al., 1991) Homeotic gene products can be ectopically expressed in regions where they are normally down regulated causing no phenotypic consequence in the epidermis. (Gonzalez-Reyes et al., 1990) Ubx, Kr and eve expression are altered in fs(1)h mutant embryos. (Huang and Dawid, 1990) Ubx, abd-A, dpp, wg and lab have interacting gene products involved in the induction process between the visceral mesoderm and the gut epithelium in the embryo. (Immergluck et al., 1990) Ubx expression is unaffected in lab mutants. (Immergluck et al., 1990) E(z)+ activity is required not to initiate the expression patterns of Scr and Ubx, but to maintain their repressed state. (Jones and Gelbart, 1990) In abd-A- embryos the posterior compartment shows high levels of Ubx activity and variations in the amount of product in the anterior. (Macias et al., 1990) In the absence of endogenous Ubx ectopic expression of Ubx can still specify parasegment 6. (Mann and Hogness, 1990) Ectopic expression of Ubx causes homeotic transformation in the embryo and adult. (Mann and Hogness, 1990) The C terminal homeodomain portion of Ubx is needed to generate the transformation phenotype. (Mann and Hogness, 1990) Ubx mutants have been classified into "transvection groups". (Mathog, 1990) Mutants in the shv region of dpp reduce the Ubx expression domain and the level of Ubx protein in the midgut. (Panganiban et al., 1990) Mutations in Ubx and exd are additive in phenotype. Ubx acts in its proper domain in an exd mutant but the morphological consequences of Ubx expression are altered. (Peifer and Wieschaus, 1990) Spatially restricted expression of dpp in the visceral mesoderm is regulated by the homeotic genes Ubx and abd-A. Ubx induces dpp expression in the visceral mesoderm cells of the anterior midgut. (Reuter et al., 1990) Antp is regulated in the visceral mesoderm by the homeotic gene Ubx. (Reuter and Scott, 1990) A regulatory element in the abx region programs Ubx expression with a proper anterior limit in parasegment 5 and a regulatory element in the bxd region programs proper anterior limit in parasegment 6. (Simon et al., 1990) An interaction between Ubx+ and Antp establishes segmental identity in pT2. (Smolik-Utlaut, 1990) A unique combination of gap genes and pair rule genes is required for the initial activation of Ubx and Antp promoters in the embryo. (Irish et al., 1989) Ubx proteins are transcriptional repressors and activators whose action is mediated by binding to promoter region sequences. Ubx proteins may have a modular design similar to other transcriptional regulators. (Krasnow et al., 1989) The role of the homeodomain in determining target specificity has been tested by replacing the homeobox of Dfd with that of Ubx. The resulting chimeric protein cannot activate transcription from Dfd but can activate ectopic transcription of Antp, a gene normally regulated by Ubx. (Kuziora and McGinnis, 1989) The position of the Ubx expression domains in the visceral mesoderm have been defined with respect to parasegment boundaries. (Tremml and Bienz, 1989) The homeodomain proteins encoded by Antp::Ubx can specifically activate transcription of certain promoters by acting upon a common sequence to modulate gene transcription. (Winslow et al., 1989) Regulatory activities of Ubx are direct and are mediated by binding of Ubx protein to promoter region sequences. (Beachy et al., 1988) Ubx Ib protein is a sequence-specific DNA-binding protein. Ib protein binds tightly to sequences near to its own promoter and near the P1 promoter of Antp. Binding sites occur in clusters downstream of the Ubx transcription start site and far upstream of the Antp P1 transcription start site. (Beachy et al., 1988) The correct expression of Ubx in the visceral mesoderm is dependent both on autocatalysis and on repression by abd-A. (Bienz and Tremml, 1988) The Trl product activates Ubx transcription selectively in a reconstituted in vitro reaction. (Biggin and Tjian, 1988) In the absence of the bithorax complex genes, Pc- clones develop prothoracic patterns: Scr activity overrules Antp. Adding contributions of Ubx, abd-A and Abd-B results in thoracic or abdominal patterns. (Busturia and Morata, 1988) Scr and en are derepressed in the absence of Pc and the bithorax complex function. (Busturia and Morata, 1988) Genetic analysis of transvection effects suggests that the transcription of UbxCbx-1RM and UbxCbx-2 alleles depends on RNAs of short radius of action from the homologous Ubx gene. (Micol and Garcia-Bellido, 1988) Genetic combinations of different doses of Pc and Ubx have phenotypes resulting from ectopic derepression of posterior selector genes repressing selector genes of anterior segments. (Capdevila et al., 1986) Pc+ products regulate the expression of the Ubx protein coding region. (Capdevila et al., 1986) Ubx is required in the metathorax to specify meta- as opposed to mesothoracic development. Ubx, Antp and Scr act in combinatorial fashion to specify segmental determination and have regulatory roles in controlling the selective expression of other genes. (Struhl, 1982) Mutant individuals display enlarged halteres. (Duncan and Kaufman, 1975)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_080500 NM_080504 NM_169728 NM_169729 NM_169730 NM_206497 RefSeq (Proteins) • NP_536748 NP_536752 NP_732171 NP_732172 NP_732173 NP_996219 DDBJ / EMBL / GenBank • AAA28615 AAA29008 AAA84408 AAA84409 AAA84410 AAA84411 AAA84412 AAF55355 AAF55356 AAN13717 AAN13718 AAN13719 AAQ23559 AAS65158 BI357303 BT010241 CAA29008 CAA29009 CAA29194 CAA53803 CZ471499 CZ471573 CZ489950 CZ489951 K01959 K01963 L32205 L32750 L48177 M23335 M23336 M23337 M24609 U31961 X05427 X05723 X05724 X05725 X05726 X05727 X67586 X76210 Entrez Gene - A searchable database of RefSeq genes. • 42034 UniProtKB/Swiss-Prot • P83949
Other Crossreferences
	EPD - Eukarytoic Promoter Database, an annotated collection of POL II promoters • 17017 InterPro domains - A database of protein families, domains, and functional sites • Homeobox, conserved site (IPR017970) Homeobox (IPR001356) Homeobox protein, antennapedia type, conserved site (IPR001827) Homeodomain-like (IPR009057) Homeodomain-related (IPR012287) Homeobox, eukaryotic (IPR020479) PDB - Protein Data Bank. An information portal to biological macromolecular structures • 1B8I
Linkouts
	BioGRID - A database of protein and genetic interactions • 67078 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0003944 DroID - A comprehensive database of gene and protein interactions. • FBgn0003944 DRSC - Results from RNAi screens. • FBgn0003944 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0003944 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10388-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0003944 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42034 InParanoid A subset of ortholog calls from InParanoid. • AAEL010298-PA Aedes aegypti (mosquito) AAEL014032-PA Aedes aegypti (mosquito) AGAP004661-PA Anopheles gambiae (mosquito) XP_623989.2 Apis mellifera (honey bee) XP_001944459.1 Acyrthosiphon pisum (pea aphid) BGIBMGA006389-PA Bombyx mori (silk worm) ENSBTAP00000005650 Bos taurus (bovine) CE27837 Caenorhabditis elegans (worm) ENSCAFP00000019812 Canis familiaris (dog) CPIJ001012 Culex pipens (mosquito) ENSCPOP00000013524 Cavia porcellus (guinea pig) RP29419 Caenorhabditis remanei (nematode) 225442 Capitella spl (polychaete worm) ENSDARP00000076765 Danio rerio (zebra fish) ENSMODP00000000552 Monodelphis domestica (gray opossum) XP_001603621.1 Nasonia vitripennis (wasp) PHUM002157-PA Pediculus humanus (human body louse) ENSPPYP00000014467 Pongo pygmaeus (orangutan) ENSPTRP00000021642 Pan troglodytes (chimpanzee) XP_780219.1 Strongylocentrotus purpuratus (purple sea urchin) NP_001034497.1 Tribolium castaneum (red flour beetle) Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /segment/ultrabt1.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42034 modMine - Data generated by the modENCODE project. • FBgn0003944 REDfly - A database of transcriptional regulatory elements. • FBgn0003944
Synonyms & Secondary IDs ( 32 )
Reported As
Symbol Synonym	abx (Lindsley and Zimm, 1992, Palka, 1993, Bender et al., 1985, Bender et al., 1983, Davis et al., 2007, Wong and Merritt, 2002, Merritt and Whitington, 2002) bx (Crow and Bender, 2004, Gerasimova et al., 2000, Lupo et al., 1999, Rijli et al., 1998, Lewis, 1998, Garcia-Bellido, 1998, Lawrence, 1998, Lewis, 1994, Kingston et al., 1996, Patterton and Wolffe, 1996, Lindsley and Zimm, 1992, Ashburner, 1993, Martinez Arias, 1993, Ouweneel, 1970, Lewis, 1959, Palka, 1993, Tartof and Henikoff, 1991, Dorsett, 1990, Hoshizaki et al., 1987, Bender et al., 1985, Bender et al., 1983, Kuhn and Woods, 1982, Duncan and Kaufman, 1975, Hannah-Alava, 1964, Duncan and Celniker, 2004, Phinchongsakuldit et al., 2004, Wong and Merritt, 2002) bxD   BX-C (Zhimulev and Belyaeva, 2003, Maeda and Karch, 2006, Akbari et al., 2006) bxd (Crow and Bender, 2004, Lindsley and Zimm, 1992, Duncan and Celniker, 2004, Akbari et al., 2006, Sipos et al., 2007, Phinchongsakuldit et al., 2004, Wong and Merritt, 2002, Merritt and Whitington, 2002) bxdD   Bxl (Crow and Bender, 2004) bxl   Cbx (Micol and Garcia-Bellido, 1988, Garcia-Bellido, 1998, Lindsley and Zimm, 1992, Bender et al., 1985, Bender et al., 1983, Bownes and Roberts, 1981, Duncan and Celniker, 2004, Hartl et al., 2008, Davis et al., 2007) CG10388 (Kreiman, 2004, Perkins et al., 2009, Ni et al., 2011.7.19) DmUbx (Ronshaugen et al., 2002, Grenier and Carroll, 1998, DeSalle et al., 2003) Dm Ubx (Liu et al., 2006) DUbx (Galant and Carroll, 2002) Hm (Lindsley and Zimm, 1992, ) l(3)89Eb   pbx (Rijli et al., 1998, Garcia-Bellido, 1998, Lawrence, 1998, Lindsley and Zimm, 1992, Palka, 1993, Bender et al., 1985, Kuhn et al., 1984, Bender et al., 1983, Duncan and Celniker, 2004, Davis et al., 2007, Phinchongsakuldit et al., 2004, Wong and Merritt, 2002) Uab (Akbari et al., 2006) Ubx (LaBeau et al., 2009, Chen and Rasmuson-Lestander, 2009, Pearson et al., 2005, Schwartz and Pirrotta, 2007, Xing and Lee, 2006, Negre and Ruiz, 2007, Richter et al., 2011, Duncan and Celniker, 2004, Ronshaugen and Levine, 2004, Burnette, 2005, Lewis et al., 1999, Qi et al., 2006, Pease and Bender, 2007, Crickmore and Mann, 2007, Liu et al., 2007, Shroff and Orenic, 2007, Bondos et al., 2007, Petruk et al., 2007, Kumar and Anderson, 2007, Maeda and Karch, 2006, Mihaly et al., 2006, Abrams et al., 2006, Petruk et al., 2006, Petruk et al., 2006, Schuettengruber, 2006, Pallavi et al., 2006, Stultz et al., 2006, Scuderi et al., 2006, Sanchez-Elsner et al., 2006, Sanchez-Elsner et al., 2006, Wang et al., 2006, Papp and Muller, 2006, Crickmore and Mann, 2006, Crickmore and Mann, 2006, Gilfillan et al., 2006, Klymenko et al., 2006, Culi et al., 2006, Hartl et al., 2008, Gutierrez et al., 2004, Rogulja-Ortmann and Technau, 2007, Pavlopoulos and Akam, 2007, Prasanth and Spector, 2007, Ogishima and Tanaka, 2007, Sandmann et al., 2007, de Navas et al., 2006, Kahn et al., 2006, Monier et al., 2007, Scholtz, 2006, Kreiman, 2004, Apitz et al., 2005, Tripura et al., 2011, Aerts et al., 2007, Dixit et al., 2008, Galindo et al., 2007, Girard et al., 2006, Brown et al., 2005, Huang et al., 2002, Chang et al., 2007, Hueber et al., 2007, Bello et al., 2007, Crickmore and Mann, 2007, Muller and Kassis, 2006, Stern, 2006, Chopra and Mishra, 2006, Braendle and Flatt, 2006, Fitzgerald and Bender, 2001, Tour et al., 2008, Hartl et al., 2008, Karlsson et al., 2008, Rogulja-Ortmann and Technau, 2008, Savla et al., 2008, Garaulet and Sánchez-Herrero, 2008, Stark et al., 2007, Bejarano et al., 2005, Shroff et al., 2007, Mohd-Sarip et al., 2005, Choo et al., 2011, Akbari et al., 2007, Ringrose and Paro, 2007, Duboule, 2007, Chauvet et al., 2000, Choi et al., 2000, de Ayala Alonso et al., 2007, Nanda and Brand, 2000, Wang et al., 2006, Tie et al., 2007, Holohan et al., 2007, Taghli-Lamallem et al., 2008, Kwong et al., 2008, Kankel et al., 2007, Hartl et al., 2008, Nekrasov et al., 2007, Zhang et al., 2008, Desprat et al., 2008, Walsh and Carroll, 2007, de la Roche and Bienz, 2007, Sipos et al., 2007, Coiffier et al., 2008, Prince et al., 2008, Nusinow et al., 2008, Rogulja-Ortmann et al., 2008, Davis et al., 2007, Gebelein and Mann, 2007, Di Stefano et al., 2007, Beisel et al., 2007, Merabet et al., 2007, Phinchongsakuldit et al., 2004, Sato et al., 2008, Miguel-Aliaga et al., 2008, Hauenschild et al., 2008, Lanzuolo et al., 2007, Bender, 2008, Stark et al., 2008, Tyler et al., 2008, Juven-Gershon et al., 2008, Thomsen et al., 2010, Pindyurin et al., 2007, Parrish et al., 2007, González et al., 2008, Oktaba et al., 2008, Garaulet et al., 2008, McKay et al., 2009, Gause et al., 2008, Lloret-Llinares et al., 2008, Noyes et al., 2008, Benítez et al., 2009, Bantignies et al., 2011, Saller and Bienz, 2001, Greer et al., 2009, Zhimulev et al., 2003, Fang et al., 2009, Chopra et al., 2009, Chopra et al., 2009, Grimm et al., 2009, Makhijani et al., 2007, Liu et al., 2009, Grimm et al., 2007, Diop et al., 2008, Pérez-Lluch et al., 2008, Gambetta et al., 2009, Gambetta et al., 2009, Tie et al., 2009, Zeitlinger et al., 2007, Cleard et al., 2006, Schwartz et al., 2006, Hernandez et al., 2004, Sinclair et al., 2009, Ohno et al., 2008, Tsubota et al., 2008, Paré et al., 2009, Bischoff et al., 2009, Grad et al., 2004, Salvaing et al., 2008, Percival-Smith et al., 2005, Crickmore et al., 2009, Glazov et al., 2005, Siepel et al., 2005, Li et al., 2010, Karlsson et al., 2010, Hueber et al., 2010, Ou et al., 2009, Enriquez et al., 2010, Reed et al., 2010, Scheuermann et al., 2010, Aldaz et al., 2010, Bunt et al., 2010, Cunningham et al., 2010, Wang et al., 2010, Schwartz et al., 2010, Stark et al., 2007, Tomoyasu et al., 2009, Bhatia et al., 2010, Dellino et al., 2002, Wong and Merritt, 2002, Merritt and Whitington, 2002, Kwon et al., 2003, Ahn et al., 2010, Marco et al., 2009, Su et al., 2010, de Navas et al., 2011, Saadaoui et al., 2011, Miura et al., 2011, The modENCODE Consortium, 2010, The modENCODE Consortium, 2010, Smith et al., 2011, Basu and Atchison, 2010, Ahn et al., 2011, Margueron et al., 2009, Chopra et al., 2008, Uhl et al., 2010, Mace et al., 2010, Kazemian et al., 2010, Herz et al., 2010, Majithia et al., 2011) ubx (Kockel et al., 2001, Walkley and Malik, 1996, Eickbush et al., 1995, Wang et al., 2006, Gebelein and Mann, 2007, Xylourgidis et al., 2006, Yassin et al., 2010, Tchuraev and Galimzyanov, 2009, Liu et al., 2008) UBx (Simcox et al., 1991) UBX (Hersh and Wood, 2008, Hersh et al., 2007, Pathak et al., 2007, Pallavi and Shashidhara, 2005, Kozma et al., 2008) Ubx1b (Tan et al., 2002, Bondos et al., 2002)
Name Synonym	anterobithorax (Lindsley and Zimm, 1992, Davis et al., 2007) bithorax (Dietrich, 2003, Calleja et al., 2002, Williams and Nagy, 2001, Hodin, 2000, Desplan, 1999, Lindsley and Zimm, 1992, Duncan and Celniker, 2004, Kavi et al., 2006) bithorax complex (Maeda and Karch, 2006) bithoraxoid (Lindsley and Zimm, 1992, Duncan and Celniker, 2004) Contrabithorax (Lindsley and Zimm, 1992, Duncan and Celniker, 2004) Haltere mimic (Lindsley and Zimm, 1992, ) postbithorax (Lindsley and Zimm, 1992, Duncan and Celniker, 2004, Davis et al., 2007) Ultabithorax (Shroff et al., 2007) Ultraabdominal (Bender and Fitzgerald, 2002) Ultrabithorax (Negre and Ruiz, 2007, de Navas et al., 2006, Duncan and Celniker, 2004, Pease and Bender, 2007, Kumar and Anderson, 2007, Maeda and Karch, 2006, Petruk et al., 2006, Mohit et al., 2006, Lemons and McGinnis, 2006, Prasanth and Spector, 2007, de Navas et al., 2006, Monier et al., 2007, Scholtz, 2006, Huang et al., 2002, Chang et al., 2007, Bello et al., 2007, Crickmore and Mann, 2007, Muller and Kassis, 2006, Chopra and Mishra, 2006, Braendle and Flatt, 2006, Lai et al., 2008, Hersh and Wood, 2008, Bejarano et al., 2005, Akbari et al., 2007, Chauvet et al., 2000, Choi et al., 2000, Nanda and Brand, 2000, Taghli-Lamallem et al., 2008, Hersh et al., 2007, Kankel et al., 2007, Riede, 2004, Nekrasov et al., 2007, Mohan et al., 2007, Zhang et al., 2008, Walsh and Carroll, 2007, de la Roche and Bienz, 2007, Petruk et al., 2008, Rogulja-Ortmann et al., 2008, Davis et al., 2007, Gebelein and Mann, 2007, Di Stefano et al., 2007, Dimitri et al., 2003, Sato et al., 2008, Lanzuolo et al., 2007, Stark et al., 2008, Tyler et al., 2008, Xylourgidis et al., 2006, Juven-Gershon et al., 2008, Garaulet et al., 2008, Lloret-Llinares et al., 2008, Saller and Bienz, 2001, Greer et al., 2009, Fang et al., 2009, Chopra et al., 2009, LaBeau et al., 2009, Makhijani et al., 2007, Liu et al., 2009, Diop et al., 2008, Pérez-Lluch et al., 2008, Prince et al., 2008, Hernandez et al., 2004, Grimm et al., 2007, Sinclair et al., 2009, Paré et al., 2009, Bischoff et al., 2009, Wilkie et al., 2001, Percival-Smith et al., 2005, Crickmore et al., 2009, Glazov et al., 2005, Karlsson et al., 2010, Hueber et al., 2010, Reed et al., 2010, Scheuermann et al., 2010, Wang et al., 2010, Bhatia et al., 2010, Wong and Merritt, 2002, Merritt and Whitington, 2002, Kwon et al., 2003, Ahn et al., 2010, Smith et al., 2011, Majithia et al., 2011, Liu et al., 2008)
Secondary FlyBase IDs
	FBgn0024276
References ( 1409 )
Generate a list of	All references relating to this gene ( 1409 )
List References by type	Research paper  ( 825 ) Supplementary material  ( 16 ) Review  ( 286 ) Erratum  ( 1 ) Personal communication to FlyBase  ( 16 ) Abstract  ( 216 ) FlyBase analysis  ( 1 ) Book review  ( 5 ) Obituary  ( 3 ) Book  ( 4 ) Curated genome annotation  ( 2 ) Protein sequence record  ( 1 ) Stock list  ( 4 ) Computer file  ( 4 ) DNA/RNA sequence record  ( 1 ) Conference report  ( 10 ) Biography  ( 3 ) Letter  ( 8 ) Automatic genome annotation  ( 1 ) Thesis  ( 1 )
Recent research papers ( 36 )
	Ahn et al., 2011, Dev. Biol. 355(2): 336--348 Segment-specific regulation of the Drosophila AP-2 gene during leg and antennal development. [FBrf0213960] Bantignies et al., 2011, Cell 144(2): 214--226 Polycomb-Dependent Regulatory Contacts between Distant Hox Loci in Drosophila. [FBrf0212775] Choo et al., 2011, PLoS ONE 6(4): e14778 Genome-wide analysis of the binding of the hox protein ultrabithorax and the hox cofactor homothorax in Drosophila. [FBrf0213420] de Navas et al., 2011, Development 138(1): 107--116 Integration of RNA processing and expression level control modulates the function of the Drosophila Hox gene Ultrabithorax during adult development. [FBrf0212483] Hudry et al., 2011, BMC Biol. 9: 5 Visualization of protein interactions in living Drosophila embryos by the bimolecular fluorescence complementation assay. [FBrf0213066] Majithia et al., 2011, Biomacromolecules 12(10): 3629--3637 On the Design of Composite Protein-Quantum Dot Biomaterials via Self-Assembly. [FBrf0216324] Miura et al., 2011, Genome Biol. Evol. 3: 129--139 Evolutionary Changes of the Target Sites of Two MicroRNAs Encoded in the Hox Gene Cluster of Drosophila and Other Insect Species. [FBrf0213060] Quan et al., 2011, Nat. Biotechnol. 29(5): 449--452 Parallel on-chip gene synthesis and application to optimization of protein expression. [FBrf0213642] Richter et al., 2011, Nat. Cell Biol. 13(9): 1029--1039 The tumour suppressor L(3)mbt inhibits neuroepithelial proliferation and acts on insulator elements. [FBrf0215050] Saadaoui et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(6): 2276--2281 Selection of distinct Hox-Extradenticle interaction modes fine-tunes Hox protein activity. [FBrf0212994] Smith et al., 2011, J. Biol. Chem. 286(13): 11391--11400 Small ubiquitin-like modifier (SUMO) conjugation impedes transcriptional silencing by the polycomb group repressor Sex Comb on Midleg. [FBrf0214411] Starr et al., 2011, Dev. Biol. 359(2): 290--302 Molecular dissection of cis-regulatory modules at the Drosophila bithorax complex reveals critical transcription factor signature motifs. [FBrf0216527] Tchurikov et al., 2011, Nucleic Acids Res. 39(9): 3667--3685 Genome-wide profiling of forum domains in Drosophila melanogaster. [FBrf0213631] Tripura et al., 2011, Int. J. Dev. Biol. 55(6): 583--590 Regulation and activity of JNK signaling in the wing disc peripodial membrane during adult morphogenesis in Drosophila. [FBrf0216296] Ahn et al., 2010, Int. J. Dev. Biol. 54(8-9): 1251--1258 Drosophila castor is regulated negatively by the Ubx and abdA genes, but positively by the AbdB gene. [FBrf0211815] Aldaz et al., 2010, Proc. Natl. Acad. Sci. U.S.A. 107(32): 14217--14222 Live imaging of Drosophila imaginal disc development. [FBrf0211511] Basu and Atchison, 2010, J. Cell. Biochem. 110(1): 62--69 CtBP levels control intergenic transcripts, PHO/YY1 DNA binding, and PcG recruitment to DNA. [FBrf0210665] Bhatia et al., 2010, Genes Cells 15(7): 725--735 Chromatin remodeling protein INO80 has a role in regulation of homeotic gene expression in Drosophila. [FBrf0211277] Bunt et al., 2010, Dev. Cell 19(2): 296--306 Hemocyte-Secreted Type IV Collagen Enhances BMP Signaling to Guide Renal Tubule Morphogenesis in Drosophila. [FBrf0211514] Cunningham et al., 2010, Mol. Cell. Biol. 30(3): 820--828 Characterization of the polycomb group response elements of the Drosophila melanogaster invected Locus. [FBrf0209731] Duncan et al., 2010, Dev. Biol. 347(1): 82--91 Control of the spineless antennal enhancer: Direct repression of antennal target genes by Antennapedia. [FBrf0211931] Enriquez et al., 2010, Development 137(3): 457--466 Multi-step control of muscle diversity by Hox proteins in the Drosophila embryo. [FBrf0209729] Herz et al., 2010, Mol. Cell. Biol. 30(10): 2485--2497 The H3K27me3 demethylase dUTX is a suppressor of notch- and Rb-dependent tumors in Drosophila. [FBrf0210661] Hueber et al., 2010, PLoS ONE 5(5): e10820 Improving Hox protein classification across the major model organisms. [FBrf0210952] Karlsson et al., 2010, PLoS Biol. 8(5): e1000368 Segment-specific neuronal subtype specification by the integration of anteroposterior and temporal cues. [FBrf0210822] Kazemian et al., 2010, PLoS Biol. 8(8): Quantitative analysis of the Drosophila segmentation regulatory network using pattern generating potentials. [FBrf0211688] Li et al., 2010, Genes Dev. 24(9): 933--946 Polycomb group genes Psc and Su(z)2 restrict follicle stem cell self-renewal and extrusion by controlling canonical and noncanonical Wnt signaling. [FBrf0210675] Mace et al., 2010, Bioinformatics 26(6): 761--769 Extraction and comparison of gene expression patterns from 2D RNA in situ hybridization images. [FBrf0210155] Reed et al., 2010, Genetics 184(3): 745--758 Alternative splicing modulates Ubx protein function in Drosophila melanogaster. [FBrf0210406] Scheuermann et al., 2010, Nature 465(7295): 243--247 Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB. [FBrf0210760] Schwartz et al., 2010, PLoS Genet. 6(1): e1000805 Alternative epigenetic chromatin states of polycomb target genes. [FBrf0209708] Su et al., 2010, PLoS Comput. Biol. 6(12): e1001020 Assessing Computational Methods of Cis-Regulatory Module Prediction. [FBrf0212482] Thomsen et al., 2010, Development 137(17): 2951--2960 Developmental RNA processing of 3'UTRs in Hox mRNAs as a context-dependent mechanism modulating visibility to microRNAs. [FBrf0211493] Uhl et al., 2010, Dev. Biol. 343(1-2): 154--166 Comparing anterior and posterior Hox complex formation reveals guidelines for predicting cis-regulatory elements. [FBrf0214949] Wang et al., 2010, Mol. Cell. Biol. 30(11): 2584--2593 Comparative analysis of chromatin binding by Sex Comb on Midleg (SCM) and other polycomb group repressors at a drosophila Hox gene. [FBrf0210763] Yassin et al., 2010, Evol. Dev. 12(3): 288--295 Catching the phylogenic history through the ontogenic hourglass: a phylogenomic analysis of Drosophila body segmentation genes. [FBrf0211054] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...