General Information
Symbol
Dmel\v
Species
D. melanogaster
Name
vermilion
Annotation Symbol
CG2155
Feature Type
FlyBase ID
FBgn0003965
Gene Model Status
Stock Availability
Enzyme Name (EC)
Tryptophan 2,3-dioxygenase (1.13.11.11)
Gene Snapshot
In progress.Contributions welcome.
Also Known As
TDO
Genomic Location
Cytogenetic map
Sequence location
X:10,923,972..10,925,631 [+]
Recombination map
1-33
Sequence
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
GO Summary Ribbons
Families, Domains and Molecular Function
Protein Family (UniProt, Sequence Similarities)
Belongs to the tryptophan 2,3-dioxygenase family. (P20351)
Molecular Function (see GO section for details)
Catalytic Activity (EC)
Experimental Evidence
L-tryptophan + O(2) = N-formyl-L-kynurenine (1.13.11.11)
Predictions / Assertions
L-tryptophan + O(2) = N-formyl-L-kynurenine (1.13.11.11)
Summaries
Gene Group Membership
OXIDOREDUCTASES ACTING ON SINGLE DONORS WITH INCORPORATION OF TWO ATOMS OF OXYGEN -
Oxidoreductases acting on single donors with incorporation of two atoms of oxygen, include dehydrogenases that oxidize single hydrogen or electron donors with the reduction of two oxygen atoms.
UniProt Contributed Function Data
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety (PubMed:23333332). Required during larval growth to control the level of potentially harmful free tryptophan in the hemolymph. In the adult the same reaction is the first step in the ommochrome biosynthetic pathway (PubMed:2108317).
(UniProt, P20351)
Phenotypic Description from the Red Book (Lindsley and Zimm 1992)
v: vermilion
The v+ gene, expressed in the eyes, fat body, and Malpighian tubules of the wild type (Nissani, 1975, Genet. Res. 26: 63-72), is believed to code for the enzyme tryptophane oxidase (also known as tryptophane pyrrolase)(EC 1.3.11.11), a 150,000 dalton protein that catalyzes the conversion of tryptophane into N-formylkynurenine. The eye color of v mutants is bright scarlet owing to absence of brown ommochrome; ocelli are colorless. Flies with the mutant combination y;w have white eyes. The eye color is wild type in genetically v eyes of gynandromorphs mosaic for wild type and v tissue (Sturtevant, 1932), indicating the non-autonomous nature of the vermilion gene. v eye disks develop wild-type pigmentation when transplanted into wild-type larvae (Beadle and Ephrussi, 1936). yw nuclei from preblastoderm stages implanted into the posterior end of a fertilized v;bw egg can produce a mosaic fly with brown eyes (Zalokar, 1973, Dev. Biol. 32: 189-93). The diffusuble v+ hormone of Beadle and Ephrussi involved in mosaic and transplantation experiments has been identified as kynurenine (Butenandt, Weidel, and Becker, 1940, Naturwissenschaften 28: 63-64). Activity of the inducible enzyme tryptophane oxidase is absent in v mutants (Baglioni, 1959, 1960). As a result, nonprotein tryptophane is accumulated in vermilion flies (Green, 1959) rather than converted into N-formylkynurenine and then into formic acid and kynurenine. In mutant larvae tryptophane in the fat body is not converted into kynurenine (Rizki, 1963; Rizki and Rizki, 1968). Certain v alleles (v1, v2, and vk) are suppressed by mutations at the su(s) locus; these mutants show wild-type eye color, fail to accumulate nonprotein tryptophane, and partially restore tryptophane oxidase activity in spite of the mutation at v (Schultz and Bridges, 1932; Green, 1952; Baglioni, 1960; Shapard, 1960; Kaufman, 1962; Marzluf, 1965; Tartof, 1969; Jacobson et al., 1982); other v alleles (v36f, v48a, v51a, v51b, v51c, and vE1) show no change in the mutant eye color with these su(s) alleles and little or no increase in tryptophane oxidase activity (small increase observed in su(s) v36f flies). Some brown pigment is formed under conditions of partial starvation in suppressed v mutants (Tatum and Beadle, 1938; Shapard, 1960), but starvation has no effect on unsuppressed v alleles.
Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the GBrowse view of Dmel\v or the JBrowse view of Dmel\v for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model
Gene model reviewed during 5.45
Sequence Ontology: Class of Gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
FBtr0073386
1305
379
Additional Transcript Data and Comments
Reported size (kB)
1.4 (northern blot)
1.4 (unknown)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
FBpp0073242
44.4
379
5.72
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Subunit Structure (UniProtKB)
Homotetramer. Dimer of dimers.
(UniProt, P20351)
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Nucleotide / Polypeptide Records
 
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\v using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Gene Ontology (11 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
inferred from direct assay
(assigned by UniProt )
inferred from direct assay
(assigned by UniProt )
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
inferred from biological aspect of ancestor with PANTHER:PTN000015587
(assigned by GO_Central )
inferred from sequence or structural similarity with UniProtKB:Q17P71
(assigned by UniProt )
inferred from electronic annotation with InterPro:IPR037217
(assigned by InterPro )
traceable author statement
inferred from biological aspect of ancestor with PANTHER:PTN000015587
(assigned by GO_Central )
inferred from sequence or structural similarity with UniProtKB:Q17P71
(assigned by UniProt )
Biological Process (8 terms)
Terms Based on Experimental Evidence (5 terms)
CV Term
Evidence
References
inferred from mutant phenotype
inferred from mutant phenotype
inferred from direct assay
(assigned by UniProt )
inferred from direct assay
(assigned by UniProt )
Terms Based on Predictions or Assertions (4 terms)
CV Term
Evidence
References
inferred from biological aspect of ancestor with PANTHER:PTN000015587
(assigned by GO_Central )
inferred from sequence or structural similarity with UniProtKB:Q17P71
(assigned by UniProt )
Cellular Component (0 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Expression Data
Transcript Expression
No Assay Recorded
Stage
Tissue/Position (including subcellular localization)
Reference
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
northern blot
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
The 1.4kb v transcript is first detected in 12-24hr embryos. Levels remain relatively constant throughout larval development, although a higher level is observed in early third instar than in late third instar larvae. A dramatic decline is seen in the pupal stage and relatively high levels are again detected in 2 to 3 day old adults.
v+37 transcripts are expressed in adults at a level sufficient to give a wild type phenotype. They are expressed at a level comparabe to that of vk transcripts in a su(s)6 vk genotype which is about 24% of the wild type v transcript level. In a su(s)38 or su(s)35 background the levels of v+37 transcripts are raised to 59% and 50% of wild type, respectively.
v transcripts are expressed at about 5% of the level of wild type in the v1 mutant.
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\v in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 1-3
  • Stages(s) 13-16
Alleles, Insertions, Transgenic Constructs and Phenotypes
Classical and Insertion Alleles ( 763 )
For All Classical and Insertion Alleles Show
 
Allele of v
Class
Mutagen
Associated Insertion
Stocks
Known lesion
    0
    --
      0
      --
        0
        --
          0
          --
            0
            --
              0
              --
                0
                --
                  0
                  --
                    0
                    --
                      0
                      --
                        0
                        --
                        0
                        --
                          0
                          Yes
                            0
                            --
                              0
                              --
                              Other relevant insertions
                              Transgenic Constructs ( 23 )
                              For All Alleles Carried on Transgenic Constructs Show
                              Transgenic constructs containing/affecting coding region of v
                              Allele of v
                              Mutagen
                              Associated Transgenic Construct
                              Stocks
                              Transgenic constructs containing regulatory region of v
                              reporter construct
                              Deletions and Duplications ( 138 )
                              Disrupted in
                              Summary of Phenotypes
                              For more details about a specific phenotype click on the relevant allele symbol.
                              Lethality
                              Allele
                              Sterility
                              Allele
                              Other Phenotypes
                              Allele
                              Phenotype manifest in
                              Allele
                              Orthologs
                              Human Orthologs (via DIOPT v7.1)
                              Homo sapiens (Human) (1)
                              Species\Gene Symbol
                              Score
                              Best Score
                              Best Reverse Score
                              Alignment
                              Complementation?
                              Transgene?
                              15 of 15
                              Yes
                              Yes
                              Model Organism Orthologs (via DIOPT v7.1)
                              Mus musculus (laboratory mouse) (1)
                              Species\Gene Symbol
                              Score
                              Best Score
                              Best Reverse Score
                              Alignment
                              Complementation?
                              Transgene?
                              14 of 15
                              Yes
                              Yes
                              Rattus norvegicus (Norway rat) (1)
                              13 of 13
                              Yes
                              Yes
                              Xenopus tropicalis (Western clawed frog) (1)
                              12 of 12
                              Yes
                              Yes
                              Danio rerio (Zebrafish) (2)
                              14 of 15
                              Yes
                              Yes
                              14 of 15
                              Yes
                              Yes
                              Caenorhabditis elegans (Nematode, roundworm) (1)
                              13 of 15
                              Yes
                              Yes
                              Arabidopsis thaliana (thale-cress) (0)
                              No orthologs reported.
                              Saccharomyces cerevisiae (Brewer's yeast) (0)
                              No orthologs reported.
                              Schizosaccharomyces pombe (Fission yeast) (0)
                              No orthologs reported.
                              Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG09190ANX )
                              Organism
                              Common Name
                              Gene
                              AAA Syntenic Ortholog
                              Multiple Dmel Genes in this Orthologous Group
                              Drosophila melanogaster
                              fruit fly
                              Drosophila suzukii
                              Spotted wing Drosophila
                              Drosophila simulans
                              Drosophila sechellia
                              Drosophila erecta
                              Drosophila yakuba
                              Drosophila ananassae
                              Drosophila pseudoobscura pseudoobscura
                              Drosophila persimilis
                              Drosophila willistoni
                              Drosophila virilis
                              Drosophila mojavensis
                              Drosophila grimshawi
                              Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091507MG )
                              Organism
                              Common Name
                              Gene
                              Multiple Dmel Genes in this Orthologous Group
                              Musca domestica
                              House fly
                              Glossina morsitans
                              Tsetse fly
                              Lucilia cuprina
                              Australian sheep blowfly
                              Mayetiola destructor
                              Hessian fly
                              Mayetiola destructor
                              Hessian fly
                              Mayetiola destructor
                              Hessian fly
                              Aedes aegypti
                              Yellow fever mosquito
                              Anopheles darlingi
                              American malaria mosquito
                              Anopheles gambiae
                              Malaria mosquito
                              Culex quinquefasciatus
                              Southern house mosquito
                              Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W05CM )
                              Organism
                              Common Name
                              Gene
                              Multiple Dmel Genes in this Orthologous Group
                              Bombyx mori
                              Silkmoth
                              Danaus plexippus
                              Monarch butterfly
                              Heliconius melpomene
                              Postman butterfly
                              Heliconius melpomene
                              Postman butterfly
                              Apis florea
                              Little honeybee
                              Apis mellifera
                              Western honey bee
                              Bombus impatiens
                              Common eastern bumble bee
                              Bombus terrestris
                              Buff-tailed bumblebee
                              Linepithema humile
                              Argentine ant
                              Megachile rotundata
                              Alfalfa leafcutting bee
                              Nasonia vitripennis
                              Parasitic wasp
                              Dendroctonus ponderosae
                              Mountain pine beetle
                              Dendroctonus ponderosae
                              Mountain pine beetle
                              Dendroctonus ponderosae
                              Mountain pine beetle
                              Dendroctonus ponderosae
                              Mountain pine beetle
                              Tribolium castaneum
                              Red flour beetle
                              Pediculus humanus
                              Human body louse
                              Rhodnius prolixus
                              Kissing bug
                              Cimex lectularius
                              Bed bug
                              Acyrthosiphon pisum
                              Pea aphid
                              Acyrthosiphon pisum
                              Pea aphid
                              Zootermopsis nevadensis
                              Nevada dampwood termite
                              Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X058W )
                              Organism
                              Common Name
                              Gene
                              Multiple Dmel Genes in this Orthologous Group
                              Ixodes scapularis
                              Black-legged tick
                              Ixodes scapularis
                              Black-legged tick
                              Ixodes scapularis
                              Black-legged tick
                              Stegodyphus mimosarum
                              African social velvet spider
                              Tetranychus urticae
                              Two-spotted spider mite
                              Daphnia pulex
                              Water flea
                              Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G080K )
                              Organism
                              Common Name
                              Gene
                              Multiple Dmel Genes in this Orthologous Group
                              Strongylocentrotus purpuratus
                              Purple sea urchin
                              Strongylocentrotus purpuratus
                              Purple sea urchin
                              Ciona intestinalis
                              Vase tunicate
                              Ciona intestinalis
                              Vase tunicate
                              Human Disease Model Data
                              FlyBase Human Disease Model Reports
                                Alleles Reported to Model Human Disease (Disease Ontology)
                                Download
                                Models ( 0 )
                                Allele
                                Disease
                                Evidence
                                References
                                Interactions ( 2 )
                                Allele
                                Disease
                                Interaction
                                References
                                Comments ( 0 )
                                 
                                Human Orthologs (via DIOPT v7.1)
                                Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
                                Homo sapiens (Human)
                                Gene name
                                Score
                                OMIM
                                OMIM Phenotype
                                Complementation?
                                Transgene?
                                Functional Complementation Data
                                Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
                                Interactions
                                Summary of Physical Interactions
                                esyN Network Diagram
                                Interactions Browser
                                Summary of Genetic Interactions
                                esyN Network Diagram
                                esyN Network Key:
                                Suppression
                                Enhancement

                                Please look at the allele data for full details of the genetic interactions
                                Starting gene(s)
                                Interaction type
                                Interacting gene(s)
                                Reference
                                Starting gene(s)
                                Interaction type
                                Interacting gene(s)
                                Reference
                                External Data
                                Subunit Structure (UniProtKB)
                                Homotetramer. Dimer of dimers.
                                (UniProt, P20351 )
                                Linkouts
                                BioGRID - A database of protein and genetic interactions.
                                DroID - A comprehensive database of gene and protein interactions.
                                InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
                                Pathways
                                Gene Group - Pathway Membership (FlyBase)
                                External Data
                                Linkouts
                                KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
                                Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                                Genomic Location and Detailed Mapping Data
                                Chromosome (arm)
                                X
                                Recombination map
                                1-33
                                Cytogenetic map
                                Sequence location
                                X:10,923,972..10,925,631 [+]
                                FlyBase Computed Cytological Location
                                Cytogenetic map
                                Evidence for location
                                9F11-9F11
                                Limits computationally determined from genome sequence between P{EP}sesBEP319&P{EP}ImpEP760 and P{EP}EP1321EP1321&P{EP}CG2061EP1537
                                Experimentally Determined Cytological Location
                                Cytogenetic map
                                Notes
                                References
                                Cytogenetic location of 10A1--10A2 based on known data for C901, v and sev, previous data described in FBrf0073632, and comparison with the physical map (Release 5.8).
                                10A1-10A2
                                (determined by in situ hybridisation)
                                10A-10A
                                (determined by in situ hybridisation)
                                Experimentally Determined Recombination Data
                                Notes
                                Stocks and Reagents
                                Stocks (15,130)
                                Genomic Clones (9)
                                 

                                Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

                                cDNA Clones (11)
                                 

                                Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

                                cDNA clones, fully sequences
                                BDGP DGC clones
                                Other clones
                                Drosophila Genomics Resource Center cDNA clones

                                For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

                                cDNA Clones, End Sequenced (ESTs)
                                BDGP DGC clones
                                RNAi and Array Information
                                Linkouts
                                DRSC - Results frm RNAi screens
                                GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                                Antibody Information
                                Laboratory Generated Antibodies
                                 
                                Commercially Available Antibodies
                                 
                                Other Information
                                Relationship to Other Genes
                                Source for database identify of
                                Source for identity of: v CG2155
                                Source for database merge of
                                Additional comments
                                Other Comments
                                Two regions, -300bp to -600bp and -60bp to-160bp, are important for maximal levels of expression in adults. Larval expression is fat body specific; expression depends on sequences between +19 and +36. This downstream element can be functionally replaced by a TATA box in vivo. When added to the wild type v promoter, a TATA element augments the level of v transcription by three to five fold.
                                The eye color of v1 mutants is bright scarlet owing to absence of brown ommochrome; ocelli are colorless. Flies with the mutant combination v1; bw1 have white eyes. Though v1, v2 and vk are suppressed by mutations at the su(s) locus (FBrf0002306; FBrf0008670; FBrf0013364; FBrf0013329; FBrf0014641; FBrf0017063; FBrf0020623; FBrf0064831), other v alleles (v36f, v48a, v51a, v51b, v51c and vE1) show no change in the mutant eye color with su(s) alleles and little or no increase in tryptophane oxidase activity (small increase observed in su(s) v36f flies). Starvation has no effect on eye color of unsuppressed v alleles.
                                Suppressor and reversion mutations exert an effect on pre-mRNA splicing.
                                Lesions in v block pigmentation in the eye, ocelli, tubule and fat body.
                                v pr mutants are able to synthesize xanthurenic acid 8-glucoside when fed with xanthuretic acid. The activity required for this synthesis via xanthuretic acid has been defined.
                                Certain v alleles (v1, v2 and vk) are suppressed by mutations at the su(s) locus; these mutants show wild-type eye color.
                                v alleles suppressed by mutation at the su(s) locus fail to accumulate nonprotein tryptophane and partially restore tryptophane oxidase activity in spite of the mutation at v.
                                v1 has been reverted by microinjection of wild-type DNA.
                                y1 w1 nuclei from preblastoderm stages implanted into the posterior end of a fertilized v1; bw1 egg can produce a mosaic fly with brown eyes.
                                Hereditary reversion of the eye color of v mutants to that of wild-type flies has been achieved by treatment of eggs with DNA.
                                In mutant larvae tryptophane in the fat body is not converted into kynurenine.
                                v alleles suppressed by mutation at the su(s) locus fail to accumulate nonprotein tryptophane and partially restore tryptophane oxidase activity in spite of the mutation at v. Tryptophane oxidase activity is absent in v1 mutants.
                                Certain v alleles (v1, v2 and vk) are suppressed by mutations at the su(s) locus; these mutants show wild-type eye color. Some brown pigment is formed under conditions of partial starvation in su(s) suppressed v mutants.
                                Tryptophane oxidase activity is absent in v1 mutants.
                                Nonprotein tryptophane is accumulated in v mutant flies rather than converted into N-formylkynurenine and then into formic acid and kynurenine.
                                The diffusible v+ involved in mosaic and transplantation experiments has been identified as kynurenine.
                                Some brown pigment is formed under conditions of partial starvation in su(s) suppressed v mutants.
                                Origin and Etymology
                                Discoverer
                                Morgan, Nov. 1910.
                                Etymology
                                Identification
                                External Crossreferences and Linkouts ( 455 )
                                Crossreferences
                                NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                                GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                                RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                                UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
                                UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
                                Other crossreferences
                                BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
                                InterPro - A database of protein families, domains and functional sites
                                KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
                                Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                                Linkouts
                                BioGRID - A database of protein and genetic interactions.
                                Drosophila Genomics Resource Center - Drosophila Genomics Resource Center cDNA clones
                                DPiM - Drosophila Protein interaction map
                                DroID - A comprehensive database of gene and protein interactions.
                                DRSC - Results frm RNAi screens
                                Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
                                FLIGHT - Cell culture data for RNAi and other high-throughput technologies
                                FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
                                FlyCyc - Genes from a BioCyc PGDB for Dmel
                                Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
                                Flygut - An atlas of the Drosophila adult midgut
                                FlyMine - An integrated database for Drosophila genomics
                                GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                                iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
                                InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
                                KEGG Genes - Molecular building blocks of life in the genomic space.
                                modMine - A data warehouse for the modENCODE project
                                Synonyms and Secondary IDs (14)
                                Reported As
                                Secondary FlyBase IDs
                                  Datasets (0)
                                  Study focus (0)
                                  Experimental Role
                                  Project
                                  Project Type
                                  Title
                                  References (359)