z2
Please see the JBrowse view of Dmel\zen2 for information on other features
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Gene model reviewed during 5.49
Gene model reviewed during 5.50
1.1 (northern blot)
0.9 (northern blot)
None of the polypeptides share 100% sequence identity.
252 (aa); 28 (kD)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\zen2 using the Feature Mapper tool.
Comment: reference states 3.5 hr AEL
Comment: anlage in statu nascendi
Comment: anlage in statu nascendi
zen2 transcripts are observed between 0 and 6 hrs of embryonic development with a peak at 2-4hrs on northern blots. No zen2 transcripts are observed in postembryonic stages. zen2 transcripts are observed along the dorsal surface of the pre-cellular blastoderm embryo by in situ hybridization. As gastrulation proceeds, they become restricted to the area of the dorsal folds.
Northern analysis of RNA from 0-24 hour embryos indicate that zen2 transcript is expressed in early embryos, and expression peaks at 2-3 hours of embryogenesis. Using radioactive in situ hybridization, zen2 expression is detected in the dorsal surface and the anterior and posterior poles of embryonic cycle 14 embryos. By gastrulation, zen2 expression is restricted to the dorsal surface. During germ band elongation, zen2 transcript is detected in the amnioserosa and a region of the dorsal ectoderm corresponding to the presumptive ptic lobe.
GBrowse - Visual display of RNA-Seq signals
View Dmel\zen2 in GBrowse 23-48
Map position inferred from close proximity to zen.
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Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: zen2 CG1048
A transient expression assay has been employed to investigate the potential of homeobox genes to function as transcriptional activators.
Molecular and genetic analysis of the pb locus has been performed.
Simultaneous deletion of both z2 and pb produces only a pb mutant phenotype. Thus absence of z2 function has no discernible effect on development or morphology.