βH, βH-spectrin, βHeavy-spectrin, βH-Spectrin, βH-Spec
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.45
13.0 | predicted (northern blot)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\kst using the Feature Mapper tool.
Immunolocalization was performed in a GMR > alpha- catenin::GFP background to provide a cytoskeletal marker, as phalloidin staining was incompatible with the fixation protocol used. Expression is reduced in 44-46 hours APF timepoint compared to earlier timepoints.
GBrowse - Visual display of RNA-Seq signalsView Dmel\kst in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
RNAi screen using dsRNA made from templates generated with primers directed against this gene causes a phenotype when assayed in Kc167 and S2R+ cells: binucleate cells.
kst is essential for normal epithelium morphogenesis of the follicle cell epithelium during oogenesis.
kst mutant individuals have a pleiotropic phenotype characterised by extensive larval lethality and, in adult escapers, rough eyes, bent wings, tracheal defects and infertility.