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Gene Dmel\snRNA:U2:84Cb

General Information
Symbol	Dmel\snRNA:U2:84Cb	Species	D. melanogaster
Name	small nuclear RNA U2 at 84Cb	Annotation symbol
Feature type	snRNA_gene	FlyBase ID	FBgn0004194
Gene Model Status	Unannotated	Stock availability	None publicly available
Also Known As	U2 snRNA, U2
Genomic Location
Chromosome (arm)		Recombination map	3-[47.5]
Cytogenetic map	84C-84C	Sequence location
Summary Information
Automatically generated summary See sections below for more information	The gene small nuclear RNA U2 at 84Cb is referred to in FlyBase by the symbol Dmel\snRNA:U2:84Cb (FBgn0004194). It is a snRNA_gene from Drosophila melanogaster. Its molecular function is unknown. It is reported to be involved in the biological process: mRNA splicing, via spliceosome. No alleles are reported. It has no annotated transcripts. Gene has not been localized to the genome sequence.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 84C-84C
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location	3-[47.5]
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa)
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Mapped Features
Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Cajal body inferred from direct assay (Liu et al., 2006)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
modENCODE Anatomy RNA-Seq
modENCODE Development RNA-Seq
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
Expression Clusters
External Data & Images
Linkouts
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of snRNA:U2:84Cb Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 0 )
For All Alleles Carried on Transgenic Constructs Show
Allele of snRNA:U2:84Cb Class Mutagen Stocks Known lesion
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
Cajal body inferred from direct assay (Liu et al., 2006)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
mRNA splicing, via spliceosome non-traceable author statement (FlyBase, 1992-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   snRNA_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions snRNA:U2:84Cb allele Gene References
External Data
Linkouts
Orthologs
OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search No orthologs identified Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (None identified)
No orthologies identified
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 0 )
Genomic Clones ( 0 )
cDNA Clones ( 0 )
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts	GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 5657001
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	There is no candidate U2 snRNA gene annotated in the 84C region of the release 3 genome. (FlyBase Genome Annotators, 2002-2003)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
Other Crossreferences
Linkouts
	GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 5657001
Synonyms & Secondary IDs ( 9 )
Reported As
Symbol Synonym	dU2 (Liu et al., 2006) snRNA:U2   snRNA:U2:84Cb   U2 (Liu et al., 2006, Kroiss et al., 2008, Gonsalvez et al., 2008) U2snRNA   U2 snRNA (Komonyi et al., 2005, Liu et al., 2009, Deryusheva and Gall, 2009, Labourier and Rio, 2001, Rajendra et al., 2007) U2snRNA84Cb
Name Synonym	small nuclear RNA U2   small nuclear RNA U2 at 84Cb   U2 snRNA (Liu et al., 2006)
Secondary FlyBase IDs
	FBgn0003919 FBgn0003924
References ( 11 )
Research paper	Deryusheva and Gall, 2009, Mol. Biol. Cell 20(24): 5250--5259 Small Cajal Body-specific RNAs of Drosophila Function in the Absence of Cajal Bodies. [FBrf0209497] Liu et al., 2009, Mol. Biol. Cell 20(6): 1661--1670 Coilin is essential for Cajal body organization in Drosophila melanogaster. [FBrf0207514] Gonsalvez et al., 2008, RNA 14(5): 878--887 Sm protein methylation is dispensable for snRNP assembly in Drosophila melanogaster. [FBrf0205403] Kroiss et al., 2008, Proc. Natl. Acad. Sci. U.S.A. 105(29): 10045--10050 Evolution of an RNP assembly system: a minimal SMN complex facilitates formation of UsnRNPs in Drosophila melanogaster. [FBrf0205768] Rajendra et al., 2007, J. Cell Biol. 176(6): 831--841 A Drosophila melanogaster model of spinal muscular atrophy reveals a function for SMN in striated muscle. [FBrf0194681] Liu et al., 2006, J. Cell Biol. 172(6): 875--884 The Drosophila melanogaster Cajal body. [FBrf0190937] Komonyi et al., 2005, J. Biol. Chem. 280(13): 12397--12404 DTL, the Drosophila Homolog of PIMT/Tgs1 Nuclear Receptor Coactivator-interacting Protein/RNA Methyltransferase, Has an Essential Role in Development. [FBrf0184045] Labourier and Rio, 2001, RNA 7(3): 457--470 Purification of Drosophila snRNPs and characterization of two populations of functional U1 particles. [FBrf0135940] Alonso et al., 1984, Nucleic Acids Res. 12: 9543--9550 Divergence of U2 snRNA sequences in the genome of Drosophila melanogaster. [FBrf0041601]
FlyBase analysis	FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]