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General Information
Symbol
Dmel\nonA
Species
D. melanogaster
Name
no on or off transient A
Annotation Symbol
CG4211
Feature Type
FlyBase ID
FBgn0004227
Gene Model Status
Stock Availability
Gene Snapshot
In progress.Contributions welcome.
Also Known As

diss, no-on-transient A, Bj6, non-A, dissonance

Key Links
Genomic Location
Cytogenetic map
Sequence location
X:16,361,569..16,371,547 [+]
Recombination map

1-53

RefSeq locus
NC_004354 REGION:16361569..16371547
Sequence
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
Function
GO Summary Ribbons
Protein Family (UniProt)
-
Molecular Function (GO)
[Detailed GO annotations]
Summaries
Protein Function (UniProtKB)
Required for normal vision and courtship behavior in Drosophila.
(UniProt, Q04047)
Phenotypic Description (Red Book; Lindsley and Zimm 1992)
nonA: no on or off transient-A (J.C. Hall)
Defective optomotor responses and phototaxis, with the former being especially defective (Heisenberg, 1972; Heisenberg and Buchner, 1977; Kulkarni et al., 1988). Poor orientation behavior in Y-maze (Bulthoff, 1982a, b). nonA5 flies exhibit specific lack of responses to front-to-back moving visual stimuli, whereas reaction to back-to-front motion is intact (Heisenberg, 1972). Physiologically, there are reduced or absent light-on and light-off transient spikes in electroretinogram, whereas photoreceptor potential is normal (Hotta and Benzer, 1970; Pak et al., 1970; Heisenberg, 1971; Kulkarni et al., 1988; Jones and Rubin, 1990). Larval visual response (re negative phototaxis) normal [Hotta and Keng, 1984, Animal Behavior: Neurophysiological and Ethological Approaches (Aoki et al., eds.). Springer-Verlag, Berlin, pp. 49-60]. Courtship song is abnormal, as influenced by one, possibly two, mutant alleles; nonA9 (originally diss) males produce abnormal song, regarding pulses relatively late in trains of such song sounds (each one resulting from a bout of wing vibration); the abnormalities are polycyclicity (Kulkarni et al., 1988) and anomalous intra-pulse frequency components (Wheeler et al., 1989); pulses early in trains, or throughout short ones, are nearly normal; courtship hum sounds manifest irregular sine waves, though their fundamental frequencies are normal (Wheeler et al., 1989). nonA9 by itself is also an optomotor-defective/ERG-abnormal mutant (Kulkarni et al., 1988) and fails to complement other mutant alleles with regard to these visual phenotypes (Rendahl, Kulkarni, and Hall, unpublished); but these heterozygotes, in a homozygous tra genetic background, sing normally (with the possible exception of nonA2/nonA9, Rendahl et al., unpublished), as do males hemizygous for alleles isolated as visual mutants.
Gene Model and Products
Number of Transcripts
4
Number of Unique Polypeptides
3

Please see the GBrowse view of Dmel\nonA or the JBrowse view of Dmel\nonA for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.50

Sequence Ontology: Class of Gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
FBtr0074232
3747
700
FBtr0074233
2358
742
FBtr0100586
5008
698
FBtr0340313
6746
700
Additional Transcript Data and Comments
Reported size (kB)

4.0, 3.0, 2.8 (northern blot)

Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
FBpp0074011
77.0
700
9.97
FBpp0074012
82.0
742
9.67
FBpp0100043
77.0
698
9.80
FBpp0309274
77.0
700
9.97
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

700 aa isoforms: nonA-PA, nonA-PD
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments

The RNA-binding motif of nonA protein is most

similar to those of Sxl protein, the polyA-binding proteins, and tra2

protein.

The two nonA proteins differ only in the C-terminal 33 (or 35) amino acids. Transformation experiments show that the 700aa protein is required for the function of nonA in vision.

External Data
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\nonA using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Gene Ontology (12 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
traceable author statement
inferred from sequence or structural similarity
inferred from biological aspect of ancestor with PANTHER:PTN000573351
(assigned by GO_Central )
inferred from biological aspect of ancestor with PANTHER:PTN000573360
(assigned by GO_Central )
Biological Process (6 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
Terms Based on Predictions or Assertions (6 terms)
CV Term
Evidence
References
inferred by curator from GO:0071011,GO:0071013
inferred from biological aspect of ancestor with PANTHER:PTN000573351
(assigned by GO_Central )
non-traceable author statement
inferred from biological aspect of ancestor with PANTHER:PTN000573360
(assigned by GO_Central )
non-traceable author statement
Cellular Component (3 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
inferred from high throughput direct assay
inferred from high throughput direct assay
inferred from direct assay
inferred from high throughput direct assay
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
inferred from biological aspect of ancestor with PANTHER:PTN000573351
(assigned by GO_Central )
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
No Assay Recorded
Stage
Tissue/Position (including subcellular localization)
Reference
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
western blot
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data

During oogenesis, observed in nuclei of follicle cell, nurse cells, and the oocyte. In embryos, observed in nuclei of cells at cellular blastoderm; expressed throughout embryonic development. In larval salivary glands, localized to polytene chromosomes.

@FBgn0004227:nonA @ is nuclear except in early embryos prior to cellular blastoderm stage where it is cytoplasmic.

Marker for
 
Subcellular Localization
CV Term
Evidence
References
inferred from high throughput direct assay
inferred from high throughput direct assay
inferred from direct assay
inferred from high throughput direct assay
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\nonA in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 18 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 29 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of nonA
Transgenic constructs containing regulatory region of nonA
Deletions and Duplications ( 35 )
Phenotypes
Orthologs
Human Orthologs (via DIOPT v7.1)
Homo sapiens (Human) (16)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
11 of 15
Yes
Yes
10 of 15
No
Yes
10 of 15
No
Yes
 
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
 
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
 
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
 
1 of 15
No
No
 
1 of 15
No
No
 
Model Organism Orthologs (via DIOPT v7.1)
Mus musculus (laboratory mouse) (15)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
12 of 15
Yes
Yes
10 of 15
No
Yes
10 of 15
No
Yes
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
Rattus norvegicus (Norway rat) (15)
9 of 13
Yes
Yes
9 of 13
Yes
Yes
3 of 13
No
Yes
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
Xenopus tropicalis (Western clawed frog) (6)
6 of 12
Yes
Yes
5 of 12
No
Yes
1 of 12
No
No
1 of 12
No
No
1 of 12
No
No
1 of 12
No
No
Danio rerio (Zebrafish) (19)
11 of 15
Yes
Yes
10 of 15
No
Yes
10 of 15
No
Yes
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (11)
11 of 15
Yes
Yes
1 of 15
No
No
1 of 15
No
Yes
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
Arabidopsis thaliana (thale-cress) (16)
2 of 9
Yes
Yes
2 of 9
Yes
No
1 of 9
No
Yes
1 of 9
No
No
1 of 9
No
No
1 of 9
No
No
1 of 9
No
No
1 of 9
No
No
1 of 9
No
No
1 of 9
No
No
1 of 9
No
No
1 of 9
No
No
1 of 9
No
No
1 of 9
No
No
1 of 9
No
No
1 of 9
No
No
Saccharomyces cerevisiae (Brewer's yeast) (4)
1 of 15
Yes
No
1 of 15
Yes
No
1 of 15
Yes
No
1 of 15
Yes
Yes
Schizosaccharomyces pombe (Fission yeast) (4)
2 of 12
Yes
Yes
1 of 12
No
No
1 of 12
No
Yes
1 of 12
No
No
Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG091908Z7 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila melanogaster
fruit fly
Drosophila suzukii
Spotted wing Drosophila
Drosophila suzukii
Spotted wing Drosophila
Drosophila simulans
Drosophila sechellia
Drosophila erecta
Drosophila yakuba
Drosophila ananassae
Drosophila pseudoobscura pseudoobscura
Drosophila pseudoobscura pseudoobscura
Drosophila pseudoobscura pseudoobscura
Drosophila persimilis
Drosophila willistoni
Drosophila virilis
Drosophila mojavensis
Drosophila grimshawi
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915054H )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Glossina morsitans
Tsetse fly
Lucilia cuprina
Australian sheep blowfly
Mayetiola destructor
Hessian fly
Aedes aegypti
Yellow fever mosquito
Anopheles darlingi
American malaria mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Culex quinquefasciatus
Southern house mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W04ZE )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Danaus plexippus
Monarch butterfly
Heliconius melpomene
Postman butterfly
Apis florea
Little honeybee
Apis mellifera
Western honey bee
Bombus impatiens
Common eastern bumble bee
Bombus impatiens
Common eastern bumble bee
Bombus terrestris
Buff-tailed bumblebee
Bombus terrestris
Buff-tailed bumblebee
Linepithema humile
Argentine ant
Megachile rotundata
Alfalfa leafcutting bee
Nasonia vitripennis
Parasitic wasp
Dendroctonus ponderosae
Mountain pine beetle
Dendroctonus ponderosae
Mountain pine beetle
Tribolium castaneum
Red flour beetle
Tribolium castaneum
Red flour beetle
Pediculus humanus
Human body louse
Rhodnius prolixus
Kissing bug
Cimex lectularius
Bed bug
Acyrthosiphon pisum
Pea aphid
Zootermopsis nevadensis
Nevada dampwood termite
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X09YH )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Ixodes scapularis
Black-legged tick
Ixodes scapularis
Black-legged tick
Stegodyphus mimosarum
African social velvet spider
Tetranychus urticae
Two-spotted spider mite
Daphnia pulex
Water flea
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G09T7 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Ciona intestinalis
Vase tunicate
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Paralogs
Paralogs (via DIOPT v7.1)
Drosophila melanogaster (Fruit fly) (12)
8 of 10
2 of 10
2 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 1 )
    Modifiers Based on Experimental Evidence ( 1 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    esyN Network Diagram
    Show neighbor-neighbor interactions:
    Select Layout:
    Legend:
    Protein
    RNA
    Selected Interactor(s)
    Interactions Browser

    Please see the Physical Interaction reports below for full details
    RNA-protein
    Physical Interaction
    Assay
    References
    protein-protein
    Physical Interaction
    Assay
    References
    Summary of Genetic Interactions
    esyN Network Diagram
    esyN Network Key:
    Suppression
    Enhancement

    Please look at the allele data for full details of the genetic interactions
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    External Data
    Linkouts
    BioGRID - A database of protein and genetic interactions.
    DroID - A comprehensive database of gene and protein interactions.
    InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Pathways
    Signaling Pathways (FlyBase)
    Metabolic Pathways
    External Data
    Linkouts
    Genomic Location and Detailed Mapping Data
    Chromosome (arm)
    X
    Recombination map

    1-53

    Cytogenetic map
    Sequence location
    X:16,361,569..16,371,547 [+]
    FlyBase Computed Cytological Location
    Cytogenetic map
    Evidence for location
    14B18-14C1
    Limits computationally determined from genome sequence between P{EP}Cyp1EP1073&P{EP}Dsp1EP355 and P{EP}EP1493EP1493
    Experimentally Determined Cytological Location
    Cytogenetic map
    Notes
    References
    14B-14C
    (determined by in situ hybridisation)
    14C1-14C2
    (determined by in situ hybridisation)
    Experimentally Determined Recombination Data
    Left of (cM)
    Right of (cM)
    Notes
    Stocks and Reagents
    Stocks (14)
    Genomic Clones (20)
    cDNA Clones (126)
     

    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

    cDNA clones, fully sequences
    BDGP DGC clones
    Other clones
    Drosophila Genomics Resource Center cDNA clones

    For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

    cDNA Clones, End Sequenced (ESTs)
    RNAi and Array Information
    Linkouts
    DRSC - Results frm RNAi screens
    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
    Antibody Information
    Laboratory Generated Antibodies
    Commercially Available Antibodies
     
    Other Information
    Relationship to Other Genes
    Source for database identify of
    Source for database merge of
    Additional comments
    Other Comments

    Dissection of the functional domains of nonA.

    "Gene order: In direction of increasing cytology: Cyp1- nonA?" was stated as revision.

    The RRM motifs of nonA have been analysed by in vitro mutagenesis. RRM1 mutants cause optomotor blindness and an absence of transient spikes in the ERG. RRM2 mutants cause mildly mutant song pulses and trains.

    Spatial distribution of nonA protein was followed by confocal laser scanning microscopy in the nuclei of living cells throughout embryogenesis. Active uptake of nonA protein from cytoplasm to nucleus was observed from nuclear cycle 14 onwards. Significant differences between the distribution in fixed and living embryos were noted. The nonA protein was localized in the nuclei of living embryos at discrete sites, mostly at the periphery and sometimes tightly clustered. Observations suggest that specific protein complexes are mobile and associate with active interphase chromatin.

    A sequence comparison and numerical analysis of the RRM-containing (RNA recognition motif) proteins suggests that functionally related RRM-containing proteins have significant sequence similarities in their RRMs.

    Germline clonal analysis demonstrates that nonA has an essential function in the female germline.

    Murine NonO is homologous to nonA, essential for visual processing.

    Mutants exhibit defective courtship song.

    Expression patterns and nonA protein structure have been determined.

    nonA locus has been molecularly cloned, mRNA transcripts characterized and nonA mutant phenotypes rescued by P element mediated transformation.

    nonA binds to the chromosome within 2.5kb 5' of the start of Sgs4 transcription.

    nonA has been cloned and sequenced and its expression pattern has been analysed.

    Aberrant intervals between song pulses were observed in nonA mutant and cac, nonA double mutant songs. Males displayed a defect in song hums manifested by an irregular sine wave, although the fundamental frequencies were normal.

    Mosaic analysis (Hotta and Benzer, 1970) suggested that ERG defects map to photoreceptors; but too few gynandromorphs were analyzed to rule out an optic-lobe 'focus', which is more likely to be the focus for visual-movement-response abnormalities (especially those reported by Heisenberg, 1972). Two genomic clones, whose distal endpoints are just distal to nonA-rescuing DNA fragments, rescue each of two non-allelic lethals <up>l(1)14Cc and l(1)14Ca</up> that map to the same cytogenetic interval as does nonA; transformation with overlapping genomic clones indicates an order from left to right of l(1)14Cc l(1)14Ca nonA (Jones and Rubin, 1990). Both lethals complement the ERG defects of nonA5 (Jones and Rubin, 1990) and complement the song abnormality of nonA9 (Kulkarni and Hall, unpublished).

    Defective optomotor responses and phototaxis, with the former being especially defective (Heisenberg, 1972; Heisenberg and Buchner, 1977; Kulkarni, Steinlauf and Hall, 1988). Poor orientation behavior in Y-maze (Bulthoff, 1982). nonA5 flies exhibit specific lack of responses to front-to-back moving visual stimuli, whereas reaction to back-to-front motion is intact (Heisenberg, 1972). Physiologically, there are reduced or absent light-on and light-off transient spikes in electroretinogram, whereas photoreceptor potential is normal (Hotta and Benzer, 1970; Pak, Grossfield and Arnold, 1970; Heisenberg, 1971; Kulkarni, Steinlauf and Hall, 1988; Jones and Rubin, 1990). Larval visual response (re negative phototaxis) normal (Hotta and Keng, 1984). Courtship song is abnormal, as influenced by one, possibly two, mutant alleles; nonA9 (originally diss) males produce abnormal song, regarding pulses relatively late in trains of such song sounds (each one resulting from a bout of wing vibration); the abnormalities are polycyclicity (Kulkarni, Steinlauf and Hall, 1988) and anomalous intra-pulse frequency components (Wheeler et al., 1989); pulses early in trains, or throughout short ones, are nearly normal; courtship hum sounds manifest irregular sine waves, though their fundamental frequencies are normal (Wheeler et al., 1989). nonA9 by itself is also an optomotor-defective/ERG-abnormal mutant (Kulkarni et al., 1988) and fails to complement other mutant alleles with regard to these visual phenotypes (Rendahl, Jones, Kulkarni, Bagully and Hall, 1992); but these heterozygotes, in a homozygous tra genetic background, sing normally (with the possible exception of nonA2/nonA9, Rendahl et al., 1992), as do males hemizygous for alleles isolated as visual mutants.

    Origin and Etymology
    Discoverer
    Etymology
    Identification
    External Crossreferences and Linkouts ( 53 )
    Sequence Crossreferences
    NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
    GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
    GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
    RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
    UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
    UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
    Other crossreferences
    Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
    Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
    Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
    Flygut - An atlas of the Drosophila adult midgut
    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
    KEGG Genes - Molecular building blocks of life in the genomic space.
    modMine - A data warehouse for the modENCODE project
    Linkouts
    BioGRID - A database of protein and genetic interactions.
    DPiM - Drosophila Protein interaction map
    DroID - A comprehensive database of gene and protein interactions.
    DRSC - Results frm RNAi screens
    FLIGHT - Cell culture data for RNAi and other high-throughput technologies
    FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
    FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
    FlyMine - An integrated database for Drosophila genomics
    InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Synonyms and Secondary IDs (22)
    Reported As
    Symbol Synonym
    opm2
    x14
    Name Synonyms
    Bj6-monoclonal-antibody
    Positive spike II group
    no on or off transient A
    no on or off transient-A
    no-on-transient-A
    non-on-transient-A
    Secondary FlyBase IDs
    • FBgn0000188
    • FBgn0002957
    Datasets (0)
    Study focus (0)
    Experimental Role
    Project
    Project Type
    Title
    References (174)