FB2020_06, released Dec 22, 2020

Gene: Dmel\LysS

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General Information
Symbol
Dmel\LysS
Species
D. melanogaster
Name
Lysozyme S
Annotation Symbol
CG1165
Feature Type
protein_coding_gene
FlyBase ID
FBgn0004430
Gene Model Status
Current
Stock Availability
3 publicly available
Gene Snapshot
Contributions welcome
Other Summaries
Key Links
Genomic Location
Cytogenetic map
61F4-61F4
Sequence location
3L:1,227,747..1,228,238 [+]
Recombination map

3-0

RefSeq locus
NT_037436 REGION:1227747..1228238
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (3 terms)
Molecular Function (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
enables lysozyme activity
inferred from sequence or structural similarity with UniProtKB:P00697
(FlyBase Curators, 2008--)
inferred from sequence or structural similarity
(Daffre et al., 1994)
Biological Process (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
involved_in defense response to Gram-negative bacterium
inferred from sequence or structural similarity with UniProtKB:P00697
(FlyBase Curators, 2008--)
Cellular Component (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
located_in extracellular space
inferred from sequence or structural similarity with UniProtKB:C1BF55
(FlyBase Curators, 2008--)
Gene Group (FlyBase)
Protein Family (UniProt)
Belongs to the glycosyl hydrolase 22 family. (P37160)
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
LYSOZYMES -
Lysozymes belong to the glycoside hydrolase family 22. Lysozymes damage bacterial cell walls by hydrolyzing the β-(1,4)-glycosidic bond between N-acetyl-muraminic acid and N-acetyl-D-glucosamine of peptidoglycan, causing cell lysis. (Adapted from PMID:22581338, PMID:20413917, PMID:20049505).
Protein Function (UniProtKB)
Unlikely to play an active role in the humoral immune defense. May have a function in the digestion of bacteria in the food.
(UniProt, P37160)
Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\LysS for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.46

Gene model reviewed during 5.48

Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
LysS-RA
FBtr0072631
NM_057481
492
140
Additional Transcript Data and Comments
Reported size (kB)

0.482 (longest cDNA)

(Daffre et al., 1994)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
LysS-PA
FBpp0072527
15.7
140
4.45
NP_476829
AAF47453
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)

139 (aa)

(Daffre et al., 1994)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\LysS using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
RNase protection, primer extension, SI map
Stage
Tissue/Position (including subcellular localization)
Reference
larval stage
gastric caecum
(Daffre et al., 1994)
(Daffre et al., 1994)
Additional Descriptive Data

LysS transcripts are detected in larvae with the highest level at the third instar stage. They are detected mainly in the epithelium of the gastric caecae by in situ hybridization. The levels of LysS transcripts are drastically reduced after bacterial injection.

(Daffre et al., 1994)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\LysS in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 0 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of LysS
Transgenic constructs containing regulatory region of LysS
Deletions and Duplications ( 0 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
Phenotype manifest in
Allele
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (9)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\LYZ
11 of 15
Yes
No
10  
Hsap\LYZL1
7 of 15
No
No
Hsap\LYZL2
7 of 15
No
No
1  
Hsap\SPACA3
7 of 15
No
No
Hsap\LYZL4
6 of 15
No
No
Hsap\LYZL6
6 of 15
No
No
Hsap\SPACA5B
6 of 15
No
No
Hsap\LALBA
5 of 15
No
No
1  
Hsap\SPACA5
4 of 15
No
No
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (9)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Lyz1
11 of 15
Yes
No
Mmus\Lyz2
11 of 15
Yes
No
Mmus\9530003J23Rik
10 of 15
No
No
Mmus\Lyzl1
8 of 15
No
Yes
Mmus\Lyzl6
8 of 15
No
No
Mmus\Spaca3
8 of 15
No
No
Mmus\Spaca5
8 of 15
No
No
Mmus\Lalba
5 of 15
No
No
Mmus\Lyzl4
4 of 15
No
Yes
Rattus norvegicus (Norway rat) (9)
Rnor\Lyz2
11 of 13
Yes
Yes
Rnor\RGD1306474
10 of 13
No
Yes
Rnor\Lyc2
9 of 13
No
Yes
Rnor\Lyzl6
7 of 13
No
Yes
Rnor\Spaca3
7 of 13
No
No
Rnor\Lyzl1
6 of 13
No
No
Rnor\Spaca5
6 of 13
No
No
Rnor\Lalba
5 of 13
No
No
Rnor\Lyzl4
5 of 13
No
No
Xenopus tropicalis (Western clawed frog) (6)
Xtro\MGC89221
4 of 12
Yes
Yes
Xtro\LOC100493166
2 of 12
No
Yes
Xtro\LOC100493330
2 of 12
No
Yes
Xtro\LOC101730983
2 of 12
No
Yes
Xtro\lyz
2 of 12
No
Yes
Xtro\spaca5
2 of 12
No
Yes
Danio rerio (Zebrafish) (1)
Drer\lyz
5 of 15
Yes
No
Caenorhabditis elegans (Nematode, roundworm) (0)
No records found.
Arabidopsis thaliana (thale-cress) (0)
No records found.
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (0)
No records found.
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190I6N )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00004539
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00004540
Drosophila simulans
Dsim\GD26789
Drosophila simulans
Dsim\GD17617
Drosophila erecta
Dere\GG14763
Drosophila yakuba
Dyak\LysS
Drosophila ananassae
Dana\GF24437
Drosophila pseudoobscura pseudoobscura
Dpse\GA11118
Drosophila willistoni
Dwil\GK21117
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG09150DML )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17020217
Musca domestica
House fly
Mdoa\17011173
Musca domestica
House fly
Mdoa\17020222
Musca domestica
House fly
Mdoa\17019165
Musca domestica
House fly
Mdoa\17023801
Musca domestica
House fly
Mdoa\17023799
Musca domestica
House fly
Mdoa\17020216
Musca domestica
House fly
Mdoa\17011177
Musca domestica
House fly
Mdoa\17020219
Musca domestica
House fly
Mdoa\17006233
Musca domestica
House fly
Mdoa\17011175
Musca domestica
House fly
Mdoa\17020228
Musca domestica
House fly
Mdoa\17017786
Musca domestica
House fly
Mdoa\17019513
Musca domestica
House fly
Mdoa\17020225
Musca domestica
House fly
Mdoa\17020220
Musca domestica
House fly
Mdoa\17015481
Musca domestica
House fly
Mdoa\17011176
Musca domestica
House fly
Mdoa\17013391
Musca domestica
House fly
Mdoa\17011178
Musca domestica
House fly
Mdoa\17011174
Musca domestica
House fly
Mdoa\17020223
Musca domestica
House fly
Mdoa\17020227
Musca domestica
House fly
Mdoa\17015482
Musca domestica
House fly
Mdoa\17011180
Musca domestica
House fly
Mdoa\17021690
Musca domestica
House fly
Mdoa\17021630
Glossina morsitans
Tsetse fly
Gmor\GMOY000104
Glossina morsitans
Tsetse fly
Gmor\GMOY000103
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_08204
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_09595
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_09812
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_09833
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_08203
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_09596
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_06269
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_06270
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_13932
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_06268
Mayetiola destructor
Hessian fly
Mdes\Mdes004385
Aedes aegypti
Yellow fever mosquito
Aaeg\LYSC7A
Aedes aegypti
Yellow fever mosquito
Aaeg\LYSC11
Aedes aegypti
Yellow fever mosquito
Aaeg\LYSC10
Aedes aegypti
Yellow fever mosquito
Aaeg\LYSC9
Aedes aegypti
Yellow fever mosquito
Aaeg\LYSC7B
Aedes aegypti
Yellow fever mosquito
Aaeg\LYSC4
Anopheles darlingi
American malaria mosquito
Adar\ADAC005092
Anopheles darlingi
American malaria mosquito
Adar\ADAC005629
Anopheles darlingi
American malaria mosquito
Adar\ADAC005089
Anopheles gambiae
Malaria mosquito
Agam\LYSC1
Anopheles gambiae
Malaria mosquito
Agam\LYSC8
Anopheles gambiae
Malaria mosquito
Agam\LYSC3
Anopheles gambiae
Malaria mosquito
Agam\LYSC5
Anopheles gambiae
Malaria mosquito
Agam\LYSC2
Anopheles gambiae
Malaria mosquito
Agam\LYSC7
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ005450
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ005451
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ010731
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ010730
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0K52 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA012264
Bombyx mori
Silkmoth
Bmor\BGIBMGA010439
Bombyx mori
Silkmoth
Bmor\Bmo.6205
Danaus plexippus
Monarch butterfly
Dple\DPOGS202823-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS210298-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS203026-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS210308-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS214912-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL002661
Heliconius melpomene
Postman butterfly
Hmel\HMEL002877
Heliconius melpomene
Postman butterfly
Hmel\HMEL002874
Heliconius melpomene
Postman butterfly
Hmel\HMEL002880
Apis florea
Little honeybee
Aflo\3083936196
Apis florea
Little honeybee
Aflo\3083936228
Apis mellifera
Western honey bee
Amel\GB40164
Apis mellifera
Western honey bee
Amel\Lys-1
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP17542
Bombus terrestris
Buff-tailed bumblebee
Bter\15205117
Linepithema humile
Argentine ant
Lhum\LH21370
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:0017d1
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG001574
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_12289
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_10301
Tribolium castaneum
Red flour beetle
Tcas\TC032586
Tribolium castaneum
Red flour beetle
Tcas\TC033648
Pediculus humanus
Human body louse
Phum\PHUM563940
Rhodnius prolixus
Kissing bug
Rpro\RPRC015442
Rhodnius prolixus
Kissing bug
Rpro\RPRC015440
Rhodnius prolixus
Kissing bug
Rpro\RPRC015441
Cimex lectularius
Bed bug
Clec\CLEC003819
Cimex lectularius
Bed bug
Clec\CLEC025167
Cimex lectularius
Bed bug
Clec\CLEC013272
Cimex lectularius
Bed bug
Clec\CLEC009914
Cimex lectularius
Bed bug
Clec\CLEC003818
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_03738
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_11184
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_17477
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0KDK )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR003951
Strigamia maritima
European centipede
Smar\SMAR006865
Strigamia maritima
European centipede
Smar\SMAR012086
Strigamia maritima
European centipede
Smar\SMAR006871
Strigamia maritima
European centipede
Smar\SMAR015607
Strigamia maritima
European centipede
Smar\SMAR011759
Strigamia maritima
European centipede
Smar\SMAR006862
Strigamia maritima
European centipede
Smar\SMAR012085
Strigamia maritima
European centipede
Smar\SMAR009782
Strigamia maritima
European centipede
Smar\SMAR005230
Strigamia maritima
European centipede
Smar\SMAR006870
Strigamia maritima
European centipede
Smar\SMAR006868
Strigamia maritima
European centipede
Smar\SMAR003952
Strigamia maritima
European centipede
Smar\SMAR006861
Strigamia maritima
European centipede
Smar\SMAR006872
Strigamia maritima
European centipede
Smar\SMAR006866
Strigamia maritima
European centipede
Smar\SMAR006863
Strigamia maritima
European centipede
Smar\SMAR011763
Strigamia maritima
European centipede
Smar\SMAR011761
Strigamia maritima
European centipede
Smar\SMAR011592
Strigamia maritima
European centipede
Smar\SMAR011758
Strigamia maritima
European centipede
Smar\SMAR007453
Strigamia maritima
European centipede
Smar\SMAR011764
Strigamia maritima
European centipede
Smar\SMAR006869
Strigamia maritima
European centipede
Smar\SMAR001436
Ixodes scapularis
Black-legged tick
Isca\ISCW018431
Ixodes scapularis
Black-legged tick
Isca\ISCW017129
Ixodes scapularis
Black-legged tick
Isca\ISCW001645
Stegodyphus mimosarum
African social velvet spider
Smim\KFM64933.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM60871.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM63541.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur21g01120
Tetranychus urticae
Two-spotted spider mite
Turt\tetur21g02460
Tetranychus urticae
Two-spotted spider mite
Turt\tetur09g04040
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_300634
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0R9V )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000012933
Gallus gallus
Domestic chicken
Ggal\LYZ
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (11)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
LysE
8 of 10
LysB
7 of 10
LysD
7 of 10
LysP
7 of 10
LysX
7 of 10
CG7798
6 of 10
CG16799
6 of 10
CG30062
6 of 10
CG11159
5 of 10
CG16756
5 of 10
CG8492
4 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 1 )
    Human Ortholog
    Disease
    Evidence
    References
    LYZ; lysozyme
    model of  familial visceral amyloidosis
    IEA
    (FlyBase, 2019-)
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    LYZ; lysozyme
    11 of 15
    153450
     
    LYZL1; lysozyme like 1
    7 of 15
        LYZL2; lysozyme like 2
        7 of 15
        612748
             
            SPACA3; sperm acrosome associated 3
            7 of 15
            612749
                LYZL4; lysozyme like 4
                6 of 15
                612750
                    LYZL6; lysozyme like 6
                    6 of 15
                    612751
                        SPACA5B; sperm acrosome associated 5B
                        6 of 15
                            LALBA; lactalbumin alpha
                            5 of 15
                            149750
                                 
                                SPACA5; sperm acrosome associated 5
                                4 of 15
                                300593
                                    Functional Complementation Data
                                    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
                                    Interactions
                                    Summary of Physical Interactions
                                    esyN Network Diagram
                                    Interactions Browser
                                    Summary of Genetic Interactions
                                    esyN Network Diagram
                                    Starting gene(s)
                                    Interaction type
                                    Interacting gene(s)
                                    Reference
                                    Starting gene(s)
                                    Interaction type
                                    Interacting gene(s)
                                    Reference
                                    External Data
                                    Linkouts
                                    DroID - A comprehensive database of gene and protein interactions.
                                    InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
                                    Pathways
                                    Signaling Pathways (FlyBase)
                                    Metabolic Pathways
                                    External Data
                                    Linkouts
                                    Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                                    Genomic Location and Detailed Mapping Data
                                    Chromosome (arm)
                                    3L
                                    Recombination map

                                    3-0

                                    Cytogenetic map
                                    61F4-61F4
                                    Sequence location
                                    3L:1,227,747..1,228,238 [+]
                                    FlyBase Computed Cytological Location
                                    Cytogenetic map
                                    Evidence for location
                                    61F4-61F4
                                    Limits computationally determined from genome sequence between P{PZ}l(3)0596705967 and P{PZ}l(3)0264002640
                                    Experimentally Determined Cytological Location
                                    Cytogenetic map
                                    Notes
                                    References
                                    Experimentally Determined Recombination Data
                                    Location

                                    3-0

                                    (FlyBase, 2016)

                                    3-1.5

                                    (Comeron et al., 2012)
                                    Left of (cM)
                                    Right of (cM)
                                    Notes
                                    Stocks and Reagents
                                    Stocks (3)
                                    Genomic Clones (16)
                                     

                                    Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

                                    cDNA Clones (11)
                                     

                                    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

                                    cDNA clones, fully sequenced
                                    BDGP DGC clones
                                    Other clones
                                    Drosophila Genomics Resource Center cDNA clones

                                    For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

                                    cDNA Clones, End Sequenced (ESTs)
                                    BDGP DGC clones
                                    Other clones
                                      RNAi and Array Information
                                      Linkouts
                                      DRSC - Results frm RNAi screens
                                      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                                      Antibody Information
                                      Laboratory Generated Antibodies
                                       
                                      Commercially Available Antibodies
                                       
                                      Other Information
                                      Relationship to Other Genes
                                      Source for database identify of
                                      Source for database merge of

                                      Source for merge of: LysS BcDNA:LP06719

                                      (FlyBase, 1996-)
                                      Additional comments

                                      Source for merge of LysS BcDNA:LP06719 was a shared cDNA ( date:030728 ).

                                      (FlyBase, 1996-)
                                      Other Comments

                                      Lysozymes are expressed at a high level mainly in the digestive tract, they are not a component of the haemolymph. Lysozyme is not induced by bacteria so is not part of the inducible immune response but instead has been recruited for digestion of symbiotic bacteria in the stomach.

                                      (Daffre et al., 1994)
                                      Origin and Etymology
                                      Discoverer
                                      Etymology
                                      Identification
                                      External Crossreferences and Linkouts ( 33 )
                                      Sequence Crossreferences
                                      NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                                      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                                      GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                                      RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                                      UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
                                      Other crossreferences
                                      BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
                                      Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
                                      Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
                                      Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
                                      Flygut - An atlas of the Drosophila adult midgut
                                      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                                      InterPro - A database of protein families, domains and functional sites
                                      KEGG Genes - Molecular building blocks of life in the genomic space.
                                      modMine - A data warehouse for the modENCODE project
                                      Linkouts
                                      DroID - A comprehensive database of gene and protein interactions.
                                      DRSC - Results frm RNAi screens
                                      FLIGHT - Cell culture data for RNAi and other high-throughput technologies
                                      FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
                                      FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
                                      FlyMine - An integrated database for Drosophila genomics
                                      InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
                                      Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                                      Synonyms and Secondary IDs (6)
                                      Datasets (0)
                                      Study focus (0)
                                      Experimental Role
                                      Project
                                      Project Type
                                      Title
                                      References (42)