UbcD6, Dhr6, Rad6, dRad6
Gene model reviewed during 5.47
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.39
Gene model reviewed during 5.53
151 (aa); 17 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ubc6 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Ubc6 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: UbcD6 BcDNA:RE56673
Renamed from 'UbcD6' to 'Ubc6' as the 'D' indicates 'Drosophila' (which FlyBase nomenclature rules disallow).
Source for merge of UbcD6 BcDNA:RE56673 was a shared cDNA ( date:030728 ).
UbcD6 increases the UV resistance of S.cerevisiae Scer\rad6 mutant cells, although not to wild-type levels. The γ ray sensitivity of S.cerevisiae Scer\rad6 mutant cells is also complemented by UbcD6, to almost wild-type levels. The sporulation defect of S.cerevisiae Scer\rad6 mutant cells is not rescued by UbcD6.
RNAi screen using dsRNA made from templates generated with primers directed against this gene causes defects in the formation of monastral bipolar spindles when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA.
RNAi screen using dsRNA made from templates generated with primers directed against this gene in S2 cells does not affect the number of prophase centrosomes, but monastral bipolar spindles are formed during mitosis, suggesting that the centrosomes are fused.
Area matching Drosophila RAD6 gene, Acc. No. M63792.