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Gene Dmel\Su(P)

General Information
Symbol	Dmel\Su(P)	Species	D. melanogaster
Name	Suppressor of ref(2)P sterility	Annotation symbol	CG4086
Feature type	protein_coding_gene	FlyBase ID	FBgn0004465
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map	3-44
Cytogenetic map	73B1-73B1	Sequence location	3L:16,603,762..16,605,299 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Suppressor of ref(2)P sterility is referred to in FlyBase by the symbol Dmel\Su(P) (CG4086, FBgn0004465). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: protein disulfide oxidoreductase activity; electron carrier activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: cell redox homeostasis. 15 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Glutaredoxin; Glutaredoxin active site; Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Thioredoxin-like fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages, during early larval stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1635950_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Su(P). Gene sequence location is 3L:16603762..16605299.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 73B1-73B1   Limits computationally determined from genome sequence between P{lacW}l(3)j10E8j10E8&P{PZ}l(3)1053210532 and P{PZ}Baldspot02281
Experimentally Determined Cytological Location
Cytogenetic map Notes References 73B1-73B2   (determined by in situ hybridisation)   (Bichon et al., 2001) 73B1-73B2     (Contamine, 1998.9.17)
Experimentally Determined Recombination Data
Location	3-44   3-44.1 (Bichon et al., 2001)
Left of (cM)	db (Bichon et al., 2001)
Right of (cM)	st (Bichon et al., 2001)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Su(P) for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45 Variant designated Su(P)[R5.1]. The sequenced genome has the A to C substitution and the 32 base insertion reported for Su(P)[pr26] and Su(P)[pe] alleles. At least one of these molecular changes is thought to be responsible for the difference between supressor and non-supressor variants. (FBrf0137024).
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Su(P)-RA FBtr0075359  NM_079392   1412   417
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Su(P)-PA   FBpp0075118   47.1   417   9.36     NP_524116   AAF49434
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Glutaredoxin (IPR002109) Glutathione S-transferase, C-terminal-like (IPR010987) Glutaredoxin active site (IPR011767) Thioredoxin-like fold (IPR012336) Glutathione S-transferase, C-terminal (IPR004046)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF49434   AJ011320 CAA09595   AJ250305 CAB58345   AJ250306 CAB58347   AJ250307 CAB58349   AY070681 AAL48152   BI368371   BI368379   BI372392   BI372440   BI375969   BI568951   BI568952   BI569539   BI574297   BI574867   BI580030   BI581967   BI582530   BI589541   BI589679   BI589680   BI590387   BI593264   BI609058   BI609215   BI609934   BI611410   BI612735   BI615111   BI615195   BI615213   BI616107   BI620248   BI620815   BI622281   BI630236   BI635294   BT044124   CK134835   CL943564   CO281574   CO294101   CO314903   CO339486   EC088385   EC222359   EC224364   EC239417   EC255525   EV575703   EV584732   GH747728   GH747904   GH749489   GH751368   GH754542   GH755717   GH756937   GH756981   GH759666   GH760246   GH760970   GH770385   GH770516   GH775737   GH776622   GH776702   GH777099   GH778247   GH781597   GH784691   GH784839   GH785240   GH785477   GH786747   GH788738   GH789362   GH792965   GH794969   GH798978   GH801811   GH804353   GH806039   GH807751   GH811145   GH811831   GH814745   GH816723   GH818231   GH821801   GH822283   GH824252   GH828629   GH830428   GH833580   GH834010   GH835621   GH836748   GH837429   GH837775   GH838997   GH839273   GH841883   GH843729   GH843779   GH847185   GH847636   GH849304   GH849510   GH849895   GH850665   GH850954   GH853441   GH854546   GH855634   GH855921   GH859016   GH859750   GH860769   GH865129   GH865453   GH867717   GH870545   GH873475   GH874731   GH878254   GH878332   GH880492   GH881132   GH881979   GH883064   GH884835   GH889079   GH890237   GH890665   GH891110   GH891789   GH891996   GH894835   GH894975   GH896580   GH907450   GH913077   GH914331   GH919299   GH921433   GH921574   GH921715   GH922003   GH927636   GH929387   GH930369   GH930832   GH931742   GH932116   GH933860   GH934305   GH935217   GH935827   GH937235   GH937275
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9V420 O77287 Q9U5V9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References insertion site P{}Su(P)[hd5] 3L:16,605,198..16,605,369 comment=The insertion site was localized to a BstEII-NheI restriction fragment; the position of the restriction fragment on the reference sequence was inferred by a FlyBase curator. The orientation of the insertion was not reported. evidence=experimental linked_to=BstEII-NheI_rfrag (Bichon et al., 2001) insertion site P{}Su(P)[hd48] 3L:16,603,910..16,604,169 comment=The insertion site was localized to an AatII restriction fragment; the position of the restriction fragment on the reference sequence was inferred by a FlyBase curator. The orientation of the insertion was not reported. evidence=experimental linked_to=AatII-AatII_rfrag (Bichon et al., 2001)
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | faint & ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | faint & ubiquitous   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | faint & ubiquitous   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 13 -- 16   dorsal pharyngeal muscle   (Fisher et al., 2012) embryonic brain   (Fisher et al., 2012) embryonic midgut chamber   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) embryonic/larval muscle system   (Fisher et al., 2012) embryonic/larval somatic muscle   (Fisher et al., 2012) embryonic/larval visceral muscle   (Fisher et al., 2012) gonad   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) ventral nerve cord   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    280.85 Larval Midgut    145.3 Larval Hindgut    237.6 Larval Malpighian Tubules    163.9 Larval Fat Body    120.4 Larval Salivary Gland    184.6 Larval Trachea    185.6 Larval Carcass    176.525 Adult Head    164.7 Adult Eye    182.2 Adult Brain    229.5 Adult Thoracic-Abdominal Ganglion    235.7 Adult Crop    141.7 Adult Midgut    126.1 Adult Hindgut    288.1 Adult Malpighian Tubules    208.4 Adult Fat Body    143.9 Adult Salivary Gland    228.3 Adult Heart    199.55 Adult VirginFemale Spermatheca    147.1 Adult InseminatedFemale Spermatheca    148.4 Adult Ovary    251.2 Adult Testis    58.2 Adult Male Accessory Gland    171.5 Adult Carcass    185.6 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    280.85 Larval Midgut    145.3 Larval Hindgut    237.6 Larval Malpighian Tubules    163.9 Larval Fat Body    120.4 Larval Salivary Gland    184.6 Larval Trachea    185.6 Larval Carcass    176.525 Adult Head    164.7 Adult Eye    182.2 Adult Brain    229.5 Adult Thoracic-Abdominal Ganglion    235.7 Adult Crop    141.7 Adult Midgut    126.1 Adult Hindgut    288.1 Adult Malpighian Tubules    208.4 Adult Fat Body    143.9 Adult Salivary Gland    228.3 Adult Heart    199.55 Adult VirginFemale Spermatheca    147.1 Adult InseminatedFemale Spermatheca    148.4 Adult Ovary    251.2 Adult Testis    58.2 Adult Male Accessory Gland    171.5 Adult Carcass    185.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    280.85 Larval Midgut    145.3 Larval Hindgut    237.6 Larval Malpighian Tubules    163.9 Larval Fat Body    120.4 Larval Salivary Gland    184.6 Larval Trachea    185.6 Larval Carcass    176.525 Adult Head    164.7 Adult Eye    182.2 Adult Brain    229.5 Adult Thoracic-Abdominal Ganglion    235.7 Adult Crop    141.7 Adult Midgut    126.1 Adult Hindgut    288.1 Adult Malpighian Tubules    208.4 Adult Fat Body    143.9 Adult Salivary Gland    228.3 Adult Heart    199.55 Adult VirginFemale Spermatheca    147.1 Adult InseminatedFemale Spermatheca    148.4 Adult Ovary    251.2 Adult Testis    58.2 Adult Male Accessory Gland    171.5 Adult Carcass    185.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    280.85 Larval Midgut    145.3 Larval Hindgut    237.6 Larval Malpighian Tubules    163.9 Larval Fat Body    120.4 Larval Salivary Gland    184.6 Larval Trachea    185.6 Larval Carcass    176.525 Adult Head    164.7 Adult Eye    182.2 Adult Brain    229.5 Adult Thoracic-Abdominal Ganglion    235.7 Adult Crop    141.7 Adult Midgut    126.1 Adult Hindgut    288.1 Adult Malpighian Tubules    208.4 Adult Fat Body    143.9 Adult Salivary Gland    228.3 Adult Heart    199.55 Adult VirginFemale Spermatheca    147.1 Adult InseminatedFemale Spermatheca    148.4 Adult Ovary    251.2 Adult Testis    58.2 Adult Male Accessory Gland    171.5 Adult Carcass    185.6 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    280.85 Larval Midgut    145.3 Larval Hindgut    237.6 Larval Malpighian Tubules    163.9 Larval Fat Body    120.4 Larval Salivary Gland    184.6 Larval Trachea    185.6 Larval Carcass    176.525 Adult Head    164.7 Adult Eye    182.2 Adult Brain    229.5 Adult Thoracic-Abdominal Ganglion    235.7 Adult Crop    141.7 Adult Midgut    126.1 Adult Hindgut    288.1 Adult Malpighian Tubules    208.4 Adult Fat Body    143.9 Adult Salivary Gland    228.3 Adult Heart    199.55 Adult VirginFemale Spermatheca    147.1 Adult InseminatedFemale Spermatheca    148.4 Adult Ovary    251.2 Adult Testis    58.2 Adult Male Accessory Gland    171.5 Adult Carcass    185.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    280.85 Larval Midgut    145.3 Larval Hindgut    237.6 Larval Malpighian Tubules    163.9 Larval Fat Body    120.4 Larval Salivary Gland    184.6 Larval Trachea    185.6 Larval Carcass    176.525 Adult Head    164.7 Adult Eye    182.2 Adult Brain    229.5 Adult Thoracic-Abdominal Ganglion    235.7 Adult Crop    141.7 Adult Midgut    126.1 Adult Hindgut    288.1 Adult Malpighian Tubules    208.4 Adult Fat Body    143.9 Adult Salivary Gland    228.3 Adult Heart    199.55 Adult VirginFemale Spermatheca    147.1 Adult InseminatedFemale Spermatheca    148.4 Adult Ovary    251.2 Adult Testis    58.2 Adult Male Accessory Gland    171.5 Adult Carcass    185.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    280.85 Larval Midgut    145.3 Larval Hindgut    237.6 Larval Malpighian Tubules    163.9 Larval Fat Body    120.4 Larval Salivary Gland    184.6 Larval Trachea    185.6 Larval Carcass    176.525 Adult Head    164.7 Adult Eye    182.2 Adult Brain    229.5 Adult Thoracic-Abdominal Ganglion    235.7 Adult Crop    141.7 Adult Midgut    126.1 Adult Hindgut    288.1 Adult Malpighian Tubules    208.4 Adult Fat Body    143.9 Adult Salivary Gland    228.3 Adult Heart    199.55 Adult VirginFemale Spermatheca    147.1 Adult InseminatedFemale Spermatheca    148.4 Adult Ovary    251.2 Adult Testis    58.2 Adult Male Accessory Gland    171.5 Adult Carcass    185.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    280.85 Larval Midgut    145.3 Larval Hindgut    237.6 Larval Malpighian Tubules    163.9 Larval Fat Body    120.4 Larval Salivary Gland    184.6 Larval Trachea    185.6 Larval Carcass    176.525 Adult Head    164.7 Adult Eye    182.2 Adult Brain    229.5 Adult Thoracic-Abdominal Ganglion    235.7 Adult Crop    141.7 Adult Midgut    126.1 Adult Hindgut    288.1 Adult Malpighian Tubules    208.4 Adult Fat Body    143.9 Adult Salivary Gland    228.3 Adult Heart    199.55 Adult VirginFemale Spermatheca    147.1 Adult InseminatedFemale Spermatheca    148.4 Adult Ovary    251.2 Adult Testis    58.2 Adult Male Accessory Gland    171.5 Adult Carcass    185.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    164.7   NA  Eye    182.2   NA  Brain    229.5   280.85  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    235.7   NA  Crop    141.7   145.3  Midgut    126.1   237.6  Hindgut    288.1   163.9  Malpighian Tubules    208.4   120.4  Fat Body    143.9   184.6  Salivary Gland    228.3   NA  Heart    199.55   185.6  Trachea    NA   NA  VirginFemale Spermatheca    147.1   NA  InseminatedFemale Spermatheca    148.4   NA  Ovary    251.2   NA  Testis    58.2   NA  Male Accessory Gland    171.5   176.525  Carcass    185.6 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    11 central nervous system, larvae L3    12 central nervous system, pupae P8    10 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    6 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    6 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    10 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    10 digestive system, 4-day adult    8 digestive system, 20-day adult    9 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    11 carcass, larvae L3 wandering    8 carcass, 1-day adult    7 carcass, 4-day adult    9 carcass, 20-day adult    7 ovary, virgin 4-day female    17 ovary, mated 4-day female    15 testis, mated 4-day male    13 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    11 central nervous system, larvae L3    12 central nervous system, pupae P8    10 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    6 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    6 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    10 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    10 digestive system, 4-day adult    8 digestive system, 20-day adult    9 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    11 carcass, larvae L3 wandering    8 carcass, 1-day adult    7 carcass, 4-day adult    9 carcass, 20-day adult    7 ovary, virgin 4-day female    17 ovary, mated 4-day female    15 testis, mated 4-day male    13 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    11 central nervous system, larvae L3    12 central nervous system, pupae P8    10 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    6 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    6 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    10 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    10 digestive system, 4-day adult    8 digestive system, 20-day adult    9 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    11 carcass, larvae L3 wandering    8 carcass, 1-day adult    7 carcass, 4-day adult    9 carcass, 20-day adult    7 ovary, virgin 4-day female    17 ovary, mated 4-day female    15 testis, mated 4-day male    13 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    11 central nervous system, larvae L3    12 central nervous system, pupae P8    10 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    6 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    6 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    10 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    10 digestive system, 4-day adult    8 digestive system, 20-day adult    9 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    11 carcass, larvae L3 wandering    8 carcass, 1-day adult    7 carcass, 4-day adult    9 carcass, 20-day adult    7 ovary, virgin 4-day female    17 ovary, mated 4-day female    15 testis, mated 4-day male    13 accessory gland, mated 4-day male    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    11 central nervous system, larvae L3    12 central nervous system, pupae P8    10 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    6 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    6 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    10 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    10 digestive system, 4-day adult    8 digestive system, 20-day adult    9 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    11 carcass, larvae L3 wandering    8 carcass, 1-day adult    7 carcass, 4-day adult    9 carcass, 20-day adult    7 ovary, virgin 4-day female    17 ovary, mated 4-day female    15 testis, mated 4-day male    13 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    11 central nervous system, larvae L3    12 central nervous system, pupae P8    10 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    6 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    6 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    10 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    10 digestive system, 4-day adult    8 digestive system, 20-day adult    9 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    11 carcass, larvae L3 wandering    8 carcass, 1-day adult    7 carcass, 4-day adult    9 carcass, 20-day adult    7 ovary, virgin 4-day female    17 ovary, mated 4-day female    15 testis, mated 4-day male    13 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    11 central nervous system, larvae L3    12 central nervous system, pupae P8    10 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    6 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    6 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    10 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    10 digestive system, 4-day adult    8 digestive system, 20-day adult    9 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    11 carcass, larvae L3 wandering    8 carcass, 1-day adult    7 carcass, 4-day adult    9 carcass, 20-day adult    7 ovary, virgin 4-day female    17 ovary, mated 4-day female    15 testis, mated 4-day male    13 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    11 central nervous system, larvae L3    12 central nervous system, pupae P8    10 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    6 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    6 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    10 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    10 digestive system, 4-day adult    8 digestive system, 20-day adult    9 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    11 carcass, larvae L3 wandering    8 carcass, 1-day adult    7 carcass, 4-day adult    9 carcass, 20-day adult    7 ovary, virgin 4-day female    17 ovary, mated 4-day female    15 testis, mated 4-day male    13 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages, during early larval stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    65 embryo 02-04hr    32 embryo 04-06hr    42 embryo 06-08hr    37 embryo 08-10hr    36 embryo 10-12hr    50 embryo 12-14hr    25 embryo 14-16hr    29 embryo 16-18hr    28 embryo 18-20hr    34 embryo 20-22hr    45 embryo 22-24hr    39 larva L1    55 larva L2    51 larva L3 12hr old    43 larva L3 puffstage 1-2    24 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    21 white prepupae 24hr    23 pupae 2d postWPP    35 pupae 3d postWPP    47 pupae 4d postWPP    37 adult male 01day    34 adult male 05day    30 adult male 30day    27 adult female 01day    48 adult female 05day    53 adult female 30day    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (65) embryo 02-04hr  (32) embryo 04-06hr  (42) embryo 06-08hr  (37) embryo 08-10hr  (36) embryo 10-12hr  (50) embryo 12-14hr    25 embryo 14-16hr  (29) embryo 16-18hr  (28) embryo 18-20hr  (34) embryo 20-22hr  (45) embryo 22-24hr  (39) larva L1  (55) larva L2  (51) larva L3 12hr old  (43) larva L3 puffstage 1-2    24 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    21 white prepupae 24hr    23 pupae 2d postWPP  (35) pupae 3d postWPP  (47) pupae 4d postWPP  (37) adult male 01day  (34) adult male 05day  (30) adult male 30day  (27) adult female 01day  (48) adult female 05day  (53) adult female 30day  (53) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    65 embryo 02-04hr    32 embryo 04-06hr    42 embryo 06-08hr    37 embryo 08-10hr    36 embryo 10-12hr    50 embryo 12-14hr    25 embryo 14-16hr    29 embryo 16-18hr    28 embryo 18-20hr    34 embryo 20-22hr    45 embryo 22-24hr    39 larva L1    55 larva L2    51 larva L3 12hr old    43 larva L3 puffstage 1-2    24 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    21 white prepupae 24hr    23 pupae 2d postWPP    35 pupae 3d postWPP    47 pupae 4d postWPP    37 adult male 01day    34 adult male 05day    30 adult male 30day    27 adult female 01day    48 adult female 05day    53 adult female 30day    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    65 embryo 02-04hr    32 embryo 04-06hr    42 embryo 06-08hr    37 embryo 08-10hr    36 embryo 10-12hr    50 embryo 12-14hr    25 embryo 14-16hr    29 embryo 16-18hr    28 embryo 18-20hr    34 embryo 20-22hr    45 embryo 22-24hr    39 larva L1    55 larva L2    51 larva L3 12hr old    43 larva L3 puffstage 1-2    24 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    21 white prepupae 24hr    23 pupae 2d postWPP    35 pupae 3d postWPP    47 pupae 4d postWPP    37 adult male 01day    34 adult male 05day    30 adult male 30day    27 adult female 01day    48 adult female 05day    53 adult female 30day    53 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    65 embryo 02-04hr    32 embryo 04-06hr    42 embryo 06-08hr    37 embryo 08-10hr    36 embryo 10-12hr    50 embryo 12-14hr    25 embryo 14-16hr    29 embryo 16-18hr    28 embryo 18-20hr    34 embryo 20-22hr    45 embryo 22-24hr    39 larva L1    55 larva L2    51 larva L3 12hr old    43 larva L3 puffstage 1-2    24 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    21 white prepupae 24hr    23 pupae 2d postWPP    35 pupae 3d postWPP    47 pupae 4d postWPP    37 adult male 01day    34 adult male 05day    30 adult male 30day    27 adult female 01day    48 adult female 05day    53 adult female 30day    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (65) embryo 02-04hr  32 embryo 04-06hr  (42) embryo 06-08hr  (37) embryo 08-10hr  (36) embryo 10-12hr  (50) embryo 12-14hr    25 embryo 14-16hr  29 embryo 16-18hr  28 embryo 18-20hr  (34) embryo 20-22hr  (45) embryo 22-24hr  (39) larva L1  (55) larva L2  (51) larva L3 12hr old  (43) larva L3 puffstage 1-2    24 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    21 white prepupae 24hr    23 pupae 2d postWPP  (35) pupae 3d postWPP  (47) pupae 4d postWPP  (37) adult male 01day  (34) adult male 05day  30 adult male 30day  27 adult female 01day  (48) adult female 05day  (53) adult female 30day  (53) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    65 embryo 02-04hr    32 embryo 04-06hr    42 embryo 06-08hr    37 embryo 08-10hr    36 embryo 10-12hr    50 embryo 12-14hr    25 embryo 14-16hr    29 embryo 16-18hr    28 embryo 18-20hr    34 embryo 20-22hr    45 embryo 22-24hr    39 larva L1    55 larva L2    51 larva L3 12hr old    43 larva L3 puffstage 1-2    24 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    21 white prepupae 24hr    23 pupae 2d postWPP    35 pupae 3d postWPP    47 pupae 4d postWPP    37 adult male 01day    34 adult male 05day    30 adult male 30day    27 adult female 01day    48 adult female 05day    53 adult female 30day    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    65 embryo 02-04hr    32 embryo 04-06hr    42 embryo 06-08hr    37 embryo 08-10hr    36 embryo 10-12hr    50 embryo 12-14hr    25 embryo 14-16hr    29 embryo 16-18hr    28 embryo 18-20hr    34 embryo 20-22hr    45 embryo 22-24hr    39 larva L1    55 larva L2    51 larva L3 12hr old    43 larva L3 puffstage 1-2    24 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    21 white prepupae 24hr    23 pupae 2d postWPP    35 pupae 3d postWPP    47 pupae 4d postWPP    37 adult male 01day    34 adult male 05day    30 adult male 30day    27 adult female 01day    48 adult female 05day    53 adult female 30day    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    54 Schneider line 2 Sg4    62 embryonic 1182-4H    20 embryonic GM2    22 embryonic Kc167    24 embryonic S1    33 embryonic S3    22 leg disc CME L1    55 wing disc CME-W2    17 wing disc ML-DmD8    26 wing disc ML-DmD9    28 wing disc ML-DmD16-c3    23 wing disc ML-DmD21    61 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    35 mixed discs ML-DmD4-c1    40 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    27 tumorous blood cells mbn2    16 ovary fGS/OSS    14 ovary OSC    9 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (54) Schneider line 2 Sg4  (62) embryonic 1182-4H    20 embryonic GM2    22 embryonic Kc167    24 embryonic S1  (33) embryonic S3    22 leg disc CME L1  (55) wing disc CME-W2    17 wing disc ML-DmD8  26 wing disc ML-DmD9  (28) wing disc ML-DmD16-c3    23 wing disc ML-DmD21  (61) wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11  (27) antennal disc ML-DmD20-c5  (35) mixed discs ML-DmD4-c1  (40) CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2  (27) tumorous blood cells mbn2    16 ovary fGS/OSS    14 ovary OSC    9 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    54 Schneider line 2 Sg4    62 embryonic 1182-4H    20 embryonic GM2    22 embryonic Kc167    24 embryonic S1    33 embryonic S3    22 leg disc CME L1    55 wing disc CME-W2    17 wing disc ML-DmD8    26 wing disc ML-DmD9    28 wing disc ML-DmD16-c3    23 wing disc ML-DmD21    61 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    35 mixed discs ML-DmD4-c1    40 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    27 tumorous blood cells mbn2    16 ovary fGS/OSS    14 ovary OSC    9 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    54 Schneider line 2 Sg4    62 embryonic 1182-4H    20 embryonic GM2    22 embryonic Kc167    24 embryonic S1    33 embryonic S3    22 leg disc CME L1    55 wing disc CME-W2    17 wing disc ML-DmD8    26 wing disc ML-DmD9    28 wing disc ML-DmD16-c3    23 wing disc ML-DmD21    61 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    35 mixed discs ML-DmD4-c1    40 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    27 tumorous blood cells mbn2    16 ovary fGS/OSS    14 ovary OSC    9 ovary OSS    6 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    54 Schneider line 2 Sg4    62 embryonic 1182-4H    20 embryonic GM2    22 embryonic Kc167    24 embryonic S1    33 embryonic S3    22 leg disc CME L1    55 wing disc CME-W2    17 wing disc ML-DmD8    26 wing disc ML-DmD9    28 wing disc ML-DmD16-c3    23 wing disc ML-DmD21    61 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    35 mixed discs ML-DmD4-c1    40 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    27 tumorous blood cells mbn2    16 ovary fGS/OSS    14 ovary OSC    9 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (54) Schneider line 2 Sg4  (62) embryonic 1182-4H    20 embryonic GM2    22 embryonic Kc167    24 embryonic S1  (33) embryonic S3    22 leg disc CME L1  (55) wing disc CME-W2    17 wing disc ML-DmD8  26 wing disc ML-DmD9  28 wing disc ML-DmD16-c3    23 wing disc ML-DmD21  (61) wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11  27 antennal disc ML-DmD20-c5  (35) mixed discs ML-DmD4-c1  (40) CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2  27 tumorous blood cells mbn2    16 ovary fGS/OSS    14 ovary OSC    9 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    54 Schneider line 2 Sg4    62 embryonic 1182-4H    20 embryonic GM2    22 embryonic Kc167    24 embryonic S1    33 embryonic S3    22 leg disc CME L1    55 wing disc CME-W2    17 wing disc ML-DmD8    26 wing disc ML-DmD9    28 wing disc ML-DmD16-c3    23 wing disc ML-DmD21    61 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    35 mixed discs ML-DmD4-c1    40 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    27 tumorous blood cells mbn2    16 ovary fGS/OSS    14 ovary OSC    9 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    54 Schneider line 2 Sg4    62 embryonic 1182-4H    20 embryonic GM2    22 embryonic Kc167    24 embryonic S1    33 embryonic S3    22 leg disc CME L1    55 wing disc CME-W2    17 wing disc ML-DmD8    26 wing disc ML-DmD9    28 wing disc ML-DmD16-c3    23 wing disc ML-DmD21    61 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    35 mixed discs ML-DmD4-c1    40 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    27 tumorous blood cells mbn2    16 ovary fGS/OSS    14 ovary OSC    9 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    5 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    13 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    19 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    17 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    5 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    13 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    19 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    5 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    13 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    19 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    5 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    13 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    19 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    17 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    5 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    13 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    19 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    5 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    13 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    19 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    5 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    13 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    19 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    5 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    13 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    19 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_19 mE1_20_mRNA_expression_cluster_03
External Data & Images
Linkouts	BDGP expression data • FI02878 RH17614 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0004465 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4086-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Su(P) Stages(s) 1-3 Stages(s) 4-6 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable Su(P)EY13245 viable, with Scer\GAL4pnr-MD237 Su(P)GD6153 Sterility Allele fertile Su(P)EY13245 Phenotype manifest in Allele
Classical Alleles ( 9 )
For All Classical Alleles Show
Allele of Su(P) Class Mutagen Stocks Known lesion Su(P)EY13245 P-element activity 1 -- Su(P)db spontaneous 0 -- Su(P)GlSbH spontaneous 0 -- Su(P)hd48 PM hybrid dysgenesis 0 Yes Su(P)hd5 PM hybrid dysgenesis 0 Yes Su(P)pe spontaneous 0 Yes Su(P)pr26 spontaneous 0 Yes Su(P)TW2 spontaneous 0 -- Su(P)TW9 spontaneous 0 --
Alleles Carried on Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Su(P) Class Mutagen Stocks Known lesion Su(P)GD6153 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes Su(P)HMS00430 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Su(P)HMS00474 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Su(P)+t2.56 in vitro construct - genomic fragment 0 Yes Su(P)KK105683 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes Su(P)NIG.4086R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)st4 (Bichon et al., 2001) Df(3L)st7 (Bichon et al., 2001) Df(3L)st-E23 (Bichon et al., 2001) Df(3L)st-E34 (Bichon et al., 2001) Df(3L)st-E36 (Bichon et al., 2001) Df(3L)st-E46 (Bichon et al., 2001) Df(3L)st-E48 (Bichon et al., 2001) Df(3L)st-E52 (Bichon et al., 2001) Df(3L)st-E53 (Bichon et al., 2001) Df(3L)st-RX9 (Bichon et al., 2001)
Not disrupted in	Df(3L)st-E5 (Bichon et al., 2001)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD6153} NA P{KK105683} NA P{NIG.4086R} NA P{TRiP.HMS00430} NA P{TRiP.HMS00474} NA characterization construct P{Su(P).2.56} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}Su(P)EY13245 NA miscellaneous insertions P{}Su(P)hd5 NA P{}Su(P)hd48 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
electron carrier activity inferred from electronic annotation with InterPro:IPR002109, InterPro:IPR011767 (FlyBase Curators et al., 2004-) protein disulfide oxidoreductase activity inferred from electronic annotation with InterPro:IPR002109 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
cell redox homeostasis inferred from electronic annotation with InterPro:IPR002109, InterPro:IPR011767 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
Su(P) - CG9577 experimental knowledge based (Guruharsha et al., 2011) Su(P) - EndoG experimental knowledge based (Guruharsha et al., 2011) Su(P) - Iap2 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) Su(P) - mtDNA-helicase experimental knowledge based (Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Su(P) allele Gene References Su(P)db ref(2)P (Bichon et al., 2001) Su(P)GlSbH ref(2)P (Bichon et al., 2001) Su(P)TW2 ref(2)P (Bichon et al., 2001) Su(P)TW9 ref(2)P (Bichon et al., 2001) unspecified ref(2)P (Bichon et al., 2001)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 65156 DroID - A comprehensive database of gene and protein interactions. • FBgn0004465 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39856
Orthologs
OrthoDB Orthologs (42) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6321J3 Dipteran inclusive ortholog search EOG6TQMJQ Insect inclusive ortholog search EOG62JMN9 Arthropod inclusive ortholog search EOG6J9KFQ Metazoa inclusive ortholog search EOG6KWXMS
Orthologs in Drosophila Species (EOG6321J3)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Su(P)     Drosophila simulans   Dsim\Su(P) Y   Drosophila sechellia   Dsec\GM24381 Y   Drosophila erecta   Dere\Su(P) Y   Drosophila yakuba   Dyak\GE22204 Y   Drosophila ananassae   Dana\GF10514 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA17946 Y   Drosophila persimilis   Dper\GL12723 Y   Drosophila willistoni   Dwil\GK20317 Y   Drosophila virilis   Dvir\GJ12456 Y   Drosophila mojavensis   Dmoj\GI16712 Y   Drosophila grimshawi   Dgri\GH16457 Y
Orthologs in non-Drosophila Dipterans (EOG6TQMJQ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL008783   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL008776   Anopheles gambiae Malaria mosquito  Agam\AGAP004992   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ003988   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ018524
Orthologs in non-Dipteran Insects (EOG62JMN9)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB50925   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG016432   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH21176   Atta cephalotes Leafcutter ant  Acep\ACEP17514   Camponotus floridanus Florida carpenter ant  Cflo\CFLO13888   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL23638   Linepithema humile Argentine ant  Lhum\LH12410   Pogonomyrmex barbatus Red harvester ant  Pbar\PB15772   Solenopsis invicta Red fire ant  Sinv\SINV25621   Solenopsis invicta Red fire ant  Sinv\SINV20839   Acyrthosiphon pisum Pea aphid  Apim\ACYPI003398   Acyrthosiphon pisum Pea aphid  Apim\ACYPI089513   Bombyx mori Silkmoth  Bmor\BGIBMGA000723   Pediculus humanus Human body louse  Phum\PHUM580720   Tribolium castaneum Red flour beetle  Tcas\TC003180
Orthologs in non-Insect Arthropods (EOG6J9KFQ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\Mettl3   Ixodes scapularis Deer tick  Isca\ISCW020922
Orthologs in non-Arthropod Metazoa (EOG6KWXMS)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\R11A8.5   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_024702gn   Danio rerio Zebrafish  Drer\ptgesl   Xenopus tropicalis Western clawed frog  Xtro\ptges2   Gallus gallus Domestic chicken  Ggal\PTGES2   Mus musculus House mouse  Mmus\Ptges2   Rattus norvegicus Norway rat  Rnor\Ptges2   Homo sapiens Human  Hsap\PTGES2
Human Orthologs (1)
Gene OMIM HGNC Hsap\PTGES2
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\Su(P) Drosophila sechellia Dsec\GM24381 Drosophila erecta Dere\Su(P) Drosophila yakuba Dyak\GE22204 Drosophila ananassae Dana\GF10514 Drosophila pseudoobscura pseudoobscura Dpse\GA17946 Drosophila persimilis Dper\GL12723 Drosophila willistoni Dwil\GK20317 Drosophila virilis Dvir\GJ12456 Drosophila mojavensis Dmoj\GI16712 Drosophila grimshawi Dgri\GH16457
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	20866 y1 w67c23; P{EPgy2}Su(P)EY13245 32474 y1 sc* v1; P{TRiP.HMS00474}attP2 34955 y1 sc* v1; P{TRiP.HMS00430}attP2
VDRC	v14268 w1118; P{GD6153}v14268/CyO v14269 w1118; P{GD6153}v14269/CyO
Genomic Clones ( 1 )
	BACR11G05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 153 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RH17614
Other clones	FI02878
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RE54332 RE54344 RE59344 RE59395 RE63883 RE74151 RH01634 RH02977 RH03150 RH03151 RH11254 RH13793 RH13968 RH14785 RH19825 RH20763 RH23062 RH27408 RH41681 RH44647 RH44767 RH44788 RH45972 RH51333 RH52049 RH54124 RH59238 SD16601
Other clones	42788 74899 118672 191865 214575.37 Dmel_dig_015684_0618_2767 Dmel_dig_016988_0625_1406 EK157460 EK206012 EK238263 EP02115 RH01204 RH04006 RP003001247 RP003003345 RP003009303 RP003022530 RP003030304 RP003036807 RP003046802 RP003051956 RP003062298 RP003070192 RP003075308 RP003079949 RP003106161 RP003113292 RP003114677 RP003119554 RP003126507 RP003131183 RP003149915 RP003154298 RP003170888 RP003176843 RP003188381 RP003189109 RP003197209 RP003200277 RP003202613 RP003203576 RP003204835 RP003209202 RP003221284 RP003223493 RP003224936 RP003234061 RP003246866 RP003250337 RP003254637 RP003261786 RP003276451 RP003280524 RP003286284 RP003296083 RP003299897 RP003304873 RP003308654 RP003311050 RP003312667 RP003317019 RP003317680 RP003330902 RP003335237 RP003335335 RP003339595 RP003355779 RP003362292 RP003379656 RP003390404 RP003394521 RP003395022 RP003408240 RP003419146 RP003422965 RP003426409 RP003427877 RP003436680 RP003438743 RP003442303 RP003448906 RP003455366 RP003461501 RP003463158 RP003469417 RP003473281 RP003476889 RP003478495 RP003483999 RP003489904 RP003494563 RP003505888 RP003507460 RP003516848 RP003527634 RP003529394 RP003531057 RP003531511 RP003538059 RP003544315 RP003551921 RP003557329 RP003561446 RP003566198 RP003567769 RP003571204 RP003576019 RP003579314 RP003584740 RP003586847 RP003589010 RP003597760 RP003609363 RP003627754 RP003633335 RP003634491 RP003641105 RP003653977 RP003659461 RP003671641 RP003671773 RP003673757 RP003674531
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0004465 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39856
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079392 RefSeq (Proteins) • NP_524116 DDBJ / EMBL / GenBank • AAF49434 AAL48152 AJ011320 AJ250305 AJ250306 AJ250307 AY070681 BI611410 CAA09595 CAB58345 CAB58347 CAB58349 CL943564 Entrez Gene - A searchable database of RefSeq genes. • 39856 UniProtKB/TrEMBL • O77287 Q9U5V9 Q9V420
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Glutaredoxin (IPR002109) Glutathione S-transferase, C-terminal-like (IPR010987) Glutaredoxin active site (IPR011767) Thioredoxin-like fold (IPR012336) Glutathione S-transferase, C-terminal (IPR004046) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • FI02878 RH17614
Linkouts
	BioGRID - A database of protein and genetic interactions • 65156 DroID - A comprehensive database of gene and protein interactions. • FBgn0004465 DRSC - Results from RNAi screens. • FBgn0004465 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0004465 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4086-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0004465 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39856 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39856 modMine - Data generated by the modENCODE project. • FBgn0004465
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	CG4086 (Keleman et al., 2009.8.5, Ni et al., 2010.12.1, Ni et al., 2011.7.19) Su(P) (Carre-Mlouka et al., 2007, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym	Suppressor of ref(2)P sterility
Secondary FlyBase IDs
References ( 20 )
Research paper	Carre-Mlouka et al., 2007, Genetics 176(1): 409--419 Control of sigma virus multiplication by the ref(2)P gene of Drosophila melanogaster: An in vivo study of the PB1 domain of Ref(2)P. [FBrf0201044] Bichon et al., 2001, Mol. Genet. Genomics 265(2): 354--361 Genetic and molecular features of Su(P), a gene that interacts with ref(2)P in male fertility of Drosophila melanogaster. [FBrf0137024]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] Guruharsha et al., 2011, Cell 147(3): Table S3. [FBrf0218395] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Ni et al., 2011.7.19, TRiP germline vector pVALIUM21. TRiP germline vector pVALIUM21. [FBrf0214641] Ni et al., 2010.12.1, A genome-scale shRNA resource for transgenic RNAi in Drosophila. A genome-scale shRNA resource for transgenic RNAi in Drosophila. [FBrf0212437] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]
DNA/RNA sequence record	Contamine, 1999.10.13, GenBank/EMBL/DDBJ: AJ250305 Drosophila melanogaster anon73B1 gene and Su(P) gene, strain pr. [FBrf0114181] Contamine, 1998.9.17, GenBank/EMBL/DDBJ: AJ011320 Drosophila melanogaster Su(P) and anon-73B1 genes and partial o25 gene and Pros26 gene. [FBrf0114178]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]