FB2025_01 , released February 20, 2025
Gene: Dmel\Glyp
Open Close
General Information
Symbol
Dmel\Glyp
Species
D. melanogaster
Name
Glycogen phosphorylase
Annotation Symbol
CG7254
Feature Type
protein_coding_gene
FlyBase ID
FBgn0004507
Gene Model Status
Current
Stock Availability
22 publicly available
Gene Summary
Glycogen phosphorylase (Glyp) encodes an enzyme that catalyzes the phosphorolytic cleavage of glycogen to produce glucose 1-phosphate and thus plays an essential role in glycogen catabolism (glycogenolysis). [Date last reviewed: 2024-09-19] (FlyBase Gene Snapshot)
All Summaries
Also Known As

GP, Glp1

Key Links
Genomic Location
Cytogenetic map
22C3-22D1
Sequence location
Recombination map
2-5
RefSeq locus
NT_033779 REGION:2130813..2137296
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (11 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
enables glycogen phosphorylase activity
inferred from mutant phenotype
(Yamada et al., 2019, Post et al., 2018, Eanes et al., 2006, Tick et al., 1999)
inferred from direct assay
(Dombradi et al., 1986, Dombradi et al., 1985)
enables protein homodimerization activity
inferred from direct assay
(Dombradi et al., 1985)
enables pyridoxal phosphate binding
inferred from direct assay
(Dombradi et al., 1986)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
enables glycogen phosphorylase activity
inferred from electronic annotation with InterPro:IPR000811
(InterPro Project Members, 2004-)
inferred from biological aspect of ancestor with PANTHER:PTN000157685
(GO Reference Genome Project, 2011-)
enables pyridoxal phosphate binding
inferred from biological aspect of ancestor with PANTHER:PTN000157685
(GO Reference Genome Project, 2011-)
inferred from electronic annotation with InterPro:IPR011833
(InterPro Project Members, 2004-)
Biological Process (6 terms)
Terms Based on Experimental Evidence (5 terms)
CV Term
Evidence
References
involved_in defense response to Gram-negative bacterium
inferred from high throughput mutant phenotype
(Cronin et al., 2009)
involved_in determination of adult lifespan
inferred from mutant phenotype
(Post et al., 2018, Bai et al., 2013)
involved_in glycogen catabolic process
inferred from mutant phenotype
(Yamada et al., 2019, Zirin et al., 2013, Eanes et al., 2006, Tick et al., 1999)
involved_in insulin receptor signaling pathway
inferred from mutant phenotype
(Post et al., 2018)
involved_in negative regulation of innate immune response
inferred from high throughput mutant phenotype
(Cronin et al., 2009)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
involved_in carbohydrate metabolic process
inferred from electronic annotation with InterPro:IPR000811, InterPro:IPR011833
(InterPro Project Members, 2004-)
involved_in glycogen catabolic process
inferred from biological aspect of ancestor with PANTHER:PTN000157685
(GO Reference Genome Project, 2011-)
Cellular Component (2 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
located_in cytosol
inferred from direct assay
(Yamada et al., 2019)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
is_active_in cytoplasm
inferred from biological aspect of ancestor with PANTHER:PTN000157685
(GO Reference Genome Project, 2011-)
Gene Group (FlyBase)
Pathway (FlyBase)
Protein Family (UniProt)
Belongs to the glycogen phosphorylase family. (Q9XTL9)
Protein Signatures (InterPro)
Summaries
Gene Snapshot
Glycogen phosphorylase (Glyp) encodes an enzyme that catalyzes the phosphorolytic cleavage of glycogen to produce glucose 1-phosphate and thus plays an essential role in glycogen catabolism (glycogenolysis). [Date last reviewed: 2024-09-19]
Pathway (FlyBase)
Insulin-like Receptor Signaling Pathway Core Components -
The Insulin-like Receptor (IR) signaling pathway in Drosophila is initiated by the binding of an insulin-like peptides to the Insulin-like receptor (InR). (Adapted from FBrf0232297, FBrf0230017 and FBrf0229989.)
GLYCOGEN CATABOLISM -
Glycogen is a highly branched polymer composed of chains of D-glucose linked linearly by α-1,4-glucosidic bonds and joined together by α-1,6-glucosidic bonds between branch points. It is stored in cytosolic granules and serves as an energy source when food supplies are low. Glycogen catabolism involves the cleavage of α-1,4-glucosidic bonds by glycogen phosphorylase Glyp from the non-reducing ends of the linear chain releasing glucose 1-phosphate. The final four glycosyl residues of each branch are removed in two steps by glycogen debranching enzyme Agl. Alternatively, glycogen can be degraded in the lysosomes via an autophagic process known as glycophagy. In D. melanogaster adults, glycogen is primarily catabolized in the fat body and flight muscles to produce glucose and trehalose. (Adapted from FBrf0238357, FBrf0223427 and PMID:22248338.)
Gene Group (FlyBase)
UNCLASSIFIED HEXOSYLTRANSFERASES -
This group comprises hexosyltransferases that do not classify under other groups in FlyBase.
Protein Function (UniProtKB)
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity). Required for glycogen breakdown in skeletal muscle.
(UniProt, Q9XTL9)
Gene Model and Products
Number of Transcripts
2
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\Glyp for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q9XTL9)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Gene model reviewed during 5.47

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Glyp-RA
FBtr0077828
NM_164453
3144
844
Glyp-RB
FBtr0100485
NM_001032048
2891
844
Additional Transcript Data and Comments
Reported size (kB)

3.2, 2.9 (northern blot)

(Tick et al., 1999)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
Glyp-PA
FBpp0077501
97.0
844
6.48
Q9XTL9
NP_722762
AAF51303
Glyp-PB
FBpp0099923
97.0
844
6.48
Q9XTL9
NP_001027219
AAZ66442
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

844 aa isoforms: Glyp-PA, Glyp-PB
Additional Polypeptide Data and Comments
Reported size (kDa)

844 (aa); 97 (kD predicted)

(Tick et al., 1999)
Comments
External Data
Post Translational Modification

Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A.

(UniProt, Q9XTL9)
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Nucleotide / Polypeptide Records
 
UniProt
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Glyp using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.74

Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 1 -- 3
organism

Comment: maternally deposited

(Fisher et al., 2012)
embryonic stage 4 -- 6
organism

Comment: rapidly degraded

(Fisher et al., 2012)
embryonic stage 13 -- 16
larval somatic muscle cell
(Fisher et al., 2012)
northern blot
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage -- adult stage
(Tick et al., 1999)
embryonic stage 1 -- 4

Comment: reference states 0-2 hr AEL

(Tick et al., 1999)
Additional Descriptive Data

2.9kb Glyp transcripts are detected in early embryos.

(Tick et al., 1999)

The 3.2kb Glyp transcript is expressed at all stages tested with the highest levels in early and late embryos, larvae, and adults.

(Tick et al., 1999)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
day 5 of adulthood & male -- day 7 of adulthood & male
spermatozoon
(Dorus et al., 2006)
day 7 of adulthood -- day 49 of adulthood
adult heart
(Cammarato et al., 2011)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in cytosol
inferred from direct assay
(Yamada et al., 2019)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Glyp in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 4-6
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 17 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 11 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Glyp
Transgenic constructs containing regulatory region of Glyp
Aberrations (Deficiencies and Duplications) ( 3 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
partially lethal
partially lethal, with Scer\GAL4elav.PLu
partially lethal, with Scer\GAL4Mef2.PR
partially lethal, with Scer\GAL4Mef2.PR, Scer\GAL4elav.PLu
partially lethal, with Scer\GAL4αTub84B.PL
partially lethal (with Df(2L)ED119)
viable
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4Cg.PA
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4repo
viable, with Scer\GAL4tin.CΔ4
viable, with Scer\GAL4αTub84B.PL
Other Phenotypes
Allele
abnormal developmental rate
abnormal locomotor behavior | adult stage | male | calorie restriction conditional
abnormal mitotic cell cycle | embryonic stage | parental effect, with Scer\GAL4VP16.mat.αTub67C
abnormal starvation stress response, with Scer\GAL4Mef2.PR
abnormal starvation stress response | adult stage
decreased body size | prepupal stage
decreased body size | third instar larval stage
long lived | RU486 conditional, with Scer\GAL4da.Switch.PT
long lived | RU486 conditional, with Scer\GAL4αTub84B.Switch.PK
majority die during larval stage, with Scer\GAL4Mef2.PR
majority die during larval stage, with Scer\GAL4Mef2.PR, Scer\GAL4elav.PLu
majority die during larval stage, with Scer\GAL4αTub84B.PL
short lived
some die during larval stage
some die during larval stage, with Scer\GAL4elav.PLu
some die during larval stage (with Df(2L)ED119)
Phenotype manifest in
Allele
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (3)
Hsap\PYGM
14 of 14
Yes
Yes
1  
Hsap\PYGB
12 of 14
No
Yes
1  
Hsap\PYGL
12 of 14
No
Yes
1  
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (3)
Rnor\Pygm
14 of 14
Yes
Yes
Rnor\Pygb
12 of 14
No
Yes
Rnor\Pygl
12 of 14
No
Yes
Mus musculus (laboratory mouse) (3)
Mmus\Pygm
14 of 14
Yes
Yes
Mmus\Pygl
12 of 14
No
Yes
Mmus\Pygb
11 of 14
No
Yes
Xenopus tropicalis (Western clawed frog) (5)
Xtro\pygb
7 of 13
Yes
Yes
Xtro\pygl
6 of 13
No
Yes
Xtro\pygm
6 of 13
No
Yes
Xtro\sh3bgrl3
1 of 13
No
No
Xtro\zmynd12
1 of 13
No
Yes
Danio rerio (Zebrafish) (4)
Drer\pygma
14 of 14
Yes
Yes
Drer\pygmb
13 of 14
No
Yes
Drer\pygb
12 of 14
No
Yes
Drer\pygl
10 of 14
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (1)
Cele\pygl-1
13 of 14
Yes
Yes
Anopheles gambiae (African malaria mosquito) (1)
Agam\AgaP_AGAP007939
12 of 12
Yes
Yes
Arabidopsis thaliana (thale-cress) (2)
Atha\PHS2
12 of 13
Yes
Yes
Atha\PHS1
11 of 13
No
Yes
Saccharomyces cerevisiae (Brewer's yeast) (1)
Scer\GPH1
12 of 13
Yes
Yes
Schizosaccharomyces pombe (Fission yeast) (0)
Escherichia coli (enterobacterium) (2)
Ecol\glgP
11 of 11
Yes
Yes
Ecol\malP
6 of 11
No
Yes
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:Glyp. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 2 )
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    PYGM; glycogen phosphorylase, muscle associated
    14 of 14
    608455
     
    PYGB; glycogen phosphorylase B
    12 of 14
    138550
         
        PYGL; glycogen phosphorylase L
        12 of 14
        613741
         
        Functional Complementation Data
        Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
        Interactions
        Summary of Physical Interactions
        esyN Network Diagram
        Show neighbor-neighbor interactions:
        Show/hide secondary interactors 
        (data from AllianceMine provided by esyN)
        Select Layout:
        Legend:
        Protein
        RNA
        Selected Interactor(s)
        Other Interaction Browsers
        View in FlyBase Interactions Browser   View in MIST tool (external link)
        Please see the Physical Interaction reports below for full details
        protein-protein
        Physical Interaction
        Assay
        References
        Glyp
        molecular sieving
        (Dombradi et al., 1985)
        Glyp - Adh
        experimental knowledge based
        (Guruharsha et al., 2011)
        Glyp - Ald1
        experimental knowledge based
        (Guruharsha et al., 2011)
        Glyp - Argk1
        experimental knowledge based
        (Guruharsha et al., 2011)
        Glyp - CG16826
        experimental knowledge based
        (Guruharsha et al., 2011)
        Glyp - CG31343
        experimental knowledge based
        (Guruharsha et al., 2011)
        Glyp - CG32473
        experimental knowledge based
        (Guruharsha et al., 2011)
        Glyp - CG5500
        experimental knowledge based
        (Guruharsha et al., 2011)
        Glyp - CG5506
        experimental knowledge based
        (Guruharsha et al., 2011)
        Glyp - Gapdh2
        experimental knowledge based
        (Guruharsha et al., 2011)
        Glyp - Gpdh1
        experimental knowledge based
        (Guruharsha et al., 2011)
        Glyp - Lsp2
        experimental knowledge based
        (Guruharsha et al., 2011)
        Glyp - Mms19
        experimental knowledge based
        (Guruharsha et al., 2011)
        Glyp - Pgam1
        experimental knowledge based
        (Guruharsha et al., 2011)
        Glyp - Pgk
        experimental knowledge based
        (Guruharsha et al., 2011)
        Glyp - Scp1
        experimental knowledge based
        (Guruharsha et al., 2011)
        Glyp - Yp2
        experimental knowledge based
        (Guruharsha et al., 2011)
        Summary of Genetic Interactions
        esyN Network Diagram
        Show/hide secondary interactors 
        (data from AllianceMine provided by esyN)
        esyN Network Key:
        Suppression
        Enhancement
        Other Interaction Browsers
        View in FlyBase Interactions Browser   View in MIST tool (external link)
        Please look at the allele data for full details of the genetic interactions
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        Glyp
        enhanceable
        Tps1
        (Yamada et al., 2019)
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        External Data
        Linkouts
        BioGRID - A database of protein and genetic interactions.
        DroID - A comprehensive database of gene and protein interactions.
        MIST (protein-protein) - An integrated Molecular Interaction Database
        Pathways
        Signaling Pathways (FlyBase)
        Metabolic Pathways
        FlyBase
        GLYCOGEN CATABOLISM
        External Links
        FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel
        KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.
        Reactome Metabolic Pathways - An open-source, open access, manually curated and peer-reviewed metabolic pathway database.
        External Data
        Linkouts
        KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
        Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
        Class of Gene
        Genomic Location and Detailed Mapping Data
        Chromosome (arm)
        2L
        Recombination map
        2-5
        Cytogenetic map
        22C3-22D1
        Sequence location
        FlyBase Computed Cytological Location
        Cytogenetic map
        Evidence for location
        22C3-22D1
        Limits computationally determined from genome sequence between P{lacW}CG31672k09932 and P{PZ}aop03953a&P{EP}aopEP2500
        Experimentally Determined Cytological Location
        Cytogenetic map
        Notes
        References
        22B-22B
        (Cserpan, 1998.6.20, Cserpan, 1998.6.20)
        22B6-22B7
        (determined by in situ hybridisation)
        (Spradling et al., 1999)
        22B6-22B7
        (BDGP Project Members, 1994-1999)
        Experimentally Determined Recombination Data
        Location

        2-5

        (FlyBase, 2016)

        2-4.2

        (Comeron et al., 2012)
        Left of (cM)
        Right of (cM)
        Notes
        Stocks and Reagents
        Stocks (22)
        Genomic Clones (20)
        cDNA Clones (193)
         

        Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

        cDNA clones, fully sequenced
        BDGP DGC clones
        Other clones
        Drosophila Genomics Resource Center cDNA clones

        For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        RNAi and Array Information
        Linkouts
        DRSC - Results frm RNAi screens
        Antibody Information
        Laboratory Generated Antibodies
         
        Commercially Available Antibodies
         
        Cell Line Information
        Publicly Available Cell Lines
         
          Other Stable Cell Lines
           
            Other Comments

            The effects of a high sucrose diet on live weight, total protein, stored lipid and glycogen and crude activities of 12 enzymes involved in energy metabolism are quantified. The activities of many enzymes are reduced by the sucrose treatment.

            (Wang and Clark, 1995)

            GlyP protein has been purified and characterised.

            (Dombradi et al., 1985)
            Relationship to Other Genes
            Source for database merge of

            Source for merge of: GlyP BcDNA:LD24485

            (FlyBase, 1996-)

            Source for merge of: GlyP anon-WO0257455.33

            (FlyBase, 1996-)
            Additional comments

            Source for merge of GlyP BcDNA:LD24485 was sequence comparison ( date:000114 ).

            (FlyBase, 1996-)

            Source for merge of GlyP anon-WO0257455.33 was sequence comparison ( date:051113 ).

            (FlyBase, 1996-)
            Nomenclature History
            Source for database identify of

            Source for identity of: GlyP CG7254

            (Kodira, 1999.11)

            Source for identity of: Glyp GlyP

            (FlyBase, 2017-)
            Nomenclature comments
            Etymology
            Synonyms and Secondary IDs (16)
            Reported As
            Symbol Synonym
            BcDNA:LD24485
            CG7254
            (National Institute of Genetics Fly Stocks, 2022-, Rosa-Ferreira et al., 2015, Cammarato et al., 2011, Ruaud et al., 2011, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Puri et al., 2008)
            DGPH
            (Tick et al., 1999)
            GLP1
            (Staats et al., 2018)
            GP
            (Montooth et al., 2003, Harshman et al., 1999, Clark and Wang, 1997, Wang and Clark, 1995, Clark, 1994, Clark and Wang, 1994, Clark, 1990, Clark et al., 1990)
            Glp1
            (Cserpan, 1998.6.20, Cserpan, 1998.6.20)
            GlyP
            (Avila et al., 2024, Chang et al., 2024, De Groef et al., 2024, McPherson et al., 2024, Dolezal, 2023, Fisher et al., 2023, Gáliková and Klepsatel, 2023, Livelo et al., 2023, Rabah et al., 2023, Deshpande et al., 2022, Deshpande et al., 2022, Eickelberg et al., 2022, Liu et al., 2022, National Institute of Genetics Fly Stocks, 2022-, Chowański et al., 2021, Koyama et al., 2021, Manola et al., 2021, Zhang et al., 2021, Avilés-Pagán et al., 2020, Lee et al., 2020, Miller et al., 2020, Parkhitko et al., 2020, Ramond et al., 2020, Hall et al., 2019, Kurshakova et al., 2019, Manola et al., 2019, Meltzer et al., 2019, Yamada et al., 2019, Aw et al., 2018, Muñoz-Soriano et al., 2018, Post et al., 2018, Mattila and Hietakangas, 2017, Transgenic RNAi Project members, 2017-, Elgart et al., 2016, Gene Disruption Project members, 2016-, Sarov et al., 2016, Gene Disruption Project members, 2015-, Van Bortle et al., 2015, Wójtowicz et al., 2015, Ashwal-Fluss et al., 2014, Mukherjee et al., 2014, Overgaard et al., 2014, Wang et al., 2014, Clark et al., 2013, Colinet et al., 2013, Zirin et al., 2013, Japanese National Institute of Genetics, 2012.5.21, Friedman et al., 2011, Ruaud et al., 2011, Cronin et al., 2009, Kent et al., 2009, Xun et al., 2009, Puri et al., 2008, Dionne et al., 2006, Dorus et al., 2006, Eanes et al., 2006, Sandmann et al., 2006, FlyBase, 1992-)
            Glyp
            (De Groef et al., 2021, Mbodj et al., 2016, Bai et al., 2013)
            PYGM
            (Raghuraman et al., 2020)
            anon-WO0257455.33
            glyP
            (Wang et al., 2016)
            l(2)k07918
            (Beaton, 2000.1.31)
            Name Synonyms
            GLYCOGEN PHOSPHORYLASE
            (Hull et al., 2015)
            Glycogen phosphorylase
            (Rice et al., 2020, Mattila and Hietakangas, 2017, Wang et al., 2014, Cammarato et al., 2011, Xun et al., 2009, Dombradi et al., 1986)
            glycogen phosphorylase
            (Overgaard et al., 2014, Zirin et al., 2013, Musselman et al., 2011, Ruaud et al., 2011, Kent et al., 2009, Eanes et al., 2006)
            glycogen phosphorylase b
            (Dombradi et al., 1985)
            Secondary FlyBase IDs
            • FBgn0027859
            • FBgn0063790
            Datasets (0)
            Study focus (0)
            Experimental Role
            Project
            Project Type
            Title
            Study result (0)
            Result
            Result Type
            Title
            External Crossreferences and Linkouts ( 57 )
            Sequence Crossreferences
            NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
            GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
            GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
            RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
            UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
            UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
            UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
            Other crossreferences
            AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
            BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
            DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
            EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
            FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
            FlyMine - An integrated database for Drosophila genomics
            InterPro - A database of protein families, domains and functional sites
            KEGG Genes - Molecular building blocks of life in the genomic space.
            MARRVEL_MODEL - MARRVEL (model organism gene)
            Linkouts
            BioGRID - A database of protein and genetic interactions.
            Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
            DroID - A comprehensive database of gene and protein interactions.
            DRSC - Results frm RNAi screens
            Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
            FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
            FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
            FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel
            Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
            Flygut - An atlas of the Drosophila adult midgut
            FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.
            iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
            KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.
            KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
            MIST (protein-protein) - An integrated Molecular Interaction Database
            Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
            Reactome Metabolic Pathways - An open-source, open access, manually curated and peer-reviewed metabolic pathway database.
            References (149)