Open Close
General Information
Symbol
Dmel\ex
Species
D. melanogaster
Name
expanded
Annotation Symbol
CG4114
Feature Type
FlyBase ID
FBgn0004583
Gene Model Status
Stock Availability
Gene Summary
expanded (ex) encodes a FERM-domain containing protein that localizes to apical cell-cell junctions, where it promotes Hippo signaling by physically interacting with multiple Hippo pathway components. Through its regulation of Hippo signaling, the product of ex functions as an inhibitor of growth. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)
Key Links
Genomic Location
Cytogenetic map
Sequence location
2L:431,227..448,701 [+]
Recombination map
2-0.7
RefSeq locus
NT_033779 REGION:431227..448701
Sequence
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (25 terms)
Molecular Function (4 terms)
Terms Based on Experimental Evidence (4 terms)
CV Term
Evidence
References
inferred from physical interaction with UniProtKB:Q45VV3
(assigned by UniProt )
inferred from physical interaction with UniProtKB:Q9VZI2
(assigned by UniProt )
inferred from physical interaction with UniProtKB:Q9VFG8
(assigned by UniProt )
inferred from physical interaction with FLYBASE:Mer; FB:FBgn0086384
inferred from physical interaction with FLYBASE:yki; FB:FBgn0034970
Terms Based on Predictions or Assertions (0 terms)
Biological Process (15 terms)
Terms Based on Experimental Evidence (15 terms)
CV Term
Evidence
References
inferred from mutant phenotype
inferred from genetic interaction with FLYBASE:crb; FB:FBgn0259685
inferred from mutant phenotype
inferred from mutant phenotype
inferred from genetic interaction with FLYBASE:Mer; FB:FBgn0086384
inferred from genetic interaction with FLYBASE:Mer; FB:FBgn0086384
inferred from genetic interaction with FLYBASE:wts; FB:FBgn0011739
inferred from mutant phenotype
inferred from genetic interaction with FLYBASE:Mer; FB:FBgn0086384
inferred from mutant phenotype
inferred from genetic interaction with FLYBASE:wts; FB:FBgn0011739
inferred from mutant phenotype
inferred from mutant phenotype
inferred from genetic interaction with FLYBASE:Mer; FB:FBgn0086384
inferred from mutant phenotype
inferred from genetic interaction with FLYBASE:RpL36; FB:FBgn0002579
inferred from genetic interaction with FLYBASE:Mer; FB:FBgn0086384
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
inferred from biological aspect of ancestor with PANTHER:PTN000334995
(assigned by GO_Central )
Cellular Component (6 terms)
Terms Based on Experimental Evidence (5 terms)
CV Term
Evidence
References
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
inferred from biological aspect of ancestor with PANTHER:PTN000334995
(assigned by GO_Central )
located_in cytoskeleton
inferred from electronic annotation with InterPro:IPR000299
(assigned by InterPro )
Gene Group (FlyBase)
Protein Family (UniProt)
-
Summaries
Gene Snapshot
expanded (ex) encodes a FERM-domain containing protein that localizes to apical cell-cell junctions, where it promotes Hippo signaling by physically interacting with multiple Hippo pathway components. Through its regulation of Hippo signaling, the product of ex functions as an inhibitor of growth. [Date last reviewed: 2019-03-07]
Pathway (FlyBase)
Positive Regulators of Hippo Signaling Pathway -
The Hippo signaling pathway is an intracellular kinase cascade in which hpo kinase in complex with sav, phosphorylates wts kinase which, in turn, phosphorylates yki transcriptional co-activator leading to its cytosolic retention. Positive regulators of the pathway, enhance the cytosolic retention of yki, negatively regulating tissue growth (Adapted from FBrf0224870).
Gene Group (FlyBase)
KIBRA-EX-MER COMPLEX -
The KEM complex is an apical protein complex that contains the proteins Kibra, Expanded and Merlin. It positively regulates the Hippo pathway, acting as a scaffolding complex. (Adapted from FBrf0210017).
Protein Function (UniProtKB)
Activates the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (PubMed:8269855, PubMed:20159598, PubMed:27462444, PubMed:26954546). The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. Ex acts synergistically along with Mer and Kibra to regulate the Hippo signaling pathway (PubMed:20159598). Involved in the control of cell proliferation in imaginal disks (PubMed:8269855, PubMed:27462444). May bind to certain proteins of signal transduction pathways by interaction with their SH3 domains (PubMed:20159598). Required for apical localization of Schip1 (PubMed:26954546).
(UniProt, Q07436)
Phenotypic Description (Red Book; Lindsley and Zimm 1992)
brl: braille (M.P. Scott)
Recessive mutation with complete penetrance and variable expressivity. Strongest phenotypes include partial to full transformation of one or both eyes into antennae. Less severe adult phenotypes include excess bristles under the eyes, duplication of the more anterior set of scutellar bristles (macrochaetae), and a spoon-like curvature of the wings. Homozygotes are viable and fertile.
ex: expanded
thumb
ex: expanded
From Stern and Bridges, 1926, Genetics 11: 503-30.
Wings extremely wide and large, sometimes curved and divergent. Effect produced in prepupal wing, probably by influence on cell division (Waddington, 1940, J. Genet. 41: 75-139). Eyes slightly reduced in size and roughish. Body large. RK2.
Summary (Interactive Fly)

Band 4.1 protein with three potential SH3-binding sites - localization to adherens junctions allows Expanded to exert effects on multiple processes involved in disc development, including effects on cell proliferation, cell fate determination, and tissue polarity

Gene Model and Products
Number of Transcripts
2
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\ex for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.43

Gene model reviewed during 5.52

Sequence Ontology: Class of Gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
FBtr0078059
6672
1427
FBtr0329832
6454
1427
Additional Transcript Data and Comments
Reported size (kB)

6.9 (northern blot)

Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
FBpp0077719
153.6
1427
8.45
FBpp0302878
153.6
1427
8.45
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

1427 aa isoforms: ex-PA, ex-PB
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Subunit Structure (UniProtKB)

Forms a complex with Kibra and Mer (PubMed:20159598). Interacts (via RXPPXY motif) with Kibra (via domain WW 1) (PubMed:20159598). Interacts with Mer and Hpo (via SARAH domain) (PubMed:20159598). Interacts with Schip1; the interaction results in recruitment of Schip1 to the apical cell membrane (PubMed:26954546). Interacts with ack and yki (PubMed:27462444).

(UniProt, Q07436)
Post Translational Modification

Phosphorylated by Ack at several tyrosines including Tyr-227, Tyr-423, Tyr-679, Tyr-766 and Tyr-1103.

(UniProt, Q07436)
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\ex using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data

ex transcripts are apically localized in imaginal discs.

Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
western blot
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data

ex protein is localized to the extreme apical cell surface.

ex protein is detected by early third instar in imaginal discs. It is fairly uniform throughout leg discs but is concentrated in the wing pouch relative to other areas of the wing disc.

Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\ex in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
EMBL-EBI Single Cell Expression Atlas
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 34 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 32 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of ex
Transgenic constructs containing regulatory region of ex
Aberrations (Deficiencies and Duplications) ( 12 )
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
Sterility
Allele
Other Phenotypes
Allele
Phenotype manifest in
Allele
interommatidial bristle & eye disc & pupa
Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (2)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
8 of 15
Yes
Yes
5 of 15
No
Yes
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
5 of 15
Yes
Yes
Rattus norvegicus (Norway rat) (2)
4 of 13
Yes
Yes
2 of 13
No
Yes
Xenopus tropicalis (Western clawed frog) (1)
2 of 12
Yes
Yes
Danio rerio (Zebrafish) (2)
6 of 15
Yes
Yes
6 of 15
Yes
Yes
Caenorhabditis elegans (Nematode, roundworm) (3)
9 of 15
Yes
Yes
1 of 15
No
Yes
1 of 15
No
Yes
Arabidopsis thaliana (thale-cress) (0)
No records found.
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (0)
No records found.
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091902MF )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Drosophila simulans
Drosophila sechellia
Drosophila erecta
Drosophila yakuba
Drosophila ananassae
Drosophila pseudoobscura pseudoobscura
Drosophila persimilis
Drosophila willistoni
Drosophila virilis
Drosophila mojavensis
Drosophila grimshawi
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091500GK )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Glossina morsitans
Tsetse fly
Lucilia cuprina
Australian sheep blowfly
Mayetiola destructor
Hessian fly
Aedes aegypti
Yellow fever mosquito
Anopheles darlingi
American malaria mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W02TI )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Danaus plexippus
Monarch butterfly
Heliconius melpomene
Postman butterfly
Apis florea
Little honeybee
Apis mellifera
Western honey bee
Bombus impatiens
Common eastern bumble bee
Bombus terrestris
Buff-tailed bumblebee
Linepithema humile
Argentine ant
Megachile rotundata
Alfalfa leafcutting bee
Nasonia vitripennis
Parasitic wasp
Dendroctonus ponderosae
Mountain pine beetle
Dendroctonus ponderosae
Mountain pine beetle
Tribolium castaneum
Red flour beetle
Pediculus humanus
Human body louse
Rhodnius prolixus
Kissing bug
Cimex lectularius
Bed bug
Acyrthosiphon pisum
Pea aphid
Zootermopsis nevadensis
Nevada dampwood termite
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X04VR )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Daphnia pulex
Water flea
Daphnia pulex
Water flea
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G07H1 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (0)
No records found.
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Model Summary Ribbon
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 2 )
Allele
Disease
Evidence
References
Potential Models Based on Orthology ( 0 )
Human Ortholog
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 4 )
Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
Functional Complementation Data
Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
Interactions
Summary of Physical Interactions
esyN Network Diagram
Show neighbor-neighbor interactions:
Select Layout:
Legend:
Protein
RNA
Selected Interactor(s)
Interactions Browser

Please see the Physical Interaction reports below for full details
RNA-RNA
Physical Interaction
Assay
References
protein-protein
Physical Interaction
Assay
References
Summary of Genetic Interactions
esyN Network Diagram
esyN Network Key:
Suppression
Enhancement

Please look at the allele data for full details of the genetic interactions
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
enhanceable
External Data
Subunit Structure (UniProtKB)
Forms a complex with Kibra and Mer (PubMed:20159598). Interacts (via RXPPXY motif) with Kibra (via domain WW 1) (PubMed:20159598). Interacts with Mer and Hpo (via SARAH domain) (PubMed:20159598). Interacts with Schip1; the interaction results in recruitment of Schip1 to the apical cell membrane (PubMed:26954546). Interacts with ack and yki (PubMed:27462444).
(UniProt, Q07436 )
Linkouts
BioGRID - A database of protein and genetic interactions.
DroID - A comprehensive database of gene and protein interactions.
MIST (genetic) - An integrated Molecular Interaction Database
MIST (protein-protein) - An integrated Molecular Interaction Database
Pathways
Signaling Pathways (FlyBase)
Positive Regulators of Hippo Signaling Pathway -
The Hippo signaling pathway is an intracellular kinase cascade in which hpo kinase in complex with sav, phosphorylates wts kinase which, in turn, phosphorylates yki transcriptional co-activator leading to its cytosolic retention. Positive regulators of the pathway, enhance the cytosolic retention of yki, negatively regulating tissue growth (Adapted from FBrf0224870).
Metabolic Pathways
External Data
Linkouts
KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
Genomic Location and Detailed Mapping Data
Chromosome (arm)
2L
Recombination map
2-0.7
Cytogenetic map
Sequence location
2L:431,227..448,701 [+]
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
21C2-21C2
Limits computationally determined from genome sequence between P{lacW}l(2)k09610k09610&P{lacW}Sk09538a and P{PZ}l(2)1068510685&P{lacW}Tango14k00619
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
21C4-21C5
(determined by in situ hybridisation)
21C-21C
(determined by in situ hybridisation)
21C1-21C4
(determined by in situ hybridisation)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Stocks and Reagents
Stocks (27)
Genomic Clones (16)
 

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (19)
 

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced
BDGP DGC clones
Other clones
    Drosophila Genomics Resource Center cDNA clones

    For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

    cDNA Clones, End Sequenced (ESTs)
    BDGP DGC clones
    RNAi and Array Information
    Linkouts
    DRSC - Results frm RNAi screens
    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
    Antibody Information
    Laboratory Generated Antibodies
    Commercially Available Antibodies
     
    Other Information
    Relationship to Other Genes
    Source for database identify of

    Source for identity of: ex CG4114

    Source for database merge of

    Source for merge of: ex l(2)01270

    Source for merge of: ex l(2)k12913

    Source for merge of: ex brl

    Additional comments
    Other Comments

    dsRNA made from templates generated with primers directed against this gene is tested in an S2 cell phosphorylation experiment to assess teh hpo signal transduction pathway.

    The actions of ex are epistatic to ft.

    dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.

    ex has a common role in all disc tissues and can negatively regulate tissue growth, induce apoptosis, and perturb planar polarity.

    Mer and ex function cooperatively in regulating cell proliferation and differentiation in developing epithelial cells.

    Identification: Enhancer trap expression pattern survey for loci expressed in the ring gland.

    Clonal analysis reveals that ex functions in the apical cell domain to regulate the growth rate of imaginal discs.

    Variation of a microsatellite within the ex locus has been studied in North American populations of D.melanogaster.

    Mutants display hyperplastic phenotype, with imaginal disc overgrowth.

    The ex gene is necessary for proper growth control of imaginal discs.

    Presumed additional alleles obtained by mobilization of P-element. All are recessive lethals that die during early larval stages.

    Origin and Etymology
    Discoverer
    Etymology
    Identification
    External Crossreferences and Linkouts ( 55 )
    Sequence Crossreferences
    NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
    GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
    GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
    RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
    UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
    UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
    Other crossreferences
    Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
    EMBL-EBI Single Cell Expression Atlas
    Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
    Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
    Flygut - An atlas of the Drosophila adult midgut
    Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
    iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
    KEGG Genes - Molecular building blocks of life in the genomic space.
    MARRVEL_MODEL
    modMine - A data warehouse for the modENCODE project
    Linkouts
    ApoDroso - Functional genomic database for photoreceptor development, survival and function
    BioGRID - A database of protein and genetic interactions.
    DroID - A comprehensive database of gene and protein interactions.
    DRSC - Results frm RNAi screens
    FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
    FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
    FlyMine - An integrated database for Drosophila genomics
    Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
    KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
    MIST (genetic) - An integrated Molecular Interaction Database
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
    Synonyms and Secondary IDs (12)
    Reported As
    Symbol Synonym
    brl
    ex
    (Ahmad et al., 2021, Badmos et al., 2021, Ferguson et al., 2021, Srivastava et al., 2021, Tokamov et al., 2021, Xu et al., 2021, Yang and Choi, 2021, Baker, 2020, Deng et al., 2020, Earl et al., 2020, Guo et al., 2020, Mugat et al., 2020, Sun et al., 2020, Wang and Spradling, 2020, Yu et al., 2020, Alégot et al., 2019, Chang et al., 2019, Li et al., 2019, Liu et al., 2019, Ma et al., 2019, Misra and Irvine, 2019, Nan et al., 2019, Sarpal et al., 2019, Snigdha et al., 2019, Wang and Baker, 2019, Wang et al., 2019, Wong et al., 2019, Xu et al., 2019, Yee et al., 2019, Zhang et al., 2019, Albert et al., 2018, Cho et al., 2018, Fletcher et al., 2018, Katsukawa et al., 2018, Lee et al., 2018, Tsai et al., 2018, Wang and Baker, 2018, Wang et al., 2018, Yu and Pan, 2018, Hevia et al., 2017, Martín et al., 2017, Pascual et al., 2017, Shu and Deng, 2017, Su et al., 2017, Yamamoto et al., 2017, Zhang et al., 2017, Zheng et al., 2017, Boone et al., 2016, Chung et al., 2016, Deng et al., 2016, Gene Disruption Project members, 2016-, Huang et al., 2016, Kockel et al., 2016, Kwan et al., 2016, Misra and Irvine, 2016, Shih et al., 2016, Suijkerbuijk et al., 2016, Bosch et al., 2015, Dent et al., 2015, Doggett et al., 2015, Dong et al., 2015, Enomoto et al., 2015, Fletcher et al., 2015, Jia et al., 2015, Keder et al., 2015, Kwon et al., 2015, Li et al., 2015, Meng et al., 2015, Parker and Struhl, 2015, Su, 2015, Zaessinger et al., 2015, Zhang et al., 2015, Zhang et al., 2015, Zhu et al., 2015, Ashwal-Fluss et al., 2014, Bossuyt et al., 2014, Huang and Kalderon, 2014, Huang et al., 2014, Qing et al., 2014, Rauskolb et al., 2014, Robbins et al., 2014, Tipping and Perrimon, 2014, Christiansen et al., 2013, Degoutin et al., 2013, Deng et al., 2013, Huang et al., 2013, Ilanges et al., 2013, Jukam et al., 2013, Khan et al., 2013, Koontz et al., 2013, Kwon et al., 2013, Losick et al., 2013, Lucas et al., 2013, Marcinkevicius and Zallen, 2013, McKay and Lieb, 2013, Oh et al., 2013, Ohtani et al., 2013, Perea et al., 2013, Sidor et al., 2013, Webber et al., 2013, Yu et al., 2013, Chen and Verheyen, 2012, Chen et al., 2012, Fletcher et al., 2012, Hafezi et al., 2012, Herranz et al., 2012, Matakatsu and Blair, 2012, Zhang et al., 2012, Bao et al., 2011, Djiane et al., 2011, Fernández et al., 2011, Friedman et al., 2011, Gilbert et al., 2011, Grusche et al., 2011, Jukam and Desplan, 2011, Laprise, 2011, Poon et al., 2011, Rauskolb et al., 2011, Reddy and Irvine, 2011, Richter et al., 2011, Slattery et al., 2011, Sun et al., 2011, Yan et al., 2011, Zhang et al., 2011, Baumgartner et al., 2010, Baumgartner et al., 2010, Chen et al., 2010, Genevet et al., 2010, Genevet et al., 2010, Grzeschik et al., 2010, Kühnlein, 2010, Ling et al., 2010, Milton et al., 2010, Morrison and Halder, 2010, Neto-Silva et al., 2010, Reddy et al., 2010, Ribeiro et al., 2010, Robinson et al., 2010, Shaw et al., 2010, Terriente-Félix et al., 2010, Yu et al., 2010, Yu et al., 2010, Zecca and Struhl, 2010, Ziosi et al., 2010, Classen et al., 2009, Genevet et al., 2009, Ida et al., 2009, Oh and Irvine, 2009, Sopko et al., 2009, Zhang et al., 2009, Lee et al., 2008, Oh and Irvine, 2008, Rogulja et al., 2008, Sun et al., 2008, Willecke et al., 2008, Yu et al., 2008, Zhang et al., 2008, Zhang et al., 2008, Zhao et al., 2008, Acevedo et al., 2007, Feng and Irvine, 2007, Feng et al., 2007, Meignin et al., 2007, Pellock et al., 2007, Polesello and Tapon, 2007, Tyler and Baker, 2007, Tyler et al., 2007, Zhao et al., 2007, Bennett and Harvey, 2006, Cho et al., 2006, Hamaratoglu et al., 2006, Hamaratoglu et al., 2006, Maitra et al., 2006, Maitra et al., 2006, Molnar et al., 2006, Polesello et al., 2006, Silva, 2006, Willecke et al., 2006, McCartney et al., 2000)
    Name Synonyms
    braille
    Secondary FlyBase IDs
    • FBgn0000220
    • FBgn0000610
    • FBgn0002118
    • FBgn0010479
    • FBgn0021897
    Datasets (1)
    Study focus (1)
    Experimental Role
    Project
    Project Type
    Title
    • bait_protein
    Interaction map generated by purification of Hippo pathway factors, with identification of copurifying proteins by mass spectrometry.
    References (413)