I71-7, Gene VII, gp150
Please see the JBrowse view of Dmel\Eig71Ee for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Apparent introns not annotated: probable artifacts due to repetitive sequence.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.45
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Eig71Ee using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\Eig71Ee in JBrowse3-43
3-37.4
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
The br complex (BR-C) early gene encoded by the Z1 isoform (rbp) directly activates late gene transcription (genes from the 71E salivary glands late puff) by interacting with late gene cis-acting regulatory elements and this interaction is responsible for the temporal linkage of early and late ecdysone-induced gene expression.
71E region contains a cluster of 11 developmentally regulated genes. The transcriptional structure, gene organisation and expression pattern are studied.
Gene expression is unaffected in Eip74EFneo24 mutants but transcripts are barely detectable in Eip74EFDL-1 mutants.
Ecdysteroid-regulated gene.
Eig71Ea, Eig71Eb, Eig71Ec, Eig71Ed, Eig71Ee and Eig71Ef have very reduced levels of transcript accumulation in hemizygous brrbp-1 larvae and pupae compared to wild type.