Gene model reviewed during 5.53
There is only one protein coding transcript and one polypeptide associated with this gene
Component of the Cdk8 module of the Mediator complex, composed of CycC, Cdk8, kto and skd.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CycC using the Feature Mapper tool.
CycC expression correlates with periods of maximal cell division throughout Drosophila development. It is expressed maximally in ovaries and in early embryos and at low levels in larvae, pupae, and adults. Expression is uniform throughout the embryo.
Maternal CycC transripts are detected in the embryo. They are concentrated in the islands of yolk-free cytoplasm associated with nuclei, and relocate to the cortical region of the syncytial egg upon nuclear migration to the surface. The signal persists through germband extension but no localized accumulation is seen.
GBrowse - Visual display of RNA-Seq signalsView Dmel\CycC in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: CycC CG7281
dsRNA has been made from templates generated with primers directed against this gene.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Overexpression in the eye-antenna imaginal disc has no effect on the morphology of eyes of the resulting adults.
CycC is a single copy gene. CycC expression in yeast cells lacking cyclin expression can rescue the mutant phenotype.