Dfur2, Dfurin2, furin
Gene model reviewed during 5.50
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.55
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Fur2 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Fur2 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
The genetic organisation, expression during embryogenesis and cleavage specificity of Fur2 gene product have been characterised.
Fur2 encodes an endoproteolytic enzyme. Cos cell transfection experiments with von Willebrand factor reveal a specificity for action on paired basic amino acid residues.
Isolated from a genomic library using a human furin cDNA as a probe, under reduced stringency conditions.