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Gene Dmel\GluRIIA

General Information
Symbol	Dmel\GluRIIA	Species	D. melanogaster
Name	Glutamate receptor IIA	Annotation symbol	CG6992
Feature type	protein_coding_gene	FlyBase ID	FBgn0004620
Gene Model Status	Current	Stock availability	3 publicly available
Also Known As	dglurIIA, DGluR-IIA, DGluR-II, GluR, GluRII-A, GluRII, DgluRII
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	25E6-25E6	Sequence location	2L:5,555,074..5,558,994 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Glutamate receptor IIA is referred to in FlyBase by the symbol Dmel\GluRIIA (CG6992, FBgn0004620). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: glutamate receptor activity. There is experimental evidence that it is involved in the biological process: synaptic transmission; regulation of neurotransmitter secretion; regulation of synaptic activity. 22 alleles are reported. The phenotypes of these alleles are annotated with: t-bar; bouton; neuromuscular junction; embryonic/larval neuromuscular junction; type I bouton; synapse; synaptic vesicle. It has one annotated transcript and one annotated polypeptide. Protein features are: Extracellular ligand-binding receptor; Glutamate receptor, L-glutamate/glycine-binding; Ionotropic glutamate receptor; NMDA receptor. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult heart, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1630710_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of GluRIIA. Gene sequence location is 2L:5555074..5558994.
External Summaries
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	References Kuromi et al., 2010, Europ. J. Neurosci. 32(3): 335--346 Sequence features BKN24573 HFA03334
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 25E6-25E6   Limits computationally determined from genome sequence between P{lacW}Hel25Ek11511 and P{lacW}l(2)k06502k06502
Experimentally Determined Cytological Location
Cytogenetic map Notes References 25F-25F   (determined by in situ hybridisation)   (Petersen et al., 1997) 25F-25F   (determined by in situ hybridisation)   (Schuster et al., 1991)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\GluRIIA for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	5' UTR of this gene overlaps the 3' UTR of upstream gene CG14017.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) GluRIIA-RI FBtr0079106  NM_078760   3251   907
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein GluRIIA-PI   FBpp0078739   104.4   907   6.06     NP_523484   AAF52268
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ionotropic glutamate receptor (IPR001320) NMDA receptor (IPR001508) Extracellular ligand-binding receptor (IPR001828) Glutamate receptor, L-glutamate/glycine-binding (IPR019594)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014134 AAF52268   AY113288   BI229985   BT010006 AAQ22475   CO178804   CS133219   EC051159   EC056174   GH750885   GH751188   GH752273   GH773029   GH776398   GH776687   GH778392   GH781646   GH795158   GH799030   GH801444   GH803288   GH809289   GH811003   GH811285   GH811874   GH812381   GH813267   GH817844   GH823757   GH826391   GH826410   GH829554   GH830649   GH840619   GH856615   GH859219   GH859583   GH874549   GH875356   GH887397   GH892073   GH892084   GH907112   GH910630   GH915821   GH916851   GH916925   GH928326   GH929505   GH931276   GH939242   GH939709   M73271 AAA28574
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q24351 Q9VMP4
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
immunolocalization Stage Tissue/Position (including subcellular localization) Reference embryonic stage 17   embryonic/larval neuromuscular junction   (Saitoe et al., 2001) third instar larval stage   somatic muscle   • neuromuscular junction (Marrus et al., 2004) somatic muscle   • type Ib terminal button (Marrus et al., 2004) somatic muscle   • type II terminal button (Marrus et al., 2004)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0004620    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0004620 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0004620 expression level Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    67 embryo 04-06hr    8 embryo 06-08hr    15 embryo 08-10hr    28 embryo 10-12hr    142 embryo 12-14hr    464 embryo 14-16hr    955 embryo 16-18hr    955 embryo 18-20hr    1232 embryo 20-22hr    1186 embryo 22-24hr    1326 larva L1    568 larva L2    431 larva L3 12hr old    365 larva L3 puffstage 1-2    225 larva L3 puffstage 3-6    421 larva L3 puffstage 7-9    570 white prepupae new    451 white prepupae 12hr    270 white prepupae 24hr    165 pupae 2d postWPP    202 pupae 3d postWPP    270 pupae 4d postWPP    685 adult male 01day    451 adult male 05day    332 adult male 30day    352 adult female 01day    312 adult female 05day    84 adult female 30day    93 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    67 embryo 04-06hr    8 embryo 06-08hr    15 embryo 08-10hr    28 embryo 10-12hr  (142) embryo 12-14hr  (464) embryo 14-16hr  (955) embryo 16-18hr  (955) embryo 18-20hr  (1232) embryo 20-22hr  (1186) embryo 22-24hr  (1326) larva L1  (568) larva L2  (431) larva L3 12hr old  (365) larva L3 puffstage 1-2  (225) larva L3 puffstage 3-6  (421) larva L3 puffstage 7-9  (570) white prepupae new  (451) white prepupae 12hr  (270) white prepupae 24hr  (165) pupae 2d postWPP  (202) pupae 3d postWPP  (270) pupae 4d postWPP  (685) adult male 01day  (451) adult male 05day  (332) adult male 30day  (352) adult female 01day  (312) adult female 05day    84 adult female 30day    93 Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    67 embryo 04-06hr    8 embryo 06-08hr    15 embryo 08-10hr    28 embryo 10-12hr    142 embryo 12-14hr    464 embryo 14-16hr    955 embryo 16-18hr    955 embryo 18-20hr    1232 embryo 20-22hr    1186 embryo 22-24hr    1326 larva L1    568 larva L2    431 larva L3 12hr old    365 larva L3 puffstage 1-2    225 larva L3 puffstage 3-6    421 larva L3 puffstage 7-9    570 white prepupae new    451 white prepupae 12hr    270 white prepupae 24hr    165 pupae 2d postWPP    202 pupae 3d postWPP    270 pupae 4d postWPP    685 adult male 01day    451 adult male 05day    332 adult male 30day    352 adult female 01day    312 adult female 05day    84 adult female 30day    93 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    67 embryo 04-06hr    8 embryo 06-08hr    15 embryo 08-10hr    28 embryo 10-12hr    142 embryo 12-14hr    464 embryo 14-16hr    955 embryo 16-18hr    955 embryo 18-20hr    1232 embryo 20-22hr    1186 embryo 22-24hr    1326 larva L1    568 larva L2    431 larva L3 12hr old    365 larva L3 puffstage 1-2    225 larva L3 puffstage 3-6    421 larva L3 puffstage 7-9    570 white prepupae new    451 white prepupae 12hr    270 white prepupae 24hr    165 pupae 2d postWPP    202 pupae 3d postWPP    270 pupae 4d postWPP    685 adult male 01day    451 adult male 05day    332 adult male 30day    352 adult female 01day    312 adult female 05day    84 adult female 30day    93 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    67 embryo 04-06hr    8 embryo 06-08hr    15 embryo 08-10hr    28 embryo 10-12hr    142 embryo 12-14hr    464 embryo 14-16hr    955 embryo 16-18hr    955 embryo 18-20hr    1232 embryo 20-22hr    1186 embryo 22-24hr    1326 larva L1    568 larva L2    431 larva L3 12hr old    365 larva L3 puffstage 1-2    225 larva L3 puffstage 3-6    421 larva L3 puffstage 7-9    570 white prepupae new    451 white prepupae 12hr    270 white prepupae 24hr    165 pupae 2d postWPP    202 pupae 3d postWPP    270 pupae 4d postWPP    685 adult male 01day    451 adult male 05day    332 adult male 30day    352 adult female 01day    312 adult female 05day    84 adult female 30day    93 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0004620 expression level Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    67 embryo 04-06hr    8 embryo 06-08hr    15 embryo 08-10hr    28 embryo 10-12hr    142 embryo 12-14hr    464 embryo 14-16hr    955 embryo 16-18hr    955 embryo 18-20hr    1232 embryo 20-22hr    1186 embryo 22-24hr    1326 larva L1    568 larva L2    431 larva L3 12hr old    365 larva L3 puffstage 1-2    225 larva L3 puffstage 3-6    421 larva L3 puffstage 7-9    570 white prepupae new    451 white prepupae 12hr    270 white prepupae 24hr    165 pupae 2d postWPP    202 pupae 3d postWPP    270 pupae 4d postWPP    685 adult male 01day    451 adult male 05day    332 adult male 30day    352 adult female 01day    312 adult female 05day    84 adult female 30day    93 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    67 embryo 04-06hr    8 embryo 06-08hr    15 embryo 08-10hr    28 embryo 10-12hr  142 embryo 12-14hr  (464) embryo 14-16hr  (955) embryo 16-18hr  (955) embryo 18-20hr  (1232) embryo 20-22hr  (1186) embryo 22-24hr  (1326) larva L1  (568) larva L2  (431) larva L3 12hr old  (365) larva L3 puffstage 1-2  (225) larva L3 puffstage 3-6  (421) larva L3 puffstage 7-9  (570) white prepupae new  (451) white prepupae 12hr  (270) white prepupae 24hr  (165) pupae 2d postWPP  (202) pupae 3d postWPP  (270) pupae 4d postWPP  (685) adult male 01day  (451) adult male 05day  (332) adult male 30day  (352) adult female 01day  (312) adult female 05day    84 adult female 30day    93 Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    67 embryo 04-06hr    8 embryo 06-08hr    15 embryo 08-10hr    28 embryo 10-12hr    142 embryo 12-14hr    464 embryo 14-16hr    955 embryo 16-18hr    955 embryo 18-20hr    1232 embryo 20-22hr    1186 embryo 22-24hr    1326 larva L1    568 larva L2    431 larva L3 12hr old    365 larva L3 puffstage 1-2    225 larva L3 puffstage 3-6    421 larva L3 puffstage 7-9    570 white prepupae new    451 white prepupae 12hr    270 white prepupae 24hr    165 pupae 2d postWPP    202 pupae 3d postWPP    270 pupae 4d postWPP    685 adult male 01day    451 adult male 05day    332 adult male 30day    352 adult female 01day    312 adult female 05day    84 adult female 30day    93 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    67 embryo 04-06hr    8 embryo 06-08hr    15 embryo 08-10hr    28 embryo 10-12hr    142 embryo 12-14hr    464 embryo 14-16hr    955 embryo 16-18hr    955 embryo 18-20hr    1232 embryo 20-22hr    1186 embryo 22-24hr    1326 larva L1    568 larva L2    431 larva L3 12hr old    365 larva L3 puffstage 1-2    225 larva L3 puffstage 3-6    421 larva L3 puffstage 7-9    570 white prepupae new    451 white prepupae 12hr    270 white prepupae 24hr    165 pupae 2d postWPP    202 pupae 3d postWPP    270 pupae 4d postWPP    685 adult male 01day    451 adult male 05day    332 adult male 30day    352 adult female 01day    312 adult female 05day    84 adult female 30day    93 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    67 embryo 04-06hr    8 embryo 06-08hr    15 embryo 08-10hr    28 embryo 10-12hr    142 embryo 12-14hr    464 embryo 14-16hr    955 embryo 16-18hr    955 embryo 18-20hr    1232 embryo 20-22hr    1186 embryo 22-24hr    1326 larva L1    568 larva L2    431 larva L3 12hr old    365 larva L3 puffstage 1-2    225 larva L3 puffstage 3-6    421 larva L3 puffstage 7-9    570 white prepupae new    451 white prepupae 12hr    270 white prepupae 24hr    165 pupae 2d postWPP    202 pupae 3d postWPP    270 pupae 4d postWPP    685 adult male 01day    451 adult male 05day    332 adult male 30day    352 adult female 01day    312 adult female 05day    84 adult female 30day    93 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0004620    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0004620 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult heart, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0004620 expression level Tissue   Expression Level Larval Central Nervous System    4.075 Larval Midgut    21.6 Larval Hindgut    45.1 Larval Malpighian Tubules    56.5 Larval Fat Body    5.9 Larval Salivary Gland    4.2 Larval Trachea    8.3 Larval Carcass    132.3 Adult Head    19.4 Adult Eye no informative data Adult Brain    37.8 Adult Thoracic-Abdominal Ganglion    27.2 Adult Crop    42.2 Adult Midgut    20 Adult Hindgut    67.4 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland    9.6 Adult Heart    135.575 Adult VirginFemale Spermatheca    16.9 Adult InseminatedFemale Spermatheca    25.7 Adult Ovary    3.2 Adult Testis    11.5 Adult Male Accessory Gland    28.3 Adult Carcass    31.4 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    4.075 Larval Midgut    21.6 Larval Hindgut    45.1 Larval Malpighian Tubules    56.5 Larval Fat Body    5.9 Larval Salivary Gland    4.2 Larval Trachea    8.3 Larval Carcass    132.3 Adult Head    19.4 Adult Eye no informative data Adult Brain    37.8 Adult Thoracic-Abdominal Ganglion    27.2 Adult Crop    42.2 Adult Midgut    20 Adult Hindgut    67.4 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland    9.6 Adult Heart    135.575 Adult VirginFemale Spermatheca    16.9 Adult InseminatedFemale Spermatheca    25.7 Adult Ovary    3.2 Adult Testis    11.5 Adult Male Accessory Gland    28.3 Adult Carcass    31.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    4.075 Larval Midgut    21.6 Larval Hindgut    45.1 Larval Malpighian Tubules    56.5 Larval Fat Body    5.9 Larval Salivary Gland    4.2 Larval Trachea    8.3 Larval Carcass    132.3 Adult Head    19.4 Adult Eye no informative data Adult Brain    37.8 Adult Thoracic-Abdominal Ganglion    27.2 Adult Crop    42.2 Adult Midgut    20 Adult Hindgut    67.4 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland    9.6 Adult Heart    135.575 Adult VirginFemale Spermatheca    16.9 Adult InseminatedFemale Spermatheca    25.7 Adult Ovary    3.2 Adult Testis    11.5 Adult Male Accessory Gland    28.3 Adult Carcass    31.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    4.075 Larval Midgut    21.6 Larval Hindgut    45.1 Larval Malpighian Tubules    56.5 Larval Fat Body    5.9 Larval Salivary Gland    4.2 Larval Trachea    8.3 Larval Carcass    132.3 Adult Head    19.4 Adult Eye no informative data Adult Brain    37.8 Adult Thoracic-Abdominal Ganglion    27.2 Adult Crop    42.2 Adult Midgut    20 Adult Hindgut    67.4 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland    9.6 Adult Heart    135.575 Adult VirginFemale Spermatheca    16.9 Adult InseminatedFemale Spermatheca    25.7 Adult Ovary    3.2 Adult Testis    11.5 Adult Male Accessory Gland    28.3 Adult Carcass    31.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0004620 expression level Tissue   Expression Level Larval Central Nervous System    4.075 Larval Midgut    21.6 Larval Hindgut    45.1 Larval Malpighian Tubules    56.5 Larval Fat Body    5.9 Larval Salivary Gland    4.2 Larval Trachea    8.3 Larval Carcass    132.3 Adult Head    19.4 Adult Eye no informative data Adult Brain    37.8 Adult Thoracic-Abdominal Ganglion    27.2 Adult Crop    42.2 Adult Midgut    20 Adult Hindgut    67.4 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland    9.6 Adult Heart    135.575 Adult VirginFemale Spermatheca    16.9 Adult InseminatedFemale Spermatheca    25.7 Adult Ovary    3.2 Adult Testis    11.5 Adult Male Accessory Gland    28.3 Adult Carcass    31.4 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    4.075 Larval Midgut    21.6 Larval Hindgut    45.1 Larval Malpighian Tubules    56.5 Larval Fat Body    5.9 Larval Salivary Gland    4.2 Larval Trachea    8.3 Larval Carcass    132.3 Adult Head    19.4 Adult Eye no informative data Adult Brain    37.8 Adult Thoracic-Abdominal Ganglion    27.2 Adult Crop    42.2 Adult Midgut    20 Adult Hindgut    67.4 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland    9.6 Adult Heart    135.575 Adult VirginFemale Spermatheca    16.9 Adult InseminatedFemale Spermatheca    25.7 Adult Ovary    3.2 Adult Testis    11.5 Adult Male Accessory Gland    28.3 Adult Carcass    31.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    4.075 Larval Midgut    21.6 Larval Hindgut    45.1 Larval Malpighian Tubules    56.5 Larval Fat Body    5.9 Larval Salivary Gland    4.2 Larval Trachea    8.3 Larval Carcass    132.3 Adult Head    19.4 Adult Eye no informative data Adult Brain    37.8 Adult Thoracic-Abdominal Ganglion    27.2 Adult Crop    42.2 Adult Midgut    20 Adult Hindgut    67.4 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland    9.6 Adult Heart    135.575 Adult VirginFemale Spermatheca    16.9 Adult InseminatedFemale Spermatheca    25.7 Adult Ovary    3.2 Adult Testis    11.5 Adult Male Accessory Gland    28.3 Adult Carcass    31.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    4.075 Larval Midgut    21.6 Larval Hindgut    45.1 Larval Malpighian Tubules    56.5 Larval Fat Body    5.9 Larval Salivary Gland    4.2 Larval Trachea    8.3 Larval Carcass    132.3 Adult Head    19.4 Adult Eye no informative data Adult Brain    37.8 Adult Thoracic-Abdominal Ganglion    27.2 Adult Crop    42.2 Adult Midgut    20 Adult Hindgut    67.4 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland    9.6 Adult Heart    135.575 Adult VirginFemale Spermatheca    16.9 Adult InseminatedFemale Spermatheca    25.7 Adult Ovary    3.2 Adult Testis    11.5 Adult Male Accessory Gland    28.3 Adult Carcass    31.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye no informative data Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    19.4   NA  Eye    no informative data   NA  Brain    37.8   4.075  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    27.2   NA  Crop    42.2   21.6  Midgut    20   45.1  Hindgut    67.4   56.5  Malpighian Tubules    no informative data   5.9  Fat Body    no informative data   4.2  Salivary Gland    9.6   NA  Heart    135.575   8.3  Trachea    NA   NA  VirginFemale Spermatheca    16.9   NA  InseminatedFemale Spermatheca    25.7   NA  Ovary    3.2   NA  Testis    11.5   NA  Male Accessory Gland    28.3   132.3  Carcass    31.4 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_18
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0004620 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6992-RI
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4how-24B GluRIIAM614R.Scer\UAS.T:Hsap\MYC viable GluRIIAAD9 GluRIIASP16 Other Phenotypes Allele locomotor behavior defective | heat sensitive (with Df(2L)cl-h4) GluRIIAAD9 neuroanatomy defective GluRIIAAD9 GluRIIASP16 neuroanatomy defective, with Scer\GAL4how-24B GluRIIAScer\UAS.cPa neuroanatomy defective, with Scer\GAL4Mhc.PW GluRIIAScer\UAS.cPa neuroanatomy defective (with Df(2L)cl-h4) GluRIIAAD9 neurophysiology defective GluRIIAAD9 GluRIIASP16 GluRIIAunspecified neurophysiology defective, with Scer\GAL4C142 GluRIIAM614R.Scer\UAS.T:Hsap\MYC neurophysiology defective, with Scer\GAL4Mhc.PW GluRIIAScer\UAS.cPa neurophysiology defective (with Df(2L)cl-h4) GluRIIAAD9 GluRIIASP16 neurophysiology defective | recessive | third instar larval stage GluRIIASP16 wild-type GluRIIA+tg GluRIIAMhc.PP Phenotype manifest in Allele bouton GluRIIAAD9 GluRIIASP16 embryonic/larval neuromuscular junction GluRIIASP16 embryonic/larval neuromuscular junction, with Scer\GAL4Mhc.PW GluRIIAScer\UAS.cPa embryonic/larval neuromuscular junction | heat sensitive (with Df(2L)cl-h4) GluRIIAAD9 neuromuscular junction GluRIIASP16 neuromuscular junction | larval stage, with Scer\GAL4how-24B GluRIIAScer\UAS.cPa neuromuscular junction | larval stage, with Scer\GAL4Mhc.PW GluRIIAScer\UAS.cPa synapse GluRIIAAD9 GluRIIASP16 synapse, with Scer\GAL4Mhc.PW GluRIIAScer\UAS.cPa synaptic vesicle GluRIIAAD9 GluRIIASP16 synaptic vesicle, with Scer\GAL4how-24B GluRIIAScer\UAS.cPa t-bar (with Df(2L)cl-h4) GluRIIAAD9 GluRIIASP16 type I bouton (with Df(2L)cl-h4) GluRIIAAD9
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of GluRIIA Class Mutagen Stocks Known lesion GluRIIAMB01746 1 -- GluRIIAAD9 loss of function allele P-element activity 0 Yes GluRIIAg9 0 -- GluRIIASP16 loss of function allele P-element activity 0 Yes GluRIIAunspecified 0 --
Alleles Carried on Transgenic Constructs ( 17 )
For All Alleles Carried on Transgenic Constructs Show
Allele of GluRIIA Class Mutagen Stocks Known lesion GluRIIAJF02647 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes GluRIIAKK105437 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes GluRIIA+t.cSa in vitro construct - genomic fragment 0 -- GluRIIA+tg in vitro construct - genomic fragment 0 Yes GluRIIA+tRa in vitro construct - genomic fragment 0 Yes GluRIIAGD916 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes GluRIIAGluRIIB.CTD.T:Avic\GFP-EGFP in vitro construct - genomic fragment in vitro construct - coding region fusion 0 Yes GluRIIAhypo.Scer\UAS in vitro construct - regulatory fusion 0 Yes GluRIIAM614R.Scer\UAS.T:Hsap\MYC in vitro construct - regulatory fusion in vitro construct - coding region fusion in vitro construct - amino acid replacement in vitro construct - site directed mutagenesis 0 Yes GluRIIAMhc.PP in vitro construct - regulatory fusion 0 Yes GluRIIAMhc.T:Hsap\MYC in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes GluRIIAScer\UAS.cPa in vitro construct - regulatory fusion 0 Yes GluRIIAScer\UAS.T:Avic\GFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes GluRIIAScer\UAS.T:Hsap\MYC in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes GluRIIAT:Avic\GFP-EGFP in vitro construct - coding region fusion 0 Yes GluRIIAT:Avic\GFP-PA in vitro construct - coding region fusion 0 Yes GluRIIAT:Disc\RFP-mRFP in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)cl-h4 (Sigrist et al., 2002) Df(2L)Exel6256 (Ryder, 2004.4.26) Df(2L)Exel7023 (Ryder, 2004.4.26) Df(2L)Exel8016 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD916} NA P{KK105437} NA P{TRiP.JF02647} NA P{UAS-GluRIIA.hypo} NA P{UAS-GluRIIA.M614R} NA P{UAS-GluRIIA.myc} NA P{UAS-GluRIIA.P} NA P{UAS-GluRIIA-GFP} NA characterization construct P{GluRIIA.CTDGluRIIB-GFP} NA P{GluRIIA+g} NA P{GluRIIA-mRFP} NA P{Mhc.GluRIIA.Myc} NA P{Mhc.GluRIIA.P} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{lacW}60 No P{lacW}72 No P{lacW}176 No P{lacW}228 No insertion of enhancer trap binary system Mi{ET1}GluRIIAMB01746 No
Gene Ontology: Function, Process & Cellular Component ( 12 unique terms )
Terms Based on Experimental Evidence ( 8 terms )
Molecular Function
CV term Evidence References
glutamate receptor activity inferred from direct assay (Schuster et al., 1991, Broadie and Bate, 1993)
Biological Process
CV term Evidence References
regulation of neurotransmitter secretion inferred from genetic interaction with Exn, cac (Frank et al., 2009) regulation of synaptic activity inferred from direct assay (Marie et al., 2010) inferred from mutant phenotype (Tsurudome et al., 2010) synaptic transmission inferred from direct assay (Marie et al., 2010) inferred from mutant phenotype (Reiff et al., 2002)
Cellular Component
CV term Evidence References
neuromuscular junction inferred from direct assay (Karr et al., 2009, Kohsaka et al., 2007, Rasse et al., 2005) plasma membrane inferred from direct assay AND inferred from sequence or structural similarity with rat Grik5 (Schuster et al., 1991) postsynaptic density inferred from direct assay (Rasse et al., 2005) colocalizes_with postsynaptic membrane inferred from direct assay (Kohsaka et al., 2007)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
extracellular-glutamate-gated ion channel activity inferred from electronic annotation with InterPro:IPR001320, InterPro:IPR001508, InterPro:IPR019594 (FlyBase Curators et al., 2004-) ionotropic glutamate receptor activity inferred from electronic annotation with InterPro:IPR001320, InterPro:IPR019594 (FlyBase Curators et al., 2004-) kainate selective glutamate receptor activity inferred from sequence or structural similarity (Littleton and Ganetzky, 2000)
Biological Process
CV term Evidence References
ion transport inferred from electronic annotation with InterPro:IPR001508 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions GluRIIA allele Gene References GluRIIAAD9 pAbp (Sigrist et al., 2002) GluRIIAM614R.Scer\UAS.T:Hsap\MYC CaMKII (Haghighi et al., 2003) wit (Haghighi et al., 2003) GluRIIASP16 CaMKII (Haghighi et al., 2003) wit (Haghighi et al., 2003) unspecified GluRIIB (DiAntonio et al., 1997) Pak (Albin and Davis, 2004)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59956 DroID - A comprehensive database of gene and protein interactions. • FBgn0004620 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33788
Orthologs
Genome-wide drosophilid orthologs	Dgri\GH11034 Dmoj\GI17553 Dvir\GJ15538 Dwil\GK14683
Curated drosophilid orthologs	Dpse\GA20012
Linkouts	OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0242581 FBgn0216689 FBgn0202731 FBgn0194738 FBgn0173466 FBgn0080008 FBgn0163950 FBgn0140297 FBgn0118515 FBgn0117213 FBgn0092597
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	27497 y1 v1; P{TRiP.JF02647}attP2 23757 y1 w67c23; Mi{ET1}GluRIIAMB01746
VDRC	v101686 P{KK105437}VIE-260B
Genomic Clones ( 1 )
	BACR35L07 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 49 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT21373 RE27895
Other clones	DPiM_AT21373
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	EC051159 EC056174 EK057607 RP003009613 RP003073289 RP003076653 RP003094984 RP003095274 RP003100182 RP003102373 RP003105104 RP003116795 RP003123330 RP003129806 RP003136729 RP003145510 RP003171364 RP003186189 RP003194115 RP003198160 RP003205728 RP003248561 RP003253140 RP003254777 RP003255201 RP003269348 RP003305665 RP003309223 RP003314075 RP003326044 RP003327577 RP003346610 RP003356456 RP003422977 RP003443332 RP003480632 RP003528420 RP003536371 RP003592110 RP003593504 RP003598079 RP003609286 RP003613130 RP003619033 RP003644717 RP003669695
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0004620 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33788
Antibody Information
	monoclonal (Marrus et al., 2004)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: GluRIIA CG6992 (Skupski, 1999.11)
Source for database merge of
Additional comments
Other Comments
	GluRIIC is required for synaptic localisation of GluRIIA and GluRIIB proteins. Either GluRIIA or GluRIIB, but not both, is required for synaptic localisation of GluRIIC protein. GluRIIA and GluRIIB proteins compete with each other for access to GluRIIC protein and subsequent localisation to the synapse. (Marrus et al., 2004) Study of mutants reveals that a decrease in postsynaptic receptors leads to an increase in presynaptic transmitter release, indicating that postsynaptic activity controls a retrograde signal that regulates presynaptic function. (Petersen et al., 1997) Developmental changes of GluRIIA distribution in wild-type embryos are characterised. GluRIIA receptors are found clustered in the non-nerve-contacted areas at the beginning of synaptogenesis. As synapse formation proceeds these clusters disperse and are found at the neuromuscular junction. By rearing parats1 embryos, at restrictive temperatures, starting at different times during synaptogenesis, it is found that neural activity at a certain period of development profoundly affects the distribution of GluRIIA receptors. (Saitoe et al., 1997) Temporal and spatial expression patterns during embryogenesis and in larval muscle are determined. (Currie et al., 1995) Glutamate receptor channels in Drosophila embryos and larvae have been studied using the patch-clamp technique. (Nishikawa and Kidokoro, 1995) Receptor localization can be determined by application of L-glutamate and monitering with patch clamping techniques. (Broadie and Bate, 1993) In aneural pros mutants functional glutamate receptors are expressed at normal time and distribution over the muscle surface but subsequently fail to cluster to the neuromuscular junction as they would in wild type. The second phase of glutamate receptor synthesis characteristic of wild type fails to occur. The few pros mutants where innervation occurs, but is delayed, show late clustering and late second phase synthesis of glutamate receptors, indicating that these events are innervation-dependent. Likewise, if the neuromuscular junction occurs at an aberrant site, so does the glutamate receptor cluster. (Broadie and Bate, 1993) GluRIIA expression in the postsynaptic membrane is reduced by changes in presynaptic electrical activity. Presynaptic electrical activity during embryonic synaptogenesis is constitutively required for GluRIIA expression at the NMJ and to induce receptor clustering at the NMJ. (Broadie and Bate, 1993) GluRIIA has been cloned and sequenced. (Schuster et al., 1991)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_078760 RefSeq (Proteins) • NP_523484 DDBJ / EMBL / GenBank • AAA28574 AAF52268 AAQ22475 BI229985 BT010006 CS133219 M73271 Entrez Gene - A searchable database of RefSeq genes. • 33788 UniProtKB/TrEMBL • Q9VMP4 Q24351
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ionotropic glutamate receptor (IPR001320) NMDA receptor (IPR001508) Extracellular ligand-binding receptor (IPR001828) Glutamate receptor, L-glutamate/glycine-binding (IPR019594)
Linkouts
	BioGRID - A database of protein and genetic interactions • 59956 DroID - A comprehensive database of gene and protein interactions. • FBgn0004620 DRSC - Results from RNAi screens. • FBgn0004620 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0004620 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6992-RI FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0004620 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33788 Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /hjmuller/glutrc1.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33788 modMine - Data generated by the modENCODE project. • FBgn0004620 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0242581 FBgn0216689 FBgn0202731 FBgn0194738 FBgn0173466 FBgn0080008 FBgn0163950 FBgn0140297 FBgn0118515 FBgn0117213 FBgn0092597
Synonyms & Secondary IDs ( 29 )
Reported As
Symbol Synonym	CG6992 (Benton et al., 2009, Keleman et al., 2009.8.5, Perkins et al., 2009) DGluR2a (Rohrbough et al., 1999) DgluRII (Kaufmann et al., 2002) DGluR-II (Saitoe et al., 1997, Lenz-Bohme et al., 1997, Currie et al., 1995, Schmitt et al., 1993, Ultsch et al., 1993, Schuster et al., 1993, Henneberry, 1992, Schuster et al., 1991, ) dGluRII (Fernandes and Keshishian, 1995) DGluR-IIA (Sigrist et al., 2003, Thiel et al., 2002, Sigrist et al., 2001, Saitoe et al., 2001, Schuster et al., 2001, Schuster et al., 1999, Steinert and Schuster, 2003) D-GluRIIA (Chan et al., 2003) dglurIIA (Reiff et al., 2002) dglur-IIA (Sigrist et al., 2002, Sigrist et al., 2000, Steinert et al., 2006) dGluRIIA (Ma et al., 2001, Middleton et al., 2006) DGluRIIA (Griffith, 2004, Marrus et al., 2004, Haghighi et al., 2003, Packard et al., 2002, Saitoe et al., 2001, Wan et al., 2000, DiAntonio et al., 1999, Davis and Goodman, 1998, Davis et al., 1998, Petersen et al., 1997, DiAntonio et al., 1997, DiAntonio et al., 1997, Rivlin et al., 2004, van der Plas et al., 2006, Guerrero et al., 2005, Giagtzoglou et al., 2009, Wairkar et al., 2008, Lee et al., 2008, Owald et al., 2010) DGluRIIa (Viquez et al., 2009) GluR (Fergestad et al., 1999, Broadie and Bate, 1993, Heckscher et al., 2007, Kazama et al., 2003) GluR2a (Rikhy et al., 2002) GluRIIa (Kuromi et al., 2010) GluRII (Sanyal et al., 2004, Wiggin et al., 2005) Glu-RII   GluRIIa (van Roessel et al., 2004, Koh et al., 2004, Menon et al., 2004) GluRII-A (Ruiz-Canada et al., 2004, Pielage et al., 2006) GlurIIA (Featherstone et al., 2002) glurIIA (Featherstone et al., 2001) Glu-RIIA (Dulcis and Levine, 2005) GluRIIA (Kurshan et al., 2009, Bogdanik et al., 2008, Dudu et al., 2006, Ataman et al., 2006, Kittel et al., 2006, Kittel et al., 2006, Augustin et al., 2007, Haas et al., 2007, Liebl et al., 2008, Chen et al., 2005, Rohrbough et al., 2004, Rasse et al., 2005, Rohrbough et al., 2007, Schmid et al., 2006, Sandmann et al., 2006, Kohsaka et al., 2007, Li et al., 2007, Heckscher et al., 2007, Ataman et al., 2008, Pan and Broadie, 2007, Benton et al., 2009, Chen and Featherstone, 2005, Frank et al., 2009, Schmid et al., 2008, Karr et al., 2009, Ramachandran et al., 2009, Ren et al., 2009, Lin et al., 2009, Zeitlinger et al., 2007, Chai et al., 2008, Chang et al., 2008, Pack-Chung et al., 2007, Frank et al., 2006, Dickman and Davis, 2009, Renden and Broadie, 2003, Liebl and Featherstone, 2005, Chen et al., 2010, Higashi-Kovtun et al., 2010, Wang et al., 2010, Marie et al., 2010, Zhang et al., 2007, Croset et al., 2010, Tsurudome et al., 2010, Morimoto et al., 2010, Pilgram et al., 2011, Romero et al., 2008, Kazama et al., 2003, Nair et al., 2007, Sun et al., 2011, Müller et al., 2011) GluR-IIA (Rasse et al., 2005) gluriia (Morimoto-Tanifuji et al., 2004) unnamed (Landmesser, 1998, Nishikawa and Kidokoro, 1995)
Name Synonym	glutamate IIA receptor (Dulcis and Levine, 2005) glutamate receptor (Verstreken and Bellen, 2002) Glutamate receptor IIA
Secondary FlyBase IDs
References ( 144 )
Generate a list of	All references relating to this gene ( 144 )
List References by type	Research paper  ( 105 ) Supplementary material  ( 5 ) Review  ( 10 ) Personal communication to FlyBase  ( 5 ) Abstract  ( 12 ) Curated genome annotation  ( 2 ) Letter  ( 1 ) Computer file  ( 2 ) Automatic genome annotation  ( 1 )
Recent research papers ( 12 )
	Müller et al., 2011, Neuron 69(4): 749--762 Rab3-GAP Controls the Progression of Synaptic Homeostasis at a Late Stage of Vesicle Release. [FBrf0213055] Pilgram et al., 2011, J. Neurosci. 31(2): 492--500 The RhoGAP crossveinless-c Interacts with Dystrophin and Is Required for Synaptic Homeostasis at the Drosophila Neuromuscular Junction. [FBrf0212767] Sun et al., 2011, J. Neurosci. 31(2): 687--699 Neuroligin 2 is required for synapse development and function at the Drosophila neuromuscular junction. [FBrf0212770] Chen et al., 2010, PLoS ONE 5(6): e11115 Neurexin in embryonic Drosophila neuromuscular junctions. [FBrf0211087] Croset et al., 2010, PLoS Genet. 6(8): Ancient protostome origin of chemosensory ionotropic glutamate receptors and the evolution of insect taste and olfaction. [FBrf0211681] Higashi-Kovtun et al., 2010, J. Neurosci. 30(15): 5253--5268 Importin-beta11 regulates synaptic phosphorylated mothers against decapentaplegic, and thereby influences synaptic development and function at the Drosophila neuromuscular junction. [FBrf0210588] Kuromi et al., 2010, Europ. J. Neurosci. 32(3): 335--346 Two types of Ca channel linked to two endocytic pathways coordinately maintain synaptic transmission at the Drosophila synapse. [FBrf0211498] Marie et al., 2010, J. Neurosci. 30(24): 8071--8082 Synaptic homeostasis is consolidated by the cell fate gene gooseberry, a Drosophila pax3/7 homolog. [FBrf0211066] Morimoto et al., 2010, Neuroscience 165(4): 1284--1292 Subunit-specific and homeostatic regulation of glutamate receptor localization by CaMKII in Drosophila neuromuscular junctions. [FBrf0209866] Owald et al., 2010, J. Cell Biol. 188(4): 565--579 A Syd-1 homologue regulates pre- and postsynaptic maturation in Drosophila. [FBrf0210057] Tsurudome et al., 2010, Neuron 68(5): 879--893 The Drosophila miR-310 Cluster Negatively Regulates Synaptic Strength at the Neuromuscular Junction. [FBrf0212495] Wang et al., 2010, J. Cell Sci. 123(9): 1546--1556 Drosophila twinfilin is required for cell migration and synaptic endocytosis. [FBrf0210650] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...