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Gene Dmel\Bx42

General Information
Symbol	Dmel\Bx42	Species	D. melanogaster
Name	Bx42	Annotation symbol	CG8264
Feature type	protein_coding_gene	FlyBase ID	FBgn0004856
Gene Model Status	Current	Stock availability	4 publicly available
Also Known As	Skip
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	8C9-8C9	Sequence location	X:8,998,351..9,000,635 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Bx42 is referred to in FlyBase by the symbol Dmel\Bx42 (CG8264, FBgn0004856). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: eye-antennal disc development; embryonic development via the syncytial blastoderm. 6 alleles are reported. The phenotypes of these alleles are annotated with: organ system subdivision; adult segment; adult mesothoracic segment; presumptive embryonic/larval nervous system; organ system; non-connected developing system; gland; mouthpart; external compound sense organ; presumptive embryonic/larval peripheral nervous system. It has one annotated transcript and one annotated polypeptide. Protein features are: SKI-interacting protein SKIP, SNW domain; SKI-interacting protein, SKIP. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1637100_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Bx42. Gene sequence location is X:8998351..9000635.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01	Sequence features BKN21649 HFA17743
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 8C9-8C9   Limits computationally determined from genome sequence between P{EP}CG10962EP1565&P{EP}EP1030 and P{EP}EP1450&P{EP}EP1356
Experimentally Determined Cytological Location
Cytogenetic map Notes References 8C7-8C8   (determined by in situ hybridisation)   (Wieland et al., 1992)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Bx42 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.40
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Bx42-RA FBtr0071350  NM_078538   1953   547
Additional Transcript Data & Comments
Reported size (kB)	2.2, 1.9 (northern blot) (Wieland et al., 1992)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Bx42-PA   FBpp0071285   61.2   547   9.97     NP_511093   AAF46444
Additional Polypeptide Data & Comments
Reported size (kDa)	547 (aa); 61 (kD predicted) (Wieland et al., 1992) 66 (kD observed) (Frasch and Saumweber, 1989)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • SKI-interacting protein SKIP, SNW domain (IPR004015) SKI-interacting protein, SKIP (IPR017862)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA263713   AA264353   AA392337   AA393027   AA440907   AA441006   AA567646   AA802525   AA802532   AA803192   AA817533   AA820103   AA820615   AA941369   AA941838   AA942453   AA949470   AA951651   AA951652   AA951832   AA978862   AA979535   AA979622   AE014298 AAF46444   AI294896   AI295774   AI454961   AI455293   AI512355   AI512770   AI512787   AI516051   AI516364   AI516378   AI518866   AI519282   AI531721   AY113364 AAM29369   BI163000   BI163713   BI168645   BI170733   BI228403   BI229942   BI231583   BI232412   BI236864   BI238651   BI241180   BI242443   BI242813   BI243557   BI352278   BI353750   BI361892   BI362721   BI365091   BI366410   BI368848   BI369117   BI372625   BI481762   BI482594   BI486281   CO274073   EC072031   EC254992   ES696598   GH760335   GH803432   GH814139   X64536 CAA45834
UniProtKB/Swiss-Prot	P39736
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
No Assay Recorded Stage Tissue/Position (including subcellular localization) Reference embryonic stage   organism | ubiquitous   (Wieland et al., 1992)
Additional Descriptive Data
	Bx42 transcripts are present throughout development and the 1.9 kb transcript is always nearly twice as prevalent as the 2.2 kb transcript. In situ hybridization shows that the RNA is ubiquitously distributed up to embryonic stage 16. (Wieland et al., 1992)
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
immunolocalization Stage Tissue/Position (including subcellular localization) Reference embryonic stage     (Frasch and Saumweber, 1989) embryonic stage 5     (Frasch and Saumweber, 1989) third instar larval stage   embryonic/larval salivary gland   (Frasch and Saumweber, 1989) adult stage & oogenesis   nurse cell   (Frasch and Saumweber, 1989) follicle cell   (Frasch and Saumweber, 1989)
Additional Descriptive Data
	During oogenesis, observed in nuclei of follicle cells and nurse cells. In embryos, observed in nuclei of cells at cellular blastoderm; expressed throughout embryonic development. In larval salivary glands, localized to polytene chromosomes. (Frasch and Saumweber, 1989)
Marker for
Subcellular Localization
CV Term	nucleus interphase chromosome (Frasch and Saumweber, 1989)
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0004856    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0004856 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0004856 expression level Developmental Stage   Expression Level embryo 00-02hr    8347 embryo 02-04hr    13313 embryo 04-06hr    11276 embryo 06-08hr    9873 embryo 08-10hr    8777 embryo 10-12hr    8393 embryo 12-14hr    5009 embryo 14-16hr    5217 embryo 16-18hr    3803 embryo 18-20hr    3375 embryo 20-22hr    4504 embryo 22-24hr    3739 larva L1    2337 larva L2    1946 larva L3 12hr old    1564 larva L3 puffstage 1-2    1626 larva L3 puffstage 3-6    2211 larva L3 puffstage 7-9    2413 white prepupae new    2511 white prepupae 12hr    2905 white prepupae 24hr    3111 pupae 2d postWPP    2384 pupae 3d postWPP    1392 pupae 4d postWPP    1405 adult male 01day    1506 adult male 05day    1640 adult male 30day    1460 adult female 01day    3270 adult female 05day    4467 adult female 30day    4821 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (8347) embryo 02-04hr  (13313) embryo 04-06hr  (11276) embryo 06-08hr  (9873) embryo 08-10hr  (8777) embryo 10-12hr  (8393) embryo 12-14hr  (5009) embryo 14-16hr  (5217) embryo 16-18hr  (3803) embryo 18-20hr  (3375) embryo 20-22hr  (4504) embryo 22-24hr  (3739) larva L1  (2337) larva L2  (1946) larva L3 12hr old  (1564) larva L3 puffstage 1-2  (1626) larva L3 puffstage 3-6  (2211) larva L3 puffstage 7-9  (2413) white prepupae new  (2511) white prepupae 12hr  (2905) white prepupae 24hr  (3111) pupae 2d postWPP  (2384) pupae 3d postWPP  (1392) pupae 4d postWPP  (1405) adult male 01day  (1506) adult male 05day  (1640) adult male 30day  (1460) adult female 01day  (3270) adult female 05day  (4467) adult female 30day  (4821) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (8347) embryo 02-04hr  (13313) embryo 04-06hr  (11276) embryo 06-08hr  (9873) embryo 08-10hr  (8777) embryo 10-12hr  (8393) embryo 12-14hr  (5009) embryo 14-16hr  (5217) embryo 16-18hr  (3803) embryo 18-20hr  (3375) embryo 20-22hr  (4504) embryo 22-24hr  (3739) larva L1  (2337) larva L2  (1946) larva L3 12hr old  (1564) larva L3 puffstage 1-2  (1626) larva L3 puffstage 3-6  (2211) larva L3 puffstage 7-9  (2413) white prepupae new  (2511) white prepupae 12hr  (2905) white prepupae 24hr  (3111) pupae 2d postWPP  (2384) pupae 3d postWPP    1392 pupae 4d postWPP  1405 adult male 01day  1506 adult male 05day  (1640) adult male 30day  1460 adult female 01day  (3270) adult female 05day  (4467) adult female 30day  (4821) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    8347 embryo 02-04hr  (13313) embryo 04-06hr  (11276) embryo 06-08hr    9873 embryo 08-10hr    8777 embryo 10-12hr    8393 embryo 12-14hr    5009 embryo 14-16hr    5217 embryo 16-18hr    3803 embryo 18-20hr    3375 embryo 20-22hr    4504 embryo 22-24hr    3739 larva L1    2337 larva L2    1946 larva L3 12hr old    1564 larva L3 puffstage 1-2    1626 larva L3 puffstage 3-6    2211 larva L3 puffstage 7-9    2413 white prepupae new    2511 white prepupae 12hr    2905 white prepupae 24hr    3111 pupae 2d postWPP    2384 pupae 3d postWPP    1392 pupae 4d postWPP    1405 adult male 01day    1506 adult male 05day    1640 adult male 30day    1460 adult female 01day    3270 adult female 05day    4467 adult female 30day    4821 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    8347 embryo 02-04hr    13313 embryo 04-06hr    11276 embryo 06-08hr    9873 embryo 08-10hr    8777 embryo 10-12hr    8393 embryo 12-14hr    5009 embryo 14-16hr    5217 embryo 16-18hr    3803 embryo 18-20hr    3375 embryo 20-22hr    4504 embryo 22-24hr    3739 larva L1    2337 larva L2    1946 larva L3 12hr old    1564 larva L3 puffstage 1-2    1626 larva L3 puffstage 3-6    2211 larva L3 puffstage 7-9    2413 white prepupae new    2511 white prepupae 12hr    2905 white prepupae 24hr    3111 pupae 2d postWPP    2384 pupae 3d postWPP    1392 pupae 4d postWPP    1405 adult male 01day    1506 adult male 05day    1640 adult male 30day    1460 adult female 01day    3270 adult female 05day    4467 adult female 30day    4821 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0004856 expression level Developmental Stage   Expression Level embryo 00-02hr    8347 embryo 02-04hr    13313 embryo 04-06hr    11276 embryo 06-08hr    9873 embryo 08-10hr    8777 embryo 10-12hr    8393 embryo 12-14hr    5009 embryo 14-16hr    5217 embryo 16-18hr    3803 embryo 18-20hr    3375 embryo 20-22hr    4504 embryo 22-24hr    3739 larva L1    2337 larva L2    1946 larva L3 12hr old    1564 larva L3 puffstage 1-2    1626 larva L3 puffstage 3-6    2211 larva L3 puffstage 7-9    2413 white prepupae new    2511 white prepupae 12hr    2905 white prepupae 24hr    3111 pupae 2d postWPP    2384 pupae 3d postWPP    1392 pupae 4d postWPP    1405 adult male 01day    1506 adult male 05day    1640 adult male 30day    1460 adult female 01day    3270 adult female 05day    4467 adult female 30day    4821 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (8347) embryo 02-04hr  (13313) embryo 04-06hr  (11276) embryo 06-08hr  (9873) embryo 08-10hr  (8777) embryo 10-12hr  (8393) embryo 12-14hr  (5009) embryo 14-16hr  (5217) embryo 16-18hr  (3803) embryo 18-20hr  (3375) embryo 20-22hr  (4504) embryo 22-24hr  (3739) larva L1  (2337) larva L2  (1946) larva L3 12hr old  (1564) larva L3 puffstage 1-2  (1626) larva L3 puffstage 3-6  (2211) larva L3 puffstage 7-9  (2413) white prepupae new  (2511) white prepupae 12hr  (2905) white prepupae 24hr  (3111) pupae 2d postWPP  (2384) pupae 3d postWPP  (1392) pupae 4d postWPP  (1405) adult male 01day  (1506) adult male 05day  (1640) adult male 30day  (1460) adult female 01day  (3270) adult female 05day  (4467) adult female 30day  (4821) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (8347) embryo 02-04hr  (13313) embryo 04-06hr  (11276) embryo 06-08hr  (9873) embryo 08-10hr  (8777) embryo 10-12hr  (8393) embryo 12-14hr  (5009) embryo 14-16hr  (5217) embryo 16-18hr  (3803) embryo 18-20hr  (3375) embryo 20-22hr  (4504) embryo 22-24hr  (3739) larva L1  2337 larva L2  1946 larva L3 12hr old  1564 larva L3 puffstage 1-2  1626 larva L3 puffstage 3-6  2211 larva L3 puffstage 7-9  2413 white prepupae new  (2511) white prepupae 12hr  (2905) white prepupae 24hr  (3111) pupae 2d postWPP  2384 pupae 3d postWPP    1392 pupae 4d postWPP  1405 adult male 01day  1506 adult male 05day  1640 adult male 30day  1460 adult female 01day  (3270) adult female 05day  (4467) adult female 30day  (4821) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    8347 embryo 02-04hr  13313 embryo 04-06hr  11276 embryo 06-08hr    9873 embryo 08-10hr    8777 embryo 10-12hr    8393 embryo 12-14hr    5009 embryo 14-16hr    5217 embryo 16-18hr    3803 embryo 18-20hr    3375 embryo 20-22hr    4504 embryo 22-24hr    3739 larva L1    2337 larva L2    1946 larva L3 12hr old    1564 larva L3 puffstage 1-2    1626 larva L3 puffstage 3-6    2211 larva L3 puffstage 7-9    2413 white prepupae new    2511 white prepupae 12hr    2905 white prepupae 24hr    3111 pupae 2d postWPP    2384 pupae 3d postWPP    1392 pupae 4d postWPP    1405 adult male 01day    1506 adult male 05day    1640 adult male 30day    1460 adult female 01day    3270 adult female 05day    4467 adult female 30day    4821 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    8347 embryo 02-04hr    13313 embryo 04-06hr    11276 embryo 06-08hr    9873 embryo 08-10hr    8777 embryo 10-12hr    8393 embryo 12-14hr    5009 embryo 14-16hr    5217 embryo 16-18hr    3803 embryo 18-20hr    3375 embryo 20-22hr    4504 embryo 22-24hr    3739 larva L1    2337 larva L2    1946 larva L3 12hr old    1564 larva L3 puffstage 1-2    1626 larva L3 puffstage 3-6    2211 larva L3 puffstage 7-9    2413 white prepupae new    2511 white prepupae 12hr    2905 white prepupae 24hr    3111 pupae 2d postWPP    2384 pupae 3d postWPP    1392 pupae 4d postWPP    1405 adult male 01day    1506 adult male 05day    1640 adult male 30day    1460 adult female 01day    3270 adult female 05day    4467 adult female 30day    4821 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0004856    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0004856 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0004856 expression level Tissue   Expression Level Larval Central Nervous System    270.875 Larval Midgut    113.1 Larval Hindgut    120.9 Larval Malpighian Tubules    129 Larval Fat Body    116.9 Larval Salivary Gland    209.9 Larval Trachea    202.975 Larval Carcass    111.8 Adult Head    124.5 Adult Eye    188.85 Adult Brain    194.5 Adult Thoracic-Abdominal Ganglion    166.4 Adult Crop    143.2 Adult Midgut    157.1 Adult Hindgut    144.7 Adult Malpighian Tubules    183.9 Adult Fat Body    131 Adult Salivary Gland    218.3 Adult Heart    101.6 Adult VirginFemale Spermatheca    200.1 Adult InseminatedFemale Spermatheca    192.6 Adult Ovary    263.7 Adult Testis    54.1 Adult Male Accessory Gland    177 Adult Carcass    124.2 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    270.875 Larval Midgut    113.1 Larval Hindgut    120.9 Larval Malpighian Tubules    129 Larval Fat Body    116.9 Larval Salivary Gland    209.9 Larval Trachea    202.975 Larval Carcass    111.8 Adult Head    124.5 Adult Eye    188.85 Adult Brain    194.5 Adult Thoracic-Abdominal Ganglion    166.4 Adult Crop    143.2 Adult Midgut    157.1 Adult Hindgut    144.7 Adult Malpighian Tubules    183.9 Adult Fat Body    131 Adult Salivary Gland    218.3 Adult Heart    101.6 Adult VirginFemale Spermatheca    200.1 Adult InseminatedFemale Spermatheca    192.6 Adult Ovary    263.7 Adult Testis    54.1 Adult Male Accessory Gland    177 Adult Carcass    124.2 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    270.875 Larval Midgut    113.1 Larval Hindgut    120.9 Larval Malpighian Tubules    129 Larval Fat Body    116.9 Larval Salivary Gland    209.9 Larval Trachea    202.975 Larval Carcass    111.8 Adult Head    124.5 Adult Eye    188.85 Adult Brain    194.5 Adult Thoracic-Abdominal Ganglion    166.4 Adult Crop    143.2 Adult Midgut    157.1 Adult Hindgut    144.7 Adult Malpighian Tubules    183.9 Adult Fat Body    131 Adult Salivary Gland    218.3 Adult Heart    101.6 Adult VirginFemale Spermatheca    200.1 Adult InseminatedFemale Spermatheca    192.6 Adult Ovary    263.7 Adult Testis    54.1 Adult Male Accessory Gland    177 Adult Carcass    124.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    270.875 Larval Midgut    113.1 Larval Hindgut    120.9 Larval Malpighian Tubules    129 Larval Fat Body    116.9 Larval Salivary Gland    209.9 Larval Trachea    202.975 Larval Carcass    111.8 Adult Head    124.5 Adult Eye    188.85 Adult Brain    194.5 Adult Thoracic-Abdominal Ganglion    166.4 Adult Crop    143.2 Adult Midgut    157.1 Adult Hindgut    144.7 Adult Malpighian Tubules    183.9 Adult Fat Body    131 Adult Salivary Gland    218.3 Adult Heart    101.6 Adult VirginFemale Spermatheca    200.1 Adult InseminatedFemale Spermatheca    192.6 Adult Ovary    263.7 Adult Testis    54.1 Adult Male Accessory Gland    177 Adult Carcass    124.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0004856 expression level Tissue   Expression Level Larval Central Nervous System    270.875 Larval Midgut    113.1 Larval Hindgut    120.9 Larval Malpighian Tubules    129 Larval Fat Body    116.9 Larval Salivary Gland    209.9 Larval Trachea    202.975 Larval Carcass    111.8 Adult Head    124.5 Adult Eye    188.85 Adult Brain    194.5 Adult Thoracic-Abdominal Ganglion    166.4 Adult Crop    143.2 Adult Midgut    157.1 Adult Hindgut    144.7 Adult Malpighian Tubules    183.9 Adult Fat Body    131 Adult Salivary Gland    218.3 Adult Heart    101.6 Adult VirginFemale Spermatheca    200.1 Adult InseminatedFemale Spermatheca    192.6 Adult Ovary    263.7 Adult Testis    54.1 Adult Male Accessory Gland    177 Adult Carcass    124.2 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    270.875 Larval Midgut    113.1 Larval Hindgut    120.9 Larval Malpighian Tubules    129 Larval Fat Body    116.9 Larval Salivary Gland    209.9 Larval Trachea    202.975 Larval Carcass    111.8 Adult Head    124.5 Adult Eye    188.85 Adult Brain    194.5 Adult Thoracic-Abdominal Ganglion    166.4 Adult Crop    143.2 Adult Midgut    157.1 Adult Hindgut    144.7 Adult Malpighian Tubules    183.9 Adult Fat Body    131 Adult Salivary Gland    218.3 Adult Heart    101.6 Adult VirginFemale Spermatheca    200.1 Adult InseminatedFemale Spermatheca    192.6 Adult Ovary    263.7 Adult Testis    54.1 Adult Male Accessory Gland    177 Adult Carcass    124.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    270.875 Larval Midgut    113.1 Larval Hindgut    120.9 Larval Malpighian Tubules    129 Larval Fat Body    116.9 Larval Salivary Gland    209.9 Larval Trachea    202.975 Larval Carcass    111.8 Adult Head    124.5 Adult Eye    188.85 Adult Brain    194.5 Adult Thoracic-Abdominal Ganglion    166.4 Adult Crop    143.2 Adult Midgut    157.1 Adult Hindgut    144.7 Adult Malpighian Tubules    183.9 Adult Fat Body    131 Adult Salivary Gland    218.3 Adult Heart    101.6 Adult VirginFemale Spermatheca    200.1 Adult InseminatedFemale Spermatheca    192.6 Adult Ovary    263.7 Adult Testis    54.1 Adult Male Accessory Gland    177 Adult Carcass    124.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    270.875 Larval Midgut    113.1 Larval Hindgut    120.9 Larval Malpighian Tubules    129 Larval Fat Body    116.9 Larval Salivary Gland    209.9 Larval Trachea    202.975 Larval Carcass    111.8 Adult Head    124.5 Adult Eye    188.85 Adult Brain    194.5 Adult Thoracic-Abdominal Ganglion    166.4 Adult Crop    143.2 Adult Midgut    157.1 Adult Hindgut    144.7 Adult Malpighian Tubules    183.9 Adult Fat Body    131 Adult Salivary Gland    218.3 Adult Heart    101.6 Adult VirginFemale Spermatheca    200.1 Adult InseminatedFemale Spermatheca    192.6 Adult Ovary    263.7 Adult Testis    54.1 Adult Male Accessory Gland    177 Adult Carcass    124.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    124.5   NA  Eye    188.85   NA  Brain    194.5   270.875  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    166.4   NA  Crop    143.2   113.1  Midgut    157.1   120.9  Hindgut    144.7   129  Malpighian Tubules    183.9   116.9  Fat Body    131   209.9  Salivary Gland    218.3   NA  Heart    101.6   202.975  Trachea    NA   NA  VirginFemale Spermatheca    200.1   NA  InseminatedFemale Spermatheca    192.6   NA  Ovary    263.7   NA  Testis    54.1   NA  Male Accessory Gland    177   111.8  Carcass    124.2 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_17
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0004856 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8264-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4ptc-559.1 Bx42dsRNA.Scer\UAS lethal | embryonic stage, with Scer\GAL4T80 Bx42dsRNA.Scer\UAS lethal | embryonic stage | partially, with Scer\GAL4αTub84B.PL Bx42dsRNA.Scer\UAS lethal | partially, with Scer\GAL4G6.1 Bx42dsRNA.Scer\UAS lethal | partially | pupal stage, with Scer\GAL4ey.PH Bx42dsRNA.Scer\UAS viable Bx42f04222 viable, with Scer\GAL4pnr-MD237 Bx42GD13866 Sterility Allele fertile Bx42f04222 Other Phenotypes Allele neuroanatomy defective Bx42dsRNA.cIa Phenotype manifest in Allele 1st posterior cell, with Scer\GAL4dpp.blk1 Bx42dsRNA.Scer\UAS antenna | ectopic, with Scer\GAL4ey.PH Bx42dsRNA.Scer\UAS anterior crossvein, with Scer\GAL4dpp.blk1 Bx42dsRNA.Scer\UAS anterior crossvein, with Scer\GAL4ptc-559.1 Bx42dsRNA.Scer\UAS anterior scutellar bristle, with Scer\GAL4ptc-559.1 Bx42dsRNA.Scer\UAS eye, with Scer\GAL4ey.PH Bx42dsRNA.Scer\UAS gnathal segment, with Scer\GAL4ey.PH Bx42dsRNA.Scer\UAS head | P-stage, with Scer\GAL4ey.PH Bx42dsRNA.Scer\UAS leg | ectopic, with Scer\GAL4ptc-559.1 Bx42dsRNA.Scer\UAS mouthpart, with Scer\GAL4ey.PH Bx42dsRNA.Scer\UAS posterior scutellar bristle, with Scer\GAL4ptc-559.1 Bx42dsRNA.Scer\UAS presumptive embryonic/larval central nervous system Bx42dsRNA.cIa presumptive embryonic/larval peripheral nervous system Bx42dsRNA.cIa salivary gland, with Scer\GAL4G6.1 Bx42dsRNA.Scer\UAS wing vein, with Scer\GAL4dpp.blk1 Bx42dsRNA.Scer\UAS wing vein L3, with Scer\GAL4dpp.blk1 Bx42dsRNA.Scer\UAS wing vein L3, with Scer\GAL4ptc-559.1 Bx42dsRNA.Scer\UAS
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of Bx42 Class Mutagen Stocks Known lesion Bx42f04222 piggyBac transposase 2 --
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Bx42 Class Mutagen Stocks Known lesion Bx42HMS00086 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Bx42KK101598 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Bx42dsRNA.cIa in vitro construct - RNAi 0 Yes Bx42dsRNA.Scer\UAS in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes Bx42GD13866 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD13866} NA P{KK101598} NA P{TRiP.HMS00086} NA P{UAS-Bx42.dsRNA.N} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{WH}Bx42f04222 NA
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
embryonic development via the syncytial blastoderm inferred from mutant phenotype (Negeri et al., 2002) eye-antennal disc development inferred from mutant phenotype (Negeri et al., 2002)
Cellular Component
CV term Evidence References
catalytic step 2 spliceosome inferred from direct assay (Herold et al., 2009) precatalytic spliceosome inferred from direct assay (Herold et al., 2009)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
nuclear mRNA splicing, via spliceosome inferred by curator from GO:0071011|GO:0071013 (Herold et al., 2009) inferred from electronic annotation with InterPro:IPR004015, InterPro:IPR017862 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
colocalizes_with nuclear chromatin non-traceable author statement (Negeri et al., 2002) nucleus non-traceable author statement (Swiss-Prot Project Members, 1997.11.1)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Bx42 allele Gene References Bx42dsRNA.Scer\UAS Su(H) (Negeri et al., 2002)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 58295 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0004856 DroID - A comprehensive database of gene and protein interactions. • FBgn0004856 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31840
Orthologs
Genome-wide drosophilid orthologs	Dana\GF19111 Dere\GG19003 Dgri\GH12382 Dmoj\GI15876 Dper\GL12909 Dpse\GA20940 Dsec\GM13680 Dsim\GD24563 Dvir\GJ18702 Dwil\GK16274 Dyak\GE17416
Curated drosophilid orthologs	Dpse\GA20940
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL014528-PA Aedes aegypti (mosquito) AGAP004521-PA Anopheles gambiae (mosquito) XP_623623.1 Apis mellifera (honey bee) XP_001945274.1 Acyrthosiphon pisum (pea aphid) At1g77180.1 Arabidopsis thaliana (wall cress) 36683 Batrachochytrium dendrobatidis (chytrid fungus) 262046 Branchiostoma floridae (lancelet) 277402 Branchiostoma floridae (lancelet) XP_001902829.1 Brugia malayi (roundworm nematode) BGIBMGA008202-PA Bombyx mori (silk worm) ENSBTAP00000010697 Bos taurus (bovine) CAL0006088 Candida albicans (a form of yeast) CN13601 Caenorhabditis brenneri (small nematode) CBP20685 Caenorhabditis briggsae (nematode) CE06519 Caenorhabditis elegans (worm) ENSCAFP00000032704 Canis familiaris (dog) CAGL0M11814g Candida glabrata (haploid yeast) Chro.80502 Cryptosporidium hominis (obligate parasite) ENSCINP00000017139 Ciona intestinalis (sea squirt) JA14589 Caenorhabditis japonica (nematode) cn12081 Cryptococcus neoformans (yeast-like fungus) cgd8_4380 Cryptosporidium parvum (protozoan parasite) CPIJ008316 Culex pipens (mosquito) ENSCPOP00000009556 Cavia porcellus (guinea pig) 116646 Chlamidomonas reinhardtii (green alga) RP45765 Caenorhabditis remanei (nematode) ENSCSAVP00000018802 Ciona savignyi (sedentary tunicate) 153812 Capitella spl (polychaete worm) DDB0191206 Dictyostelium discoideum (amoeba) 309171 Daphnia pulex (daphnia) ENSDARP00000089703 Danio rerio (zebra fish) ENSECAP00000004733 Equus caballus (horse) XP_654738 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000007103 Gymnopilus aculeatus (mushroom) ENSGALP00000017080 Gallus gallus (chicken) 104662 Hypsipyla robusta (cedar shoot borer) ENSP00000261531 Homo sapiens (human) ISCW021146-PA Ixodes scapularis (deer tick) KLLA0F02475g Kluyveromyces lactis (yeast) 233248 Lottia gigantea (owl limpet) 24891 Monocosta brevicollis (choanoflagellate) ENSMODP00000006481 Monodelphis domestica (gray opossum) ENSMMUP00000039874 Macaca mulatta (rhesus monkey) ENSMUSP00000021428 Mus musculus (house mouse) 243279 Nematostella vectensis (starlet anemone) XP_001607473.1 Nasonia vitripennis (wasp) ENSOANP00000017177 Ornithorynchus anatinus (platypus) ENSORLP00000013318 Oryzias latipes (japanese killifish) LOC_Os02g52250.1 Oryza sativa (asian rice) PFB0875c Plasmodium falciparum (protozoal parasite) PHUM001482-PA Pediculus humanus (human body louse) PP05633 Pristionchus pacificus (nematode) 182359 Physcomitrella patens (moss) ENSPPYP00000006859 Pongo pygmaeus (orangutan) 54142 Phytophthora ramorum (sudden oak death pathogen) 115734 Phytophthora sojae (root rot pathogen) 787442 Populus trichocarpa (black cottonwood) ENSPTRP00000011189 Pan troglodytes (chimpanzee) PVX_002605 Plasmodium vivax (protozoal parasite) ENSRNOP00000054619 Rattus norvegicus (norway rat) 4884723 Sorghum bicolor (sorghum) YAL032C Saccharomyces cerevisiae (budding yeast) Smp_105860 Schistosoma mansoni (trematode parasite) SPCC188.11 Schizosaccharomyces pombe (fission yeast) XP_795058.2 Strongylocentrotus purpuratus (purple sea urchin) 51016 Trichoplax adhaerens (metazoa) TA13585 Theileria annulata (apicomplexan parasite) XP_971504.1 Tribolium castaneum (red flour beetle) Tc00.1047053509445.20 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000012580 Tetraodon nigroviridis (green spotted pufferfish) TP02_0511 Theileria parva (parasitic protozoan) 268084 Thalassiosira pseudonana (marine diatom) ENSTRUP00000046157 Takifugu rubripes (pufferfish Takifugu) 172.m00083 Tetrahymena thermophila (ciliate protozoa) 94179.m00294 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000024215 Xenopus tropicalis (frog) YALI0C11715g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV50017 NV12238 LH15057 ISCW021146 FBgn0234883 FBgn0218276 FBgn0205855 FBgn0195897 FBgn0168611 JGI_V11_309171 FBgn0080929 FBgn0150515 FBgn0138625 FBgn0119861 FBgn0111209 FBgn0096122 CPIJ008316 BGIBMGA008202 ACYPI40536 ACYPI010171 GB12341 AGAP004521 AAEL014528 PB22160 PHUM112920 GLEAN_04979
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	18747 w1118 PBac{WH}Bx42f04222 34777 y1 sc* v1; P{TRiP.HMS00086}attP2
Harvard	- PBac{WH}Bx42f04222
VDRC	v107012 P{KK101598}VIE-260B
Genomic Clones ( 2 )
	BACR04L24 BACR39L04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 69 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD22701
Other clones	DPiM_LD22701
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM05765 GM05773 GM10374 GM18636 GM24969 HL01574 LD01382 LD06993 LD07579 LD08915 LD11176 LD12708 LD15744 LD23321 LD24432 LD25485 LD26682 LD27143 LD29484 LD32293 LD32294 LD32559 LD33037 LD34151 LD34319 LD35280 LD38811 LD41787 LD42216 LD42231 LD44209 LD44792 LD44820 LP08379 LP09506 RE02287 RE03181 RE09473 RE12286 RE22462 RE25943 RE27842 RE28474 RE32989 RE35157 RE38201 RE39768 RE40247 RE41224 RE46288 RE47368 RE50318 RE51941 RE54896 RE55208 RE59633 RE64363 RE65307 RE69692 SD02963
Other clones	11987 214321.11 EK113041 RC0-DP0009-150700-021-F11 RP003148321 RP003353347 RP003673545
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0004856 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31840
Antibody Information
	monoclonal (Frasch and Saumweber, 1989) polyclonal (Wieland et al., 1992)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	Embryos derived from homozygous female germline clones show disruptions in dpp target gene expression patterns. (Sharma and Ashe, 2006) RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells. (Boutros et al., 2004) In a sample of 79 genes with multiple introns, 33 showed significant heterogeneity in G+C content among introns of the same gene and significant positive correspondence between the intron and the third codon position G+C content within genes. These results are consistent with selection adding against preferred codons at the start of genes. (Kliman and Eyre-Walker, 1998) Bx42 is present in a set of transcriptionally active puffs on polytene chromosomes. (Wieland et al., 1992) Bx42 binds to the chromosome within 2.5kb 5' of the start of Sgs4 transcription. (Saumweber et al., 1990)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_078538 RefSeq (Proteins) • NP_511093 DDBJ / EMBL / GenBank • AA820103 AAF46444 AAM29369 AI455293 AY113364 CAA45834 X64536 Entrez Gene - A searchable database of RefSeq genes. • 31840 UniProtKB/Swiss-Prot • P39736
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • SKI-interacting protein SKIP, SNW domain (IPR004015) SKI-interacting protein, SKIP (IPR017862)
Linkouts
	BioGRID - A database of protein and genetic interactions • 58295 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0004856 DroID - A comprehensive database of gene and protein interactions. • FBgn0004856 DRSC - Results from RNAi screens. • FBgn0004856 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0004856 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8264-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0004856 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31840 InParanoid A subset of ortholog calls from InParanoid. • AAEL014528-PA Aedes aegypti (mosquito) AGAP004521-PA Anopheles gambiae (mosquito) XP_623623.1 Apis mellifera (honey bee) XP_001945274.1 Acyrthosiphon pisum (pea aphid) At1g77180.1 Arabidopsis thaliana (wall cress) 36683 Batrachochytrium dendrobatidis (chytrid fungus) 262046 Branchiostoma floridae (lancelet) 277402 Branchiostoma floridae (lancelet) XP_001902829.1 Brugia malayi (roundworm nematode) BGIBMGA008202-PA Bombyx mori (silk worm) ENSBTAP00000010697 Bos taurus (bovine) CAL0006088 Candida albicans (a form of yeast) CN13601 Caenorhabditis brenneri (small nematode) CBP20685 Caenorhabditis briggsae (nematode) CE06519 Caenorhabditis elegans (worm) ENSCAFP00000032704 Canis familiaris (dog) CAGL0M11814g Candida glabrata (haploid yeast) Chro.80502 Cryptosporidium hominis (obligate parasite) ENSCINP00000017139 Ciona intestinalis (sea squirt) JA14589 Caenorhabditis japonica (nematode) cn12081 Cryptococcus neoformans (yeast-like fungus) cgd8_4380 Cryptosporidium parvum (protozoan parasite) CPIJ008316 Culex pipens (mosquito) ENSCPOP00000009556 Cavia porcellus (guinea pig) 116646 Chlamidomonas reinhardtii (green alga) RP45765 Caenorhabditis remanei (nematode) ENSCSAVP00000018802 Ciona savignyi (sedentary tunicate) 153812 Capitella spl (polychaete worm) DDB0191206 Dictyostelium discoideum (amoeba) 309171 Daphnia pulex (daphnia) ENSDARP00000089703 Danio rerio (zebra fish) ENSECAP00000004733 Equus caballus (horse) XP_654738 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000007103 Gymnopilus aculeatus (mushroom) ENSGALP00000017080 Gallus gallus (chicken) 104662 Hypsipyla robusta (cedar shoot borer) ENSP00000261531 Homo sapiens (human) ISCW021146-PA Ixodes scapularis (deer tick) KLLA0F02475g Kluyveromyces lactis (yeast) 233248 Lottia gigantea (owl limpet) 24891 Monocosta brevicollis (choanoflagellate) ENSMODP00000006481 Monodelphis domestica (gray opossum) ENSMMUP00000039874 Macaca mulatta (rhesus monkey) ENSMUSP00000021428 Mus musculus (house mouse) 243279 Nematostella vectensis (starlet anemone) XP_001607473.1 Nasonia vitripennis (wasp) ENSOANP00000017177 Ornithorynchus anatinus (platypus) ENSORLP00000013318 Oryzias latipes (japanese killifish) LOC_Os02g52250.1 Oryza sativa (asian rice) PFB0875c Plasmodium falciparum (protozoal parasite) PHUM001482-PA Pediculus humanus (human body louse) PP05633 Pristionchus pacificus (nematode) 182359 Physcomitrella patens (moss) ENSPPYP00000006859 Pongo pygmaeus (orangutan) 54142 Phytophthora ramorum (sudden oak death pathogen) 115734 Phytophthora sojae (root rot pathogen) 787442 Populus trichocarpa (black cottonwood) ENSPTRP00000011189 Pan troglodytes (chimpanzee) PVX_002605 Plasmodium vivax (protozoal parasite) ENSRNOP00000054619 Rattus norvegicus (norway rat) 4884723 Sorghum bicolor (sorghum) YAL032C Saccharomyces cerevisiae (budding yeast) Smp_105860 Schistosoma mansoni (trematode parasite) SPCC188.11 Schizosaccharomyces pombe (fission yeast) XP_795058.2 Strongylocentrotus purpuratus (purple sea urchin) 51016 Trichoplax adhaerens (metazoa) TA13585 Theileria annulata (apicomplexan parasite) XP_971504.1 Tribolium castaneum (red flour beetle) Tc00.1047053509445.20 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000012580 Tetraodon nigroviridis (green spotted pufferfish) TP02_0511 Theileria parva (parasitic protozoan) 268084 Thalassiosira pseudonana (marine diatom) ENSTRUP00000046157 Takifugu rubripes (pufferfish Takifugu) 172.m00083 Tetrahymena thermophila (ciliate protozoa) 94179.m00294 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000024215 Xenopus tropicalis (frog) YALI0C11715g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31840 modMine - Data generated by the modENCODE project. • FBgn0004856 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV50017 NV12238 LH15057 ISCW021146 FBgn0234883 FBgn0218276 FBgn0205855 FBgn0195897 FBgn0168611 JGI_V11_309171 FBgn0080929 FBgn0150515 FBgn0138625 FBgn0119861 FBgn0111209 FBgn0096122 CPIJ008316 BGIBMGA008202 ACYPI40536 ACYPI010171 GB12341 AGAP004521 AAEL014528 PB22160 PHUM112920 GLEAN_04979
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	Bx42 (Negeri et al., 2007, Farny et al., 2008, Taylor-Harding et al., 2004, Moshkin et al., 2009, Zhou et al., 2008) BX42 (Herold et al., 2009) CG8264 (Andersen and Tapon, 2008, Keleman et al., 2009.8.5, Herold et al., 2009, Ni et al., 2011.7.19) Skip (Sharma and Ashe, 2006, Penn et al., 2008) SKIP (Goodfellow et al., 2007, Moshkin et al., 2009)
Name Synonym	Bx42   Ski-interacting protein (Sharma and Ashe, 2006)
Secondary FlyBase IDs
References ( 36 )
Generate a list of	All references relating to this gene ( 36 )
List References by type	Research paper  ( 18 ) Supplementary material  ( 5 ) Personal communication to FlyBase  ( 4 ) Abstract  ( 3 ) FlyBase analysis  ( 1 ) Protein sequence record  ( 1 ) Computer file  ( 1 ) Automatic genome annotation  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 1 )
	Jankovics et al., 2011, PLoS ONE 6(7): e22229 A functional genomic screen combined with time-lapse microscopy uncovers a novel set of genes involved in dorsal closure of Drosophila embryos. [FBrf0214545] Show all research papers ...