Open Close
General Information
Symbol
Dmel\tws
Species
D. melanogaster
Name
twins
Annotation Symbol
CG6235
Feature Type
FlyBase ID
FBgn0004889
Gene Model Status
Stock Availability
Gene Snapshot
twins (tws) encodes a regulatory subunit of protein phosphatase 2A (PP2A) and is involved in many developmental processes and signaling pathways. [Date last reviewed: 2018-09-13]
Also Known As

aar, PP2A, PR55, phosphoprotein phosphatase 2A 55 kDa, l(3)02414

Key Links
Genomic Location
Cytogenetic map
Sequence location
3R:10,126,129..10,139,772 [-]
Recombination map

3-49

RefSeq locus
NT_033777 REGION:10126129..10139772
Sequence
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (18 terms)
Molecular Function (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
inferred from sequence or structural similarity with UniProtKB:P63151
(assigned by UniProt )
inferred from biological aspect of ancestor with PANTHER:PTN000221745
(assigned by GO_Central )
Biological Process (14 terms)
Terms Based on Experimental Evidence (13 terms)
CV Term
Evidence
References
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from genetic interaction with FLYBASE:dsh; FB:FBgn0000499
inferred from genetic interaction with FLYBASE:sgg; FB:FBgn0003371
inferred from genetic interaction with FLYBASE:pan; FB:FBgn0085432
inferred from mutant phenotype
inferred from direct assay
inferred from mutant phenotype
inferred from mutant phenotype
(assigned by UniProt )
inferred from mutant phenotype
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
inferred from biological aspect of ancestor with PANTHER:PTN000221745
(assigned by GO_Central )
Cellular Component (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
inferred from high throughput direct assay
inferred from direct assay
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
inferred from biological aspect of ancestor with PANTHER:PTN000221745
(assigned by GO_Central )
inferred from biological aspect of ancestor with PANTHER:PTN000221745
(assigned by GO_Central )
inferred from sequence or structural similarity with UniProtKB:P63151
(assigned by UniProt )
Protein Family (UniProt)
Belongs to the phosphatase 2A regulatory subunit B family. (P36872)
Summaries
Pathway (FlyBase)
Positive Regulators of Wnt-TCF Signaling Pathway -
Positive regulators of canonical Wnt signaling up-regulate the pathway, resulting in the enhancement of transcriptional regulation mediated by β-catenin (arm).
Positive Regulators of Hedgehog Signaling Pathway -
Positive regulators of hedgehog signaling down-regulation the pathway, enhancing the activation of transcription of hh-responsive genes.
Gene Group (FlyBase)
TWS-PROTEIN PHOSOPHATASE 2A COMPLEX -
tws-PP2A is a serine/threonine phosphatase complex characterized by the presence of a tws regulatory B subunit. (Adapted from FBrf0232706.)
Protein Function (UniProtKB)
Could perform a substrate recognition function or could be responsible for targeting the enzyme complex to the appropriate subcellular compartment.
(UniProt, P36872)
Summary (Interactive Fly)

Protein phosphatase 2A - B subunit - mutation causes a peripheral nervous system defect similar to those of and - mutation also causes a pattern duplication in imaginal discs

Gene Model and Products
Number of Transcripts
9
Number of Unique Polypeptides
2

Please see the GBrowse view of Dmel\tws or the JBrowse view of Dmel\tws for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Gene model reviewed during 5.46

Gene model reviewed during 5.55

Sequence Ontology: Class of Gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
FBtr0082186
2520
499
FBtr0082188
2896
443
FBtr0082191
2242
443
FBtr0082189
3086
443
FBtr0082190
3819
443
FBtr0082187
3664
499
FBtr0082192
2400
443
FBtr0082193
2300
443
FBtr0345177
3856
499
Additional Transcript Data and Comments
Reported size (kB)

5.0, 3.8-4.0, 3.7, 2.75, 2.5 (northern blot)

Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
FBpp0081664
57.0
499
7.10
FBpp0081666
50.8
443
6.38
FBpp0081669
50.8
443
6.38
FBpp0081667
50.8
443
6.38
FBpp0081668
50.8
443
6.38
FBpp0081665
57.0
499
7.10
FBpp0081670
50.8
443
6.38
FBpp0081671
50.8
443
6.38
FBpp0311386
57.0
499
7.10
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

499 aa isoforms: tws-PA, tws-PF, tws-PI
443 aa isoforms: tws-PB, tws-PC, tws-PD, tws-PE, tws-PG, tws-PH
Additional Polypeptide Data and Comments
Reported size (kDa)

456, 443 (aa); 52, 51 (kD)

443 (aa); 51 (kD predicted)

Comments
External Data
Subunit Structure (UniProtKB)

PP2A exists in several trimeric forms, all of which consist of a core composed of a catalytic subunit associated with a 65 kDa regulatory subunit (PR65) (subunit A). The core complex associates with a third, variable subunit (subunit B), which confers distinct properties to the holoenzyme.

(UniProt, P36872)
Linkouts
Sequences Consistent with the Gene Model
Nucleotide / Polypeptide Records
 
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\tws using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
No Assay Recorded
Stage
Tissue/Position (including subcellular localization)
Reference
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
northern blot
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data

tws transcripts are found at high levels in ovarioles. They are first detected at stage S6 in nurse cells and are later transported to the egg cell. In embryos, they are present at high levels at the syncytial blastoderm stage and then decrease. They are later detected in the migrating gonads, CNS, anal pads, Malpighian tubules, and hindgut. In larvae, transcripts are detected in regions of cell proliferation in the optic lobes. In pupae, they are found in a uniform distribution in imaginal discs and testes.

Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
western blot
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
inferred from high throughput direct assay
inferred from direct assay
Expression Deduced from Reporters
Stage
Tissue/Position (including subcellular localization)
Reference
Stage
Tissue/Position (including subcellular localization)
Reference
medulla

Comment: medulla - photoreceptors?

High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\tws in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 102 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 15 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of tws
Transgenic constructs containing regulatory region of tws
Deletions and Duplications ( 10 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
Sterility
Allele
Other Phenotypes
Allele
Phenotype manifest in
Allele
chromatin & mitotic anaphase
larval brain & nuclear chromosome
mitotic anaphase & neuroblast
mitotic metaphase & neuroblast
nuclear chromosome & mitotic anaphase
spindle & neuroblast
Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (4)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
15 of 15
Yes
Yes
13 of 15
No
Yes
13 of 15
No
Yes
1  
11 of 15
No
Yes
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (4)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
15 of 15
Yes
Yes
13 of 15
No
Yes
12 of 15
No
Yes
10 of 15
No
Yes
Rattus norvegicus (Norway rat) (5)
13 of 13
Yes
Yes
12 of 13
No
Yes
11 of 13
No
Yes
7 of 13
No
Yes
1 of 13
No
Yes
Xenopus tropicalis (Western clawed frog) (5)
13 of 12
Yes
Yes
12 of 12
No
Yes
9 of 12
No
Yes
7 of 12
No
Yes
2 of 12
No
Yes
Danio rerio (Zebrafish) (7)
14 of 15
Yes
Yes
12 of 15
No
Yes
10 of 15
No
Yes
10 of 15
No
Yes
10 of 15
No
Yes
8 of 15
No
Yes
8 of 15
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (1)
14 of 15
Yes
Yes
Arabidopsis thaliana (thale-cress) (2)
9 of 9
Yes
Yes
9 of 9
Yes
Yes
Saccharomyces cerevisiae (Brewer's yeast) (1)
14 of 15
Yes
Yes
Schizosaccharomyces pombe (Fission yeast) (1)
10 of 12
Yes
Yes
Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG091906O8 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Drosophila simulans
Drosophila sechellia
Drosophila erecta
Drosophila yakuba
Drosophila ananassae
Drosophila pseudoobscura pseudoobscura
Drosophila persimilis
Drosophila willistoni
Drosophila virilis
Drosophila mojavensis
Drosophila grimshawi
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915044C )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Glossina morsitans
Tsetse fly
Lucilia cuprina
Australian sheep blowfly
Mayetiola destructor
Hessian fly
Aedes aegypti
Yellow fever mosquito
Anopheles darlingi
American malaria mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W04TK )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Danaus plexippus
Monarch butterfly
Heliconius melpomene
Postman butterfly
Apis florea
Little honeybee
Apis mellifera
Western honey bee
Apis mellifera
Western honey bee
Bombus impatiens
Common eastern bumble bee
Bombus impatiens
Common eastern bumble bee
Bombus terrestris
Buff-tailed bumblebee
Linepithema humile
Argentine ant
Megachile rotundata
Alfalfa leafcutting bee
Nasonia vitripennis
Parasitic wasp
Dendroctonus ponderosae
Mountain pine beetle
Tribolium castaneum
Red flour beetle
Pediculus humanus
Human body louse
Rhodnius prolixus
Kissing bug
Cimex lectularius
Bed bug
Acyrthosiphon pisum
Pea aphid
Zootermopsis nevadensis
Nevada dampwood termite
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X04PU )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Ixodes scapularis
Black-legged tick
Stegodyphus mimosarum
African social velvet spider
Tetranychus urticae
Two-spotted spider mite
Daphnia pulex
Water flea
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G09BB )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Ciona intestinalis
Vase tunicate
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (0)
No records found.
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Model Summary Ribbon
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Allele
Disease
Evidence
References
Potential Models Based on Orthology ( 1 )
Modifiers Based on Experimental Evidence ( 1 )
Allele
Disease
Interaction
References
Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Functional Complementation Data
Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
Interactions
Summary of Physical Interactions
esyN Network Diagram
Show neighbor-neighbor interactions:
Select Layout:
Legend:
Protein
RNA
Selected Interactor(s)
Interactions Browser

Please see the Physical Interaction reports below for full details
protein-protein
Physical Interaction
Assay
References
Summary of Genetic Interactions
esyN Network Diagram
esyN Network Key:
Suppression
Enhancement

Please look at the allele data for full details of the genetic interactions
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
External Data
Subunit Structure (UniProtKB)
PP2A exists in several trimeric forms, all of which consist of a core composed of a catalytic subunit associated with a 65 kDa regulatory subunit (PR65) (subunit A). The core complex associates with a third, variable subunit (subunit B), which confers distinct properties to the holoenzyme.
(UniProt, P36872 )
Linkouts
BioGRID - A database of protein and genetic interactions.
DroID - A comprehensive database of gene and protein interactions.
InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
MIST (genetic) - An integrated Molecular Interaction Database
MIST (protein-protein) - An integrated Molecular Interaction Database
Pathways
Signaling Pathways (FlyBase)
Positive Regulators of Wnt-TCF Signaling Pathway -
Positive regulators of canonical Wnt signaling up-regulate the pathway, resulting in the enhancement of transcriptional regulation mediated by β-catenin (arm).
Positive Regulators of Hedgehog Signaling Pathway -
Positive regulators of hedgehog signaling down-regulation the pathway, enhancing the activation of transcription of hh-responsive genes.
Metabolic Pathways
External Data
Genomic Location and Detailed Mapping Data
Chromosome (arm)
3R
Recombination map

3-49

Cytogenetic map
Sequence location
3R:10,126,129..10,139,772 [-]
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
85F13-85F14
Limits computationally determined from genome sequence between P{EP}Fmr1EP3517&P{PZ}tws02414 and P{PZ}jumu06439&P{lacW}l(3)j8B6j8B6
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
85F12-85F13
(determined by in situ hybridisation)
85F11-85F16
(determined by in situ hybridisation)
85F-85F
(determined by in situ hybridisation)
85E12-85E13
85F12--13
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Stocks and Reagents
Stocks (17)
Genomic Clones (18)
 

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (167)
 

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced
BDGP DGC clones
Other clones
Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

cDNA Clones, End Sequenced (ESTs)
Other clones
RNAi and Array Information
Linkouts
DRSC - Results frm RNAi screens
GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Laboratory Generated Antibodies
Commercially Available Antibodies
 
Cell Signaling Technology - Commercial vendor for primary antibodies and antibody conjugates.
Other Information
Relationship to Other Genes
Source for database identify of
Source for database merge of

Source for merge of: tws CG6235

Source for merge of: tws l(3)S061805

Source for merge of: l(3)S061805 l(3)S022361 l(3)S022440 l(3)S023013

Source for merge of: l(3)S061805 l(3)S035505b l(3)S043008b

Source for merge of: l(3)S061805 l(3)S075515b l(3)S022205b l(3)S023141a

Source for merge of: l(3)S061805 l(3)S134601a l(3)S146606 l(3)S091905

Source for merge of: l(3)S061805 l(3)S075902b l(3)S101413b l(3)S110008a

Source for merge of: l(3)S061805 l(3)S024834a l(3)S029701a l(3)S032708c

Source for merge of: l(3)S061805 l(3)S067915 l(3)S075110 l(3)S105605

Source for merge of: l(3)S061805 l(3)S060804 l(3)S061915 l(3)S110815

Source for merge of: l(3)S061805 l(3)S048013 l(3)S048507 l(3)S111515

Source for merge of: l(3)S061805 l(3)S042630 l(3)S043029 l(3)S119908

Source for merge of: l(3)S061805 l(3)S029403 l(3)S031006 l(3)S132907

Source for merge of: l(3)S061805 l(3)S026326 l(3)S027127 l(3)S141309

Source for merge of: l(3)S061805 l(3)S023206 l(3)S024838 l(3)S025806

Source for merge of: l(3)S061805 l(3)S060203 l(3)S067109b l(3)S069206a

Source for merge of: l(3)S061805 l(3)S076415 l(3)S080409 l(3)S088513

Source for merge of: l(3)S061805 l(3)S063110 l(3)S066017 l(3)S066813

Source for merge of: l(3)S061805 l(3)S049902 l(3)S052810 l(3)S053011

Source for merge of: l(3)S061805 l(3)S045519 l(3)S046918 l(3)S048006

Source for merge of: l(3)S061805 l(3)S032303 l(3)S033903 l(3)S042629

Source for merge of: l(3)S061805 l(3)S027313 l(3)S028707 l(3)S029110

Source for merge of: l(3)S061805 l(3)S025832 l(3)S025913 l(3)S026226

Source for merge of: l(3)S061805 l(3)S023309 l(3)S023938 l(3)S024455

Additional comments
Other Comments

tws is required for efficient recruitment of pericentriolar material.

tws is required for the stabilization of arm in response to wg signaling.

dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.

Identification: Enhancer trap expression pattern survey for loci expressed in the ring gland.

Identification: Enhancer trap screen designed to discover genes involved in the cellular aspects of defense mechanisms, as well as in melanotic tumor formation processes linked to blood cell disregulation.

tws is involved in the control of cell division.

The autosomal "FLP-DFS" technique (using the P{ovoD1-18} P{FRT(whs)} P{hsFLP} chromosomes) has been used to identify the specific maternal effect phenotype for the zygotic lethal mutation.

Mutant alleles are pupal lethal and cause pattern duplication in imaginal discs.

The modulation of the phosphatase activity by the B subunit of type 2A protein phosphatase encoded by tws is crucial for specification of neural cell identity.

Mutations cause abnormalities in mitosis, both in the early embryo and in the larval brain.

This locus encodes protein phosphatase 2A regulatory subunit. Mutants display intact lagging chromatids that have undergone separation from their sisters, but that remain at the position formerly occupied by the metaphase plate, as well as anaphase figures that show bridging chromatin having two centromeric regions.

tws mutants display a mirror image duplication of parts of the imaginal wing disc suggesting that regulation of protein phosphatase activity may play a critical role in the specification of imaginal disc patterns.

The tws gene product is a regulatory subunit of protein phosphatase 2 (PP2A), one of the major classes of serine/threonine phosphatases.

tws is an essential gene required during embryogenesis and late larval development.

Mutant alleles of tws are pupal lethal that display abnormal pattern formation in imaginal discs. tws gene product is highly homologous to the mammalian B subunits of protein phosphatase 2A.

Origin and Etymology
Discoverer
Etymology
Identification
External Crossreferences and Linkouts ( 106 )
Sequence Crossreferences
NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
Other crossreferences
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
KEGG Genes - Molecular building blocks of life in the genomic space.
modMine - A data warehouse for the modENCODE project
SignaLink - A signaling pathway resource with multi-layered regulatory networks.
Linkouts
BioGRID - A database of protein and genetic interactions.
Cell Signaling Technology - Commercial vendor for primary antibodies and antibody conjugates.
Cell Signaling Technology - Commercial vendor for primary antibodies and antibody conjugates.
DPiM - Drosophila Protein interaction map
DroID - A comprehensive database of gene and protein interactions.
DRSC - Results frm RNAi screens
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
FlyMine - An integrated database for Drosophila genomics
Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
MIST (genetic) - An integrated Molecular Interaction Database
MIST (protein-protein) - An integrated Molecular Interaction Database
Synonyms and Secondary IDs (103)
Reported As
Symbol Synonym
Pp2A-85F
l(3)01436
l(3)S022205b
l(3)S022361
l(3)S022440
l(3)S023013
l(3)S023141a
l(3)S023206
l(3)S023309
l(3)S023938
l(3)S024455
l(3)S024834a
l(3)S024838
l(3)S025806
l(3)S025832
l(3)S025913
l(3)S026226
l(3)S026326
l(3)S027127
l(3)S027313
l(3)S028707
l(3)S029110
l(3)S029403
l(3)S029701a
l(3)S031006
l(3)S032303
l(3)S032708c
l(3)S033903
l(3)S035505b
l(3)S042629
l(3)S042630
l(3)S043008b
l(3)S043029
l(3)S045519
l(3)S046918
l(3)S048006
l(3)S048013
l(3)S048507
l(3)S049902
l(3)S052810
l(3)S053011
l(3)S060203
l(3)S060804
l(3)S061915
l(3)S063110
l(3)S066017
l(3)S066813
l(3)S067109b
l(3)S067915
l(3)S069206a
l(3)S075110
l(3)S075515b
l(3)S075902b
l(3)S076415
l(3)S080409
l(3)S088513
l(3)S091905
l(3)S101413b
l(3)S105605
l(3)S110008a
l(3)S110815
l(3)S111515
l(3)S119908
l(3)S132907
l(3)S134601a
l(3)S141309
l(3)S146606
l(3)j11C8
l(3)s1801
Secondary FlyBase IDs
  • FBgn0004906
  • FBgn0010249
  • FBgn0010748
  • FBgn0010780
  • FBgn0011012
  • FBgn0011434
  • FBgn0028118
  • FBgn0037791
  • FBgn0060325
  • FBgn0060355
  • FBgn0060382
  • FBgn0060393
  • FBgn0060451
  • FBgn0060476
  • FBgn0060482
  • FBgn0060490
  • FBgn0060503
  • FBgn0060530
  • FBgn0060599
  • FBgn0060620
  • FBgn0060667
  • FBgn0060680
  • FBgn0060683
  • FBgn0060685
  • FBgn0060686
  • FBgn0060717
  • FBgn0060727
  • FBgn0060736
  • FBgn0060738
  • FBgn0060744
  • FBgn0060764
  • FBgn0060771
  • FBgn0060777
  • FBgn0060782
  • FBgn0060814
  • FBgn0060817
  • FBgn0060835
  • FBgn0060851
  • FBgn0060857
  • FBgn0060858
  • FBgn0060872
  • FBgn0060877
  • FBgn0060907
  • FBgn0060908
  • FBgn0060915
  • FBgn0060916
  • FBgn0060954
  • FBgn0060957
  • FBgn0060959
  • FBgn0060962
  • FBgn0060965
  • FBgn0060971
  • FBgn0060972
  • FBgn0060974
  • FBgn0060977
  • FBgn0060995
  • FBgn0060996
  • FBgn0061006
  • FBgn0061008
  • FBgn0061016
  • FBgn0061017
  • FBgn0061018
  • FBgn0061025
  • FBgn0061026
  • FBgn0061030
  • FBgn0061036
  • FBgn0061050
  • FBgn0061051
  • FBgn0061053
  • FBgn0061055
  • FBgn0061059
  • FBgn0061060
  • FBgn0061062
Datasets (0)
Study focus (0)
Experimental Role
Project
Project Type
Title
References (208)