FlyBase Gene Report: Dmel\gol

General Information

Symbol

Dmel\gol

Species

D. melanogaster

Name

goliath

Annotation Symbol

CG2679

Feature Type

protein_coding_gene

FlyBase ID

FBgn0004919

Gene Model Status

Current

Stock Availability

8 publicly available

Gene Snapshot

goliath (gol) encodes an E3 ubiquitin ligase, whose cellular substrates are unknown. During embyrogenesis gol is expressed in fusion-competence myoblasts of the somatic and visceral mesoderm. [Date last reviewed: 2019-03-07]

Other Summaries

Alliance
Auto summary
Gene Group
UniProtKB
Interactive Fly

Also Known As

Key Links

Genomic Location

Cytogenetic map

60F3-60F3

Sequence location

2R:25,072,627..25,084,347 [-]

Recombination map

2-107

RefSeq locus

NT_033778 REGION:25072627..25084347

Sequence

Get Decorated FASTA

Genomic Maps

GBrowse JBrowse

Help me choose

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

[Detailed GO annotations]

Gene Group (FlyBase)

GOLIATH UBIQUITIN LIGASES

Protein Family (UniProt)

Protein Signatures (InterPro)

Molecular Function (GO)
[Detailed GO annotations]

Experimental Evidence

Predictions / Assertions

ubiquitin protein ligase activity; zinc ion binding

Summaries

Gene Group (FlyBase)

GOLIATH UBIQUITIN LIGASES -: E3 (ubiquitin) ligases interact with both ubiquitin-E2 (ubiquitin-conjugating) enzymes and the target protein, transferring the ubiquitin from the E2 to the substrate. The Goliath (or GRAIL) E3 ligases possess transmembrane spanning domain, a protease-associated domain and a RING finger domain. (Adapted from FBrf0220873).

Protein Function (UniProtKB)

Regulation of gene expression during embryonic mesoderm formation. Putative role as transcription factor.

(UniProt, Q06003)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the GBrowse view of Dmel\gol or the JBrowse view of Dmel\gol for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.52

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

gol-RB

FBtr0072459

NM_166705

2583

461

gol-RC

FBtr0300178

NM_079140

3193

461

gol-RD

FBtr0300179

NM_001169829

2520

601

gol-RE

FBtr0306330

NM_001259588

3725

461

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

gol-PB

FBpp0072361

52.6

461

8.06

NP_726508

AAM68328

gol-PC

FBpp0289415

51.8

461

8.61

NP_523864

AAF47316

gol-PD

FBpp0289416

68.6

601

9.00

NP_001163300

ACZ94572

gol-PE

FBpp0297426

51.8

461

8.61

NP_001246517

AFH08270

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

461 aa isoforms: gol-PC, gol-PE

Additional Polypeptide Data and Comments

Reported size (kDa)

284 (aa); 32 (kD)

(Bouchard and Cote, 1993)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\gol using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

gol_1

Linkouts

Gene Ontology (7 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

ubiquitin protein ligase activity

inferred from sequence or structural similarity with FLYBASE:gzl; FB:FBgn0037442

(FlyBase Curators, 2008--)

inferred from biological aspect of ancestor with PANTHER:PTN001864905

(assigned by GO_Central )

(Gaudet et al., 2011)

zinc ion binding

inferred from sequence model

(Ying et al., 2011)

Biological Process (3 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

mesoderm formation

inferred from expression pattern

(assigned by UniProt )

(Bouchard and Cote, 1993)

protein ubiquitination

inferred from mutant phenotype

(Yamazaki et al., 2013)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

ubiquitin-dependent protein catabolic process

inferred from biological aspect of ancestor with PANTHER:PTN001864905

(assigned by GO_Central )

(Gaudet et al., 2011)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

endosome

inferred from direct assay

(Yamazaki et al., 2013)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

nucleus

non-traceable author statement

(assigned by UniProt )

(Bouchard and Cote, 1993)

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 11 -- 12

dorsal pharyngeal muscle primordium

(Fisher et al., 2012)

longitudinal visceral muscle primordium

(Fisher et al., 2012)

somatic muscle primordium

Comment: reported as muscle system primordium

(Fisher et al., 2012)

visceral muscle primordium

Comment: reported as muscle system primordium

(Fisher et al., 2012)

embryonic stage 13 -- 16

dorsal pharyngeal muscle

(Fisher et al., 2012)

embryonic/larval muscle system

(Fisher et al., 2012)

embryonic stage 11

mesoderm

(Cunha et al., 2010)

radioisotope in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 10 -- 14

mesoderm

(Cote et al., 1987)

pharyngeal muscle | presumptive

(Cote et al., 1987)

Additional Descriptive Data

gol transcripts were first detected in the mesoderm of stage 10 embryos, and in the pharyngeal muscle anlagen. Expression was not detected past stage 14.

(Cote et al., 1987)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

endosome

inferred from direct assay

(Yamazaki et al., 2013)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\gol in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\gol

View exonic expression by tissue for Dmel\gol

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0004919

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0004919

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG2679-RA;CG2679-RB

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG2679

Flygut - An atlas of the Drosophila adult midgut

FBgn0004919

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\gol

Stages(s) 11-12
Stages(s) 13-16

FlyBase Wiki

Image Based Resources

Alleles, Insertions, and Transgenic Constructs

Classical and Insertion Alleles ( 5 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 7 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of gol

Transgenic constructs containing regulatory region of gol

Deletions and Duplications ( 4 )

Disrupted in

Df(2R)ES1

(Cote et al., 1987)

Df(2R)GGG^d13

(He and Noll, 2013)

Df(2R)gsb

(Duman-Scheel et al., 1997, Cote et al., 1987)

Df(2R)Kr10

(Duman-Scheel et al., 1997, Cote et al., 1987)

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

gol^GD3528

viable, with Scer\GAL4^Mef2.PR

gol^GD3528

viable, with Scer\GAL4^pnr-MD237

gol^GD3528

viable, with Scer\GAL4^tin.CΔ4

gol^GD3528

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v7.1)

Homo sapiens (Human) (27)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\RNF150

12 of 15

Yes

Hsap\RNF130

10 of 15

Yes

Hsap\RNF149

8 of 15

Yes

Hsap\RNF128

7 of 15

Yes

Hsap\RNF133

5 of 15

Yes

Hsap\RNF148

5 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Yes

Hsap\RNF32

1 of 15

Yes

Hsap\RNF38

1 of 15

Hsap\RNF43

1 of 15

Yes

Hsap\RNF44

1 of 15

Hsap\RNF103

1 of 15

Yes

Hsap\RNF111

1 of 15

Hsap\RNF115

1 of 15

Hsap\RNF122

1 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

Yes

Hsap\ZNRF3

1 of 15

Hsap\ZSWIM2

1 of 15

Yes

Model Organism Orthologs (via DIOPT v7.1)

Mus musculus (laboratory mouse) (27)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Rnf150

12 of 15

Yes

Mmus\Rnf130

10 of 15

Yes

Mmus\Rnf149

8 of 15

Yes

Mmus\Rnf128

6 of 15

Yes

Mmus\Rnf133

5 of 15

Yes

Mmus\Rnf148

4 of 15

Yes

Mmus\Rnf215

2 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Yes

Mmus\Rnf32

1 of 15

Yes

Mmus\Rnf38

1 of 15

Mmus\Rnf43

1 of 15

Yes

Mmus\Rnf44

1 of 15

Mmus\Rnf103

1 of 15

Yes

Mmus\Rnf111

1 of 15

Mmus\Rnf115

1 of 15

Mmus\Rnf122

1 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Yes

Rattus norvegicus (Norway rat) (21)

Rnor\Rnf150

10 of 13

Yes

Rnor\Rnf149

8 of 13

Yes

Rnor\Rnf128

6 of 13

Yes

Rnor\Rnf130

6 of 13

Yes

Rnor\Rnf148

5 of 13

Yes

Rnor\Rnf133

3 of 13

Yes

Rnor\Rnf215

2 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Rnor\Rnf38

1 of 13

Rnor\Rnf43

1 of 13

Yes

Rnor\Rnf44

1 of 13

Rnor\Rnf115

1 of 13

Rnor\Rnf122

1 of 13

Yes

Rnor\Rnf126

1 of 13

Rnor\Rnf165

1 of 13

Rnor\Rnf181

1 of 13

Xenopus tropicalis (Western clawed frog) (18)

Xtro\rnf149

7 of 12

Yes

Xtro\rnf150

4 of 12

Yes

Xtro\chmp3

1 of 12

Xtro\pja2

1 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

Yes

Xtro\rnf32

1 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Yes

Xtro\rnf130

1 of 12

Yes

Xtro\rnf181

1 of 12

Xtro\znrf3

1 of 12

Danio rerio (Zebrafish) (29)

Drer\rnf150a

11 of 15

Yes

Drer\rnf150

10 of 15

Yes

Drer\rnf130

7 of 15

Yes

Drer\rnf128a

5 of 15

Yes

Drer\LOC100536511

3 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Yes

Drer\rnf32

1 of 15

Yes

Drer\rnf38

1 of 15

Drer\rnf44

1 of 15

Drer\rnf103

1 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Yes

Drer\si:ch211-59o9.10

1 of 15

Drer\si:ch211-81a5.1

1 of 15

Drer\si:ch1073-392o20.1

1 of 15

Yes

Drer\si:dkey-51a16.9

1 of 15

Yes

Drer\zgc:175214

1 of 15

Yes

Drer\znrf3

1 of 15

Drer\zswim2

1 of 15

Yes

Caenorhabditis elegans (Nematode, roundworm) (8)

Cele\H10E21.5

9 of 15

Yes

Cele\C32D5.10

1 of 15

Cele\cutl-19

1 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

Yes

Cele\ZK637.14

1 of 15

Arabidopsis thaliana (thale-cress) (3)

Atha\RMR1

2 of 9

Yes

Atha\AT1G71980

1 of 9

Atha\AT4G09560

1 of 9

Saccharomyces cerevisiae (Brewer's yeast) (3)

Scer\APE3

1 of 15

Yes

Scer\ASR1

1 of 15

Yes

Scer\YBR062C

1 of 15

Yes

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\SPAC57A7.09

2 of 12

Yes

Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG091905SY )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Dmel\gol

Drosophila suzukii

Spotted wing Drosophila

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA15425

Drosophila persimilis

Dper\GL16830

Drosophila willistoni

Dwil\GK21726

Drosophila virilis

Dvir\GJ21338

Drosophila mojavensis

Dmoj\GI18477

Drosophila grimshawi

Dgri\GH23135

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915070Z )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17013957

Glossina morsitans

Tsetse fly

Gmor\GMOY006452

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_02910

Mayetiola destructor

Hessian fly

Mdes\Mdes011466

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL012337

Anopheles darlingi

American malaria mosquito

Adar\ADAC003537

Anopheles gambiae

Malaria mosquito

Agam\AGAP010356

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ006498

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ006497

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W078P )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA009253

Danaus plexippus

Monarch butterfly

Dple\DPOGS216100-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL007866

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_07532

Tribolium castaneum

Red flour beetle

Tcas\GLEAN_07101

Pediculus humanus

Human body louse

Phum\PHUM457790

Cimex lectularius

Bed bug

Clec\CLEC011333

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI009067

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_06703

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X073Q )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Ixodes scapularis

Black-legged tick

Isca\ISCW003743

Stegodyphus mimosarum

African social velvet spider

Smim\KFM78329.1

Tetranychus urticae

Two-spotted spider mite

Turt\tetur24g00580

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_327936

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G09RT )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000011573

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v7.1)

Drosophila melanogaster (Fruit fly) (8)

Gene Symbol

Score

Source

Alignment

2 of 10

gzl

2 of 10

CG4325

1 of 10

CG7694

1 of 10

CG32850

1 of 10

Iru

1 of 10

mura

1 of 10

sip3

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Allele

Disease

Interaction

References

gol^GD3528

ameliorates Huntington's disease

modeled by Hsap\HTT^{128Q.1-336.UAS}

(Miller et al., 2010)

Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

RNF150; ring finger protein 150

12 of 15

RNF130; ring finger protein 130

10 of 15

RNF149; ring finger protein 149

8 of 15

RNF128; ring finger protein 128

7 of 15

300439

RNF133; ring finger protein 133

5 of 15

RNF148; ring finger protein 148

5 of 15

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

Summary of Genetic Interactions

esyN Network Diagram

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0004919

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

38006

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-107

Cytogenetic map

60F3-60F3

Sequence location

2R:25,072,627..25,084,347 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

60F3-60F3

Limits computationally determined from genome sequence between P{EP}CG2790^EP412&P{EP}CG3776^EP835 and P{EP}zip^EP856&P{PZ}l(2)10481⁰³²⁶³

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

60E9-60F11

(Bouchard, 1992)

Experimentally Determined Recombination Data

Location

2-107

(FlyBase, 2016)

2-111.8

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (8)

Bloomington

23834

w¹¹¹⁸; Mi{ET1}gol^MB03006

28785

y¹ v¹; P{TRiP.JF03213}attP2

40204

y¹ w^*; Mi{MIC}gol^MI04636

79889

y¹ sc^* v¹ sev²¹; P{TOE.GS02125}attP40

VDRC

v107822

P{KK108421}VIE-260B

v37435

w¹¹¹⁸; P{GD3528}v37435

v37434

w¹¹¹⁸; P{GD3528}v37434/TM3

v341994

P{hsFLP}1, y¹ w¹¹¹⁸; P{HD_CFD01341}attP40/CyO-GFP

Genomic Clones (13)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (60)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequences

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0004919

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

RE52734

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0004919

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

38006

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for identity of: gol CG2679

(Zhong, 1999.11)

Source for database merge of

Additional comments

Other Comments

gol gene expression is widespread in embryonic differentiating mesoderm, followed by a gradual shift to neural derivatives during late germband retraction.

(Bouchard and Cote, 1992)

Genomic organization of the gol transcription unit and spatial expression pattern has been determined. The gol coding sequence exhibits significant homology to regions of a human growth hormone coding gene.

(Bouchard and Cote, 1991)

Included in genetic and molecular analysis of the zipper-gooseberry region.

(Cote et al., 1987)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 46 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

38006

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q06003

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

A0A0B4K8B7

Other crossreferences

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0004919

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0004919

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

gol_1

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG2679

Flygut - An atlas of the Drosophila adult midgut

FBgn0004919

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

38006

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC007101

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG2679

modMine - A data warehouse for the modENCODE project

FBgn0004919

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0004919

DRSC - Results frm RNAi screens

FBgn0004919

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0004919

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG2679-RA;CG2679-RB

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0004919

FlyMine - An integrated database for Drosophila genomics

FBgn0004919

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

38006

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Synonyms and Secondary IDs (9)

Reported As

Symbol Synonym

Name Synonyms

Goliath

(Ying et al., 2011)

goliath

(Ciglar et al., 2014, Yamazaki et al., 2013, Hoopfer et al., 2008, Goldman and Arbeitman, 2007, Bouchard, 1992)

Secondary FlyBase IDs

FBgn0004375
FBgn0004899

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

References (63)

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